ライフサイエンスコーパス: reactive nitrogen species

1 as a biomarker of oxidative stress caused by reactive nitrogen species.

2 ) whose products are thought to remove toxic reactive nitrogen species.

3 hat counteract the effects of NO and related reactive nitrogen species.

4 se (iNOS) and increased production of NO and reactive nitrogen species.

5 ake, are major regulators of the response to reactive nitrogen species.

6 thers that are collaterally activated by the reactive nitrogen species.

7 prevent nitration of tyrosines caused by the reactive nitrogen species.

8 ese effects on TH of tetrahydrobiopterin and reactive nitrogen species.

9 reactivity and the interaction of CcOX with reactive nitrogen species.

10 e pathogen from the antimicrobial actions of reactive nitrogen species.

11 intracellular reactive oxygen species (ROS)/reactive nitrogen species.

12 tions and has been linked to the presence of reactive nitrogen species.

13 mage: hydroxyl radical, tyrosyl radical, and reactive nitrogen species.

14 d LDL and LDL modified by monocyte-generated reactive nitrogen species.

15 ate that circumvents the negative effects of reactive nitrogen species.

16 oprotein damage induced by this pathological reactive nitrogen species.

17 ts a specific marker of protein oxidation by reactive nitrogen species.

18 is sensitive to exogenously supplied ROS and reactive nitrogen species.

19 ble mechanism for recycling nitrate anion to reactive nitrogen species.

20 of beta-cells to reactive oxygen species and reactive nitrogen species.

21 eduction product of NO, remains an enigmatic reactive nitrogen species.

22 up-regulated activity of enzymes, generating reactive nitrogen species.

23 eduction to nitrite, nitric oxide, and other reactive nitrogen species.

24 ent of macrophages that produce microbicidal reactive nitrogen species.

25 H antagonizes the bacteriostatic activity of reactive nitrogen species.

26 erium to overcome the toxicity of Fe(II) and reactive nitrogen species.

27 e to redox modifications of its SH groups by reactive nitrogen species.

28 ion are dependent on protein modification by reactive nitrogen species.

29 ction or denitrification, bacteria encounter reactive nitrogen species.

30 ve oxygen species or decreased production of reactive nitrogen species, a situation of nitroso-redox

31 Thus, a reactive nitrogen species acts directly on the channel o

32 nd transcriptional regulation in response to reactive nitrogen species, allowing the bacteria to face

33 mportant role in the spatial distribution of reactive nitrogen species and consequently in ozone form

34 oncentrations of reactive oxygen species and reactive nitrogen species and contributes to tissue prot

35 thways available to monocytes for generating reactive nitrogen species and explored their potential c

36 (8-NO(2)-dG) DNA adducts are induced by the reactive nitrogen species and may be associated with the

37 This interaction between reactive nitrogen species and PGHS may provide new appro

38 gamma-Tocopherol is effective scavengers of reactive nitrogen species and prevents DNA bases nitrati

39 is theory predicts that interactions between reactive nitrogen species and reactive oxygen species pr

40 e for ytfE in resistance of H. influenzae to reactive nitrogen species and the antibacterial effects

41 can be used to identify proteins modified by reactive nitrogen species and to determine the specific

42 aptive response to nitric oxide (NO)-derived reactive nitrogen species and to iron limitation in the

43 They also show that reactive nitrogen species and tyrosyl radical (and conse

44 hese in vivo and in vitro findings implicate reactive nitrogen species and tyrosyl radical in MPTP ne

45 ants (e.g., O2, reactive oxygen species, and reactive nitrogen species) and toxic levels of certain m

46 clerotic lesions implicates tyrosyl radical, reactive nitrogen species, and hypochlorous acid in LDL

47 kill phagocytosed Escherichia coli, produce reactive nitrogen species, and retain S. Typhimurium wit

48 composed of various reactive oxygen species, reactive nitrogen species, and UV photons, shows great p

49 Reactive oxygen species and reactive nitrogen species are biological molecules that

50 There is evidence that reactive nitrogen species are implicated in diabetic vas

51 f labile Zn(2+), and its inter-relation with reactive nitrogen species, are poorly understood due to

52 phils generate reactive oxygen species (ROS)/reactive nitrogen species as a defense mechanism for the

53 tively, these results identify MPO-generated reactive nitrogen species as a physiologically plausible

54 (91)), a major source of microglial ROS, and reactive nitrogen species as candidate inhibitors of NPC

55 sis, and defense against reactive oxygen and reactive nitrogen species, as key determinants of its pa

56 sulted in sensitivity to reactive oxygen and reactive nitrogen species, as well as increased DNA dama

57 erate sustainable high concentrations NO and reactive nitrogen species at tumor sites after treatment

58 ought to be driven by production and loss of reactive nitrogen species by microorganisms in the soil.

59 n determining how DA neurons are affected by reactive nitrogen species by shifting the balance of the

60 etoxification of reactive oxygen species and reactive nitrogen species can protect neurons.

61 osure to C. jejuni and that nitric oxide and reactive nitrogen species comprise part of the innate de

62 ntial targets of reactive oxygen species and reactive nitrogen species could contribute to ERK1/2 act

63 d macrophages, and the resultant increase in reactive nitrogen species damages axons by injuring thei

64 otyrosine in HDL raises the possibility that reactive nitrogen species derived from nitric oxide migh

65 lycoxidation, the enzyme myeloperoxidase, or reactive nitrogen species derived from nitric oxide.

66 FAs) are the product of the reaction between reactive nitrogen species derived of nitric oxide (NO) a

67 al (lipid peroxidation) and 3-nitrotyrosine (reactive nitrogen species formation) protein adducts cau

68 to tyrosine nitration in vivo; 2) the major reactive nitrogen species formed by leukocyte peroxidase

69 Reactive nitrogen species formed from nitric oxide (NO)

70 Reactive nitrogen species, formed during oxidative stres

71 Recent studies have identified reactive nitrogen species generated by monocytes by way

72 Our observations raise the possibility that reactive nitrogen species generated by myeloperoxidase a

73 We now report that reactive nitrogen species generated by the MPO-H2O2-NO2-

74 Oxidative damage by reactive nitrogen species has been implicated in the pat

75 However, the ability of EPO to generate reactive nitrogen species has not yet been reported.

76 compounds indicate that tyrosyl radical and reactive nitrogen species have attacked tyrosine residue

77 Since MPO and MPO-derived HOCl, as well as reactive nitrogen species, have been implicated in the p

78 To investigate the involvement of reactive nitrogen species in atherogenesis, we quantifie

79 d the hypothesis that increased formation of reactive nitrogen species in biliary cirrhosis causes ni

80 the interplay of reactive oxygen species and reactive nitrogen species in cardiac signaling pathways

81 ng the concentrations of reactive oxygen and reactive nitrogen species in cells, tissues, and biologi

82 le nitric oxide synthase and accumulation of reactive nitrogen species in lung tissue and bronchoalve

83 nt control over the form and availability of reactive nitrogen species in marine environments.

84 The predominant reactive nitrogen species in mitochondria are nitric oxi

85 e BRB by a mechanism involving the action of reactive nitrogen species in promoting expression of VEG

86 ablished whether HDL proteins are damaged by reactive nitrogen species in the circulation or artery w

87 , these data indicate a significant role for reactive nitrogen species in the insulin exocytosis mech

88 rong evidence that myeloperoxidase generates reactive nitrogen species in vivo and that it operates i

89 , a global marker of protein modification by reactive nitrogen species, in proteins recovered from br

90 Des-nitro metabolite formation generated reactive nitrogen species, including nitric oxide (NO),

91 e/nitrative damage arising from formation of reactive nitrogen species, including peroxynitrite.

92 vel mechanism by which products generated by reactive nitrogen species induce dopaminergic neuron dea

93 em revealed that reactive oxygen species and reactive nitrogen species inhibit SufB extein ligation b

94 binding of nitrite to heme Fe, and that the reactive nitrogen species involved derives from nitrous

95 that the E. coli transcriptional response to reactive nitrogen species is a composite response mediat

96 thological conditions in which production of reactive nitrogen species is increased and that antinitr

97 NO), which has recently been identified as a reactive nitrogen species, is a challenging task.

98 ived radical species formed by reaction with reactive nitrogen species may account for inhibition of

99 Production of reactive nitrogen species may be one important pathway,

100 Reactive nitrogen species may play a mechanistic role in

101 real time, although peroxynitrite and other reactive nitrogen species may potentially contribute to

102 ted from macrophages may occur chemically by reactive nitrogen species-mediated protein modification,

103 ould lead to the sustained production of the reactive nitrogen species nitric oxide and peroxynitrite

104 In the presence of oxygen, NO and NO-related reactive nitrogen species nitrosate 4,5-diaminofluoresce

105 determine the effects of reactive oxygen and reactive nitrogen species on DDAH activity demonstrated

106 a powerful tool for exploring the impact of reactive nitrogen species on oxidative reactions in vivo

107 attributable solely to chemical quenching of reactive nitrogen species or reduction in mutation frequ

108 dase-generated reactive brominating species, reactive nitrogen species, or tyrosyl radicals in vitro

109 itrated at tyrosine residues in vitro by the reactive nitrogen species peroxynitrite and nitrogen dio

110 Reactive intermediates such as reactive nitrogen species play essential roles in the ce

111 Reactive oxygen species and reactive nitrogen species play important roles during im

112 uni viability was measured after exposure to reactive nitrogen species produced biochemically as acid

113 Reactive oxygen species and reactive nitrogen species produced by epithelial and inf

114 lmonella enterica serovar Typhimurium to the reactive nitrogen species produced by inducible nitric o

115 In low stenosis areas, diabetes enhanced reactive nitrogen species production, as evidenced by in

116 n under pathological conditions encompassing reactive nitrogen species production.

117 ) and several downstream effects of ROS/RNS (reactive nitrogen species) production such as inhibiting

118 ions, biomolecules, reactive oxygen species, reactive nitrogen species, redox potential, chemical rea

119 following haemorrhagic shock is mediated by reactive nitrogen species released within the airspaces

120 Blocking the generation of reactive nitrogen species relocated CD8(+) T cells into

121 tional regulators of the E. coli response to reactive nitrogen species remain to be identified becaus

122 tyrosine, markers of lipid peroxidation, and reactive nitrogen species, respectively, and an antibody

123 t, aniA, norB, and dnrN (encoding a putative reactive nitrogen species response protein) were express

124 acellular electrons by causing intracellular reactive nitrogen species (RNS) accumulation, suppressin

125 duction of reactive oxygen species (ROS) and reactive nitrogen species (RNS) and subsequent oxidative

126 stimulated reactive oxygen species (ROS) and reactive nitrogen species (RNS) are essential activators

127 Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are produced, in part, f

128 hort-lived reactive oxygen species (ROS) and reactive nitrogen species (RNS) are strongly coupled in

129 d by inducible nitric oxide synthase (iNOS), reactive nitrogen species (RNS) can kill Mycobacterium t

130 Higher AMP/ATP ratios and increased reactive nitrogen species (RNS) can lead to AMPK activat

131 ransplantational hepatic iNOS expression and reactive nitrogen species (RNS) formation (nitrite and n

132 Reactive nitrogen species (RNS) function as powerful ant

133 oQ sensor kinase lessens the cytotoxicity of reactive nitrogen species (RNS) generated by inducible n

134 ibutes to the resistance of this pathogen to reactive nitrogen species (RNS) generated from the nitri

135 damine-123 was used to quantify in real time reactive nitrogen species (RNS) generation by renal tubu

136 study, the effects of 1 mM sodium nitrite, a reactive nitrogen species (RNS) generator, and 0.5 mM pa

137 Reactive oxygen species (ROS) and reactive nitrogen species (RNS) have been implicated in

138 induced by reactive oxygen species (ROS) and reactive nitrogen species (RNS) in aerobic metabolism.

139 es produce reactive oxygen species (ROS) and reactive nitrogen species (RNS) in response to bacterial

140 that damage to the ETC following exposure to reactive nitrogen species (RNS) is less in co-cultured n

141 Elevated levels of nitric oxide (NO) and reactive nitrogen species (RNS) may link inflammation to

142 ants have increased airway concentrations of reactive nitrogen species (RNS) metabolites.

143 consistent with the idea that GSH scavenges reactive nitrogen species (RNS) other than NO.

144 Reactive nitrogen species (RNS) play an essential role i

145 that both reactive oxygen species (ROS) and reactive nitrogen species (RNS) play important roles in

146 (LTB(4)), reactive oxygen species (ROS), and reactive nitrogen species (RNS) production is unclear, a

147 Superoxide and ROS/reactive nitrogen species (RNS) productions were determi

148 Nitrogen dioxide is a highly toxic reactive nitrogen species (RNS) recently discovered as a

149 nt of both reactive oxygen species (ROS) and reactive nitrogen species (RNS) that act to further incr

150 a burgdorferi encounters potentially harmful reactive nitrogen species (RNS) throughout its infective

151 homatis genital infection, the production of reactive nitrogen species (RNS) via iNOS protects a sign

152 ty against reactive oxygen species (ROS) and reactive nitrogen species (RNS) was determined.

153 ts against reactive oxygen species (ROS) and reactive nitrogen species (RNS) was evaluated by in vitr

154 xynitrite ((-)OON horizontal lineO, PN) is a reactive nitrogen species (RNS) which can effect deleter

155 on and exposure to reactive oxygen (ROS) and reactive nitrogen species (RNS), allowing them to surviv

156 tion of reactive oxygen species (ROS) and/or reactive nitrogen species (RNS), and antioxidants or ROS

157 eration of reactive oxygen species (ROS) and reactive nitrogen species (RNS), and dopamine release we

158 ecifically reactive oxygen species (ROS) and reactive nitrogen species (RNS), has been proposed as an

159 Reactive nitrogen species (RNS), in particular nitric ox

160 r mechanism, this leads to the generation of reactive nitrogen species (RNS), including peroxynitrite

161 s, such as reactive oxygen species (ROS) and reactive nitrogen species (RNS), promote diseases such a

162 d pancreatic tumors and found that excessive reactive nitrogen species (RNS), such as nitrite, are ge

163 ediated by reactive oxygen species (ROS) and reactive nitrogen species (RNS), which can alter the bio

164 ever, GPX1 exerts an intriguing dual role in reactive nitrogen species (RNS)-related oxidative stress

165 it survives in the host despite exposure to reactive nitrogen species (RNS).

166 AMPK in parallel with increased detection of reactive nitrogen species (RNS).

167 rotyrosine, a stable biomarker of NO-induced reactive nitrogen species (RNS).

168 ntributes to the resistance of Salmonella to reactive nitrogen species (RNS).

169 duction of reactive oxygen species (ROS) and reactive nitrogen species (RNS).

170 selectivity of the reaction of Cys(203) with reactive nitrogen species (RNS).

171 -generated reactive oxygen species (ROS) and reactive nitrogen species (RNS).

172 ) leak, which drives increased generation of reactive nitrogen species (RNS).

173 somes/lysosomes by nitric oxide (NO)-derived reactive nitrogen species (RNSs) and/or superoxide-deriv

174 Reactive oxygen and reactive nitrogen species (ROS, RNS) formed in the inner

175 ylori strains to reactive oxygen species and reactive nitrogen species, stressors found in their natu

176 Reactive nitrogen species such as nitric oxide, peroxyni

177 high levels of nitric oxide (NO) and related reactive nitrogen species such as nitroxyl and peroxynit

178 vations strongly support the hypothesis that reactive nitrogen species such as ONOO- form in the huma

179 To explore the role of reactive nitrogen species such as ONOO- in the pathogene

180 nclude hydroxyl radical, tyrosyl radical, or reactive nitrogen species such as peroxynitrite.

181 Because nitric oxide (NO) and derived reactive nitrogen species target zinc ions and cysteine

182 ide inactivation and generation of cytotoxic reactive nitrogen species that attack DNA, lipids, and p

183 amage induced by peroxynitrite, an important reactive nitrogen species that causes a diversity of pat

184 was concluded that GlbN protects cells from reactive nitrogen species that could be encountered natu

185 Peroxynitrite and nitrogen dioxide (NO2) are reactive nitrogen species that have been implicated as c

186 rophages produce reactive oxygen species and reactive nitrogen species that have potent antimicrobial

187 Nitrites generate reactive nitrogen species that may cause damage to the l

188 for iNOS overexpression and the increase in reactive nitrogen species that promote damage in dystrop

189 e intense interest in pathways that generate reactive nitrogen species, the physiologically relevant

190 asbestos inhalation induces the formation of reactive nitrogen species, three groups of rats were exp

191 for therapies capitalizing on the ability of reactive nitrogen species to induce autophagy-mediated c

192 we investigated the ability of nitric oxide/reactive nitrogen species to kill two strains of C. jeju

193 Here we report that generation of reactive nitrogen species upon lipopolysacharide/interfe

194 atment of NAC solution creates predominantly reactive nitrogen species versus reactive oxygen species

195 Activation of iNOS to produce reactive nitrogen species was not necessary for vaccine

196 genes involved in the protective response to reactive nitrogen species were up-regulated in the bubo.

197 roxide (H2O2) and nitrite (NO2-) to generate reactive nitrogen species which convert tyrosine to 3-ni

198 These "reactive nitrogen species" will, in turn, mediate both o