ライフサイエンスコーパス: reactive oxygen intermediate

1 1beta, IL-6, inducible NO synthase, TNF, and reactive oxygen intermediate.

2 ss signals, such as DNA damage, hypoxia, and reactive oxygen intermediates.

3 thogen strain causes the rapid production of reactive oxygen intermediates.

4 hesion to endothelium followed by release of reactive oxygen intermediates.

5 ivity for growth and enhanced sensitivity to reactive oxygen intermediates.

6 to infection, which includes the release of reactive oxygen intermediates.

7 d inhibition in astrocytes is independent of reactive oxygen intermediates.

8 ous to our understanding of defenses against reactive oxygen intermediates.

9 ogression of renal disease via generation of reactive oxygen intermediates.

10 rom PPARgamma, to modulate the production of reactive oxygen intermediates.

11 and viability via a process(es) dependent on reactive oxygen intermediates.

12 e latter two compounds are known to generate reactive oxygen intermediates.

13 state acetate (PMA)-stimulated production of reactive oxygen intermediates.

14 ion and the subsequent massive production of reactive oxygen intermediates.

15 ic heavy metals and protection of cells from reactive oxygen intermediates.

16 n indirect effect of COX products, including reactive oxygen intermediates.

17 uivalents to protect cellular integrity from reactive oxygen intermediates.

18 to be activated by many compounds, including reactive oxygen intermediates.

19 gested organisms are likely to be exposed to reactive oxygen intermediates.

20 tor alpha-induced mitochondrial cell-derived reactive oxygen intermediates.

21 nst various inducers of apoptosis, including reactive oxygen intermediates.

22 ys 890, abolishing its ability to synthesize reactive oxygen intermediates.

23 known to be activated by a process involving reactive oxygen intermediates.

24 agonist salicylic acid and the synthesis of reactive oxygen intermediates.

25 tion via redox cycling and the generation of reactive oxygen intermediates.

26 DPH oxidase and the concomitant reduction in reactive oxygen intermediates.

27 dent phagocytosis and subsequent exposure to reactive oxygen intermediates.

28 of reactive nitrogen intermediates, but not reactive oxygen intermediates.

29 mediated in part by increased resistance to reactive oxygen intermediates.

30 ric oxide congener formed in the presence of reactive oxygen intermediates.

31 can react with oxygen to generate cytotoxic reactive oxygen intermediates.

32 ular iron to the parasite, and production of reactive oxygen intermediates.

33 N-acetyl cysteine (a scavenger of reactive oxygen intermediates) abolished the ability of

34 Imaging reactive oxygen intermediate activities in phagosomes re

35 , myeloid cells, and a combination of NO and reactive oxygen intermediates all contribute to a common

36 s synthesized at high levels by cells during reactive oxygen intermediate and nitrogen intermediate p

37 quinone), a redox cycling reagent, generates reactive oxygen intermediates and causes oxidative injur

38 nd ADCC activity, while DC failed to release reactive oxygen intermediates and demonstrated minimal A

39 ypersensitive cell death in soybean cells by reactive oxygen intermediates and functions independentl

40 as an antioxidant by directly reacting with reactive oxygen intermediates and has a vital role in de

41 istinct roles in P. aeruginosa resistance to reactive oxygen intermediates and heat.

42 Both reactive oxygen intermediates and iron deprivation are I

43 rin suppressed the TNF-induced production of reactive oxygen intermediates and lipid peroxidation.

44 Reactive oxygen intermediates and nitric oxide modulate

45 evidence from knock-out mice on the role of reactive oxygen intermediates and reactive nitrogen inte

46 Resistance to reactive oxygen intermediates and reactive nitrogen inte

47 cally or enzymatically generated halogenated reactive oxygen intermediates and reduced its survival i

48 Reactive oxygen intermediates and subsequent oxidative s

49 al cells is independent of the production of reactive oxygen intermediates and that the cytoprotectiv

50 ies of macrophages include the generation of reactive oxygen intermediates and the delivery of bacter

51 ence mechanism against endogenously produced reactive oxygen intermediates and the oxidative stress i

52 l trypanothione reductase system to detoxify reactive oxygen intermediates and to maintain redox home

53 s against the cumulative damaging effects of reactive oxygen intermediates and toxic electrophiles, w

54 nded on the generation of neutrophil-derived reactive oxygen intermediates and was blocked by inhibit

55 reas anti-Fas mAb-induced apoptosis utilizes reactive oxygen intermediates and, in turn, caspase-3 an

56 elevated sensitivity to hydrogen peroxide, a reactive oxygen intermediate, and decreased lung coloniz

57 tempt to establish a linkage between CYP2E1, reactive oxygen intermediates, and ethanol toxicity.

58 tic link between Abeta and the generation of reactive oxygen intermediates, and identify molecular ta

59 ift, serum starvation, increased osmolality, reactive oxygen intermediates, and increased or reduced

60 olysosomal killing mediated by nitric oxide, reactive oxygen intermediates, and L-tryptophan starvati

61 n of small molecules such as salicylic acid, reactive oxygen intermediates, and nitric oxide amplifie

62 ction of inducible nitric oxide synthase and reactive oxygen intermediates, and phagocytose P chabaud

63 violaceum is critically dependent in vivo on reactive oxygen intermediates, and these species are mod

64 integrin-induced adhesion and production of reactive oxygen intermediates, and to a lesser extent, F

65 imal when inducible NO synthase activity and reactive oxygen intermediates are both present.

66 IL-12, reactive nitrogen intermediates, and reactive oxygen intermediates are crucial immune compone

67 Although oxygen and reactive oxygen intermediates are not required for the e

68 cade, reactive nitrogen intermediates joined reactive oxygen intermediates as a biochemically paralle

69 o the media coincided with the production of reactive oxygen intermediates as demonstrated by the pre

70 These results implicate unquenched reactive oxygen intermediates as the stimulus that initi

71 production of conjugated salicylic acid and reactive oxygen intermediates, as well as spontaneous le

72 the membrane to protect M. tuberculosis from reactive oxygen intermediates at the bacterial surface.

73 SOK-1 is activated 3- to 7-fold by reactive oxygen intermediates, but is not activated by g

74 It is proposed that elevated production of reactive oxygen intermediates by cells expressing CYP2E1

75 The production of toxic reactive oxygen intermediates by host cells is known to

76 ania-degraded FN decreased the production of reactive oxygen intermediates by parasite-infected macro

77 mechanisms of macrophages are production of reactive oxygen intermediates by phagocyte oxidase (phox

78 nduced IL-6 production is mediated through a reactive oxygen intermediate-dependent pathway.

79 rsensitive response, including generation of reactive oxygen intermediates, deposition of phenolic co

80 These reactive oxygen intermediates dissociate from the enzyme

81 Subsequent steps that generate reactive oxygen intermediates diverge and reflect the ef

82 overed are heat-shock proteins, nucleotides, reactive oxygen intermediates, extracellular-matrix brea

83 n kinase C stimulation and the generation of reactive oxygen intermediates for downstream signaling.

84 s responses to signals, possibly mediated by reactive oxygen intermediates from both biotic and abiot

85 in the presence of arginine the formation of reactive oxygen intermediates from NO production by nNOS

86 e electronic states and reaction pathways of reactive oxygen intermediates generated by 77 K radiolyt

87 Reactive oxygen intermediates generated by neutrophils k

88 Reactive oxygen intermediates generated by the phagocyte

89 Leflunomide suppressed TNF-induced reactive oxygen intermediate generation and lipid peroxi

90 Both reactive oxygen intermediate generation and lipid peroxi

91 SNAP pretreatment inhibited reactive oxygen intermediate generation and lipid peroxi

92 These results suggest that reactive oxygen intermediate generation, after a brief i

93 te-induced delta psi(m) reduction, secondary reactive oxygen intermediate generation, cardiolipin deg

94 o hypoxia, reoxygenation after hypoxia, or a reactive oxygen intermediate (H(2)O(2)).

95 The reactive oxygen intermediate H2O2 can function as a sign

96 nine jugular vein endothelial cells with the reactive oxygen intermediate H2O2 induced a concentratio

97 ular glutathione levels or production of the reactive oxygen intermediate H2O2.

98 ntial (deltapsi(m)) and excess production of reactive oxygen intermediates have been implicated as ke

99 Both nitric oxide and reactive oxygen intermediates have been implicated in co

100 The roles of oxygen and reactive oxygen intermediates in apoptosis are unclear a

101 uced cytotoxicity and activated caspases and reactive oxygen intermediates in Jurkat cells but not in

102 nduced cytotoxicity, activated caspases, and reactive oxygen intermediates in Jurkat cells, but not i

103 rs reduced the killing, indicating a role of reactive oxygen intermediates in the candidacidal activi

104 cells, we examined the role of intracellular reactive oxygen intermediates in the regulation of Fas-m

105 present report, we investigated the role of reactive oxygen intermediates in TNF-induced signaling.

106 ial cells, we showed that pyocyanin-mediated reactive oxygen intermediates inactivate human vacuolar

107 s instead mediated through the generation of reactive oxygen intermediates, inasmuch as preincubation

108 Use of nitric oxide and reactive oxygen intermediate inhibitors failed to alter

109 tect against the damage of electrophiles and reactive oxygen intermediates is potentially a major str

110 algR mutant was examined for sensitivity to reactive oxygen intermediates, killing by phagocytes, sy

111 role of algU in P. aeruginosa sensitivity to reactive oxygen intermediates, killing by phagocytic cel

112 te did not affect cytosolic or mitochondrial reactive oxygen intermediate levels as monitored by flow

113 Recent observations suggest that reactive oxygen intermediates may play a role in IL-1 an

114 Although it is well established that reactive oxygen intermediates mediate the NF-kappaB acti

115 alter cellular redox state, suggesting that reactive oxygen intermediates might modulate eNOS expres

116 signaling through protein kinase C (PKC) and reactive oxygen intermediates of nonmitochondrial origin

117 e genetically deficient in the production of reactive oxygen intermediates (phox(-/-) mice) were foun

118 ral recently identified signaling molecules, reactive oxygen intermediates play a critical role in ac

119 Recent observations suggest that reactive oxygen intermediates play a role in tumor cell

120 is associated with diminished mitochondrial reactive oxygen intermediate production and Ca(2+) level

121 it significant defects in adhesion-dependent reactive oxygen intermediate production and degranulatio

122 me- and dose-dependent increase in secondary reactive oxygen intermediate production and loss of card

123 nother antioxidant, rotenone, which inhibits reactive oxygen intermediate production by inhibiting th

124 om l/l mice that was associated with reduced reactive oxygen intermediate production in vitro.

125 ess phagocytosis, bactericidal capacity, and reactive oxygen intermediate production, was also increa

126 er extent, FcgammaR-induced calcium flux and reactive oxygen intermediate production.

127 , exhaustion during VL influenced macrophage-reactive oxygen intermediate production.

128 ibited severe defects in MIP-2 secretion and reactive oxygen intermediates production.

129 ted by an oxidation-reduction equilibrium of reactive oxygen intermediates, pyridine nucleotides, and

130 include tumor cell killing, IL-1 secretion, reactive oxygen intermediate release, nitric oxide synth

131 hypoxia is often followed by reperfusion and reactive oxygen intermediate (ROI) generation, we examin

132 tioxidant, was used to perturb intracellular reactive oxygen intermediate (ROI) levels to assess the

133 Intracellular reactive oxygen intermediate (ROI) levels were increased

134 ants with Bgt resulted in the attenuation of reactive oxygen intermediate (ROI) production and salicy

135 The importance of reactive oxygen intermediate (ROI) production in antimic

136 decreased FcgammaR-induced calcium flux and reactive oxygen intermediate (ROI) production in respons

137 Viability and reactive oxygen intermediate (ROI) production were measu

138 in human prostate cancer cells is caused by reactive oxygen intermediate (ROI)-dependent activation

139 These mice are defective in the reactive oxygen intermediate (ROI)-generating phagocyte

140 was estimated by flow cytometric analysis of reactive oxygen intermediate (ROI)-induced 2',7'-dichlor

141 d apoptosis is preceded by 1) an increase in reactive oxygen intermediates (ROI) and 2) an elevation

142 nvestigated the hypothesis that RBC scavenge reactive oxygen intermediates (ROI) and nitric oxide (NO

143 n oxidative burst and the generation of both reactive oxygen intermediates (ROI) and NO.

144 ghtened susceptibility to representatives of reactive oxygen intermediates (ROI) and reactive nitroge

145 Reactive oxygen intermediates (ROI) and reactive nitroge

146 e to methionine and protect bacteria against reactive oxygen intermediates (ROI) and reactive nitroge

147 OS2-/-), defective in the production of both reactive oxygen intermediates (ROI) and reactive nitroge

148 ages by cytokines leads to the production of reactive oxygen intermediates (ROI) and reactive nitroge

149 This study examined the contribution of reactive oxygen intermediates (ROI) and reactive nitroge

150 of Mycobacterium bovis (Ravenel and BCG) to reactive oxygen intermediates (ROI) and reactive nitroge

151 Reactive oxygen intermediates (ROI) are strongly associa

152 Reactive oxygen intermediates (ROI) contribute to neuron

153 Generation of reactive oxygen intermediates (ROI) following antigen re

154 Reactive oxygen intermediates (ROI) generated in respons

155 Reactive oxygen intermediates (ROI) generated in respons

156 Reactive oxygen intermediates (ROI) have been viewed tra

157 nt study, we have tested the hypothesis that reactive oxygen intermediates (ROI) have the capacity to

158 The functional role of reactive oxygen intermediates (ROI) in activation-induce

159 Previous studies have implicated reactive oxygen intermediates (ROI) in lymphocyte apopto

160 lecule expression, and limited production of reactive oxygen intermediates (ROI) in response to stimu

161 teine and glutathione, suggesting a role for reactive oxygen intermediates (ROI) in the death process

162 Because recent evidence implicates reactive oxygen intermediates (ROI) in VSMC proliferatio

163 ion, since NADPH oxidase-mediated release of reactive oxygen intermediates (ROI) is a primary bacteri

164 e contributions of respiratory burst-derived reactive oxygen intermediates (ROI) versus reactive nitr

165 to kill tumor cells including TNF-alpha, NO, reactive oxygen intermediates (ROI), and Fas ligand (Fas

166 ugh controlling ATP synthesis, production of reactive oxygen intermediates (ROI), and release of cell

167 uce neutrophil chemotaxis, the generation of reactive oxygen intermediates (ROI), and the production

168 e modification of cellular macromolecules by reactive oxygen intermediates (ROI), often leading to ce

169 vation of several growth factor receptors by reactive oxygen intermediates (ROI).

170 t and in stimulating host cell production of reactive oxygen intermediates (ROI).

171 but reduces the plant's capacity to detoxify reactive oxygen intermediates (ROI).

172 s, and conditions that elevate the levels of reactive oxygen intermediates (ROI).

173 l (Delta psi(m)) and increased production of reactive oxygen intermediates (ROI).

174 ingly, inhibition of bactericidal mediators, reactive oxygen intermediates (ROIs) and reactive nitrog

175 idative mechanisms, but the roles of various reactive oxygen intermediates (ROIs) are not known.

176 res were treated with blue light to generate reactive oxygen intermediates (ROIs) by endogenous retin

177 involves the rapid generation and release of reactive oxygen intermediates (ROIs) by the NADPH oxidas

178 ive burst generating O2- and H2O2, and these reactive oxygen intermediates (ROIs) cue the induction o

179 Increased production of reactive oxygen intermediates (ROIs) in fibrotic livers

180 Extracellular reactive oxygen intermediates (ROIs) in plants were prop

181 ate phagocyte-derived superoxide and related reactive oxygen intermediates (ROIs) is the major defect

182 Reactive oxygen intermediates (ROIs) play a major role i

183 is is preceded by an exponential increase in reactive oxygen intermediates (ROIs) produced in mitocho

184 chemical mechanism involving ozone-generated reactive oxygen intermediates (ROIs), but not by NO(3) r

185 rane potential (deltapsim) and production of reactive oxygen intermediates (ROIs), mediate the imbala

186 idative burst leading to the accumulation of reactive oxygen intermediates (ROIs), which are thought

187 MV infection of SMCs generates intracellular reactive oxygen intermediates (ROIs).

188 nd, thus, to protect cellular integrity from reactive oxygen intermediates (ROIs).

189 sly exposes them to elevated levels of toxic reactive oxygen intermediates (ROIs).

190 tumor necrosis factor alpha (TNF alpha) and reactive oxygen intermediates (ROIs).

191 bition of nitric oxide synthase, addition of reactive oxygen intermediate scavengers, or the use of a

192 y signaling pathway effectors, as opposed to reactive oxygen intermediates, serve as the first line o

193 Perhaps species other than reactive oxygen intermediates should be considered as th

194 Nonetheless, these cells did not produce reactive oxygen intermediates, suggesting an inability t

195 athogen triggers the rapid production of the reactive oxygen intermediates superoxide (O2-) and hydro

196 s switch phenotypes, secreted molecules like reactive oxygen intermediates switch impact from pro- to

197 ein increases steady-state concentrations of reactive oxygen intermediates that simulate PKC and decr

198 nitric oxide and a parallel accumulation of reactive oxygen intermediates, the latter generated by N

199 or lower the threshold for its induction by reactive oxygen intermediates, these factors may repress

200 ty of Mycobacterium tuberculosis response to reactive oxygen intermediates, this organism has evolved

201 n the studied seawater by H(2)O(2) and other reactive oxygen intermediates took place at both high an

202 Mitochondrial generation of reactive oxygen intermediates was necessary and sufficie

203 n that has been shown to reduce synthesis of reactive oxygen intermediates, was activated in the wild

204 a photoinducible intracellular generator of reactive oxygen intermediates, was investigated for comp

205 Using a number of inhibitors of reactive oxygen intermediates we determined that other t

206 Flow cytometry analysis revealed that reactive oxygen intermediates were generated in CPT-trea

207 Reactive oxygen intermediates were identified as candida

208 Glomerular mesangial cells produce reactive oxygen intermediates when stimulated by interle

209 ell iron or by upregulating the synthesis of reactive oxygen intermediates (which could potentially r

210 g IL-6 and B cell survival factors, but also reactive oxygen intermediates, which can suppress lympho