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1 ng vesicles, presumably corresponding to the readily releasable pool.
2 n of recycling vesicles partitioned into the readily releasable pool.
3 ion, a putative regulator of the presynaptic Readily Releasable Pool.
4 A53T inhibited vesicle replenishment to the readily releasable pool.
5 from an increased number of vesicles in the readily releasable pool.
6 the proportion of recycling vesicles in the readily releasable pool.
7 also inhibited vesicle replenishment to the readily releasable pool.
8 is, and inhibits vesicle mobilization to the readily releasable pool.
9 may convert docked synaptic vesicles into a readily releasable pool.
10 e probability of release and the size of the readily releasable pool.
11 depleting the reserve pool and enhancing the readily releasable pool.
12 ing but is required for the full size of the readily releasable pool.
13 n overshoot pool approximately 1.8 times the readily releasable pool.
14 vesicle release preferentially involves the readily releasable pool.
15 utamate terminals, reducing release from the readily releasable pool.
16 the well-known exponential refilling of the readily releasable pool.
17 rs alter the equilibrium between reserve and readily releasable pools.
18 ization from the reserve pool to the docked (readily releasable) pool.
19 maturely, and redirecting them to refill the readily releasable pool after relaxation of the calcium
21 of simultaneously released vesicles) in the readily releasable pool and their replenishment time con
22 hange was associated with a reduction in the readily releasable pool and vesicle recycling which impa
23 t not CA1 synaptosomes by (1) increasing the readily releasable pool as tested by hypertonic sucrose;
25 that phorbol esters increase the size of the readily releasable pool at glutamatergic hippocampal syn
26 , and that Epac2 is required to maintain the readily releasable pool at MF synapses in the hippocampu
27 neurons in culture, the size of the autaptic readily releasable pool before and after stimulation of
28 nhanced in size to a greater extent than the readily releasable pool but is eliminated upon expressio
29 not caused by an increase in the size of the readily releasable pool but is instead associated with a
30 short-duration train, which interrogates the readily releasable pool, but depleted release elicited b
31 onversion of docked synaptic vesicles into a readily releasable pool by activating SNAREs for efficie
32 ogether, in this system replenishment of the readily releasable pool by the reserve vesicles was stri
33 ute places vesicles selectively into a small readily releasable pool comprising about 20% of vesicles
34 sites with low release probability, a large readily releasable pool, fast presynaptic calcium cleara
35 es exocytosis of synaptic vesicles after the readily releasable pool has either been physiologically
39 tter-containing synaptic vesicles (SVs), the readily releasable pool, is available for fast Ca(2+)-in
40 e pulse could be entirely accounted for by a readily releasable pool of approximately 200 vesicles.
42 alpha-methyl-p-tyrosine, which depletes the readily releasable pool of dopamine, cocaine was still c
43 that membrane-attached vesicles comprise the readily releasable pool of fusion-competent vesicles and
46 tion arising from an increase in size of the readily releasable pool of insulin SGs and enhanced SG p
47 , one holds that the first phase is due to a readily releasable pool of insulin-containing granules.
48 NEM induced a dose-dependent increase in the readily releasable pool of neurotransmitters but by itse
50 Since exocytosed vesicles are drawn from a readily releasable pool of packaged transmitter, enhance
51 tool with which to probe the function of the readily releasable pool of presynaptic vesicles at CNS s
52 his small GTPase in reducing the size of the readily releasable pool of SVs and in channeling retriev
55 , we directly measured the refilling of this readily releasable pool of synaptic vesicles after Ca(2+
56 al-GTPase signaling in the modulation of the readily releasable pool of synaptic vesicles and suggest
57 ethod can currently detect exocytosis of the readily releasable pool of synaptic vesicles at a hippoc
58 ering of Ca(2+) channels and the size of the readily releasable pool of synaptic vesicles at active z
59 iming and docking and their loss reduces the readily releasable pool of synaptic vesicles by up to 75
60 to be due to enhancement of the size of the readily releasable pool of synaptic vesicles docked at t
61 ontrolling the homeostatic modulation of the readily releasable pool of synaptic vesicles following i
62 e study revealed that pregabalin reduces the readily releasable pool of synaptic vesicles in an N-met
63 f donor and acceptor vesicles, mimicking the readily releasable pool of synaptic vesicles prior to an
64 the total extent of evoked release, size of readily releasable pool of synaptic vesicles, and releas
65 ssed isoforms, SV2A and SV2B, have a reduced readily releasable pool of synaptic vesicles, indicating
66 superfused synaptosomes, we have studied the readily releasable pool of synaptic vesicles, measured a
68 zed mutant of synaptotagmin 1 suppressed the readily releasable pool of synaptic vesicles, whereas wi
78 p) before hearing onset, and by an increased readily releasable pool of vesicles (RRP) thereafter.
79 nses are believed to mobilize sequentially a readily releasable pool of vesicles (RRP) underneath the
82 inal) prevented decreases in the size of the readily releasable pool of vesicles and in the percentag
83 though effects of phorbol esters both on the readily releasable pool of vesicles and on presynaptic c
84 Munc18-1 which results in a decrease in the readily releasable pool of vesicles at a synapse, sugges
85 However, with adaptation, depletion of the readily releasable pool of vesicles diminishes quantal c
86 pment, critical for the proper maturation of readily releasable pool of vesicles during early develop
87 asynchronous release completely empties the readily releasable pool of vesicles during sustained ele
88 ta produce PTP by increasing the size of the readily releasable pool of vesicles evoked by high-frequ
89 tained trains of activity suggested that the readily releasable pool of vesicles is reduced in Epac2(
91 of RIM1alpha causes a large reduction in the readily releasable pool of vesicles, alters short-term p
92 not due to an alteration of the size of the readily releasable pool of vesicles, but are attributabl
93 nts, enhanced synaptic depression, a smaller readily releasable pool of vesicles, delayed endocytosis
94 anges in mini frequency, mini amplitude, the readily releasable pool of vesicles, or the apparent Ca(
95 , region I mutations reduced the size of the readily releasable pool of vesicles, whereas the region
100 restricts release and limits the size of the readily-releasable pool of synaptic vesicles at the acti
101 ted the size, but not the properties, of the readily-releasable pool of vesicles at inhibitory synaps
102 the reserve pool first and subsequently the readily releasable pool over a period of several minutes
103 osis facilitated vesicle mobilization to the readily releasable pool, probably by clearing fused vesi
104 and of evoked-release amplitudes (indicating readily-releasable pool refilling) occurred within appro
105 e pool size and the rate of refilling of the readily releasable pool remain unaltered by latrunculin
106 esicle mobilization and replenishment of the readily releasable pool require GTP and Ca2+ but do not
107 cium dependence of the effective size of the readily releasable pool (RRP) also contributes to the ca
108 This change applies to the release of both a readily releasable pool (RRP) and a slower secondary poo
109 es, the physiologically measured size of the readily releasable pool (RRP) and the release probabilit
110 rphological and functional properties of the readily releasable pool (RRP) and the reserve pool of sy
112 hment of docked synaptic vesicles within the readily releasable pool (RRP) from synaptic vesicle clus
113 IH resulted in a significant increase in the readily releasable pool (RRP) of secretory granules, and
114 retardation of the rate of refilling of the readily releasable pool (RRP) of secretory granules.
116 During intense presynaptic activity, the readily releasable pool (RRP) of synaptic vesicles empti
117 that exceed the rate of replenishment of the readily releasable pool (RRP) of synaptic vesicles, depr
118 tonic solutions that measure the size of the readily releasable pool (RRP) of synaptic vesicles.
120 nd -2 suggested that complexin maintains the readily releasable pool (RRP) of vesicles and clamps spo
123 enerated uIPSCs in granule cells to evaluate readily releasable pool (RRP) size and resupply rate of
124 r, we show that another presynaptic feature, readily releasable pool (RRP) size, is tonotopically dis
125 ositional fate of vesicles endocytosed after readily releasable pool (RRP) stimulation in rat hippoca
126 Although it takes several seconds for the readily releasable pool (RRP) to refill during periods o
127 pid endocytosis recycles vesicles within the readily releasable pool (RRP) via a kiss-and-run mechani
128 e from nascent synapses without a functional readily releasable pool (RRP) was unresponsive to PMA ap
129 Tomo1 facilitates release efficacy from the Readily Releasable Pool (RRP), and regulates SV distribu
137 ipine, mainly control the fast fusion of the readily releasable pool (RRP); that is, they encode the
138 increase in release probability (Pr ) and/or readily-releasable pool (RRP) in many synapses, but the
139 increase in release probability (Pr ) and/or readily-releasable pool (RRP) in many synapses, but the
140 increase in release probability (Pr ) and/or readily-releasable pool (RRP) of synaptic vesicles (SVs)
141 lcium influx, and diminishes the size of the readily-releasable pool (RRP) of synaptic vesicles, cons
142 ctively, but does not change the size of the readily-releasable pool (RRP) of vesicles as measured by
143 stimulation revealed that as P declines, the readily releasable pool size (N) increases so that the n
145 dose-response fitting of Stx1 levels against readily releasable pool size and vesicular release proba
146 erely impaired, as demonstrated by a smaller readily releasable pool size, slower refilling rate of p
149 lized at synaptic ribbons participate in the readily releasable pool that is tapped rapidly during de
150 We tested this by selectively labeling the "readily releasable" pool, those vesicles released first
151 core complexes, to study the relation of the readily releasable pool to core complex assembly in syna
152 , we find Tomo1 actions to extend beyond the Readily Releasable Pool to mediate the Total Recycling P
153 sence of Doc2b, release was shifted from the readily releasable pool to the subsequent sustained comp
154 ve to [Ca2+]i than the previously described "readily releasable pool." Upon activation of PKC, this "
155 anipulation of the number of vesicles in the readily releasable pool using phorbol ester treatment su
157 nicotine-induced increase in the size of the readily releasable pool was blocked by alphaBgTx and by
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