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2 been lauded as novel solvents, but is there really a difference between them and concentrated aqueou
5 nel, leading us to suggest that FtsEX is not really a transporter even though it probably has to hydr
6 o conducted to verify whether C. elegans are really able to detect the rigidity of substrates or whet
7 ected to do so if the regression process was really able to identify independent differential gene ex
8 be asked: Is this amount of injury and death really acceptable for an over-the-counter pain reliever?
10 ankton communities in the Xiangxi River were really affected by environmental changes from the Three
13 suggests that the somatic ciliate genome is really an 'epigenome', formed through templates and sign
15 nd that N(alpha)-N(beta) bond "insertion" is really an intramolecular N(alpha) atom migration process
17 st frequently presented directions than they really are (estimation biases); and (ii) in the absence
18 em, there is disagreement about whether they really are a problem for researchers in the behavioral s
20 edisposes toward it; whether glucocorticoids really are plausible candidates for contributing to the
21 towards showing that such glycolipid domains really are present within both model and cellular membra
29 ken to represent "what psychiatric disorders really are." A flexible and more instrumentalist view of
30 kplace, such as whether the environments are really as distinct as they are often perceived to be, as
31 electrospray ionization (ESI), appear to be really attractive methods for the characterization of bi
35 ture dominant forest types in the north will really be dominated by oaks, as modelled via DISTRIB.
36 the systematic errors in published trees may really be far larger than the analytical methods (e.g.,
39 utionary computation (EC), but which has not really been applied in this way to experimental breeding
40 life cognitive decline and dementia risk may really begin with improving educational quality and acce
47 lly imposed polarity upon a filament that is really bipolar, with the two strands running in opposite
49 can be put to work to engineer systems that really can be called 'thought partners', systems built t
50 requency of carbohydrates consumption do not really capture boy's chronic hyperglycemia, boys being m
51 mpetition and viral defense, a situation not really captured by present idealized models that operate
53 95% confidence interval, 0.15-1.67; P=0.27) really close to nonhypogammaglobulinemic and nonsubstitu
56 d whether pretherapeutic factors and MRD are really competing or complementary tools to individualize
57 dant, in which case micrometeorite oxidation really constrains the CO(2)/N(2) ratio, not the total ox
60 gramme entitled 'Transplants: Are the Donors Really Dead?' Several United States experts not only dis
64 nown whether the dominant immune response is really directed against the skin or we have insufficient
67 he question of how much the analysis results really do differ, first at the gene level, then at the b
71 r cells that have differentiated into stalks really do retain the ability to make new tips, we have r
72 ples of treatments for serious disease which really do work extremely well, most claims for big impro
74 ur second aim was to see whether allopurinol really does reduce vascular tissue OS in CAD patients.
77 inequality, generally believed nonlocal, is really due to a series of three measurements (not two as
79 lunches were observed to determine what was really eaten and the results of these observations were
81 ong all the compounds, verteporfin (VER) was really efficient in enhancing PMN-mediated bacterial kil
82 clear, and needs a more focused approach to really elucidate what helps people stay mentally healthy
83 s, indicating a lack of understanding of the really emergent ocular pathologies among population.
84 hat that none of the experiments they review really establishes that human adults, infants, or nonhum
88 onfirm that isotope (22)Ne and regular CO(2) really exist in the output gas from reactors determined
93 perceptually close to real life and possibly really experienced by the actors, audiences may experien
96 n transfer processes, but also because it is really fruitful in the development of new analytical sen
98 euroscience, which will help neuroscience to really "go social"; this may also be relevant for our un
99 Woolf is also quoted as saying "nothing has really happened until it has been described," a harbinge
100 We conclude that the Aplysia feeding CPG really has a coherent internal network state whose dynam
102 ntal biologists to question whether ES cells really have an in vivo equivalent, or whether their prop
103 ients do not achieve CR2 and therefore never really have an opportunity for a potential curative ther
105 ell the authors, "Hey, you forgot to do this really important thing, without which it is hard to acce
107 ive care unit trials offers the potential to really improve our understanding of how the preterm brai
108 lex deep learning models in this case cannot really improve the prediction performance, with the best
113 this purpose, offering cheap and easy-to-use really integrated sensing systems for rapid on-site dete
114 g which of the proposed binding partners can really interact with CTX using biochemical methods and r
115 hat RAP2.12 protein level is affected by the REALLY INTERESTING GENE (RING) domain containing SEVEN I
116 esistance required increased expression of a really interesting gene (RING) domain-deficient BRCA1 pr
118 XIAP polyubiquitination is dependent on the really interesting new gene (RING) catalytic domain, (ii
119 r 1 (BRCA1) in complex with BRCA1-associated really interesting new gene (RING) domain 1 (BARD1) is a
120 s E3 ligase activity also requires an intact really interesting new gene (RING) domain because Iduna
121 hysical interaction is independent of IDOL's really interesting new gene (RING) domain E3 ligase acti
123 tor of the p53 tumor suppressor, possesses a Really Interesting New Gene (RING) domain within its C-t
124 ntains three hemerythrin (HHE) domains and a Really Interesting New Gene (RING) domain, interacts wit
126 hat contain one plant homeodomain (PHD), two really interesting new gene (RING) domains, and one set
127 ed on product distribution predicts that the really interesting new gene (RING) E3 enzymes SCF(Cdc4)
128 (CRBN), a substrate receptor of the cullin-4 really interesting new gene (RING) E3 ligase complex.
131 a large family of proteins that function as Really Interesting New Gene (RING) E3 ubiquitin ligases.
133 -associated ubiquitin-protein ligases in the Really Interesting New Gene (RING) family, PEX2, PEX10,
134 irus Ub ligase 2 (HUL-2) associated with the really interesting new gene (RING) finger domain encoded
135 nked gene Rnf12 encodes the ubiquitin ligase really interesting new gene (RING) finger LIM domain-int
137 , enhancer of zeste, and trithorax (SET) and really interesting new gene (RING) finger-associated (SR
138 is study that NKLAM contains a cysteine-rich really interesting new gene (RING) in between RING-RING
140 rix were believed to require the docking and really interesting new gene (RING) subcomplexes, protein
141 NDUCING TEMPERATURE 2 (CSIT2) that encodes a really interesting new gene (RING) type E3 ligase, contr
142 riant in MYCBP2, a gene encoding an atypical really interesting new gene (RING) ubiquitin ligase and
144 the ligase that also contains the essential Really Interesting New Gene (RING)-finger domain was suf
145 Arkadia's function in vivo depends on the really interesting new gene (RING)-H2 interaction with t
147 E3s, the E2 UBCH7 is unable to function with really interesting new gene (RING)-type E3s, thereby res
149 sociated factor 2 (TRAF2) mutant lacking the really interesting new gene and zinc finger domains (TRA
150 RCA1185delAG breast cancer cells expressed a really interesting new gene domain-less (RING-less) BRCA
151 s physically associated with RPW8.2 with its REALLY INTERESTING NEW GENE finger domain that is essent
152 s previously identified a role for RNF138, a really interesting new gene finger E3 ubiquitin ligase,
153 apices included the repression of genes for Really Interesting New Gene finger proteins and basic do
155 Early investigations of E3s of the RING (really interesting new gene) and HECT (homologous to the
156 ized by the presence of amino-terminal RING (really interesting new gene) and PHD (plant homeo domain
157 er 40S dissociation, placing the Ltn1p RING (Really Interesting New Gene) domain near the exit channe
159 fd2p has a fold similar to that of the RING (Really Interesting New Gene) domain that is present in c
160 -amino acid protein containing a C3HC4 RING (really interesting new gene) domain that may function as
161 E6-associated protein C terminus) or a RING (really interesting new gene) domain to catalyse polyubiq
162 tor receptor-associated factor 6) is a RING (really interesting new gene) domain ubiquitin (Ub) ligas
163 tripartite motif protein 2 (TRIM2), a RING (really interesting new gene) domain-containing protein.
165 ulated by several mechanisms including RING (Really Interesting New Gene) domain-mediated autoubiquit
168 r additional E3 ligases containing the RING (Really Interesting New Gene) finger domains that are inv
169 molecules from the intracellular GRAIL RING (really interesting new gene) finger to the small cytosol
170 These findings demonstrate that CUL3-RING (really interesting new gene) ligases that contain KLHL3
172 s study, we identified the Arabidopsis RING (really interesting new gene) type E3 ubiquitin ligase SP
175 three consecutive zinc-binding domains-RING (really interesting new gene), Bbox1, and Bbox2-that have
176 s, such as LIM (Lin-11, Isl-1, Mec-3), RING (really interesting new gene), PHD (plant homeodomain) an
178 is of the Arabidopsis thaliana RING-ANK (for Really Interesting New Gene-Ankyrin) family, a subgroup
180 y are controlled by ubiquitination involving really interesting new genes (RING) domain-containing pr
181 fferent molecular entities have created some really interesting structures for more than 15 years wit
187 the question of how effective social policy really is at reducing new infections that, left alone, c
188 y examining the evidence that G protein bias really is desirable and also by discussing whether the l
189 al. demonstrate that metabolism in brown fat really is increased when adult humans are exposed to col
190 r how prevalent Internet use for health care really is or what impact it has on health care utilizati
193 ortality enhancement must be dominant if ADE really is responsible for the immunological distance bet
194 ackie Gleason was wont to say: "How sweet it really is!" And--reflecting on the 1940s-1980s, when stu
197 Yet it remains unclear what personality really is: is it just the behavioural patterns themselve
198 with reviewers' comments ranging from "It is really just a show and tell paper and doesn';t have any
200 n a strong position to discover what animals really know about their fellow beings, be it based on si
204 emia per se on liver-related outcomes is not really known outside the human immunodeficiency virus co
206 arboxyl functionalized nanoparticles surface really leads to orthogonal or directed immobilization of
207 ss, some maintain that language models don't really learn language and also that, even if they did, t
208 "My religious or spiritual beliefs are what really lie behind my whole approach to life." Response o
211 ds obtained from isolation have proven to be really low (<0.01%), greatly hindering the study of thes
218 failed to understand what tissue engineering really means and to appreciate that engineering is synon
220 his review, we explore what treatment of AKI really means, discuss the emerging therapies, and examin
223 that seemingly affect one primary organ are really multiorgan diseases, with substantial secondary r
224 e clinical trials must focus on patients who really need adjunct cardioprotection, that is, those wit
226 ; careful consideration of whether questions really need to be answered, especially in cases where an
229 t up the question of whether antibiotics are really needed in the treatment of acute otitis media.
230 answers to the ultimate question: "Are they really needed or can bulk materials accomplish the same?
231 d does not belong because (i) a protein with really new fold may contain some structural fragments no
233 of reproducible error is low, then there is really no purpose in substantially allocating more resou
236 fects of negation ("not") and intensifiers ("really") on the representation of scalar adjectives (e.g
237 y cell wall signals and improving resolution really opens new avenues for the use of DNP-enhanced sol
241 pecies appear to thrive in places where they really persist only because individuals disperse into th
244 demonstrated on model samples that it is now really possible to perform dual beam depth profiling exp
249 occasion about how much value these studies really provide, it is clear that many of the strongest r
250 a veteran of the "good old days" (they were really quite bad), young physicians who hope to become c
251 ssion levels of classical reference genes is really quite huge (e.g. 44 fold for GAPDH in one data se
252 to believe that members of their gender are "really, really smart." Also at age 6, girls begin to avo
253 activities said to be for children who are "really, really smart." These findings suggest that gende
259 n unrelated individuals in non-human animals really resemble exchanges or are they a consequence of s
261 ns within anxiety-related brain circuits are really responsible for their anxiolytic effects and how
263 nal Ab titers and memory B cells, but how it really shapes the Ag-specific B cell compartment is poor
264 e technologies include microblogging, blogs, really simple syndication (RSS) feeds, podcasts, wikis,
265 ve that members of their gender are "really, really smart." Also at age 6, girls begin to avoid activ
266 ies said to be for children who are "really, really smart." These findings suggest that gendered noti
267 n that dogs are only able to smell when they really sniff, and that the temperature has an influence
268 of the Drosophila spinster and zebrafish not really started mutants suggest that these proteins may p
271 tion, and two flippers are indeed needed to "really swim," i.e., achieve high mechanosensitivity.
278 e argue that observed trait associations are really the phenomenon to be explained, and propose that
279 tablish that the observed photochemistry was really the result of a true single-step tri-pi-methane r
280 line, ring, mesh, and dot aggregates are not really the transmissible prion species and should only b
281 its to achieve statistical independence, are really theoretical hypotheses that warrant empirical con
284 ults demonstrate that both types of LECs are really two extremes of one class of electroluminescent d
285 "cloaca," which is Latin for sewer, they are really two separate entities in terms of surgical manage
287 diates and requires further investigation to really understand the mode of action and the origins of
288 normal in all forms of cancer, but it is not really understood how this occurs and what is its role i
290 ed as a step for determining whether one can really use the former to predict dosimetry of the latter
294 rm for oncologists and patients, oncologists really want to know which therapy to start for a given p
295 ess toward determining whether these objects really warp spacetime as predicted by the general theory
297 addition, a specific type of antibody worked really well with the new drug in blocking virus infectio