ライフサイエンスコーパス: receptor agonist

1 odel can be effectively treated with a GLP-1 receptor agonist.

2 uires novel chemical conversions to act as a receptor agonist.

3 ted with setmelanotide, a new melanocortin-4 receptor agonist.

4 the A-ring in its activity as a kappa-opioid receptor agonist.

5 than 30 min after removal of the muscarinic receptor agonist.

6 is a potent and selective neuropeptide Y Y4 receptor agonist.

7 ibed in the literature as a high affinity Y4 receptor agonist.

8 ce-daily tasimelteon, a novel dual-melatonin receptor agonist.

9 s were all mimicked by clonidine, an alpha-2 receptor agonist.

10 on induced by thermal pain or a kappa opioid receptor agonist.

11 was achieved following treatment with a THPO receptor agonist.

12 ectified by chronic administration of a TrkB receptor agonist.

13 afety profile similar to that of other GLP-1 receptor agonists.

14 igestive enzymes evoked by G-protein-coupled-receptor agonists.

15 hibitor, and glucagon-like peptide-1 (GLP-1) receptor agonists.

16 ially to several full GABA alpha1beta2gamma2 receptor agonists.

17 ulation with IL-1beta, PGE2, and specific EP receptor agonists.

18 rs, prostacyclin analogues, and prostacyclin receptor agonists.

19 events were highest with metformin and GLP-1 receptor agonists.

20 -related side effects reported for all GLP-1 receptor agonists.

21 al differences in intrinsic efficacy between receptor agonists.

22 erol and by ABC transporter-inducing liver X receptor agonists.

23 role in infections or response to Toll-like receptor agonists.

24 as food deprivation or prior exposure to MOP receptor agonists.

25 ce, even in the presence of potent Toll-like receptor agonists.

26 ) -activated K(+) current (BK) by purinergic receptor agonists.

27 has the potential to perform better than sst receptor agonists.

28 brain-state switching when exposed to GABAA-receptor agonists.

29 t release dopamine when exposed to glutamate receptor agonists.

30 iet or by applying topical TLR7/8 (Toll-like receptor) agonists.

31 tion of the C4alpha-methyl analog of mGlu2/3 receptor agonist 1 (LY354740).

32 The physiologic vitamin D receptor agonist, 1,25(OH)2D3 (calcitriol), is synthesiz

33 ns of GABA-A (muscimol) or GABA-B (baclofen) receptor agonists 15 to 20 minutes prior to injection of

34 er tested prostanoids, including the EP1/EP3 receptor agonist 17-phenyl trinor PGE2 and the partial F

35 demonstrates that the endogenous cannabinoid receptor agonists 2-arachidonoylglycerol (2-AG) and anan

36 orum brevis (FDB) fibers, either a ryanodine receptor agonist (4-chloro-meta-cresol) or depolarizing

37 otype in C57BL/6J mice by infusing the GABAA receptor agonist, 4,5,6,7-tetrahydroisoxazolo-[5,4-c]pyr

38 ministration of the broad-spectrum adenosine receptor agonist 5'-N-ethylcarboxamidoadenosine (NECA) p

39 The arylhydrocarbon receptor agonist 6-formylindolo[3,2-b] carbazole (FICZ),

40 Three 5-HT1A receptor agonists (8-OH-DPAT, F13714 and F15599) and one

41 tonin (5-HT)2C receptor antagonists, a 5-HT4 receptor agonist, a 5-HT7 receptor antagonist, NMDA rece

42 Albiglutide is a glucagon-like peptide-1 receptor agonist, a new class of drugs used to treat typ

43 also prevents hyperalgesia induced by a CD44 receptor agonist, A6.

44 Synthetic arginine vasopressin (AVP) receptor agonists able to induce systemic and mesenteric

45 Adiponectin receptor agonists abrogated ex vivo fibrotic responses i

46 The degree to which MOP receptor agonists act on different VTA circuits depends

47 e (MOP)/nociceptin-orphanin FQ peptide (NOP) receptor agonist activity to achieve this objective.

48 thyl diastereomer (3) possessed dual mGlu2/3 receptor agonist activity.

49 Exendin-4, a glucagon-like peptide-1 (GLP-1) receptor agonist administered twice daily via s.c. injec

50 tration of an arginine vasopressin 1A and 1B receptor agonist against 1) no treatment, 2) oxytocin, a

51 clinical study with eltoprazine, a 5-HT1A/B receptor agonist, against L-DOPA-induced dyskinesias in

52 ingolimod was found to be a nonselective S1P receptor agonist, agonism specifically of S1P1 is respon

53 ist 17-phenyl trinor PGE2 and the partial FP receptor agonist AL-8810, were uniformly abolished by th

54 Although soluble receptor agonist alone could not induce death, combinato

55 The P2X receptor agonist alpha,beta-methylene ATP (alpha,beta-me

56 cells from MM patients primed with the IL-15 receptor agonist ALT-803 in vivo displayed enhanced ex v

57 n the benzyl ring of the abscisic acid (ABA) receptor agonist AM1 optimizes its binding to ABA recept

58 Consistent with these results, CB2 receptor agonists AM1241 and GW405833 inhibited GABAergi

59 Our findings demonstrate how a plant receptor agonist and antagonist define inhibitory and in

60 h mixed opioid effects (mu- and kappa-opioid receptor agonist and delta-opioid receptor antagonist),

61 here a quantitative and panoramic measure of receptor agonist and modulator equi-response and equi-oc

62 s, incorporating ropinirole as a dopamine D2 receptor agonist and ZM 241385 as an adenosine A2A recep

63 r mammalian biogenic amine G protein-coupled receptor agonists and antagonists, some ligands had dram

64 Both glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors

65 erapies (i.e., glucagon-like peptide [GLP]-1 receptor agonists and dipeptidyl peptidase-4 inhibitors)

66 nces in network utilization by different EGF receptor agonists and highlight the need to characterize

67 Glucagon-like peptide-1 (GLP-1) receptor agonists and sodium-glucose co-transporter-2 (S

68 Prostanoid receptor agonists and the combination thereof with forsk

69 afety, in particular, for the thrombopoietin receptor agonists and the occurrence of late remissions.

70 inhibited by idremcinal, a macrolide motilin receptor agonist, and by synthesized macrolide derivativ

71 ural compound known to function as an opioid-receptor agonist, and is undergoing clinical trials for

72 ptidase-4 inhibitor, glucagon-like peptide-1 receptor agonist, and sodium-glucose cotransporter 2 inh

73 ents include benzodiazepines, benzodiazepine-receptor agonists, and cognitive behavioural therapy.

74 rugs that work on the incretin system, GLP-1 receptor agonists, and dipeptidyl peptidase-4 inhibitors

75 with l-dopa (levodopa) and various dopamine receptor agonists, and resulting rotational behaviors we

76 ined with metformin, DPP-4 inhibitors, GLP-1 receptor agonists, and SGLT-2 inhibitors and increased w

77 a humanized glucagon-like peptide-1 (GLP-1) receptor agonist antibody by first introducing a coiled-

78 e-presented CD40 ligand (mCD40L), as soluble receptor agonists are but weakly pro-apoptotic.

79 Muscarinic receptor agonists are characterized by apparently strict

80 Glucagon-like peptide-1 (GLP-1) receptor agonists are effective glucose-lowering drugs.

81 Glucagon-like peptide-1 (GLP-1) receptor agonists are effective therapies for the treatm

82 Radiolabeled somatostatin (sst) receptor agonists are integral to the diagnosis of gastr

83 ts in delivery methods for insulin and GLP-1 receptor agonists are paving the way towards better pati

84 Toll-like receptor agonists are potent enhancers of innate antivir

85 Dissociated sterol-based liver X receptor agonists as therapeutics for chronic inflammato

86 Notably, cannabinoid receptor agonists as well as inhibitors of endocannabino

87 Pretreatment with the potent NOP receptor agonist AT-202 (0.3-3 mg/kg) increased nicotine

88 n, we profiled the pharmacology of histamine receptor agonists at the two most abundant hH3R splice v

89 inhibitors and some glucagon-like peptide-1 receptor agonists, at least in the short term.

90 th a 5-HT2A receptor antagonist and a 5-HT2C receptor agonist attenuated the MDMA-induced increase in

91 nhalation of the nonsteroidal glucocorticoid receptor agonist AZD5423 effectively reduced allergen-in

92 ct of an inhaled nonsteroidal glucocorticoid receptor agonist, AZD5423, on allergen-induced responses

93 The GABAB receptor agonist baclofen also inhibited inward currents

94 The orthosteric GABAB receptor agonist baclofen has been shown to suppress ope

95 ty of SOM-IPSCs, but not PV-IPSCs to a GABAb receptor agonist baclofen.

96 adenosine receptor agonist NECA and the A2B receptor agonist BAY60-6583.

97 d scarring, the ability of beta 2 adrenergic receptor agonist (beta2ARag) to alter HDF differentiatio

98 euronally directed effects of the retinoid X receptor agonist bexarotene in an aggressive model of AD

99 However, the mechanism by which GLP-1 receptor agonists boost insulin secretion remains unclea

100 tio that was identical to that of unliganded receptors, agonist-bound D2 receptor-ligand complexes re

101 Unlike MOP receptor agonists, BU08028 at antinociceptive doses and

102 tolerability profile of bifunctional MOP/NOP receptor agonists, but also provide a means of translati

103 trials showed cardiovascular safety of GLP-1 receptor agonists, but results for cardiovascular effica

104 Selective D4 receptor agonists, by specifically targeting these termi

105 ke-promoting systems, whereas benzodiazepine receptor agonists (BzRAs) such as zolpidem (ZOL) induce

106 , placebo-controlled study with the dopamine receptor agonists cabergoline (a D2 agonist) and pergoli

107 These results also suggested that a receptor agonist can be switched to an antagonist by sub

108 nogram b-wave from cones, whereas a dopamine receptor agonist can potentiate the cone-driven b-wave o

109 loserine (DCS), which is a glycine site NMDA receptor agonist, can enhance extinction of conditioned

110 phoretically applied the general cholinergic receptor agonist carbachol onto neurons in dorsolateral

111 show cardiovascular safety across all GLP-1 receptor agonist cardiovascular outcome trials and sugge

112 shed human platelets with protease-activated receptor agonists caused translocation of Akt to the mem

113 treated with the selective beta3 adrenergic receptor agonist CL 316, 243 and underwent metabolic cag

114 Treatment with the beta3-adrenergic receptor agonist CL316,243 increased Cx43 expression and

115 In humans, the alpha2-adrenergic receptor agonist clonidine increases decisiveness in tas

116 TLRA/C-type lectin receptor agonist combinations were screened for enhancem

117 ediction that cimetidine, a histamine-2 (H2) receptor agonist commonly used to treat peptic ulcers, w

118 at assessed the safety and efficacy of GLP-1 receptor agonists compared with placebo in adult patient

119 Because pattern recognition receptor agonists continue to show more clinical benefit

120 Intrathecal injection of the mu-opioid receptor agonist [D-Ala(2), NMe-Phe(4), Gly-ol(5)]-enkep

121 through both pathways, whereas the mu opioid receptor agonist DAMGO decreased D2-receptor activity on

122 f mpkCCD14 cells with the type 2 vasopressin receptor agonist dDAVP increased mRNA and protein levels

123 ogenous administration of the glucocorticoid receptor agonist dexamethasone-compared with placebo-dur

124 ore and after exposure to the glucocorticoid receptor agonist dexamethasone.

125 We found that a synthetic glucocorticoid receptor agonist, dexamethasone, reduces cell proliferat

126 Here, we demonstrate that delta opioid receptor agonists differentially recruit arrestin isofor

127 tive enantiomer of the selective and full D1 receptor agonist dihydrexidine (DAR-0100A) could attenua

128 aserin is a serotonin 5-hydroxytryptamine 2c receptor agonist effective in treating obesity.

129 Finally, we find that estrogen receptor agonists elicit a behavioral fingerprint anti-c

130 The thrombopoietin receptor agonist eltrombopag has been shown to be safe,

131 The oral thrombopoietin receptor agonist eltrombopag is approved for treatment o

132 en, and 3) assess the ability of the motilin receptor agonist erythromycin to induce food intake.

133 The GLP-1 receptor agonist exenatide activated SERCA but did not a

134 acy and safety of co-initiation of the GLP-1 receptor agonist exenatide and the SGLT2 inhibitor dapag

135 The short-acting glucagon-like peptide 1 receptor agonist exenatide reduces postprandial glycemia

136 w that intra-VTA administration of the GLP-1 receptor agonist exendin-4 (0.05 mug) significantly redu

137 Cotreatment with the GLP-1 receptor agonist exendin-4 reversed the lysosomal dysfun

138 gon were engineered into the selective GLP-1 receptor agonist exendin-4, resulting in hybrid peptides

139 a number of high potency and efficacy mGlu2 receptor agonists exhibiting low potency mGlu3 partial a

140 tonin reuptake blocker, and the type 2 and 3 receptor agonists facilitated glutamatergic transmission

141 inuous delivery of a glucagon-like peptide-1 receptor agonist for 6-12 months and once-weekly tablets

142 BU08028 in monkeys using clinically used MOP receptor agonists for side-by-side comparisons in variou

143 y of 3 doses of ABT-126, an alpha7 nicotinic receptor agonist, for the treatment of cognitive impairm

144 o assess eltrombopag, an oral thrombopoietin receptor agonist, for thrombocytopenia (grade 4) treatme

145 elanocortin system consists of five reported receptors, agonists from the proopiomelanocortin gene tr

146 Glucagon-like peptide 1 (GLP-1) receptor agonists (GLP-1-RAs) act on multiple tissues, i

147 Once-weekly glucagon-like peptide-1 receptor agonists (GLP-1RAs) are new drugs for the treat

148 ased on this screen, we formulated a liver X receptor agonist (GW3965) and abolished its liver toxici

149 INT-777 (50 muM), but not by the farnesoid X receptor agonist, GW4064 (10 muM).

150 droxyheptanoic acid methyl ester), a lipoxin receptor agonist, has been previously confirmed to be eq

151 -4 (EX-4), a glucagon-like peptide-1 (GLP-1) receptor agonist, has been shown to reduce food intake a

152 Exenatide, a glucagon-like peptide-1 (GLP-1) receptor agonist, has neuroprotective effects in preclin

153 Obeticholic acid, a farnesoid X receptor agonist, has shown potential benefit in patient

154 GLP-1 receptor agonists have a favourable risk-benefit balance

155 Glucagon-like peptide-2 receptor agonists have therapeutic potential for the tre

156 ompounds such as BIM-23A760, an sst2/sst5/D2 receptors-agonist, have emerged as promising new approac

157 r treatment with the epidermal growth factor receptor agonist heparin-binding EGF (HB-EGF), which pro

158 s the effect of treatment with cannabinoid-2 receptor agonist HU-308 in the oral health of rats subje

159 A separate concern is that benzodiazepine receptor agonist hypnotics can cause parasomnias, which

160 model of ischemia-reperfusion injury, sigma1-receptor agonists improved postischemic survival and ren

161 erone or fluvoxamine, a high-affinity sigma1-receptor agonist, improved survival, renal function and

162 ne after stimulation with protease-activated receptor agonists in a Gq-dependent manner, with the kin

163 on, and they implicate inhaled A2B adenosine receptor agonists in ALI treatment.

164 e reference compound, (68)Ga-DOTATOC (an sst receptor agonist), in PET imaging.

165 ve to liraglutide, a glucagon-like peptide 1 receptor agonist, in Zucker diabetic fatty (ZDF) rats.

166 or fibroblastic cells with G protein-coupled receptor agonists, including angiotensin II or bombesin,

167 significantly potentiated the effects of CB2 receptor agonists, including the endocannabinoid 2-arach

168 Furthermore, a D3 receptor agonist increased choice of the disadvantageous

169 Consequently, a selective BLT2-receptor agonist increased thermal and mechanical withdr

170 We also show that a PGE2 receptor agonist increased, whereas a PGE2 synthase inhi

171 me, that activation of S1P2 with a selective receptor agonist increases cell viability and reduces ci

172 that treatment of myeloid cells with nuclear receptor agonists increases expression of phagocytosis-r

173 sis, and it was mimicked and occluded by CB1 receptor agonists, indicating it was mediated by the ret

174 Glucagon-like peptide 1 (GLP-1) receptor agonists induce weight loss, increase insulin s

175 Intranasal exposure with receptor agonists induced the release of IL-33 and subse

176 by microinjection of small amounts of GABAA-receptor agonists into an upper brainstem region named t

177 different concentrations of quinpirole, a D2 receptor agonist, into a brain slice containing the dors

178 ddicted pregnant women on long-acting opioid receptor agonist is the most common strategy to manage d

179 plasticity and intranasal treatment with C3a receptor agonists is an attractive approach to improve f

180 roughout the body, obtaining highly specific receptor agonists is essential.

181 Liraglutide, a long-acting GLP-1 receptor agonist, is approved for treatment of obesity;

182 Fingolimod, a sphingosine-1-phosphate receptor agonist, is used for the treatment of multiple

183 hesis-suppressing drugs, such as farnesoid X receptor agonists, is greatest when optimal adaptation i

184 c responsiveness to local puffs of the GABAA receptor agonist isoguvacine.

185 The selective CB2 receptor agonist JWH-133 induced a moderate migratory re

186 t hippocampal slices were treated with a CB2 receptor agonist (JWH133 or GP1a) for 7-10 days, quantal

187 ination with a long-acting beta2 -adrenergic receptor agonist (LABA) on GCM in the bronchial epitheli

188 ion, eltrombopag, a synthetic thrombopoietin-receptor agonist, led to clinically significant increase

189 lite II (sigma-1 receptor antagonist/sigma-2 receptor agonist ligand) obtained by conjugation to valp

190 e the effects of the glucagon-like peptide-1 receptor agonist liraglutide added to clozapine or olanz

191 ous injections of either the synthetic GLP-1 receptor agonist liraglutide in a dose-escalating regime

192 More recently, the glucagon-like peptide-1 receptor agonists liraglutide and semaglutide also reduc

193 tor sitagliptin, the glucagon-like peptide 1-receptor agonist lixisenatide based on presently availab

194 atients with a clinically-approved serotonin receptor agonist (lorcaserin, Belviq(R)) and observed so

195 Tier 1 options (rituximab, thrombopoietin receptor agonists, low-dose corticosteroids) have a rela

196 X71743, and a newly described Group III mGlu receptor agonist, LSP4-2022, to elucidate the role of mG

197 additional proof of principle that an apelin receptor agonist may be of therapeutic use in PAH in hum

198 mmunosuppressant therapy with thrombopoietin-receptor agonists may be a good strategy for management

199 rsistent inflammation and that selective CB2 receptor agonists may be useful for treatment of persist

200 inct combinations of TLRAs and C-type lectin receptor agonists may enhance Th1 responses of newborn D

201 Glucagon-like peptide-1 receptor agonists may have additional effects, such as w

202 Central administration of the melanocortin receptor agonist melanotan II in mutant mice reversed al

203 ation and propose that selective EP2 and EP4 receptor agonists might serve as a promising therapeutic

204 tested whether eltrombopag, a thrombopoietin receptor agonist, might be effective in improving thromb

205 The IP receptor agonist MRE-269 increased intracellular 3',5'-c

206 o specific parietal circuits using the GABAA receptor agonist muscimol and validated the lesion place

207 examined the effects of injecting the GABAA receptor agonist muscimol or the GABAA receptor antagoni

208 we reversibly inactivated the vSub with GABA receptor agonists (muscimol+baclofen) before the context

209 ect of inosine was mimicked by the adenosine receptor agonist NECA and the A2B receptor agonist BAY60

210 The adenosine receptor agonist NECA inhibited interferon-gamma and sti

211 )NH2, were compared with the reference GLP-1 receptor agonist [Nle(14),Lys(40)(Ahx-DOTA-(68)Ga)NH2]Ex

212 boline, an anxiogenic inverse benzodiazepine receptor agonist, normalized alcohol preference in EFhd2

213 ading rosettes by distinct G protein-coupled receptor agonists, notably lysophosphatidic acid (LPA; a

214 d CXCL10, CXCL8, and CCL5 as Galphai-coupled receptor agonists of potential interest.

215 We examined the acute effect of GLP-1 receptor agonists on coronary smooth muscle cells (CSM)

216 We assessed anamorelin, a novel ghrelin-receptor agonist, on cachexia in patients with advanced

217 died effects of GLP-1 and exendin-4, a GLP-1 receptor agonist, on gamma-aminobutyric acid (GABA) sign

218 G49, a dual glucagon-like peptide-1/glucagon receptor agonist, on NASH and hepatic regeneration.

219 a potent non-steroidogenic pan-melanocortin receptor agonist, on the lipopolysaccharide elicited pod

220 s, GABAA receptor activators, a serotonin 2C receptor agonist, opioid antagonist, dopamine-norepineph

221 arget organ, exogenous administration of AT2 receptor agonists or angiotensin 1-7 analogs may similar

222 eceptors to ACh was mimicked by a muscarinic receptor agonist (oxotremorine; 1 mum), and blunted by M

223 late the extrinsic pathway with proapoptotic receptor agonists (PARAs) have been disappointing, despi

224 Alternatively, retinoid X receptor agonists partially restored myelin debris phago

225 at MetS confers vascular resistance to GLP-1 receptor agonists, partially through impaired cellular s

226 treatment with either insulin or the insulin receptor agonist peptide S597.

227 suggest cardioprotective properties of GLP-1 receptor agonists, perhaps partially mediated by improve

228 limited to medications (e.g., the muscarinic receptor agonists pilocarpine and cevimeline) that induc

229 are limited to medications (e.g., muscarinic receptor agonists: pilocarpine and cevimeline) that indu

230 ive EP2 agonist and, to a lesser extent, EP4 receptor agonist potentiated LPS-induced IL-33 generatio

231 e shown that glucagon-like peptide 1 (GLP-1) receptor agonists prevent beta-cell loss.

232 The preferential serotonin (5-HT) 2A/1A receptor agonist, psilocybin (Psi), reduces the processi

233 The D2-like receptor agonist quinpirole mimicked this repertoire of

234 The selective GABAB receptor agonist R-baclofen previously reversed social d

235 agonist, SKF38393, and the H2 histaminergic receptor agonist, ranitidine, also hindered recognition

236 A (l-3,4-dihydroxyphenylalanine) or dopamine receptor agonists reduced the number of histaminergic ne

237 trahydrocannabinol and other CB1 orthosteric receptor agonists remain limited because of psychoactive

238 Eltrombopag (ELT) is a thrombopoietin receptor agonist reported to decrease labile iron in leu

239 Mu-opioid receptor agonists represent mainstays of pain management

240 safety profile to currently available GLP-1 receptor agonists, representing a potential treatment op

241 nist alone or concurrently with somatostatin receptor agonists represents a potential therapeutic app

242 Retinoid receptor agonists reversed this phenotype, partly by ind

243 nancy while on treatment with thrombopoietin receptor agonists, rituximab, or mycophenylate, which po

244 tor) and pergolide (a dopamine and serotonin receptor agonist) robustly reduced alcohol intake and BA

245 The thrombopoietin receptor agonist romiplostim could be an effective treat

246 ghest with peroxisome proliferator-activated receptor agonists (RR 1.42, 95% CI 1.15-1.76; six trials

247 ycemia induced by treatment with the insulin receptor agonist S961 increased Deaf1-Var1 and Ptbp2, bu

248 phasic dopamine release by the kappa-opioid receptor agonist, salvinorin A, supporting a selective e

249 Adiponectin receptor agonists, selective peroxisome proliferator-act

250 Type 1 mGluR5 activation increases TRPA1 receptor agonist sensitivity in an AKA-dependent manner.

251 of plasma ApoM/S1P or treatment with an S1P1 receptor agonist (SEW2871) rapidly reversed the vascular

252 Intra-CA1 injections of selective H1 and H2 receptor agonists showed that histamine exerted its effe

253 application of ramelteon, a potent melatonin receptor agonist, significantly decreased firing rate an

254 Dexamethasone (DEX), a specific GC receptor agonist, significantly reduced CCR9-mediated ch

255 d in DRD mice in response to the D1-dopamine receptor agonist SKF 81297.

256 ptor antagonist, timolol, the D1/D5 dopamine receptor agonist, SKF38393, and the H2 histaminergic rec

257 A high-internalizing delta opioid receptor agonist (SNC80) preferentially recruited arrest

258 of the lipid mediator and G protein-coupled receptor agonist sphingosine-1-phosphate (S1P).

259 Dual-acting glucagon-like peptide-1/glucagon receptor agonists such as G49 represent a novel therapeu

260 In Caenorhabditis elegans, opioid receptor agonists, such as morphine, mimic serotonin, an

261 n were rectified by administration of a TrkB receptor agonist, suggesting reduced BDNF-TrkB signaling

262 In Caenorhabditis elegans, opioid receptor agonists suppress the overall withdrawal from n

263 previous 5-HT2C agonists with the melatonin receptor agonist tasimelteon and the putative biological

264 Psilocybin is a serotonin receptor agonist that occurs naturally in some mushroom

265 thylamide (LSD) is a non-selective serotonin-receptor agonist that was first synthesized in 1938 and

266 immunosuppressant therapy and thrombopoietin-receptor agonists that lasted for a median of 15 months

267 t the reported insulin-like actions of GLP-1 receptor agonists that occur independently of the GLP-1

268 of a new series of potent non-prostanoid IP receptor agonists that showed oral efficacy in the rat m

269 a therapeutic strategy to deliver nucleotide receptor agonists to effectively rehydrate the ASL of CF

270 Because of the ability of S1P1 receptor agonists to suppress lymphocyte egress, they ha

271 ullary thyroid cancer reported between GLP-1 receptor agonist treatment and placebo.

272 Compared with placebo, GLP-1 receptor agonist treatment showed a significant 10% rela

273 Combining D2 receptor agonist treatment with rM3Ds-dSPN stimulation r

274 Bath application of the kappa opioid receptor agonist U69593 decreased D2-receptor activation

275 brane-bound, whereas 74% +/- 3% of the total receptor agonist uptake was internalized.

276 Salmeterol is a long-acting beta2-adrenergic receptor agonist used to treat chronic obstructive pulmo

277 The Y2 receptor agonist was unstable in blood, while the dual p

278 production in response to purified Toll-like receptor agonists was also impaired.

279 No significant effect of GLP-1 receptor agonists was identified on fatal and non-fatal

280 Exendin-4 (Ex-4), a GLP-1 receptor agonist, was then fused to the engineered stalk

281 Thus, we examined the effects of a 5-HT2C receptor agonist, WAY163909, and a 5-HT2A receptor antag

282 n added to metformin and sulfonylurea, GLP-1 receptor agonists were associated with the lowest odds o

283 r trials of cardiovascular outcomes of GLP-1 receptor agonists were identified: ELIXA (lixisenatide),

284 GES-1-null and WT bmMFs, whereas EP1 and EP3 receptor agonists were inactive.

285 eurons, the effects of dopamine and dopamine receptor agonists were tested on the capsaicin-activated

286 e statement: Clonidine, an alpha2-adrenergic receptor agonist, which decreases the level of noradrena

287 ancer taking abiraterone, and is an androgen receptor agonist, which promotes prostate cancer progres

288 mice could be rescued by an aryl hydrocarbon receptor agonist, which was sufficient to restore IL-22

289 h problems in diabetic patients, D1 dopamine receptor agonists, which are already in clinical use for

290 e avoided with glucagon-like peptide (GLP)-1 receptor agonists, which are expensive and require daily

291 glucagon-like peptide-1 (GLP-1) or by GLP-1 receptor agonists, which improve glucose homeostasis.

292 administered DL-isoproterenol, an adrenergic receptor agonist whose skeleton includes 1,2-dihydroxybe

293 ration (SA), using the synthetic cannabinoid receptor agonist WIN55,212-2 (WIN), in order to assess m

294 venously self-administer the cannabinoid CB1-receptor agonist WIN55,212-2.

295 Paradoxically, the nonselective CB1/CB2 receptor agonist WIN55212 inhibited GABAergic mIPSCs in

296 o be a remarkably potent and efficacious CB1 receptor agonist with relatively fast onset/offset of ac

297 In search of GLP-2 receptor agonists with better pharmacokinetic characteri

298 r a 3-hour infusion of fenoldopam, a D1-like receptor agonist, with and without pretreatment with ena

299 nd (+)-22a was identified as a potent 5-HT2C receptor agonist, with good selectivity against the 5-HT

300 P2 receptors, whereas the two selective S1P1 receptor agonists (Z,Z)-5-(3-chloro-4-[(2R)-2,3-dihydrox