ライフサイエンスコーパス: receptor antagonist

1 phy was performed with [(3)H]MK-3207 (a CGRP receptor antagonist).

2 gnaling pathway rather than as a competitive receptor antagonist.

3 ory bulb with a broad-spectrum noradrenergic receptor antagonist.

4 ione peroxidase 1 mice with an interleukin-1 receptor antagonist.

5 RP pathway was shown in skin by using a CGRP receptor antagonist.

6 es, such as interleukin (IL)-10 and the IL-1 receptor antagonist.

7 nd the tone change were prevented by an NMDA receptor antagonist.

8 her a D1 dopamine receptor or NMDA glutamate receptor antagonist.

9 effects of LSD are fully blocked by a 5-HT2A receptor antagonist.

10 free media or in the presence of an estrogen receptor antagonist.

11 intranasal corticosteroid over a leukotriene receptor antagonist.

12 with either a glial toxin or an adenosine A1 receptor antagonist.

13 neurons that could be blocked by a nicotinic receptor antagonist.

14 clinical trials of anifrolumab, a type I IFN-receptor antagonist.

15 he presence of 4 mum SCH23390, a dopamine D1 receptor antagonist.

16 a novel anti-angiogenic small-molecule CysLT receptor antagonist.

17 kedly ameliorated by treatment with a CysLT1 receptor antagonist.

18 nted by icatibant, a clinically available B2 receptor antagonist.

19 following administration of a dopamine D2/3 receptor antagonist.

20 3 potentiation was also blocked by ryanodine receptor antagonist.

21 ch was partially rescued by VPC23109, an S1P receptor antagonist.

22 decreased by addition of C1-inhibitor or B1 receptor-antagonist.

23 hymocyte globulin (r-ATG), and interleukin-2 receptor-antagonist.

24 ockers, beta-blockers, and mineralocorticoid-receptor antagonists.

25 l-4-carboxamide derivatives developed as CB1 receptor antagonists.

26 sisted in the presence of glutamate and GABA receptor antagonists.

27 al effects that are unaffected by endothelin receptor antagonists.

28 tor antagonist CGS15943, but not by A1 or A3 receptor antagonists.

29 use it was abolished by ionotropic glutamate receptor antagonists.

30 epression-like symptoms, than other dopamine receptor antagonists.

31 generate more potent, selective melanocortin receptor antagonists.

32 neuron stimulation and resistant to dopamine receptor antagonists.

33 ventrolateral medulla (RVLM) using selective receptor antagonists.

34 heir use in preparing potential kappa opioid receptor antagonists.

35 , long-acting beta-agonists, and leukotriene receptor antagonists.

36 ment associated with non-TARP-dependent AMPA receptor antagonists.

37 playing low internalization, as expected for receptor antagonists.

38 neffective by either nicotinic or muscarinic receptor antagonists.

39 ol drinking, and its sensitivity to dopamine receptor antagonists.

40 d for the development of adenosine human (h) receptor antagonists.

41 n was stratified by baseline use of dopamine receptor antagonists.

42 es is blocked by AM251, a cannabinoid type 1 receptors antagonist.

43 udy of the broad-acting ionotropic glutamate receptor antagonist 1a.

44 herally restricted, potent, competitive NMDA receptor antagonist 1l by a structure-activity study of

45 pective phase I/II study to evaluate the sst receptor antagonist (68)Ga-OPS202 ((68)Ga-NODAGA-JR11; N

46 ro pharmacological characterization of 5-HT6 receptor antagonist 7 indicates high affinity and select

47 th augmented concentrations of interleukin-1 receptor antagonist, a key anti-inflammatory protein.

48 mpounds include selective serotonin (5-HT)2C receptor antagonists, a 5-HT4 receptor agonist, a 5-HT7

49 r agonist, a 5-HT7 receptor antagonist, NMDA receptor antagonists, a TREK-1 receptor antagonist, mGlu

50 ion was found for current use of histamine-2-receptor antagonists (adjusted OR, 1.82; 95% CI, 0.89-3.

51 Mineralocorticoid receptor antagonists administered at high doses may reli

52 effects of PGE2-G were prevented by EP1/EP2 receptor antagonist AH-6809 but not the EP4 antagonist O

53 The FP receptor antagonist AL8810 attenuated the PVAT-induced c

54 onism of orexin receptors with a dual orexin receptor antagonist, almorexant, normalizes the augmente

55 terneurons or locally introducing DA or GABA receptor antagonists alters kinship preference.

56 bo or a single low dose (50 mg) of the D2/D3 receptor antagonist amisulpride, which is believed to in

57 st cancer, we demonstrate here that the IL-1 receptor antagonist anakinra abrogates IL-22 production

58 n acute-phase hsCRP production with the IL-1 receptor antagonist anakinra and the IL-6 receptor block

59 ory effect on IL-1beta secretion by the IL-1 receptor antagonist anakinra in phagocytes of patients w

60 that administration of IL-1 (interleukin-1) receptor antagonist (anakinra) could inhibit the inflamm

61 eved a complete response to recombinant IL-1 receptor antagonist (anakinra).

62 Furthermore, administration of the IL-1beta receptor antagonist, anakinra, efficiently decreased nit

63 Pretreatment with a 5-HT2A receptor antagonist and a 5-HT2C receptor agonist attenu

64 n inverse relationship between interleukin 1 receptor antagonist and colony-stimulating factor 1, col

65 The summation was amplified by a D2-like receptor antagonist and experiments with mice with targe

66 nflammatory markers (increased interleukin-1 receptor antagonist and lower monocyte and neutrophil re

67 emmed from the upregulation of interleukin-1 receptor antagonist and suppression of MDSC-promoting cy

68 5-HT receptor antagonists and agonists were given as drug pre

69 ents in PRRT include the use of somatostatin receptor antagonists and alpha-emitting radionuclides, w

70 l effects of ketamine were abolished by AMPA receptor antagonists and mimicked by the AMPA-positive a

71 cells with two different neurokinin-1 (NK-1) receptor antagonists and siRNA inhibits TNF secretion by

72 ide formulations, mTOR inhibitors, and GLP-1 receptor antagonists) and surgical therapies (eg, laparo

73 g [(11)C]raclopride (a weak competitive D2/3 receptor antagonist), and dopamine release using [(11)C]

74 Losartan, an AT1 receptor antagonist, and inhibitors of either mitogen-ac

75 (ARBs), beta blockers, and mineralocorticoid receptor antagonists, and advanced device therapies.

76 ion immunosuppression was with interleukin-2 receptor antagonists, and antithymocyte globulin in high

77 ed corticosteroids (ICSs), daily leukotriene receptor antagonists, and as-needed ICS treatment coadmi

78 hen cells were treated with the neurokinin 1 receptor antagonist aprepitant before SP stimulation.

79 zed trial of the ability of the neurokinin-1 receptor antagonist aprepitant to reduce symptoms in pat

80 oint because numerous metabotropic glutamate receptor antagonists are available, many of which have b

81 Traditionally, G protein-coupled receptor antagonists are classified as competitive or no

82 Ionotropic glutamate receptor antagonists are valuable tool compounds for stu

83 nd support the further investigation of NMDA receptor antagonists as a possible PTHS treatment.

84 inophen metabolite AM 404 and of cannabinoid receptor antagonists as well as data from tissue-specifi

85 ed telmisartan, a widely used angiotensin II receptor antagonist, as a potent inhibitor.

86 ne and its potential interactions with P2Y12 receptor antagonists, as well as on the central issue of

87 se, early treatment of adenosine diphosphate receptor antagonists at presentation, older age, female

88 Here, we show that the muscarinic receptor antagonist, atropine, eliminated the effect of

89 Type 2 and 3 serotonin receptor antagonists attenuated serotonin's potentiation

90 Therefore, we developed and optimized P2Y4 receptor antagonists based on an anthraquinone scaffold.

91 Unilateral injections of the sigma receptor antagonist BD-1063 prior to METH administration

92 covery of potent and selective adenosine A2A receptor antagonists bearing substituted 1-methylcyclohe

93 cktail of WAY100635 plus GR127935 (5-HT1A/1B receptor antagonists), betaxolol plus ICI-118 551 (beta1

94 The NPY Y1 receptor antagonist BIBO3304 completely abolished NPY ef

95 This effect was blocked by the Y1 receptor antagonist BIBO3304 trifluoroacetate (2 nmol/2

96 ther analyzed the response of NS to the GABA receptor antagonist bicuculline.

97 acetate (2 nmol/2 microl), but not by the Y2 receptor antagonist BIIE0246 (2 nmol/2 microl).

98 cant neutrophil chemotactic effect, and a B1 receptor antagonist blocked this effect.

99 Estrogen receptor antagonists blocked the synergistic increase in

100 A receptor antagonist, or CGP 35348, a GABAB receptor antagonist, blocked the antinociceptive activit

101 or, which was dose-dependently blocked by DA receptor antagonists, but enhanced by cocaine.

102 design of subunit-selective competitive NMDA receptor antagonists by identifying a cavity for ligand

103 To do so, we infused a selective GABAB(1a) receptor antagonist, CGP 36216, intracerebroventricularl

104 longer detectable in the presence of a GABAb receptor antagonist CGP52432.

105 This effect was prevented by a pan-adenosine receptor antagonist CGS15943, but not by A1 or A3 recept

106 Consistently, the histamine receptor antagonist chlorpheniramine potently inhibited

107 gainst NLRP3, recombinant IL-1beta, and IL-1 receptor antagonist confirmed the role of NLRP3 inflamma

108 There are currently numerous NMDA receptor antagonists containing a variety of chemical gr

109 cells, which was blocked by NMDA and mGluR1 receptor antagonists, converting mitral cell responses t

110 This process is inhibited by chemokine receptor antagonists (CoRAs) that block Env-receptor int

111 eatment of non-obese diabetic mice with a Y1 receptor antagonist delays the onset of diabetes.

112 1 receptor antagonist losartan, the oxytocin receptor antagonist desGly-NH2 , d(CH2 )5 [D-Tyr(2) ,Thr

113 increase in social behaviors, while a 5-HT1A receptor antagonist did not alter affiliative vocalizati

114 GABA or glutamate receptor antagonists did not block the ethanol effect.

115 reatment with naloxone, non-selective opioid receptor antagonist, did not affect the effect of l-THP.

116 5, 10, or 15 mg/kg), a nonspecific adenosine receptor antagonist, dose-dependently and at high doses

117 previously reported that memantine, an NMDA receptor antagonist, enhanced two biomarkers of early au

118 Importantly, treatment with the GLP-1 receptor antagonist exendin 9-39 abolished the observed

119 ere pretreated with vehicle solution, a PAC1 receptor antagonist (experiment 2), or a PACAP agonist (

120 was blocked by pretreatment with the apelin receptor antagonist, F13A (0 +/- 1 mmHg; P < 0.01).

121 we bilaterally implanted the potent androgen receptor antagonist flutamide in two key brain regions t

122 otherapy; and the addition of a neurokinin 1 receptor antagonist for adults who receive carboplatin a

123 ition and Patient Outcomes (PLATO), Thrombin Receptor Antagonist for Clinical Event Reduction in Acut

124 s of this trial, the first evaluating a CRF1 receptor antagonist for the treatment of PTSD, combined

125 Suvorexant is an orexin receptor antagonist for treatment of insomnia.

126 cation (proton pump inhibitors or histamine2 receptor antagonists for >6 months) or secondary antiref

127 ion of TNF secretion from DCs is reversed by receptor antagonists for EP2 and EP4, indicating PGE2 ac

128 combined with other negative trials of CRF1 receptor antagonists for major depressive disorder, gene

129 erapy (proton pump inhibitors or histamine-2-receptor antagonists) for patients with IPF, in the abse

130 naldemedine, a peripherally acting mu-opioid receptor antagonist, for the treatment of opioid-induced

131 Notably, administration of a ghrelin receptor antagonist further reduced blood glucose levels

132 a fluorinated analogue of G protein-coupled receptor antagonist (GPR91).

133 ction in arteries from males, whereas the TP receptor antagonist GR32191B inhibited the PVAT-induced

134 oke volume) was improved in the neurokinin-1 receptor antagonist group during the first 6 hours of se

135 urther that a selective and potent mu-opioid receptor antagonist (GSK1521498) reduced both alcohol se

136 One-week treatment with a histamine H1 receptor antagonist (H1RA) ameliorated the glucose intol

137 osis in pre-clinical models and histamine H2 receptor antagonist (H2RA) use may improve symptoms in p

138 indications, we examined associations for H2 receptor antagonists (H2RAs) as a secondary aim.

139 sociated with PPIs compared with histamine-2 receptor antagonists (H2RAs) in privately insured adults

140 roton pump inhibitors (PPIs) and histamine-2 receptor antagonists (H2RAs) suppress gastric acid produ

141 roton pump inhibitors (PPIs) and histamine-2 receptor antagonists (H2RAs) suppress gastric acid produ

142 Treatment with estrogen and androgen receptor antagonists had opposite effects on Lep transcr

143 r effect was blocked by the dopamine D2-like receptor antagonist haloperidol.

144 , the compounds behave like the known sigma1 receptor antagonist haloperidol.

145 No selective P2Y4 receptor antagonist has been described so far.

146 Recently, laropiprant, a DP1 receptor antagonist, has been used in combination with n

147 the N-methyl-d-aspartate class of glutamate receptor antagonists have been shown to be effective adj

148 Endothelin receptor antagonists have emerged as a novel treatment f

149 Interestingly, dopamine D1 and D2 receptor antagonists have opposite effects on plasticity

150 ntiemetic agents (serotonin and neurokinin-1 receptor antagonists) have increased efficacy but are ex

151 ketamine, an N-methyl-D-aspartate glutamate receptor antagonist, have not been fully elucidated.

152 PGE2-mediated cervical ripening or (ii) EP2 receptor antagonists, HDAC4 inhibitors, and 15-PGDH acti

153 teric neurons was inhibited by the nicotinic receptor antagonists hexamethonium and dihydro-beta-eryt

154 The B2 receptor antagonist icatibant is approved for treatment

155 en a chlorine atom of the new class of 5-HT6 receptor antagonists identified herein and a backbone ca

156 lly, the NR2B-selective N-methyl-D-aspartate receptor antagonists ifenprodil and CP-101,606 blocked c

157 Here we have shown that a new CXCR4 receptor antagonist IgG1 antibody (PF-06747143) binds st

158 yte production of the natural inhibitor IL-1 receptor antagonist (IL-1Ra) and shifts production towar

159 of IL-1 is tightly regulated by the specific receptor antagonist (IL-1Ra) and the decoy receptor IL-1

160 the anti-inflammatory cytokine interleukin-1 receptor antagonist (IL-1Ra) secretion in LPS-activated

161 s of C-reactive protein (CRP), interleukin-1 receptor antagonist (IL-1Ra), and soluble interleukin-6

162 ntiinflammatory molecules, specifically IL-1 receptor antagonist (IL-1Ra).

163 Mice were treated acutely with an IL-1 receptor antagonist (IL-1Ra; 100 mg/kg, s.c.) or vehicle

164 ukin [IL]-1 beta [IL-1beta], rs1143623; IL-1 receptor antagonist [IL-1ra], rs4251961; IL-10, rs180087

165 We compared sequences of IL-1beta and IL-1 receptor antagonist (IL1RN), which is an IL-1beta homolo

166 added to ICSs with or without a leukotriene receptor antagonist in a phase III trial in adolescent p

167 support clinical efficacy of a bradykinin B2 receptor antagonist in ACE inhibitor-associated angioede

168 nthesis of an A2-subtype selective adenosine receptor antagonist in only two steps.

169 heres and vascular endothelial growth factor receptor antagonist in polystyrene microspheres (PE) + t

170 TRA2P-TIMI 50 (Thrombin Receptor Antagonist in Secondary Prevention of Atherothr

171 so support an expanded role for neurokinin 1 receptor antagonists in patients who are treated with ch

172 ng kinetics is useful for selecting new hCB1 receptor antagonists in the early phases of drug discove

173 ticotropin-releasing factor receptor 1 (CRF1 receptor) antagonist in adult women with PTSD.

174 evaluated the novel compound, ABT-436, a V1b receptor antagonist, in alcohol-dependent participants i

175 amined the role of LOTUS, an endogenous Nogo receptor antagonist, in promoting functional recovery an

176 omy or treating female mice with an estrogen receptor antagonist increased mortality, indicating a pr

177 hetized rats pretreated with intrathecal A2A receptor antagonist injections before mASH (PaO2 = 40-54

178 oral intake of caffeine, a potent adenosine receptor antagonist, interferes with acupuncture analges

179 tial immune markers, including interleukin 1 receptor antagonist, interferon gamma-inducible protein

180 icroinjection of ICI 174,864, a delta-opioid receptor antagonist, into the rVLM of EA-treated CIH rat

181 H3 receptor antagonists/inverse agonists also may be useful

182 y pain, which was antagonized by CB1 and CB2 receptor antagonists/inverse agonists.

183 The endothelin receptor antagonist is among the most effective agents f

184 e with this, we show that gabazine, a GABA-A receptor antagonist, is antihyperalgesic in primed mice

185 injectable formulation of the full mu-opioid receptor antagonist, is effective for the prevention of

186 have such properties-tachykinin neurokinin 3 receptor antagonists-is proposed as a way of reducing ca

187 ntrally available, potent, and specific P2X7 receptor antagonist JNJ-47965567 (30 mg/kg) significantl

188 Nalmefene is a micro and delta opioid receptor antagonist, kappa opioid receptor partial agoni

189 ke partial agonist properties; like the NMDA receptor antagonist ketamine GLYX-13 produces rapid anti

190 -anesthetic dose of the N-methyl-D-aspartate receptor antagonist ketamine may work to correct these n

191 ulfonate) represents the most selective P2Y4 receptor antagonist known to date.

192 Orthosteric beta-adrenergic receptor antagonists, known as beta-blockers, are amongs

193 yr(2) ,Thr(4) ]OVT, the ionotropic glutamate receptor antagonist kynurenate or the GABAA antagonist b

194 of the glia-derived N-methyl-D-aspartic acid receptor antagonist kynurenic acid (KYNA) have consisten

195 ects whereas subeffective doses of the DA D2 receptor antagonist, L-741,626, rescued cocaine's abilit

196 d social anxiety disorder, suggest that CRF1 receptor antagonists lack efficacy as monotherapy agents

197 pretreatment with the angiotensin II type 1 receptor antagonist losartan, the oxytocin receptor anta

198 -type natriuretic peptide, mineralocorticoid receptor antagonists, low voltage, ineligibility for che

199 2C receptor agonist, WAY163909, and a 5-HT2A receptor antagonist, M100907, given alone and in combina

200 agonist, NMDA receptor antagonists, a TREK-1 receptor antagonist, mGluR antagonists and (2R,6R)-HNK.

201 d by bacterial endotoxin LPS or progesterone receptor antagonist mifepristone more often than current

202 artially blocked by the N-methyl-d-aspartate receptor antagonist MK-801.

203 NTERPRETATION: Treatment with a neurokinin 3 receptor antagonist (MLE4901) could be practice changing

204 ed the effectiveness of an oral neurokinin 3 receptor antagonist (MLE4901) on menopausal hot flushes.

205 through infusions of the mGluR7 presynaptic receptor antagonist MMPIP had no effect on performance.

206 While need for receptor antagonist (MRA) MRA after diagnosis suggests t

207 in patients treated with a mineralocorticoid receptor antagonist (MRA).

208 Mineralocorticoid receptor antagonists (MRA) improve outcome in the settin

209 (ARB), beta-blockers (BB), mineralocorticoid receptor antagonists (MRA), and angiotensin receptor-nep

210 lines recommend the use of mineralocorticoid receptor antagonists (MRAs) for selected patients with s

211 The mineralocorticoid receptor antagonists (MRAs) spironolactone and eplerenon

212 roinjected BDNF or the highly selective TrkB receptor antagonist [N2-2-2-oxoazepan-3-yl amino] carbon

213 aloxone, the non-opioid isomer of the opioid receptor antagonist (-)-naloxone, in infection-associate

214 OT coadministered with a mu-opioid receptor antagonist, naloxone, invoked a supralinear enh

215 tagonists, a 5-HT4 receptor agonist, a 5-HT7 receptor antagonist, NMDA receptor antagonists, a TREK-1

216 nistration of OrxA+/-DynA+/-the kappa-opioid receptor antagonist nor-binaltorphimine (NorBNI) under e

217 ng with ecdysone signaling using an ecdysone receptor antagonist or knocking down the ecdysone recept

218 enol were weaned off post-LT, and endothelin receptor antagonist or phosphodiesterase type 5 inhibito

219 e treatment, which was blocked by the sigma1-receptor antagonist or various nitric oxide synthase blo

220 ceptor antagonist), R-propranolol (5-HT1A/1B receptor antagonist), or racemic propranolol in both mal

221 ng N-t-Boc-Met-Leu-Phe, a nonselective AnxA1 receptor antagonist, or by using an anti-AnxA1 neutraliz

222 dministration of either bicuculline, a GABAA receptor antagonist, or CGP 35348, a GABAB receptor anta

223 Acute CeA infusions with the PACAP receptor antagonist PACAP(6-38) blocked chronic constric

224 dicates that radiolabeled somatostatin (sst) receptor antagonists perform better than agonists in det

225 intravenous infusion of the alpha-adrenergic receptor antagonist phentolamine for only 30 min.

226 es of drugs are now available-ie, endothelin receptor antagonists, phosphodiesterase-5 inhibitors, so

227 ine or serotonin, was prevented by the GABAA receptor antagonist picrotoxin.

228 letion, via treatment of mice with the CSF-1 receptor antagonist PLX5622, and abrogated neuronal-micr

229 o-neutralizing Abs and the class A scavenger receptor antagonist polyinosinic acid inhibited phagocyt

230 nercept (TNFalpha inhibitor), anakinra (IL-1 receptor antagonist), prednisone (NFkappaB translocation

231 ine, a nonselective muscarinic acetylcholine receptor antagonist, produces rapid antidepressant effec

232 d that administration of the beta-adrenergic receptor antagonist propranolol before memory retrieval,

233 Anakinra, an IL-1 receptor antagonist protein, inhibited BAL TH2/TH17 cell

234 S-propranolol (beta-adrenergic and 5-HT1A/1B receptor antagonist), R-propranolol (5-HT1A/1B receptor

235 In contrast, the dopamine D2/D3 receptor antagonist raclopride reduced the seeking of ch

236 Application of D-AP5, but not the purinergic receptor antagonist RB2, blocks the NMDA-induced Kir act

237 Macrophage depletion or injection of an IL1 receptor antagonist reduced ileal inflammation in SHIP-n

238 Suvorexant, a dual (OX1/2R) orexin receptor antagonist, reduced cocaine-evoked premature re

239 of GFAP and MMP-9 and a purinergic ATP (P2) receptor antagonist reduction in calcium response identi

240 demonstrate that such specific anti-cytokine receptor antagonists represent a new class of drugs that

241 A mu opioid receptor antagonist restored GABA currents in D2-, but n

242 Moreover, selective NPY2 and NPY5 receptor antagonists restored vascular integrity and lim

243 Interestingly, 1 mum sulpiride, a D2 receptor antagonist, restored tLTP.

244 mice and in WT mice treated with an insulin receptor antagonist, revealing metabolic control of expr

245 as evidenced by application of glutamatergic receptor antagonists, reversibly inhibiting glutamate-in

246 WIN55212 inhibition was reversed by the CB1 receptor antagonist rimonabant in naive rats but not in

247 Accordingly, local injection of the CB1 receptor antagonist rimonabant into the rostral ventrome

248 Here, we show that the adenosine A1 receptor antagonist rolofylline (KW-3902) is alleviating

249 ndomized Study of the Selective A1 Adenosine Receptor Antagonist Rolofylline for Patients Hospitalize

250 Randomized Study of the Selective Adenosine Receptor Antagonist Rolofylline for Patients Hospitalize

251 Moreover, progesterone receptor antagonist RU-486 partially reversed the effect

252 Progesterone receptor antagonist RU-486 were further applied.

253 However, microinjection of the progesterone receptor antagonist, RU486, into the AVPV reversed the p

254 We used the insulin receptor antagonist S961 to induce severe insulin resist

255 nge or short term treatment with the insulin receptor antagonist S961.

256 Pretreatment with the D1 receptor antagonist SCH-23390 before optical VTA stimula

257 The D1/5 receptor antagonist SCH23390 had no effect on instrument

258 mphetamine seeking, using selective dopamine receptor antagonists (SCH39166 or raclopride) and the Da

259 However, the neurokinin-1 receptor antagonist significantly reduced both circulati

260 eatment of the RVLM with the vasopressin V1a receptor antagonist, SR 49059 (-1 +/- 1 mmHg; 1.1 +/- 1.

261 dyskinesia results from exposure to dopamine receptor antagonists, such as typical and atypical antip

262 effect could also be induced by a nicotinic receptor antagonist, suggesting that xenobiotic exposure

263 l ligation and puncture sepsis (neurokinin-1 receptor antagonist survival = 79% vs vehicle = 54%).

264 A selective TARP gamma-8-dependent AMPA receptor antagonist (TDAA) is an innovative approach to

265 ine (hyoscine) is a muscarinic acetylcholine receptor antagonist that has traditionally been used to

266 s a potent intravenous adenosine diphosphate-receptor antagonist that in the CHAMPION trials reduced

267 Cangrelor is an intravenous ADP receptor antagonist that leads to potent and reversible

268 Leu-NH2 ((68)Ga-RM2) is a synthetic bombesin receptor antagonist that targets gastrin-releasing pepti

269 migraine in humans and the efficacy of CGRP receptor antagonists that evidently do no penetrate the

270 formation for the discovery of adenosine A2A receptor antagonists that have potential to treat multip

271 ull mutations with complete absence of IL-36 receptor antagonist (the two previously unreported mutat

272 As cimetidine is an H2 receptor antagonist, the authors hypothesize that this a

273 tnatal development and investigated two IL-1 receptor antagonists, the competitive inhibitor anakinra

274 ogues, and peripherally restricted mu-opiate receptor antagonists, the latter a major advance in the

275 We then tested TRPV1, EP2, and EP4 receptor antagonists: The EP2 antagonist was the most ef

276 tinal bleeding, and prior use of histamine-2 receptor antagonist therapy (hazard ratio, 1.08; 95% con

277 The P2Y12 receptor antagonist ticagrelor has been shown to be clin

278 Administration of a neurokinin-1-receptor antagonist to block substance P signaling elimi

279 In addition, focal application of GABA receptor antagonists to sensory ganglia triggered or exa

280 ose involving N-methyl-D-aspartate glutamate receptor antagonists, to illustrate principles of networ

281 The oral vasopressin-2 receptor antagonist tolvaptan causes aquaresis in patien

282 ce, >/=60 ml per minute), the vasopressin V2-receptor antagonist tolvaptan slowed the growth in total

283 d after administration of the vasopressin V2 receptor antagonist tolvaptan.

284 n life-long improved visual function in IL-1 receptor antagonist-treated OIR animals.

285 Neurokinin-1 receptor antagonist treatment did not prevent the sepsis

286 on alcohol-related behaviors, and on opioid receptor antagonist treatments, have been inconsistent.

287 expression of a thyroid-stimulating hormone receptor antagonist (TSHAntag), which competitively inhi

288 Vasopressin receptor antagonists, urea, and loop diuretics serve thi

289 sin-converting enzyme inhibitors/angiotensin receptor antagonists, use of beta-blocker, and smoking c

290 uman recombinant form of the endogenous IL-1 receptor antagonist used to treat rheumatoid arthritis,

291 Using RNA silencing and receptor antagonists, we demonstrated that OR51E2 activa

292 pped at least 7 days before the study and H2 receptor antagonists were stopped for at least 24 hours

293 Ketamine is an N-methyl-D-aspartate receptor antagonist, which on administration produces fa

294 zines 4 and 5 were reported to be pan opioid receptor antagonists, while 6 was a MOR agonist.

295 hr-Cys)-dTyr-NH2)), a novel radiolabeled sst receptor antagonist with a high affinity for the sst2 re

296 Ketamine is a potent N-methyl-D-aspartate receptor antagonist with a potentially novel mechanism o

297 to test the hypothesis that a bradykinin B2 receptor antagonist would shorten time-to-resolution fro

298 , and that ketamine (an N-methyl-D-aspartate receptor antagonist) would reduce or block this response

299 ot previously seen for amino acid-based AMPA receptor antagonists, X-ray crystal structures of both e

300 tagonist (antalarmin), and alpha2-adrenergic receptor antagonist (yohimbine; used as a pharmacologica