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1 e suggests ongoing evolution of the ethylene receptor family.
2 tions in synergy with the common-gamma chain receptor family.
3 ted in driving the ligand binding to the LDL receptor family.
4 SorCS3 is a member of the Vps10p-D receptor family.
5 n structural studies of this 7 transmembrane receptor family.
6 pproved targeted inhibitors of the human EGF receptor family.
7 transferred to other members of the Cys loop receptor family.
8 EM-1) is a member of the superimmunoglobulin receptor family.
9 energic receptors from the G-protein coupled receptor family.
10 vivo, which limits our understanding of this receptor family.
11 ious dimer complexes between members of this receptor family.
12 pectrum of human physiology through the 5-HT receptor family.
13 notably the transforming growth factor-beta receptor family.
14 oadly applicable across the eukaryotic pLGIC receptor family.
15 ion of new novel selective agonists for this receptor family.
16 bution is played by members of the chemokine receptor family.
17 RAP-dependent low-density lipoprotein (LDL) receptor family.
18 ity among the more distantly related kainate receptor family.
19 dy receptor interactions within the glucagon receptor family.
20 Fas is a member of the death receptor family.
21 very of antagonists to other members of this receptor family.
22 CD137, a member of the tumor necrosis factor-receptor family.
23 ily mediated by members of the C-type lectin receptor family.
24 racterized members of the cytosolic NOD-like receptor family.
25 ial therapeutic targets within the chemokine/receptor family.
26 ul in implicated diseases for this prevalent receptor family.
27 a role in drug selectivity at this important receptor family.
28 ) not shared by other members of the steroid receptor family.
29 elated protein 1 (LRP1), a member of the LDL receptor family.
30 GPI-anchored protein belonging to the folate receptor family.
31 ght-sensitive versions of the entire GABA(A) receptor family.
32 ost recently identified member of the opioid receptor family.
33 ly unidentified class of tools to study this receptor family.
34 receptor, a member of the G protein-coupled receptor family.
35 ingiomas express members of the somatostatin receptor family.
36 oteins belonging to the TBDR (TonB-Dependent Receptor) family.
37 ns express many drivers of the Gr (Gustatory receptor) family.
38 gh COUP-TFII, a member of the orphan nuclear receptors family.
39 ishing the structural unrelatedness of these receptor families.
40 construction of the phyletic distribution of receptor families.
41 ), muscarinic (M1 and M2), and dopamine (D1) receptor families.
42 uncated receptors in other G protein-coupled receptor families.
43 eptor and repress remaining members of large receptor families.
44 rs of the axon guidance Slit ligand and Robo receptor families.
45 FFA1 (GPR40), a member of G protein-coupling receptor family A, is mediated by medium- and long-chain
49 en the similarities in the mechanism of ErbB receptor family activation, these findings could facilit
50 receptor (PXR), a member of the NR1I nuclear receptor family, acts as a xenobiotic sensor and a param
51 ptor-related protein 1), a member of the LDL receptor family, acts as an endocytic receptor for Bmper
52 aleimide-sensitive factor attachment protein receptor) family, among many others, are organized at th
54 naling, focusing on the class I and class II receptor families and the downstream JAK-STAT pathway al
55 th respect to most members of the prostanoid receptor family and a more modest 30- to 50-fold selecti
57 ember of the cell-adhesion G-protein-coupled receptor family and expressed on postsynaptic Purkinje c
59 mice with deficiencies in the genes of this receptor family and its ligands (protein S(+/-), Gas6(-/
60 through a receptor distinct from the TGFbeta receptor family and known neurotransmitter receptor targ
61 GR, belongs to the class B G-protein-coupled receptor family and plays a key role in glucose homeosta
62 ) is a member of the low density lipoprotein receptor family and plays important roles in a number of
63 olutionary origin of the insect chemosensory receptor family and raise the possibility that their anc
64 ay, which signals through the Frizzled (Fzd) receptor family and several coreceptors, has long been i
65 e several endosomal members of the Toll-like receptor family and several cytosolic sensors for DNA an
66 r (MOR) is a member of the G protein-coupled receptor family and the main target of endogenous opioid
67 F54 can also target proteins of the cytokine receptor family and the mechanism of downregulation invo
68 he parallel discoveries in the C-type lectin receptor family and the Th effector arms of immunity, es
69 d mutations in ionotropic GABA and glutamate receptor families, and discuss implications regarding th
70 po) amplification of Wnt signalling, diverse receptor families, and intracellular and extracellular a
71 most recently identified members of the 5-HT receptor family, and dendritic cells express this recept
72 F21, is a relatively new member of the death receptor family, and it was found that DR6 induces apopt
74 CD40, a member of the tumor necrosis factor receptor family, and its ligand, CD40L (CD154), are impo
75 that depends upon Lrp4, a member of the LDL receptor family, and muscle-specific kinase (MuSK), a re
76 m for members of the steroid nuclear hormone receptor family (androgen receptor, estrogen receptor al
79 ansmitter-gated ion channels of the Cys-loop receptor family are essential mediators of fast neurotra
81 g the many heteromers reported in the opioid receptor family are mu/kappa, kappa/delta, and mu/delta.
83 r, belonging to the Tyro3, Axl and Mer (TAM) receptor family, are expressed in a number of tumor cell
84 ore, we identified LRP1, a member of the LDL receptor family, as a new LeX carrier protein expressed
85 receptors, members of the G protein-coupled receptor family, as molecular targets for this cyclotide
86 reconsider the real functional role for this receptor family, as trafficking partner proteins dynamic
87 that Toll-6 and Toll-7, members of the Toll receptor family best known for functions in innate immun
88 stream of molecularly distinct axon guidance receptor families, but the scope of this overlap is uncl
89 t expression of nine members of the frizzled receptor family by the RBE4 rat brain endothelial cell l
91 ein 5/nucleotide oligomerization domain-like receptor family, caspase activation recruitment domain d
92 , a member of the adhesion G protein-coupled receptor family, cause a human brain malformation called
93 is formed by residues conserved in the 5-HT receptor family, clarifying the family-wide agonist acti
97 an archetype member of the class I cytokine receptor family, comprising receptors with fundamental f
99 we screened cDNAs within the P2Y nucleotide receptor family containing CysLTRs and dicarboxylic acid
100 f the seven-span transmembrane Frizzled (Fz) receptor family controls essential cell fate decisions a
103 g hormone (GnRH) and epidermal growth factor receptor family (ErbB), and gene sets associated with cy
104 have evolved an array of pattern-recognition receptor families essential for recognizing conserved mo
105 ure analysis of other members of the steroid receptor family (estrogen, androgen, and progesterone re
107 man disease and because many members of this receptor family exhibit highly discrete distribution pat
108 e role of the tumor microenvironment on ErbB receptor family expression and found that the status of
110 in 2 (FLRT2), a repulsive ligand of the UNC5 receptor family for neurons, is unexpectedly expressed i
113 trafficking of megalin, a member of the LDL receptor family, from EE to the ERC by coupling it to dy
114 st Spc110, a member of gamma-tubulin complex receptor family (gamma-TuCR), recruits gamma-tubulin com
117 L-36 receptor (IL-36R), a member of the IL-1 receptor family, has been associated with various inflam
118 (TLR3), a member of the pathogen recognition receptor family, has been reported to activate immune re
119 VEM), a member of the tumour-necrosis factor receptor family, has diverse functions, augmenting or in
121 tinuous intracellular trafficking, make this receptor family ideally placed for exploitation by patho
122 tic analysis reveals AMPA, kainate, and NMDA receptor families in insect genomes, suggesting conserve
128 ation, but the role of other members of this receptor family in modulating renal IR injury is unknown
129 evidence that a member of the sex pheromone receptor family in moth species mediates conspecific sex
130 GAS6), a ligand of the TYRO3-AXL-MERTK (TAM) receptor family, in regulating oral mucosal homeostasis.
132 nsects sense odours via several chemosensory receptor families, including the odorant receptors (ORs)
133 g activity of several cytokine/growth factor receptor families, including the TNF-alpha/TNF receptor
134 acellular domains of each member of the IL-1 receptor family, including the IL-36 receptor (also know
136 drive resistance to epidermal growth factor receptor family inhibitors, both in preclinical models a
137 eceptor 4 (MC4R) subtype of the melanocortin receptor family is a target for therapeutics to ameliora
140 hat Axl (one member of the Tyro3, Axl, Mertk receptor family) is a key regulator of antiviral immune
141 rogen receptor (AR), a member of the nuclear receptor family, is a transcription factor involved in p
142 r delta (PPARdelta), a member of the nuclear receptor family, is emerging as a key metabolic regulato
143 rt that Frizzled3 (Fz3), a member of the Wnt receptor family, is essential for maintenance of dividin
144 ), a member of the class A G protein-coupled receptor family, is expressed in brain tissue where agon
147 P) receptor, the fourth member of the opioid receptor family, is involved in many processes common to
148 OP receptor, the fourth member of the opioid receptor family, is involved in pain, drug abuse, and a
149 ell established that EphA7, a member of EphA receptor family, is involved in the topographic mapping
150 ed a novel member of the lipoprotein remnant receptor family known as immunoglobulin-like domain cont
153 teraction with the largest member of the LDL receptor family, low-density lipoprotein receptor-relate
157 we investigated the possibility that the TNF receptor family member CD27 is present on leukemia stem
158 n patients with progressing disease, the TNF receptor family member CD30/TNFRSF8 was confirmed in bio
160 y found that asbestos activates the nod-like receptor family member containing a pyrin domain 3 (NLRP
162 s, we identified the epidermal growth factor receptor family member Erbb3 as a novel GRHL2 target gen
164 TIE2, the glycoprotein TROP2, the small TNF receptor family member FN14, and the G protein-coupled r
165 during IAV infection.IMPORTANCE The NOD-like receptor family member NLRC5 is known to regulate expres
166 inding domain leucine-rich repeat containing receptor family member Nlrp12 in modulating neutrophilic
168 like receptors (TLRs) and interleukin (IL)-1 receptor family member signaling in postnatal gene expre
169 EM5/ADGRA2) is an adhesion G protein-coupled receptor family member that plays a pivotal role in brai
171 rkers, soluble form of ST2 (an interleukin-1 receptor family member), galectin-3, matrix metalloprote
173 th the costimulatory pathways induced by TNF receptor family members (i.e., CD27, OX40, and 4-1BB).
175 y and functional relationships between BILF1 receptor family members from EBV and 12 previously uncha
176 binds LRP1 and other low density lipoprotein receptor family members in the endoplasmic reticulum and
177 m of NF-kappaB-inducing kinase (NIK) and TNF receptor family members including lymphotoxin-beta recep
180 Tregs express several costimulatory TNF receptor family members that activate non-canonical NF-k
181 found to promote localization of other OlfC receptor family members to the plasma membrane in hetero
182 ulated by ligands of IL-1 receptor/Toll-like receptor family members via the activation of NF-kappaB
184 T cell checkpoints, agonists of selected TNF receptor family members, and inhibitors of undesirable c
186 ptor dimer--resembling signalling by insulin receptor family members, which share similar extracellul
187 ival pathways, respectively, by binding Toll receptor family members, which then recruit distinct set
191 de-binding oligomerization domain (NOD)-like receptors family members are key for innate immune recog
192 eceptor belongs to the functional dependence receptor family, members of which share the ability to i
193 -anchored cell-surface receptors of the Nogo Receptor family (NgR1, NgR2, and NgR3) restrict excitato
197 rat podocytes express the protease-activated receptor family of coagulation receptors in vivo High-co
198 ology 2 (LGP2) is a member of the RIG-I-like receptor family of cytoplasmic pattern recognition recep
202 he latter were members of the P2Y purinergic receptor family of G-protein-coupled receptors (P2Y1, P2
205 oid receptor (GR) is a member of the steroid receptor family of ligand-activated transcription factor
207 heterotetramer unprecedented in the nuclear receptor family of ligand-regulated transcription factor
209 gated, prokaryotic homologue of the Cys loop receptor family of neurotransmitter-gated ion channels.
210 o interact with members of the C-type lectin receptor family of pattern recognition proteins, and giv
211 eceptor (NMDAR) is a member of the glutamate receptor family of proteins and is responsible for excit
212 t NOD1 and NOD2, two members of the NOD-like receptor family of PRRs, are important mediators of ER-s
213 y known phosphorylation sites in the steroid receptor family of transcription factors are located in
216 ew family of peptide receptors, the incretin receptor family, overexpressed on many neuroendocrine tu
217 ber of the peptidoglycan pattern recognition receptor family (PGRP-LC), is required for the induction
218 ed caspase-1 activation occurs by a Nod-like receptor family protein 3-independent mechanism because
219 CD30 (TNFRSF8), a tumor necrosis factor receptor family protein, and CD30 variant (CD30v), a lig
221 de-binding oligomerization domain (NOD)-like receptor family pyrin domain containing 12 (NLRP12) play
222 d local tissue hypoxia activate the NOD-like receptor family pyrin domain containing 3 inflammasome.
223 nhibition of the IL-1beta-producing NOD-like receptor family pyrin domain containing 3 inflammasome.
225 opment, where mice deficient in the NOD-like receptor family pyrin domain containing 6 (NLRP6) inflam
226 aims to compare salivary levels of nod-like receptor family pyrin domain containing protein (NLRP) 3
227 nd IL-18, suggesting a role for the NOD-like receptor family pyrin domain containing-3 inflammasome.
228 ed release of IL-1beta dependent on NOD-like receptor family pyrin domain-containing 3 (NLRP3) and AS
229 cleotide-binding oligomerization domain-like receptor family pyrin domain-containing 3 (NLRP3) inflam
231 hich leads to the activation of the NOD-like receptor family pyrin domain-containing protein inflamma
232 monstrate that double deficiency of Nod like receptor family, pyrin domain containing 3 (NLRP3) and c
233 cleotide-binding oligomerization domain-like receptor family, pyrin domain containing 3 (NLRP3) infla
234 tosan, but not chitin, activate the NOD-like receptor family, pyrin domain containing 3 (NLRP3) infla
236 esized that Gal3 is a key to induce NOD-like receptor family, pyrin domain containing 3 (NLRP3) infla
238 ature IL-1beta form depended on the NOD-like receptor family, pyrin domain containing 3 (NLRP3) senso
239 phils express key components of the NOD-like receptor family, pyrin domain containing 3 (NLRP3), and
241 de-binding oligomerization domain (NOD)-like receptor family, pyrin domain containing 3 activation in
242 n the mechanisms tightly regulating NOD-like receptor family, pyrin domain containing 3 activation.
243 g domain leucine-rich repeat-containing-like receptor family, pyrin domain containing 3 and autophago
244 nt, increase in the activity of the NOD-like receptor family, pyrin domain containing 3 inflammasome
246 ng, an early intervention targeting NOD-like receptor family, pyrin domain containing 3 inflammasome
248 idence that the NOD2 target, NLRP3 (NOD-like receptor family, pyrin domain containing 3) is of import
249 g domain leucine-rich repeat-containing-like receptor family, pyrin domain containing 3-associated in
250 o enhanced Caspase-1/Caspase-4- and NOD-like receptor family, pyrin domain containing 3-dependent inf
251 cleotide-binding oligomerization domain-like receptor family, pyrin domain-containing 3 (NLRP3) infla
253 cleotide-binding oligomerization domain-like receptor family, pyrin domain-containing 3 (NLRP3) infla
254 w that bee venom is detected by the NOD-like receptor family, pyrin domain-containing 3 inflammasome
255 cleotide-binding oligomerization domain-like receptor family, pyrin domain-containing 3 inflammasome.
256 nine deiminase 4, and activates the NOD-like receptor family, pyrin domain-containing 3 inflammasome.
257 de-binding oligomerization domain (NOD)-like receptor family, pyrin domain-containing protein 3 (Nlrp
258 RP3 (nucleotide-binding oligomerization-like receptor family, pyrin domain-containing protein 3) acti
259 own to be critical for ligand binding to LDL receptor family receptors, relatively small reductions i
262 glucocorticoid-induced tumor necrosis factor receptor family-related protein (GITR; also called TNFRS
266 2, two members of the intracellular NOD-like receptor family, sense bacterial peptidoglycan-derived f
267 unding members of the intracellular NOD-like receptor family, sense conserved motifs in bacterial pep
270 three different members of the somatostatin receptor family (SSTR) which have natural differences in
272 ic classical HLA class I proteins by diverse receptor families such as the killer cell immunoglobulin
273 ERs or other members of the nuclear hormone receptor family, such as estrogen-related receptor gamma
274 ess is activation of members of the NOD-like receptor family, such as NLRP3, to assemble caspase-1-ac
276 ) is a member of the low-density lipoprotein receptor family that binds multiple ligands and plays a
277 ed allosteric binding site across the opioid receptor family that can accommodate structurally divers
278 ABA binds to members of the PYL/RCAR ABA receptor family that initiate signal transduction inhibi
279 han member of the adhesion G protein-coupled receptor family that is expressed in ECs and is essentia
280 NLRC4 is a cytosolic member of the NOD-like receptor family that is expressed in innate immune cells
281 othelial-specific member of the TGF-beta/BMP receptor family that is inactivated in patients with her
282 Nur77 is an orphan member of the nuclear receptor family that lacks a BH3 domain but nevertheless
283 ceptor belonging to the glycoprotein hormone receptor family that plays an essential role in reproduc
284 or, GPR84, a member of the G protein-coupled receptor family that represents a highly tractable class
285 he complex expression patterns acquired by a receptor family that switched from sensing pathogens ins
286 encodes one of the three members of the IP3-receptors family that form Ca(2+) release channels local
287 ecognition receptors, such as the RIG-I like receptor family, that activate a signaling cascade that
288 female antennae, thus making the ionotropic receptor family the largest of antennae-rich olfactory g
289 ause endogenous bile acids often target both receptor families, the development of selective ligands
293 lecular targeting of epidermal growth factor receptor family, vascular endothelial growth factor rece
294 ound that the ancestor of the entire steroid receptor family was highly specific for estrogens, but i
295 structures of the four members of the opioid receptor family were reported, providing a structural ba
297 Kp44 is a member of the natural cytotoxicity receptor family, which is exclusively expressed on activ
298 oteases as ligands to members of this orphan receptor family while providing new insights into how cy
299 dentified as an actor downstream of multiple receptor families with immunoregulatory functions, inclu
300 ith PYL5 and PYL7 to -10 of the PYL/RCAR ABA receptor family, with PYL7 to -10 interactions being rel
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