ライフサイエンスコーパス: receptor molecule

1 2B and NR2D subunits may be part of a single receptor molecule.

2 nd and distal 3rd intracellular loops of the receptor molecule.

3 min B9-binding pocket of an ancestral folate receptor molecule.

4 resence of these two domains within a single receptor molecule.

5 d to be regulated by sialylation of the CD22 receptor molecule.

6 sensory neurons that express a given odorant receptor molecule.

7 anscription activation are integrated at the receptor molecule.

8 ted sensory neurons express a single sensory receptor molecule.

9 ough it did not require cell surface HS as a receptor molecule.

10 proteins to tyrosine-phosphorylated sites on receptor molecules.

11 the initiation of signaling by many types of receptor molecules.

12 ignaling control when teamed with functional receptor molecules.

13 idence for the close proximity of individual receptor molecules.

14 ber-fibritin proteins targeted to artificial receptor molecules.

15 bind epitopes within one or across two CXCR2 receptor molecules.

16 ducing the homodimerization of two identical receptor molecules.

17 igand binding regions in mutant and chimeric receptor molecules.

18 o-oligomeric ligands binding to and bridging receptor molecules.

19 context of functional chimeric hCCR-5/mCCR-5 receptor molecules.

20 ha induced rapid endocytosis of cell surface receptor molecules.

21 effect by expanding the population of active receptor molecules.

22 uses interact with two putative cell surface receptor molecules.

23 ntaining the basolateral localization of the receptor molecules.

24 volve a binding interaction between CheR and receptor molecules.

25 and kainate receptors at the level of single receptor molecules.

26 posite ends through which it brings together receptor molecules.

27 r-like rotation and self-rotation of the two receptor molecules.

28 ing allosteric coupling of multiple CheA and receptor molecules.

29 tion of serotonin with at least 15 different receptor molecules.

30 , we identify key features of the underlying receptor molecules.

31 naling requires structural studies on intact receptor molecules.

32 creased or polarized expression of toll-like receptor molecules.

33 for CT in PDMS microchips with cell surface receptor molecules.

34 in the expression of G-proteins and odorant receptor molecules.

35 s functionalized with DNA aptamers to act as receptor molecules.

36 mination between surface-exposed and soluble receptor molecules.

37 ng of the extracellular domain of the second receptor molecule after forming the 1ratio1 complex.

38 nteractions, we tested a soluble dodecameric receptor molecule and found that it neutralized primary

39 d using capture HbA1c antibody as a specific receptor molecule and the QD-labeled secondary antibody

40 lasses of odorants via different families of receptor molecules and G-proteins corresponding to the m

41 egrade extracellular matrix and cell surface receptor molecules and have an essential function in mal

42 eceptor changes, causing a dispersion of the receptor molecules and subsequent shrinking of the struc

43 ghly diverse CDR3 loops found in all antigen receptor molecules and suggest that such regions form th

44 receptor subunits, the composition of native receptor molecules and their localization in the brain h

45 interest are the first structures of T cell receptor molecules and, particularly, TCR-ligand complex

46 ormable membrane containing freely diffusing receptors molecules and long repeller molecules that inh

47 tein-1 (LMP1) mimics a constitutively active receptor molecule, and has been shown to activate NF-kap

48 establish hydrophobic interactions with the receptor molecule, and mutations at these hydrophobic re

49 T cell progenitors lacking antigen receptor molecules are also blocked in differentiation a

50 in contact with flat substrates coated with receptor molecules are calculated using a Johnson, Kenda

51 ect C. elegans and that the C. elegans Cry5B receptor molecules are glycolipids.

52 by multiple weak homotypic contacts between receptor molecules are responsible for regulating normal

53 on receptors indirectly only when enzyme and receptor molecules are sterically close, possibly formin

54 ity is encoded within the DEF segment of the receptor molecule, as evidenced by the suppression of a

55 f the total PDGF beta receptor, that not all receptor molecules associated with the E5 protein were t

56 n of a complex and possibly ordered array of receptor molecules at cell contact sites.

57 d by the thymic stroma and the requisite BMP receptor molecules (BMPR-1A, BMPR-1B, BMPR-II), and sign

58 tinal rods signal the activation of a single receptor molecule by a photon.

59 Occupation of the receptor molecule by the ligand (TSH) resulted in a dose

60 -beta receptor, rendering the PDGF type-beta receptor molecule capable of autophosphorylation in resp

61 ce expression of one or all of the candidate receptor molecules (CD81, low-density lipoprotein recept

62 ntibody recognizing the full-length estrogen receptor molecule (clone 6F11), we performed immunohisto

63 ly lower expression of p30/p46 NK-activating receptor molecules compared with those of control subjec

64 ynapses, numerous structural, signaling, and receptor molecules concentrate at the postsynaptic densi

65 Thus, it is possible that a single leptin receptor molecule could have two functional ligand bindi

66 While the ligands sorted to lysosomes, no receptor molecules could be detected there, and no recep

67 n prolactin (hPRL) binds two human prolactin receptor molecules, creating active heterotrimeric compl

68 scale to the absolute logKass values of two receptor molecules, determined independently by direct m

69 V2R- and OR-type receptor molecules do not colocalize in one cell, and on

70 Murine cells lack HIV-1 receptor molecules, do not support efficient viral gene

71 r rotation; phospho-CheB covalently modifies receptor molecules during sensory adaptation.

72 as subsequently discovered that for the same receptor molecule (e.g., the beta-adrenergic receptor),

73 appears to promote a long-lasting change in receptor molecules, either a covalent modification or co

74 alysis revealed that 30% of the photoexcited receptor molecules followed Cycle 1 through the K, M, O,

75 ombined results indicate that the endogenous receptor molecule for AF/R1 fimbriae of RDEC-1 is each i

76 The proteoglycan biglycan is a receptor molecule for flow-resistant adhesion of the bac

77 stent relationship between the affinity of a receptor molecule for its cognate ligand(s) and the spec

78 study, we identify the tetraspanin CD82 as a receptor molecule for the Galalpha1,3-Gal-independent me

79 ell-restricted expression of CD21, the major receptor molecule for the virus.

80 ntry processes, possibly acting as a primary receptor molecule for this virus.

81 N and L-SIGN may represent common attachment receptor molecules for arthropod-borne viruses, (ii) arb

82 The receptor molecules for human and animal hepatitis B viru

83 s relatively immobile with only 28 +/- 1% of receptor molecules free to diffuse with D = (3.64 +/- 0.

84 Our experiments suggest that the Wnt receptor molecule Frizzled7 probably transduces the Wnt6

85 in receptor (IR) that redirects internalized receptor molecules from endosomes to the plasma membrane

86 for binding but also to depletion of the co-receptor molecules from the cell surface.

87 lation involves the trafficking of activated receptor molecules from the plasma membrane, through cla

88 Additionally, it was found for symmetrical receptor molecules from the same compound family that th

89 ansfer of many types of receptor and counter-receptor molecules from the surface of one conjugated ce

90 ges in relative orientations between the two receptor molecules from the transient complex to the 1ra

91 Hitherto, no receptor molecule has been identified that could account

92 matrices and its interaction with a natural receptor molecule has tremendous importance in cell sign

93 Several organelles, receptor molecules, homeostatic processes, and signal tr

94 nt adhesive phage protein has been used as a receptor molecule in biosensing scheme.

95 30 min of insulin treatment, virtually every receptor molecule in this compartment completes at least

96 The conformations of the receptor molecules in all three complexes are very simil

97 is involved in binding to specific host cell receptor molecules in cattle and sheep.

98 n of P. aeruginosa, that it binds to protein receptor molecules in HCEP, that one of the LPS binding

99 in the second intracellular loop of the FMLP receptor molecules in LP patients may play a role in the

100 ion, creates much of the diversity of immune receptor molecules in the adaptive immune system.

101 Individual receptor molecules in the apo form repeatedly sample bot

102 diates an intriguing parallel association of receptor molecules in the crystal lattice.

103 The role of co-receptor molecules in the generation of inducible regula

104 eptor (beta2AR), we observed that individual receptor molecules in the native-like environment of pho

105 band with a ratio of 1:0.9 +/- 0.05 (ligand:receptor molecule) in ligand binding using a Ni column w

106 has the ability to recognize and cleave each receptor molecule independently.

107 ts using chimeric and domain deletion mutant receptor molecules indicate that the amino-terminal D1 d

108 ction of these cytokines with their specific receptor molecules initiates a broad and varied array of

109 The differences among the properties of the receptor molecule interacting with the ligands correlate

110 ) chaperones 11-cis-retinal to convert opsin receptor molecules into photosensitive retinoid pigments

111 Structural studies of cellular receptor molecules involved in immune recognition requir

112 A water-soluble synthetic receptor molecule is capable of selective, controlled en

113 d range of antigens, the number of different receptor molecules is extremely large, resulting in a hu

114 e, equal subsites versus binding to separate receptor molecules is given.

115 of the transporter molecules relative to the receptor molecules is not well delineated.

116 and a threshold number of CD4 and chemokine receptor molecules is required to support virus infectio

117 family of protein tyrosine phosphatase-like receptor molecules (known as IA-2 and PTP-NP/PTP-IAR/IA-

118 A new 1,1'-thiobis(2-naphthoxy)-based receptor molecule (L) containing a benzimidazole moiety

119 Signalling through the cell-surface receptor molecule Notch may regulate oligodendrocyte dif

120 These studies identify CD8 as a PNA receptor molecule on immature thymocytes and show that P

121 We show that the area per receptor molecule on the cantilever surface influences l

122 ability in a gene that specifies tropism for receptor molecules on host Bordetella species.

123 sm determinant), which specifies tropism for receptor molecules on host Bordetella species.

124 dral when they initially bind to one or more receptor molecules on the cell surface, such an interact

125 We immobilized specific receptor molecules on the surface of superparamagnetic b

126 All viruses need to bind to specific receptor molecules on the surface of target cells to ini

127 In cells expressing high numbers of receptor molecules on their surfaces, the SF162-derived

128 rasitic helminths express signal-transducing receptor molecules on their surfaces.

129 Deploying FABP and MPO specific scFvs as receptor molecules onto our high-sensitivity graphene-co

130 e Hedgehog (Hh) signal is transmitted by two receptor molecules, Patched (Ptc) and Smoothened (Smo).

131 Thus, while alpha2M* ligates only one GRP78 receptor molecule per alpha2M*, it may potentially serve

132 erage of approximately 6.2 x 10(5) synthetic receptor molecules per cell surface.

133 ss both a classic multiple membrane-spanning receptor molecule (Pit1) and a second coreceptor or entr

134 Viruses can bind to alternative receptor molecules present on epithelial surfaces and th

135 bition, lantibiotics must recognize specific receptor molecules present on the sensitive bacterial ce

136 on of the HIV envelope with the CD4 and CCR5 receptor molecules present on the surface of target cell

137 Consistent with the idea that soluble receptor molecules provide a trigger for HSV entry, HVEM

138 taneously and competitively to two different receptor molecules, R1 and R2.

139 Only about 30% of receptor molecules recycled back to the cell surface in

140 d gene of Drosophila encodes a transmembrane receptor molecule required for cell polarity decisions i

141 role is to accommodate the millions of light receptor molecules required for efficient photon collect

142 The data suggest that two regions of the EGF receptor molecule, residues 1022-1063 and to a lesser ex

143 sent study, we demonstrate that CXCR1 is the receptor molecule responsible for p17 chemokine-like act

144 n vivo blockade of TNF-alpha using a soluble receptor molecule results in accelerated reendothelializ

145 In such a system, each receptor molecule retains a single on-state and off-stat

146 t be essential to orient the toxin to midgut receptor molecule(s).

147 atory stimuli using a complex arrangement of receptor molecules, signaling cascades, and ion channels

148 ytes to adhere to host endothelial cells via receptor molecules such as ICAM-1 and CD36 is considered

149 utilized to quantitatively detect individual receptor molecules (T-ZZ), map the distribution of recep

150 endoplasmic reticulum (ER) exit sites by the receptor molecule TANGO1/cTAGE5.

151 neurons (ORNs) that express a common odorant receptor molecule target specific glomeruli in the olfac

152 CD122 showed that FLS expressed 4 times more receptor molecules than DF.

153 e CCR5 gene encodes a cell-surface chemokine-receptor molecule that serves as a coreceptor for macrop

154 CCR5 encodes a cell surface chemokine receptor molecule that serves as the principal corecepto

155 e CCR5 gene encodes a cell surface chemokine receptor molecule that serves as the principal corecepto

156 ajor histocompatibility complex (MHC) encode receptor molecules that are responsible for recognition

157 and development of the olfactory system, the receptor molecules that bind odors have not been identif

158 e effectors (TALEs) as the first DNA-binding receptor molecules that provide direct, individual selec

159 pre-Golgi producing highly mobile cytosolic receptor molecules that rapidly accumulate in the nucleu

160 The discovery of these viral substrate receptor molecules that recruit Cul5 through distinct me

161 here we understand some of the signaling and receptor molecules that stimulate and guide cell movemen

162 ship between measures of brain dopamine D(2) receptors (molecules that transmit dopamine signals) and

163 luding increased expression of growth factor receptors, molecules that are involved in tumor invasion

164 While the L1 acts as a receptor molecule, the L2 acts as a control molecule.

165 , while in cells expressing small numbers of receptor molecules, the mutant viruses replicate with ma

166 a cooperative behavior between near-neighbor receptor molecules; the properties of this cooperative p

167 Nonclassical receptor molecules theoretically could act as a type of

168 in which stimulus information travels within receptor molecules through shifts in the dynamic propert

169 Viruses use specific receptor molecules to bind selectively to target cells.

170 We used chimeric hCCR-5-mCCR-5 receptor molecules to examine the functional importance

171 suggested that one Spz cross-links two Toll receptor molecules to form an activated complex.

172 E has been demonstrated by using soluble TNF-receptor molecules to inhibit EAE.

173 l studies of purified recombinant ligand and receptor molecules to investigate the differences in sig

174 parates the intracellular domains of the two receptor molecules to make room for the associated Janus

175 structures over a scale ranging from single receptor molecules to synapses and neurons.

176 sfolded LRP can be re-folded into functional receptor molecules upon Ca2+ restoration.

177 These results indicate that the complex of receptor molecules used by HTLV-3 to bind to primary T l

178 The presence of an oligomeric complex of CCK receptor molecules was confirmed in co-immunoprecipitati

179 witching mechanism to tune the affinity of a receptor molecule, we first generated a set of receptor

180 arch for genes which encode human interferon receptor molecules, we applied the technique of exon tra

181 Using soluble chimeric receptor molecules, we have demonstrated that meningococ

182 he related CD1a, CD1b, CD1c, and neonatal Fc receptor molecules were absent from the surfaces of beta

183 Only 51.5 +/- 7.8% of receptor molecules were found on the plasma membrane in

184 osslinking indicated that most of the cell's receptor molecules were organized in higher-order groups

185 LDL receptor molecules were visualized as elongated, stick-l

186 While GRKs phosphorylate and inactivate receptor molecules which are engaged in G-protein activa

187 In addition, we constructed chimeric receptor molecules which contain the ligand-binding extr

188 ntial postendocytic processing of ligand and receptor molecules, which impacts long-term cell signali

189 s/ml, suggesting that if there is a specific receptor molecule with which the toxin interacts, it is