ライフサイエンスコーパス: recessive lethal

1 ta), contains a large deletion at HY4 and is recessive lethal.

2 f nonessential loci is close to that against recessive lethals.

3 l chromosomes as well as chromosomes bearing recessive lethals.

4 les on the thorax and by several EMS-induced recessive lethals.

5 deleterious mutation in a known carrier of a recessive lethal allele.

6 on and the ability to complement the dU2AF50 recessive lethal allele.

7 In an attempt to identify unknown recessive lethal alleles in the current dairy population

8 e screened for genetic interactions with two recessive lethal alleles of zipper in a second-site nonc

9 o rerio (Cyprinidae), the average numbers of recessive lethal alleles per individual are 1.9 (95% con

10 species, many individuals carry one or more recessive lethal alleles, posing an evolutionary conundr

11 To examine the recessive-lethal alleles in vitro, we devised a novel me

12 Null alleles are recessive lethal and allelic to l(2)31Ek; heteroallelic

13 ns at HY4 and (2) null hy4 alleles that were recessive lethal and contained large HY4 deletions.

14 he second class consists of alleles that are recessive lethal and do not exhibit lethality in combina

15 p53) and Wnt3 on mouse chromosome 11 that is recessive lethal and dominantly marked with a K14-Agouti

16 swm is recessive lethal and is predicted to encode an evolution

17 actosaminyltransferase family (pgant35A) are recessive lethal and result in tracheal tubes that are i

18 Breeding data suggest that H is embryonic recessive lethal and that all harlequins are Hh.

19 This mutation is recessive lethal and was named no turning (nt) because t

20 d showed no cytoskeleton defects, seven were recessive-lethal and three were conditional-lethal and c

21 The remaining two mutations behaved as recessive lethals, and resulted in single-amino-acid sub

22 l mutation at 29 degrees that also acts as a recessive lethal at ambient temperatures.

23 A null PSI mutation is recessive lethal at the first-instar larval stage, and l

24 e of the mutations is a translocation with a recessive lethal breakpoint in cytological region 23C1-2

25 , null mutations in the pnut septin gene are recessive lethal, but homozygous pnut mutants complete e

26 which we identified seven novel multi-allele recessive lethal complementation groups in this region.

27 Homozygous deletions of the Sox70D gene and recessive lethal Dichaete alleles have a variable embryo

28 ustration, we quantify the relative risks of recessive lethal disorders by presenting some simple cal

29 not effect heterodimer formation rescued the recessive lethal dU2AF50 allele.

30 ted in vivo for genetic complementation of a recessive lethal dU2AF50 allele.

31 The recessive lethal effect of Os is due to a mitotic block

32 enesis screens we have recovered a series of recessive lethal emb mutations.

33 we expected, implying an average load of 1.6 recessive-lethal-equivalent loss-of-function (LOF) varia

34 find that one allele in the second class of recessive lethals exhibits dominant-negative behavior, a

35 ars to be best explained by a combination of recessive-lethal gametophytic selection against the part

36 y that allows characterization of effects of recessive lethal genes on adult phenotypes and here enab

37 is search led to the discovery of a putative recessive lethal in Jersey cattle on Bos taurus autosome

38 tion to modify, in embryonic stem cells, the recessive-lethal In(15)21Rk inversion to endow it with a

39 tant half baked (hab), which segregates as a recessive lethal, including alleles expressing zygotic-m

40 A recessive lethal insertional mutation on chromosome 13 h

41 We used the visibly marked, recessive, lethal inversion Rump White (Rw) as a balance

42 a null allele of dU2AF38 is fully penetrant recessive lethal, like null alleles of the Drosophila U2

43 Meckel-Gruber syndrome (MKS) is an autosomal recessive lethal malformation syndrome characterized by

44 Hydrolethalus syndrome (HLS) is an autosomal recessive lethal malformation syndrome characterized by

45 approach, we have identified Hearty (Hty), a recessive lethal mouse mutant with multiple defects, inc

46 zebrafish cardiac function, we isolated the recessive lethal mutant heartstrings, which lacks pector

47 s, we previously isolated two alleles of the recessive lethal mutant no optokinetic response a (noa).

48 Embryonic-recessive lethal mutants have impaired copper homeostasi

49 cribed previously two temperature-sensitive, recessive lethal mutants in Drosophila myb (Dm myb).

50 was originally identified by the analysis of recessive lethal mutants.

51 We focus here on pickwickm171 (pikm171), a recessive lethal mutation discovered in a large-scale ge

52 e for the lethal phenotype and separated the recessive lethal mutation from the P-element by recombin

53 , environment-dependent dominant lethal, and recessive lethal mutation rates.

54 alyronz12 (aln) is a recessive lethal mutation that affects early stages of n

55 Here we describe a recessive lethal mutation, arkadia, generated using gene

56 have led to the isolation of two classes of recessive lethal mutations affecting early dorsoventral

57 in spore viability due to the uncovering of recessive lethal mutations correlated with an increase i

58 We performed genetic screens to isolate recessive lethal mutations in the chromosomal region tha

59 We have used previously characterized recessive lethal mutations in the dynein heavy chain gen

60 Recessive lethal mutations of the lethal(2)giant discs (

61 Finally, heterozygous DmORC2 recessive lethal mutations resulted in a suppression of

62 Zebrafish embryos with the recessive lethal mutations santa (san) and valentine (vt

63 Previous mutagenesis studies identified recessive lethal mutations that were rescued by a genomi

64 dered to be an obligate diploid that carries recessive lethal mutations throughout the genome.

65 Three new recessive lethal mutations, E170A, D194A, and R206A, wer

66 Two new recessive lethal mutations, F256A and Y330A, were identi

67 hila to maintain and analyze stocks carrying recessive lethal mutations.

68 ase domain is shown to complement yeast GUK1 recessive lethal mutations.

69 constructed to analyse the phenotype of the recessive-lethal mutations and used to show that they bl

70 In addition, recessive-lethal mutations that affect residues highly c

71 ue to mildly deleterious alleles rather than recessive lethals or steriles.

72 The recessive lethal phenotype of NPC1a mutants can be parti

73 that is a dominant suppressor with a linked recessive lethal phenotype.

74 insertions analyzed in mice, one-third cause recessive lethal phenotypes affecting various stages of

75 organs caused by an ethylnitrosourea-induced recessive lethal point mutation in the rnpc3 [RNA-bindin

76 In vitro examination of a subset of purified recessive-lethal RNA polymerases revealed that several s

77 and on our ability to independently generate recessive lethal sax mutations, our analysis demonstrate

78 The heart defect (hdf) mouse is a recessive lethal that arose from a transgene insertional

79 that includes the gene for PDGFR alpha, is a recessive lethal that exhibits a dominant pigment phenot

80 Of 13 such mutants, four were recessive-lethal, three were dominant-lethal, and six ha

81 These may include genes that are recessive lethal, vital for development and/or sexually

82 Top3alpha191 is recessive lethal, with most of the homozygous individual

83 A class of recessive lethal zebrafish mutations has been identified