ライフサイエンスコーパス: recombination rate

1 as correlated with local GC content, but not recombination rate.

2 sure favoring the modification of the female recombination rate.

3 lleles and provides a high-resolution map of recombination rate.

4 eps and examine these dips in the context of recombination rate.

5 ocused on the adaptive value of variation in recombination rate.

6 e/absence of variation with gene density and recombination rate.

7 fied associations with empirical measures of recombination rate.

8 he expression level of genes, as well as the recombination rate.

9 e and scope of population-level variation in recombination rate.

10 st variant types show a correlation with the recombination rate.

11 irect correlation between core X binding and recombination rate.

12 rked region- and sex-specific differences in recombination rate.

13 thm, however, increases as the square of the recombination rate.

14 promoters is concomitant with an increase in recombination rate.

15 andidates in regions of high mutation or low recombination rate.

16 levels of recombination, Sir2 represses this recombination rate.

17 been proposed to influence the variation in recombination rate.

18 olution of genetic mapping is limited by the recombination rate.

19 iting in founder animals, and low homologous recombination rates.

20 genes had lower promoter diversity and local recombination rates.

21 r how diffusion and coupling barriers affect recombination rates.

22 duce oxidant levels due to higher OH radical recombination rates.

23 LD information are unlikely to have elevated recombination rates.

24 tionally high mating frequencies and genomic recombination rates.

25 osomal rearrangements and CNVs with elevated recombination rates.

26 ignificant fine-scale heterogeneity of local recombination rates.

27 sequence motif known to associate with human recombination rates.

28 types and showed 10- to 30-fold variation in recombination rates.

29 regions with low methylation levels and high recombination rates.

30 genetic architecture of individual autosomal recombination rates.

31 on longer chromosomes, consistent with lower recombination rates.

32 nt shift in population size and/or effective recombination rates.

33 and that local gene-conversion rates reflect recombination rates.

34 centrated to <5kb regions of highly elevated recombination rates (10-100x the background rate) called

35 th a characteristically high radical-radical recombination rate (2kdim = (1.3 +/- 0.1) x 10(9) M(-1)

36 metrics, linkage disequilibrium statistics, recombination rates, a battery of neutrality tests, and

37 is issue of GENETICS quantifies variation in recombination rate across a small region of the Drosophi

38 and rats reflect a more general reduction in recombination rate across murid rodents.

39 ise nucleotide diversity and divergence with recombination rate across the 20kb intervals, nor any ef

40 cies results in a reduction of the effective recombination rate across the genome.

41 fferentiation was positively associated with recombination rates across chromosomes, with a sharp red

42 hod can accurately estimate the variation in recombination rates across genomic regions.

43 The variation in local recombination rates across the Drosophila genome provide

44 otide diversity, linkage disequilibrium, and recombination rates across the genome.

45 We generated a fine-scale map of recombination rates across two major chromosomes in Dros

46 Is the observed within-species variation in recombination rate adaptive?

47 Recombination rates after CO photolysis were monitored a

48 hoods," where adjacent intervals had similar recombination rates after excluding regions near the cen

49 erall, this genome-enabled map of fine-scale recombination rates allowed us to confirm findings of br

50 ity with other grass genomes correlates with recombination rates along chromosomes.

51 aring the genetic and physical maps to infer recombination rates along the major chromosomes of the D

52 map of SSCX to provide precise estimates of recombination rates along this chromosome and creating a

53 These findings point to clear variation in recombination rate among common laboratory strains, a re

54 The apparent similarity of the variance in recombination rate among individuals between distantly r

55 n hotspots, variation in the average genomic recombination rate among recently diverged taxa has rare

56 Remarkably, MAE genes exhibit an elevated recombination rate and an increased density of hypermuta

57 e current data on intraspecific variation in recombination rate and discuss the molecular and evoluti

58 , questioning whether an association between recombination rate and divergence between species has be

59 y, we found significant correlations between recombination rate and GC content, supporting both GC-bi

60 We study the relationship between recombination rate and gene regulatory domains, defined

61 o a genome-wide negative correlation between recombination rate and genetic differentiation among pop

62 eral explanation for the correlation between recombination rate and genetic variation.

63 onsider in evolutionary analyses relating to recombination rate and highlight the motivations to incr

64 A correlation between recombination rate and intraspecific diversity is in par

65 within species, but no relationship between recombination rate and intron divergence between species

66 ome genetic or genomic factors such as local recombination rate and karyotype may be related to the u

67 Population structure, variation in recombination rate and loci under recent positive select

68 sence of a similar association between local recombination rate and nucleotide divergence between spe

69 has been a strong association between local recombination rate and nucleotide polymorphisms across t

70 The recombination rate and parental allele frequencies in ou

71 Furthermore, recombination rate and recombination hotspots have littl

72 ntreated patients, we estimate the effective recombination rate and the average selection coefficient

73 ether the variation in N(e) is correlated to recombination rate and the density of selected sites in

74 Positive correlation between local recombination rate and the level of nucleotide polymorph

75 methods for inferring parameters such as the recombination rate and the selection coefficient have ge

76 s in the channel, effectively reducing their recombination rate and thus enhancing the performance fo

77 al part of the known correlation between the recombination rate and variant distribution appears to b

78 ies by examining the correlation between the recombination rate and variant landscape within the cont

79 s, levels of pre-existing genetic variation, recombination rates and adaptive landscapes.

80 cal genomic and epigenomic features, such as recombination rates and chromatin dynamics reshaped by i

81 in certain scenarios, such as unsatisfactory recombination rates and deleterious effects on physiolog

82 able inter-individual differences in genomic recombination rates and documented a significant heritab

83 ation, Newick tree output, variable mutation/recombination rates and gene conversion, and efficiently

84 an effect of local genomic features, such as recombination rates and gene densities that reshaped the

85 in Monte Carlo (MCMC) to estimate background recombination rates and hotspots.

86 The additive decreased carrier recombination rates and improved carrier mobility, both

87 in, increased gene density, elevated meiotic recombination rates and in the proximity of repetitive e

88 ocumented a significant relationship between recombination rates and intron nucleotide sequence diver

89 d sites has influenced the relations between recombination rates and patterns of molecular variation

90 c fields to perturb spin precession and thus recombination rates and photoreaction yields, giving ris

91 e that loss of NMD results in an increase in recombination rates and resistance to the DNA damaging a

92 lly, there was a correlation between meiotic recombination rates and targeting frequencies at the tar

93 ich allows us to estimate the spin-dependent recombination rate, and draw parallels with the Majorana

94 about population demography, selection, and recombination rate, and is a key consideration when desi

95 with suppressed re-absorption, reduced Auger recombination rate, and tunable Stokes shift is presente

96 colonies, assuming different mating numbers, recombination rates, and genetic architectures, to asses

97 genomic features (e.g., non-B DNA structure, recombination rates, and histone modifications) in +/-32

98 g imputing missing sequence data, estimating recombination rates, and inferring human colonization hi

99 requently binds promoters, despite their low recombination rates, and it can activate expression of a

100 genome, their preservation in areas with low recombination rates, and their preponderance in highly e

101 to their high color purity, low nonradiative recombination rates, and tunable bandgap.

102 short-circuit current, open-circuit voltage, recombination rates, and variations of the difference be

103 reeds showed that haplotypes associated with recombination rates are both old and globally distribute

104 nd show that the true distinction is whether recombination rates are high or low.

105 However, many recent studies show that recombination rates are often very different even in clo

106 d with identical sequences, we estimate that recombination rates are reduced by 3-fold and by 10- to

107 enteroviruses is associated with cVDPV, the recombination rates are similar for Sabin isolate-Sabin

108 d-state dynamics, with significantly reduced recombination rates as compared to conjugated dimers wit

109 ers such as the (scaled) population size and recombination rate, as well as many aspects of the recom

110 related with local genomic variables such as recombination rate, as well as with signals of recent po

111 this region in the genome, enhanced meiotic recombination rates, as well as other as-of-yet undefine

112 YC-b is located in a gene-rich region with a recombination rate at 3.7 kb per centimorgan, more than

113 The variation of recombination rate at both fine and large scales cannot

114 Additionally, the charge recombination rate at the p-GaInP2/TiO2 interface is gre

115 er polynomials which are used to interpolate recombination rates at all points on the chromosome exce

116 rsion loci relative to the true contemporary recombination rates at the loci but that recombination h

117 onstructing high-resolution maps of relative recombination rates based on the observation of ancestry

118 ue to (i) the reduction in the electron-hole recombination rate because of the reduced dimensions of

119 available for genetic markers, estimates of recombination rate between loci can be combined with LD

120 We uncovered large differences in genomic recombination rate between rodent species, which were in

121 inc finger DNA binding explains variation in recombination rate between species.

122 ciated with the increase and decrease of the recombination rate between them, respectively.

123 ntified both global and local differences in recombination rate between these two closely related spe

124 Using only regions with conserved recombination rates between and within species and accou

125 However, conservation of recombination rates between closely related species has

126 ynonymous/synonymous substitution rates, and recombination rates between HSV-1 glycoproteins and thei

127 es evidence of fine-scale differentiation in recombination rates between populations.

128 we document significant variation in genomic recombination rate both within and between subspecies of

129 ~7.2-cM interval in a region with a moderate recombination rate but outside the least-recombining, pu

130 ators, contributing modestly to estimates of recombination rate but supporting the framework content.

131 l, the point estimation of the corresponding recombination rate by population genetic methods tends t

132 level process can significantly increase the recombination rate (by three orders of magnitude) in agr

133 hin and among dyads, modifiers of the female recombination rate can function as potent suppressors or

134 ctors such as a small population size or low recombination rate can limit the action of natural selec

135 Meiotic recombination rates can vary widely across genomes, with

136 cts the argument that the exceptionally high recombination rates cause a quantitative increase in off

137 s) are suggestive of variation in broadscale recombination rate (centimorgans per megabase) within M.

138 Extreme variation in recombination rates (centimorgans per megabase) was obse

139 nation rate valley" of significantly reduced recombination rate compared to matched control regions.

140 ion performance against advantages of higher recombination rate conferred by intron length.

141 evaluate how and why conflicting patterns of recombination rate conservation and divergence may be ob

142 This in turn reduces the electron/iodine recombination rate constant, which increases the collect

143 e V(oc) hysteresis is not due to a change in recombination rate constant.

144 ted that the theory of the MIF involves four recombination rate constants and an equilibrium constant

145 The relative amplitudes and first-order recombination rate constants of P(f) (0.4-0.6; 40-50 s(-

146 Bimolecular and Auger charge-carrier recombination rate constants strongly correlate with the

147 Their recombination rate constants were identical, indicative

148 ed to extract the singlet and triplet charge recombination rate constants, k(CRS) and k(CRT), respect

149 on by correlating data from (1) and (2) with recombination rate data from a high-resolution genetic l

150 We show that the charge separation and recombination rates decrease exponentially with the shel

151 s data collectively suggest that genome-wide recombination rates decreased gradually, with variation

152 Genomic recombination rate does not affect intra- and inter-colo

153 on can be canceled by a higher electron-hole recombination rate due to the confined space in sphere-s

154 We find that recombination rates estimated by LDhat are biased downwa

155 Recombination rates estimated in F(1) hybrids reveal evi

156 web-based tool that can be used to retrieve recombination rate estimates for single and/or multiple

157 the average proportion of admixture and the recombination rate estimates from the source populations

158 ionally, our method is able to produce local recombination rate estimates.

159 mbination patterns and informing how quickly recombination rates evolve, how changes in recombination

160 When the recombination rate exceeds a certain critical value that

161 s, there is a trend for increased homologous recombination rates, except for the hybrids from one lin

162 When recombination rate fluctuations are included, there is a

163 ed population genetics methods for inferring recombination rates, for detecting selection, and for co

164 he existing procedures of estimating meiotic recombination rates from population genetic data.

165 modeling approach to infer substitution and recombination rates from whole-genome sequences and info

166 her genomic features (promoter polymorphism, recombination rate, gene length, and gene density) are a

167 ic filters, including filters for selection, recombination rate, genetic distance to the nearest gene

168 the field of photocatalysis, the high-charge recombination rate has been the big challenge to photoca

169 ing that the local departures from sex-equal recombination rates have evolved.

170 d "hotspots." Drosophila exhibit substantial recombination rate heterogeneity across their genome, bu

171 The background recombination rates, hotspots, and parameters are evalua

172 xplained 26.2% of the heritable variation in recombination rate in both sexes.

173 is locus has been previously associated with recombination rate in cattle.

174 9/SIX6OS1 was identified that influences the recombination rate in humans.

175 e find that N(e) is positively correlated to recombination rate in one species, Drosophila melanogast

176 , nor any effect of maternal age in weeks on recombination rate in our sample.

177 local gene evolution correlate with the high recombination rate in the 2.8-Mb region with nine-fold h

178 Of interest, the female recombination rate in the 22q11.2 region was about 1.6-1

179 Enhancement of the radiative recombination rate in the presence of Ag-NPs induced LSP

180 light intensities due to a 40% faster charge recombination rate in the S(3) state.

181 out population sizes, natural selection, and recombination rates in ancestral species from applicatio

182 To study the evolution of recombination rates in apes, we developed methodology to

183 Further, we observed that fine-scale recombination rates in D. persimilis are strongly correl

184 pecific scale parameters that allow variable recombination rates in different populations.

185 We measured recombination rates in eight species that collectively r

186 ubstantially disrupt the factors controlling recombination rates in humans.

187 ammalian family and demonstrate that the low recombination rates in laboratory mice and rats reflect

188 ization of crossovers at meiosis to quantify recombination rates in multiple males from each rodent g

189 arrier harvesting efficiencies and increased recombination rates in organic electronic devices.

190 The charge separation and recombination rates in PbS-MB(+) complexes were found to

191 ative explanations for the evolution of high recombination rates in social insects are therefore need

192 of the evolution of multiple mating and high recombination rates in social insects but our results al

193 ds at meiosis I; detect selection for higher recombination rates in the female germ line by the elimi

194 hole transfer rate to the sum of the native recombination rates in the QD.

195 Different recombination rates in various DNA regions (recombinatio

196 We confirm that the recombination rate increases with maternal age, while ho

197 state is long-lived (>1 ns), and the charge recombination rate increases with the number of dissocia

198 Mutation and recombination rates independently associate with nucleot

199 substitutions and positively correlated with recombination rate, indicating widespread linked selecti

200 formed simulations to assess the accuracy of recombination rate inference in the presence of phase er

201 g imputing missing sequence data, estimating recombination rates, inferring human colonization histor

202 type data, imputing missing data, estimating recombination rates, inferring local ancestry in admixed

203 Recombination rate is a key evolutionary parameter that

204 On average, the recombination rate is about 25-45% faster with respect t

205 The population-scaled recombination rate is approximately one-third of the mut

206 When the recombination rate is constant, Kelly's [Formula: see te

207 pected from laboratory experiments, that the recombination rate is higher between closely related org

208 Understanding the causes of variation in recombination rate is important in interpreting and pred

209 However, the recombination rate is known to vary substantially along

210 er, is not extensive, and therefore, the low recombination rate is likely not a major constraint to a

211 ted gene loci (gene-specific sweeps), or the recombination rate is low without interfering genome-wid

212 ithin a 280 kb window, in which the maternal recombination rate is lower than the paternal one.

213 In contrast to the SDR, the maternal PAR recombination rate is much higher than the rates of the

214 Recombination rate is non-uniformly distributed across t

215 widespread pattern of sex differences in the recombination rate is not well understood and has receiv

216 d time scale in MAPbI3/Spiro-OMeTAD, and its recombination rate is similar to that in neat MAPbI3.

217 e demonstrated that the rate of evolution in recombination rate is strongly dependent on the physical

218 al theory calculations in which polaron pair recombination rate is suppressed by resonant exchange in

219 xis or automixis with central fusion and low recombination rates is inferred to be the cytogenetic me

220 Estimating recombination rates is thus of crucial importance for po

221 impact of large tandem repeat arrays on the recombination rate landscape in an avian speciation mode

222 However, the high electron-hole recombination rate limits the yield of highly oxidizing

223 In this study, we constructed fine-scale recombination rate maps for a natural population of the

224 nowledge, the first genome-wide mutation and recombination rate maps for HCMV, we show that genomic d

225 s that genomic instability due to changes in recombination rates may directly contribute to the rate

226 contrast, the mode and tempo of evolution in recombination rates measured on intermediate physical sc

227 With this ABC we infer recombination rate, mutation rate, and recombination tra

228 nic blocks occur in regions with low meiotic recombination rates, no transposable elements, and tight

229 mline transcription, correlates neither with recombination rates nor with the rate of protein evoluti

230 loss of these cells implies a remarkably low recombination rate of photogenerated carriers.

231 the predictions of BSC theory regarding the recombination rate of quasiparticles.

232 e series of polymers, as well as the fastest recombination rate of the charge-separated (CS) species,

233 e low absorption cross-section and ultrafast recombination rates of photoexcited carriers.

234 double-strand breaks can increase homologous recombination rates of single- and double-stranded oligo

235 tum mechanical calculations, including Auger recombination rates, of the quantum-confined Stark effec

236 examined the effect of local GC content and recombination rate on individual variant subtypes and pe

237 xceptionally large (14-Mb) region with a low recombination rate on the X chromosome that appears to h

238 Due to relatively higher recombination rates on smaller chromosomes, larger chrom

239 evidence that germline expression modulates recombination rates or monotonically affects protein evo

240 f individual recombination events and global recombination rate parameters.

241 results predict that rapidly evolving female recombination rates, particularly around centromeres, sh

242 Average recombination rates peak near starts of genes and fall o

243 , possibly mediated by repair processes, and recombination rates, possibly mediated by chromatin and

244 henylene-based systems exhibit slower charge-recombination rates presumably due to reduced electronic

245 ication, which in vivo increased PSII charge recombination rates, producing singlet oxygen and subseq

246 lutionarily conserved elements, and have low recombination rates, reflecting the effects of purifying

247 ns, but simulating longer regions and higher recombination rates remains challenging.

248 The much steeper decrease in charge recombination rate results from a larger hole effective

249 ing data, we estimated the population-scaled recombination rate (rho) and found it to be significantl

250 The genome-wide recombination rate (RR) of a species is often described

251 ffect, sex-linked, site-specific modifier of recombination rate segregating within M. musculus.

252 nce with its role as a modifier of the human recombination rate, SIX6OS1 is essential for the appropr

253 and various evolutionary processes, meiotic recombination rates sometimes vary within species or bet

254 according to the distinct components of the recombination rate, specifically the genetic and physica

255 f many materials: for example, electron-hole recombination rates strongly depend on the character of

256 so found that the number of loci, as well as recombination rates substantially affect ERD.

257 schii chromosomes positively correlates with recombination rates, suggested a cause, and showed that

258 mpared to the human genetic map, broad-scale recombination rates tend to be conserved, but with excep

259 the nanobelts exhibit a lower electron-hole recombination rate than the nanospheres due to the follo

260 In humans, males have lower recombination rates than females over the majority of th

261 The divergence in genomic recombination rate that we document is not proportional

262 nduced enhancement of radiative free carrier recombination rates that lasts even after the removal of

263 long carrier lifetimes and low non-radiative recombination rates, the same physical properties that a

264 -enriched BACs and are characterized by high recombination rates, there are also gene-dense regions w

265 We estimate the population recombination rate to be approximately 0.3 per site per

266 relative contributions of mating number and recombination rate to colony genetic diversity have neve

267 lymorphism data and genome-wide variation in recombination rate to jointly infer the strength and tim

268 from finding disease-risk loci, to inferring recombination rates, to mapping missing contigs in the h

269 itative measurement of charge separation and recombination rates using state of the art computational

270 Our results suggest the existence of a recombination rate valley at regulatory domains and prov

271 This recombination rate valley is most pronounced for gene re

272 Each link type shows a "recombination rate valley" of significantly reduced reco

273 Recombination rate valleys show increased DNA methylatio

274 closely related taxa, whereas genomic-scale recombination rate variation bears a strong signature of

275 an genomic data become available, fine-scale recombination rate variation can be inferred on a genome

276 ally admixed house mice to study patterns of recombination rate variation in a leading mammalian mode

277 e is known about the fine-scale structure of recombination rate variation in D. melanogaster.

278 suggesting a common genetic architecture of recombination rate variation in mammals.

279 tics are preferred when information on local recombination rate variation is available.

280 Our study suggests that recombination rate variation is conserved at broad scale

281 ee text] statistics are more successful when recombination rate variation is controlled for.

282 Accurate assessment of local recombination rate variation is crucial for understandin

283 he first detailed portraits of genomic-scale recombination rate variation within a single mammalian f

284 important concepts such as recombination and recombination rate variation, genome sequencing, and seq

285 ding a human-realistic demographic model and recombination rate variation.

286 el systems, there remains little data on how recombination rate varies at the individual level in nat

287 Meiotic recombination rates vary greatly along the chromosomes,

288 hromosome was 84.61 cM; although the average recombination rate was 0.60 cM/Mb, both cold and hot rec

289 l distances was examined and the genome-wide recombination rate was found to be much smaller than mos

290 The heritability of autosomal recombination rate was low but significant in both sexes

291 g recombination dynamics to distributions of recombination rates, we identified populations of charge

292 other advantage, the electron back transfer (recombination) rates were slower with Cu((II/I))(tmby)2T

293 Loci involved in recombination rate, which is an interesting trait for pl

294 the recovery of the ground state via charge recombination rates, which differ by up to 2 orders of m

295 c islands in general, have exceptionally low recombination rates, which may play a role in their esta

296 Knowledge of the variation in recombination rate will also inform on genomewide patter

297 on in germ cells, we are able to predict the recombination rate with high accuracy.

298 nificant positive associations of fine-scale recombination rate with repetitive element abundance and

299 ific genomic rearrangements and variation in recombination rate within the Z chromosome.

300 virus polymerase, mutation of which reduces recombination rates without altering replication fidelit