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1 of chromosomes and 30 to 50% of genes rarely recombine.
2 tural selection compared to chromosomes that recombine.
3 proper segregation of bivalents that fail to recombine.
4 s and ridges where partial dislocations have recombined.
5 in most tetrads, all three pairs of homologs recombined.
6 ng, to ensure that ectopic sequences are not recombined.
7 e one electron and one hole are captured and recombined.
8 hromosomes are heteromorphic and largely non-recombining.
9 ty dependent rate at which they subsequently recombine (2) to determine the proportion of carriers wh
11 e ability of CRISPR plus rAAV to efficiently recombine a genomic locus and tag it with a selective si
14 purified individually were inactive or when recombined, a co-purified preparation reduced NO in vitr
18 e designed iXora (Identifying crossovers and recombining alleles), a robust method for extracting rel
19 itors and validated kinase potency models to recombine and create "de novo" kinase inhibitor small mo
21 once formed strongly bound CT states rapidly recombine and thus are unlikely to dissociate into free
24 periment revealed that adults differentiated recombined and standard combinations when crossmodal com
25 st electrostatic attractions, prevented from recombining and being transported through the active mat
27 in the level of DNA polymorphism between the recombining and non-recombining regions, and may possibl
28 ype-specific chromosomes nor between the non-recombining and recombining regions, (iii) there is subs
29 (double-negative [DN]) thymocytes, when they recombine, and inaccessible in CD4(+)/CD8(+) (double-pos
30 t overcome the meiotic challenge of pairing, recombining, and segregating more than two sets of chrom
31 alf-antibody exchange' in vivo, resulting in recombined antibodies composed of two different binding
32 cted into mono- to multidomain fragments and recombined as noncognate pairs in vitro, reconstituting
33 of multiple excitons more quickly than they recombine, as well as collection of hot electrons from h
36 meiosis, homologous chromosomes synapse and recombine at sites marked by the binding of the mismatch
37 ion signal (DIS); variants with the same DIS recombined at a higher rate than those with different DI
39 after double-strand DNA cleavage at the two recombining att sites, and that many rounds of subunit r
41 cooling within several picoseconds, but then recombining back to its original 6-fold coordination in
42 may maintain coherent species of frequently recombining bacteria, but the emergence of distinct clus
44 s from four taxonomically diverse clonal and recombining bacteria: Mycobacterium tuberculosis, Staphy
46 none of the intersubtype gp120 recombinants recombined between C1 and gp41 regions either from the F
47 at the 5' end of the noncanonical TRS-B and recombines between nucleotides 5 and 6 of the 8-nucleoti
48 F-beta cytokine signaling, and together with recombining binding protein (RBP)-Jkappa bound the Il9 p
49 ion, gamma-secretase-processed cleavage, and recombining binding protein Jk (RBPj)-mediated downstrea
51 quence), while GATA3(HI) cells had uniformly recombined both Tcrb alleles (one predicting a functiona
53 hat a Gata4-based Cre-activated reporter was recombined by Isl1(Cre) and Nkx2-5(Cre) in a substantial
54 tical inference based on the distribution of recombined carbonaria haplotypes indicates that this tra
55 ize short-carrier-lifetime semiconductors to recombine carriers that cannot contribute to efficient t
59 Comparing the properties of homologously recombined chimeras with one or two crossovers is also a
60 ed skin was progressively repopulated by non-recombined Chk1-expressing cells and ultimately normal s
64 al domain of Int, the resulting chimeric Cre recombines complex higher-order DNA targets comprising >
66 (v) In general, the ability of a sequence to recombine correlated inversely with its methylation stat
67 The GUI allows users to easily import and recombine data, then analyze, visualize, highlight, expo
68 d, at the same time, is able to access novel recombined diversity due to lack of segmental linkage.
70 dogenous homologous recombination systems to recombine DNA in vivo, is a commonly used technique for
71 ghest frequencies of receipt and donation of recombined DNA fragments were observed in non-encapsulat
72 mplex of the tetrameric MuA transposase with recombined DNA must be remodeled to allow subsequent DNA
73 e to identify the presence of the aberrantly recombined DNA sequences, such as those found in the fra
76 ated by short region of homology between the recombining DNA strands that promote joint molecule form
77 of the genes of the species, embedded in low-recombining DNA that is rich in repeats and repressive c
78 denomas almost exclusively contained the non-recombined Dnmt3a allele; no tumors composed of the inac
79 mes (homologs) find their partner, pair, and recombine during meiosis constitutes the central phenome
80 astic domains of the genome that are free to recombine ectopically and experiment with alternative st
81 ygen with formation of a radical couple that recombines either as a peroxide anion 7' to afford the a
82 cleavage roles by forming complexes with the recombining ends to facilitate DNA end processing and li
84 ds in an ordered manner with D to J portions recombining first and then an upstream V joins that reco
85 (3H)-ylidene)ethanal (10), the trans isomers recombined forming the corresponding nitro and nitroso c
88 inct structural and replication modules that recombine frequently and can have different evolutionary
90 olates have shown that multiple genes can be recombined from human, avian, and swine influenza viruse
92 libraries of proteins that were generated by recombining gene fragments from homologous proteins.
93 nuclease, which mediates DNA cleavage at two recombining gene segments and their flanking RAG recogni
94 ase that generates DSBs at the border of two recombining gene segments and their flanking recombinati
95 RAG endonuclease introduces DNA DSBs at two recombining gene segments to form broken DNA coding end
96 rand breaks (DSBs) at the border between two recombining gene segments, generating two hairpin-sealed
98 r knowledge, this is the first time that non-recombining, genic regions as large as 86% of a full chr
101 ch can be generalized to the concept of "non-recombining genomic regions") that are transferred acros
102 tion structure, with a background of unique, recombining genotypes, and the rare occurrence of succes
104 ter the transient induction of Cre activity, recombined GFAP+ stem-like cells and DCX+ neuroblasts we
105 s, associating with the retention of the non-recombined Grp78 floxed alleles in isolated mammary epit
106 g of divergent alternative, dominant and non-recombining haplotypes of an inversion on chromosome 11,
109 t resolution may explain the preservation of recombining, homomorphic sex chromosomes in other lineag
110 dies, based on germline V-gene segments with recombined human regions was used to isolate low-affinit
111 genetic analyses show that noroviruses often recombine in a highly conserved region near the junction
112 f different specificities can dissociate and recombine in bispecific antibodies both in vitro and in
113 rol may be related to its ability to rapidly recombine in critical regions under immune selection pre
120 blished MM and UB progenitor cell lines were recombined in three-dimensional Matrigel implants in SCI
122 CS = 98 +/- 12 ps to give G(+*)-PDI(-*) that recombines in tauCR = 1.2 +/- 0.2 ns, which is >100 time
125 ikely that the two XMRV ancestors could have recombined independently in the wild to generate an infe
126 ulogenesis can be partially recapitulated by recombining individual MM and UB cell lineages, providin
127 memory is the ability to flexibly apply and recombine information from past experience to guide new
133 uring retrieval, these components need to be recombined into one representation, but where exactly su
135 Cxcl12(DsRed) knock-in mice (DsRed-Express2 recombined into the Cxcl12 locus) showed that Cxcl12 was
136 ucleotide segments from multiple alleles are recombined into the expression site to generate a novel
139 ill dissociate to free charges or geminately recombine-is determined at ultrafast times, despite the
141 the coexistence of two genetically diverged, recombining lineages exchanging potentially adaptive mut
143 of bombarded embryos produced calli with the recombined loxP sites under our experimental conditions.
144 ed before the papaya sex chromosomes stopped recombining, making V. monoica a suitable outgroup for i
145 s is the closest system to the ultimate self-recombining material, which can be divided into separate
146 genetic analysis of the processes in the non-recombining mating-type-specific regions of the smut fun
148 ed milk, sterilized milk, UHT fresh milk and recombined milk (UHT milk having milk powder), with 100%
149 ng through NZB and BALB haplotype markers in recombined molecules enabled us to show that in addition
154 Substrates with identical overlap sequences recombined more efficiently than ones with heterologous
155 +*)-FL(3)-PDI(-*) and PTZ(+*)-FL(4)-PDI(-*), recombine much faster from the singlet RP manifold than
157 relative to nuclear genes because of the non-recombining nature of the mitochondrial genome and its p
159 Escherichia coli functions that process the recombining oligo and affect bacteriophage lambda Red-me
161 can influence the repertoire of Vbetas that recombine on alleles containing an assembled VDJCbeta1 g
162 ecombination), precision (V(H) gene segments recombine only to DJ(H) junctions) and allele specificit
163 that GATA3(LO) cells had almost exclusively recombined only one Tcrb locus (that predicted a functio
164 l configuration, while the second allele has recombined only the DJ sequences; the other 40% of cells
166 (2013) show that it is still ongoing in the recombining or pseudoautosomal, regions (PARs) of these
168 istone modifications that correlate with the recombining pair of donor and recipient switch regions.
170 generally dependent on transcription of the recombining partner loci, the c-Myc(+) GC subpopulations
171 eat retrotransposons, which extended the low-recombining pericentromeres and transformed large former
179 transcriptome sequencing), plus 6 genes in a recombining pseudo-autosomal region (PAR) whose genetic
182 ection leads to greater expansion of the non-recombining region and increased Y chromosome divergence
183 some evolution, gradual expansion of the non-recombining region could potentially sometimes occur.
185 name is inherited in the same way as the non-recombining region of the Y chromosome and there should,
188 surprisingly reveal collinearity of the non-recombining regions and although large inversions are en
189 d general method for deletion mapping of non-recombining regions by solving "the travelling salesman
190 s leading to the genetic degeneration of non-recombining regions have mainly been studied in animal a
192 omosomes nor between the non-recombining and recombining regions, (iii) there is substantial populati
193 polymorphism between the recombining and non-recombining regions, and may possibly lead to similar le
194 gous multicopy genes are found in the highly recombining regions, including a large family of protein
198 of GADD45alpha increases methylation of the recombined segment and amplifies the HR-L expressor (hyp
200 acterized by reduced V-J segment distance in recombined sequences, suggesting diminished VL receptor
202 transfer of genetic information between two recombining sequences, and there is evidence that this p
204 the mating-type-specific regions of the non-recombining 'sex chromosomes' and elsewhere in the genom
205 ing methods, facilitates seamless cloning by recombining short end homologies (>/=15 bp) with or with
206 and DprA are required to internalize and to recombine single-stranded (ss) DNA with homologous resid
207 s of strand exchange can be observed, if the recombining sites have nonidentical base pairs at their
209 the emergence of distinct clusters within a recombining species, and the impact of habitat structure
212 ial cleavage takes place and that IntDOT can recombine substrates containing mismatches in the overla
213 abit guanine- and cytosine (GC)-rich, highly recombining subtelomeric regions; low divergence states
214 creating new algorithms and by modifying and recombining successful recipes developed by other player
215 p pathogens were inferred to have frequently recombined, suggesting an epidemic population structure
219 ype mammals, approximately 60% of cells have recombined the DNA of one T cell receptor beta (TCRbeta)
220 he DJ sequences; the other 40% of cells have recombined the V to the DJ segments on both alleles, wit
221 light sensitivity and catalytic activity by recombining the photosensor module of Deinococcus radiod
222 l range of movements could still be achieved recombining the synergies, whereas after incompatible vi
224 grate toward the subcapsular zone where they recombine their TCR beta-chain and gamma-chain gene loci
225 to two parts with different orientations and recombine them after a time evolution of 95 milliseconds
226 example of the utility of these vectors, we recombined them with several Arabidopsis cDNAs encoding
227 e frequency (FF) and biomass burned (BB) and recombined these into a new index to assess fire size (F
230 om alphabeta and gammadeltaTCR gene loci can recombine to confer Ag specificity, thus expanding our u
232 d, optically excited electron-hole pairs can recombine to emit light in a broad frequency comb evenly
233 n atoms bound to molybdenum and sulfur sites recombine to form H2 has a barrier of 22.6 kcal/mol.
234 pathway exists in which two hydroxyl species recombine to generate water and an oxygen adatom, which
235 of H(2) to give two ArGaH(2) fragments which recombine to give the observed product with terminal and
236 their carbon-carbon backbones; the products recombine to nucleate and grow a compact, amorphous lubr
237 loidization, homologous chromosomes pair and recombine to undergo segregation during the first meioti
240 e separated into single-cell populations and recombined to form normal teeth, providing a basis for b
241 om the SPA layer by treatment with urea, and recombined to the SPA layer on the sensor surface for re
242 ies of a given gene, which are then randomly recombined to yield a final library comprising both term
244 scapes from the heme pocket and subsequently recombines to the heme in second-order processes (k = 1.
246 To overcome its sequence dependence, we recombined traits evolved separately in different ribozy
250 bled from these engineered catalytic domains recombine user-defined DNA targets with high specificity
251 alleles at antigen-receptor loci attempt to recombine variable (V), diversity (D), and joining (J) g
252 ple varying sites, emerging from chaotically recombining variation, may be a "signature" of refinemen
255 ing meiosis, homologous chromosomes pair and recombine via repair of programmed DNA double-strand bre
256 ard semiconductor laser, electrons and holes recombine via stimulated emission to emit coherent light
258 Replication and transneuronal transport of recombined virus produced conditional reporter expressio
259 Matter-wave interferometers, which split and recombine wave packets in order to observe interference,
260 igating the ability of flavivirus genomes to recombine, we developed a "recombination trap," which wa
261 ly, the generated inhibiting species rapidly recombine when irradiation with the second wavelength ce
262 ave no corresponding electrons with which to recombine, while in a competing exciton mechanism, the n
263 eria by transformation can site-specifically recombine with bacterial chromosomes in the absence of a
266 grid, driven by their own space charge, they recombine with CR ions reducing their charge state as we
267 is repressed, subtelomeric regions appear to recombine with each other frequently in vegetative cells
269 sis, ecotropic mouse leukemia viruses (MLVs) recombine with nonecotropic endogenous retroviruses (ERV
270 substrate and back-reaction of electrons to recombine with oxidized species on the semiconductor-ele
271 trap states in a range of energies, and then recombine with power law decays that are indicative of c
274 esenchymal-to-epithelial transformation when recombined with control MM, and the isolated Hs2st null
275 Entire repertoires of improved variants were recombined with each other to explore the maximum potent
279 nd shuffled ScFvs in which heavy chains were recombined with light chains from IgE Fabs with specific
280 separation is that objective evidence can be recombined with newly acquired knowledge when a reinterp
284 earrangement in which an upstream VH element recombines with a rearranged VHDHJH joint to generate a
286 pproximately 10 ns, while CdS(+*):ExBox(3+*) recombines with multiple time constants, the longest of
287 y a mechanism in which the substrate radical recombines with superoxide transiently produced in the a
288 ansformed into algae, the substituted genome recombines with the endogenous genome, resulting in a hy
289 is the photodissociation of NO2, which then recombines with the ground electronic state of IMD radic
290 tron remains trapped at the TiO2 surface, it recombines with the hole on a picosecond time scale.
291 atter process was inhibited by tempol, which recombines with the hSOD1-derived tryptophanyl radical,
292 wing evidence for both RNA and ssDNA viruses recombining with host dsDNA genomes and, more surprising
294 es - cells fuse and huge segments of DNA are recombined - with consequences for the spread of adaptat
295 s system was used to estimate the ARG of the recombining X Chromosome of a collection of human popula
296 IMUS that uses mitochondrial (mtDNA) and non-recombining Y chromosome (NRY) haplotypes to eliminate m
297 tive changes may also occur, both on the non-recombining Y chromosome, to shut down expression of mal
298 homologous sex chromosomes, genes on the non-recombining Y chromosomes (and W chromosomes in ZW syste
300 wne and the nonattenuated Toledo strain were recombined, yielding 4 Towne/Toledo chimera vaccines.
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