ライフサイエンスコーパス: redox state

1 h regulates NADP(H) homeostasis and cellular redox state.

2 rriers, which selectively alter the cellular redox state.

3 use the system to quantify the intracellular redox state.

4 direct, compartment-specific manipulation of redox state.

5 nusual additional stabilization of the Cu(I) redox state.

6 of the Fe-S(Met) bond and its dependence on redox state.

7 es NO formation, and is dependent on channel redox state.

8 chrony with metabolism, mediate the cellular redox state.

9 otein homeostasis and the cellular metabolic/redox state.

10 which can potentially maintain the cellular redox state.

11 creased ATP, ADP, NAD(P)H, and mitochondrial redox state.

12 els is coupled to changes in the glutathione redox state.

13 ulfide, and carbon monoxide depending on the redox state.

14 mation by oncogenes that alter intracellular redox state.

15 rphisms in the adiponectin gene and vascular redox state.

16 tors may be involved in sensing the cellular redox state.

17 but differ with respect to the relevant iron redox state.

18 ss requiring tight control of metabolism and redox state.

19 ates in either the Rh2(II,II) or Rh2(II,III) redox state.

20 ransfer reactions, leading to the changes in redox state.

21 ed fluorescent probes that can sense general redox states.

22 single-molecule devices by controlling their redox states.

23 e relative ratio of the two different ligand redox states.

24 A cycle and associated enzymes under varying redox states.

25 -side of the protein in each of the four CcO redox states.

26 cytosolic redox and decreasing mitochondrial redox states.

27 he Cu(Z) site accesses the 2-hole and 1-hole redox states.

28 om 0.5 to 15.4 wt % and different initial Fe redox states.

29 The two redox states 3(*-) and 3(2-) retain the geared alpha and

30 oxidized Ir particle showed exclusively the redox state (+4), the Ir/IrOx/ATO system exhibited evide

31 , ground-state stabilization, and breadth of redox state accessibility), we prepared three electron-t

32 ors, including substrate concentrations, the redox state, activation and inhibition of specific enzym

33 The MOPC redox state, along with measurements of oxygen consumpti

34 ement of the CBPQT(4+) ring in its different redox states among these three potential recognition sit

35 2 in the IMS results in a more reduced Mia40 redox state and a delay in oxidative folding and mitocho

36 -energy azo pi* orbitals in the intermediary redox state and additional stabilization of 2 from struc

37 In the present study, changes in arsenic redox state and binding environment in these experiments

38 ndings demonstrate how SA alterations in the redox state and Ca(2+) homeostasis modulate the inflamma

39 Connections between redox state and complex behavior allow bacteria to link

40 t between experimental quantification of the redox state and device simulation reveals that changes i

41 mitochondria, resulting in altered cytosolic redox state and energy deficiency.

42 erse stimuli such as small molecules, light, redox state and gases.

43 isms, which link cytoskeleton remodeling and redox state and impact epithelial plasticity and myofibr

44 in the ER, maintenance of the ER glutathione redox state and levels likely depends on ER glutathione

45 Tin redox state and local structure were investigated by Sn-

46 ron transport is required to ensure adequate redox state and lumen pH.

47 nfluenced by ecological selection imposed by redox state and mineralogy, possibly due to effects on n

48 al energy production through the NAD(+)/NADH redox state and modulating cellular signaling processes

49 , and (13)C NMR signals as a function of the redox state and molar ratio of added ligand.

50 Reduced levels of proteins regulating redox state and neuronal stress markers, as well as incr

51 y and deliver nitric oxide with a controlled redox state and rate is crucial for its pharmaceutical/m

52 1) of Arabidopsis is a sensor of the plant's redox state and regulates transcription of core circadia

53 the expression of GPX1, which influences the redox state and sensitivity to oxidative stress induced

54 Tin redox state and surface structure were investigated by S

55 ic compounds, which hence impact the aquifer redox state and the carbon fate.

56 (BS) DFT rationalizes the interplay between redox state and the Fe-S and Fe-Fe distances as predomin

57 ciated with Fe oxy/hydroxide depended on the redox state and water content of the biosolids.

58 copper and sulfur, notably by changing their redox state and, as a consequence, their ability to bind

59 e coordinated metal ions in their respective redox states and electrical neutrality, as well as relat

60 Uranium redox states and speciation in magnetite nanoparticles c

61 of N2OR for Cu(Z) and Cu(Z)* poised in these redox states and steady-state turnover assays with diffe

62 lizing "electrolyte gating" to control their redox states and, as a result, their steady-state transi

63 ate-to-pyruvate ratio (a marker of cytosolic redox state) and BMI, suggesting that AT is glycolytic b

64 lar metabolism, including on the metabolome, redox state, and glucose utilization.

65 a previously unrecognized effect on cardiac redox state, and help to refine the design of impending

66 ative phosphorylation programing, a shift in redox state, and high plasticity for metabolic adaptatio

67 ase is finely regulated by the intracellular redox state, and it is inhibited under stress conditions

68 he redox potential of a molecule, change its redox state, and thus allow the manipulation of single m

69 d nitrogen ligands coordinate the Cu in both redox states, and a labile hydroxide ligand is lost upon

70 Rhythmic oscillations in cellular redox state are another universal feature of circadian t

71 nduced changes in immune cell metabolism and redox state are associated with CD4(+) T cell depletion,

72 ations show that changes in the quinone pool redox state are responsible for the apparent inorganic p

73 ibit considerable differences in dynamics of redox states are extracted by statistical machine learni

74 contributions of the three different uranium redox states are quantified with the iterative transform

75 h is the primary determinant of the cellular redox state, are associated with aging and neurodegenera

76 NMDAR function was due in part to an altered redox state as bath application of the reducing agent, d

77 io cholerae H-NOX may act as a sensor of the redox state as well as NO.

78 to the steady-state distributions of enzyme redox states as a function of lipoamide/dihydrolipoamide

79 In treating a population of surface-confined redox states as constituting a density of states, these

80 st, ABA and pyrabactin altered the vitamin C redox state at early stages of fruit development and mor

81 ns during ageing, whereas in the cytosol the redox state becomes more oxidizing with age.

82 ing mitochondrial morphology, transport, and redox state before and after laser axotomy.

83 drogen-bond donor to water539 (W539), the S0 redox state best describes the unusually short O4-OW539

84 mutase 2, leading to a reduced intracellular redox state, blunted oxygen sensing, and impaired caroti

85 ent regulation of HIF-alpha isoforms and the redox state by CIH in the central and peripheral nervous

86 d the improvement of vascular and myocardial redox state by multiple different mechanisms (directly o

87 associated with restoration of intracellular redox state by Nrf2-related regulation of expression of

88 Prdx1, an enzyme that regulates the cellular redox state by reducing hydrogen peroxide to water and o

89 hat more subtle changes in the intracellular redox state can act as signals, eliciting responses with

90 metabolic engineering whereby an undesirable redox state can be exploited to drive desirable metaboli

91 a consecutive series of five, six, and seven redox states can be accessed in the resulting SC.7PF6 (0

92 The altered cellular redox state caused by the loss of Pim occurred as a resu

93 altered redox homeostasis and NAD(H) content/redox state control the phenotype of CI mutants and phot

94 ed metformin-mediated increases in cytosolic redox state, decreases in plasma glucose concentrations,

95 nize the bc1 complex and bind or unbind in a redox state-dependent manner.

96 Thermus thermophilus (TtRp) undergoes modest redox-state-dependent and ligand-dependent conformationa

97 membrane anchor (trunc-TtRp) to investigate redox-state-dependent conformational changes.

98 short-circuit is effectively prevented by a redox-state-dependent organization of water molecules wi

99 Discoveries of redox-state-dependent protein kinase S-glutathionylation

100 , including the maintenance of intracellular redox states, detoxification, and metabolism.

101 Deranged cardiac metabolism and abnormal redox state during cardiac diseases foment arrhythmogeni

102 osits of the Yangtze Sea to assess the ocean redox state during the Early Cambrian metazoan radiation

103 ctive molecules exhibiting either two stable redox states (e.g., ferrocene and quinones) or more than

104 rocene and quinones) or more than two stable redox states (e.g., metalloporphyrins, polyoxometalates,

105 tionally and directly resolves the spread of redox state energies the electrode is communicating with

106 Flux appeared to be regulated by redox state, energy charge, and metabolite concentration

107 nt increase in the heart and liver cytosolic redox state, estimated from the [lactate]:[pyruvate] rat

108 dase 2, leading to an oxidized intracellular redox state, exaggerated hypoxic sensitivity, and cardio

109 endent activation/inhibition and active site redox states for various conditions.

110 the pdt ligand, CrHydA1(pdt), identified two redox states H(pdt)-ox and H(pdt)-"red".

111 Changes in redox state have been shown to influence or trigger chro

112 Different redox states have a profound effect on domain orientatio

113 The Ir(III,III), Ir(IV,IV) and Ir(IV,V) redox states have been computationally studied both with

114 All six of the observable redox states have been identified by electrochemical tec

115 t of residues around heme a changes with the redox state, hence suggesting that the H channel could p

116 lly encoded in vivo sensors reporting on the redox state in an organelle-specific manner, we show in

117 Therefore, the role of apoplastic redox state in controlling aphid infestation was explore

118 The apparent imbalance of cytosolic redox state in Deltaflv3B heterocysts also has a pronoun

119 but its role in the regulation of myocardial redox state in humans is unknown.

120 NAD(+) and NADH contents and the NAD(+)/NADH redox state in intact human brain.

121 mediate of cytochrome c oxidase is the first redox state in its catalytic cycle, where proton transfe

122 ed protocol to image and monitor NAD(+)/NADH redox state in living cells and in vivo using a highly r

123 tween Th2 polarization and alteration of the redox state in LP-BM5 infection is presented.

124 tudying the intracellular NAD metabolism and redox state in normal and diseased human brain or other

125 oss-talk between adipose tissue and vascular redox state in patients with atherosclerosis.

126 ranscription factor undergoes changes in its redox state in response to changing levels of copper or

127 differential roles of NOXs in modulating the redox state in response to different shear stresses, whi

128 salt stress tolerance by regulating the GSH redox state in rice.

129 ence of taurocholate, as compared with their redox state in the absence of taurocholate.

130 were due to differences in slice health, the redox state in the auditory cortex was assessed by measu

131 ge, into the cellular NAD concentrations and redox state in the brains of healthy volunteers.

132 mediated by epigenetic re-programming of the redox state in the CB chemosensory reflex pathway.

133 o describe the involvement of changes in the redox state in the control of DDR-dependent upregulation

134 Likewise, the redox state in the cytosol and the ER change in an oppos

135 plastoquinone (PQ) pool into a more reduced redox state in the dark caused an enhanced LHCII phospho

136 p-ocean oxygenation.The evolution of oceanic redox state in the past is poorly known.

137 We modified redox state in the reference plant, Arabidopsis thaliana

138 he bonding in solid CP 3 involves noninteger redox states in a resonance hybrid repeat unit best form

139 s opportunities for evaluating intracellular redox states in biochemical investigations.

140 pic investigations on purified SH in various redox states in combination with density functional theo

141 Redox states in the auditory cortex of young and aged an

142 ed active enzyme CrHydA1(adt) shows the same redox states in the respective potential range as observ

143 ng the possible role of reduction/oxidation (redox) state in cancer.

144 ving modulations of intra- and extracellular redox states, in combination with other therapies, may l

145 disease stage, all of which affect the thiol redox state, including tHcy.

146 It is a metal that exists in multiple redox states, including the divalent ferrous (Fe(2+)) an

147 Nlrp3(-/-) macrophages presented a protected redox state, increased maximum and reserve oxygen consum

148 lts suggest that alterations in the cellular redox state induced by viral infection are communicated

149 nd elucidation of the mechanisms whereby the redox state influences circadian regulation.

150 yme complexes both copurify with haem, whose redox state influences the activity of the latter.

151 ects of cardiac biology including myocardial redox state, intracellular Ca(2+) cycling, the electroph

152 H2 binding to the Ni-SIa redox state is energetically favored (by 4.0 kcal mol(-1

153 Because competing redox state is known to drive isotopic fractionation, we

154 r quantifying intracellular NAD contents and redox state is limited to a few in vitro or ex vivo assa

155 )] model cluster in its one-hole (S = (1)/2) redox state is thoroughly characterized.

156 oxybutyrate, another metabolite that impacts redox state, is also a strong browning inducer.

157 major antioxidant and indicator of cellular redox state, is increased in unstressed puf3Delta cells

158 ectronic and geometrical features in various redox states, it is established that, depending on wheth

159 conformational forms in two different flavin redox states; (iv) reactivity of the reduced FMN domain

160 through its high sensitivity to the cellular redox state, may play a role in oxidative stress signali

161 Together with previous work indicating that redox state mediates senescent physiology in the hippoca

162 with difficult-to-treat asthma, the cysteine redox state might represent a potential therapeutic targ

163 o yield a thermodynamically constrained four-redox-state model of E3 that simulates pH-dependent acti

164 Quantification of the redox state of 1098 Cys residues using OxICAT revealed t

165 Altering the redox state of a cyclobis(paraquat-p-phenylene) ring sim

166 enorhabditis elegans through controlling the redox state of actin regulators.

167 These data suggest that the redox state of bacteria during infection differs signifi

168 We demonstrate that control over the redox state of BFDMA can be used to influence key physic

169 act as oxidants to balance the intracellular redox state of cells in anoxic biofilm subzones.

170 s assessed by measuring 29 cytokines and the redox state of circulating albumin (HNA2), a marker of s

171 asured Kd values are highly dependent on the redox state of CPR.

172 loss of kinase activity suggesting that the redox state of Cys-246 and Cys-266 is a critical determi

173 arging state of tRNA but is regulated by the redox state of cytochrome c.

174 he steady-state level of ROS, as well as the redox state of each compartment, is different at any giv

175 The redox state of each CXXC motif is presently unknown.

176 thermore, the derivation of the quantitative redox state of each TM in each color shows that the cont

177 The redox state of Earth's convecting mantle, masked by the

178 ed peptides may serve as probes for both the redox state of extracellular cysteines and for assessing

179 Asn378 side chain, that is modulated by the redox state of FAD.

180 rature can also be influenced by varying the redox state of ferrocene in the polymer main chain.

181 By switching the redox state of ferrocenyl units - separately or in a coo

182 al mass transfer calculations to predict the redox state of fluids generated during serpentinite dehy

183 roup of heme a3 and, to a lesser degree, the redox state of heme a and protonation state of Glu286.

184 itochondrial biology, energy metabolism, and redox state of human HFs are subject to profound (neuro-

185 ors the electron transport chain through the redox state of its FAD cofactor.

186 t between 10% and 20% of dissolved P bears a redox state of less than +5 in water samples from centra

187 the current knowledge about melanin and the redox state of melanocytes, how paracrine factors help c

188 lular levels of NADH, thereby modulating the redox state of neurons.

189 These results demonstrate that the redox state of noninnocent Z-ligands can be used to cont

190 rolling a tetrazine ligation by changing the redox state of one of the reactants.

191 quantities large enough to have affected the redox state of P in the ocean.

192 Recently, circadian oscillations in the redox state of peroxiredoxin have been described as an a

193 carboxysomes in the cell correlates with the redox state of photosynthetic electron transport chain.

194 chanism, in which the interdependence of the redox state of QA and the binding by HCO3(-) regulates a

195 vicinity of a nuclear repository control the redox state of radionuclides, which in turn has a strong

196 e examined under conditions that altered the redox state of RyR1.

197 Changes in the redox state of superoxide dismutase 1 (SOD1) are associa

198 The redox state of the "remote" metal (Ni) modulates the hyd

199 rce microscopy (AFM) to demonstrate that the redox state of the [4Fe4S] clusters regulates the abilit

200 The reduced redox state of the active-site copper and not the subseq

201 pe ratios are a sediment paleo proxy for the redox state of the ancient ocean.

202 ovellite NCs is sustained by a change in the redox state of the anion framework.

203 The results presented indicate that the redox state of the apoplast has a profound influence on

204 embled species is actuated upon changing the redox state of the bipyridium units involved in the tect

205 past reports, the catalytically active metal redox state of the catalyst has remained under debate.

206 iosynthesis, as well as in the regulation of redox state of the cell, particularly a set of glutaredo

207 ips1, but this process is independent of the redox state of the chloroplast.

208 o the active site that are controlled by the redox state of the cofactor.

209 osition of the pyridine rings influences the redox state of the complex, governing the distribution o

210 Here we show that both the redox state of the copper-binding cysteines of SCO1 and

211 ry control--control exerted by change in the redox state of the corresponding gene product.

212 lectrochemically switched via control of the redox state of the dye.

213 conditions where we are able to control the redox state of the enzyme precisely.

214 where H2 cleavage takes place on the Ni-SIa redox state of the enzyme, is characterized by very low

215 the nematode Caenorhabditis elegans that the redox state of the ER is subject to profound changes dur

216 one or two molecules of N2 depending on the redox state of the Fe2(mu-H)2 unit.

217 aggregation may be coupled to changes in the redox state of the G93A and A4V mutants upon mild oxidat

218 This effect was caused by an altered redox state of the gamma-subunit under low, but not high

219 egrin clustering, presumably by changing the redox state of the integrin.

220 llular bioenergetics that was related to the redox state of the iron.

221 m chemical calculations demonstrate that the redox state of the ligands determines the switching stat

222 If the redox state of the metal ion is changed from paramagneti

223 mations based on the identity and the formal redox state of the metal.

224 ed the differential roles played by both the redox state of the mNT cluster and dioxygen in cluster t

225 We monitor the redox state of the molecule by tracking its characterist

226 e are no direct data constraining either the redox state of the ocean or marine biological productivi

227 and this interaction is contingent upon the redox state of the OhrR.

228 rchean sulfur deposits used to determine the redox state of the paleoatmosphere.

229 strated by electrochemically controlling the redox state of the pendent diimide unit of the molecule

230 hanism between intermediate metabolites, the redox state of the plastid and the expression and bindin

231 We discovered that PTOX helps control the redox state of the plastoquinone (PQ) pool in these orga

232 Artificial modification of the redox state of the plastoquinone (PQ) pool via 3-(3,4-di

233 ht harvesting complexes II, depending on the redox state of the plastoquinone pool.

234 We further show that the redox state of the PQ pool in etioplasts might control c

235 ur results underline the central role of the redox state of the PQ pool in the light acclimation of d

236 Our results show that the redox state of the PQ pool of Synechocystis sp. strain P

237 The in vivo redox state of the PQ pool was correlated with the resul

238 chael reaction whose kinetics depends on the redox state of the redox polymer catalyst, we show that

239 We found that DsbC regulates the redox state of the single cysteine of the L-arabinose-bi

240 ion of PSI in the mutant correlates with the redox state of the stroma rather than photodamage and th

241 Altering the redox state of the triiron core resulted in significant

242 could not unequivocally ascertain the final redox state of this residue.

243 efenses has been linked to the metabolic and redox states of bacteria.

244 ed by neutral pH, low salinity, and variable redox states of both iron and sulfur species.

245 ts can be related to it, such as: changes in redox states of components of the linear electron transp

246 at distinct rates that are dependent on the redox states of FBD.

247 statics simulations with the protonation and redox states of heme a, a3, Cu(B), Y288, and E286 used t

248 challenged by experimentally accessing both redox states of metalloproteins.

249 ntial (DeltaG(ATP)), membrane potential, and redox states of NADH and cytochromes b(H), b(L), c(1), c

250 F-MS is a suitable separation method for the redox states of Pu, Np, and Fe.

251 roximately 5 ps, which leads to a mixture of redox states of the acceptor ligand.

252 ee-state mechanism that represents the major redox states of the enzyme and includes a detailed repre

253 dA to 1.98 A resolution and those of several redox states of the enzyme to different resolutions.

254 (-) ligands of the (2FeH) site for different redox states of the H-cluster.

255 wo additional complexes presenting different redox states of the ligand framework.

256 Several redox states of the octairon cluster are accessible, as

257 xperimental and computational studies of the redox states of these oligo(alkylfuran)s reveal that 16F

258 ectroscopies have been used to determine the redox states of these sites under different reductant co

259 y induce changes in the reduction/oxidation (redox) state of the photosynthetic electron chain that a

260 hat allowed us to monitor alterations in the redox-state of epithelial cells at different stages of m

261 he most simple and basic way of altering the redox-states of organic molecules.

262 on donating capacities (EDCs), and hence the redox states, of three different types of DOM during oxi

263 ny structural change that could affect their redox state, oligomeric structure, and/or interaction wi

264 could be used in the study of the effect of redox states on living systems, and lead to clinical pho

265 t it requires an oxidising shift in the cell redox state or the generation of reactive oxygen species

266 The redox state, organic complexation, and phase (dissolved

267 l (2AG), is tightly controlled by the cell's redox state: oxidative signals such as hydrogen peroxide

268 Based on the lipoate redox state, PfLipL1 either functions as a canonical lip

269 ignals derived from perturbations in plastid redox state, plastid gene expression, and tetrapyrrole b

270 transitions of 2-Cys peroxiredoxins such as redox state, post-translational modifications, and pH.

271 edox-active molecules often display multiple redox states, precise control of a molecule's redox pote

272 A highly oxidized cysteine redox state promotes a posttranslational modification of

273 nhibited respiration and reduced the NAD(P)H redox state, pyridine nucleotide redox states were unaff

274 nase, resulting in an altered hepatocellular redox state, reduced conversion of lactate and glycerol

275 change in the energy level alignment of the redox states relative to the Fermi level of the electrod

276 Rescue of the redox state restored responsiveness to TNF-alpha in KRIT

277 it of stoichiometric control over the ligand redox states resulted in synthesis of the reduced framew

278 t with a previously inferred shift in marine redox states, severe perturbations to Earth's climate sy

279 ht maintained PSI and PSII in a more reduced redox state, showed greater regulated nonphotochemical e

280 ) appear to reflect alterations in the serum redox state that resulted in reduced adduct levels in sm

281 y of this system across three highly reduced redox states that correlate with unusually high Enemark-

282 Extracellular HMGB1 has different redox states that play distinct roles in inflammation.

283 strate that the catalytic cycle involves two redox states, the three- and five-electron reduced forms

284 A cell-specific regulation of redox state thus balances plasticity and stability of co

285 However, the mechanisms linking redox state to AF are not well understood.

286 ia and changes the mitochondrial NADH/NAD(+) redox state to support ATP production.

287 proline dehydrogenase active site and flavin redox state to the distal membrane association domain.

288 Transition from a broad range of redox states to a uniformly reducing cytosol facilitates

289 The extreme sensitivity of surface redox states to temperatures, to gas pressures and to el

290 d to be controlled exclusively by the enzyme redox state under physiological conditions.

291 hat responds to changes in the intracellular redox state via reversible oxidation of tandem methionin

292 Not only does PFE allow control of redox states via the electrode potential but also the im

293 ity, Akt activity, and cytosolic NADH/NAD(+) redox state were temporally linked in individual cells a

294 the NAD(P)H redox state, pyridine nucleotide redox states were unaffected by pharmacological or genet

295 of the reversible switching between the two redox states, which is associated with large differences

296 * site accesses the 1-hole and fully reduced redox states, while the Cu(Z) site accesses the 2-hole a

297 D(+), an important cofactor linking cellular redox states with energy metabolism.

298 lopment of molecules that can switch between redox states with paired and unpaired electrons is impor

299 Furthermore, they have an imbalanced redox state, with downregulation of the antioxidant enzy

300 ping metal turnover, protein association and redox state within these structures.