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1 ajor phosphatase revealed that the enzyme is redox sensitive.
2 uggesting that FasL activation of Akt/PKB is redox sensitive.
3 ors Ets-1 and c-Jun to the MMP-1 promoter is redox sensitive.
4 Plastidic isoforms were redox sensitive.
5 re prevented, suggesting that the pathway is redox-sensitive.
6 smooth muscle, have certain members that are redox-sensitive.
7 neither the AP1/Ets regulatory sites nor the redox sensitive (-1607/2G) site in MMP-1 promoter are in
8 rombogenicity through angiotensin II-induced redox-sensitive activation of mitogen-activated protein
12 hypoxia may have an independent influence on redox-sensitive adaptive responses to exercise and exerc
13 sformation may be mediated, in part, through redox-sensitive AKT signal transduction pathways by up-r
14 g the crucial role of these highly conserved redox-sensitive amino acid residues for P-protein activi
18 or barrier to a cure for AIDS is exquisitely redox sensitive and could be selectively targeted by Trx
21 on also led to oxidative inactivation of the redox-sensitive and ERK-specific phosphatase, DUSP3/VHR,
22 suggest that ubiquitination of lung ENaC is redox-sensitive and may have significant implications fo
23 Zn/Fe(T) (where Fe(T) = Fe(2+) + Fe(3+)) is redox-sensitive and retains a memory of the valence stat
25 Two novel prodrug polymers POEG-b-PSSDas (redox-sensitive) and POEG-b-PCCDas (redox-insensitive),
26 y reversible by addition of reducing agents (redox sensitive), and independent of both cAMP/protein k
27 t mTORC2 complex stability and activation is redox sensitive, and further defined a novel role for p2
28 oderm: since the activity of bZIP factors is redox sensitive, and the initial polarization of oral vs
29 Zn(2+)-LpxC, the activity of Fe(2+)-LpxC is redox-sensitive, and a time-dependent decrease in activi
31 vide novel insights for targeting endogenous redox-sensitive antioxidant pathways to ameliorate the d
32 , and sequence analyses, we propose that the redox-sensitive APSK evolved after bifurcation of the su
34 anges cellular metabolism and thus activates redox-sensitive as well as oxygen-dependent signal trans
36 or TXNIP increases catalytic activity of the redox-sensitive ATG4B cysteine endopeptidase, leading to
37 erythroid 2 p45-related factor 2 (Nrf2) is a redox-sensitive basic leucine zipper transcription facto
42 related ODA light chains LC3 and LC5 and the redox-sensitive Ca2+ -binding subunit of the docking com
43 cal production as measured by Quest MRI, and redox-sensitive calcium dysregulation as measured by man
46 ere we report that TRPM2, a nonselective and redox-sensitive cation channel, inhibited ROS production
49 These results support the hypothesis that a redox-sensitive checkpoint regulated the progression of
50 tric oxide (NO) synthesis, eNOS requires the redox-sensitive cofactor tetrahydrobiopterin (BH(4)); ho
51 er the speciation, and thus the mobility, of redox-sensitive contaminants including Cr(VI) is of grea
52 he CXXC motif of Spx, which is necessary for redox sensitive control of Spx activity in response to o
53 " moieties, polyethylene glycol (PEG) units, redox-sensitive cross-linker, and tumor-specific targeti
54 f alternate functional motifs such as 'KGD', redox-sensitive Cys and hydrophobic Trp/Phe residues arg
56 TRPA1 activation was dependent on essential redox-sensitive cysteine and lysine residues within N-te
57 hydrophobic clamp, including insertion of a redox-sensitive cysteine pair, confirms the importance o
58 ole in the phosphorelay signaling, where its redox-sensitive cysteine residue may provide additional
59 the C797S variant, confirming Cys-797 as the redox-sensitive cysteine residue that regulates kinase a
60 his approach to the analysis of the free and redox-sensitive cysteine residues of a large membrane pr
62 ochemically, confirming that the C-terminal, redox-sensitive cysteine residues reside within the inte
67 nient method for identifying and quantifying redox-sensitive cysteines in membrane proteins of native
71 other cellular components through energy- or redox-sensitive cytosolic kinase signalling and transcri
73 try and secondary ion mass spectrometry) and redox-sensitive detrital grains--reveal that the origina
74 (D,L-lactide-co-glycolide) polymeric core by redox-sensitive disulfide bond, while TET was physically
76 so reveals the presence of a solvent-exposed redox-sensitive disulphide bridge, unique among the subt
78 scovered that a colorimetric sensor array of redox sensitive dyes can detect even very low levels of
81 gII-activated sources of ROS, the downstream redox-sensitive effectors, Ang-(1-7)-stimulated increase
82 s an integrated redox "hub" linking upstream redox-sensitive effects of BH4 and glutathione with redo
85 channels to H2S required the presence of the redox-sensitive extracellular residue H191, which is als
86 hibitory action requires the presence of the redox-sensitive, extracellular region of the channel whi
88 ve this debate, we use a novel, ratiometric, redox-sensitive fluorescence resonance energy transfer (
89 e oxygen species (ROS) were detected using a redox-sensitive fluorescent dye, a cytochrome c reductio
90 In this issue, Merksamer et al. exploit a redox-sensitive fluorescent protein to monitor the envir
93 ucial role in this process, although several redox-sensitive genes, proteins and transcription factor
95 to evaluate in vivo RBC redox status using a redox sensitive GFP (roGFP2) sensor under control of a b
96 by a redox-based topology assay (ReTA) with redox-sensitive GFP and confirmed by a protease protecti
98 geted viral gene transfer vectors expressing redox-sensitive GFP fused to sensor domains to measure H
102 n this study, we describe a system that uses redox-sensitive GFP to nondisruptively measure real-time
103 uence the redox status of cells, we utilized redox sensitive GFP2 (roGFP2) to determine the redox sta
105 2)) augments cellular ROS as detected by the redox-sensitive green fluorescent protein (roGFP) but do
107 orff-perfused hearts based on the use of the redox-sensitive green fluorescent protein 2, coupled to
108 iol redox status by mitochondrially targeted redox-sensitive green fluorescent protein and measuremen
109 g of the hepatic GSH redox potential using a redox-sensitive green fluorescent protein biosensor show
112 ings were corroborated by measurements using redox-sensitive green fluorescent protein, another prote
113 ) cytosolic oxidation (e.g. oxidation of the redox-sensitive Green fluorescent protein2 probe), (3) a
114 from the development of genetically encoded redox-sensitive green fluorescent proteins (roGFPs), whi
116 suggest that 6-TGNP can also react with the redox-sensitive GXXXCGK(S/T)C and GXXXXGK(S/T)C motif of
117 rn reacts with the Cys(20) side chain of the redox-sensitive GXXXCGK(S/T)C motif of RhoC to produce a
119 Loss of NRF2 decreased the expression of the redox-sensitive histone deacetylase, HDAC4, resulting in
122 nder gene mutations in MDSs license a common redox-sensitive inflammasome circuit, which suggests new
124 A cysteine-null mutant FKBP12.6 retained redox-sensitive interaction with RyR2, suggesting that t
129 situ equilibrium redox titrations and thiol redox-sensitive labeling studies showed that the gamma s
130 llular compartments, influence the status of redox-sensitive macromolecules, and protect against oxid
131 ion of their potential for use in assembling redox-sensitive magnetic resonance imaging contrast agen
134 ubiquitin-mediated degradation by Keap1 in a redox-sensitive manner through modifications of distinct
135 e 15-Lox1-15(S)-HETE axis activates EGFR via redox-sensitive manner, which in turn mediates Src-Jak2-
138 s of F. tularensis prevent the activation of redox-sensitive MAPK signaling components, NF-kappaB sig
142 tivity, thereby raising the possibility that redox-sensitive mechanisms underlie amino acid-dependent
145 ry direct evidence of crystallization from a redox-sensitive metallic liquid phase in the deep mantle
146 ns of Hg and lesser amounts of As, and other redox sensitive metals to groundwater and surface water.
147 record expansion of the oceanic inventory of redox-sensitive metals and the growth of the marine sulp
148 s with low affinity for organic matter, some redox-sensitive metals, and some metals with exceptional
149 agation of the reaction front is retarded by redox-sensitive mineral dissolution reactions and carbon
150 CHCHD4, which is the central component of a redox-sensitive mitochondrial intermembrane space import
151 e to oxidative stress and identified a novel redox-sensitive mitochondrial TXNIP-Trx2-ASK1 signaling
152 oxidative stress, our studies focused on the redox-sensitive mitogen-activated protein kinase kinase
154 es a previously undefined mechanism by which redox-sensitive molecules signal via apoptotic pathways
160 t the TSC complex plays an important role in redox-sensitive mTORC1 regulation and argues for the act
162 alters the abundance and oxidation state of redox-sensitive multiple proteins and that these changes
164 mediated production of ROS and activation of redox-sensitive NF-kappaB were PKCdelta dependent, sugge
165 hly regulated defense systems, including the redox sensitive Nrf2-Keap1 signaling pathway involved in
166 uclear factor-kappaB p65, a component of the redox-sensitive nuclear transcription factor nuclear fac
171 veal a strategy for limiting expression of a redox-sensitive pathway by using a thiol-based redox swi
172 unx2 in diabetes mellitus is regulated via a redox-sensitive pathway that involves a direct interacti
173 and adipose tissue/adipocytes and focused on redox-sensitive pathways, Rho kinase activity, and prote
175 inducing MAPK p38alpha, belong to a group of redox-sensitive phosphatases (protein tyrosine phosphata
178 ed hydrogen peroxide, activation of vascular redox-sensitive PKG-1, and downregulation of Rho kinase
179 g flow cytometry, oxidative stress using the redox-sensitive probe dihydroethidium, tissue factor act
181 s upon IL-4 treatment suggests more than one redox-sensitive protein implicated in this pathway.
182 decreased thrombin-induced activation of the redox-sensitive protein kinases (Janus kinase 2, Akt, an
184 ication of specific cysteine residues within redox-sensitive protein targets, including Cys797 in the
188 mediated post-translational modifications of redox-sensitive proteins are postulated as a key mechani
190 essential E. coli genes encode one-third of redox-sensitive proteins, a finding that might explain t
192 n is largely dependent on the development of redox-sensitive proxies, many of which remain unexplored
193 asuring the oxidation state distribution for redox sensitive radionuclides and other metal ions is ch
196 )Tc-DTPA as noninvasive imaging probes for a redox-sensitive radiotracer and a conservative flow trac
202 ryonic fibroblast cells, suggesting that the redox-sensitive regulation of mTORC1 occurs independent
204 y and conserved cysteine provides an unusual redox-sensitive regulation to an enzyme functioning in b
205 conclusion, we identified MKP-1 as a central redox-sensitive regulator of monocyte adhesion and migra
206 gh-mobility group box 1 protein (HMGB1) is a redox-sensitive regulator of the balance between autopha
207 cystathionine beta-synthase (CBS) acts as a redox-sensitive regulator that impairs CBS activity upon
210 disulfide proteome, a structural group and a redox-sensitive regulatory group, with the latter having
216 issues throughout the body and activate many redox-sensitive signal transduction and gene expression
218 ases in reductants, such as glutathione, and redox sensitive signaling molecules, such as AP endonucl
219 itoNEET suggest that it may participate in a redox-sensitive signaling and/or in Fe-S cluster transfe
220 nfected macrophages to prevent activation of redox-sensitive signaling components that ultimately res
221 on affects skeletal muscle's performance and redox-sensitive signaling during the inflammatory and re
222 d H2O2 production resulted in disturbance of redox-sensitive signaling including Akt and MAPKs pathwa
223 induced increase in ROS production triggered redox-sensitive signaling mechanism emanating from the c
224 spectrometry-based approach to elucidate the redox-sensitive signaling network (redoxome) mediating t
226 cxcl8 gene expression, via the activation of redox-sensitive signaling pathways, and further point ou
231 This review will highlight two important redox sensitive signalling pathways that contribute to R
232 hem (reactive oxygen species, ROS) stimulate redox-sensitive signalling pathways to modify the cellul
233 duced (i) ROS generation, (ii) activation of redox-sensitive signalling pathways, and (iii) ROS stres
234 sensitivity was mediated by an extracellular redox-sensitive site, which was also highly sensitive to
235 e heads, temperatures, and concentrations of redox-sensitive species, iomeprol and 15 of its transfor
236 n that wound-induced H2O2 is detected by the redox-sensitive Src family kinase (SFK) Lyn within the r
241 induced by reactive oxygen species (ROS) on redox-sensitive targets such as zinc finger proteins pla
243 116 ppb) O(3) concentrations was examined by redox-sensitive thiol labeling, mass spectrometry, and t
244 oxidant stress, confirming that Cys405 is a redox-sensitive thiol that is necessary for ET(B)-eNOS s
246 also show that the FAD 2'-OH group acts as a redox-sensitive toggle switch that controls PutA-membran
247 e zinc center of Hsp33 appears to act as the redox-sensitive toggle that adjusts the thermostability
250 ion is consistent with crustal abundances of redox-sensitive trace elements in saponitic mudstones de
251 xidizing equivalents to mobilize sulfate and redox-sensitive trace metals from land to the oceans whi
252 rant benthic foraminiferal species, peaks in redox-sensitive trace metals, and enhanced (15)N/(14)N r
256 ed adenosine triphosphate content, and Nrf2 (redox sensitive transcription factor) up-regulation.
258 by regulating the signals that activate the redox-sensitive transcription factor NF-kappaB and cause
259 essential micronutrient that suppresses the redox-sensitive transcription factor NF-kappaB-dependent
260 Minocycline reduces ubiquitination of the redox-sensitive transcription factor Nrf2 and increases
261 demonstrate that Cu((II))ATSM activates the redox-sensitive transcription factor Nrf2 in human coron
262 unction of minocycline, which stabilizes the redox-sensitive transcription factor Nrf2, thus protecti
263 ion of MIOX induced nuclear translocation of redox-sensitive transcription factor Nrf2, which binds t
267 rythroid 2-related factor 2 (Nrf2/NFE2L2), a redox-sensitive transcription factor plays a critical ro
268 ear erythroid 2-related factor 2 (Nrf2) is a redox-sensitive transcription factor that is the key reg
269 erythroid 2 p45-related factor 2 (Nrf2) is a redox-sensitive transcription factor that regulates expr
270 tor erythroid-2-related factor 2 (Nrf2) is a redox-sensitive transcription factor that regulates the
271 erythroid 2 p45 related factor-2 (Nrf2) is a redox-sensitive transcription factor that up-regulates a
273 ammatory processes as follows: activation of redox-sensitive transcription factors (NFkappaB) and MAP
274 mistry to determine DNA-bound potentials for redox-sensitive transcription factors because such bindi
275 the genome and facilitates the activation of redox-sensitive transcription factors globally in respon
276 ytoprotective proteins through activation of redox-sensitive transcription factors is severely attenu
277 active oxygen species-mediated activation of redox-sensitive transcription factors is the hallmark of
278 at DNA-binding sites (response elements) for redox-sensitive transcription factors may also exist in
279 also prevented the LPS-induced activation of redox-sensitive transcription factors such as NF-kappaB
280 sponses to contraction include activation of redox-sensitive transcription factors such as nuclear fa
281 xygen species which induce the activation of redox-sensitive transcription factors that interact with
282 against oxidative stress are coordinated by redox-sensitive transcription factors that transduce oxi
283 ecipitation assays showed that the prototype redox-sensitive transcription factors, Nrf2, small Maf p
285 tion governing TrfA activity, wherein Spx, a redox-sensitive transcriptional regulator degraded by Cl
286 based on the authigenic accumulation of the redox-sensitive transition element molybdenum in sulphid
287 e of molecular oxygen (P = 3.4 x 10(-8)) and redox-sensitive transition metals and compounds, which i
288 aphy reveals an episode of enrichment of the redox-sensitive transition metals molybdenum and rhenium
289 phosphate oxidase and the activation of the redox-sensitive tyrosine kinase Pyk2 as essential for VE
290 Proline-rich tyrosine kinase 2 (PYK2), a redox-sensitive tyrosine kinase, directly phosphorylates
291 induces oxidation of target cysteines in the redox-sensitive tyrosine phosphatases, LMW-PTP and SHP-2
292 iple levels by Keap1, which targets Nrf2 for redox-sensitive ubiquitin-mediated degradation in the cy
296 ls of endocytic compartments by expressing a redox-sensitive variant of GFP fused to various endocyti
297 show, using transgenic mice that expressed a redox-sensitive variant of green fluorescent protein tar
298 rylation at Ser1177 as well as expression of redox-sensitive vascular cell adhesion molecule-1 (VCAM-
300 ealed that microvascular K(ATP) channels are redox sensitive, with oxidants increasing their activity
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