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1 nment to 1 year of trastuzumab significantly reduced the risk of a disease-free survival event (HR 0.
2 Q-HDM and 12 SQ-HDM doses both significantly reduced the risk of a moderate or severe asthma exacerba
3 tion of donated blood products substantially reduces the risk of a number of transfusion-related comp
6 tics, the use of cytolytic induction therapy reduced the risk of acute rejection by 32% (OR 0.68, 0.6
7 n-2-receptor antibody (IL-2RAb) induction in reducing the risk of acute rejection in adult kidney tra
8 on of a high number of different solid foods reduced the risk of AD (P trend = 0.02 at 4 months of ag
11 nce and concentration in source manure would reduce the risk of AGI from exposure to manure irrigatio
12 atin treatment compared with placebo did not reduce the risk of AKI overall, among patients naive to
14 emic stroke as their index event, betrixaban reduced the risk of all-cause stroke (0.72% versus 1.48%
15 cillus Calmette-Guerin (BCG) vaccination may reduce the risk of allergic diseases, including atopic d
16 controlled trials) showed that cell therapy reduced the risk of amputation by 37%, improved amputati
18 lergens, to increase tolerance threshold, to reduce the risk of anaphylaxis, and to improve the patie
19 administration of insulin before surgery to reduce the risk of anesthesia-induced cognitive decline
20 ting increases targetable tumor antigens and reduces the risk of antigen-negative disease escape.
21 reatment constitutes a potential strategy to reduce the risk of antimicrobial resistance among childr
23 y suitable for targeting neuroanatomy, as it reduces the risk of artifacts and is faster than classic
24 polyunsaturated fatty acids in pregnancy can reduce the risk of asthma in offspring and allergic resp
26 care, weight loss through bariatric surgery reduced the risk of atrial fibrillation among persons be
29 nates bias.Although all these approaches can reduce the risk of bias in observational studies, none r
31 nated central venous catheters significantly reduced the risk of bloodstream infections compared with
32 ve been demonstrated in randomized trials to reduce the risk of both invasive and DCIS recurrence, bu
33 he mechanisms by which exercise training can reduce the risk of brain diseases, inform the optimizati
34 rs of cancer by health-care practitioners to reduce the risk of breast cancer-related lymphoedema are
36 vestigated the effectiveness of tamoxifen in reducing the risk of breast cancer among women at increa
38 of evidence suggests that CMVIG prophylaxis reduces the risk of bronchiolitis obliterans syndrome, b
39 long-chain polyunsaturated fatty acid, might reduce the risk of bronchopulmonary dysplasia, but appro
42 types of cancer; * Support policy efforts to reduce the risk of cancer through evidence-based strateg
45 ous physical exercise is an effective way to reduce the risk of cardiovascular (CV) disease, CAHAP re
49 nt kidney disease at baseline, empagliflozin reduced the risk of cardiovascular death by 29% compared
51 ent with ticagrelor + low-dose aspirin (ASA) reduces the risk of cardiovascular (CV) death, MI, or st
53 that the use of statins to lower cholesterol reduces the risk of cardiovascular events among persons
54 otics closer to the first dose of antibiotic reduces the risk of CDI by >50% in hospitalized adults.
55 uantities of gluten at 4-6 mo of age did not reduce the risk of celiac disease (CD) in a group of hig
56 weaning to an extensively hydrolyzed formula reduced the risk of celiac disease autoimmunity or celia
59 ional and sensorial quality and potential to reduce the risk of chronic diseases such as obesity and
60 hytochemicals confers benefits for health by reducing the risk of chronic diseases via regulation of
61 ffectively help slow disease progression and reduce the risk of cirrhosis, hepatocellular carcinoma (
62 with immune active chronic HBV infection in reducing the risk of cirrhosis, decompensated liver dise
65 ation therapy with ambrisentan and tadalafil reduces the risk of clinical failure events compared wit
67 cate prophylactic CNS-directed therapies may reduce the risk of CNS involvement; however, no consensu
68 atment with oral corticosteroids may help to reduce the risk of CNVM development, and anti-VEGF thera
72 nknown whether naturally acquired antibodies reduce the risk of colonization with strains expressing
73 ent regimens for children with ependymoma to reduce the risk of complications associated with therapy
75 iagnosis, while preventive chemotherapy will reduce the risk of contacts developing the disease by 50
76 rbonate rather than isotonic sodium chloride reduces the risk of contrast-associated acute kidney inj
78 olled trial to determine whether minocycline reduces the risk of conversion from a first demyelinatin
80 viduals with LDL-C >/=190 mg/dL, pravastatin reduced the risk of coronary heart disease by 27% (P=0.0
81 iduals without vascular disease, pravastatin reduced the risk of coronary heart disease by 27% (P=0.0
82 entions could be preferentially effective in reducing the risk of coronary heart disease in individua
84 t reduce P loads alone may not significantly reduce the risk of cyanobacterial blooms in western Lake
85 for stable coronary artery disease does not reduce the risk of death and myocardial infarction compa
87 ermia initiated at 6 to 24 hours after birth reduces the risk of death or disability at 18 months amo
89 the cyclooxygenase enzymes COX-1 and COX-2, reduce the risk of developing Alzheimer's disease in nor
90 ave suggested that a flavonoid-rich diet can reduce the risk of developing cardiovascular disease.
94 R) inhibitors called statins at mid-life can reduce the risk of developing sporadic Alzheimer's disea
96 of asthma rescue medications at cohort entry reduced the risk of developing obesity (hazard ratio, 0.
98 ype HLA-C2, expressed by fetal trophoblasts, reduces the risk of developing pregnancy complications.
101 ied the efficacy of each control strategy in reducing the risks of different transmission routes.
103 n as possible in all HIV infected persons to reduce the risk of disease progression and prevent trans
104 ted neoadjuvant and adjuvant immunotherapies reduce the risk of disease relapse after resection of mu
106 dherence to reprocessing protocols, may help reduce the risk of duodenoscope-associated infection tra
107 confirm that medical treatment substantially reduces the risk of early recurrent stroke after TIA and
109 ptibility gene variant at rs6736278 (CAPN14) reduced the risk of EoE (adjusted odds ratio, 0.08; 95%
110 cts that are vital for these functions, thus reducing the risk of epilepsy surgery causing new morbid
111 e of depression and insomnia, a novel way to reduce the risk of escalating depression might be to off
113 the SQ grass sublingual immunotherapy tablet reduced the risk of experiencing asthma symptoms and usi
114 ublingual immunotherapy tablet significantly reduced the risk of experiencing asthma symptoms or usin
115 while shock testing seems safe, it does not reduce the risk of failed shocks or prolong survival.
116 o increase the probabilities of survival and reduce the risk of failing to meet the minimum needs for
117 r (ChI) might improve cognitive function and reduce the risk of falls in patients with PD, although i
118 an greatly increase the confidence in calls, reduce the risk of false positives, and help characteriz
119 smoking, quitting areca nut chewing may also reduce the risk of first recurrence in NMBIC patients, m
121 Assessing liver health may be important for reducing the risk of future CHF events, particularly amo
122 bacter pylori infection has been reported to reduce the risk of gastric cancer among asymptomatic ind
123 sis regimen available to most patients while reducing the risk of generating additional drug resistan
124 othesized that higher vitamin A levels would reduce the risk of graft-versus-host disease (GVHD) thro
125 fective strategies that may be considered to reduce the risk of having a child with developmental def
126 Additionally, metformin was effective in reducing the risk of HCC when compared with sulphonylure
127 Alumni", established that more strenuous PA reduced the risk of heart attack and that it was necessa
128 roved by physical activity, which might also reduce the risk of hepatic encephalopathy through an inc
130 g the offspring of one breeding season while reducing the risk of hidden inbreeding due to related fo
131 Bisphosphonates (generic) and denosumab reduce the risk of hip, nonvertebral, and vertebral frac
132 daily as pre-exposure prophylaxis (PrEP) can reduce the risk of HIV infection by 49% in people who in
133 A monthly vaginal ring containing dapivirine reduced the risk of HIV-1 infection among African women,
135 ove the efficacy of public health efforts to reduce the risk of hormone-sensitive cancers and other n
138 on and interventions undertaken, to date, to reduce the risk of human infection through these routes.
139 aches has dramatically improved survival and reduced the risk of human herpesvirus 8 (HHV8)-associate
140 mption of egg protein from age 4 to 6 months reduces the risk of IgE-mediated egg allergy in infants
141 ing Mendelian randomization suggest that ALT reduces the risk of IHD, probably through reducing trigl
143 achycardia therapy programming significantly reduced the risk of inappropriate ICD therapy compared w
144 Innovative ICD programming significantly reduces the risk of inappropriate ICD therapy in both IC
145 suggest that long-duration breastfeeding may reduce the risk of incident hypertension in middle age.
149 these biomarkers may enable interventions to reduce the risk of inflammatory complications following
151 sults suggest that novel oral anticoagulants reduce the risk of intraocular bleeding by approximately
152 practices, wherein raising hemoglobin could reduce the risk of ischemia in a critically hypoperfused
158 reed that available evidence shows that PMRT reduces the risks of locoregional failure (LRF), any rec
160 H) in patients with hypertension and whether reducing the risk of LVH explains the reported cardiovas
162 impaired glucose tolerance, acarbose did not reduce the risk of major adverse cardiovascular events,
163 of losmapimod compared with placebo did not reduce the risk of major ischemic cardiovascular events.
164 iacin with laropiprant did not significantly reduce the risk of major vascular events and increased t
165 a sodium-glucose cotransporter 2 inhibitor, reduced the risk of major adverse cardiovascular events
168 ion in systolic blood pressure significantly reduced the risk of major cardiovascular disease events
169 randomised trials shows that statin therapy reduces the risk of major vascular events (ie, coronary
173 physical function, and quality of life, and reduce the risk of malnutrition in sarcopenic elderly pe
174 the treatment of various diseases, including reducing the risk of many chronic degenerative disorders
176 mpts should continue to explore therapies to reduce the risk of mortality or hospitalization for thes
178 c dysfunction, biventricular pacing not only reduces the risk of mortality/morbidity, but also leads
180 We conclude that PNT has the potential to reduce the risk of mtDNA disease, but it may not guarant
181 nd nonfatal heart failure events but did not reduce the risk of myocardial infarction or stroke in di
182 nd avoidance of bovine-origin products might reduce the risk of necrotising enterocolitis, but the ab
183 nd avoidance of bovine-origin products might reduce the risk of necrotising enterocolitis, but the ab
188 may make it possible to prevent or at least reduce the risk of norovirus outbreaks by closing potent
190 is valid, bone preservative strategies could reduce the risk of osteoporosis/fractures among ICU surv
195 2.48]), and tetracycline therapy appeared to reduce the risk of Parkinson disease (adjusted IRR, 0.98
196 cated nurses working in acute care areas can reduce the risk of patient mortality, although the evide
199 h malignant obstruction, rectal indomethacin reduced the risk of PEP by 64% (OR, 0.36; 95% CI, 0.17-0
200 ion of and treatment for PTSD symptoms might reduce the risk of perinatal depression in post-conflict
201 (RR=1.98, 95% CI 1.64 to 2.38; p<0.001), and reduced the risks of periprocedural symptomatic intracra
204 , adding monthly DP to daily TMP-SMX did not reduce the risk of placental or maternal malaria or impr
205 g cleaner burning biomass-fuelled cookstoves reduced the risk of pneumonia in young children in rural
206 g cleaner burning biomass-fuelled cookstoves reduced the risk of pneumonia in young children in rural
207 eurectomy at the time of hernia repair would reduce the risk of postoperative pain for open tension-f
208 pressure, compared with standard management, reduced the risk of postoperative organ dysfunction.
211 l benefits of nepafenac 0.3% over vehicle in reducing the risk of postoperative ME, with the integrat
213 ld be one of the most scalable strategies to reduce the risk of premature mortality from atherosclero
214 Nations set key targets to reach by 2025 to reduce the risk of premature noncommunicable disease dea
215 er vaginal progesterone prophylaxis given to reduce the risk of preterm birth affects neonatal and ch
216 rogesterone administration has been shown to reduce the risk of preterm birth and neonatal morbidity
219 subjects with early/mild COPD to potentially reduce the risk of progressing to more advanced lung dis
222 eutic and diagnostic radiation treatments to reduce the risk of radiation-related adverse systemic ef
223 irmed this effect modification: atorvastatin reduced the risk of reaching the primary endpoint in the
224 duction in PP, which may have contributed to reduce the risk of rebleeding and of further decompensat
225 OP, an air tamponade duration beyond 2 hours reduced the risk of rebubbling (HR 0.36 [95% CI 0.18-0.7
226 s leucovorin (FU + LV) adjuvant chemotherapy reduced the risk of recurrence and death across all time
227 e, the use of anakinra compared with placebo reduced the risk of recurrence over a median of 14 month
229 emotherapy with fluoropyrimidine monotherapy reduces the risk of recurrence and death by approximatel
230 for estrogen receptor-positive breast cancer reduces the risk of recurrence by approximately one-half
231 Whether closure of a patent foramen ovale reduces the risk of recurrence of ischemic stroke in pat
233 3 to 5 years was not found to significantly reduce the risk of recurrent colorectal adenomas in a re
234 otide, a somatostatin analog, is proposed to reduce the risk of recurrent GI bleeding in this populat
235 , adding ticagrelor to aspirin significantly reduces the risk of recurrent ischemic events, including
236 ential reintroduction sites is important for reducing the risk of reintroduction failure of endangere
238 hereditary liver diseases, which may likely reduce the risk of rejection and the need for lifelong i
239 induction therapy, as compared with IL-2RA, reduces the risk of rejection, graft loss, and death in
240 ogous stem-cell transplantation (autoSCT) to reduce the risk of relapse, although the benefit of this
241 analysis of the efficacy of this approach in reducing the risk of relapse in major depressive disorde
242 ontrolled manner and has to be considered to reduce the risk of retinal break formation and to preven
243 e can prevent ZIKV disease and be adapted to reduce the risk of sensitizing individuals to subsequent
247 ic BP lowering to a target of <130 mm Hg may reduce the risk of several important outcomes including
248 onsteroidal anti-inflammatory drugs (NSAIDs) reduces the risk of several cancers, but it is not clear
252 he elimination of cardiopulmonary bypass may reduce the risk of short-term mortality, renal failure,
256 ng antibiotics from animal diets and thereby reducing the risk of spreading antibiotic resistance ass
257 whether the use of aspirin and other NSAIDS reduces the risk of squamous cell carcinoma (SCC), we co
260 administration of SAP did not significantly reduce the risk of SSI compared with late administration
262 s with the factor Xa inhibitor betrixaban to reduce the risk of stroke compared with standard-dose en
265 ing patients with acute stroke for dysphagia reduces the risk of stroke-associated pneumonia (SAP), o
270 enom immunotherapy (VIT) could substantially reduce the risk of subsequent severe systemic sting reac
271 ntervention; however, stenting significantly reduces the risk of subsequent pulmonary vein restenosis
272 equate adherence to recommendations known to reduce the risk of sudden unexpected infant death has co
274 enous cefazolin compared with saline did not reduce the risk of surgical site infection within 30 day
275 interface to achieve systemic levels, while reducing the risk of systemic toxicity seen with parenta
276 for strengthening primary care provision and reducing the risks of systems failures were then identif
277 d to consider dietary supplements that might reduce the risk of the disease progressing from the inte
279 placebo, evolocumab treatment significantly reduced the risk of the primary end point (1344 patients
280 e risk of cardiovascular events primarily by reducing the risk of the development or progression of h
283 py (DAPT) with a P2Y12 inhibitor and aspirin reduces the risk of thrombosis and stroke but increases
284 of NIV compared with standard oxygen therapy reduced the risk of tracheal reintubation within 7 days.
286 with an restrictive transfusion protocol did reduce the risk of transfusion in moderately anemic pati
287 s crucial to improve health interventions to reduce the risk of transmission between pigs and from pi
288 suggesting that slaughter interventions may reduce the risk of transmission of ARDs to beef consumer
290 ol can complement preventive chemotherapy by reducing the risk of transmission from snails to humans.
291 innate and adaptive immunity can effectively reduce the risk of tumor recurrence after surgery, facil
299 rapaxar and ticagrelor pooled) significantly reduced the risk of VTE by 29% compared with background
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