ライフサイエンスコーパス: reduced form of

1 lse was nearly identical to the one-electron-reduced form of 1,4,5,8-naphthalene diimide (produced in

2 ivalents), but reacts rapidly with the fully reduced form of 1-methoxy-5-methylphenazinium methylsulf

3 oxygen, suggesting activation of O(2) by the reduced form of 1.

4 The reduced form of 17-AAG is differentiated from its oxidiz

5 Instead, the reduced form of 31 behaves as an electrogenerated base,

6 ies with pH and exhibits a pKa value for the reduced form of 7.5.

7 rdF does not react with O2, but it binds the reduced form of a conserved flavodoxin-like protein, Nrd

8 By integrating a reduced form of a fully coupled atmospheric model within

9 st example of crystallization of a substrate-reduced form of a Se- and Mo-containing enzyme.

10 nt differential binding between oxidized and reduced forms of a 5-deazariboflavin derivative that is

11 f the binding constants for the oxidized and reduced forms of a bound species, binding free energy (d

12 Switching in situ between the oxidized and reduced forms of a metal complex resulted in a change in

13 This reduced form of alpha-ketoisocaproic acid was found to s

14 Dihydrolipoic acid (the reduced form of alpha-lipoic acid), which contains free

15 the interconversion between the oxidized and reduced forms of androgens and estrogens at the 17 posit

16 The emergence of a reduced form of astatine, At(2), at higher radiation dos

17 At(2) was identified as a reduced form of astatine, presumably astatide, which cou

18 We demonstrate that the reduced form of Bacillus subtilis OhrR binds cooperative

19 Partially and fully reduced forms of benzo-fused eight- to ten-membered nitr

20 A new method for the synthesis of the reduced form of beta-nicotinamide [U-14C]adenine dinucle

21 ces to a greater iron-copper distance in the reduced form of bo(3) compared to that of ba(3).

22 Reduced forms of both AphB and OhrR directly bind to the

23 The reduced forms of both pyridine nucleotides are fluoresce

24 The disulfide-reduced form of bovine ribonuclease A, with the Cys thio

25 5 inhibits fatty acid synthesis; (b) C273, a reduced form of C75, is unable to inhibit fatty acid syn

26 ditions of the aromatic ketone reduction, or reduced form of Celastrol, had significantly decreased t

27 was also carried out, demonstrating that the reduced forms of CPR and CYP2C9 interact differently wit

28 Here we present the NMR structure of the reduced form of Cr-TRP16, along with its regulation of N

29 e mixed-valence form and 2.52 A in the fully reduced form of CuA.

30 Surprisingly, the reduced forms of cyclic nitroxides, cyclic hydroxylamine

31 be required to promote the formation of the reduced form of Cys 266, which is otherwise unreactive.

32 t with a square scheme in which oxidized and reduced forms of cyt P450s each participate in rapid con

33 The reduced form of cytochrome c2 strongly binds to reduced

34 tron reduction at -0.09 V vs SCE (MeCN), and reduced forms of DCNT have yet to be isolated and charac

35 We conclude that both oxidized and reduced forms of dCRY are capable of photosignaling.

36 y than its reduced form and the oxidized and reduced forms of Defr1 Y5C.

37 he reduced form of the wild-type enzyme, the reduced form of DeltaP34 Trx has disulfide isomerization

38 In contrast, the reduced forms of disulfiram and cystamine, diethyl dithi

39 In addition, two reduced forms of DMSO reductase, prepared either anaerob

40 n and reduction are effected by oxidized and reduced forms of E. coli thioredoxin.

41 tial, consistent with oxygen reacting with a reduced form of enzyme before release of the carbonyl pr

42 te indicated that the catalytically relevant reduced form of enzyme is an anionic flavin semiquinone,

43 studies are now extended to the oxidized and reduced forms of ferredoxin I from spinach.

44 ng solutions (pH 5.0, 6.0, 7.0) containing a reduced form of flavin mononucleotide (FMNH2, 100 muM),

45 e ligand, only the oxidized and two-electron-reduced forms of FMN are detected.

46 that this is enabled due to the oxidized and reduced forms of FMN-Na being stabilized by resonance st

47 ized, one-electron-reduced, and two-electron-reduced forms of FTR.

48 othesis regarding the unknown peak to be the reduced form of furaneol(R).

49 m effects, including decreased levels of the reduced form of glutathione (GSH) and elevated oxidative

50 and antioxidants N-acetylcysteine (NAC) and reduced form of glutathione (GSH).

51 ect was mimicked by external addition of the reduced form of glutathione ethyl ester.

52 es in plasma, together with decreases in the reduced form of glutathione in erythrocytes.

53 f these protein groups was achieved with the reduced form of glutathione or glutaredoxin, a protein k

54 Glutathione reductase, which regenerates the reduced form of glutathione, represents one such anti-ox

55 ly reversed by dithiothreitol but not by the reduced form of glutathione, suggesting that the disulfi

56 X, the antioxidant N-acetylcysteine, and the reduced form of glutathione.

57 The reduced form of graphene oxide (GO) is an attractive alt

58 ove the oxygen functional groups so that the reduced form of graphene oxide (GO; reduced form: rGO) r

59 The active, reduced form of GSH is rapidly degraded thus making it d

60 tructure, the NMR solution structure for the reduced form of hDim1(1)(-)(128) presented here, along w

61 hat the R391A mutation might destabilize the reduced form of heme b(558).

62 Overall, our results show that the reduced form of HMGB1 coordinates tissue regeneration an

63 f the carmustine type inhibit only the NADPH reduced form of human thioredoxin reductase.

64 131)-Arg(153) peptides from the oxidized and reduced forms of human RNase H1 in the presence and abse

65 BSO (10 micromol/L) depleted the reduced form of intracellular glutathione without induci

66 Fully and partially reduced forms of isolated bovine cytochrome c oxidase un

67 or of vitamin K is strictly dependent on the reduced form of its naphthoquinone ring.

68 The reduced form of JAK2 is the most active form, and the ox

69 he structural similarity between SAc and the reduced form of lipoic acid, a step which is similar to

70 tructures were obtained for the oxidized and reduced forms of M98A and M98Q amicyanins at atomic reso

71 ociation rate constant for NO binding to the reduced form of MPO, MPO-Fe(II), was over an order of ma

72 The biosensor detects reduced forms of MSMA and roxarsone and offers a practic

73 The interaction between Pck and the reduced form of mycobacterial thioredoxin, gene expressi

74 t of a paramagnetic Fe-S compound that binds reduced forms of N2 involved Fe complexes stabilized by

75 Both the oxidized and reduced forms of Na(+)-NQR exhibit a radical EPR signal.

76 RoDH-E2, with cytoplasmic phosphorylated and reduced forms of NAD-dependent retinol dehydrogenase act

77 NADPH/NADP(+) (the reduced form of NADP(+)/nicotinamide adenine dinucleotid

78 ion for relief from inhibition by NADPH (the reduced form of NADP) expected of an adaptive landscape

79 6-diphosphate (FDP), 1.5-fold by oxidized or reduced forms of NADP, and 10-fold by HPr-P (Ser-46).

80 n of FDH and its complexes with oxidized and reduced forms of NADP.

81 drogenase (G6PD) regulates production of the reduced form of NADPH through the pentose phosphate path

82 ed the X-ray structures of oxidized and NADH-reduced forms of naturally folded recombinant murine AIF

83 hysiological temperature of 37 degrees C the reduced form of nicked BoNT/E adopts a dynamically flexi

84 icotinamide adenine dinucleotide(+) (NAD(+))/reduced form of nicotinamide adenine dinucleotid (NADH)

85 ponse to nicotinamide coenzymes, such as the reduced form of nicotinamide adenine dinucleotide (NADH)

86 lar oxidoreductase that is stimulated by the reduced form of nicotinamide adenine dinucleotide (NADH)

87 al and malondialdehyde as substrates and the reduced form of nicotinamide adenine dinucleotide phosph

88 imiting rearrangements of the FAD and NADPH (reduced form of nicotinamide adenine dinucleotide phosph

89 y underlie conidial susceptibility to NADPH (reduced form of nicotinamide adenine dinucleotide phosph

90 n the presence and absence of cofactors (the reduced form of nicotinamide adenine dinucleotide phosph

91 cing systems in vascular wall include NADPH (reduced form of nicotinamide adenine dinucleotide phosph

92 logically important metabolites, such as the reduced form of nicotinamide adenine dinucleotide.

93 ment can simultaneously measure oxidized and reduced forms of nicotinamide adenine dinucleotide (NAD(

94 dinucleotide (NAD(+) and NADH), oxidized and reduced forms of nicotinamide adenine dinucleotide phosp

95 e in this reaction, with NADH and NADPH (the reduced forms of nicotinamide adenine nucleotide and nic

96 ormation on both types of Cu centres for the reduced form of NiR from Alcaligenes xylosoxidans (AxNiR

97 Nitroxyl anion (HNONO(-)), the one-electron reduced form of nitric oxide (NO), induces positive card

98 etection of nitroxyl (HNO), the one-electron reduced form of nitric oxide (NO), is reported.

99 Nitroxyl (HNO), the one-electron-reduced form of nitric oxide, enhances cardiac function

100 Nitroxyl (HNO/NO(-)), the reduced form of nitric oxide, has gained attention based

101 f nitroxyl (HNO), the transient one-electron reduced form of nitric oxide, is a significant challenge

102 ides evidence for nitroxyl, the one-electron reduced form of nitric oxide.

103 ide, evidence for nitroxyl, the one-electron-reduced form of nitric oxide.

104 onary biology of (a) elemental nitrogen; (b) reduced forms of nitrogen such as amines, ammonia, and h

105 e present here the crystal structures of the reduced form of NTR and its complexes with the inhibitor

106 We previously reported that the reduced form of OxyR is sufficient for repression of tra

107 epressed by OxyR(C199S), which resembles the reduced form of OxyR.

108 upporting the proposal that the oxidized and reduced forms of OxyR interact differently with their ta

109 nantly to the increased concentration of the reduced form of P680 ([P+] is low).

110 tide is initially unfolded by binding to the reduced form of PDI.

111 To understand how the reduced form of Pdx is stabilized and how reduction of t

112 -2,2'-bitriazine, [TCBT]*-, the one-electron reduced form of planar (D(2h)) TCBT, which is also struc

113 The reduced form of Prussian blue, called Prussian white, is

114 e presence of the sulfinic form (but not the reduced form) of PrxI induces the conserved cysteine of

115 at recognize epitopes common to oxidized and reduced forms of PTP1B.

116 ized forms of Pu sorb less to sediments than reduced forms of Pu.

117 nd structural properties of the oxidized and reduced forms of Pyrococcus furiosus superoxide reductas

118 Copper also binds the four-electron-reduced form of QSOX with a visible spectrum suggestive

119 The reduced forms of quinone, tert-butylhydroquinone, and 5-

120 y-state voltammograms with both oxidized and reduced forms of redox species initially present in solu

121 Although responses to the reduced forms of redox-active metals, such as Mn(II) and

122 Thus, the unfolded reduced forms of RNase A are not statistical coils with

123 d increase in the propensity of the unfolded reduced forms of RNase A to form the native set of disul

124 angle x-ray scattering showed that the fully reduced form of Rv2466c adopts a "closed" compact confor

125 Strikingly, a new crystal structure of the reduced form of Rv2466c revealed the binding of a C-term

126 The observation of the reduced forms of several metal-containing proteins using

127 The structures of the oxidized and reduced forms of SOR suggest a mechanism by which supero

128 xylated by a P450 monooxygenase to yield the reduced form of sorgoleone.

129 ster ligands C45 and C64 in the oxidized and reduced forms of T4MOC.

130 ere, we report the solution structure of the reduced form of the 98-amino acid Fd domain determined b

131 clearly distinguished the oxidized from the reduced form of the binuclear cluster.

132 atom of PQQ in that study represents the C-5-reduced form of the cofactor and lends support for a hyd

133 n in yeast and that inadequate levels of the reduced form of the cofactor can produce lethality.

134 modified ligand diminish the ability of the reduced form of the complex to serve as a nucleophile bu

135 ical to the Cu...Cu distance observed in the reduced form of the Cu(A) site of thiolate-bridged cytoc

136 we determined the solution structure of the reduced form of the dominant negative human hDim1 (hDim1

137 In the reduced form of the double mutant, an N/O ligand was app

138 undertake a thorough characterization of the reduced form of the enzyme and the determination of the

139 epresents the formation of the four-electron reduced form of the enzyme, EH(4).

140 and the bend increases (25 degrees ) in the reduced form of the enzyme, roughly the conformation pre

141 exhibited cleavage rates comparable with the reduced form of the enzyme, suggesting that the cysteine

142 e heteroduplex substrate comparable with the reduced form of the enzyme.

143 lex requires reaction of O(2)(*)(-) with the reduced form of the enzyme.

144 rential binding of NADP+ to the oxidized and reduced form of the enzyme.

145 neutral FAD radical are also observed in the reduced form of the enzyme.

146 -SSG with GRX led to the regeneration of the reduced form of the enzyme.

147 s a characteristic 1405 cm(-)(1) band of the reduced form of the FMN cofactor.

148 , known clinically as leucovorin, which is a reduced form of the folic acid present in DMEM.

149 The solution structure of the reduced form of the MAL TIR domain, determined by NMR sp

150 K, which was also seen in simulations of the reduced form of the mesophilic Clostridium pasteurianum

151 m bis(hydromethanesulfonate; LMTM), a stable reduced form of the methylthioninium moiety, acts as a s

152 CO binds to the reduced form of the mutants, indicating that it is able

153 equilibrium between two conformations of the reduced form of the oxidase.

154 tion of beta-RFA-P and the accumulation of a reduced form of the proposed cyclohexadienimine reaction

155 t FMOs exist in the cell as a complex with a reduced form of the prosthetic group and NADPH cofactor,

156 The reduced form of the protein exhibited an EPR spectrum ch

157 6, was identified that existed in an already reduced form of the quinone.

158 y and folding of the protein, we studied the reduced form of the recombinant human PrP as well as the

159 ligand was apparent that was not seen in the reduced form of the T1D protein.

160 es that are involved in the transport of the reduced form of the tetrazolium dye 3-(4,5-dimethylthiaz

161 The reduced form of the thromboxane A(2) receptor experience

162 e oxidized enzyme reacts with ubiquinol (the reduced form of the usual electron acceptor) in a proces

163 In contrast to the reduced form of the wild-type enzyme, the reduced form o

164 al spectroscopy (NRVS) to study oxidized and reduced forms of the [4Fe-4S] cluster in the D14C varian

165 isms involving either one- or three-electron reduced forms of the A cluster as immediate precursors t

166 .86 and gav = 1.87 signals characteristic of reduced forms of the active site (center C) of wild-type

167 Reduced forms of the C56S and C60S variants of the thior

168 the variants are similar, EPR spectra of the reduced forms of the cluster show small differences in s

169 owing incubation of NBD-Cl with oxidized and reduced forms of the denatured peroxidase, indicating a

170 Titrations of the reduced forms of the domains with artificial electron ac

171 s performed on the succinate- and dithionite-reduced forms of the enzyme demonstrated that the 4Fe-4S

172 chroism spectral studies of the oxidized and reduced forms of the enzyme suggest the Fe centers to be

173 9-nortestosterone binds to both oxidized and reduced forms of the enzyme with dissociation constants

174 ide and azide were added to the oxidized and reduced forms of the enzyme, and Mn(II) CW-EPR and ESEEM

175 of CuB, in both the fully oxidized and fully reduced forms of the enzyme, has been examined by Cu XAS

176 es suggest that it is the immature disulfide-reduced forms of the familial ALS mutant SOD1 proteins t

177 arison of the structures of the oxidized and reduced forms of the native enzyme shows that the princi

178 The oxygenated and reduced forms of the prosthetic group help stabilize int

179 The crystal structures of the oxidized and reduced forms of the protein reveal that the copper site

180 nces in UDP binding between the oxidized and reduced forms of the protein which most likely explain t

181 te binds to the inactive oxidized and active reduced forms of the protein with similar affinities.

182 In the semiquinone and reduced forms of the protein, the Gly57-Asp58 peptide ad

183 re separated by 6 A in both the oxidized and reduced forms of the protein.

184 ce mass spectrometry allows the oxidized and reduced forms of the proteins to be distinguished.

185 quantum chemical models of the oxidized and reduced forms of the proteins, based upon both isolated

186 Resonance Raman data of the oxidized and reduced forms of the R481L mutant indicate that the muta

187 The reduced forms of the redox cofactors, NAD(H) and NADP(H)

188 nd by the concentrations of the oxidized and reduced forms of the redox couple.

189 eme group in oxidized, reduced, and CO-bound reduced forms of the Rhodospirillum rubrum CO oxidation

190 ion of the mixed-valence (i.e., two-electron reduced) form of the enzyme with dioxygen.

191 ligand charge-transfer excited state and the reduced form of these compounds do not inject electrons

192 -N(3)(-) complexes in oxidized and substrate-reduced forms of these enzymes.

193 Reaction of oxygen with reduced forms of these modified enzymes in the absence o

194 ing cells in the root meristem, in which the reduced forms of these two species are favored.

195 In addition, only the reduced form of thioredoxin activated NF-kappaB, whereas

196 to compare backbone dynamics of oxidized and reduced forms of this 414-residue metalloenzyme via hydr

197 2466c allowing the release of the activated, reduced form of TP053.

198 o a rate-limiting electron transfer from the reduced form of TPQ (p-aminohydroquinone form) to dioxyg

199 copper-associated water molecule to form the reduced form of TPQ (TPQ(red)), followed by facile oxida

200 The reduced form of Trx suppresses the serum-free-induced hy

201 The reoxidations of two chemically distinct reduced forms of TTQ were studied, a quinol (O-quinol) g

202 he ET reactions from two chemically distinct reduced forms of TTQ were studied: an O-quinol form that

203 chain, and recent evidence suggests that the reduced form of ubiquinone (QH2) may play a second role

204 Recent evidence suggests that the reduced form of ubiquinone (ubiquinol) may also function

205 Inducer binding for both oxidized and reduced forms of V52C was comparable to wild-type lac re

206 lotoxin did not affect cytotoxicity, and the reduced form of wild-type CdtA exhibited a statistically

207 VTMCD studies show that the CO-bound reduced forms of wild-type, H77Y, and C75S contain low-s

208 he low-temperature photoproducts of CO-bound reduced forms of wild-type, H77Y, and C75S CooA.

209 resolved XPS measurements suggest that these reduced forms of Y and Zr exist only within the first fe