ライフサイエンスコーパス: reductase

1 ADPH to glutathione reductase or thioredoxin reductase.

2 but via conversion of nitrite by the nitrate reductase.

3 t likely caused by S-nitrosylation of aldose reductase.

4 e reductase, and one had nitrate and nitrite reductase.

5 DPH-dependent CDP-3-C-methyl-6-deoxyhexose 4-reductase.

6 he subunit b of the menaquinone:cytochrome c reductase.

7 ty but not the activity of NADH-ferricyanide reductase.

8 calized 3-hydroxy-3-methylglutaryl (HMG) CoA reductase.

9 d by the FMN domain of NADPH-cytochrome P450 reductase.

10 oyltetrahydropterin synthase and sepiapterin reductase.

11 been hampered by the lack of an Ngb-specific reductase.

12 pression of the p53-inducible ribonucleotide reductase.

13 choconstriction, S-nitrosoglutathione (GSNO) reductase.

14 how encodes an EDEM2/3-associated disulphide reductase.

15 phosphoenolpyruvate carboxylase and nitrate reductase.

16 osystem 1 complex, itself also an NADPH oxio-reductase.

17 d reoxidation to N(tz) ADP(+) by glutathione reductase.

18 doxins (Trxs) via a ferredoxin-dependent Trx reductase.

19 losis is a short-chain alcohol dehydrogenase/reductase.

20 s involving non-proton-pumping plastoquinone reductases.

21 pha-bromoesters using flavin-dependent 'ene'-reductases.

22 ng the mechanism of flavodiiron nitric oxide reductases.

23 ghts regarding the mechanism of nitric oxide reductases.

24 ymes, such as respiratory heme-copper oxygen reductases.

25 ght other short-chain alcohol dehydrogenases/reductases.

26 Carbonyl Reductase 1 (CBR1) is a ubiquitously expressed cytosolic

27 rolled predominantly by S-nitrosoglutathione reductase 1 (GSNOR1) which turns over the natural NO don

28 ic thioredoxin system, driven by thioredoxin reductase 1 (TrxR1 or TXNRD1).

29 Thioredoxin reductase 1 (TrxR1) is a selenocysteine-containing prote

30 in 2 (Prx2)/thioredoxin 1 (Trx1)/thioredoxin reductase 1 (TrxR1) network.

31 Pyrroline-5-carboxylate reductase 1 and 2 (PYCR1, PYCR2) were identified by mass

32 ed peptide derived from human fatty acyl-CoA reductase 1 in complex with heme exhibited a significant

33 statistics identified a higher prostaglandin reductase 2 expression at early reperfusion with RIPC th

34 wo subunits of NADPH-dependent dehydrogenase reductase 3 (DHRS3), which catalyzes the reduction of re

35 -sGC-cGMP signaling and reveal cytochrome b5 reductase 3 as the first identified physiological sGC he

36 Mechanistically, we show that cytochrome b5 reductase 3 directly reduces oxidized sGC required for N

37 mooth muscle cells reveal that cytochrome b5 reductase 3 expression and activity is critical for NO-s

38 tein-protein complexes between cytochrome b5 reductase 3, also known as methemoglobin reductase, and

39 lications of SD may be contributed by 5alpha-reductase (5alphaR), the rate-limiting enzyme in the con

40 In this brief report, dehydrogenase/reductase 9 (DHRS9) is identified as a robust marker of

41 63, heme oxygenase-1 (HMOX1), and biliverdin reductase A (BLVRA) showed robust changes following trau

42 Methionine sulfoxide reductase A (MsrA) is an enzyme involved in redox balanc

43 rgeting the antioxidant methionine sulfoxide reductase A to modulate liposarcoma cell survival and AS

44 utase (SOD2), catalase, methionine sulfoxide reductase A, and the 20S proteasome subunits PSMB5 and a

45 Finally, the alkyl hydroperoxide reductase, a primary scavenger of endogenous hydrogen pe

46 daI have predicted hydratase and dioxygenase reductase activities, respectively.

47 g to low chlorophyll but high ferric-chelate reductase activity and coumarin release.

48 blast cells showed deficient ferredoxin NADP reductase activity and mitochondrial dysfunction evidenc

49 Of note, it decreased NADH-ubiquinone reductase activity but not the activity of NADH-ferricya

50 CSA13 inhibited colonic HMG-CoA reductase activity in an FPRL1-dependent manner.

51 assay demonstrated that HCF222 has disulfide reductase activity in vitro.

52 d that LND inhibits the succinate-ubiquinone reductase activity of respiratory complex II without ful

53 ss-link caused a >/=95% loss of cytochrome c reductase activity that was reversible with DTT treatmen

54 es a rhodanase-like protein that shows As(V) reductase activity when expressed in Escherichia coli.

55 transcript levels, as well as ferric chelate reductase activity, and is causal for a portion of the o

56 The increased aldose reductase activity, higher sorbitol content and less acc

57 CcoNOP exhibited oxygen reductase activity, indicating that the cofactors (hemes

58 ropionate-CoA ligase (PrpE) and acryloyl-CoA reductase (AcuI) as the key enzymes involved and through

59 In many bacteria, a dedicated peroxiredoxin reductase, alkyl hydroperoxide reductase subunit F (AhpF

60 l gene, nirS (encoding cytchrome-cd1 nitrite reductase), along the salinity gradient of San Francisco

61 methanogens is mediated by methyl-coenzyme M reductase, an enzyme that is also responsible for the ut

62 The effector proteins, alkyl hydroperoxide reductase and acetyl-CoA acetyltransferase, recognizing

63 The cascade process is catalyzed by an ene-reductase and an alcohol dehydrogenase.

64 increase in ROS production and augmented GSH reductase and antioxidant regulator NRF2 activity, but d

65 O2 as well as membrane-bound heterodisulfide reductase and cytochromes.

66 n catalyzed by the drug target dihydrofolate reductase and established that protonation at N5 of H2F

67 ulates the expression of the plastid nitrite reductase and genes involved in the subsequent incorpora

68 idine residues in the key proteins in aldose reductase and heat-shock protein-70 within living cancer

69 ting in protein unfolding, inhibition of PDI reductase and isomerase activity in vitro and in vivo, a

70 Recombinant Chlamydomonas GPD2 showed both reductase and phosphatase activities in vitro and it can

71 We hypothesize that the reductase and phosphatase activities of PSP-GPD multidom

72 holesterol, resist GGpp-induced release from reductase and remain sequestered in the ER to block redu

73 It inhibits ribonucleotide reductase and reversibly arrests cells in S phase.

74 ctures of the Vitis vinifera dihydroflavonol reductase and SbCCR1, residues threonine-154 and tyrosin

75 tor of 3-hydroxy-3-methyl-glutaryl (HMG)-CoA reductase and the N-bisphosphonate zoledronic acid monoh

76 nd calcium levels along with the glutathione reductase and thioltransferase enzyme activities.

77 delivers nitrate to the respiratory nitrate reductase and transfers the product, nitrite, to the per

78 ntified genes encoding the subsequent 4-HPAA reductase and tyrosol:UDP-glucose 8-O-glucosyltransferas

79 cally characterized three leucoanthocyanidin reductases and two anthocyanidin reductases from P. nigr

80 oid isomerase, the SH3 domain, dihydrofolate reductase, and cytochrome c, where the transparent windo

81 milar to that in hemerythrin, ribonucleotide reductase, and methane monooxygenase, all of which can b

82 ined genes for both nitrate and nitric oxide reductase, and one had nitrate and nitrite reductase.

83 b5 reductase 3, also known as methemoglobin reductase, and oxidized sGC.

84 NADPH-cytochrome P450 reductase, biliverdin reductase, and thioredoxin reductase, resulting in a con

85 Anthocyanidin reductase (ANR) transcripts, the enzyme responsible for

86 Antibodies against HMG-CoA reductase apparently provoke SINAM.

87 hway key enzyme, adenosine 5'-phosphosulfate reductase (APR, EC 1.8.99.2), was significantly higher i

88 Our recent studies indicate that aldose reductase (AR) inhibitors such as fidarestat inhibit CRC

89 nt and variants in the gene encoding HMG-CoA reductase are associated with reductions in both the con

90 the bacterium synthesizes succinate:quinone reductase as part of its respiratory chain, whereas unde

91 hat two isolates held genes encoding nitrate reductase as the only dissimilatory N-oxide reductase, o

92 We demonstrate that FATTY ACYL-COA REDUCTASE (AsFAR) plays an essential role in the reprodu

93 Tfu-FNO is likely to act in vivo as an F420 reductase at the expense of NADPH, similar to its counte

94 l metabolism proteins such as PCSK9, HMG-CoA reductase, ATP citrate lyase, and NPC1L1.

95 :aa3 consists of a menaquinone:cytochrome c reductase (bc1 ) and a cytochrome aa3 -type oxidase.

96 Our results indicated that reductase becomes destabilized in the absence of UBIAD1,

97 glutathione reductase, NADPH-cytochrome P450 reductase, biliverdin reductase, and thioredoxin reducta

98 (Hpx) and Hpt and in up-regulated biliverdin reductase (BLVRA) gene expressions.

99 G20210A (FII), and methylenetetrahydrofolate reductase C677T.

100 roaerophilic conditions, the quinol:fumarate reductase can be utilized.

101 Our data suggest that aldose reductase can compensate for the loss of GLO1.

102 Carboxylic acid reductases (CARs) catalyze the reduction of a broad rang

103 t, ascorbic acid and the enzymes glutathione reductase, catalase, ascorbate peroxidase and superoxide

104 In this work, cytochrome c reductase (CcR) biofunctionalized self assembled monolay

105 Cinnamoyl-coenzyme A reductase (CCR) catalyzes the reduction of hydroxycinnam

106 Cinnamoyl-CoA reductase (CCR), an enzyme central to the lignin biosynt

107 L3 was shown to interact with geranylgeranyl reductase (CHLP), an enzyme of terpene biosynthesis that

108 on, mutations in genes encoding the chlorate reductase clrABC, predicted molybdopterin cofactor chape

109 etallireducens uses the class II benzoyl-CoA reductase complex for this reaction.

110 th the ER membrane protein vitamin K epoxide reductase complex subunit 1 variant 2 (VKORC1v2).

111 f the Bacillus C-methyltransferase and the 4-reductase confirmed their involvement in the formation o

112 s supported the hypothesis that each N-oxide reductase could provide a selectable benefit on its own,

113 separately co-expressed with cytochrome P450 reductase (CPR) in insect Spodoptera frugiperda (Sf9) ce

114 Cytochrome P450-reductase (CPR) is a versatile NADPH-dependent electron

115 Cytochrome P450 reductase (CPR) is the redox partner for most human cyto

116 cades with other enzymes, including carbonyl reductases (CREDs), hydrolases and monoamine oxidases (M

117 in 3-dioxygenase (F3H) and dihydroflavonol-4-reductase (DFR) in leaves, whereas a bHLH transcription

118 Dehydroascorbate reductase (DHAR) is a key enzyme involved in the recycli

119 he functional importance of dehydroascorbate reductases (DHARs) in interactions between ascorbate and

120 7-Dehydrocholesterol reductase (DHCR7) is the terminal enzyme of cholesterol

121 Dihydrofolate reductase (DHFR) is a key enzyme to regulate folate meta

122 iated by Plasmodium falciparum dihydrofolate reductase (DHFR) to two related inhibitors-pyrimethamine

123 P)-tagged bacterial-chromosome dihydrofolate reductase (DHFR) transgene can be visualized in a living

124 hymidylate synthase (TYMS) and dihydrofolate reductase (DHFR), as well as the components of the DNA r

125 ong-lived reference protein, a dihydrofolate reductase (DHFR).

126 esistance for Escherichia coli dihydrofolate reductase (DHFR).

127 racterizing fusion proteins of TxtE with the reductase domain of CYP102A1 (P450BM3, BM3R).

128 ytic cycle of Escherichia coli dihydrofolate reductase (ecDHFR) is whether the Met(20) loop is dynami

129 mutations in KDSR (3-ketodihydrosphingosine reductase), encoding an enzyme in the ceramide synthesis

130 ive feedback between dATP and ribonucleotide reductase ensures tight control of dNTP concentration.

131 igher levels of malondialdehyde, glutathione reductase enzyme activity, and calcium levels, which wer

132 It belongs to the 'RED' family of reductases, epimerases and dehydrogenases.

133 IAD1 deficiency and SCD-associated UBIAD1 on reductase ERAD and cholesterol synthesis.

134 establish UBIAD1 as a central player in the reductase ERAD pathway and regulation of isoprenoid synt

135 o-Golgi transport enables UBIAD1 to modulate reductase ERAD such that synthesis of nonsterol isopreno

136 indicate that UBIAD1-mediated inhibition of reductase ERAD underlies cholesterol accumulation associ

137 , an SCD-associated UBIAD1 variant inhibited reductase ERAD, thereby stabilizing the enzyme and contr

138 se and remain sequestered in the ER to block reductase ERAD.

139 VioA belongs to the glutathione reductase family 2 of FAD-dependent oxidoreductases acco

140 ized by different ferredoxin-dependent bilin reductases (FDBRs): PPhiB is synthesized by HY2, whereas

141 Ferredoxin reductase (FDXR), a target of p53, modulates p53-depende

142 genases, ferredoxins, and ferredoxin-NADP(+) reductases (FNR) are redox proteins that mediate electro

143 ive mechanism to thioredoxin and thioredoxin reductase for Prx2 recycling.

144 y, and it involves branching and alternative reductases for specific intermediates.

145 coli through interactions with the fumarate reductase (Frd) electron transport complex.

146 In addition, we identify the E. coli flavin reductase Fre, which is related to the dehydrogenase dom

147 archaeal strain to produce methyl-coenzyme M reductase from unculturable anaerobic methanotrophs for

148 thocyanidin reductases and two anthocyanidin reductases from P. nigra involved in catalyzing the last

149 m and substrate specificity of cinnamoyl-CoA reductases from sorghum (Sorghum bicolor), a strategic p

150 Nevertheless, the widespread quinone oxido-reductases from the cytochrome bc family limit the amoun

151 thioredoxins (Trxs), and an Fd-dependent Trx reductase (FTR), the Fd-FTR-Trxs system, which links red

152 uld correspond to NO location in the nitrite-reductase function of Ngb.

153 nd GDP-4-keto-6-deoxymannose 3,5-epimerase-4-reductase (FX or tissue specific transplantation antigen

154 nd GDP-4-keto-6-deoxymannose 3,5-epimerase-4-reductase (FX or tissue specific transplantation antigen

155 e characterized the diversity of the nitrite reductase gene (aniA), the factor H-binding protein gene

156 tion, we generated a knockout in the nitrate reductase gene (NR-KO) of the model pennate diatom Phaeo

157 the upstream promoter region of the nitrate reductase gene, NIA1, and physically interact under cont

158 ition, DnrF induced the expression of the NO reductase genes (norCB), which promote NO consumption.

159 arise between the presence of known N-oxide reductase genes and phenotypic features, bacteria able t

160 ion of a double bond in geranial by geranial reductase GER1 to give (S)-beta-citronellal.

161 AD(P)H dehydrogenase, quinone 1, glutathione reductase, glutamate-cysteine ligase catalytic subunit,

162 Guanosine-5'-monophosphate reductase (GMPR) catalyzes the reduction of GMP to IMP a

163 te that the gene for guanosine monophosphate reductase (GMPR) is a direct MITF target, and that the p

164 Here, we establish that S-nitrosoglutathione reductase (GSNOR), a major protein denitrosylase, provid

165 NO-metabolizing enzyme, S-nitrosoglutathione reductase (GSNOR), which exhibit enhanced S-nitrosylatio

166 nations of gene knockout, including arsenate reductase (HAC1), gamma-glutamyl-cysteine synthetase (ga

167 alcohol oxidation activities of human Aldose reductase (hAR).

168 (SRP) or anti-3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) antibodies (Abs), and the titer of the

169 riants in the 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) gene.

170 avastatin, hydroxymethylglutarate coenzyme-A reductase (HMGCR), was found to be over-expressed in all

171 rate-limiting enzyme in the pathway, HMG-CoA reductase (HMGCR).

172 Human ribonucleotide reductase (hRR) is crucial for DNA replication and maint

173 (S)-carbonyl reductase II (SCRII) from Candida parapsilosis is a shor

174 NQO1 and TRXR1 are important host reductases implicated in the regulation of inflammation

175 Inhibition of aldose reductase in GLO1(-/-) cells is associated with an incre

176 first identified physiological sGC heme iron reductase in vascular smooth muscle cells, serving as a

177 ed gene ahpC, encoding an alkylhydroperoxide reductase, independently of H2O2 A conserved cysteine re

178 The enoyl reductase InhA, responsible for synthesis of essential m

179 e time-dependent inhibition of the enoyl-ACP reductase InhA.

180 by cholesterol supplementation and HMG Co-A reductase inhibition.

181 ity of mature gametocytes to the glutathione reductase inhibitor and redox cycler drug methylene blue

182 oethanol and was enhanced by the thioredoxin-reductase inhibitor auranofin.

183 hda(+) strains exposed to the ribonucleotide reductase inhibitor hydroxyurea.

184 ([S]-LIP), that are loaded with the HMG-CoA reductase inhibitor simvastatin [S], were evaluated in t

185 tially rescued by treatment with the HMG-CoA reductase inhibitor simvastatin.

186 thesis inhibitor) and auranofin (thioredoxin reductase inhibitor) induces oxidative burst, mitochondr

187 nfluence of hydroxymethylglutaryl-coenzyme A reductase inhibitors (also known as statins) on colorect

188 ydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors (statins) have been the main therap

189 Hydroxy-methyl-glutaryl-coenzyme A (HMG-CoA) reductase inhibitors or statins are well tolerated, but

190 HMG-CoA reductase inhibitors such as statins are cholesterol-red

191 atins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) are an important group of hypolipi

192 atins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors), commonly prescribed in the primar

193 CoA (3-hydroxy-3-methylglutaryl-coenzyme A) reductase inhibitors, are drugs with multiple properties

194 PH patients who failed the therapy of 5alpha-reductase inhibitors.

195 ,e]azepines has highlighted the use of imine reductase (IRED) and omega-transaminase (omega-TA) bioca

196 NADPH-cytochrome P450 reductase is a multi-domain redox enzyme which is a key

197 ess, suggesting that the alkyl hydroperoxide reductase is an important regulator of redox homeostasis

198 the catalytic cycle of E. coli dihydrofolate reductase is tetrahydrofolate (THF) product release, whi

199 The enzyme, glutathione reductase, is highly specific to glutathione.

200 ing enzyme of dNTP synthesis, ribonucleotide reductase, is inhibited by endogenous levels of deoxyATP

201 ue pair of ferredoxin and ferredoxin-NADP(+) reductase isoforms.

202 Leucoanthocyanidin reductase (LAR) has been shown to convert leucocyanidin

203 Transcripts of leucoanthocyanidin reductase (LCR), which generates catechin, could not be

204 n of the unsaturated lactone; and the ferric-reductase-like enzyme RbtH, which regioselectively reduc

205 Methyl-coenzyme M reductase (MCR) is the key enzyme of methanogenesis and

206 Methyl-coenzyme M reductase (MCR), found in strictly anaerobic methanogeni

207 The methionine sulfoxide reductase (MSR) enzyme converts MetSO back to the reduce

208 Methionine sulfoxide reductase (MSR) enzyme converts MetSO back to the reduce

209 esidues is catalyzed by methionine sulfoxide reductases (Msrs).

210 h effects on 1-CM, methylenetetrahydrofolate reductase (MTHFR) 677C>T, rs1801133, and phosphatidyleth

211 1298A > C, of the methylene-tetrahydrofolate reductase (MTHFR) gene, an enzyme essential in DNA synth

212 Methylenetetrahydrofolate reductase (MTHFR) generates methyltetrahydrofolate for m

213 sociation with the methylenetetrahydrofolate reductase (MTHFR) genotype.

214 wild-type Columbia-0 (Col-0) and the nitrate reductase mutant nia1nia2.

215 fate transporter mutant strain and a sulfite reductase mutant strain are fully virulent.

216 orm of the Cu4S active site of nitrous oxide reductase (N2OR) that is observed in single turnover of

217 atalase, glutathione synthetase, glutathione reductase, NADPH-cytochrome P450 reductase, biliverdin r

218 s electrons through the mycothiol/mycothione reductase/NADPH pathway to activate TP053, preferentiall

219 port that DnrF selectively repressed nitrate reductase (nap) genes, preventing further NO formation.

220 ning subunit NarI of the respiratory nitrate reductase NarGHI as proteins that interact with HemW.

221 with the highly similar respiratory nitrate reductase NarGHI, which has a relatively much lower affi

222 HMG Co-A reductase negatively regulates eNOS, and the PLD2-defici

223 , an NO. dioxygenase (NOD), and NorV, an NO. reductase (NOR).

224 monia monooxygenase (amoA) and nitrous oxide reductase (nosZ) genes, mediating oxidation of ammonia a

225 n the denitrification pathway, nitrous oxide reductase (nosZ).

226 jor mechanism of NO synthesis is via NITRATE REDUCTASE (NR), an enzyme of nitrogen assimilation [5].

227 undance of ribosomal proteins and nucleotide reductase NrdEF was observed in post-infection samples c

228 tly, a plastid-localized NADPH-dependent Trx reductase (NTR) with a joint Trx domain, termed NTRC, wa

229 n assigned as an NADPH-dependent thioredoxin reductase (NTR).

230 tion of a halide and constitute the terminal reductases of a short electron transfer chain.

231 gulator for the enzyme organic hydroperoxide reductase (Ohr).

232 reductase as the only dissimilatory N-oxide reductase, one contained genes for both nitrate and nitr

233 lerated, ER-associated degradation (ERAD) of reductase, one of several mechanisms for feedback contro

234 The 2-methylene-furan-3-one reductase or Fragaria x ananassa Enone Oxidoreductase (F

235 ione (GSH) by supplying NADPH to glutathione reductase or thioredoxin reductase.

236 The Arabidopsis reductase ornithine cyclodeaminase/mu-crystallin, alias

237 Here we show that the fumarate reductase Osm1, which facilitates electron transfer from

238 nsferred through a ferredoxin and ferredoxin reductase pair.

239 symporter NasA from the assimilatory nitrate reductase pathway, support that NarK1 functions as a nit

240 is via FPRL1-dependent modulation of HMG-CoA reductase pathway.

241 ER membranes triggers release of UBIAD1 from reductase, permitting its maximal ERAD and ER-to-Golgi t

242 uster genes, we determined that the putative reductase PfmaG and the PKS are sufficient for the synth

243 rent energetic niches, express nitrous oxide reductase, potentially acting as a global sink for the g

244 system in conjunction with the dihydrofolate reductase protein-fragment complementation assay in Sacc

245 Pyrroline-5-carboxylate reductase (PYCR) is the final enzyme in proline biosynth

246 chia coli Complex II homolog quinol:fumarate reductase (QFR, FrdABCD) catalyzes the interconversion o

247 hytochrome photoreceptor, and ribonucleotide reductase R2 illustrate the power and versatility of thi

248 Organic hydroperoxide reductase regulator (OhrR) in bacteria is a sensor for o

249 membrane-associated flavoprotein ferrodoxin reductase required for electron transport from NADPH to

250 eme-depleted, catalytically inactive nitrate reductase, restoring its nitrate-reducing enzyme activit

251 ctase, biliverdin reductase, and thioredoxin reductase, resulting in a concomitant reduction of intra

252 a highly active ferredoxin/flavodoxin-NAD(+) reductase (Rnf) that catalyzes the irreversible reductio

253 ective rate-limiting enzymes, ribonucleotide reductase (RNR) and deoxycytidine kinase (dCK), via dist

254 ression of genes encoding the ribonucleotide reductase (RNR) and proteins that facilitate the use of

255 during activation of class I ribonucleotide reductase (RNR) beta subunits, which self-assemble dimet

256 Ribonucleotide reductase (RNR) is an essential iron-dependent enzyme th

257 Ribonucleotide reductase (RNR) is the only enzyme capable of de novo sy

258 The di-iron enzyme ribonucleotide reductase (RNR) uses a diferric-tyrosyl radical (Fe(III)

259 ich are strictly regulated by ribonucleotide reductase (RNR).

260 Ribonucleotide reductases (RNR) catalyze the reduction of nucleotides t

261 Ribonucleotide reductases (RNRs) catalyze the reduction of ribonucleoti

262 discovery in the chemistry of ribonucleotide reductases (RNRs) has been the identification of a diman

263 otide production catalyzed by ribonucleotide reductases (RNRs).

264 We recently found that the ribonucleotide reductase (RR) subunit M2 is potentially regulated by th

265 Eukaryotic class I ribonucleotide reductases (RRs) generate deoxyribonucleotides for DNA s

266 ly, mycobacterial short chain dehydrogenases/reductases (SDRs) within family TIGR03971 contain an ins

267 lines under-expressing monodehydroascorbate reductase showed a slight decrease in degradation produc

268 hydride transfer step in human dihydrofolate reductase shows that both the participation of the prote

269 ortex characterized by high levels of aldose reductase, sorbitol and endogenous fructose.

270 peroxiredoxin reductase, alkyl hydroperoxide reductase subunit F (AhpF), catalyzes the rapid reductio

271 Q is a newly identified methionine sulfoxide reductase system found in bacteria, which appears to be

272 I nitroreductase (TbNTR) or cytochrome P450 reductase (TbCPR) dependent prodrugs that, following act

273 A C-terminal reductase, TclS, can optionally act on the substrate pep

274 e bo3 is a respiratory proton-pumping oxygen reductase that is a member of the heme-copper superfamil

275 OsHAC4 is an As(V) reductase that is critical for As(V) detoxification and

276 variant known to mimic inhibition of HMG-CoA reductase (the intended drug target) with the same lipid

277 -12 nrf operon encodes a periplasmic nitrite reductase, the expression of which is driven from a sing

278 holesterol, causing upregulation of HMG Co-A reductase, the rate-limiting enzyme in cholesterol synth

279 tins lower cholesterol by inhibiting HMG-CoA reductase, the rate-limiting enzyme of the metabolic pat

280 the superfamily of short chain dehydrogenase-reductases, the epimerase-active KR(0) domains from poly

281 lete study of a plant DHFR-TS (dihydrofolate reductase-thymidylate synthase) gene family that impleme

282 other ROs, oxyBAC did not require a specific reductase to function.

283 chrome bd-II oxidase synergized with nitrate reductases to drive luminal expansion, and both were req

284 the Escherichia coli trimethylamine N-oxide reductase (TorA) signal peptide in TatBC receptor bindin

285 by increased catalytic efficiency of aldose reductase toward hemithioacetal (product of glutathione

286 and by upregulation of HMG-CoA synthase and reductase transcription.

287 llular H2O2 levels by inhibiting thioredoxin reductase (TrxR) in cells expressing CRBN, causing accum

288 d NO sensitivity because the Trx/thioredoxin reductase (TrxR) system maintains thiol redox homeostasi

289 Steroid 5alpha-reductase type 3 congenital disorder of glycosylation (S

290 Vitamin K epoxide reductase (VKOR) is an essential enzyme for vitamin K-de

291 tudy in vitro to suppress expression of GSNO reductase, was decreased in hyperoxia-exposed pups.

292 efficient hydrogen-dependent carbon dioxide reductase when gaseous CO2 and H2 are placed under press

293 enhanced level of the encoded glutamyl-tRNA reductase, which catalyzes one of the rate-limiting step

294 , chloroplasts harbor an NADPH-dependent Trx reductase, which has a joint Trx domain at the carboxyl

295 biting 3-hydroxy-3-methylglutaryl coenzyme A reductase, which is a rate-limiting enzyme for cholester

296 In the presence of FMN, NADH, and flavin reductase, which reduces FMN to FMNH2 using NADH as the

297 that Rv2466c is a novel mycothiol-dependent reductase, which represents a mycoredoxin cluster of enz

298 Interaction of human biliverdin reductase with Akt/protein kinase B and phosphatidylinos

299 produce mammalian selenoprotein thioredoxin reductases with unsurpassed purity and yield.

300 hat co-occurrence of cld and a chloroxyanion reductase within a single organism is not necessary and