ライフサイエンスコーパス: reductive elimination

1 Ni(III) species that readily participate in reductive elimination.

2 ation and turnover-limiting, propene-forming reductive elimination.

3 undergo high yielding aryl-CF3 bond-forming reductive elimination.

4 ediate wherein the stereodetermining step is reductive elimination.

5 merization and a carbon-halogen bond-forming reductive elimination.

6 selectivities for C(aryl)-X and C(aryl)-CF3 reductive elimination.

7 tion, beta-hydride elimination, and C-H bond reductive elimination.

8 Caryl-I reductive elimination over Caryl-CF3 reductive elimination.

9 -coordinate intermediate that undergoes slow reductive elimination.

10 se eventually leads to poly-naphthalenes via reductive elimination.

11 ArAr' intermediate, which then undergoes C-C reductive elimination.

12 cle involving rate-limiting C-C bond-forming reductive elimination.

13 ted Pd(III) dimer ultimately gives ArCl upon reductive elimination.

14 nometallic processes, oxidative addition and reductive elimination.

15 irecting group to facilitate the C(sp(3))-Ph reductive elimination.

16 -C bond, followed by migratory insertion and reductive elimination.

17 around the Au(I) center and a rate-limiting reductive elimination.

18 t directs oxidative addition and facilitates reductive elimination.

19 ound alkyls such as alkyne insertion and C-H reductive elimination.

20 Sonogashira coupling, amidopalladation, and reductive elimination.

21 2] rather than stepwise alkene insertion and reductive elimination.

22 rkovnikov vinyl sulfides via alkenyl-hydride reductive elimination.

23 dict a ~15 kcal/mol advantage for bimetallic reductive elimination.

24 which was shown to undergo diene-induced C-C reductive elimination.

25 Selectfluor, followed by heteroauration and reductive elimination.

26 geometry and electronic structure to induce reductive elimination.

27 CyPF-t-Bu do form in good yield and undergo reductive elimination.

28 ighly chemoselective aryl-CF(3) bond-forming reductive elimination.

29 hich establish the role of each metal during reductive elimination.

30 pared and observed to undergo selective C-Cl reductive elimination.

31 to Ni(III) , however, is required to trigger reductive elimination.

32 intermediate followed by transmetalation and reductive elimination.

33 solated and can afford product by bimetallic reductive elimination.

34 ide ligand prior to an inner-sphere SN2-type reductive elimination.

35 ting step from C-H oxidative addition to C-B reductive elimination.

36 on-rich diarylamines undergo faster rates of reductive elimination.

37 "upper" ring of the ligand slows the rate of reductive elimination.

38 ability of the amido complex with respect to reductive elimination.

39 , and directly delivers the intermediate for reductive elimination.

40 he most widespread are M-H homolysis and R-H reductive elimination.

41 alladium followed by C-C bond-forming [3,3']-reductive elimination.

42 s can undergo both C(aryl)-X and C(aryl)-CF3 reductive elimination.

43 lenging, turnover-limiting C(sp(3))-C(sp(3)) reductive elimination.

44 appears to be an isomerization prior to C-B reductive elimination.

45 eversible migratory insertion to give, after reductive elimination, 2,3-dihydropyridine products in g

46 AB(Me) forms the products from monomolecular reductive elimination, 2-Ph, 2-Ph-d(14), bibenzyl, and b

47 ts is determined in the subsequent competing reductive elimination and beta-hydride elimination steps

48 and leads to distinct steric control in the reductive elimination and beta-hydride elimination trans

49 etic transformation involving intramolecular reductive elimination and concomitant PMe3 elimination,

50 Formally a six-electron reductive elimination and oxidative addition, respective

51 he arene by Au(III) precedes product-forming reductive elimination and subsequent cycle-closing reoxi

52 Pd(II) chemistry includes transmetallation, reductive elimination and the field of C-H activation re

53 reduction, where two electrons come from H2 reductive elimination and the other two come from iron o

54 me ester to enable the C-C bond formation by reductive elimination, and intramolecular condensation o

55 with subsequent migratory alkyne insertion, reductive elimination, and intramolecular oxidative addi

56 ese complexes undergo clean C-O bond-forming reductive elimination, and the mechanism of this process

57 le-metal two-electron oxidative addition and reductive elimination are common fundamental reactions f

58 d iron(II)-SciOPP species that form prior to reductive elimination are identified, where both species

59 ide-bridged structures establishes binuclear reductive elimination as a viable mechanism for photogen

60 r the nitrogen extrusion followed by Au(III) reductive elimination as the key step.

61 In combination, the data implicate reductive elimination as the rate-determining step for b

62 system has been shown to favor aryl thiolate reductive elimination at elevated temperatures and in so

63 iarylplatinum(II) complex accelerates biaryl reductive elimination by a factor of 64,000.

64 The slow rate of reductive elimination causes the arylpalladium amido com

65 Several reductive elimination decomposition pathways of catalyst

66 monstrated protonolysis, oxidatively induced reductive elimination, deoxygenation, and elimination re

67 that undergoes at -90 degrees C accelerated reductive elimination enantioselectively and exclusively

68 Furthermore, the reductive elimination event was probed with (18) O-label

69 ies on precise timing of transmetalation and reductive elimination events.

70 ctron-donating ancillary NHC ligands undergo reductive elimination faster than complexes ligated by l

71 r and branched alkyl intermediates, although reductive elimination for the linear isomer is suggested

72 on of products resulting from subsequent B-C reductive elimination (for both indium and thallium).

73 dies of oxidatively induced C-C bond-forming reductive elimination from ((t)Bu(2)bpy)Pd(II)(Me)(2).

74 tion of aryl iodides into acid chlorides via reductive elimination from ((t)Bu3P)(CO)Pd(COAr)Cl.

75 Reductive elimination from 6 provides 2-benzylpyrrolidin

76 suggest this reaction is enabled by a facile reductive elimination from a cationic arylcopper(III) fl

77 We report a C-F reductive elimination from a characterized first-row ary

78 Our results implicate reductive elimination from a complex in which the dinucl

79 ign of specialized ligands, which facilitate reductive elimination from a destabilized metal center.

80 However, carbon-carbon bond reductive elimination from a limited number of Au(III) c

81 key C(alpha)-C(sp(3) ) bond is generated by reductive elimination from a palladium intermediate.

82 mpeting sp(3)-C-N and sp(3)-C-F bond-forming reductive elimination from a Pd(IV) fluoro sulfonamide c

83 terized low-valent Fe catalyst by controlled reductive elimination from a readily accessible Fe preca

84 The rates of reductive elimination from a series of arylpalladium cya

85 es are formed selectively through a stepwise reductive elimination from a tetraplatinum precursor and

86 The first systematic mechanism study of C-F reductive elimination from a transition metal complex is

87 action, including the first demonstration of reductive elimination from an arylpalladium isocyanate c

88 between the two aryl rings result in faster reductive elimination from Ar-Au(X)-Ar and lead to the p

89 es reveal that the electronic effects on the reductive elimination from arylpalladium cyanide complex

90 to Au(I), and remarkably fast Caryl-CF3 bond reductive elimination from Au(III) cations.

91 ry of a borane-catalyzed formal C(sp(3))-CF3 reductive elimination from Au(III) that accesses these c

92 parent amido ligand and the typically faster reductive elimination from complexes containing more bas

93 nd and conformational freedom on the rate of reductive elimination from diaryl-gold(III) species.

94 complex is reported to catalyze alkyl-alkyl reductive elimination from high-valent transition metal

95 For the first time, the C(sp(2))-N reductive elimination from isolated amidoaryl Pd(IV) com

96 The monometallic reductive elimination from mononuclear Au(III) complexes

97 es oxidatively induced Ar-CF(3) bond-forming reductive elimination from new Pd(II) complexes of gener

98 on, a result of the high kinetic barrier for reductive elimination from octahedral Ir(III) complexes.

99 ermore, rare examples of C(sp(3))-Br and -Cl reductive elimination from Pd(II) as well as transfer hy

100 oxidatively induced Aryl-CF(3) bond-forming reductive elimination from Pd(II).

101 heoretical investigation of the mechanism of reductive elimination from such dinuclear Pd(III) comple

102 of the mechanism of C(sp(3))-N bond-forming reductive elimination from sulfonamide-ligated Pd(IV) co

103 eta(2)-N2)] was synthesized by photochemical reductive elimination from the corresponding zirconium b

104 ier of 23.9 kcal/mol (363 K) for a concerted reductive elimination from the isolated, three-coordinat

105 igand-free nickel(II) salts, in which facile reductive elimination from the nickel metal center is in

106 vestigated and is proposed to involve direct reductive elimination from the octahedral Pd(IV) centers

107 indicated that the rate-determining step was reductive elimination from the palladium(II) species bea

108 Reductive elimination from the presented nickel(III) com

109 on is reversible, proving the possibility of reductive elimination from the species NacNacAlH(X).

110 The rates of reductive elimination from these C-bound fluoroenolate c

111 y, a section on Pd(IV) chemistry focusses on reductive elimination from these complexes (Section 5).

112 The mechanism of competing C-C bond-forming reductive elimination from these complexes has also been

113 We also show that aryl-aryl bond reductive elimination from these oxidized species is not

114 of Pd(II) to Pd(III) dimers and subsequently reductive elimination from these Pd(III) dimers (Section

115 Reductive elimination from this Pd(IV) species proceeds

116 microenvironment-catalyzed C(sp(3))-C(sp(3)) reductive elimination from transition metal complexes [A

117 s found to enable carbon-oxygen bond-forming reductive elimination from unstable alkyl palladium inte

118 mplexes are distinct from those on reductive reductive eliminations from arylpalladium alkoxo, amido,

119 reviously studied alkyl-alkyl and aryl-alkyl reductive eliminations from Au(III).

120 Subsequent reductive elimination furnishes the allyl-aryl coupled p

121 The ensuing reductive elimination furnishes the desired arylated pro

122 ce two protons into two hydrides, from which reductive elimination generates H2.

123 an 8pi insertion of tropone, and subsequent reductive elimination generates the [5-6-7] fused tricyc

124 Subsequent reductive elimination generates the product and a Pd(0)

125 Each Ni(III) undergoes separate, but fast reductive elimination, giving rise to Ni(I) species.

126 Concerted reductive elimination has been studied with 6a directly

127 s that nitrenes are not generated and thus a reductive elimination has occurred.

128 i.e. oxidative addition, transmetalation and reductive elimination, have been studied, and their rela

129 metalation, C-Br oxidative addition, and C-C reductive elimination in a model gold complex are shown.

130 roamides, and difluoroacetonitrile underwent reductive elimination in high yields.

131 iting insertion, by lowering the barrier for reductive elimination in the linear-selective pathway.

132 uced a nickel aryl hydride which can undergo reductive elimination in the presence of formaldehyde to

133 metallic reactions, i.e. oxidative addition, reductive elimination, insertion and elimination reactio

134 study highlights that irreversible C(aryl)-P reductive elimination is a feasible decomposition or act

135 Reductive elimination is accelerated by electron-donatin

136 the interplay between oxidative addition and reductive elimination is key for a potential catalytic c

137 mide], the energies for the regiocontrolling reductive elimination is predicted to be more in favor o

138 Fast C-F reductive elimination is proposed to occur from an aryl-

139 support the conclusion from experiment that reductive elimination is rate-determining and forms the

140 Interestingly, the reductive elimination is rate-determining for the major

141 It is suggested that the C-C bond-forming reductive elimination is the enantiodetermining step in

142 d similar enantioselectivities implying that reductive elimination is the stereodetermining step.

143 ring expansion of cyclobutanol followed by a reductive elimination) is found to be energetically more

144 fonamide ligand plays a crucial role for C-F reductive elimination, likely due to a kappa(3) coordina

145 oxidative addition, migratory insertion, and reductive elimination may lead to ample new opportunitie

146 An unprecedented concerted reductive elimination mechanism for benzoxazole formatio

147 with an oxidative addition/olefin insertion/reductive elimination mechanism for each regioisomeric p

148 reaction proceeds via an oxidative addition/reductive elimination mechanism involving a Ni(IV) inter

149 from [PhCu] by either an oxidative addition/reductive elimination mechanism or nucleophilic substitu

150 e it is tempting to invoke a transmetalation/reductive elimination mechanism similar to that proposed

151 The oxidative addition-reductive elimination mechanism via an unstable Cu(III)

152 provides direct experimental support for the reductive elimination mechanism.

153 tically with the standard three-centered C-C reductive elimination mechanism.

154 g more-sterically bulky amido groups undergo reductive elimination more slowly than complexes contain

155 arylpalladium parent amido complexes undergo reductive elimination much more slowly than the analogou

156 S(N)2; (ii) S(N)2'; (iii) oxidative-addition/reductive elimination (OA/RE) via an M(III) eta(3)-allyl

157 sm for all species is via oxidative addition/reductive elimination (OA/RE).

158 The experimental data suggest that reductive elimination occurs from cationic Pd(IV) fluori

159 These studies indicate that reductive elimination occurs readily for more nucleophil

160 group, and identified conditions under which reductive elimination occurs to form an Ar-F bond.

161 The reductive elimination occurs via an unconventional seven

162 ,6-trimethylphenyl (Mes)) to 1-Ph results in reductive elimination of 1 equiv of bibenzyl (PhCH(2)CH(

163 tinum(IV) complex underwent highly selective reductive elimination of 2-fluoromesitylene upon heating

164 try, we examined the chemoselectivity in the reductive elimination of a dinuclear Pd(III) complex bea

165 These enzymes catalyze the reductive elimination of a halide and constitute the ter

166 roethenes and chlorethanes by catalyzing the reductive elimination of a halogen.

167 ron-sulfur cluster is directly involved in a reductive elimination of a hydroxyl group.

168 e beta-hydride elimination, (4) irreversible reductive elimination of AcOH, and (5) aerobic oxidation

169 Reductive elimination of alkane followed by alkene bindi

170 The rate of reductive elimination of an amido complex based on a Bre

171 Computational studies indicate that the reductive elimination of an arylnitrile from Pd(II) occu

172 with electron-donating substituents undergo reductive elimination of aromatic nitriles faster than c

173 was found to be consistent with the rates of reductive elimination of benzene from a series of isoele

174 In contrast to the reductive elimination of benzylamines from bisphosphine-

175 izes the uranium center in 3-Ph and prevents reductive elimination of bibenzyl.

176 with a process that proceeds by way of 3,3'-reductive elimination of bis(eta(1)-allyl)palladium inte

177 The proposed mechanism of exchange involves reductive elimination of Bu(t)3SnH from 1 to afford vaca

178 Reductive elimination of carbon-carbon bonds occurs in n

179 a-Si elimination but either ethylene loss or reductive elimination of cis-disposed aryl and SiMe3 moi

180 arene C-H bond; rather, it appears to be the reductive elimination of cyclohexane during the hydrogen

181 Selective reductive elimination of ethane (Csp(3)-Csp(3) RE) was o

182 rgoes both pyridine (py) loss as well as the reductive elimination of H(2).

183 key in the binding and activation of N2 via reductive elimination of H2 .

184 1,3,5-benzenetricarboxylate) via bimetallic reductive elimination of H2 from putative [M(IV)6(mu3-O)

185 Thus, substrate binding causes reductive elimination of H2 that formally reduces the me

186 as the key catalytic intermediate formed by reductive elimination of H2 with concomitant N2 binding,

187 ion that drives the re/oa equilibrium toward reductive elimination of H2 with N2 binding/reduction.

188 ride complexes, the dominant photoprocess is reductive elimination of H2.

189 propose a mechanism involving the homolytic reductive elimination of hydrogen.

190 e-dependent membrane proteins catalyzing the reductive elimination of iodide from iodothyronines thro

191 I)-Me complex (DPEphos)RhMeI2 (1) results in reductive elimination of MeI.

192 exes of these ligands do not form or undergo reductive elimination of monoarylamines.

193 (4) hydrolysis of the acetyl group, and (5) reductive elimination of Pd(0), which regenerates the ca

194 Carbon monoxide enforces a bimolecular reductive elimination of PhSSPh from 3, yielding (IMes)(

195 conditions were employed to investigate the reductive elimination of RuPhos (2-dicyclohexylphosphino

196 A reductive elimination of S-nitrosocysteines using phosph

197 that the reaction does not occur via initial reductive elimination of SiH4, but rather by a metathesi

198 pe hydrogenation cycle with rate determining reductive elimination of the alkane.

199 In addition, the transition state for the reductive elimination of the aromatic nitrile is much di

200 onic structure of 2 and the mechanism of the reductive elimination of the benzene molecule in its rea

201 addition of the C-H bond in this mechanism, reductive elimination of the C-Si bond occurs to generat

202 The reaction involves the reductive elimination of the C4 hydroxyl group, using a

203 dly, its exposure to UV light affords, after reductive elimination of the entire PCO group, the unpre

204 rom Ni(0) species generated in situ from the reductive elimination of the highly reactive hydride int

205 was found to be inconsistent with the direct reductive elimination of the mixed Cl/OAc containing Pd(

206 resulting Cu(I) complex into the Ar-X bond, reductive elimination of the new sp(3) C-X bond, and fin

207 es and subsequent stereo- and regioselective reductive elimination of the product.

208 In this model, H2 is produced by reductive elimination of the two bridging hydrides of E4

209 FeMo-cofactor through a mechanism involving reductive elimination of two [Fe-H-Fe] bridging hydrides

210 to the one suggested by spectroscopy, with a reductive elimination of two hydrides just before nitrog

211 fin on the PdH Heck intermediate followed by reductive elimination of vinylarene; (c) reinsertion of

212 We report reductive eliminations of primary arylamines from a seri

213 tion, these compounds undergo reversible C-C reductive elimination offering a unique approach to cycl

214 l transformation of the compound by means of reductive elimination or other mechanisms and is therefo

215 chanisms involving either oxidative addition/reductive elimination or sigma-bond metathesis are disfa

216 onformational biasing element to promote C-C reductive elimination over an alternative C-N bond-formi

217 s are quantitative and heavily favor Caryl-I reductive elimination over Caryl-CF3 reductive eliminati

218 ated to a metal ion of possible relevance to reductive elimination/oxidation addition reaction chemis

219 We proposed a reductive elimination/oxidative addition (re/oa) mechani

220 thermodynamically and kinetically reversible reductive-elimination/oxidative-addition exchange of N2

221 action operates through an inner-sphere 3,3'-reductive elimination pathway, which is both rate-defini

222 transfer as opposed to an oxidative addition/reductive elimination pathway.

223 transformation follows an oxidative addition-reductive elimination pathway.

224 t on subtle conformational effects governing reductive elimination pathways from high-valent palladiu

225 species might be prevalent due to accessible reductive elimination pathways, remains undefined.

226 on at the alkyl group, indicating that these reductive eliminations proceed by a concerted pathway.

227 and additives, suggest that C-O bond-forming reductive elimination proceeds via initial carboxylate d

228 nd forming reaction occurs via a bimolecular reductive elimination process (devoid of transmetalation

229 ry to perform the difficult C-N bond-forming reductive elimination, producing a Ni(I) complex, which

230 g allyllithium intermediate to LPdAr(Br) and reductive elimination provide the 1,1-diarylprop-2-enes,

231 inant removal, such as (i) dechlorination by reductive elimination rather than hydrogenolysis and (ii

232 Rare cases of directly observed reductive elimination (RE) of methyl halides from Rh(III

233 (4H) is poised to bind and reduce N2 through reductive elimination (re) of the two hydrides as H2, co

234 The net 2e(-) reductive elimination reaction also occurs without a oxi

235 tent with a reaction that operates by a 3,3' reductive elimination reaction.

236 These products are not just the result of reductive elimination reactions but may also arise via r

237 In 2009, we reported C-halogen reductive elimination reactions from dinuclear Pd(III) c

238 an investigation of C(sp(3))-O bond-forming reductive elimination reactions from Pd(IV) complexes.

239 Kinetic studies of C-H bond coupling and reductive elimination reactions from the five-coordinate

240 the two metals is responsible for the facile reductive elimination reactions observed.

241 (III) species undergo transmetalation and/or reductive elimination reactions to form new C-C or C-het

242 ound impact on the chemoselectivity of these reductive elimination reactions.

243 clopropylcarbinyl)nickel complex, which upon reductive elimination releases the cyclopropane.

244 upling reactions, including C-C bond-forming reductive elimination, represents a significant challeng

245 (transmetalation --> oxidative addition --> reductive elimination), resulting in the isolation and c

246 Fast reductive elimination results in the formation of the hy

247 inversion), transmetalation (retention), and reductive elimination (retention).

248 The rates of reductive elimination reveal that complexes containing m

249 The reductive elimination selectivity varies dramatically as

250 -stage 'oxidative addition, transmetalation, reductive elimination' sequence, there are a number of f

251 lectivity during the selectivity-determining reductive elimination step of the related coupling of to

252 CPhos, effectively promotes the rate of the reductive elimination step relative to the rate of the u

253 ts inability to catalyze C-H silylation; the reductive elimination step to form the silylation produc

254 The reductive elimination step was investigated by DFT calcu

255 C-O bond-forming step (formally known as the reductive elimination step) to occur via a Ni(III) alkox

256 ) intermediate preceding the product-forming reductive elimination step.

257 been conducted to gain insights into the key reductive elimination step.

258 ugated alkenes involving a C(sp(3))-C(sp(3)) reductive elimination step.

259 d through studies of the transmetalation and reductive elimination steps of the reaction, including t

260 e elimination and facilitate transmetalation/reductive elimination steps.

261 ubstituted phenethylamines via a challenging reductive elimination that affords a quaternary carbon.

262 taining two ortho fluorines have barriers to reductive elimination that are approximately 5 kcal mol(

263 atic nitrile is much different from that for reductive eliminations that occur from most other arylpa

264 (-) and [Cu(III)](C6F5)(OPh) unstable toward reductive elimination to [Cu(I)](solvent) and PhO-C6F5.

265 de abstraction, migratory insertion, and C-F reductive elimination to achieve a net C-C bond construc

266 (III) complexes can undergo facile C(aryl)-P reductive elimination to afford phosphonium salts, which

267 cterized that is effective for H-transfer or reductive elimination to deliver alkenylated or pyridini

268 ching), alkyl halide oxidative addition, and reductive elimination to enable alkyl-alkyl fragment cou

269 h then undergoes transmetalation followed by reductive elimination to form a new sp(3)-sp(3) carbon-c

270 arylpalladium cyanide complexes that undergo reductive elimination to form arylnitriles.

271 ed Ni(II) complexes, upon oxidation, undergo reductive elimination to form carbon-halogen bonds.

272 While reductive elimination to form Fe(eta(6)-biphenyl)(SciOPP

273 m the silylation product is much slower than reductive elimination to form the alkene hydroarylation

274 he turnover-limiting step of the reaction is reductive elimination to form the C-N bond.

275 ickel-aryl intermediate and rate-determining reductive elimination to form the carbon-carbon bond.

276 IV) species, which then undergoes facile C-C reductive elimination to form the final product.

277 allow the direct observation of bimolecular reductive elimination to generate ethane and biphenyl, r

278 tive addition can be shown to be followed by reductive elimination to give an N- (or O-)borylated pro

279 1) decoordination of the protonated base and reductive elimination to give the BCB product and (2) pr

280 he PPh(3), undergoes migratory insertion and reductive elimination to give the diamination product an

281 the reactivity of the arene and changes from reductive elimination to pi-complexation for arenes bear

282 a vinylgold(III) intermediate that undergoes reductive elimination to provide the heterocyclic coupli

283 ergoes a second alkyne insertion followed by reductive elimination to yield pyrrole and a Ti(II) spec

284 oxide bond, followed by rate-determining C-H reductive elimination to yield the ether product.

285 ene (NHC) ligands were prepared that undergo reductive eliminations to form the alkyl-nitrogen bond o

286 be reversible while the methane elimination (reductive elimination) transition state controls rate an

287 Reductive elimination via ligand-bridged binuclear inter

288 an unsaturated pi-allyl complex followed by reductive elimination via transition state II.

289 Cu(III) eta(3)-allyl intermediate undergoes reductive elimination via two different transition state

290 aryl halide and C-N coupling with amine via reductive elimination was also probed using DESI-MS.

291 This tendency to undergo reductive elimination was exploited in the investigation

292 Reductive elimination was faster from complexes containi

293 Clean reductive elimination was observed for all compounds in

294 orine plays an essential role, followed by a reductive elimination where the C-C bond formation is co

295 th a number of problems, including difficult reductive elimination, which often leads to beta-hydride

296 Herein we present an N-N bond-forming reductive elimination, which proceeds via a mixed-valent

297 mit competing C(sp(3))-C(sp(2)) bond-forming reductive elimination, while the presence of Lewis acidi

298 ulated DeltaG() values for isomerization and reductive elimination with a series of sulfonamide deriv

299 reaction of D2 with the N2-bound product of reductive elimination would generate dideutero-E4 [E4(2D

300 the mass-selected Me(3)CuR(-) anions undergo reductive elimination, yielding both the cross-coupling