ライフサイエンスコーパス: redundancy

1 utagenesis is highly inefficient due to gene redundancy.

2 llular processes that were masked by genetic redundancy.

3 , 2, and 4 confirms this apparent functional redundancy.

4 levels of other isoforms provide functional redundancy.

5 hibit CARD11 activity with cooperativity and redundancy.

6 rallel architecture furnishes robustness via redundancy.

7 same set of GPCRs, which implies functional redundancy.

8 bination of embryonic defects and functional redundancy.

9 ein Report to address growing issues of data redundancy.

10 olecular basis for their observed functional redundancy.

11 consequences on cancer cells due to genetic redundancy.

12 fungal genera occurred at high phylogenetic redundancy.

13 s a quantitative estimate of initiation site redundancy.

14 be at the basis of their apparent functional redundancy.

15 ymers with a remarkable degree of functional redundancy.

16 edict current densities and chart functional redundancy.

17 ggesting a limited degree of multifunctional redundancy.

18 ty was a marginally significant predictor of redundancy.

19 ry mechanism and suggests partial functional redundancy.

20 ves that all databases exhibit some level of redundancy.

21 sults challenge the generality of functional redundancy.

22 ease in repetitiveness and rigidity, but not redundancy.

23 e primary and secondary CESAs, and some CESA redundancy.

24 omputational handicap and reduce information redundancy.

25 mains with phenotypes masked by lethality or redundancy.

26 tribute to enhancing GrC diversification and redundancy.

27 on largely supports the notion of functional redundancy.

28 al glucose homeostasis, with some functional redundancy.

29 ned in sponge microbiomes through functional redundancy.

30 tion for ionization among peptides, and mass redundancies.

31 etermined to what extent there is functional redundancy across ants, other invertebrate and vertebrat

32 Redundancy across selectively coupled modules, as we obs

33 onally, GeoChip analyses showed a functional redundancy across the toposequence, with genes related t

34 ults provide support for the hypothesis that redundancy aids in motor learning and that the redundant

35 The exploitation of asymmetric redundancies allows the separation of two BIRD functions

36 This functional redundancy allows limited fatty acid biosynthesis to occ

37 Due to the large redundancies among genomic sequences of individuals from

38 Yet, the possible redundancies among these different footprints have not y

39 Functional redundancy among factors and pathways underlies the impo

40 ion that was previously hidden by functional redundancy among homoeologs.

41 These findings identify functional redundancy among Kit-dependent hematopoietic lineages an

42 Nonetheless, the degree of redundancy among miRNAs, coupled with the promiscuity of

43 icate that although there is some functional redundancy among mitophagy receptors, efficient sequestr

44 pletely defined, and the level of functional redundancy among subsets of these proteins remains open

45 lier step of endocytic uptake, and potential redundancy among the three separate genes that encode ma

46 Redundancy analyses revealed that in the summer, urban a

47 y information, so our study utilized partial redundancy analysis (RDA) and spatially lagged regressio

48 onmental gradients (constrained variation in redundancy analysis = 68%-76%) - particularly oxygen and

49 Redundancy analysis indicated the unexpected results tha

50 Redundancy analysis of the invertebrate community showed

51 w how the use of phylogenetic distance based redundancy analysis provides ecological interpretation o

52 Redundancy analysis revealed that community variation of

53 Redundancy analysis showed significant correlations betw

54 However, redundancy analysis showed that changes in microbial com

55 e linear regression model and distance-based redundancy analysis were used to disentangle the relativ

56 urological specialty care interface to avoid redundancies and other medical waste.

57 Both the resolution of these redundancies and the energetics of such systems depend o

58 overlapping substrates, they exhibit genetic redundancy and compensation, and pharmacological inhibit

59 es and to better understand their functional redundancy and diversification, we characterized single

60 velopment; however, cell-specific functions, redundancy and feedback mechanisms regulating bone growt

61 s resistance, among host genotypes may offer redundancy and generally limit the invasion potential of

62 nd cooling elements to regulate temperature, redundancy and incoherence in regulation generally sugge

63 ated by the complex in vivo milieu of factor redundancy and indirect effects.

64 Beyond redundancy and interplay, individual T3Es may interact w

65 However, genetic redundancy and lethality have made it challenging to def

66 issection of actin molecular function due to redundancy and neofunctionalization.

67 populations along with compounding issues of redundancy and plasticity raise intriguing questions abo

68 We present and discuss our hypothesis that redundancy and pluripotency evolved in tick salivary imm

69 ilies, and individual family members display redundancy and pluripotency in their action to ameliorat

70 c tool and enables graphical analysis of SAR redundancy and project progression.

71 This feature is often explained in terms of redundancy and regulatory flexibility, but it has remain

72 undamental questions about mechanisms of non-redundancy and resistance.

73 matin architecture arises through a blend of redundancy and specialization.

74 nteractions between daf-7 and tph-1 regulate redundancy and synergy among neurons in food encoding th

75 analysis and highlights the consequences of redundancy and synergy during information transmission,

76 gh previous studies have emphasized how such redundancy and the associated flexibility may play an im

77 ering variables for the minimization of data redundancy and the maximization of variable relevancy.

78 ffecting the egg cell, likely due to genetic redundancy and/or cross-regulation among the five RKD ge

79 eater integration across theories (to reduce redundancy) and greater emphasis on the circumstances un

80 rces is fragmented across the Web, with much redundancy, and has lacked a common standard of informat

81 as distinct entries in databases causes data redundancy, and misleads downstream analysis.

82 l species can achieve a degree of functional redundancy, and that their compensatory herbivory may pl

83 but their synaptic functions and mechanistic redundancy are not completely understood.

84 ed proteins exhibited substantial functional redundancy, as ectopic expression of either protein resc

85 sed on their sequence similarity, functional redundancy, as well as species and features of AGO-bound

86 1) the rare-disease assumption and 2) the no-redundancy assumption.

87 Several levels of functional redundancy at different scales of the bacterial metacomm

88 onfidence in existing measures of pollinator redundancy at the community level using visitation data,

89 nd reveals previously unidentified metabolic redundancy at the FBPase-catalysed reaction step of the

90 ised in drawing conclusions about functional redundancy based on a single environmental situation.

91 of stress-induced anxiety and the functional redundancy between AEA and 2-AG signaling in the modulat

92 In this study, we tested the functional redundancy between different SAMPs and how these domains

93 In this project, the redundancy between endoglin and vascular endothelial gro

94 een antigens driving population dynamics, or redundancy between functionally similar accessory ABTs,

95 across individual time steps, and we compute redundancy between genes by using a dynamical time warpi

96 Although redundancy between H2BE18 and H2BE19 ADP-ribosylation is

97 iltering is less effective when there is low redundancy between hypothesis tests and its benefit decr

98 Finally, we demonstrate functional redundancy between Ldb1 and Ldb2.

99 of dnapkcs-exo1- cells to PARPi, indicating redundancy between nucleases that initiate HR can drive

100 ted responses in plants, although functional redundancy between proteins could influence the results.

101 This confirms the existence of partial redundancy between SERK3 and SERK1 as well as the promot

102 Stx1 have been elusive due to the functional redundancy between Stx1 isoforms Stx1A and Stx1B and the

103 However, redundancy between the 19 mammalian Wnt proteins and 10

104 There is remarkable redundancy between the Cyclin-Cdk complexes that compris

105 ity are difficult to decipher as a result of redundancy between the family members.

106 is work, we seek to determine the functional redundancy between the kinase domains of the four major

107 findings support the existence of functional redundancy between the Y chromosome genes and their homo

108 ical roles, a pharmacological and functional redundancy between these canonical eCB signaling pathway

109 tes were excluded, indicating low functional redundancy between these groups.

110 1-1 ern2-1 phenotype demonstrates functional redundancy between these two transcriptional regulators

111 To understand the difference, or redundancy, between PMEIs, we used molecular dynamics (M

112 Consistent with this redundancy, both LjEin2a and LjEin2b are required for ne

113 and dermal DC subsets often show functional redundancy, but LCs are required for specific types of a

114 that MLL1/MLL2 collaboration is not through redundancy, but regulation of distinct pathways.

115 pathway unexpectedly bypasses its functional redundancy by exploiting both the nature of pathway flux

116 This result suggests that functional redundancy can further decrease when spatial variations

117 To reduce such redundancy, CD103(-/-) mice were crossed to mice (design

118 a certain extent, their substrate preference redundancies correlate with structural classes, thus lin

119 data based on maximum relevance and minimum redundancy criteria.

120 e benefits of a mass balance approach due to redundancy, data consistency, and transparency for optim

121 in the induction of pT(reg) cells and their redundancy during the development of oral tolerance.

122 nt levels of details to be obtained and data redundancy eliminated while keeping biologically interes

123 three proteins with such apparent functional redundancy exist in mammals.

124 odel highlights the importance of functional redundancies existing between the Apc proteins both in n

125 This redundancy explains the emergence of objective, classica

126 iological roles and the extent of functional redundancy following embryo implantation.

127 Although eukaryotes possess a number of redundancies for initiating and completing repair of mis

128 ctivity and connectivity revealed unexpected redundancy for a simple computation in the brain.

129 Our data further indicate limited redundancy for NSD family members in HPV-negative HNSCCs

130 We also uncover functional redundancy for somatic embryogenesis among other Arabido

131 To evaluate the specificity and redundancy for these cytokines, we quantified their glob

132 lyploid wheat; we also argue that functional redundancy has 'locked up' a wide range of phenotypic va

133 In contrast, extreme functional redundancy has evolved among expanded gene families oper

134 It has been suggested that this regulatory "redundancy" helps ensure reliable activation of gene exp

135 several important issues about mechanisms of redundancy, heterogeneity, biologic importance, and drug

136 .e., the spatial pattern of signal and noise redundancy/homogeneity across neurons), and does knowled

137 were reviewed and a number of trade-offs and redundancies identified.

138 protein family provides for some functional redundancy, important differences have been observed and

139 These data point toward possible redundancies in B-cell signaling/survival pathways, whic

140 genetic interactions can dissect functional redundancies in cellular networks.

141 We utilize redundancies in genotype patterns between neighboring lo

142 and states of individual muscles, resolving redundancies in joint actuation and lending insight into

143 The lack of redundancies in ribonucleotide repair in archaea perhaps

144 reduce image noise by exploiting information redundancies in the energy domain.

145 tic Analysis (LSA) was applied to remove the redundancies in the feature space.

146 rticle explores the functional diversity and redundancy in a bacterial metacommunity constituted of t

147 The level of genetic redundancy in a single-celled organism may thus reflect

148 However, their role and possible redundancy in ALK-driven lymphoma development in vivo ar

149 This partial response is consistent with redundancy in chemokine pathways and highlights the need

150 o validate the map's necessity we tested its redundancy in comparison with existing pathways, and to

151 on the biochemical functions of the cls gene redundancy in E. coli and other bacteria.

152 genes showed their functional divergence and redundancy in evolution.

153 gradely labelled colonic neurons, suggesting redundancy in function.

154 o degrade polysaccharides relies on apparent redundancy in functional traits and the high frequency o

155 lation could overcome the signalling pathway redundancy in GBM and, hence, promote tumour cell death.

156 Additionally, there appears to be functional redundancy in genera of CCRA providing cues to abalone,

157 essential genetic loci and demonstrate PRDM9 redundancy in humans.

158 in discovery probability when there is high redundancy in information between hypothesis tests.

159 Humans employ a high degree of redundancy in joint actuation, with different combinatio

160 ssect complex biological systems and genetic redundancy in microbial systems.

161 d plants, M. polymorpha exhibits low genetic redundancy in most regulatory pathways, with this portio

162 larity to known families, can help to reduce redundancy in motif databases and de novo prediction alg

163 Shapes suggesting functional redundancy in one environment can change, suggesting fun

164 ese data highlight an unappreciated level of redundancy in pathways that couple innate virus sensing

165 -based data formats do not fully exploit the redundancy in population sequencing nor take advantage o

166 red networks, indicating a higher functional redundancy in restored communities.

167 . japonicus While mutant analysis identified redundancy in several biosynthesis families, we found th

168 This redundancy in the ability of the two ERalpha-AFs to sepa

169 However, the importance of potential redundancy in the action of tribbles and how the differe

170 We suggest that this active redundancy in the bacitracin resistance network of B. su

171 Here, we demonstrate that the apparent redundancy in the CLV1 clade is in fact due to the trans

172 ingle-cycle infectivity assays, suggesting a redundancy in the contributions of jumping and intersegm

173 Furthermore, we show substantial redundancy in the control of key vocal parameters ex viv

174 Such redundancy in the cortical and machine signals is indica

175 Particular attention was given to removing redundancy in the data and normalizing across ligand div

176 We report that there is redundancy in the function of two innate immune cell sub

177 ringently required, likely due to functional redundancy in the latter.

178 tion of myelinated axons and reveals further redundancy in the mechanisms required for the formation

179 Second, there may be high functional redundancy in the methanogens with regard to methane pro

180 strates that EEEV exhibits a unique level of redundancy in the use of host factors in RNA replication

181 ncludes seven endoproteases with significant redundancy in their cleavage activity.

182 the setting of PARKIN knockdown, suggesting redundancy in their ubiquitin ligase roles.

183 Furthermore, the redundancy in this collection of plants allowed for the

184 Redundancy in this complex metabolic network renders the

185 Pseudomonas syringae, indicating functional redundancy in this large gene family.

186 North American EEEV exhibits a high level of redundancy in using host factors in replication complex

187 parsed into three data streams in which the redundancy information are identified and eliminated ind

188 TprK demonstrated remarkable variability and redundancy, intra- and interpatient, suggesting ongoing

189 iting the inherent particle movement and the redundancy introduced by the astigmatism.

190 How this redundancy is linked to in vivo function and how gene-sp

191 This redundancy is more extensive in recently formed polyploi

192 Moreover, redundancy is neither necessary nor sufficient to make p

193 use multiple pathways can be affected, while redundancy is observed for a single phenotype.

194 A similar, although not identical, redundancy is observed for LAP1 and LULL1, which serve a

195 Second, partial redundancy is recapitulated where INO80 alone, or ISW2 a

196 This redundancy is thought to be mediated, at least in part,

197 es between the isoforms, the extent of their redundancy is unclear.

198 AGO6-dependent DNA methylation revealed that redundancy is unexpectedly negligible in the genetic int

199 s pathogen, and the reason for this apparent redundancy is unknown.

200 The basis of this genetic redundancy is unknown.

201 expression cannot be explained by functional redundancy, is supported by active transcription and sho

202 Because of complex feedback interactions and redundancy, it has been difficult to define the portion

203 n in normal cells, but because of functional redundancy, it is absolutely required for this process i

204 The PIC also has a degree of redundancy, making it suitable for applications, such as

205 screen 52 substrates, providing a substrate redundancy map.

206 We propose a temporal minimum redundancy - maximum relevance (TMRMR) feature selection

207 This apparent redundancy may ensure homeostasis if one neurotransmitte

208 Although enzymatic redundancy might be inferred from their close similarity

209 and optimization of motion, whether and how redundancy might promote motor learning has not been inv

210 This potential redundancy needs to be taken into consideration when int

211 ing off different design parameters, such as redundancy, node recovery time, and backup supply availa

212 Although source redundancy normally secures essential S1P signaling in d

213 estored to wild-type values, pointing to the redundancy of ABA sources and to the effectiveness of le

214 meostasis in the majority of contexts due to redundancy of adult function with E2F1 and E2F2.

215 Moreover, the redundancy of AGO3- and AGO4-bound sRNAs is much more th

216 repetitive proteins by exploiting the codon redundancy of amino acids and finding the least-repetiti

217 nsic drug resistance ensuing from functional redundancy of Bcl-2 proteins, but also abrogates extrins

218 Currently, the apparent redundancy of both toxins cannot be adequately addressed

219 related homolog bt1, indicating a functional redundancy of BT1 and BT2 for NUE.

220 proteins has been limited by the functional redundancy of conserved isotypes.

221 taken here overcomes a problematic molecular redundancy of CspC and CspE that likely explains why the

222 ir-58.1 single mutant, indicating functional redundancy of distinct members of this miRNA family.

223 coring potential compensatory role of tissue redundancy of DMD (or aggravating role of tissue paucity

224 mediated Robinow syndrome and the functional redundancy of DVL1, DVL2, and DVL3, we elected to pursue

225 e been developed independently, resulting in redundancy of efforts and lack of synergy.

226 on PRC2 activity and the partial functional redundancy of enhancer of zeste homolog 1 (Ezh1) and enh

227 m our laboratory suggested either functional redundancy of ERK isoforms or a predominant role for ERK

228 This work demonstrates a critical redundancy of EZH1 and EZH2 in maintaining hepatic homeo

229 s one of promising candidates because of the redundancy of Fe and N on the earth, its large magnetocr

230 ditional knockout mice, we show that genetic redundancy of Gata3 with paralog Gata2 in trophoblast pr

231 on anatomical pattern, also led to increased redundancy of GrC input combinations.

232 st protection from HSV-1 and demonstrate the redundancy of host protective mechanisms, especially fol

233 our results suggest functional divergence or redundancy of MCTP members in Arabidopsis and provide a

234 First, it takes advantage of high redundancy of miRNA reads and introduces joint mapping o

235 nce of PRC1 and illustrate the diversity and redundancy of PcG protein recruitment mechanisms.

236 The resulting redundancy of RITS may have eased the selection pressure

237 Redundancy of signaling pathways represented within GBMs

238 rmality, avoid burdening specialty services, redundancy of specialist attention, unnecessary travel),

239 ts of co-infections and in some instances by redundancy of symbiont benefits.

240 However, functional identity and functional redundancy of the community as a whole remain unchanged.

241 The redundancy of the genetic code implies that most amino a

242 This yields insights on the functional redundancy of the system as well as its behavioral versa

243 clinic have failed thus far, possibly due to redundancy of the target receptor.

244 tions concerning the possible specificity or redundancy of their functions.

245 e of any single ZDHHC, suggesting functional redundancy of these enzymes in the IFITM3-mediated antiv

246 As a result of the functional redundancy of these three cytokines on eosinophils and t

247 strong structural similarity and functional redundancy of these two enzymes, the mechanisms regulati

248 Redundancy of TOP1-mediated repair mechanisms is a major

249 here is a previously unrecognized functional redundancy of Trx f1 and NTRC in regulating photosynthet

250 Due to feature redundancy or outliers in samples, using all available d

251 The level of redundancy or specificity among these members is current

252 , but little is known about their functional redundancy, or if their mutation can be physiologically

253 am and 79 kb downstream) with median 27-fold redundancy per base.

254 The resulting genetic and functional redundancy prevents the analysis of their specific roles

255 Such redundancy reduces the probability of selection of favor

256 er, many variants of efficient coding (e.g., redundancy reduction, different formulations of predicti

257 ains of PATJ function, to a large extent, in redundancy, regulating the function of the protein.

258 target genes, however the advantages of such redundancies remain elusive.

259 isms, their biological roles and biochemical redundancies remain largely unclear.

260 spite their extreme diversity and functional redundancy, respond to disturbances like many macro-ecol

261 by including redundancy to combat noise, but redundancy sacrifices coding efficiency.

262 Regeneration employs effective redundancy schemes to compensate for the missing signals

263 data provide an explanation for the genetic redundancy seen in the CLV1 clade and reveal a novel fee

264 In this work, we quantify redundancy space and investigate its significance and ef

265 stingly, we also observed differences in the redundancy space between the dominant hand and nondomina

266 We propose that a larger redundancy space leads to faster learning across subject

267 tent with partially random binding patterns, redundancy, stochastic regulator binding, burst-like exp

268 This redundancy suggests that diseases, such as Hutchinson-Gi

269 ging in behavioral patterns characterized by redundancy (superfluous actions that exceed the function

270 ogether, these data emphasize the functional redundancy that leads to robustness in the cardiac proge

271 lutionary constraint, with enough functional redundancy that variation in, or even loss of, any parti

272 and an evolved system, demonstrating social redundancy to be the mechanism by which resilience to pe

273 sensory codes have to be robust by including redundancy to combat noise, but redundancy sacrifices co

274 ive of unappreciated evolutionary functional redundancy to facilitate angiogenesis and ensure mainten

275 ial transcription factor input, feedback and redundancy to generate cell type-specific levels of dve

276 We related this redundancy to hypothesized roles of temporal expansion o

277 n environments, from quadratic growth of the redundancy to oscillatory behavior.

278 ve elements that function cooperatively with redundancy to prevent spontaneous NF-kappaB activation.

279 t that several domains contribute, with some redundancy, to maintenance of the overall RRE shape.

280 rgitation, despite larger prolapse and valve redundancy, underscoring potential compensatory role of

281 ng subsets of tubulin genes whose functional redundancy varies between cell types and in vivo and in

282 Potential redundancy was addressed by co-deleting the closest para

283 Furthermore, despite the extensive redundancy, we show that mammalian MEF2 proteins regulat

284 This circuit is masked by feedback and redundancy when chemoattractant is used as the input, hi

285 utively expressed RAP2.3 contributes to this redundancy, whereas the hypoxia-induced HYPOXIA RESPONSI

286 stic value across different time steps, with redundancy, which is calculated by employing dynamical t

287 an fail to reveal function in the context of redundancy, which is frequently observed among duplicate

288 twork of signalling cascades with functional redundancy, which provides them with robust compensatory

289 ear load, providing mechanical isolation and redundancy while allowing spindle fluidity.

290 sistent with a widespread loss of functional redundancy, while adaptive radiations of gene families i

291 cifically, it is not known whether metabolic redundancy will foster competition or motivate cooperati

292 -methyltransferase with a partial functional redundancy with MLL3 (KMT2C).

293 H3K4me1/2 methyltransferase with functional redundancy with MLL3 (KMT2C).

294 029 grown under continuous light, suggesting redundancy with other ELF3 homologs or possibly an alter

295 n of LCMV-specific CD8(+) T cells because of redundancy with the costimulatory pathways induced by TN

296 c severity over males (MKOs), due to partial redundancy with UTY, a Y-chromosome demethylase-dead hom

297 sed to characterize functional diversity and redundancy within (alpha), between (beta) and across (ga

298 Our data reveal a high degree of redundancy within each protein family but also specializ

299 ence suggested that rather than a functional redundancy within the TIDA population, the dopamine/GABA

300 Due to genetic redundancy within this system, the carbohydrate specific