ライフサイエンスコーパス: redundant

1 esting that neuroligins are not functionally redundant.

2 k force concluded the term severe sepsis was redundant.

3 s that multiple FGLK motifs are functionally redundant.

4 neurons and are not completely functionally redundant.

5 which have been categorized as functionally redundant.

6 ereas NK and CD4(+) T cells were found to be redundant.

7 ptotagmin and otoferlin are not functionally redundant.

8 o homeostasis rather than being functionally redundant.

9 ber of features extracted might end up being redundant.

10 dPCR could discern individual copies of the redundant 23s rRNA gene in the enterococcal genome.

11 Furthermore, redundant abaxial-enriched ARF repressors suppress WOX1

12 We report that CheV1 and CheW have largely redundant abilities to interact with chemoreceptors and

13 Multiple redundant acoustic cues can contribute to the perception

14 Redundant activities of antagonistic Wnt signals, a temp

15 rm this new growth axis has been hampered by redundant activities of key transcription factors.

16 obe tract) neurons, worker pheromones induce redundant activity in both pathways.

17 e most severe RNA interference lines suggest redundant and additive GRCD activities in organ identity

18 lts here reported support the idea that both redundant and divergent functions of TAG1 and TAGL1 gene

19 t phosphoregulatory sites on alpha1C are not redundant and do not each fractionally contribute to the

20 s notions, matrix-remodeling systems are not redundant and give rise to precise ECM-cell crosstalk.

21 hown that EZH2 and EZH1 are not functionally redundant and inhibition of both EZH2 and EZH1 is necess

22 deficits in mice lacking NMB or GRP are non-redundant and Nmb/Grp double KO (DKO) mice displayed add

23 thin the superenhancer were not functionally redundant and that all were required for normal gene exp

24 hich predicts that defenses are functionally redundant and thus trade off, and the resource availabil

25 ic actins are hypothesized to carry out both redundant and unique essential functions, but studies us

26 ulators of vein formation may be genetically redundant and, thus, undetectable by forward genetic scr

27 he RXR and RAR isotypes are not functionally redundant, and it also unveils the combinatorial mechani

28 an entire population will make this activity redundant, and the HEN domain is expected to degenerate

29 rolonged duration, multiple antibiotics, and redundant antibiotic coverage), followed by a post-imple

30 In search of a redundant antiviral pathway, we identified a role for th

31 ved that ROCK1 and ROCK2 may be functionally redundant, as they share a highly conserved kinase domai

32 fy PE_PGRS47 as a functionally relevant, non-redundant bacterial factor in the modulation of innate a

33 ssion and complementation analyses suggest a redundant biochemical function between GNC and GNL, noth

34 ols exist for Uba1 and Uba6 that reflect non-redundant biological roles for Uba6.

35 are encoded by different genes that play non-redundant biological roles.

36 Therefore, we have uncovered redundant but differential contributions of MAP65-3 and

37 These phosphatases have redundant but essential roles in the release of seed dor

38 paralog MycN are thought to be functionally redundant, but Myc- and MycN-driven medulloblastomas exh

39 nesis and, as such, suggest that it is not a redundant bystander during coinfection with influenza A

40 ggest that postsynaptic Syt1 and Syt7 act as redundant Ca(2+)-sensors for Ca(2+)-dependent exocytosis

41 hy patients harbor a mutation in only 1 of 6 redundant CaM-encoding alleles, we devised a strategy us

42 In canvassing potentially redundant candidate genes, we identified developmentally

43 ts that different mce operons do not provide redundant capabilities and that M. smegmatis, in contras

44 omplex hydrocarbon mixtures requires the non-redundant capabilities of a complex oil-degrading commun

45 We report here that the redundant casein kinases Yck1p and Yck2p phosphorylate s

46 udy, we examine the hypothesis that multiple redundant cathepsins (not just cathepsin B) mediate this

47 y or ectopic expression of Wee1 (a partially redundant Cdk1 inhibitory kinase) and phenocopied by exp

48 ation (AmiC), as compared with three largely redundant cell separation amidases found in Escherichia

49 Multiple, non-redundant checkpoints are in place to prevent such poten

50 brush resides in a cluster of redundant CNGCs encoding subunits which resemble metazoa

51 l activity covaried trial by trial to form a redundant code.

52 on codes robust against corruption by noise: redundant codes can be very fragile, and synergistic cod

53 We use unique combinations of redundant codons to encode cPTMs with "silent barcodes"

54 nstrain combinatorial diversity by producing redundant combinations, which nevertheless could support

55 kpoint might be due to functional duality or redundant, competing mechanisms.

56 dundancy aids in motor learning and that the redundant component of motor variability is not noise.

57 ltiple similar spectrum signal summation and redundant/contaminant spectra removal, (iv) interpretati

58 us immune stress surveillance, including non-redundant contributions to protection from cutaneous car

59 BCL-2 and functionally redundant counterpart, MCL-1, are frequently over-expres

60 al NF-kappaB subunits p65 and c-Rel have non-redundant, critical roles in promoting Treg cell develop

61 and mass spectrometry, we identify 2,068 non-redundant cross-linked peptide pairs containing 245 intr

62 contact time with the DNA chain provides for redundant damage patrolling within individual DNA chains

63 in assignments (CATH-B); a new, strictly non-redundant data set of CATH domains suitable for homology

64 ely 2000 widely used plasmids to build a non-redundant database of plasmid features.

65 function to the TFBS prediction using a non-redundant dataset that consists of TFs from 12 different

66 These functions are redundant: defects at each channel can be rescued by fil

67 Our results support a non-redundant developmental role of NKX6-2 in humans and imp

68 We used Biosensor Imaging of Redundant Deviation in Shifts (BIRDS), which utilizes ch

69 ble for boosting expression because they are redundant, dispersed, and degenerate.

70 s been observed that many pairwise tests are redundant due to correlations in their genotype values a

71 , our data reveal how multiple and partially redundant EB1-binding sites provide a microtubule-associ

72 show that our method overcomes the need for redundant effort through the discovery and application o

73 and additional transcription factors through redundant elements dispersed throughout approximately 40

74 e the combined action of two independent but redundant endocytic recycling mechanisms, together with

75 at p63LRE is composed of additive and partly redundant enhancer modules that act to direct robust p63

76 also produced GrCs that were combinatorially redundant, even when input diversity was extremely high.

77 yeast Schizosaccharomyces pombe operate in a redundant fashion to control essential functions, includ

78 ptors have been shown to operate mostly in a redundant fashion, and very few specific roles have been

79 nt contribute to immune suppression in a non-redundant fashion, suggesting that both sources could be

80 However, with the presence of many redundant features, the most discriminative features are

81 ally, we find that non-orthogonal (partially redundant) filters with scaled additive noise tend to ou

82 Although STING is redundant for cell-autonomous antiviral resistance in as

83 mediated defence, with the fifth (PLD) being redundant for defence against some of the phages.

84 We discovered, however, that they are not redundant for formation of the higher order chemorecepto

85 These findings demonstrate that LRBA is redundant for host longevity while being essential for b

86 ged lymphoma survival and morphology but are redundant for lymphoma dissemination, suggesting that ta

87 movement in confined spaces, but is largely redundant for motility and chemotaxis in loose matrices.

88 , Tbx21 and Mcl1 that NCR(+) ILC3 cells were redundant for the control of mouse colonic infection wit

89 h, phenocopying myosins, whereas MadA1-4 are redundant for this process.

90 x, in agreement with previous work on highly redundant frames.

91 t), of which 16885 are unique molecules (non-redundant) from 377 manually curated studies of 230 publ

92 Consistent with their redundant function as activating kinases of Wts/Lats, co

93 These paralogous receptors share redundant function during development but play unique ro

94 tabolism or mediated by genes with partially redundant function.

95 substrates Cdc15 and Cyk3, confirming a non-redundant functional connection through shared substrate

96 nine in GRgamma is driven by a distinct, non-redundant functional profile, including regulation of mi

97 data provide the first demonstration of non-redundant functional roles for the regulatory TRAIL rece

98 emains to be understood why its premier, non-redundant functions are restricted to prolactin-induced

99 By contrast, CD81 and SR-BI fulfil redundant functions during infection by the rodent paras

100 We show conserved and redundant functions for several GRCD genes in regulation

101 onstrained genes that fulfill essential, non-redundant functions in host survival and reveals others

102 Arabidopsis SWR1c components could have non-redundant functions in plant immunity and gene regulatio

103 In summary, HNF4alpha isoforms perform non-redundant functions in the colon under conditions of str

104 that OsbHLH068 and AtbHLH112 share partially redundant functions in the regulation of abiotic stress

105 genes OsbHLH068 and AtbHLH112 have partially redundant functions in the regulation of the salt stress

106 nalysis suggested that many have overlapping/redundant functions in virulence.

107 ity to use a wide range of host factors with redundant functions in vRC assembly and function provide

108 rotein families often perform overlapping or redundant functions meaning that different variations wi

109 udy are to determine whether compensatory or redundant functions of ADAM17 in Notch signaling can exp

110 len-specific transmission defect, suggesting redundant functions of EXO70C1 and EXO70C2.

111 he human phenotypes, possibly because of the redundant functions of OCRL and its paralog type 2 inosi

112 mediating its actions and the unique versus redundant functions, have not been fully defined.

113 tory conditions into effector cells with non-redundant functions, such as dendritic cells and macroph

114 lar amounts in most tissues and have largely redundant functions.

115 ome duplication fosters genetic novelty, but redundant gene copies would undergo mutational decay unl

116 CRISPR-Cas9 is a useful approach to uncover redundant genes and to explore complex gene networks.

117 genes), DACE produced 9.8M clusters with 52K redundant genes in 1.5 hours of running time.

118 smoking-attributable cancer from the 48 non-redundant genes in the 11 oncogenic pathways.

119 ered a unique biotin scavenging pathway with redundant genes present in the probiotic bacterium L. la

120 from 287 pigs, we identified 7.7 million non-redundant genes representing 719 metagenomic species.

121 Bacillus subtilis seems to have redundant genes, bioI and bioW, for generation of the pi

122 functions for GRCD1 and GRCD2, two partially redundant genes, GRCD4 and GRCD5, were found to be indis

123 ped to select highly discriminative and less redundant genes.

124 bound state that allows AGO4 recruitment via redundant glycine-tryptophan/tryptophan-glycine AGO hook

125 GC response elements (GRE), suggesting a non-redundant GRIP1 function as a GR coactivator.

126 Thus, in organisms that do not express redundant H1 isoforms, the structural and biological fun

127 y potassium transporter and the functionally redundant Hal4 (Sat4) and Hal5 protein kinases.

128 ADR1 family - ADR1, ADR1-L1 and ADR1-L2 - as redundant helper NLRs, whose function is required for de

129 transcription factor Msn2 and its seemingly redundant homolog Msn4.

130 le kinase CDK6 has long been thought of as a redundant homolog of CDK4.

131 tion to benefit the bacteria, resulting in a redundant impact on virulence.

132 ta indicate that both LCs and Th17 cells are redundant in contributing to alveolar bone destruction i

133 gesting that most sunflower defenses are not redundant in function and that wild Helianthus represent

134 to the severity of chronic asthma, they were redundant in maintaining airway hyperreactivity and remo

135 Top1 and RNase H1 are partially functionally redundant in mammalian cells to suppress RNAP I transcri

136 ed whether Hdac1 and Hdac2 were functionally redundant in mature mouse brain.

137 a show that PDHK1 activity is unique and non-redundant in the family of PHDK enzymes and a PDHK1 spec

138 otentially render sentinel lymph node biopsy redundant in the future.

139 Here we show that RhoA is redundant in the melanocyte lineage but that Cdc42 coord

140 three isoforms of Pim protein appear largely redundant in their oncogenic functions.

141 Rab-GGT activity, and they are biochemically redundant in vitro.

142 UPS-indel identifies 15% redundant indels in dbSNP, 29% in COSMIC coding, and 13%

143 t UPS-indel is able to identify 456,352 more redundant indels in dbSNP; 2,118 more in COSMIC coding,

144 omplementary to gene features, providing non-redundant information and enhanced predictive power when

145 appear to provide complementary rather than redundant information.

146 easure zero, the environment always acquires redundant information.

147 utations can perturb or bypass the action of redundant inhibitory REs to achieve the level of hyperac

148 ons; that they combine multiple separate and redundant inputs, which are themselves interconnected in

149 A significant redundant interaction between IL1B +3954 C/T and FCGR2A

150 These findings reveal that redundant interactions at the replication fork must stab

151 ct through a subclavian vein puncture with a redundant loop in the atrium.

152 n is not essential, due to the presence of a redundant malonyl-CoA generating system provided by a cy

153 ntial for releasing E2A and E2-2, which in a redundant manner are required for antigen-induced B cell

154 bsence of Lig4, Lig1, and Lig3 function in a redundant manner in resolving switch region DSBs during

155 ts homologs RVE4 and RVE6 act in a partially redundant manner to promote clock pace.

156 remodeling factor, which acts in a partially redundant manner with Fcho proteins during the earliest

157 hat the GLFG repeats of Nup116 function in a redundant manner with Nup188, a nonessential scaffold Nu

158 they function in a parallel and potentially redundant manner.

159 late auxin levels in Arabidopsis in a highly redundant manner.

160 e onset of flower development in a partially redundant manner.

161 expression profiles of multiple and possibly redundant matrix-remodeling proteases (e.g., collagenase

162 ent, such networks commonly contain multiple redundant mechanisms designed to counteract loss or pert

163 ment was alleviated through the emergence of redundant mechanisms in B. subtilis and related organism

164 R-inclusion MCS, suggesting the existence of redundant mechanisms in MCS formation.

165 tment to uninfected salivary glands but that redundant mechanisms mediate T cell recruitment after MC

166 sults show that, in striking contrast to the redundant mechanisms sensitizing other modalities after

167 rationally directed to the complex and often redundant mechanisms underlying this interaction.

168 brate immune system uses multiple, sometimes redundant, mechanisms to contain pathogenic microorganis

169 ANXUR1 (ANX1) and ANX2, two redundant members of the CrRLK1L subfamily, are required

170 The redundant molecular mechanism that forms the elt-2 regul

171 Kif15 and Eg5 are partially redundant motors, and overexpressed Kif15 can drive spin

172 The results showed that AAP2(144-184) has redundant multipartite NLSs and that any combinations of

173 hat lost their target in the amputation into redundant muscles in the region of the stump.

174 ction are characterized by focally thick and redundant myelin.

175 ncreased degradation for a total of five non-redundant myofibrillar and sarcoplasmic proteins.

176 The potential benefits of these redundant network structures are not clear.

177 le at the population level, particularly for redundant neural codes.

178 -passing algorithm operating at the level of redundant neural populations.

179 he assembly graph contains massive amount of redundant nodes and branching edges.

180 works by simultaneously subtracting up to 19 redundant non-germ-line residues in the CDRs.

181 expression data from 49395 molecule entries (redundant), of which 16885 are unique molecules (non-red

182 anding debate as to whether the isoforms are redundant or perform specialized roles as part of a tubu

183 of a surprisingly complex array of seemingly redundant, parallel-acting cis-regulatory modules that d

184 hysically interacted with CLF, its partially redundant paralog SWINGER (SWN), and LHP1.

185 c tools to silence simultaneously a range of redundant pathways and main effectors of tumorigenesis i

186 l roles in crosstalk between alternative and redundant pathways and regulatory outcome of phosphoryla

187 ist et al. demonstrate that two separate but redundant pathways exist to recruit ESCRT-III proteins t

188 ce these genes and proteins, indicating that redundant pathways exist to respond to hepatocyte death.

189 d that Exo1 and Rqh1 function in alternative redundant pathways for promoting survival following repl

190 s have evolved a series of complementary and redundant pathways to limit pathologic immune responses

191 (CGR) 2 or 3 genes encoding two functionally redundant pectin methyltransferases.

192 ic sequences were prevented by comparison of redundant peptide pairs.

193 A total of 940 non-redundant peptides in the gastric compartment and 989 no

194 tides in the gastric compartment and 989 non-redundant peptides in the intestinal compartment were qu

195 dual free chlorine, combined with removal of redundant plumbing, was instituted.

196 c achieves this by upregulating a cluster of redundant pro-apoptotic BH3-only proteins and suppressin

197 This redundant processing of non-useful peaks is a bottleneck

198 -evoked avoidance is driven by parallel, non-redundant processing of volatile and nonvolatile kairomo

199 tion, but in the absence of the functionally redundant protein, Pex25, it becomes essential and less

200 Using 6637 non-redundant protein-protein interfaces, we revealed peculi

201 idations on a comprehensive set of 2,100 non-redundant proteins bound with 3,075 small ion ligands.

202 A total of 1,313 non-redundant proteins of MAM were identified, among which 1

203 ResQ was tested on 635 non-redundant proteins with structure models generated by I-

204 NeBcon was tested on 98 non-redundant proteins, which improves the accuracy of the b

205 in P. tenuiflora roots containing 2,671 non-redundant proteins.

206 PSs in the viral RNA sequence may result in redundant PSs already present in the genome fulfilling t

207 the auxiliary Pex18p, one of two supposedly redundant PTS2 co-receptors.

208 PCR amplification introduces redundant reads in the sequence data and estimating the

209 L antigen (and potentially RBC clearance) by redundant recipient pathways involving both FcgammaRs an

210 ion to produce a standard set of stable, non-redundant reference sequences.

211 phenotype (eggshell morphology), we observed redundant regulation, hence rejecting "simple regulation

212 As non-redundant regulators of intracellular cAMP gradients, ph

213 These results identify Pak1 and Pak2 as redundant regulators of myoblast differentiation in vitr

214 We developed a novel redundant-relevant learning paradigm to examine the conj

215 embers have unique roles or are functionally redundant remains poorly understood.

216 ver, the underlying transition trees prevent redundant replacements and permit the detection of the m

217 e accurate replication, numerous complex and redundant replication and repair mechanisms function in

218 CompMap enables the generation of a non-redundant representative sequence for the input sequence

219 Rhea is a comprehensive and non-redundant resource of expert-curated biochemical reactio

220 annotate observed k-turn motifs within a non-redundant RNA dataset based on sequence signatures and g

221 ot IL-1Rs in fibroblasts, whereas it plays a redundant role downstream from both TLRs and IL-1Rs in l

222 Taken together, these findings support a redundant role for adaptive Th17 cell- and innate gammad

223 These results reveal an essential and non-redundant role for CHC22 in neural crest development and

224 s reveal an indispensable role for ROCK, yet redundant role for isoforms 1 and 2, in cell cycle progr

225 surface dependences for Nap1 and Chz1 and a redundant role for these chaperones in H2A.Z deposition.

226 Here we establish that DOCK5 has a non-redundant role in regulating motile and invasive capacit

227 inase activity, play an additional, mutually redundant role in specifying the cardiac mesoderm (CM) a

228 alian evolution, suggesting an important non-redundant role.

229 cells where it is thought to play a largely redundant role.

230 rovides a mechanistic basis for both the non-redundant roles and the diverse mutant disease states of

231 ctively these results highlight multiple non-redundant roles for IRF8 dependent DCs in the maintenanc

232 Here we define non-redundant roles for TET1 at an early postimplantation st

233 e-8-deficientPstpip2(cmo)mice, demonstrating redundant roles for the NLRP3 inflammasome and caspase 8

234 d organization of the TAF12 variants and non-redundant roles for the two TAF12 variants in the unicel

235 loser to the cleavage site have critical but redundant roles in both assembly and self-cleavage.

236 While SOS-induced DNA polymerases play redundant roles in bypassing most of the O(4)-alkyldT le

237 -WASP-interactors WIP and WICH/WIRE play non-redundant roles in cancer cell invasion.

238 notype, suggesting their overlapping but non-redundant roles in copper delivery to Cox2.

239 he E3 ubiquitin ligases PARKIN and MUL1 play redundant roles in elimination of paternal mitochondria.

240 lirin and its paralog Trio play critical and redundant roles in excitatory synapse structure and func

241 rocytes and perform essential, but partially redundant roles in growth plate maturation.

242 tive apparatus of angiosperms with partially redundant roles in pollen development and pollination.

243 nsities for each diffusive state reveals non-redundant roles in the activation states of RhoA and Rho

244 uent domains, but they fill surprisingly non-redundant roles in the cell, with deficiencies in indivi

245 of DCs and have helped to identify their non-redundant roles in the immune system.

246 NDs indicates that both genes play partially redundant roles in ureterovesical junction formation.

247 the related RhoA and RhoC play additive and redundant roles in various aspects of endothelial barrie

248 The redundant roles of H3S10ph and H3S28ph might enable rapi

249 ranscriptional coactivators with unique, non-redundant roles that bind a wide array of proteins, incl

250 ta suggest that RsgA and LepA play partially redundant roles to ensure efficient 30S assembly.

251 omplicated the unwinding of their unique non-redundant roles.

252 l roots and root hairs showing they have non-redundant roles.

253 oliferation, so the two proteins play partly redundant roles.

254 lls and found they have unique but partially redundant roles.

255 GATA4 and GATA6 play essential, but redundant, roles in pancreas formation in mice, and GATA

256 lasticity, allowing parallel transfer of non-redundant sensory information to downstream centers.

257 emonstrated that the nervous system combines redundant sensory signals according to their reliability

258 -99.6% of STRs characterized with >/=10x non-redundant sequence coverage.

259 nd reduction of sequence errors by using the redundant sequence information and haplotype-based error

260 The enormous number of redundant sequenced genomes has hindered efforts to anal

261 SARG was curated to remove redundant sequences and optimized to facilitate query se

262 Our comparative analysis involving a non-redundant set of 551 inter-subunit interfaces in viral c

263 es were collected and combined to make a non-redundant set of bacterial genomes.

264 tor, suggesting that EV-D68 can use multiple redundant sialylated receptors.

265 ptor Baboon is required in R8 to receive non-redundant signaling from the three Activin ligands, acti

266 individual pathways within this complex and redundant signaling network is dependent on cellular con

267 psed appearance with overlapping sutures and redundant skin folds and, occasionally, intracranial her

268 s residual telangiectasia, anetodermal skin, redundant skin, persistent superficial component, and th

269 In contrast, redundant solutions may explain positive feedback, perha

270 ll lines; i.e., when all lines have the same redundant space regardless of their initial load.

271 RF-1 and its paralog MYRF-2 are functionally redundant specifically in synaptic rewiring.

272 in photoreceptors is directed exclusively by redundant splicing enhancers located in the adjacent int

273 nsferase MET-2/SETDB1 also show functionally redundant sterility, increased germline apoptosis, DNA r

274 all proteins with disulfide bridges in a non-redundant subset of PDB form complex lassos, and classif

275 brios is a replete medium with metabolically redundant substrates.

276 hways and that CXCR3 variant function is not redundant, suggesting a mechanism for tissue specific bi

277 for the elimination of microbes, dead cells, redundant synapses, protein aggregates, and other partic

278 ions, days of therapy over patient days, and redundant therapy events.

279 n described, but whether their functions are redundant, tissue-specific or integrated in the cGAS-cGA

280 SSO1327 is non-redundant to IcsA; its activity is independent of type I

281 hibitory mechanism that is parallel, but not redundant, to MCC formation.

282 an open-access database storing curated, non-redundant transcription factor (TF) binding profiles rep

283 rted several specialized, complementary, and redundant transcriptional and immunomodulatory effects.

284 r Arabidopsis (AtRTD2) containing 82,190 non-redundant transcripts from 34 212 genes.

285 From all the non-redundant transcripts that were assembled, bioinformatic

286 From all the non-redundant transcripts that were assembled, bioinformatic

287 ehensive transcriptome comprising 95,516 non-redundant transcripts was assembled.

288 It consists of more than 10,000 non-redundant transport systems with more than 11 000 refere

289 y reduces PD-L1(+) cells and facilitates non-redundant tumour infiltration of effector CD8(+), CD4(+)

290 tivation is achieved in diverse, potentially redundant ways, the clinical efficacy of these inhibitor

291 age waveform, the BK channel is functionally redundant whereas hERG is essential.

292 in viral-specific CD8(+) T cells is slightly redundant with costimulatory signals.

293 These functions of hKif15 are partially redundant with Kinesin-5 (Eg5), which can cross-link and

294 hat PI3Kalpha and PI3Kbeta were functionally redundant with PI3Kdelta in Tconv.

295 dial sorting and myelination and that Yap is redundant with Taz.

296 alization was BMI1-independent and partially redundant with that of BMI1 for H2A(ub) deposition, cons

297 ni anemia proteins and that this activity is redundant with the 5'-3' exonuclease SNM1A.

298 reveal that C18 executes a role that is not redundant with those of B12/B14 during SV40 infection.

299 ctions of ILCs are specialized and which are redundant with those of T cells.

300 Rail-RNA eliminates redundant work across samples, making it more efficient