ライフサイエンスコーパス: refine

1 ngage in a dissociable manner as actions are refined.

2 es of the human genome that we completed and refined.

3 frontotemporal dementia (FTD) attempting to refine a neurocircuitry model and inform clinical defini

4 In this work, we refined a derivatization gas chromatography-mass spectro

5 The authors refined a model for exosporium assembly.

6 The described method refines a GPCR binding pocket conformation using a singl

7 tive phenomena theoretically tractable, help refine accounts of social perception, and illuminate som

8 Experts further refined, added, or removed metrics during structured tel

9 This prior was then refined against small-angle X-ray scattering (SAXS) data

10 ardiovascular system and its pathophysiology refined all aspects of care for these patients.

11 Here, we refine an earlier model in an outward (OWF) and develop

12 gma(N) The structure allowed us to build and refine an improved sigma(N)-holoenzyme model based on pr

13 We have refined an atomic model for each map and identified an e

14 ility, and affordability of DHA supplements, refining an omega-3 intervention in APOE4 carriers is wa

15 of ultra-high-field fMRI in generating more refined, anatomically informed, functional accounts of h

16 al work, which will in turn provide input to refine and develop the model.

17 ere is a lack of clinical trials required to refine and update standardized and evidence-based therap

18 We describe a refined and accessible method to non-subjectively, rapid

19 A similar difference was observed for other refined and cold-pressed vegetable oils.

20 More recently, a number of studies have both refined and expanded our understanding of LSCs and intra

21 We refined and extended this strategy, finding that incorpo

22 ugh the concept of the atopic march has been refined and strengthened by many cross-sectional and lon

23 is and related diagnostic criteria have been refined and updated by the consensus group and the World

24 We illustrate the refined approach for hydrogen production from methane-cr

25 ional subscale scoring algorithm and a Rasch-refined approach producing visual function and socioemot

26 A refined approach to generating interspecies chimeras cou

27 project's anemia analyses.The BRINDA project refines approaches to interpret iron and vitamin A bioma

28 Without developing and refining approaches to reach and vaccinate children and

29 y the expert panel (leveraging partnerships, refining assessment methodologies and enhancing communic

30 include 24 novel SLE regions (P<5 x 10(-8)), refined association signals in established regions, exte

31 Results were discussed and refined at a multistakeholder workshop held May 12, 2016

32 ial, coarse sensitivity to 3D information is refined, automatized and retained over the lifespan.

33 veloped an extensive benchmark comparing LDM-refined binding pockets to GPCR X-ray crystal structures

34 ust pair of (14)C and (40)Ar/(39)Ar ages for refining both the radiocarbon calibration curve and the

35 enerated an initial list of items, which was refined by a 2-round Delphi survey involving nearly 250

36 Face selectivity is refined by a decreasing responsiveness to non-face stimu

37 of transcriptional activity and subsequently refined by epigenetic silencing of transcripts associate

38 elements of the complex molecular mechanism refined by evolution to allow for a fine tuning of p38al

39 Matches are then refined by examining their varying elements.

40 on microbial composition, which was further refined by filtration and influenced by distribution and

41 s the elongated grains in ECAP-2 sample were refined by recrystallization, while equi-axed grains in

42 Histone wild-type subgroups are refined by the presence of key oncogenic events or methy

43 a novel method whereby raw lariat reads are refined by U2snRNP/pre-mRNA base-pairing models to retur

44 st, replacement of saturated fat with mostly refined carbohydrates and sugars is not associated with

45 ta suggest that in utero exposure to dietary refined carbohydrates may predispose offspring to an obe

46 la melanogaster, a widely-used technique for refined cell type-specific manipulation is the Split GAL

47 nutritional and health benefits of partially refined cereals and limitation of their main drawbacks.

48 ranging from water purification to petroleum refining, chemicals production, and carbon capture have

49 nical evaluation of genomic alterations have refined classification of myeloid neoplasms and major fo

50 of genetic testing, a detailed pedigree, and refined clinical surveillance recommendations for family

51 at allows analysts to evaluate, compare, and refine cluster assignments based on the source data, der

52 e, for which further studies are required to refine conclusions, the OMP's chemical structure was a d

53 consistent neural trajectories that generate refined control.

54 Experience and activity refine cortical circuits through synapse elimination, bu

55 nd discuss the experimental pH effects using refined coupled (PCET) and decoupled proton transfer-ele

56 emphasis on the updated WHO classification, refined criteria, additional prognostic parameters, and

57 hich motivation impacts behaviour, and helps refine current models of catecholaminergic modulation of

58 Understanding and refining current approaches to vaccinating populations i

59 To refine detection of PD-L1, we have identified a peptide,

60 ) (13 of 53 [25%] of patients with HNSCC) by refining diagnoses and matching patients to specific the

61 tissue-based analysis of gene transcripts to refine diagnosis of heart transplant rejection.

62 We highlight the need for refined diagnostic tools and effective control options t

63 lying white matter architecture is similarly refined during development, potentially allowing for imp

64 This subcellular map can be used to refine existing protein-protein interaction networks and

65 time-specific therapeutic strategies and to refine existing treatments.

66 nd sensorimotor circuits that challenges and refines existing views of corticostriatal function and e

67 ng methods to reduce the number of subjects, refine experimental designs, and replace live animals.

68 ms, this modelling approach could be used to refine experimental targets for potential T-cell vaccine

69 This refined expression profiling technique distinguished gen

70 of hydrogen; Barkas scaling formula has been refined, extending its applicability down to about 10 ke

71 testing can improve diagnostic accuracy and refine family management.

72 ides and bioactive components as compared to refined flour fraction.

73 and arabinoxylans (up to R=0.80) in bran and refined flour fractions.

74 d, and pericarp-enriched (PE) wheat bran and refined flour was investigated using time-domain proton

75 bran of high altitude cultivars affected the refined flour yield inversely.

76 , lutein resulted mainly concentrated in the refined flour.

77 a higher total antioxidant activity than the refined flour.

78 e anthocyanin and total phenolic contents of refined flours ranged between 3.9-7.6mug/g and 1299-1607

79 illing resulted useful for the production of refined flours rich in xanthophylls, with particular emp

80 systems biology, genetic engineering and bio-refining for optimizing algae strains.

81 ethods to examine the visual field have been refined from early kinetic perimetry to current standard

82 The modulated structure was refined from the single-crystal X-ray diffraction data w

83 s crucially needed to reduce uncertainty and refine future estimates.

84 timates the relevance of individual factors, refines gene set annotations, and infers factors without

85 es by Whitaker et al. and Lim et al. provide refined genetic tools for dissecting the spatial organiz

86 monstrating the utility of this approach for refining genetic association signals.

87 analysis and may provide the basis for more refined graduation strategies of cartilage degeneration.

88 gned to consume a whole grain-rich (WG) or a refined grain-based (RG) diet for 6 wk.

89 le grain-rich diet group (WG) but not in the refined grain-based diet group (RG) (P-diet-by-time inte

90 hole grains plus 40 +/- 5 g dietary fiber/d; refined grain-based diet: 0 g whole grains plus 21 +/- 3

91 No associations were observed between refined-grain intake and infant growth.Higher maternal r

92 ta are lacking.We prospectively investigated refined-grain intake during pregnancy in association wit

93 demographic, lifestyle, and dietary factors.Refined-grain intake during pregnancy was positively ass

94 ain intake and infant growth.Higher maternal refined-grain intake during pregnancy was significantly

95 e effects of diets rich in WGs compared with refined grains (RGs) on immune and inflammatory response

96 Refined grains, a major source of dietary carbohydrates,

97 stern diets (rich in red and processed meat, refined grains, and desserts) with colorectal cancer ris

98 dings for fast foods, carbonated drinks, and refined grains, and high negative loadings for whole fru

99 Western (high in red meat, refined grains, and high-fat dairy) and prudent (high in

100 the effects of substituting whole grains for refined grains, independent of body weight changes, on e

101 thy plant foods (juices/sweetened beverages, refined grains, potatoes/fries, sweets) and animal foods

102 ake of sugar-sweetened and diet soft drinks, refined grains, red and processed meat, and margarine, a

103 2 major food groups, including whole grains, refined grains, vegetables, fruits, nuts, legumes, eggs,

104 The substitution of 1 serving refined grains/d with an equal serving of whole grains d

105 pression profiles for hundreds of tumors, we refined HNSCC subtypes by their malignant and stromal co

106 Future measurements will refine how R d aggregates to whole-plant respiration.

107 al health state, and, such patterns may help refine hypotheses about modes of pathogenesis.

108 ication and regression tree model to further refine identification of ICU stays using administrative

109 emonstrated acceptable accuracy and provided refined IgE characterization in 47% of the patients comp

110 the local problem; monitoring; testing; and refining improvements, analysis of data, and interpretat

111 The displacement model was refined in a supercell as well as in an equivalent comme

112 This basic understanding is refined in the course of development.

113 and AOX1D wild-type protein activity using a refined in vitro system.

114 Metabolic control may be relevant for refining inclusion criteria of clinical trials in the se

115 me these limitations and have led to new and refined insights into recombination mechanisms, includin

116 estimates of mass eruption rate and help to refine interpretations of eruption dynamics.

117 renewable natural bioactives possible to be refined into chemically standardized mixtures for biolog

118 This refined knowledge is essential to better guide translati

119 s associated with the text-derived labels to refine label-prediction confidence.

120 ary climate cycles across continents suggest refined lessons for managing genetic diversity in today'

121 for inferring disease transmission to a more refined level than previously.

122 om in vitro sources, it will be necessary to refine markers of HSCs matured ex vivo.

123 ir cell spontaneous activity and may further refine maturation.

124 Refined measurements of supraglacial DOM and their cycli

125 Using these refined methods, we efficiently and specifically targete

126 mouse model of cryptosporidiosis, but a more refined model for efficacy is needed.

127 a re-evaluation of published findings and a refined model of IQGAP scaffolding.

128 Altogether, this work provides a refined model of the PRORP-tRNA complex that illustrates

129 Based on our results, we propose a refined model of transcription initiation by the human m

130 ng DCM with causal manipulations to test and refine models of cognition.

131 was used to generate hundreds of alternative refined models for the CASP12 experiment, boosting our g

132 In all cases, the LDM-refined models had superior performance in enriching for

133 in providing output for multiple alternative refined models in a way that allows users to quickly vis

134 pare the specific regions of the alternative refined models in which they are most interested e.g. ke

135 connectivities need to be incorporated into refined models of plant cell wall structure, growth and

136 LDM-refined models showed improvement in VS performance over

137 ge and experimental insights can be used for refining models.

138 There is a need for a more refined, molecularly based classification model for glio

139 sidering the reverse mutation and by using a refined, more reliable data set, based on a new release

140 Characterizing HLA LOH with LOHHLA refines neoantigen prediction and may have implications

141 sparate circumstances: during development to refine neuronal connections, after injury to clear damag

142 Solar System, and provides a constraint for refining numerical solutions for insolation, which will

143 Internet and its most advanced applications refine obtained data for the user.

144 Operators should inspect and manually refine OCT retinal layer segmentation when assessing RNF

145 Then we analyzed partially and fully-refined oils from Italy, Tunisia and Spain.

146 f TPO against the primary oxidation of these refined oils was significantly correlated to their lycop

147 and anisidine value, PV and AV) required for refined oils.

148 The efficacy of TPO in stabilizing refined olive (ROO) and sunflower (RSO) oils was investi

149 revealed synergetic interactions for DF and refined olive oil-bound antioxidants, and antagonistic i

150 rive the topological transitions that either refine or deform a tissue.

151 notype data and fitness data to validate and refine our KPPR1 model.

152 rn tones; experience with food and wines can refine our pallet (and unfortunately more quickly empty

153 oped, it is equally important to continue to refine our understanding and interpretation of viral str

154 These results refine our understanding of drusen development, and prov

155 isms in specific lung cell types will better refine our understanding of respiratory disease pathogen

156 Studies with longer follow-up are needed to refine our understanding of the safety of shipping donor

157 to this forest ecosystem and contributes to refine our understanding of the sources and processes th

158 These findings refine our understanding of the spatially varying electr

159 Our results refine our understanding of UFM1-UBA5 binding.

160 ents, although more specific signatures have refined our prognostic abilities.

161 In response to the commentaries, we have refined our suggested model and discussed ways in which

162 Such approaches have already refined our understanding of the alloimmune response and

163 While refining our understanding of transplantation immunobiol

164 It is normally refined out of the opioids that the latex is typically c

165 ount of antioxidants can be preserved in the refined palm oil up to 99%.

166 foundation to discover new opportunities to refine personalized cancer therapies.

167 foundation for discovering opportunities to refine personalized cancer therapies.Significance: Syste

168 Biological materials (UVCBs), including many refined petroleum products, present a major challenge in

169 biome interactions, and (5) characterize and refine plant genotype-by-environment-by-microbiome-by-ma

170 ch couples EOM selection with an iteratively refining pool to give confidence in the underlying struc

171 We refined previously reported associations at 9p24.3 and 1

172 lignans can be used as marker of undeclared refining procedures in commercial extra-virgin and/or Vi

173 occur only during the bleaching step of the refining process and remain unaltered after the final de

174 erein we describe the influence of olive oil refining processes on the lignan profile.

175 Despite widespread use to characterize and refine prognosis, validation data of two-dimensional (2D

176 ging features to enhance diagnostic efforts, refine prognostic recommendations, and influence the ini

177 ccurate diagnosis, direction of therapy, and refined prognostication.

178 n of integrated processes and to a wealth of refined qualitative and quantitative data.

179 gical conditions can be used to develop more refined regional-scale EF5r estimates required for compi

180 cTAIR will be of general use in contextually refining regulator target genes for discoveries across m

181 europlasticity and suggest the potential for refining rehabilitation strategies for stroke patients.

182 (e.g. morphogens), but how these domains are refined remains unclear.

183 t on mercury emissions, helps to improve and refine reported emission inventories, and can serve for

184 rials planning meeting in 2012 to update and refine response criteria for patients with neuroblastoma

185 The extent to which an SNP panel can refine risk in women who receive preventive therapy has

186 for clinical trials that attempt to further refine risk prediction by incorporating genetic testing

187 , however, both LA volume and strain further refine risk stratification for new-onset AF.

188 o guide clinical decision making and further refine risk stratification.

189 tic subtype-specific MRD values allowed more refined risk group stratification.

190 n, RNA, and protein, providing insights into refining sarcoma therapy and relationships to other canc

191 IRT2 inhibitors and to the identification of refined, second generation inhibitors.

192 nt decisions and CO2 emissions policy in the refining sector.

193 of shell formation in C.gigas, supporting a refined shell formation model including chitin and ECM-r

194 Case study 2 uses this refined simulation method to test for a settlement gap i

195 This refined spatial perspective provides unique understandin

196 Our results also show that refining species distributions with DGVM outputs had lar

197 The latest fabrication routes based on refined starting powders and dopants, with innovative si

198 l of the identified transport system to help refine strategies that could improve patient survival ac

199 NAs undergo transfer between cells through a refined structural connection.

200 and rR studies have been used to establish a refined structure for the diferric cluster of CmlI(P).

201 t containing annotated phase information and refined structure models.

202 This refined structure provided a significantly improved fit

203 ing as an additional adjunct to help further refine subtypes of DCM, especially where arrhythmia risk

204 lia, the per capita availability of added or refined sugars and sweeteners was shown to have fallen 1

205 diacylglycerol(DAG)-rich oil from a blend of refined sunflower and rice bran oils.

206 urkey populations, with the ultimate goal of refining surveillance in these populations to enhance ea

207 d techniques provides the potential for more refined, targeted approaches to cardiovascular medicine.

208 To permit more refined targeting, we introduce here the "Killer Zipper"

209 on from no volitional muscle activation to a refined, task-specific activation pattern and movement g

210 with high accuracy, whereas the use of more refined techniques from artificial intelligence enabled

211 In this article, we refine the analytical uncertainty analysis by a more pre

212 we collected a global sample of XFS cases to refine the association at LOXL1, which previously showed

213 More broadly, these results refine the central hypothesis that dopamine-system defic

214 This novel methodology may refine the characterization of infectious and inflammato

215 These results suggest that the striatum may refine the code for time by integrating information from

216 Research to further refine the criteria should focus on optic nerve involvem

217 Our findings refine the current interpretation of the continuum band

218 , a boundary-clustering algorithm is used to refine the DCD-linker locations.

219 The aims of the current statement are to refine the definition of quality in cardiovascular imagi

220 e aims of this systematic review are to: (1) refine the definition, (2) characterize the incidence, a

221 ovides facilities for users to interactively refine the domain models by adjusting DC-score threshold

222 To refine the existing clinically based recursive partition

223 To refine the existing RPA, significant protein biomarkers

224 otype [panel of biomarkers]) with the aim to refine the management of this condition.

225 Here, we extend and refine the MitoB method to make it suitable for ecologic

226 penalized regression was applied to further refine the model and choose the final sparse SNPs.

227 and demonstrate icTAIR's power, we use it to refine the MSigDB c3 database of TF, miRNA and unclassif

228 atigraphy and mammalian biostratigraphy that refine the onset of basin fill to approximately 25.5 Myr

229 ollected on the feed frame table was used to refine the PLS model.

230 hods usually either used the GO hierarchy to refine the prediction results of multiple classifiers, o

231 t can be directly queried to interrogate and refine the regulatory framework defining IBD.

232 Leveraging Hippocampome.org, we validate and refine the relationship between axonal-dendritic colocat

233 The results also help to refine the role of the newly discovered third divalent m

234 To further refine the rules governing binding to the AR of zDHHC17,

235 en the ASR trimer subunits that were used to refine the ssNMR structure of ASR.

236 and solid-state NMR (ssNMR) spectroscopy to refine the structure of an oligomeric integral membrane

237 yophytes, lycophytes, ferns, and angiosperms refine the time-of-origin for conserved miRNA families a

238 based approach to MN, used to complement and refine the traditional proteinuria-driven approach, will

239 useful to identify potential biomarkers, to refine the understanding of the molecular mechanisms of

240 ts could prove useful in breeding efforts to refine the vernalization requirement of temperate cereal

241 minimize loops, (ii) docking methodology to refine the VL-VH relative orientation and (iii) de novo

242 Here, we refined the association signal, performed conditional an

243 We refined the CC composition and explored PEG and islet-li

244 We refined the features to predictive models (support vecto

245 We further refined the specificity of the proteins identified by co

246 Here, we have refined the technique and incorporated it into a streaml

247 This refines the current paradigm that canopy assimilation an

248 h a simple grain-refinement treatment, which refines the grain size to 4 mum.

249 troduce an algorithm, xHLA, that iteratively refines the mapping results at the amino acid level to a

250 dgehog protein levels, while later expansion refines the pattern.

251 Suggestions for refining the ACA and its market-based insurance system a

252 nal genome assays opens new perspectives for refining the classification of tumors with genetic insta

253 on and therefore provide novel insights into refining the current understanding of functional require

254 It also provides a new framework for refining the exploration of these unique environments.

255 nd functional maturation of the neocortex by refining the final number of cortical neurons in a regio

256 th agenesis, many gaps in knowledge exist in refining the genotype-phenotype correlation between PAX9

257 ins in representative dinucleotide steps and refining the models against SAXS data, a broad array of

258 esent improvements in the OMA algorithm: (i) refining the pairwise orthology inference step to accoun

259 Further research in refining the predictive value of these models is needed

260 D ssRNA models into ssDNA 3D structures, and refining the resulting ssDNA 3D structures.

261 trans-membrane helices, making mutations and refining the structure with different amounts of flexibi

262 Ns become available, it will be necessary to refine their activity before they can be translated into

263 rience of 20 laboratories worldwide that are refining their image-based cell-profiling methodologies

264 e can gain important insights that will help refine theory.

265 nvestigate disease mechanisms or develop and refine therapeutic strategies.

266 and trial concepts that will lead to a more refined therapy for this tumour type.

267 , this approach makes it possible to further refine these long read regions with the initial insuffic

268 patocytes in vitro and in vivo In efforts to refine these models, we constructed knock-in mice in whi

269 Further studies are needed to confirm and refine these recommendations.

270 We refine this requirement temporally to the early pupal st

271 rectional modulation of PFC activity further refined this subset of brain regions and identified the

272 robust place field activity, then plasticity refines this representation into one with less strongly

273 causation, an effective system is needed for refining this catalogue of differentially abundant micro

274 few months after birth, but is subsequently refined through development.

275 xcitatory maps is that maps are sculpted and refined throughout development and/or through sensory ex

276 its X-ray crystal structure in the apo-form (refined to 1.35 A), bound to NAD(+) (1.45 A), and bound

277 r their lexical variants, which were further refined to 25 520 abstracts, 43 253 sentences and 3984 c

278 The MCDR3 locus is thus refined to a shared region of 39 kb that contains DNAse

279 Multiple models have been developed and refined to estimate the overall activation energy and it

280 tial for feasible application in natural gas refining to gasoline and materials under moderate operat

281 e and tissue type, providing clinicians more refined tools to evaluate prognosis and treatment.

282 low-frequency (0.01 Hz) calcium oscillations refine topographic maps.

283 EnCs) propagated using a dual media approach refined towards regulatory compliance showed expression

284 lpipe emissions and emissions from petroleum refining, transport, and storage, but increases electric

285 ecular risk stratification should be used to refine treatment regimens for children with ependymoma t

286 The goal of the workshop was to explore and refine understanding about the existing knowledge gaps a

287 This refined understanding can facilitate better projections

288 This refined understanding can help improve interpretation of

289 Previous work has resulted in a refined understanding, commonly termed the molecular clu

290 Then, the results are refined using our recent advanced model for elastoplasti

291 Crystal structure was refined using Rietveld method and lattice parameters are

292 ategy gives chemists the tools to design and refine vast libraries, stress "druglikeness", and rapidl

293 of the AR and GR DNA-binding domains using a refined version of SELEX-seq.

294 ield's environment impact, it is critical to refine what can be made to what should be made.

295 grain wheat (57-449microg/g DM) compared to refined wheat (11-92microg/g DM) breads.

296 be predicted using a general model built on refined wheat (adjusted R2: 0.9986).

297 Refined wheat flour and hulless barley bran (from 9 diff

298 or patients with alopecia areata and further refine which subtypes of the disease these methods are b

299 Tellurium, a byproduct of copper refining, which is critical to solar photovoltaics, is c

300 renatally; indications for surgery have been refined with evidence, and minimally invasive pyeloplast