ライフサイエンスコーパス: refined

1 he enhancer locations are significantly more refined.

2 es of the human genome that we completed and refined.

3 ndications for surgical management have been refined.

4 colorectal cancer and obesity continue to be refined.

5 e at which venom peptides are discovered and refined.

6 93 participants as the list of outcomes was refined.

7 ngage in a dissociable manner as actions are refined.

8 In this work, we refined a derivatization gas chromatography-mass spectro

9 Here, we refined a high-yield subunit HCV vaccine that elicited b

10 The authors refined a model for exosporium assembly.

11 We have previously developed and refined a nonhuman primate (NHP) large animal GVHD model

12 measurement of exposures and diseases enable refined accuracy of data collection.

13 ion of natural communication stimuli that is refined across successive processing stages thereby lead

14 atural communication stimuli that is further refined across successive stages of processing in the we

15 Experts further refined, added, or removed metrics during structured tel

16 A refined Aer PAS-HAMP interaction model is presented.

17 This prior was then refined against small-angle X-ray scattering (SAXS) data

18 Best-ranked glob models can be further refined against solvent accessibility data, if available

19 provides a global picture of motions and was refined against the diffuse data, whereas the TLS and NM

20 ardiovascular system and its pathophysiology refined all aspects of care for these patients.

21 We have refined an atomic model for each map and identified an e

22 of ultra-high-field fMRI in generating more refined, anatomically informed, functional accounts of h

23 We describe a refined and accessible method to non-subjectively, rapid

24 A similar difference was observed for other refined and cold-pressed vegetable oils.

25 More recently, a number of studies have both refined and expanded our understanding of LSCs and intra

26 We refined and extended this strategy, finding that incorpo

27 put at the workshop, guidelines were further refined and finalized.

28 r engagement, the research team successfully refined and implemented a patient-centered study protoco

29 planning, and device implantation have been refined and optimized such that clinical outcomes are ge

30 ugh the concept of the atopic march has been refined and strengthened by many cross-sectional and lon

31 is and related diagnostic criteria have been refined and updated by the consensus group and the World

32 whether T and N categories should be further refined and whether non-anatomical factors might augment

33 Suggestions were collated, refined, and prioritized during the latter half of the s

34 ood conservation, etc), and postoperatively (refined anticoagulation, improved wound dressings, etc).

35 We illustrate the refined approach for hydrogen production from methane-cr

36 ional subscale scoring algorithm and a Rasch-refined approach producing visual function and socioemot

37 A refined approach to generating interspecies chimeras cou

38 immunoprecipitation sequencing (ChIP-Seq) we refined AR-binding and AREs at a genome-scale in androge

39 ation of energy balance is continually being refined as new details emerge.

40 include 24 novel SLE regions (P<5 x 10(-8)), refined association signals in established regions, exte

41 Results were discussed and refined at a multistakeholder workshop held May 12, 2016

42 n RELION to obtain a density map and a fully refined atomic model of MamK in filamentous form at 3.6-

43 mprovements in electron density maps and the refined atomic model.

44 ial, coarse sensitivity to 3D information is refined, automatized and retained over the lifespan.

45 veloped an extensive benchmark comparing LDM-refined binding pockets to GPCR X-ray crystal structures

46 (3-MCPD) esters and glycidyl esters (GEs) of refined, bleached and deodorized (RBD) palm olein during

47 s within a single region reveal the value of refined brain maps to appreciate the genetic complexity

48 enerated an initial list of items, which was refined by a 2-round Delphi survey involving nearly 250

49 Face selectivity is refined by a decreasing responsiveness to non-face stimu

50 doxin) on cytochrome P450cam conformation is refined by attaching two different spin labels, MTSL or

51 MelB- and LacY-based crystal structures and refined by biochemical analysis.

52 of transcriptional activity and subsequently refined by epigenetic silencing of transcripts associate

53 elements of the complex molecular mechanism refined by evolution to allow for a fine tuning of p38al

54 Matches are then refined by examining their varying elements.

55 on microbial composition, which was further refined by filtration and influenced by distribution and

56 connected under anesthesia and were further refined by iterative optimization.

57 generates initial guesses, which are further refined by least squares fitting.

58 Tilapia proteins refined by pH shift and water washing were chopped under

59 ttributes of sensory stimuli is continuously refined by practice, even throughout adulthood - a pheno

60 s the elongated grains in ECAP-2 sample were refined by recrystallization, while equi-axed grains in

61 ally broad patterns of transcription but are refined by repression in the mesoderm following mitosis.

62 Transition outcomes were refined by the 3 waves of the Delphi process, with quali

63 citatory cortical and subcortical inputs are refined by the fourth week of development, whereas local

64 cortex, and found that excitatory inputs are refined by the fourth week of development, whereas local

65 Histone wild-type subgroups are refined by the presence of key oncogenic events or methy

66 ing of these motor structures can be further refined by the use of electrophysiological approaches.

67 a novel method whereby raw lariat reads are refined by U2snRNP/pre-mRNA base-pairing models to retur

68 Refined cancer models are needed to bridge the gaps betw

69 s may necessitate the identification of more refined, cancer-specific signaling nodes.

70 st, replacement of saturated fat with mostly refined carbohydrates and sugars is not associated with

71 ta suggest that in utero exposure to dietary refined carbohydrates may predispose offspring to an obe

72 nding that the CPS+EG score facilitates more refined categorization into prognostic subgroups than cl

73 A refined cell isolation protocol and an improved flow cyt

74 la melanogaster, a widely-used technique for refined cell type-specific manipulation is the Split GAL

75 nutritional and health benefits of partially refined cereals and limitation of their main drawbacks.

76 ghly crystalline islands of MoS2 grown via a refined chemical vapor deposition synthesis technique.

77 a second life as a drug target, with either refined classic GCs or a novel generation of nonsteroida

78 nical evaluation of genomic alterations have refined classification of myeloid neoplasms and major fo

79 tanding of transplantation immunobiology has refined clinical management and improved outcomes.

80 of genetic testing, a detailed pedigree, and refined clinical surveillance recommendations for family

81 We then demonstrate refined clonal trackability of melanoma cells using this

82 These studies highlight the value of the refined colchicine-site model and identify a new pyrrole

83 al and epigenetic regulation is facilitating refined control over cell function and decision making.

84 consistent neural trajectories that generate refined control.

85 nd discuss the experimental pH effects using refined coupled (PCET) and decoupled proton transfer-ele

86 The Seattle and refined criteria reduced the cost to $92 and $87 per ath

87 The Seattle and refined criteria reduced the number of positive ECGs to

88 mpact on cost after applying the Seattle and refined criteria was evaluated retrospectively.

89 emphasis on the updated WHO classification, refined criteria, additional prognostic parameters, and

90 We here utilize refined data from transcriptomes (370 loci) to stabilize

91 eb services, programmatic data access, and a refined data model for handling gene network data in add

92 re precise understanding of physiology, more refined diagnoses, better disease risk assessment, earli

93 idity scores (p < 0.001), higher all-patient refined diagnosis-related group mortality risk (p < 0.00

94 We highlight the need for refined diagnostic tools and effective control options t

95 Longer length of stay and higher All Patient Refined Diagnostic-Related Groups severity of illness we

96 emotional actions, a fundamental adult skill refined during adolescence.

97 lying white matter architecture is similarly refined during development, potentially allowing for imp

98 peculiar adaptations, haidomyrmecines had a refined ecology shortly following the advent of ants.

99 The results also lead to a refined ERBB2 amplicon of 106 kb and show that several c

100 This refined expression profiling technique distinguished gen

101 of hydrogen; Barkas scaling formula has been refined, extending its applicability down to about 10 ke

102 ides and bioactive components as compared to refined flour fraction.

103 and arabinoxylans (up to R=0.80) in bran and refined flour fractions.

104 olic acids from wheat bran, whole-wheat, and refined flour samples was investigated using two extract

105 d, and pericarp-enriched (PE) wheat bran and refined flour was investigated using time-domain proton

106 bran of high altitude cultivars affected the refined flour yield inversely.

107 a higher total antioxidant activity than the refined flour.

108 , lutein resulted mainly concentrated in the refined flour.

109 e anthocyanin and total phenolic contents of refined flours ranged between 3.9-7.6mug/g and 1299-1607

110 illing resulted useful for the production of refined flours rich in xanthophylls, with particular emp

111 u with MTs in axon-like processes, we used a refined fluorescence decay after photoactivation approac

112 ethods to examine the visual field have been refined from early kinetic perimetry to current standard

113 The modulated structure was refined from the single-crystal X-ray diffraction data w

114 r entirely from processed items extracted or refined from whole foods or synthesized in the laborator

115 improved genome assembly and gene model set, refined functional gene annotation, and anatomical ontol

116 Refined genetic analyses revealed unique haplotype block

117 Refined genetic mapping localizes vitiligo risk in the H

118 es by Whitaker et al. and Lim et al. provide refined genetic tools for dissecting the spatial organiz

119 analysis and may provide the basis for more refined graduation strategies of cartilage degeneration.

120 ating endogenous metabolites after WG versus refined grain (RG) wheat bread consumption.

121 Increased AFV intake and decreased refined grain intake contributed to higher Healthy Eatin

122 Refined grain intake was 0.43 ounce-equivalents/d lower

123 gned to consume a whole grain-rich (WG) or a refined grain-based (RG) diet for 6 wk.

124 le grain-rich diet group (WG) but not in the refined grain-based diet group (RG) (P-diet-by-time inte

125 hole grains plus 40 +/- 5 g dietary fiber/d; refined grain-based diet: 0 g whole grains plus 21 +/- 3

126 No associations were observed between refined-grain intake and infant growth.Higher maternal r

127 ta are lacking.We prospectively investigated refined-grain intake during pregnancy in association wit

128 demographic, lifestyle, and dietary factors.Refined-grain intake during pregnancy was positively ass

129 ain intake and infant growth.Higher maternal refined-grain intake during pregnancy was significantly

130 e effects of diets rich in WGs compared with refined grains (RGs) on immune and inflammatory response

131 Refined grains, a major source of dietary carbohydrates,

132 stern diets (rich in red and processed meat, refined grains, and desserts) with colorectal cancer ris

133 dings for fast foods, carbonated drinks, and refined grains, and high negative loadings for whole fru

134 Western (high in red meat, refined grains, and high-fat dairy) and prudent (high in

135 the effects of substituting whole grains for refined grains, independent of body weight changes, on e

136 nt foods (fruit juices, sweetened beverages, refined grains, potatoes, sweets/desserts) and animal fo

137 thy plant foods (juices/sweetened beverages, refined grains, potatoes/fries, sweets) and animal foods

138 ake of sugar-sweetened and diet soft drinks, refined grains, red and processed meat, and margarine, a

139 , sodium-preserved) meats, and foods rich in refined grains, starch, added sugars, salt, and trans fa

140 2 major food groups, including whole grains, refined grains, vegetables, fruits, nuts, legumes, eggs,

141 The substitution of 1 serving refined grains/d with an equal serving of whole grains d

142 rvings of red meat, processed meat, eggs, or refined grains/wk was associated with significantly lowe

143 cronutrient fortification-mix, added to less refined, high phytate maize meal, would be more effectiv

144 pression profiles for hundreds of tumors, we refined HNSCC subtypes by their malignant and stromal co

145 rence to some case studies we illustrate how refined hypotheses based on taxon-specific traits can pr

146 emonstrated acceptable accuracy and provided refined IgE characterization in 47% of the patients comp

147 The data analysis was started in 2014 and refined in 2015.

148 The displacement model was refined in a supercell as well as in an equivalent comme

149 is score enables the selection process to be refined in the 2 different scenarios of long and short W

150 This basic understanding is refined in the course of development.

151 ions are comparable to those of other crudes refined in the United States because flaring GHG emissio

152 Through refined in vitro reconstitution approaches and multiple

153 and AOX1D wild-type protein activity using a refined in vitro system.

154 me these limitations and have led to new and refined insights into recombination mechanisms, includin

155 gy (ESC) recommendations and the Seattle and refined interpretation criteria.

156 te human behavior and provides an avenue for refined interrogation of the circuits involved in human

157 renewable natural bioactives possible to be refined into chemically standardized mixtures for biolog

158 This refined knowledge is essential to better guide translati

159 ary climate cycles across continents suggest refined lessons for managing genetic diversity in today'

160 for inferring disease transmission to a more refined level than previously.

161 Many of the assay methods needed for refined matrix composition analysis require milligram am

162 Refined measurements of supraglacial DOM and their cycli

163 Consequently, this refined methodology has the potential for much broader a

164 ly involved in human memory and suggest that refined methods are needed to use DBS in these regions t

165 te light chain pairing may benefit from more refined methods to identify and quantify low levels of m

166 Using these refined methods, we efficiently and specifically targete

167 mouse model of cryptosporidiosis, but a more refined model for efficacy is needed.

168 a re-evaluation of published findings and a refined model of IQGAP scaffolding.

169 A refined model of the colchicine site on tubulin was used

170 Altogether, this work provides a refined model of the PRORP-tRNA complex that illustrates

171 This suggests a new refined model of the relationship between LSCs and norma

172 Based on our results, we propose a refined model of transcription initiation by the human m

173 was used to generate hundreds of alternative refined models for the CASP12 experiment, boosting our g

174 In all cases, the LDM-refined models had superior performance in enriching for

175 in providing output for multiple alternative refined models in a way that allows users to quickly vis

176 pare the specific regions of the alternative refined models in which they are most interested e.g. ke

177 connectivities need to be incorporated into refined models of plant cell wall structure, growth and

178 LDM-refined models showed improvement in VS performance over

179 ck and interactive visualization of multiple refined models through the JSmol applet that is equipped

180 plantation into prkdc mutant fish, providing refined models to assess clonal dominance and progressio

181 There is a need for a more refined, molecularly based classification model for glio

182 Coupled with the small refined moments (0.5-1 muB/Fe), this provides a picture

183 sidering the reverse mutation and by using a refined, more reliable data set, based on a new release

184 nderlie the transition from novel actions to refined motor skills.

185 The refined NRG-GBM-RPA consisting of MGMT protein, c-Met pr

186 Then we analyzed partially and fully-refined oils from Italy, Tunisia and Spain.

187 f TPO against the primary oxidation of these refined oils was significantly correlated to their lycop

188 and anisidine value, PV and AV) required for refined oils.

189 The efficacy of TPO in stabilizing refined olive (ROO) and sunflower (RSO) oils was investi

190 revealed synergetic interactions for DF and refined olive oil-bound antioxidants, and antagonistic i

191 ped on multiwell plates, was transferred and refined on the nanostructured substrates.

192 rently unknown how these walls are built and refined or their role, if any, in influencing meristem d

193 We have also refined our analysis by considering specific subsets of

194 We further refined our model to explore how experimentally extrapol

195 ents, although more specific signatures have refined our prognostic abilities.

196 In response to the commentaries, we have refined our suggested model and discussed ways in which

197 Such approaches have already refined our understanding of the alloimmune response and

198 In particular, we highlight how they have refined our understanding of the many protein-based regu

199 It is normally refined out of the opioids that the latex is typically c

200 ount of antioxidants can be preserved in the refined palm oil up to 99%.

201 ch as soybean oil-based interesterified fat, refined palm oil, and palm mid fraction was studied.

202 fined, the process can be iterated using the refined parameters.

203 Biological materials (UVCBs), including many refined petroleum products, present a major challenge in

204 table HCV RNA at follow-up week 24) and used refined phylogenetic analysis of multiple HCV genes to d

205 taxa found, and situations in which aDNA has refined pollen identifications.

206 nded RNAs since 2011, which also support our refined predictions of RNA-like motifs.

207 We refined previously reported associations at 9p24.3 and 1

208 mRNA expression clustering refined prior clustering analyses and identified a poor-

209 rilling and completion, refining, and use of refined products.

210 biomarker aggregation, which may facilitate refined prognostic assessment in the era of precision on

211 ccurate diagnosis, direction of therapy, and refined prognostication.

212 n of integrated processes and to a wealth of refined qualitative and quantitative data.

213 sembly of these beta-sheet peptides has been refined recently.

214 gical conditions can be used to develop more refined regional-scale EF5r estimates required for compi

215 (e.g. morphogens), but how these domains are refined remains unclear.

216 vival of the old solid model but rather as a refined revision of the fluid model, which incorporates

217 tic subtype-specific MRD values allowed more refined risk group stratification.

218 ination of the Ki-67 index and MIPI showed a refined risk stratification, reflecting their strong com

219 IRT2 inhibitors and to the identification of refined, second generation inhibitors.

220 of shell formation in C.gigas, supporting a refined shell formation model including chitin and ECM-r

221 Case study 2 uses this refined simulation method to test for a settlement gap i

222 ated in six commonly used fat/oils in India (refined soybean oil, groundnut oil, olive oil, rapeseed

223 This refined spatial perspective provides unique understandin

224 ed across the four test systems suggest that refined specifications in test guidelines are required t

225 The latest fabrication routes based on refined starting powders and dopants, with innovative si

226 in the IPL are precisely organized in highly refined strata within the IPL.

227 This refined strategy can permit chemical transformations unm

228 For these reasons, more refined structural brain mapping techniques may improve

229 NAs undergo transfer between cells through a refined structural connection.

230 and rR studies have been used to establish a refined structure for the diferric cluster of CmlI(P).

231 t containing annotated phase information and refined structure models.

232 This refined structure provided a significantly improved fit

233 cture sets for analysis, their alignment and refined structure superposition, sequence and structure

234 undus-controlled perimetry allows for a more refined structure-function correlation in diseases with

235 at certain foods, particularly those high in refined sugars and fats, are addictive and that some for

236 lia, the per capita availability of added or refined sugars and sweeteners was shown to have fallen 1

237 diacylglycerol(DAG)-rich oil from a blend of refined sunflower and rice bran oils.

238 he process until it derives a stable list of refined target genes.

239 d techniques provides the potential for more refined, targeted approaches to cardiovascular medicine.

240 To permit more refined targeting, we introduce here the "Killer Zipper"

241 on from no volitional muscle activation to a refined, task-specific activation pattern and movement g

242 with high accuracy, whereas the use of more refined techniques from artificial intelligence enabled

243 interrogated using initial keywords and then refined terms to elicit relevant studies.

244 We furthermore refined the algorithm to handle closely related recipien

245 Here, we refined the association signal, performed conditional an

246 We refined the CC composition and explored PEG and islet-li

247 ed-only haplotype analysis among strains, we refined the chromosome 12E signal to a 1.95 Mb linkage d

248 We refined the features to predictive models (support vecto

249 Here, we refined the genetic basis underlying the functional effe

250 In addition, using this population, we refined the location for 16 out of the 58 known MetaboCh

251 We refined the location of the Red locus to a ~7.2-cM inter

252 in the dioecious plant Silene latifolia and refined the locations of the sex-determining loci on its

253 We further refined the specificity of the proteins identified by co

254 Here, we refined the structure of a ternary protein-protein-RNA c

255 Here, we have refined the technique and incorporated it into a streaml

256 If those parameters can be refined, the process can be iterated using the refined p

257 ve, ascorbate-bound, and GSH-bound forms and refined their resolutions to 1.9, 1.7, and 1.7 A, respec

258 e substantiate this connection and propose a refined theoretical picture.

259 rd initiating clinical trials and developing refined therapies for the muscular dystrophies (MD's) an

260 and trial concepts that will lead to a more refined therapy for this tumour type.

261 holaminergic systems is likely to allow more refined therapy.

262 lculate a tomographic 3D reconstruction, and refined this structure to a final resolution of approxim

263 rectional modulation of PFC activity further refined this subset of brain regions and identified the

264 few months after birth, but is subsequently refined through development.

265 The binding interface was further refined through molecular modeling and mutagenesis and s

266 xcitatory maps is that maps are sculpted and refined throughout development and/or through sensory ex

267 se observations motivate the construction of refined tissue-specific interactomes from organism-speci

268 its X-ray crystal structure in the apo-form (refined to 1.35 A), bound to NAD(+) (1.45 A), and bound

269 he crystal structures of the SR7-SR8 region, refined to 1.8 A, and the SR7-SR9 at lower resolution.

270 r their lexical variants, which were further refined to 25 520 abstracts, 43 253 sentences and 3984 c

271 The MCDR3 locus is thus refined to a shared region of 39 kb that contains DNAse

272 el and stress gradient hypothesis need to be refined to account for this coexistence in drylands.

273 Multiple models have been developed and refined to estimate the overall activation energy and it

274 Current experimental design should be refined to generate clearer evidence, addressing both ag

275 Differential gene expression was refined to identify a core set of genes that defined hyp

276 concept of beta-arrestin-bias may need to be refined to incorporate the selective bias of receptors t

277 s have evolved over decades to become highly refined tools for a broad range of investigations.

278 e and tissue type, providing clinicians more refined tools to evaluate prognosis and treatment.

279 EnCs) propagated using a dual media approach refined towards regulatory compliance showed expression

280 We believe that these refined transcriptional footprints provide a valuable re

281 l heterogeneity will prove more resistant to refined treatment paradigms.

282 ecade have not led to a concomitant shift in refined treatments.

283 Increasingly refined turns are constructed to position malonate half

284 This refined understanding can facilitate better projections

285 This refined understanding can help improve interpretation of

286 One of the key knowledge gaps concerns a refined understanding of the mechanisms that underlie ar

287 Previous work has resulted in a refined understanding, commonly termed the molecular clu

288 Then, the results are refined using our recent advanced model for elastoplasti

289 Crystal structure was refined using Rietveld method and lattice parameters are

290 This emulsion was further refined, using a bed of glass beads (diameter 71mum), th

291 ter added value to the consumers compared to refined vegetable oils.

292 of the AR and GR DNA-binding domains using a refined version of SELEX-seq.

293 tly higher than the whole (664-715mug/g) and refined wheat (109-112mug/g) flour samples by both extra

294 grain wheat (57-449microg/g DM) compared to refined wheat (11-92microg/g DM) breads.

295 be predicted using a general model built on refined wheat (adjusted R2: 0.9986).

296 Refined wheat flour and hulless barley bran (from 9 diff

297 ple was higher than from either the whole or refined wheat flour samples by both extraction procedure

298 The recovery of TPA (74-89%) from whole and refined wheat flours by MAE was significantly lower than

299 renatally; indications for surgery have been refined with evidence, and minimally invasive pyeloplast

300 Top ranked loops are refined with the Rosetta energy function to obtain accur