ライフサイエンスコーパス: regioselectively

1 nes provided the 2-alkylsubstutited products regioselectively.

2 broad functionalities have been synthesized regioselectively.

3 alkenes and gem-difluoromethlylene compounds regioselectively.

4 Cu(I) afford pyrazolo[5,1-c]-1,2,4-triazoles regioselectively.

5 sfer to alkenes forms vinylsilacyclopropanes regioselectively.

6 ford a 2,4,6-trisubstituted pyridine product regioselectively.

7 p from the C-7 hydroxyl of noreugenin to C-8 regioselectively.

8 1,4-dihydro-3(2H)-isoquinolinone derivatives regioselectively.

9 entially produce enolate I, were synthesized regioselectively.

10 erature without any metal catalyst to afford regioselectively 1,5-disubstituted triazolylated pyranos

11 These compounds were made in several regioselectively (13)C-labeled forms, and their structur

12 not give [3,2-c]isoxazoles but rather afford regioselectively [2,3-d]isoxazoles in good yields.

13 ere reacted with terminal alkynes to furnish regioselectively 3,5-disubstituted pyrazoles.

14 n this reaction, levansucrase (LS) transfers regioselectively a fructosyl residue to either C6-OH gro

15 lenging isopropenyl side chain oxidation was regioselectively achieved via a newly developed stepwise

16 pha-chloronorbornene at room temperature, to regioselectively afford the 1:1 addition products exo-1-

17 These alkyne exchange reactions proceed regioselectively and can tolerate a variety of functiona

18 The reactions occur regioselectively and exhibit a notable endo preference,

19 ry and quaternary stereogenic carbon centers regioselectively and in 78-96% ee.

20 ingly, 2-aryl-substituted systems rearranged regioselectively and in a process whose selectivity prov

21 locolchicinoids 15-19, 23, and 25, with high regioselectively and in moderate to good yields.

22 derivatives to produce 2-quinoxalinol imines regioselectively as one isomer in good yield.

23 onoadducts suggests that the addition occurs regioselectively at a 6,6-ring juncture on the surface o

24 llows subsequent chemistry to be carried out regioselectively at one of the two aldehyde groups.

25 reaction with tetracyanoethene, which occurs regioselectively at only one of the rigidly linked dendr

26 The reactions occur regioselectively at position 8 both in 7 and 9-deazapuri

27 Fourth, subsequent bromination proceeded regioselectively at the 15-position to give a trans-(5,1

28 ility to effect double-strand DNA hydrolysis regioselectively at the 3'-O-P bond.

29 of BN anthracene 1 with Br2, however, occurs regioselectively at the 9-position.

30 ed in six steps from thiophene, was arylated regioselectively at the alpha-position directly with iod

31 Ir-catalyzed C-H borylation occurs regioselectively at the C(6) position of B-substituted 1

32 ization steps were very rapid and took place regioselectively at the C-atoms of the C=N bonds, by 5-e

33 uCl4, metallic particles and sheaths deposit regioselectively at the SWNT tips, yielding novel SWNT-m

34 (Z)-1-alkene-1,2-diboronic esters proceeded regioselectively at the terminal C-B bond to afford (E)-

35 The alkylation occurred regioselectively at the terminal oxygen, leading to a si

36 lkyloxy- and dihydroxyoctahydroperylenes are regioselectively available via a new tandem Friedel-Craf

37 ido) hosts (in particular 3a) are capable of regioselectively binding dicarboxylates and pyrophosphat

38 2-hydroxyphenyl)pyridines have been prepared regioselectively by a transition-metal-free, mild, one-s

39 The P450s stereoselectively and regioselectively catalyzed the metabolism of (R)- and (S

40 ion of tryptophan 7-halogenase (PrnA), which regioselectively chlorinates tryptophan.

41 total synthesis of chlorocyclinone A (1) is regioselectively completed in 28 steps.

42 hich flavin-dependent tryptophan halogenases regioselectively control chlorine addition to tryptophan

43 The regioselectively controlled introduction of chlorine int

44 mall molecules and complex natural products, regioselectively controlled libraries, novel one-pot lib

45 A simple and regioselectively controlled method for the preparation o

46 alyzed water-oxidation process is capable of regioselectively converting antibody-bound benzoic acid

47 The deprotected guanidines were subsequently regioselectively cyclized with beta-keto esters yielding

48 ique with (13)C NMR detection was applied to regioselectively deuterated pyridine complexes to invest

49 Various dienes and a triene can be regioselectively diaminated at the internal double bond

50 The investigated catalytic system could regioselectively differentiate the enantiotopic hydroxy

51 demonstrated by the possibility to displace regioselectively each aromatic chloride to introduce div

52 ylenes into propargylic CO bonds of epoxides regioselectively form 1,2-silaoxetanes, which add to ald

53 on of a wide range of substituted alkynes to regioselectively form polycycles containing syntheticall

54 nd electron-acceptor groups were synthesized regioselectively from 2,3,5,6,8-pentachloro-BODIPY, and

55 ers that allow for the growth of each branch regioselectively from any of the hydroxyl positions (5',

56 iacyl sulfolipid and transfers an acyl group regioselectively from one donor substrate molecule to a

57 imer, -tetramer, and -pentamer were obtained regioselectively from their lower homologues, albeit in

58 or internal alkynes in the presence of TiCl4 regioselectively generates substituted naphthalene deriv

59 anide-mediated intermolecular hydroamination regioselectively generates the anti-Markovnikov addition

60 oallylic alkenes cyclize with modest to high regioselectively, generating tetrahydropyrans 40-45, Tab

61 romethylphenyl ether eliminates neutral ArOH regioselectively, giving ionized 2-hexenes rather than i

62 Nature has evolved halogenase enzymes to regioselectively halogenate a diverse range of biosynthe

63 ow the fungal halogenase RadH can be used to regioselectively halogenate a range of bioactive aromati

64 Cytochrome P450cam (CYP101Fe(3+)) regioselectively hydroxylates camphor.

65 id into para-hydroxy benzoic acid as well as regioselectively hydroxylating the 4-position of the phe

66 ons or N-acyloxyiminium ions to be generated regioselectively in a subsequent step.

67 Arrays with the antibodies attached regioselectively in a uniform orientation are typically

68 The reaction proceeds chemo- and regioselectively in an atom-economic way, generating a l

69 ess to a variety of substituted benzosultams regioselectively in excellent yields.

70 ers to give tetrahydrofuran ring stereo- and regioselectively in good yields.

71 5,6-dihydro-2H-pyran-2-acetates stereo- and regioselectively in good yields.

72 e corresponding dianion, which reacts highly regioselectively in the presence of 0.25 equiv of tetram

73 gave 6,6'-dialkoxy-2,2'-bipyridines (6g-k), regioselectively, in excellent isolated yields.

74 n by N-methyl-N-nitrosourea at N7-guanine is regioselectively inhibited by point substitutions of the

75 e formyl and 2-formylvinyl substituents were regioselectively introduced at positions 3 and 20 of Ni(

76 onalization, substituents can be rapidly and regioselectively introduced at the alkaloid C13 position

77 etic polypeptides to be chemoselectively and regioselectively joined together.

78 none substrates, the cyclization takes place regioselectively, leading to either dibenzocyclohepten-5

79 ified to be the C-6 C-methyltransferase that regioselectively methylates pretetramid to yield 6-methy

80 These regioselectively modified particles were desorbed by app

81 cause Gibbs' reagent reacting with different regioselectively modified phenolics displays different c

82 ith heterologous elongation modules afforded regioselectively modified polyketides containing alterna

83 useful precursors for further preparation of regioselectively monosubstituted derivatives of gamma-cy

84 kably, internal homoallyl alcohols delivered regioselectively nonconjugated unsaturated carbonyl comp

85 dition of the N-ethylazomethine ylide occurs regioselectively on a [5,6] double bond on the surface o

86 ogenation conditions, the NH-aziridines were regioselectively opened to the corresponding enantiopure

87 P3A4 adjusts and reshapes the active site to regioselectively oxidize chemically diverse compounds is

88 assessment because it is preferentially and regioselectively oxidized by CYP3A4.

89 Three series of analogs were regioselectively prepared from a protected forskolin pre

90 Indazoles are regioselectively protected at N-2 by a 2-(trimethylsilyl

91 Both require regioselectively protected building blocks that are main

92 The trehalose core was regioselectively protected using a tandem procedure with

93 P-Nitrosophosphate (9) regioselectively reacts with 1-methoxy-1,3-butadiene to

94 the boron trifluoride etherate treatment of regioselectively reduced N-homoallyl imides.

95 the ferric-reductase-like enzyme RbtH, which regioselectively reduces one of the maleic anhydride moi

96 The DMAP unit was shown to regioselectively relay 1,1'-carbonyldiimidazole (but not

97 sformations proceed with stereoretention and regioselectively, responding to bond strength, as well a

98 h copper iodide.TMEDA then allylation occurs regioselectively (S(N)2 mechanism).

99 sformation forms the basis of an approach to regioselectively synthesize substituted isoquinolines vi

100 ed by the 6(I)-O-yl radical, which abstracts regioselectively the hydrogen at C5(II) of the contiguou

101 in we report a domino protocol able to reach regioselectively thiazolylidene systems by combining the

102 pi-Addition proceeds regioselectively through a single transition state to xy

103 lfonyl azides, creating four different bonds regioselectively through N-sulfonyltriazole intermediate

104 hich all reported derivatives add completely regioselectively to [5,6] double bonds.

105 iodomethyl-1,3-dioxanes proceeds rapidly and regioselectively to afford enol ether alcohols by prefer

106 Dihalocarbenes add regioselectively to aryl-substituted benzocyclopropenes

107 IroD hydrolyzes apo MGE (and DGE) regioselectively to give a single linear trimer product

108 ormed in situ to iminium ions formed in situ regioselectively to produce the corresponding propargyla

109 The NO2* radical adds regioselectively to the 4- over the 2-vinyl group but do

110 riments confirm oxidative addition of Pt(II) regioselectively to the least substituted carbon-carbon

111 C-H bond with intermediate A, in some cases regioselectively, to form the neopentylidene-aryl deriva

112 Herein we provide the first series of regioselectively tunable conditions for a Cope rearrange

113 ubstituted naphthalenes are readily prepared regioselectively under mild reaction conditions by the 6

114 ocyclic scaffolds can also be functionalized regioselectively under the developed conditions.

115 mation of propargylamine intermediate, which regioselectively undergoes 6-endo-dig cyclization throug

116 these salts induces ring closure cleanly and regioselectively via formal "exo" addition of the nitrog

117 ,7-diamino-3,6-dibromo-NDI isomer was formed regioselectively, while in DMF under similar reaction co

118 thout TBAF the 2,7-diamino isomer was formed regioselectively, while without TBAF the 2,3-diamino iso

119 robust approach that combines various amines regioselectively with 4,6-dichloropyrone to create subst

120 to give XCF(2)CF(2)CFXY, c-C(3)F(5)Br reacts regioselectively with Br(2) to give a 16.7:1 mixture of

121 h a charge-transfer radical form that reacts regioselectively with O(2) as prescribed by resonance.

122 ted and unactivated aryl chlorides to couple regioselectively with olefins has been developed.

123 iliotoxins was formed stereospecifically and regioselectively, without the use of a directing group o