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1 about how the activity of these proteins is regulated.
2 dered inaccurate and they need to be tightly regulated.
3 differentiation into the NKT cell subsets is regulated.
4 to the nucleoli, suggesting that p-T153/Y155 regulates a previously unappreciated function of TDP-43
6 umber of genes (n = 263) were differentially regulated according to the source of infection, enriched
8 and CLEC3B were significantly differentially regulated across all three -omics levels, confirming the
9 such as the LIM domain kinase (LIMK), which regulates actin activity through phosphorylation of cofi
11 e for the PLCbeta-PKCalpha pathway, possibly regulating activation of SFKs, which are crucial for ini
13 which increased cytosolic Ca(2+) negatively regulates adipokine secretion and have uncovered an evol
14 wing treatment with different drugs known to regulate alpha-SYN expression; while exogenous promoter-
15 trolled in part by RNA-binding proteins that regulate alternative splicing decisions through interact
17 vel long intergenic non-coding RNA with MyoD-regulated and skeletal muscle-restricted expression that
18 d to explore in detail how HIV-1 splicing is regulated and, with moderate throughput, could be used t
20 9% of them during early maturation were down-regulated, and preferentially associated with DNA replic
22 revealed that TrkC-miR2 is significantly up-regulated ( approximately 70 times) in colorectal tumor
23 dentified to be highly sensitive to androgen-regulated AR action, such as NOV and ST6GalNAc1, were ma
24 the CHH context were transcriptionally down-regulated as seeds mature: 99% of them during early matu
28 erellin, GA1, by UV-B in this zone, which is regulated, at least in part, by the expression of GRF1 a
30 ulatory components LKB1 and AMPKalpha, which regulate autophagy induction through their kinase activi
32 dynein-Snapin-mediated retrograde transport regulates BACE1 trafficking in axons and APP processing
34 gra pars compacta and ventral tegmental area regulate behaviours such as reward-related learning, and
36 as neutrophils, we show that FlnA negatively regulates beta2 integrin adhesion to complement componen
38 additional role of environmental factors in regulating birth and mortality rates can lead to erroneo
45 Taken together, we show that the NGB gene is regulated by a cell type-specific loop formed between it
49 hat insulin secretion in pancreatic cells is regulated by Ca(2+) and ROS signaling through Ca(2+)-ind
52 The number of items in working memory can be regulated by external excitation, enabling the system to
59 t to identify novel actin signaling pathways regulated by NPM-ALK, a comprehensive phosphoproteome an
60 performed and 263 genes were differentially regulated by RpoE, and surprisingly, the rseA mutant str
61 Holocene alternates between being primarily regulated by sea ice or glacial discharge from the surro
67 d endoplasmic reticulum, with its expression regulated by the external inorganic carbon concentration
69 at lysosomal functions are transcriptionally regulated by transcription factor EB (TFEB) through the
71 ted that voltage-gated Ca(2+) channels, CaV, regulate Ca(2+) homeostasis in excitable cells following
72 (up to +153%) release, suggesting that down-regulating CAD1 is a promising strategy for improving li
74 inding (Id) proteins play important roles in regulating cardiac development via paracrine signaling.
76 sine kinases acts in signaling pathways that regulate cell migration, cell adhesion, and proliferatio
78 back interactions within the ERK pathway can regulate cell proliferation and transformation, and sugg
79 xicity of Inh2-B1, and its abilities to down-regulate cell wall hydrolase genes and disrupt the biofi
82 at can be transferred to recipient cells and regulate cellular processes in an autocrine or paracrine
83 strating that these enzymes are important in regulating cellular NEIL1 steady state protein levels.
85 vely, our results indicate that ZO-1 binding regulates channel accrual, while disengagement from ZO-1
89 etal dysplasia, identifying a mechanism that regulates chondrogenesis via modulation of SOX9 ubiquiti
91 te a common behavioral output, and that Lef1 regulates circuit development that is fundamentally impo
94 131Arg) variants have an impaired ability to regulate complement activation and may benefit more from
96 roRNA regulation of DCC and suggest that, by regulating DCC, miR-218 may be a switch of susceptibilit
99 ARR activation, and basis by which cytokinin regulates diverse aspects of growth and development as w
100 cleoprotein complexes, and that Lon may help regulate DNA replication in response to growth condition
102 he expression of many miRNAs is dramatically regulated during functional maturation of the mouse visu
103 ed that the biomarker was significantly down-regulated during inflammation induced by acute contact h
105 ng cell-cycle progression itself and must be regulated dynamically during cyclic re-entry to ensure e
108 eviously unrecognized function of the CSN in regulating EGFR neddylation has broad-reaching implicati
109 ate the roles of tumor-associated signals in regulating endothelial cell contractility and adherens j
111 t retinoschisin, the protein encoded by RS1, regulates ERK signaling and apoptosis in retinal cells.
112 et1A catalytic methyltransferase activity in regulating ESC differentiation but not self-renewal and
116 A)-induced AML cell differentiation, through regulating expression of targets such as ASB2 and RARA b
118 tic peptides (NPs), atrial NP and B-type NP, regulate fluid homeostasis and arterial BP through renal
119 rofolate reductase (DHFR) is a key enzyme to regulate folate metabolism, however folate/DHFR activity
121 that members of the Notch signalling pathway regulate further differentiation of the progenitors into
122 sociated with altered expression of proteins regulating GABAergic and glutamatergic signaling in the
123 RF2 demonstrates its role in developmentally regulated gamma-globin gene expression and the ability t
125 Riboswitches are widespread RNA motifs that regulate gene expression in response to fluctuating meta
127 ationale for the powerful ability of BAP1 to regulate gene-environment interaction in human carcinoge
128 tudy, we showed that knockdown of taurine up-regulated gene 1 (TUG1) induces marked inhibition of cel
133 erved significant enrichments of haloperidol-regulated genes in schizophrenia GWAS loci and in schizo
135 s of some markers for AML subtypes and c-MYC regulated genes were considered potential predictors of
139 that MYBS1 and MYBS2 play opposite roles in regulating glucose and ABA signaling in Arabidopsis duri
143 ant interest has emerged in how inflammation regulates HSC fate and how it affects the long-term func
147 genesis in an Egr-2-dependent manner that up-regulates Id2, the repressor of the receptor activator o
148 MEFs lacking AMPK activity also failed to up-regulate IFN-beta and TNF-alpha after treatment with DMX
149 ions in genes encoding protein products that regulate immune function or cell adhesion and tumor cell
151 senescence marker CD57 was significantly up-regulated in CD8(+) T cells from patients with hepatitis
152 little is known about how LMP1 expression is regulated in epithelial cells, and there are conflicting
153 tely expressed genes that are differentially regulated in latent vs. replicative states of infection.
155 of these properties in nanomedicine to down-regulate inflammatory pathways or to be employed as diag
158 gnaling intermediates in murine macrophages, regulating innate immune responses through the initiatio
159 ntify mechanisms through which FGF signaling regulates inner cell mass lineage restriction and cell c
164 nslational modification of HBx by HDM2 which regulates its stability, subcellular localization, and f
165 s a flower-specific jasmonate repressor that regulates JAs, (E)-alpha-bergamotene, TPIs, and a defens
169 gnaling events, such as extracellular signal-regulated kinase 1/2 and label free, in a parallel manne
170 ncluding phosphorylated extracellular signal-regulated kinase, phosphorylated protein kinase B, phosp
175 ry, as well as tegument proteins involved in regulating lytic replication, but lacked capsid proteins
179 roteins and the related SCs of other species regulate meiotic DSB formation to form crossovers crucia
180 ogated not only the alterations in PPARgamma-regulated metabolic pathways, but also the increases in
181 led miR-132 as one of the most severely down-regulated miRNAs at the intermediate and late Braak stag
182 monstrate that the Mdm30-Ubp2-Rsp5 crosstalk regulates mitochondrial fusion by coordinating an intric
184 enous MSK1 levels concomitantly increased to regulate MOR gene expression during neuronal differentia
185 cal models of how the brain selects actions, regulates movement initiation and execution, and switche
188 ctor receptor-associated factor 2 (Traf2) in regulating myocardial necroptosis and remodeling using g
189 ne-protein kinase 2 (Abl2) has a key role in regulating myofiber length, as a loss of Abl2 leads to e
190 osed that SlCBL10 mediates salt tolerance by regulating Na(+) and Ca(2+) fluxes in the vacuole, coope
191 s an important role in antiviral immunity by regulating natural killer and CD8(+) T cells, epigenetic
192 eloping vertebrate nervous system evolved to regulate neurogenesis.SIGNIFICANCE STATEMENT The Src fam
197 editing occurred, generating B cells with up-regulated Nod1, including follicular and marginal zone B
198 proteins are histone demethylases that both regulate normal cell fates during development and contri
199 SF30-L mediates nitrate signaling in part by regulating NRT1.1 expression, thus adding an important c
202 lular and the extracellular microenvironment regulating oligodendrocyte properties and discuss stem c
203 teracts with DAXX and, in turn PTEN directly regulates oncogene expression by modulating DAXX-H3.3 as
206 (+) T cells, suggesting that miR-155 and ICB regulate overlapping pathways to promote antitumor immun
210 ation, chromosome condensation and precisely regulated partitioning of chromosomes into daughter cell
211 udy uncovers a novel molecular mechanism for regulating PD-L1 protein stability by a cell cycle kinas
214 el in which dorsoventral genes coordinate to regulate plant development by localizing auxin response
215 has been shown to interact with nephrin and regulate podocyte cytoskeleton and slit diaphragm dynami
216 e goal should be to prohibit or more closely regulate potentially injurious ingredients and thus prom
217 that piRNAs and piRNA biogenesis components regulate precursor mRNA splicing of P-transposable eleme
218 ow vascular endothelial growth factor (VEGF) regulates PRKCB promoter function in CLL cells, stimulat
220 is a host defense response that directly up-regulates production of keratin-derived AMPs (KAMPs) by
221 These results together suggest that NRTIs up-regulate proinflammatory cytokines via a Wnt5a signaling
222 hyll switch; pufQ is found within the oxygen-regulated pufQBALMX operon encoding the reaction centre-
223 mportant role of litter-leached DOC input in regulating rain-induced soil CO2 pulses and microbial co
224 understanding of the mechanism by which IreB regulates resistance, we initiated a structure-function
232 results demonstrate how sensory information regulates state-dependent reflexes in the lower urinary
234 ndings of the compounds' unique abilities to regulate stem cell fate provides opportunities for devel
239 the structure as a thermostat that uniformly regulates thalamic activity through negative feedback.
240 in olfactory bulb (MOB), inhibitory circuits regulate the activity of principal cells precisely to dr
241 sulting in downstream activation of STAT3 to regulate the balance between IL-12/IL-23 subunits causin
243 ls and the mechanisms by which these signals regulate the disruption of avascular privilege in photor
244 In addition, we verified miR-449b could regulate the expression levels of CDK6, c-MYC, HDAC1 and
246 lational modifications have been reported to regulate the function of epidermal growth factor recepto
247 odification and ubiquitin-proteasome systems regulate the major events of meiotic prophase in mouse.
250 on: Is there an optimal feedback strategy to regulate the synthesis of a protein to ensure that an ev
251 gi of hair cells, suggesting that Tomt might regulate the trafficking of other MET components to the
252 proposed to function downstream of mTORC1 to regulate the translation of 5'TOP mRNAs such as those en
253 NS is well recognized, how these progenitors regulate the vasculature outside the CNS remains largely
257 hosphorylation provide a phospho-switch that regulates the cellular activity of ATG4B to control LC3
259 ether the microtubule-associated protein tau regulates the differentiation and survival of mDANs duri
261 difying enzyme histone deacetylase 3 (Hdac3) regulates the formation of both lymphovenous valves, whi
262 ecifically, we found that GnT-III expression regulates the levels and activation of the heavily glyco
263 l migration.Adenomatous polyposis coli (APC) regulates the localization of some mRNAs at cellular pro
264 that PTH1R signaling directly and indirectly regulates the paracellular Ca(2+) transport pathway by m
266 the physiological role of the type-B ARRs in regulating the cytokinin response, mechanism of type-B A
267 t endogenous GDNF plays an important role in regulating the function of dopamine transporters in the
269 otic spindle into a polar body by negatively regulating the rho pathway rather than through direct in
270 hedral capsids of specific size and shape by regulating the spatial arrangement of the hexameric and
271 of Nt17 post-translational modifications in regulating the structure and aggregation of Httex1 and s
274 s interact with other cell types to actively regulate their extracellular environments for tissue mai
275 ic regulatory T cells directly or indirectly regulate their influx by altering the chemotactic milieu
276 tes to produce proinflammatory cytokines, up-regulated their C5aR and FcRIII expression, and released
278 ative pathway proteins or the molecules that regulate this pathway were detected in 71% of the women,
279 f integrin tension was shown to be spatially regulated through two myosin-signaling pathways, myosin
281 n of the promoter and 5'-UTR of the androgen-regulated TMPRSS2 (transmembrane protease, serine 2) gen
282 o ask questions about how these cells can be regulated to mitigate the collateral destruction associa
284 sition of mRNAs can alter gene expression by regulating transcript localization, stability and/or tra
288 ce of context-specific H3K4 methylation that regulates transcriptional outputs during ESC pluripotenc
292 e SLCF-mediated apnea and bradycardia via up-regulating TRPV1 expression and excitation of laryngeal
293 LL-associated factor 2 (EAF2) is an androgen-regulated tumor suppressor and its intracellular localiz
294 croarray analysis C-82 treatment strongly up-regulated two clusters of genes that correlate negativel
297 f the transmembrane receptor NOTCH1 directly regulates vascular barrier function through a non-canoni
298 s in the extracellular matrix can direct and regulate vaspin interaction with target proteases or oth
300 ins with the small modifier, ubiquitin (Ub), regulates virtually every known cellular process in euka
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