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1 to specify the B-cell lineage, bound to and regulated the expression of 109 lncRNAs in pro-B and mat
4 11 expression quantitative trait loci (eQTL) regulating the expression of 4105 genes, including nine
5 osteosarcoma U2OS cells, we found that SRSF3 regulates the expression of 60 genes including ERRFI1, A
8 that RD26 can act antagonistically to BR to regulate the expression of a subset of BES1-regulated ge
9 tor 1 (IRF-1) is a transcription factor that regulates the expression of a broad range of antiviral h
11 ucho (Gro) is a Drosophila co-repressor that regulates the expression of a large number of genes, man
12 tein clustered mitochondria homologue (CLUH) regulates the expression of a mitochondrial protein netw
13 For example, Arabidopsis MAP kinase 4 (MPK4) regulates the expression of a subset of defense genes vi
15 riaceae, have been implicated in dynamically regulating the expression of a large number of genes upo
16 abditis elegans' life span by differentially regulating the expression of a specific insulin-like pep
17 lling the turnover of basal keratinocytes by regulating the expression of a subset of genes involved
18 cell fate determination and tumorigenesis by regulating the expression of a wide range of target gene
19 vidence that MvfR may also bind and directly regulate the expression of additional 35 loci across the
20 stration of rosiglitazone in T1DM-2W mice up-regulated the expression of AdipoR1 and restored the neu
21 in a non-coding distal enhancer element that regulates the expression of alpha-synuclein (SNCA), a ke
22 bin gene, its enhancers, and POL3RK gene for regulating the expression of alpha-globin in silent cell
23 se lacking STP2, a transcription factor that regulates the expression of amino acid permeases, are im
26 rs12459419 C>T in the splice enhancer region regulates the expression of an alternatively spliced CD3
27 not in the dksA mutant, suggesting that DksA regulates the expression of an unknown cofactor(s) requi
28 production in some transgenic lines by down-regulating the expression of an activator of anthocyanin
29 he JAZ2 targets MYC2, MYC3 and MYC4 directly regulate the expression of ANAC19, ANAC55 and ANAC72 to
31 er, RANK signaling in tumor cells negatively regulates the expression of Ap2 transcription factors, a
33 Detect was used to identify novel TF modules regulating the expression of Arabidopsis (Arabidopsis th
35 inal NPXY motifs, LRP1 beta-chain positively regulates the expression of ATP binding cassette transpo
36 negative regulator, Keap1 and is able to up-regulate the expression of autophagy-associated proteins
38 wth response gene 2 (EGR2) and EGR3 directly regulate the expression of Bcl6 in Tfh cells, which is r
40 euronal activity and energy metabolism, also regulates the expression of BDNF, which is intimately as
42 on factors including Gli1, Atoh1 and REST to regulate the expression of both oncogenes and tumor supp
43 c-helix-loop-helix transcription factor that regulates the expression of CBF genes, and the phosphory
44 triggered by LPS, as both agents oppositely regulate the expression of CCL19 and TRIB3 Besides, palm
47 ead ZHOUPI indirectly triggers cell death by regulating the expression of cell wall-modifying enzymes
48 ovis bacillus Calmette-Guerin infection down-regulated the expression of CIITA/MHC-II by inducing hyp
49 et al. (2017) reveal that the gut microbiota regulates the expression of circadian-clock genes to imp
50 hromatin occupancy analyses reveal that Pdx1 regulates the expression of Clec16a, a type 1 diabetes g
51 8 influences flowering time through directly regulating the expression of cmo-MIR156 in the aging pat
53 Here, we show that Drosophila FOXO (dFOXO) regulates the expression of core small RNA pathway genes
54 stroma plays an important role in negatively regulating the expression of CXLC12 on osteoblasts and t
56 es the retinoid X receptor, which reportedly regulates the expression of cytochrome P450 aromatase (P
57 ed genes suggested that FoxQ1 may negatively regulate the expression of Dachshund homolog 1 (DACH1),
59 ruited by specific transcription factors and regulate the expression of developmentally important gen
60 uronal cell types; play an important role in regulating the expression of developmentally important g
63 tiation and the dedifferentiation of INPs by regulating the expression of distinct target genes at di
64 metabolic gene expression, functions to down-regulate the expression of diverse genes encoding secret
65 g chick otocysts, we show that BMP signaling regulates the expression of Dlx5 and Hmx3, both of which
66 that Ilk controls branching morphogenesis by regulating the expression of DUSP8, which inhibits p38MA
67 pression quantitative trait loci (eQTL) that regulate the expression of Egfr between female and male
69 ng it was demonstrated that Snail positively regulated the expression of EndMT markers (Slug, N-cadhe
70 r stress-sensitive transcription factor that regulates the expression of enzymes which have previousl
71 ng proliferation and cytokine production and regulating the expression of epithelial cytokine recepto
72 intenance of a basal epithelial phenotype by regulating the expression of epithelial-specific genes i
74 is necessary but probably not sufficient to regulate the expression of eve and run-1 Our study there
75 show that inhibition of Notch1 signaling can regulate the expression of fatty acid oxidation genes an
76 w that Transient Receptor Potential (TRP) C3 regulates the expression of fibronectin, a key regulator
77 Together with a second ATPase, FleN, FleQ regulates the expression of flagellar and exopolysacchar
79 la Pathogenicity Island (FPI) and positively regulating the expression of FPI genes, which encode a T
80 alyses have revealed that WNT5a acts to down-regulate the expression of FSH-responsive genesin vitro,
81 ernative splicing functions as a switch that regulates the expression of functionally distinct DmNmna
82 g RNA molecules whose primary function is to regulate the expression of gene products via hybridizati
83 ndicated that compound 1 and DBL exposure up-regulated the expression of gene mcyB and down-regulated
84 highly homologous transcription factors that regulate the expression of genes bearing antioxidant-res
85 ons between these transcription factors also regulate the expression of genes encoding proteins that
87 -like family of transcription factors (KLFs) regulate the expression of genes involved in cell prolif
89 downstream reactive sulfur species (RSS) and regulate the expression of genes mediating sulfide homeo
90 X6 isoforms differentially and cooperatively regulate the expression of genes specific to the structu
91 y of hypoxia-inducible factors (HIFs), which regulate the expression of genes that contribute to angi
92 t, neurons must sense activity over time and regulate the expression of genes that control these para
93 in the nucleus of vitamin D target cells to regulate the expression of genes whose products control
94 c investigations revealed that NURF directly regulated the expression of genes encoding immunoproteas
95 gulated the expression of gene mcyB and down-regulated the expression of genes ftsZ, psbA1, and glmS
96 icated that TDCIPP exposure significantly up-regulated the expression of genes involved in endoplasmi
97 (Glyco(Lo) mice) lowered glycolytic rate and regulated the expression of genes known to promote cardi
99 master xenobiotic receptor that coordinately regulates the expression of genes encoding drug-metaboli
100 ator 1 (Mxr1p) is a zinc finger protein that regulates the expression of genes encoding enzymes of th
101 induced the transcription factor Nrf2, which regulates the expression of genes encoding heme oxygenas
102 neage commitment of T cell precursors, Foxn1 regulates the expression of genes involved in antigen pr
103 scription factor WRINKLED1 (WRI1) positively regulates the expression of genes involved in fatty acid
104 formation of a transcriptional complex that regulates the expression of genes involved in integument
107 (Foxo3a) physically interacts with Tet2 and regulates the expression of genes related to aNSC prolif
109 ed Tat plays a dual role in HIV infection by regulating the expression of genes belonging to the viru
111 mation of prefrontal cortical minicolumns by regulating the expression of genes involved in early spo
112 e molecular pathways involved and mechanisms regulating the expression of genes involved in inflammat
113 AP2 (ApiAP2) family, that is responsible for regulating the expression of genes involved in RBC invas
114 inhibited gene expression, specifically down-regulating the expression of genes of the late cornified
115 e and regulates adipocyte differentiation by regulating the expression of genes related to insulin se
116 metabolic reprogramming of naive T cells by regulating the expression of glucose transporters, glyco
119 sense iron levels in the blood to positively regulate the expression of hepcidin through activation o
120 jaw (maxilla)-to-mandible transformation by regulating the expression of homeobox transcription fact
121 ctures that interact with the same ligand to regulate the expression of homologous genes in different
123 beta-heterodimeric transcription factor that regulates the expression of hundreds of genes in a tissu
124 ntial, pleiotropic transcription factor that regulates the expression of hundreds of genes-is disprop
126 HIF1-alpha accumulation in nuclear; and down-regulated the expression of hypoxia-associated transcrip
127 maRIIIa-mediated co-signal differentially up-regulated the expression of IFN pathway genes compared w
130 ucosal immunity and commensal homeostasis by regulating the expression of IL-22 and the antimicrobial
132 matin has emerged as a promising approach to regulate the expression of important disease-relevant ge
133 ysis, we found that in CLL cells, HIF-1alpha regulates the expression of important chemokine receptor
134 model wherein KLK5-mediated PAR-2 activation regulates the expression of inflammation-associated mRNA
136 Our findings indicate that specific miRNAs regulate the expression of inflammatory cytokines in hum
137 d its phenotype toward pro-atherogenic by up-regulating the expression of inflammatory genes and down
138 , WhiB3 regulates intraphagosomal pH by down-regulating the expression of innate immune genes and blo
141 is at nutritional Se levels not only by down-regulating the expression of integrin beta3 but also by
142 antiviral host factor in hepatocytes, which regulates the expression of interferon (IFN)-stimulated
143 d synaptic input, as evidenced by UNC-3 also regulating the expression of ionotropic neurotransmitter
144 duced by Treg cells at an autoimmune site up-regulates the expression of its own receptor, CCR8, on t
145 sed in microarray analysis, DHI treatment up-regulated the expression of kallikrein and plasma kallik
146 ecules work in part through their ability to regulate the expression of key leukocyte adhesion molecu
148 the ten-eleven translocation 2 (TET2) enzyme regulates the expression of key cardiac genes, such as M
149 anscriptomic analyses showed that glycolysis regulates the expression of key genes involved in cardia
150 valve is under the control of NOTCH1, which regulates the expression of key pro-osteogenic genes suc
151 p53 controls DNA methylation homeostasis by regulating the expression of key counteracting component
152 gas disease by modulating ROS production and regulating the expression of key physiological regulator
153 ther downstream and control LR production by regulating the expression of LATERAL ORGAN BOUNDARIES-DO
154 Moreover, macroH2A1 isoforms differentially regulate the expression of lipogenic genes by modulating
156 rtant role in endometrial decidualization by regulating the expression of major decidual marker genes
158 -variable regulon) to rapidly and reversibly regulate the expression of many genes, which include kno
161 cing in macrophages, we discovered that IRE1 regulates the expression of many proatherogenic genes, i
162 F-2 is of special significance because it co-regulates the expressions of mediators of energy metabol
166 was to elucidate the mechanism by which VEGF regulates the expression of miR-17-92 cluster in ECs and
168 to traverse through maturation steps and in regulating the expression of most Tcf1 target genes.
170 involved in cancer and immunity and known to regulate the expression of mRNAs differentially expresse
172 duction and biliary cholesterol excretion by regulating the expression of Mtp and Abcg5/Abcg8 via Shp
173 cooperated with DNA methylation to directly regulate the expression of multiple germ cell-specific g
174 nt 32 (RGC32) is a transcription factor that regulates the expression of multiple genes involved in c
176 The serine 215 residue, which is known to regulate the expression of Mxr1p-activated genes in a ca
178 hat many lncRNA loci act locally (in cis) to regulate the expression of nearby genes-for example, thr
179 in the population, and the number of repeats regulates the expression of nearby genes (known as expre
181 s gene, with or without the loss of elements regulating the expression of neighboring genes, are the
183 inly from the salvage pathway, by positively regulating the expression of Neu3, the gene encoding neu
185 nt in the second intron of Notch1 locus) and regulates the expression of Notch1 in ventral NSPCs of t
186 tion (PPI) in vitro and in live cells and up-regulate the expression of Nrf2-dependent gene products.
188 formation of giant multinucleated OCs by up-regulating the expression of nuclear factor of activated
189 ic explanation for the ability of lncRNAs to regulate the expression of numerous genes distributed ac
190 oth endogenous and exogenous PGC-1alpha down-regulate the expression of numerous genes encoding secre
191 L1 TFs work in tandem with KNOTTED1-types to regulate the expression of numerous target genes involve
193 een HMGNs and H1 in chromatin epigenetically regulates the expression of OLIG1&2, thereby affecting o
201 tion factor Nr2e3, Photoregulin1 (PR1), that regulates the expression of photoreceptor-specific genes
202 ION RESPONSE1, the main transcription factor regulating the expression of Pi starvation-induced genes
203 ations, we find that vegfaa mutant hearts up-regulate the expression of potentially compensating gene
204 zoid and caulonema development by positively regulating the expression of PpLRL1 and PpLRL2, the two
205 es the induction of neural-specific genes by regulating the expression of PRC2 complex components.
207 1) QSI resistance spreads when QS positively regulates the expression of private or quasi-public good
208 mily proteins are transcription factors that regulate the expression of pro-inflammatory cytokines an
212 hat JAK1-mediated signaling cascades in skin regulate the expression of proteases associated with the
215 ntified a new cellular pathway in which ATF4 regulates the expression of RhoGDIalpha that in turn aff
216 uggest that the OT system may play a role in regulating the expression of schizophrenia spectrum diso
217 We show that SMARCE1 drives invasion by regulating the expression of secreted proteases that deg
218 r, EMP2 expression correlates with and helps regulate the expression of several cancer stem cell asso
220 chanistically, upon CXCL12 exposure, SC down-regulated the expression of several pain-associated targ
224 tein U (hnRNP U), plays an important role in regulating the expression of SLO-2 (a homolog of mammali
228 or in mediating the hypoxic response by down-regulating the expression of specific genes, including A
229 Further experiments showed that DARPP-32 regulates the expression of SRp20 splicing factor and co
232 s activated by the phosphatase Glc7, and can regulate the expression of target genes in concert with
236 four alternatively spliced transcripts that regulate the expression of TH2 cytokines, IL-4, IL-5 and
237 identified gene has been shown to negatively regulate the expression of the caffeine metabolism genes
238 ligand, on the promoters and differentially regulate the expression of the endogenous AR target gene
239 4, Prox1, Sox1, and a few additional factors regulate the expression of the lens structural proteins,
240 g (RS) pathways converge antagonistically to regulate the expression of the nuclear-encoded transcrip
241 uggesting that Znf2 and Pum1 each positively regulate the expression of the other to achieve the fila
244 echanistically, we found that PDGF signaling regulated the expression of the E2F transcription factor
246 we observed that c-Met induction markedly up-regulated the expression of the negative co-stimulatory
247 ng through the receptor tyrosine kinase Ret, regulates the expression of the chemosensory fate determ
249 roduction of the anaphylatoxin C3a, and down-regulates the expression of the Foxp3 gene and anergy-re
250 med IB4 cells by RNA interference negatively regulates the expression of the genes downstream of LMP1
252 echanistically, we show that AMPK negatively regulates the expression of the integrin-binding protein
254 required for HSPC specification and that it regulates the expression of the Notch ligand Jagged1a in
255 de transcriptional analysis shows that NO up-regulates the expression of the plastid nitrite reductas
257 e polycomb repressive complex 1, BMI1, which regulates the expression of the schizophrenia-related ge
258 As showed that Pacman post-transcriptionally regulates the expression of the secreted insulin-like pe
259 l gene which regulates coffee consumption by regulating the expression of the genes linked to caffein
260 of HA levels in cell culture and in vivo by regulating the expression of the HA synthase HAS3 and tw
261 We conclude that miRNAs are involved in regulating the expression of the major T1D autoantigens.
262 tion and survival of the seeded ASCs, and up-regulates the expression of their neurotrophic factors m
266 ontexts, yet the cis and trans elements that regulate the expression of these enzymes remain essentia
271 /BZR1 family of transcription factors, which regulate the expression of thousands of downstream genes
272 eracting with co-factors that enable them to regulate the expression of thousands of genes linked to
277 nce that (1) growth arrest-specific 6 (Gas6) regulates the expression of tissue factor during venous
280 epatocytes that express HCV-NS5A in liver up-regulate the expression of Toll-like receptor 4 (TLR4),
281 this study, we determined whether TGF-beta1 regulated the expression of TREM-1 in a mouse model of p
282 SUMO does not modify Oct-1 directly, but regulates the expression of TRIM21 that enhances Oct-1 u
284 In addition, we observed that LPS itself up-regulated the expression of TSG6 in TSG6(+/+) mice, sugg
286 onal novel molecular mechanism by which LMP1 regulates the expression of tumor-promoting host genes.
288 aling keeps Ras targets in check by directly regulating the expression of two key downstream transcri
289 phocyte progenitors and immature lymphocytes regulates the expression of ubiquitous and lymphocyte-sp
290 lpha) controls BAT-mediated thermogenesis by regulating the expression of Ucp1 Inhibitor of different
292 serve as secondary signaling messengers that regulate the expression of various inflammatory mediator
294 sequently, we found that cyclin F negatively regulates the expression of viral protein Vif (viral inf
296 NAs) play vital roles in viral infections by regulating the expression of viral or host genes at the
297 hich can interact with the ClpAS-P system to regulate the expression of virulence factors and pathoge
299 human gingival fibroblasts (GFBLs) strongly regulated the expression of wound healing-related genes.
300 ucleotide excision repair through positively regulating the expression of xeroderma pigmentosum compl
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