ライフサイエンスコーパス: regulator

1 dies, we identify FKBP12 as a novel hepcidin regulator.

2 OS3, and SOX17) and the RREB-1 cell adhesion regulator.

3 eceptor AXL, an important inhibitory DC auto-regulator.

4 tiple cell types by the same transcriptional regulator.

5 cal-induced proximity of a desired chromatin regulator.

6 leading to the identification of new growth regulators.

7 uba and ARHGAP10, two Golgi-associated Cdc42 regulators.

8 nd identifies biologically meaningful master regulators.

9 expression of Eya1 is controlled by upstream regulators.

10 sorders, as well as networks of upstream RNA regulators.

11 etic regulation of key cardiac transcription regulators.

12 te of receiver domains of bacterial response regulators.

13 bryo surrounding factor (ESF1) developmental regulators.

14 the canonical WUSCHEL-CLAVATA meristem size regulators (3) .

15 ies a protein complex linking key epigenetic regulators acting in the molecular control of embryonic

16 ucing peptides (AIPs) and the accessory gene regulator (agr) operon to coordinate expression of virul

17 The autoimmune regulator (AIRE) protein is the key factor in thymic neg

18 abditis elegans larvae, the master metabolic regulator AMP-activated protein kinase (AMPK) plays a cr

19 established network biology approach (master regulator analysis) to combine a transcriptional signatu

20 a light-sensing B12-binding transcriptional regulator and demonstrated that it controls folate and u

21 ntified activated STAT3 as a transcriptional regulator and revealed differential expression of STAT3

22 nalysis showed inhibition of proinflammatory regulators and activation of anti-inflammatory pathways

23 berculosis Both genes encode transcriptional regulators and are adjacent to orthologs of the mmpS5-mm

24 We explore potential regulators and find a role for HSF1 in the induction of

25 The BET proteins are major transcriptional regulators and have emerged as new drug targets, but the

26 , our method ensures the existence of master regulators and identifies biologically meaningful master

27 membrane-anchored TGF-beta family signaling regulators and link membrane association with their sign

28 evealed a complex network of transcriptional regulators and pathways that orchestrate the cellular re

29 Regulators and payers have contrasting priorities that c

30 en an expansion in knowledge of new cellular regulators and roles of CRTCs beyond CREB.

31 EMT) by driving expression of the master EMT regulators and stem cell markers.

32 Analyses with 11 actin regulators and three actin-targeting drugs suggest that

33 asic research as well as the general public, regulators, and industry.

34 investors, technology providers, utilities, regulators, and other stakeholders to accelerate the ado

35 ncRNA-Cox2 and lincRNA-AK170409 as NF-kappaB regulators, and this tool will be useful for identifying

36 ver, recent studies indicate that the master regulators are often coexpressed.

37 , sequence analysis indicates that FisR-type regulators are relatively common for controlling sulfide

38 nges in the cis-regulatory elements of these regulators are thought to constitute the major driver of

39 iption factor is an ortholog of the stomatal regulator AtMUTE, which defines GC precursor fate in Ara

40 ly with the SH3 domain of the Arp2/3 complex regulator Bbc1.

41 ersely, conditional deficiency of the master regulator Bcl6 in CD4(+) T cells resulted in a marked re

42 In cases where the central regulator benefits from the polluting activity, we argue

43 of the CRP/FNR super-family of transcription regulators) bound at a single DNA site to act as a dual

44 of cystic fibrosis transmembrane conductance regulator (CFTR or ABCC7; i.e., G551D, S1251N, and G1349

45 he Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene affect CFTR protein biogenesis or

46 th most common cystic fibrosis transmembrane regulator (CFTR) mutation that causes cystic fibrosis.

47 he cystic fibrosis transmembrane conductance regulator (Cftr).

48 rk of helix-loop-helix (HLH) transcriptional regulators controlled by MYT1L, as indicated by our anal

49 e role of the S. agalactiae global virulence regulator, CovR, in UTI pathogenesis is unknown.

50 described contributions of the recombination regulator Cst9 (also known as Zip3).

51 Here, we show that the cell cycle regulator, cyclin-dependent kinase 2 (CDK2), couples pri

52 g to localize 14 S. pombe SPB components and regulators, determining both the relationship of protein

53 er antigen-reactive T cells deficient in the regulator diacylglycerol kinase zeta (DGKzeta) with or w

54 l cycle and reduced expression of cell cycle regulators during the initiation stage of reprogramming.

55 al targets include cell cycle and epigenetic regulators (e.g., Foxo3, Plk1, Mycn, Dnmt1, Dnmt3b, and

56 e, the conserved metabolic and developmental regulator ESRRA was highlighted for an especially early

57 subtypes and posit MYD88/p100 signaling as a regulator for B-cell activation.

58 on of Hnf4a as the potential transcriptional regulator for Dnajc22 which was further corroborated usi

59 9 to USP7 and showed that USP7 is also a key regulator for monoubiquitination at H2A Lys-119 as both

60 inhibits the expression of ComK, the master regulator for the K-state, and reduces transformability.

61 c contacts with the excluded strand act as a regulator for unwinding activity.

62 sregulated genes uncovered distinct MEF2A co-regulators for the atrial and ventricular gene sets, and

63 mplex between 14-3-3 and the stress response regulator GCN1, inducing GCN1 turnover and neurite outgr

64 and new roles for unphosphorylated response regulators have been identified.

65 in cancer by dual targeting of the negative regulators HDM2 and HDMX.

66 exosomes are emerging as antitumor immunity regulators; however, their effects on secondary exosome

67 The sensor-regulator hybrid SagS plays a central role in biofilm de

68 Most positive regulators identified in our screens, including Rab34, P

69 ur in silico search for post-transcriptional regulators identified miR-495 as a novel regulator of mu

70 ntry of the NuRD-interacting transcriptional regulator Ikaros into mouse pre-B cell nuclei triggered

71 p diseases, functions, pathways and upstream regulators implied that a common underlying mechanism li

72 Overall, our results identify RXR as a regulator in the myeloid cell-assisted metastatic proces

73 tif analysis, can be used by researchers and regulators in a hazard screening capacity to assess the

74 ved combinatorial associations of additional regulators in a lineage- and stage-specific context.

75 TCRs and CARs suggested a role for negative regulators in both systems.

76 helps us to understand the role of chromatin regulators in brain development, plasticity, and gene ex

77 (ap1) alleles in a mutant screen for floral regulators in C. hirsuta.

78 dicated that lncRNAs are emerging as crucial regulators in cancer processes and potentially useful as

79 Identification of over 500 epigenetic regulators in humans raises an interesting question rega

80 teric pathogen of humans, the roles of these regulators in pathogenesis are less known.

81 VERNALIZATION2, loci identified as flowering regulators in the domesticated crops wheat and barley.

82 Among these targets were actin regulators, including the tumor suppressor eplin.

83 ons upstream of wetA, vosA and velB, the key regulators involved in conidial maturation.

84 r investigation of drugs targeting chromatin regulators is warranted in HPV-negative HNSCCs driven by

85 Histone deacetylase-2 (HDAC2), an epigenetic regulator, is critical for stress-induced cardiac hypert

86 LL4), an embryonic stem cell transcriptional regulator, is re-expressed by an unknown mechanism in po

87 Although KANK1 is known as a cytoskeleton regulator, its tumorigenic function in MPNSTs remains la

88 e transcription factor Nrf2 and its negative regulator, Keap1 and is able to up-regulate the expressi

89 e proliferation also involves the cell cycle regulator KIP-RELATED PROTEIN2 and ABERRANT LATERAL ROOT

90 establish CTRP6 as a novel metabolic/immune regulator linking obesity to adipose tissue inflammation

91 We find that while these regulators maintain mostly independent control over dist

92 These epigenetic regulators may act to facilitate the expression and/or r

93 Here we report the key autophagy regulators modulated by diabetes in the murine developin

94 The discussion of serotype-specific regulator mutations focuses on serotype M3 GAS isolates,

95 icians (n = 3), journal editors (n = 9), and regulators (n = 2) (3 participants were included in 2 gr

96 heir antagonistic effect on the pluripotency regulator Nanog.

97 Utilization of negative checkpoint regulators (NCRs) for cancer immunotherapy has garnered

98 twork controlled by the fungal transcription regulator Ndt80.

99 Together, these data define METTL3 as a regulator of a chromatin-based pathway that is necessary

100 ic genetic interaction with Hac1, the master regulator of a second proteotoxic stress response, the u

101 arin-Dorfman syndrome, is a highly conserved regulator of adipose triglyceride lipase (ATGL)-mediated

102 vate kinase muscle isozyme 2 (PKM2) is a key regulator of aerobic glycolysis.

103 ts suggest a novel role for EMCN as a potent regulator of angiogenesis and point to its potential as

104 diting technology to silence VEGFR2, a major regulator of angiogenesis, in retinal endothelium and ab

105 Beclin 1 (BECN1) is a key regulator of autophagy, a critical catabolic homeostasis

106 eted in Colorectal Cancer (DCC), is a master regulator of axonal crossing throughout the neuraxis.

107 ostate cancer in which it acts as a negative regulator of BET protein stability and also provide a mo

108 NDPK-C is a novel critical regulator of beta-adrenoceptor/cAMP signaling and cardia

109 of dedifferentiation and highlight SOX5 as a regulator of beta-cell phenotype and function.

110 e contribution of CD69 as a nonredundant key regulator of BIC/miR-155-dependent Treg cell development

111 ransporters and cytochrome P450 7a1, the key regulator of bile salt synthesis, indicating that elevat

112 Our data identify GFRAL as a new regulator of body weight and as the bona fide receptor m

113 plasmic adapter molecule that is an upstream regulator of both IkappaB kinase (IKK) and c-Jun N-termi

114 e we show that oncogenic miR-182 is a strong regulator of C/EBPalpha.

115 jury, SCI induced upregulation of the native regulator of CaN 1 (RCAN1) in the DRG at the transcript

116 pression analysis for eight SEP-like GERBERA REGULATOR OF CAPITULUM DEVELOPMENT (GRCD) genes, includi

117 Our findings identify PABPC1 as a direct regulator of cardiac hypertrophy and define a new paradi

118 e of ZBP1 as a pathogen sensor and a central regulator of cell death and inflammatory responses.

119 -interacting protein kinase 1 (RIPK1), a key regulator of cell death, NF-kappaB, and MAPK signaling.

120 ing environment has been implicated as a key regulator of cell differentiation, migration, and prolif

121 PML is a tumour suppressor and regulator of cell differentiation.

122 nger complex (CPC) is a conserved, essential regulator of cell division.

123 cover Nudt21 as a novel post-transcriptional regulator of cell fate and establish a direct, previousl

124 of rapamycin complex 1 (mTORC1) is a central regulator of cell growth that responds to diverse enviro

125 chromatin fibre and block the binding of the regulator of chromatin condensation 1 (RCC1) acidic patc

126 bound at a single DNA site to act as a dual regulator of cmr transcription and an activator of the d

127 u transporter, a lysosomal Cu exporter, or a regulator of Ctr1 activity, but its functional and evolu

128 ional activities, implicating M as a primary regulator of cytopathicity and host transcriptional supp

129 ype R2R3-MYB transcription factor MYB15 as a regulator of defense-induced lignification and basal imm

130 53BP1 is a key regulator of DSB repair pathway choice in eukaryotic cel

131 ious work established that Lis1, a conserved regulator of dynein, binds to its motor domain and induc

132 pression of transcription factor Slug, a key regulator of EMT.

133 ucose-regulated protein (GRP78/HSPA5), a key regulator of endoplasmic reticulum homeostasis and PI3K/

134 These data implicate aPKC as a novel regulator of energy and glucose homeostasis downstream o

135 and differential binding of HNF4alpha, a key regulator of expression of various fucosyltransferases.

136 Fibronectin (FN) is a critical regulator of extracellular matrix (ECM) remodeling throu

137 itamin D appears to be an important positive regulator of FGF23 production, particularly in uremia.

138 Our data suggest that SHP2 is an important regulator of fibroblast differentiation, and its loss as

139 frequently colocalized with MipZ, a negative regulator of FtsZ polymerization.

140 ecently established that in Arabidopsis, the regulator of G-protein signaling (RGS1) protein and a li

141 data implicate cAMP signaling as a critical regulator of genomic stability against platinum-induced

142 ATA motifs (+9.5) controls expression of the regulator of hematopoiesis GATA-2.

143 These data identify Dkk1 as a regulator of hematopoietic regeneration and demonstrate

144 The microenvironment is an important regulator of hematopoietic stem and progenitor cell (HSP

145 ermaphrodite-specific transcriptional master regulator of hermaphroditic cell identity tra-1, which r

146 Von Hippel Lindau protein (pVHL), a negative regulator of HIF, and that treatment with the c-src inhi

147 sults identify Sin3B as a novel and critical regulator of HSC functions.

148 for the aryl hydrocarbon receptor, a master regulator of IL-22 production.

149 (TC-PTP), also known as PTPN2, as a negative regulator of IL-7R-STAT signaling in T cell progenitors,

150 ary immune deficiency, PLCG2, and a negative regulator of inflammation, SLAMF8.

151 row cells and was implicated as a checkpoint regulator of inflammatory cytokines, as well as an infla

152 ethyltransferase SETDB1 as a novel, negative regulator of innate immunity.

153 putative novel function of tau protein as a regulator of insulin signaling in the brain.

154 that the PNN protein Brevican is a critical regulator of interneuron plasticity.

155 drolase Domain Containing 5 (ABHD5) is a key regulator of intracellular neutral lipids that has been

156 data indicate that PTP1BDelta6 is a positive regulator of JAK/STAT signaling in cHL.

157 the transcription factor EB (TFEB), a master regulator of lipid metabolism and lysosomal biogenesis a

158 Apolipoprotein C-III (apoC-III) is a key regulator of lipoprotein metabolism.

159 growth, survival, and migration and is a key regulator of lymphocyte trafficking.

160 The nervous system is emerging as a regulator of malignancy.

161 r, potently blocks CDK9, the transcriptional regulator of MCL-1.

162 on, suggesting that BCL11B was a stimulative regulator of MD transformation.

163 Interleukin-6 (IL-6) was identified as a regulator of mIndy by binding to its cognate receptor.

164 ription factor was identified as an upstream regulator of miR-194, consistent with a strong concordan

165 form the tuberous sclerosis complex (TSC), a regulator of mTOR activity.

166 Mechanistically, we identified TBK1 as a key regulator of mTORC1 activity in Trex1(-/-) cells.

167 nal regulators identified miR-495 as a novel regulator of multiple ARGs that have a role in modulatin

168 GTP is a major regulator of multiple cellular processes, but tools for

169 dentify SHP1 and SYK crosstalk as a critical regulator of MyD88 post-translational modifications and

170 udies demonstrate that HIF-2alpha is a novel regulator of neutrophil recruitment to colon tumors and

171 CXCR2 is an essential regulator of neutrophil recruitment to inflamed and dama

172 icting atypical protein kinase C, a negative regulator of non-muscle myosin IIB.

173 recognizes the beta-arrestin system as a key regulator of not only GPCRs, but also receptor tyrosine

174 is an agonist of PPAR-alpha and an important regulator of pain and innate immunity.

175 GBM cells, and that Nrdp1 acts as a negative regulator of PCP signaling by inhibiting Dvl through a n

176 o indirectly modulate amyloid pathology as a regulator of peripheral inflammation.

177 and macroorchidism, and the role of IGSF1 as regulator of pituitary hormone secretion.

178 his work identifies a PH domain protein as a regulator of plant metal transporter localization, provi

179 d modifier (SUMO) and comprises an important regulator of protein function.

180 main-containing protein (p66Shc) is a master regulator of reactive oxygen species (ROS).

181 re due to the activation of NRF2, the master regulator of redox stress tolerance.

182 indicate that LARP4 is a posttranscriptional regulator of ribosomal protein production in mammalian c

183 our data demonstrate that IL-27 is a potent regulator of ROS induction and may be a novel therapeuti

184 c transport complexes and identifies a novel regulator of slow transport.

185 that the transcription co-factor CRP2 was a regulator of smooth muscle gene expression.

186 Although Csk is known as a negative regulator of Src kinases, the effects of Csk on Gliotact

187 ating that alpha7beta1 can act as a negative regulator of STAT3 activity.

188 nfluenced by oxygen supply, an environmental regulator of stem cell activity.

189 lifecycle, implying that iRhom2 is a primary regulator of stimulated cytokine and growth factor signa

190 We identify zyxin as a regulator of stress fibre mechanics, as stress fibres ar

191 Notch is a critical regulator of T cell differentiation and is activated thr

192 Expression of CD200 (OX2), a negative regulator of T-cell function that binds CD200 receptor (

193 protein-1 (AP-1) factor JunB is an essential regulator of Th17 cell identity.

194 nger transcription factor EGR1 as a negative regulator of the beige fat program.

195 TOR is a master regulator of the cell's growth and metabolic state, and

196 Recently, it was found that Vps4, the key regulator of the cellular ESCRT machinery, is necessary

197 Properdin (FP) is an essential positive regulator of the complement alternative pathway (AP) pro

198 Our results reveal SMURF2 as an important regulator of the critical communication between osteobla

199 MAP kinase phosphatase (MKP) DUSP2, a known regulator of the ERK and p38 MAPKs, is unique amongst th

200 ation of glutamate decarboxylase 1 (GAD1), a regulator of the GABA neurotransmitter metabolic pathway

201 zation and identifies Kapbeta2 as a critical regulator of the Hh pathway and a potential drug target

202 ddition, we identified Rab27 as an important regulator of the intracellular LFA-1 translocation.

203 Pyruvate dehydrogenase (PDH) is the main regulator of the Krebs cycle and is located upstream of

204 GSK3beta is an established regulator of the Notch signaling pathway, although its m

205 we have found here that loss of PDHK4, a key regulator of the pyruvate dehydrogenase complex, caused

206 hich encodes p120 RasGAP (RASA1), a negative regulator of the Ras small GTP-binding protein.

207 knockdown of the expression of NSF, the key regulator of the SNARE system, significantly affected in

208 It is a negative regulator of tissue repair and regeneration in multiple

209 that CLIP170 serves as an intrinsic negative regulator of TLR4 signaling that targets TIRAP.

210 hlight the importance of RALY as an indirect regulator of transcription and cell cycle progression th

211 r Sr0161 targets identified the mRNA for the regulator of type III secretion system.

212 ing protein for RAGA, and GATOR2, a positive regulator of unknown molecular function.

213 with the role of CCN1 as a negative feedback regulator of vascular endothelial growth factor (VEGF) r

214 ed positively with levels of miR156, a major regulator of VPC in plants, and corresponding changes in

215 Our results unveil HDAC3 as a regulator of WAT physiology, which acts as a molecular b

216 iple experiments, we manipulated apterous, a regulator of wing development.

217 R-spondin1 is a secreted regulator of WNT signaling, involved in both embryonic d

218 fferential activity of positive and negative regulators of alternative polyadenylation.

219 with components of the early spliceosome and regulators of alternative splicing.

220 he spectrum of target RNAs includes positive regulators of apoptosis and inflammation, and modulators

221 ostatin-1 could thus be considered as potent regulators of BBB permeability and inflammation that inf

222 e specific for Ras or Rap, and are important regulators of cellular signaling.

223 Several key regulators of ciliogenesis and ciliary signaling are mut

224 n signaling in addition to their function as regulators of CP and actin.

225 DELAY OF GERMINATION 1 (DOG1) are essential regulators of dormancy.

226 Additional work to uncover -cis and -trans regulators of EIF2B5 splicing identified several factors

227 (miRNAs) are important post-transcriptional regulators of gene expression and are implicated in the

228 schizonts specifically upregulate additional regulators of gene expression, including other AP2 trans

229 d GlnK), which orchestrate interactions with regulators of gene expression, transport proteins, and m

230 ith key roles in islet physiology, including regulators of glucose sensing and hormone secretion, are

231 survival of DTPs is, in part, maintained by regulators of H3K9me3-mediated heterochromatin formation

232 To identify novel secreted regulators of HSC maturation, we performed RNA sequencin

233 Circulating cytokines and growth factors are regulators of inflammation and have been implicated in a

234 Receptor tyrosine kinases (RTK) are major regulators of key biological processes, including cell g

235 HDACs are known to be powerful negative regulators of memory formation, but it is not clear whet

236 recently emerged as key post-transcriptional regulators of mitochondrial gene expression.

237 es, we show that IRF4 and MAFB were critical regulators of monocyte differentiation into mo-DCs and m

238 that these transcription factors are master regulators of neuropsychiatric function.

239 tion factors, histone-modifying enzymes, and regulators of nucleosome positioning.

240 a are now increasingly appreciated as active regulators of numerous physiological processes initially

241 sed screen of the kinome to identify genetic regulators of PGRN levels in a rodent cell-based model s

242 MiT transcription factor family are pivotal regulators of several lineage-selective differentiation

243 show that anaerobic microsites are important regulators of soil carbon persistence, shifting microbia

244 Wnts are known regulators of synapse formation, and our data reveal tha

245 These results position MAP4Ks as important regulators of the DLK/JNK signaling pathway.SIGNIFICANCE

246 reviously reported that AAK1 and GAK, kinase regulators of the host adaptor proteins AP1 and AP2, are

247 MicroRNAs have recently emerged as important regulators of the innate immune system.

248 signaling in darkness by targeting positive regulators of the light response, mainly transcription f

249 consistent markers of treatment response and regulators of the MAPK/Wnt systems.

250 , oncogenic mutations in NRAS/KRAS, upstream regulators of the RAF/MEK/ERK pathway, have been reporte

251 rine, have intriguingly emerged as potential regulators of the receptor trafficking in addition to th

252 ate membrane domains that partition upstream regulators of the TORC1 and TORC2 signaling pathways to

253 sh BiP and its J domain co-chaperones as key regulators of the UPR.

254 nternalization property that clears negative regulators of the WNT-receptor complex from the membrane

255 as spurred efforts to develop pharmaceutical regulators of their activity.

256 SEQUENCE 7 (FRS7) and FRS12, act as negative regulators of these processes.

257 in gene expression, often mediated by global regulators of transcription.

258 MicroRNAs are key regulators of vascular smooth muscle cells (VSMCs) pheno

259 Such wHTH proteins are important regulators of virulence gene transcription in many patho

260 that modulates the transcription of upstream regulators of WNT and MAPK-ERK signaling to safeguard na

261 functions that describe interactions between regulators on downstream genes and proteins.

262 the human dynein complex by three prominent regulators on dynamic microtubules in the presence of en

263 These splicing regulators play key roles in insulin release and beta ce

264 have also been shown to bind the complement regulator protein factor H.

265 Mena(INV), an isoform of the motility regulator protein Mena, contributes to prometastatic phe

266 port how it modulates the interaction of the regulator protein TubY.

267 ctivation of two murine post-transcriptional regulators, Pumilio 1 (Pum1) and Pum2, severely reduced

268 with tissue-specific deletion of the mTORC1 regulator Raptor in alpha cells (alphaRaptorKO), we show

269 metry revealed that the primary ciliogenesis regulator, RILPL1 specifically interacts with the LRRK2-

270 Mutations in the Retinitis Pigmentosa GTPase Regulator (RPGR) cause retinal dystrophy, but how this a

271 We demonstrate that the transcriptional regulator Runx1 is essential for the generation of ROR-g

272 ory differentiation; however, the epigenetic regulator(s) underpinning this process remains unknown.

273 ns reveal that the plasma membrane cell fate regulator, SCRAMBLED (SCM), is mislocalized in ugt80B1 m

274 vel TetR-family transcriptional zinc-sensing regulator SczA.

275 and activation of a key ISG transcriptional regulator, signal transducer and activator of transcript

276 up to 161 genes that encode transcriptional regulators, some of unknown function in CD8(+) T cells,

277 rotein NT-NtrC, and the sporulation response regulator Spo0F.

278 The oxidative stress regulator Spx is ubiquitously found among Gram-positive

279 been characterized by changes in epigenetic regulators such as the lysine demethylase KDM4.

280 Further, regulator target gene lists frequently are not curated o

281 l be of general use in contextually refining regulator target genes for discoveries across many conte

282 Rather than being dominant-negative regulators, Tcf1 short isoforms are adequate in supporti

283 1 (mTORC1) protein kinase is a master growth regulator that becomes activated at the lysosome in resp

284 mTOR complex I (mTORC1) is a central growth regulator that senses amino acids through a pathway that

285 found that LFY and AP1 are conserved floral regulators that act nonredundantly in C. hirsuta, such t

286 is signaling pathway and key transcriptional regulators that direct AM-specific gene expression have

287 It is now evident that many orphan regulators that lack cognate kinases do not rely on phos

288 , we identified the Tudor-interacting repair regulator (TIRR) that specifically associates with the i

289 FMRP and possibly other post-transcriptional regulators to regulate neurogenesis.

290 in transferring signals from transcriptional regulators to RNA polymerase II in eukaryotes.

291 s would advance the ability of companies and regulators to select alternatives to harmful ingredients

292 tional approach for identification of master regulator transcription factor in a genome.

293 This 'master regulator' transcription factor is at the top of the hie

294 n-enhancer of activated B cells and negative regulators tumor necrosis factor-alpha-induced protein 3

295 DNA promoter methylation of cyclin D1 regulators were assessed and correlated with clinicopath

296 -growth" model, a persistently acting growth regulator whose distribution is pre-patterned by the not

297 ghlight a pivotal link between an epigenetic regulator, WHSC1, and key intracellular signaling molecu

298 d feed-forward loops that link developmental regulators with biosynthetic genes.

299 FMRP is both an RNA- and channel-binding regulator, with critical roles in neural circuit formati

300 The transcription regulator YAP controls organ size by regulating cell gro