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1 dition of the in vivo modulator protein RGS (regulator of G protein signaling).
2 rotein family of neuronal RGS, is a critical regulator of G protein signaling.
3 ng of receptors to G protein or to the Sst2p regulator of G protein signaling.
4 one of which contains Rgs2, which encodes a regulator of G protein signaling.
7 d RANKL-induced signaling proteins and found regulator of G-protein signaling 10 (RGS10) is predomina
8 ur group demonstrated that mice deficient in Regulator of G-protein Signaling 10 (RGS10), a microglia
10 eins (C5a receptor; G-beta-2; G-alpha,i-2,3; regulator of G-protein signaling-10; G-protein coupled r
11 or expressed on myeloid cells 1 (TREM1), and regulator of G-protein signaling 13 (RGS13) were increas
15 netic protein receptor type II (BMPRII), and regulator of G-protein signaling 14 (RGS14) increased Gc
17 identified as an interacting protein of the regulator of G protein signaling 16 (RGS16) providing a
24 ral product extracts for those that increase regulator of G protein signaling 2 (RGS2) protein levels
31 st partially explained by the enhanced RGS2 (regulator of G-protein signaling 2) activity resulting f
32 thermore, myostatin stimulated expression of regulator of G-protein signaling 2, a GTPase-activating
39 ivation leads to a sustained localization of regulator of G protein signaling 4 (RGS4) at the plasma
41 logenesis and observed a robust induction of regulator of G protein signaling 4 (RGS4) mRNA expressio
43 erived NO, which triggers the degradation of regulator of G protein signaling 4 (RGS4) to activate th
48 ology, suggested that SPL is able to recruit regulator of G-protein signaling 4 (RGS4) to the M3R sig
49 assembling a complex between the A1R and the regulator of G-protein signaling 4 (RGS4), a protein kno
50 ation and postmortem studies have implicated regulator of G-protein signaling 4 (RGS4), which negativ
51 Here, during an MS study of the PTMs of the regulator of G-protein signaling 4, we discovered that t
52 sion profiling revealed a marked loss of the regulator of G protein signaling 5 (RGS5) mRNA in transg
53 regulator of procontractile GPCR signaling, regulator of G protein signaling 5 (RGS5), in unprovoked
54 trast, beta-agonists decreased expression of regulator of G protein signaling 5 (RGS5), which is an i
55 response to Ag by CD4(+)CD44(+) T cells via regulator of G protein signaling 5- and IL-6-dependent p
61 eta5) can form complexes with members of the regulator of G protein signaling 7 (RGS7) family, but it
63 o isoforms of the GTPase-activating protein, regulator of G protein signaling 9 (RGS9), control such
64 hering for its efficient inactivation by the regulator of G-protein signaling 9 GTPase-activating pro
66 ceptor-specific signaling protein, RGS9 (for regulator of G-protein signaling 9), plays an essential
71 together by adding hydroxylamine and/or the regulator of G-protein signaling-9 catalytic domain (RGS
72 but robustly with a crg1 mutant that lacks a regulator of G protein signaling and is hyperresponsive
74 n of the genes Rgs13 and Rgs16, which encode regulators of G-protein signaling, and results in suppre
75 ins, including Galpha subunits, Ric-8, AGS3, regulators of G-protein signalings, and scaffolding prot
76 everal RGS proteins that can act as negative regulators of G protein signaling are expressed in the h
82 e involved in thymopoiesis, we expressed the regulator of G protein signaling domain of p115RhoGEF to
83 in-containing protein kinase (RCK1), a novel regulator of G protein signaling domain-containing prote
86 ably mediated by a GRK2 N-terminal RGS-like (regulator of G-protein signaling) domain interaction wit
87 ember of a subfamily of RhoGEFs that contain regulator of G protein signaling domains, is partially l
88 gene, galectin-9, myxovirus protein A (MxA), regulator of G-protein signaling, endothelial and smooth
90 s constitutive complexes with members of the regulator of G protein signaling family of proteins to m
92 in-containing phosphatase-1 (SHP-1), and the regulator of G-protein signaling family member, RGS18.
94 the complex between the ninth member of the regulators of G protein signaling family (RGS9-1) and it
95 in vivo in opposition to RGS2, another RGS (regulator of G protein signaling) family member known to
96 Recently we found that proteins of the RGS (regulator of G protein signaling) family suppress PI3K a
100 velopment of the kidney vasculature and RGS (regulator of G-protein signaling) genes, suggesting a po
101 PRG, LARG, and p115 share the presence of a regulator of G protein signaling homology (RGS) domain.
102 ombinase) and overexpression of GRK2 and its regulator of G protein signaling homology (RH) domain (G
103 e nucleotide exchange factors that contain a regulator of G protein signaling homology (RH) domain.
105 the large lobe of the kinase domain and the regulator of G protein signaling homology domain (RHD) i
106 exchange factor p115RhoGEF, which contains a regulator of G-protein signaling homology domain (RH) in
107 cognized functionally important sites in the regulator of G-protein signaling homology domain of GRK5
109 show how the three domains of GRK2-the RGS (regulator of G protein signaling) homology, protein kina
110 ulated phosphorylation of Ser-539 in Sst2, a regulator of G protein signaling in yeast Saccharomyces
111 G alpha(12/13)-specific inhibitor, p115RGS (regulator of G protein signaling), in combination with 2
113 lpha12/13 subunits are known to activate the regulator of G-protein signaling-like family of guanine
114 RG is a multidomain protein composed of PDZ, regulators of G-protein signaling-like (RGSL), Dbl-homol
115 in subunits G alpha i and G alpha o, and the regulator of G protein signaling Loco are required in th
117 tein signaling) family, RGS9-2 is a critical regulator of G protein signaling pathways that control l
118 ng proteins that buffer either Galpha(q/11) (regulator of G protein signaling protein 3T and carboxyl
120 ty by the complex of the ninth member of the regulator of G protein signaling protein family (RGS9) w
122 GPA1 is regulated by Gbetagamma and the RGS (regulator of G protein signaling) protein AtRGS1, which
123 nd Ggamma subunits and their regulatory RGS (Regulator of G-protein Signaling) protein are conserved
125 al membrane glycoprotein that interacts with regulator of G protein signaling proteins and shares sig
130 R or GoLoco domain-containing proteins, RGS (regulator of G protein signaling) proteins, and accessor
134 Rho GEF (guanine nucleotide exchange factor) regulator of G protein signaling (rgRGS) domains of p115
136 as sorting nexin 13) is a member of both the regulator of G protein signaling (RGS) and sorting nexin
137 ck-in mice with point mutations that disrupt regulator of G protein signaling (RGS) binding to Galpha
138 ing Galpha(o) itself and two subunits of the regulator of G protein signaling (RGS) complex that inhi
140 ma subunit dimer (Gbetagamma) and the Gbeta5/regulator of G protein signaling (RGS) dimer play fundam
141 rough RhoGEFs that contain an amino-terminal regulator of G protein signaling (RGS) domain (RGS-RhoGE
142 de exchange factors (rhoGEFs) that contain a regulator of G protein signaling (RGS) domain (RGS-rhoGE
144 ion of the G protein alphas subunit with the regulator of G protein signaling (RGS) domain of axin.
145 epsilon was inhibited by coexpression of the regulator of G protein signaling (RGS) domain of p115Rho
146 oGEF contains a PSD-95/Dlg/ZO-1 domain and a regulator of G protein signaling (RGS) domain upstream o
148 smooth muscle that contain a binding domain [regulator of G protein signaling (RGS) domain] capable o
151 we provide new evidence that the pleiotropic regulator of G protein signaling (RGS) family member RGS
156 of PPARdelta also induces the expression of regulator of G protein signaling (RGS) genes, which are
157 s an effector-like interaction with the GRK2 regulator of G protein signaling (RGS) homology domain t
158 consists of intimately associated kinase and regulator of G protein signaling (RGS) homology domains.
159 Here, we identified RGS13, a member of the Regulator of G protein Signaling (RGS) protein family, a
160 G protein alpha subunit with a member of the regulator of G protein signaling (RGS) protein family.
161 agment of GRK2 previously characterized as a regulator of G protein signaling (RGS) protein for Galph
162 Light-triggered recruitment of a truncated regulator of G protein signaling (RGS) protein or a Gbet
166 ay as a model, we evaluated the ability of a regulator of G protein signaling (RGS) protein to suppre
167 nit odr-3 or loss of eat-16, which encodes a regulator of G protein signaling (RGS) protein, restores
168 e complex between the photoreceptor-specific regulator of G protein signaling (RGS) protein, RGS9-1,
171 tion of G protein signaling is attenuated by regulator of G protein signaling (RGS) proteins acting a
182 t with a panel of Ggamma subunits as well as regulator of G protein signaling (RGS) proteins that con
183 n a number of signaling molecules, including Regulator of G protein Signaling (RGS) proteins, and has
184 ation of posttranslational modification of 2 regulator of G protein signaling (RGS) proteins, RGS10 a
186 receptor (GPCR) signaling are shaped by the regulator of G protein signaling (RGS) proteins, which p
191 We show that septins colocalize with the regulator of G protein signaling (RGS) Sst2, a GTPase-ac
193 2 correlated with high ex vivo expression of regulator of G protein signaling (RGS), RGS13 and RGS16,
195 t depalmitoylate proteins, and we studied R7 regulator of G protein signaling (RGS)-binding protein (
196 nucleotide exchange factors (GEFs) 1 and 2, regulator of G protein signaling (RGS)-homology-RhoGEFs
199 and PDZ domain proteins, contains two tandem regulator of G-protein signaling (RGS) domains for which
200 tiation through its interaction with Loco, a regulator of G-protein signaling (RGS) protein and a kno
201 erating G-protein deactivation kinetics, the regulator of G-protein signaling (RGS) protein family mo
218 overlap with the site on G alpha(q) bound by regulator of G-protein signaling (RGS) proteins, which f
222 genomic knock in of a mutation that disables regulator of G-protein signaling (RGS)-Galpha(i2) intera
228 electively enhanced by genetic disruption of regulators of G protein signaling (RGS) activity at G(al
241 5 uniquely forms heterodimers with R7 family regulators of G protein signaling (RGS) proteins (RGS6,
253 pled receptors (GPCRs), we hypothesized that regulators of G protein signaling (RGS) proteins may be
254 e G protein beta subunit that dimerizes with regulators of G protein signaling (RGS) proteins of the
256 coupled receptors is crucially controlled by regulators of G protein signaling (RGS) proteins that sh
258 effectors, beta(5) associates with R7 family regulators of G protein signaling (RGS) proteins when pu
261 Acceleration of Galpha GTPase activity by regulators of G protein signaling (RGS) was demonstrated
262 G) b-wave is absent, and the R7 subfamily of regulators of G protein signaling (RGS), which includes
265 quantitative polymerase chain reaction, and regulators of G protein-signaling (RGS) 4 function in kn
266 ince their discovery more than 20 years ago, regulators of G protein-signaling (RGS) proteins have re
269 gative forms of these alpha subunits or with regulators of G-protein signaling (RGS) constructs.
270 leading to upregulation of the expression of regulators of G-protein signaling (Rgs) genes that facil
275 G protein alpha subunits and their attendant regulators of G-protein signaling (RGS) proteins control
277 Here we provide the first evidence that regulators of G-protein signaling (RGS) proteins serve t
278 s required for DBC function and recruits the regulators of G-protein signaling (RGS) proteins, RGS7 a
280 d positive transcripts for G(o) interactors: regulators of G-protein signaling (RGS), Ret-RGS1 (a var
287 ecently established that in Arabidopsis, the regulator of G-protein signaling (RGS1) protein and a li
288 Coexpression of beta-arrestins 1 and 2, regulators of G-protein signaling RGS2 or RGS4, the RhoA
290 catalyzed by a protein complex that includes regulator of G-protein signaling RGS9-1 and the G-protei
291 ncing the interaction between alphat and its regulator of G protein signaling (RGS9), which is consti
292 protein-coupled receptor kinases (GRKs) and Regulators of G protein signaling (RGSs), deactivation e
294 act with and stabilize the R7 members of the regulators of G-protein signaling (RGSs): RGS6, RGS7, RG
295 ty and gene expression required the negative regulator of G protein signaling Sst2 and partially requ
296 mice with cardiac-specific overexpression of regulator of G-protein signaling subtype 4 (RGS4), a GTP
297 naling (RGS) protein subfamily are versatile regulators of G-protein signaling throughout the nervous
299 iatal glutamatergic synapses, by suppressing regulator of G protein signaling type 4 (RGS4) activity,
300 ophy by promoting proteasomal degradation of regulator of G protein signaling type 4 (RGS4), thus rel
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