ライフサイエンスコーパス: regulatory enzyme

1 ATHIONINE gamma-SYNTHASE (AtCGS), Met's main regulatory enzyme.

2 the molecular architecture of this important regulatory enzyme.

3 of structure-function relationships of this regulatory enzyme.

4 ct binding of a kinesin-related protein to a regulatory enzyme.

5 nit interactions, resulting in an allosteric regulatory enzyme.

6 biopterin (BH4) is a cofactor of a number of regulatory enzymes.

7 operties and effector sensitivities of these regulatory enzymes.

8 y functional human E2 that mediated enhanced regulatory enzyme activities but, lacking E3BP, supporte

9 '-AMP, is a potent activator of an important regulatory enzyme, AMP-activated protein kinase (AMPK).

10 that HDAC3 represses the synthesis of a key regulatory enzyme and reveal a novel mechanism by which

11 tion and cooperative properties of bacterial regulatory enzymes and hemoglobin.

12 ssociated with hyperlipidemia, altered lipid regulatory enzymes and receptors, and increased risk of

13 his issue, we examined the expression of S1P regulatory enzymes and S1P receptors during cardiac deve

14 sed to describe the allosteric properties of regulatory enzymes and subsequently extended to receptor

15 Renal expression of vitamin D regulatory enzymes and vitamin D receptor was higher in

16 e self-association and activity of important regulatory enzymes, and examined conformational properti

17 Other critical regulatory enzymes are also associated with NCX1, includ

18 e macromolecular complex suggests that these regulatory enzymes are coordinately positioned to regula

19 The functions of regulatory enzymes are essential to modulating cellular

20 The activities of both regulatory enzymes are regulated in vivo as described in

21 ,4-trisphosphate 5/6-kinase (ITPK1) is a key regulatory enzyme at the branch point for the synthesis

22 moserine dehydrogenase (HSD) function as key regulatory enzymes at branch points in the aspartate ami

23 encodes a member of the Pak family of actin-regulatory enzymes, but whose in vivo function is unknow

24 ulations of MASS models explicitly show that regulatory enzymes can control dynamic states of network

25 dvances in our understanding of how PTMs and regulatory enzymes control the signaling activity of RLR

26 suggest the EGAP NAT complex is an essential regulatory enzyme controlling the function of a subset o

27 we demonstrate that prostaglandin E2 and its regulatory enzyme, COX-2, are also targets of Tpl2-trans

28 nthesis by increasing phosphorylation of the regulatory enzyme CTP:phosphocholine cytidylyltransferas

29 ectively inhibiting the activity of the rate-regulatory enzyme, CTP:phosphocholine cytdylyltransferas

30 -Brucella interactions, we utilized c-di-GMP regulatory enzyme deletion mutants.

31 is frequently considered vested in classical regulatory enzymes, each strongly displaced from equilib

32 Protein kinases constitute a large family of regulatory enzymes, each with a distinct specificity to

33 hat S. mutans ADP-Glc PPase is an allosteric regulatory enzyme exhibiting sensitivity to modulation b

34 ine cytidylyltransferase (Pcyt2) is the main regulatory enzyme for de novo biosynthesis of phosphatid

35 he expression of ent-kaurene synthase, a key regulatory enzyme for gibberellin synthesis, the followi

36 ee-fold increase in the activity of the rate-regulatory enzyme for PC synthesis, cytidylyltransferase

37 '-phosphate hydrolase has been proposed as a regulatory enzyme for vitamin B-6, but we found B-6 vita

38 l histidine kinases (HKs) are quintessential regulatory enzymes found ubiquitously in bacteria.

39 r structural principles operate in bacterial regulatory enzymes, gene repressors (and the related nuc

40 il now the identity or the function of these regulatory enzymes has not been defined in any crop plan

41 At reduced activities, the classic regulatory enzymes, hexokinase and glycogen phosphorylas

42 atory T cells and was mediated by the immune-regulatory enzyme IDO and TGF-beta.

43 ndritic cells (DCs) competent to express the regulatory enzyme IDO in mice are a small but distinctiv

44 inactivate GS kinase-3beta (GSK-3beta), the regulatory enzyme immediately upstream of GS, by serine

45 de strong evidence that NCED is indeed a key regulatory enzyme in ABA biosynthesis in leaves, and dem

46 Although it has never been reported as a regulatory enzyme in any system studied to date, kinetic

47 ene determining the activity of an important regulatory enzyme in catecholamine inactivation is assoc

48 of phosphoglucomutase 1 (PGM), an important regulatory enzyme in cellular glucose utilization and en

49 antothenate kinase 2 (PANK2) is an essential regulatory enzyme in coenzyme A biosynthesis.

50 ivates acetyl-CoA carboxylase (ACC), the key regulatory enzyme in fatty acid biosynthesis, in the arc

51 er fructose-1,6-bisphosphatase (FBPase) is a regulatory enzyme in gluconeogenesis that is elevated by

52 a PSTK for M. xanthus PFK (Mx-PFK), the key regulatory enzyme in glycolysis.

53 ession of fatty acid synthase (FAS), the key regulatory enzyme in lipid biosynthesis.

54 The key regulatory enzyme in melatonin synthesis is arylalkylami

55 Glycine N-methyltransferase (GNMT) is a key regulatory enzyme in methyl group metabolism.

56 oding putrescine N-methyl transferase, a key regulatory enzyme in nicotine formation.

57 cceptor) oxidoreductase, EC 1.7.99.5), a key regulatory enzyme in one-carbon metabolism, results in a

58 idermal ornithine decarboxylase (ODC), a key regulatory enzyme in polyamine biosynthesis, may suppres

59 cose (Glc) pyrophosphorylase (AGPase), a key regulatory enzyme in starch biosynthesis, is highly regu

60 -glucose pyrophosphorylase (AGPase) is a key regulatory enzyme in starch biosynthesis.

61 ADP-glucose pyrophosphorylase is a key regulatory enzyme in starch synthesis in most plant tiss

62 Ornithine decarboxylase is a key regulatory enzyme in the biosynthesis of polyamines, and

63 ADP-Glc pyrophosphorylase (PPase), a key regulatory enzyme in the biosynthetic pathway of starch

64 Pantothenate kinase (PanK) is the key regulatory enzyme in the CoA biosynthetic pathway in bac

65 Pantothenate kinase (PanK) is the key regulatory enzyme in the CoA biosynthetic pathway.

66 Pantothenate kinase (PanK) is a key regulatory enzyme in the coenzyme A (CoA) biosynthetic p

67 latter group as purF, which encodes the key regulatory enzyme in the de novo purine synthetic pathwa

68 ic acid (ACC) synthase which is an important regulatory enzyme in the ethylene biosynthetic pathway.

69 Chalcone synthase, a key regulatory enzyme in the flavonoid pathway, constitutes

70 The key regulatory enzyme in the gluconeogenesis pathway, fructo

71 a polypeptide revealed its identity as a key regulatory enzyme in the glycolytic pathway, namely phos

72 endent isocitrate dehydrogenase (IDH), a key regulatory enzyme in the Krebs cycle, is a multi-tetrame

73 ansferase (AANAT) is the penultimate and key regulatory enzyme in the melatonin biosynthetic pathway.

74 e to acetyl-CoA in mitochondria and is a key regulatory enzyme in the metabolism of glucose to acetyl

75 rnesyl pyrophosphate synthase (hFPPS), a key regulatory enzyme in the mevalonate pathway, catalyzes t

76 tors of IkappaB kinase-beta (IKKbeta), a key regulatory enzyme in the nuclear factor-kappaB (NF-kappa

77 CPT-Ialpha is a key regulatory enzyme in the oxidation of fatty acids in the

78 e to acetyl-CoA in mitochondria and is a key regulatory enzyme in the oxidation of glucose to acetyl-

79 Heme oxygenase-1 (HO-1) is the chief regulatory enzyme in the oxidative degradation of heme t

80 Glucokinase (GCK) is a key regulatory enzyme in the pancreatic beta-cell and cataly

81 lutaryl coenzyme A (HMG-CoA) synthase, a key regulatory enzyme in the pathway for endogenous choleste

82 lutaryl-coenzyme A (HMG-CoA) synthase, a key regulatory enzyme in the pathway for endogenous choleste

83 din-endoperoxide synthase 2 (PTGS2) is a key regulatory enzyme in the synthesis of the antifibrotic a

84 (PDE) of retinal photoreceptors is a central regulatory enzyme in the visual transduction pathway of

85 bifunctional substrate preference of the key regulatory enzyme in tocopherol (vitamin E) biosynthesis

86 the trafficking and life span of a critical regulatory enzyme in vivo.

87 Three key regulatory enzymes in ganglioside biosynthesis, sialyltr

88 stinct compartmentalization of PP2A and PP2A regulatory enzymes in plasma membrane microdomains and i

89 Two key regulatory enzymes in the bile acid biosynthesis pathway

90 use the total amount of one of the principle regulatory enzymes in the extract (ACP, the enzyme compl

91 minant negative and dominant active forms of regulatory enzymes in the Ras/MAPK and PKB pathways and

92 apeutic potential of inhibiting two critical regulatory enzymes in this pathway-kynurenine-3-monooxyg

93 nfection stimulated expression of the immune regulatory enzyme indoleamine 2,3 dioxygenase (IDO) in l

94 is uniquely competent to express the T-cell regulatory enzyme indoleamine 2,3-dioxygenase (IDO) in m

95 brain, AKAP79/150 incorporates PKA and other regulatory enzymes into signal transduction networks tha

96 Acid ceramidase (AC) is a key regulatory enzyme involved in ceramide metabolism, and m

97 Stearoyl-CoA desaturase (SCD) is a regulatory enzyme involved in the synthesis of the monou

98 alterations in protein expression levels of regulatory enzymes involved in glucose and choline metab

99 erations in the protein expression levels of regulatory enzymes involved in lipid metabolism, includi

100 A fundamental issue in allosteric regulatory enzymes is the identification of pathways of

101 e previously shown declining activity of the regulatory enzyme lactosylceramide N-acetylglucosaminylt

102 affinity of receptors or in the activity of regulatory enzymes may alter the susceptibility of certa

103 -glucose pyrophosphorylase (AGPase) is a key regulatory enzyme of bacterial glycogen and plant starch

104 clopropane-1-carboxylic acid synthase, a key regulatory enzyme of ethylene biosynthesis) and LeIAA (A

105 encoding acetyl-CoA carboxylase-alpha, a key regulatory enzyme of fatty acid synthesis, is transcribe

106 /fructose-2,6-bisphosphatase is an important regulatory enzyme of glucose metabolism.

107 Phosphorylase kinase, a regulatory enzyme of glycogenolysis in skeletal muscle,

108 As a regulatory enzyme of glycolysis, inducible 6-phosphofruc

109 m of 6-phosphofructo-2-kinase (iPFK2), a key regulatory enzyme of glycolysis.

110 of JH acid methyltransferase (jhamt), a key regulatory enzyme of JH biosynthesis.

111 oadenylate phosphodiesterase (2'-PDE), a key regulatory enzyme of the interferon pathway.

112 oadenylate phosphodiesterase (2'-PDE), a key regulatory enzyme of the interferon pathway.

113 ose-5-phosphate synthase (DXS), an important regulatory enzyme of the mevalonate-independent pathway

114 onine decarboxylase (AdoMetDC) is a critical regulatory enzyme of the polyamine biosynthetic pathway

115 eved by AMP, an allosteric activator of this regulatory enzyme of the tricarboxylic acid cycle.

116 In the yeast Saccharomyces cerevisiae, key regulatory enzymes of gluconeogenesis such as fructose-1

117 (PCK1) and glucose-6-phosphatase (G6PC), key regulatory enzymes of hepatic gluconeogenesis.

118 nd neutral sphingomyelinase (NSMase) are key regulatory enzymes of sphingolipid metabolism, promoting

119 oA reductase and acetyl-CoA carboxylase (key regulatory enzymes of sterol synthesis and fatty acid sy

120 rylation was attributed to inhibition of the regulatory enzyme pyruvate dehydrogenase.

121 expression of the myofibrils and the calcium-regulatory enzyme SERCA2, and reduced the magnitude and

122 y showed that androgen induces the first and regulatory enzyme spermidine/spermine N1-acetyltransfera

123 es, which phosphorylate and thereby activate regulatory enzymes such as phospholipase C-gamma 1 and p

124 are reflected in the fractional states of a regulatory enzyme, such as the fraction of the total enz

125 rofiling to identify candidate substrates of regulatory enzymes, such as kinases and ubiquitin ligase

126 nsferase (plsB) of Escherichia coli is a key regulatory enzyme that catalyzes the first committed ste

127 Pantothenate kinase (PanK) is a regulatory enzyme that controls coenzyme A (CoA) biosynt

128 on in catechol-O-methyltransferase (COMT), a regulatory enzyme that controls dopamine availability.

129 HMG1 is a key regulatory enzyme that controls the amounts of isoprenoi

130 RNase E is a key regulatory enzyme that controls the principal pathway fo

131 RNase E is an important regulatory enzyme that governs the principal pathway for

132 merous functional aspects of a key metabolic regulatory enzyme that is important for high-titer viral

133 RNase E is an important regulatory enzyme that plays a key role in RNA processin

134 cible 6-phosphofructo-2-kinase, a glycolysis-regulatory enzyme that protects against diet-induced int

135 tosolic phospholipase A(2) (cPLA(2)alpha), a regulatory enzyme that releases arachidonic acid (AA) fo

136 ndoleamine 2,3-dioxygenase 1 (IDO1) is a key regulatory enzyme that supports Treg function and periph

137 The regulatory enzymes that act to sustain centromeric cohes

138 Phosphatases are regulatory enzymes that antagonize the action of kinases

139 ansferase subunit is a member of a family of regulatory enzymes that are known to control a range of

140 Among the many regulatory enzymes that contribute to these processes is

141 is a complex process involving a variety of regulatory enzymes that control the intracellular respon

142 ons along with the transcription factors and regulatory enzymes that have been previously identified

143 Hexokinase, the first regulatory enzyme to initiate glycolysis by converting g

144 increased by 40%) and the involvement of key regulatory enzymes, using isolated working rat hearts ex

145 hanism of tissue-specific expression of this regulatory enzyme, we characterized the major (type 2) C

146 1%; beta-HAD, 32%) and glycolytic (PFK, 18%) regulatory enzymes were also increased in mVEGF-/- mice.

147 redoxin reductases (TRs) are important redox regulatory enzymes, which control the redox state of thi

148 Cyclin-dependent kinases (Cdks) are regulatory enzymes with temporal and spatial selectivity

149 mic, effector-modified interactions of these regulatory enzymes with the flexibly held outer domains

150 choline cytidylyltransferase (CCT), the rate-regulatory enzyme within the CDP-choline pathway, by 40%

151 taneous measurement of the activation of key regulatory enzymes within single cells.