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1 horylation dependent binding of a proteasome regulatory factor.
2 tes maturation through secondary postmitotic regulatory factors.
3 y which Dbp5 and mRNA export is modulated by regulatory factors.
4 culating hormones, neural signals, and local regulatory factors.
5 is was an indirect effect through additional regulatory factors.
6 highly dose-sensitive in its use of crucial regulatory factors.
7 itates binding and recruitment of additional regulatory factors.
8 ources of data to improve predictions for AS regulatory factors.
9 enzymes, architectural proteins, and immune regulatory factors.
10 k data, to characterize the cooperativity of regulatory factors.
11 iled understanding of relevant developmental regulatory factors.
12 I interferon (IFN) signaling and interferon regulatory factor 1 (IRF-1) expression is required to en
14 nt-associated swelling.IMPORTANCE Interferon regulatory factor 1 (IRF-1) is a transcription factor th
17 ransient nature in the absence of interferon-regulatory factor 1 (IRF-1), a transcription factor with
18 uble-stranded RNA, depends on the interferon regulatory factor 1 (IRF1) and IRF2 transcription factor
19 cells are defective in inducible interferon regulatory factor 1 (IRF1) expression by occluding RelA
22 caffolding protein sodium-hydrogen exchanger regulatory factor 1 (NHERF1) interacts with the calcium
23 ctors of 53BP1, including replication timing regulatory factor 1 (RIF1) and Pax transactivation domai
24 irus 8 (HHV-8) gene product viral interferon regulatory factor 1 (vIRF-1) is targeted to mDRM during
27 dietary antigen was dependent on interferon regulatory factor 1 and dissociated from suppression of
28 -->induction of cAMP-->downregulation of IFN regulatory factor 1 expression and binding to the p28 IF
29 and macrophage recruitment (e.g., interferon regulatory factor 1, CD97), adaptive immune response (in
31 on was STAT3-dependent and we identified IFN regulatory factor-1 (IRF1) as the STAT3-inducible mediat
32 induced nuclear translocation of interferon-regulatory factor-1 (IRF1) in hepatocytes in vivo, and C
37 on factor C3 (RFC3), FAM111A, and interferon regulatory factor 2 (IRF2)-were confirmed by custom assa
38 ion of the transcription cofactor interferon regulatory factor 2-binding protein 2 (IRF2BP2), and gen
39 erferon genes-TANK-binding kinase-interferon regulatory factor 3 (cGAS-STING-TBK1-IRF3) signaling pat
40 ear factor kappaB (NF-kappaB) and interferon regulatory factor 3 (IRF-3) at a step subsequent to thei
41 ear factor kappaB (NF-kappaB) and interferon regulatory factor 3 (IRF-3), classically inducing IFNbet
42 We show that influenza B virus induces IFN regulatory factor 3 (IRF3) activation and IFN-lambda1 ge
43 )-dependent signaling pathway leading to IFN regulatory factor 3 (IRF3) activation and induction of I
47 l infection by degradation of the interferon regulatory factor 3 (IRF3) has been subject of conflicti
48 viral signaling protein (MAVS) or interferon regulatory factor 3 (IRF3) in the IFN induction pathways
50 rmed that these miRNAs potentiate interferon regulatory factor 3 (IRF3) phosphorylation and transloca
53 orylates the transcription factor interferon regulatory factor 3 (IRF3) to promote interferon express
54 capable of blocking activation of interferon regulatory factor 3 (IRF3) via the retinoic acid inducib
55 expression and phosphorylation of interferon-regulatory factor 3 (IRF3) was decreased in EML-TA cells
57 in this study show that cFLIPL inhibits IFN regulatory factor 3 (IRF3), a transcription factor centr
58 nding kinase 1 (TBK1) to activate interferon regulatory factor 3 (IRF3), resulting in production of t
59 e of inoculation independently of interferon regulatory factor 3 (IRF3)-, IRF7-, and IFNAR1-mediated
60 terferons (IFNs), despite maintenance of IFN regulatory factor 3 (IRF3)-dependent IFN-stimulated gene
66 romoter when it was stimulated by interferon regulatory factor 3 (IRF3)/5D or its upstream molecules
67 and increases LPS-induced NF-kappaB and IFN regulatory factor 3 activation and IL-10 secretion, indi
68 factors was increased, including interferon regulatory factor 3 and 7 (IRF-3 and IRF-7) and STAT-1,
69 increased baseline expression of interferon regulatory factor 3 and 7 mRNAs and production of distin
71 e activation of the transcription factor IFN regulatory factor 3 and the molecule UNC93B1, indicating
72 , and mice with disruption of the interferon regulatory factor 3 gene (Irf3(-/-)), with or without di
73 ction, type I IFN signaling by STING and IFN regulatory factor 3 is detrimental to the host during F.
74 to a self-Ag, DC-intrinsic expression of IFN regulatory factor 3 is required to induce optimal prolif
75 ain-containing adapter inducing IFN-beta-IFN regulatory factor 3 pathway is required for Ezrin-defici
76 gregation, and TANK-binding kinase 1 and IFN regulatory factor 3 phosphorylation in inflammasome-defi
78 serine/threonine kinase 1)-IRF3 (interferon regulatory factor 3) signaling cascade leading to IFN-be
81 dited knockout human cells, we show that IFN regulatory factor 3-mediated IFN induction and downstrea
85 (HSV)-infected cells and initiate interferon regulatory factor-3 signaling, but it has been unclear h
86 works of transcription factors involving IFN regulatory factor 4 (IRF4) and IRF8, and are specialized
89 production, lung histopathology, interferon regulatory factor 4 (IRF4) mRNA expression, and nuclear
90 roducts, the transcription factor interferon regulatory factor 4 (IRF4) promotes regulatory T cell (T
94 and reduced protein expression of interferon regulatory factor 4 and B-cell lymphoma 6 (BCL6) in huma
95 molecule inhibition downregulate interferon regulatory factor 4 and MYC, and provides an explanation
96 hermore, expansion of both Th2-promoting IFN regulatory factor 4(+) programmed death ligand 2(+) dend
97 omide are associated with reduced interferon regulatory factor 4, a downstream target of cereblon.
99 rentiation is associated with defects in IFN regulatory factor 4, B cell-activating transcription fac
100 reg cells used the transcription factor, IFN regulatory factor 4, to dampen harmful Th2 cell response
101 es CCL17 production by acting through an IFN regulatory factor 4-dependent (IRF4-dependent) pathway i
102 und to be driven by 2 variants of interferon regulatory factor 4-dependent dermal type 2 conventional
112 have shown that the transcription factor IFN regulatory factor 5 (IRF5) polarizes macrophages toward
113 ted LMP1 expression, we find that interferon regulatory factor 5 (IRF5), a direct target of p53, is a
114 tivity controls the activation of interferon regulatory factor 5 (IRF5), a transcription factor impli
115 inhibited both TLR7/8- and TLR9-induced IFN regulatory factor 5 and NF-kB p65 nuclear translocation.
117 a 5 bp CGGGG length polymorphism in the IFN regulatory factor 5 gene (IRF5) was genotyped by PCR.
119 or-alpha, the chemokine CCL2, and interferon regulatory factor-5 (IRF5), a marker of inflammatory mac
121 tions and common polymorphisms in interferon regulatory factor 6 ( IRF6) are associated with both syn
123 ' risk allele increased transcription of the regulatory factor 6 (RFX6) gene, increased homeobox B13
125 pression by hMPV was dependent on interferon regulatory factor 7 (IRF-7) expression but not on IRF-3
126 ignaling leading to NF-kappaB and interferon regulatory factor 7 (IRF7) activation has not been inves
127 mains of TRIF and RIP1 to disrupt interferon regulatory factor 7 (IRF7) activity, a critical type I I
128 ers showed increased basal expression of IFN regulatory factor 7 (IRF7) and IFN-beta, as well as incr
129 rve that RelA inducibly binds the native IFN regulatory factor 7 (IRF7) promoter in an ATM-dependent
130 ral immunity by downregulation of interferon regulatory factor 7 (IRF7), an immune factor with a pivo
131 e downstream transcription factor interferon regulatory factor 7 (IRF7), and type I interferons (IFN-
132 , IL-33 downregulated viperin and interferon regulatory factor 7 gene expression and rapidly degraded
135 The transcription factor IRF7 (interferon regulatory factor 7) is a key regulator of type I interf
136 ession of antiviral host factors (interferon regulatory factor 7, CXCL10 [gamma interferon-inducible
137 encodes the transcription factor interferon regulatory factor 7, in an otherwise healthy child who s
138 masome by reducing the mRNA stability of IFN regulatory factor 7, which regulated AIM2 transcription.
140 The transcription factor (TF) interferon regulatory factor 8 (IRF8) controls both developmental a
142 The homozygous K108E mutation of interferon regulatory factor 8 (IRF8) is reported to cause dendriti
144 ffect of the transcription factor interferon regulatory factor 8 (IRF8), which is highly expressed in
145 the IFN-gamma response and repressed the IFN regulatory factor 8-regulated network that controls cent
147 In vitro, increased expression of interferon regulatory factor-9 and IRG1 and itaconic acid treatment
149 1 is not an miR93 target but that interferon regulatory factor-9, which can regulate IRG1 expression,
150 cted to examine the role of miR93-interferon regulatory factor-9-immunoresponsive gene-1 (IRG1)-itaco
151 togenes is mainly controlled by the positive regulatory factor A (PrfA), a member of the Crp/Fnr fami
152 se brain, including reduced levels of myelin regulatory factor and myelin basic protein, and decrease
154 clusters are enriched in binding of specific regulatory factors and are therefore defined as 'Regulat
156 , there is relatively little known about the regulatory factors and mechanisms that govern the spread
157 elective recruitment of cis-proline-specific regulatory factors and region-specific modulation of the
158 sured along with markers of RNA polymerase I regulatory factors and regulators of protein synthesis.
159 in our understanding of the transcriptional regulatory factors and signaling networks that serve to
160 emonstrated that TRIM29 inhibited interferon-regulatory factors and signaling via the transcription f
161 vironmental stimuli and a complex network of regulatory factors are known to modulate expression of V
163 tations in IRF8, which encodes an interferon regulatory factor, as a cause of familial NK cell defici
166 d populations of these states changed as the regulatory factors complexin and Munc13 were added.
167 propose that the Mcl-1L/S balance is a novel regulatory factor controlling the mitochondrial fusion a
168 n cord versus peripheral blood and to define regulatory factors controlling this proliferation, we co
169 cture and DNA modifications [i.e., chromatin regulatory factors (CRF)] and genes encoding histone pro
170 tein 1 (ZBP1)/DNA-dependent activator of IFN-regulatory factors (DAI) that contain receptor-interacti
171 rect molecular interactions between multiple regulatory factors during neuronal differentiation in mi
172 as measurable ATPase activity alone, several regulatory factors (e.g., RNA, nucleoporin proteins, and
173 erentiation and altered expression of muscle regulatory factors, embryonic myogenesis and formation o
175 expression may be controlled by its internal regulatory factors, exclusively, or by external subsyste
176 Here, we demonstrate that EGFL6, a stem cell regulatory factor expressed in ovarian tumor cells and v
179 13B/Blys) and APRIL (TNFSF13) are important regulatory factors for lymphocyte activation and surviva
180 RC2, and TrxG complexes, which are essential regulatory factors for the maintenance of transcriptiona
181 s controlled by the combinatorial effects of regulatory factors from different biological subsystems
183 DNA-binding proteins, including the general regulatory factors (GRFs) Reb1p, Rap1p, and Abf1p, and P
184 ontain binding sites for one or more General Regulatory Factors (GRFs), most frequently Abf1 and Reb1
185 receptor (MOR) gene two decades ago, various regulatory factors have been shown to interact with the
186 still lack an integrated view of how all the regulatory factors identified interact or crosstalk to o
188 ur findings indicate that CK is an important regulatory factor in plant adaptation to arsenic stress.
189 icted by CENTIPEDE analysis to be bound by a regulatory factor in sperm were correlated with genomic
190 ion to a cytosolic AKAP-PKA interaction as a regulatory factor in the control of canonical Wnt signal
192 permidine revealed the interplay of multiple regulatory factors in B. burgdorferi gene expression.
193 ession and association of T-bet, GATA-3, and regulatory factors in CD8(+) T cells isolated from the b
194 me the roles of NuA4 KAT and other chromatin regulatory factors in controlling antisense transcriptio
195 ansformations occur upon removal of specific regulatory factors in many different cellular contexts,
196 ation for understanding the role of multiple regulatory factors in modulating Fshb gene activity.
197 the past few years upon removal of specific regulatory factors in organisms from Caenorhabditis eleg
199 tly improved the gene expression of myogenic regulatory factors in vitro, suggesting myogenic activat
201 m cells (ESCs) and are controlled by diverse regulatory factors, including pluripotent factors, epige
206 opmentally important genes, especially those regulatory factors involved in amphioxus development, an
209 tion of transcription factors NF-kappaB, IFN regulatory factor (IRF) 1, and IRF5 driving the expressi
211 week-old mice triply deficient in interferon regulatory factor (IRF) as a model, we show that blood-b
212 cyte inflammation, members of the interferon regulatory factor (IRF) family may also play a role in t
213 IRF4 is a unique member of the interferon regulatory factor (IRF) family playing critical regulato
214 tes excess c-di-AMP activates the interferon regulatory factor (IRF) pathway with enhanced levels of
216 ce (nonallergic) and identified CCL7 and IFN regulatory factor (IRF)-7 among the most upregulated mRN
218 anscription synergy of Il6 and Il12b via IFN regulatory factor (IRF)1 (TLR3-TIR domain-containing ada
219 ma cell-generating transcription factors IFN regulatory factor (IRF)4 and Blimp1, and paradoxically a
221 nthase (cGas), as well as the downstream IFN regulatory factors (IRF) 3 and 7 in type I IFN induction
222 e fusion protein of porcine interferon (IFN) regulatory factors (IRF) 7 and 3 [IRF7/3(5D)] strongly i
223 a fusion protein of porcine interferon (IFN) regulatory factors (IRF) 7 and 3 delivered by an adenovi
226 1 transcriptional repressors, the interferon regulatory factors IRF2 and IRF2BP2, which likely leads
227 ation of the transcription factor interferon regulatory factor (IRF4), which, along with the environm
228 ough host sensory pathways that activate IFN regulatory factors (IRFs) and nuclear factor kappaB.
229 dback loops mediated by inducible interferon regulatory factors (IRFs) and retinoic acid inducible ge
231 te that BAFF is a bona fide ISG and that IFN regulatory factors (IRFs) control the expression of BAFF
234 t three KSHV homologs of cellular interferon regulatory factors (IRFs), known as viral IRFs (vIRFs),
236 ress viral homologues to cellular interferon regulatory factors (IRFs), termed viral IRFs (vIRFs).
238 that the plasticity accommodated by certain regulatory factors is conserved, despite substantial cha
243 epetitive phosphorylation among central gene regulatory factors, may represent an important general p
245 ression thus indicating a role for different regulatory factors modulating expression of the gene.
253 f myelin genes that are downstream of myelin regulatory factor (MYRF or MRF), a transcriptional regul
255 HFE), fatty acid desaturase 2 (FADS2)/myelin regulatory factor (MYRF), transmembrane protease, serine
257 NHE3 directly binds Na(+)/H(+) exchanger regulatory factor (NHERF) family scaffolding proteins th
259 nd several scaffold proteins, including NHE3 regulatory factors (NHERFs), inositol trisphosphate (IP(
260 lt2, indicating that CmSlt2 was a downstream regulatory factor of CmNox1 and was involved in conidiat
261 datasets: mRNA expression and the associated regulatory factors of miRNA and lncRNA, and ALV gene exp
262 2 and DNA-dependent activator of interferon regulatory factor) opened a new paradigm: Nucleic acid s
264 1, MAGI-2, and MAGI-3], Na(+)/H(+) exchanger regulatory factor proteins (NHERFs) (NHERF1, NHERF2, PDZ
266 Pharmacological inhibition of chromatin co-regulatory factors represents a clinically validated str
268 The store-operated Ca(2+)entry-associated regulatory factor (SARAF) has recently been identified a
269 ed in silencing lines, suggesting that other regulatory factors should participate in pollen formatio
271 y step in NMD and occurs when SMG-1, its two regulatory factors SMG-8 and SMG-9, and UPF1 form a comp
272 ipt accumulation of important soybean embryo regulatory factors such as ABSCISIC ACID INSENSITIVE3 an
273 erts mucoprotective effects and that counter-regulatory factors such as dietary iron and luminal lipo
274 LIS1 concentration and the presence of other regulatory factors such as dynactin and may provide new
275 h vessel patterning might involve modulatory regulatory factors such as R-spondin 1 (Rspo1), an extra
276 se results indicate that posttranscriptional regulatory factors, such as microRNAs, influence the ass
277 n response to small changes in the levels of regulatory factors, such as the maternal Bicoid gradient
279 ephaly-1 (LIS1) is a highly conserved dynein-regulatory factor that binds directly to the dynein moto
280 tified hepatocyte nuclear factor 4alpha as a regulatory factor that bound endogenous CLDN7 promoter i
281 regulatory protein 2 (ESRP2) as a conserved regulatory factor that controls the neonatal-to-adult sw
283 ochondrial fission, Mff and Drp1 also act as regulatory factors that control mitochondrial fission an
288 s suggested that miR858a targets a number of regulatory factors that modulate the expression of downs
290 that allows for efficient activation of IFN regulatory factors to drive the antiviral transcriptome.
291 l's epigenome arises from interactions among regulatory factors-transcription factors and histone mod
294 cited by SBI-756, DNA damage, and cell-cycle regulatory factors were prominent, with mutations in mel
295 xpress in a coordinated fashion the myogenic regulatory factors, while down-regulating the satellite
298 y indicated posttranscriptional increases in regulatory factor X 5 mRNA and protein expression in OAD
300 egulated by the class II trans-activator and regulatory factor X, two transcription factors dedicated
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