ライフサイエンスコーパス: regulatory region

1 DNase I hypersensitive sites (i.e., putative regulatory regions).

2 nding sequence(s) (DBS) in the TSLP promoter regulatory region.

3 E-boxes within the Ppargamma transcriptional regulatory region.

4 s reduced the promoter activity of the MTHFR regulatory region.

5 noncoding DNA, which pinpointed a Cdkn2a cis-regulatory region.

6 e presence of a multitude of CBEs in the Scr regulatory region.

7 cally induced removal of the auto-inhibitory regulatory region.

8 t effect on pseudogene formation and loss of regulatory regions.

9 antly lower near 3' UTRs, the area rich with regulatory regions.

10 es in mutation rates in coding sequences and regulatory regions.

11 ons that form distinct recurrent patterns at regulatory regions.

12 n many cell types and detecting differential regulatory regions.

13 to test for the presence of transcriptional regulatory regions.

14 ys and reveals 5hmC localization in putative regulatory regions.

15 ns can be further utilized to discover novel regulatory regions.

16 RRs associate with functionally relevant cis-regulatory regions.

17 mic locus, including endogenous promoter and regulatory regions.

18 erence of advantageous heterozygosity at cis-regulatory regions.

19 egulations by discovering previously unknown regulatory regions.

20 fic variation on top of a shared core of CLL regulatory regions.

21 are controlled by specific motifs in compact regulatory regions.

22 DDLPS, with increased H3K9me3 at associated regulatory regions.

23 a useful model for functional studies of AD regulatory regions.

24 exome sequencing, and variants in non-coding regulatory regions.

25 t genes by decreasing STAT3 binding to their regulatory regions.

26 nal modifications that mostly occur at these regulatory regions.

27 alterations in developmental genes and their regulatory regions.

28 ethylation signatures characteristic of gene regulatory regions.

29 y annotations to identify point mutations in regulatory regions.

30 ding directly to the TA box in each of their regulatory regions.

31 on by altering the copy number of intergenic regulatory regions.

32 he genome, especially within genes and close regulatory regions.

33 ific DNA motifs, usually located at the gene regulatory regions.

34 we found that XAL2 is able to bind the TFL1 regulatory regions.

35 ine and 5-hydroxymethylcytosine at Bdnf gene regulatory regions.

36 c genes by binding to shared transcriptional regulatory regions.

37 modeling deacetylase (NuRD) complex to Pdcd1 regulatory regions.

38 sing H3K27me3 deposition at critical genomic regulatory regions.

39 the Isl1/Lhx3 pair initially engage distinct regulatory regions.

40 cinomas (PDAs) and identify commonly mutated regulatory regions.

41 l promoter regions, but vary in the upstream regulatory regions.

42 f rare naturally occurring mutations in gene-regulatory regions.

43 Ig heavy chain (IgH) expression, the IgH 3' regulatory region (3'RR) controls multiple transcription

44 e constant genes and is controlled by the 3' regulatory region (3'RR) in a stimulus-dependent manner.

45 The approximately 28-kb 3' regulatory region (3'RR), which is located at the most d

46 mputational tools fail to reliably determine regulatory region accessibility from the analysis of the

47 thioredoxin-binding domains and the central regulatory region actively primes MKK6, a key ASK1 subst

48 m one set of targets to another, controlling regulatory region activity and gene expression as cell d

49 urthermore, we have shown that the predicted regulatory region adjacent to rs11855415 acts as a bidir

50 t to understand how genetic variation in the regulatory regions affects gene expression.

51 dification, particularly methylation of gene regulatory regions, also acts to shape human brain funct

52 nt reflect the joint control of the negative regulatory region and activating phosphorylation.

53 binding to multiple enhancers in the Igh 3' regulatory region and Aicda locus, E-proteins regulated

54 induced AhR and MTA2 recruitment to the Stc2 regulatory region and induced Stc2 gene expression, whic

55 minantly (14 of 15 patients) in the negative regulatory region and Pro-Glu-Ser-Thr-rich domains, the

56 We show that AR binds to the miR-1-2 regulatory region and regulates miR-1 transcription.

57 ion of Lys-27 on histone H3 at the Tgf-beta1 regulatory region and thereby maintains epigenetic silen

58 s were determined by sequencing the upstream regulatory region and/or E6 region.

59 Regulatory regions and 7 coding exons of LOXL1 were dire

60 Mechanistically, E2A-PBX1 bound promoter regulatory regions and activated the transcription of it

61 the presence of Atoh1 binding sites in their regulatory regions and by analyzing Atoh1 ChIP-seq datas

62 te that MntR binds to both the mneP and mneS regulatory regions and directly activates transcription

63 yclopedia of DNA Elements (ENCODE)-annotated regulatory regions and had methylation profiles that med

64 ogether these data add multiple novel distal regulatory regions and pathways to the control of PD-1 e

65 of folding, fully extended fibers containing regulatory regions and promoters, and fibers condensed u

66 Given that most GWAS hits are in putative regulatory regions and transcript abundance is physiolog

67 te that EBNA1 binds directly to the promoter regulatory regions and upregulates the transcription of

68 on trans-activation through 5' conserved cis-regulatory regions and, in particular, whether the mamma

69 ch1) genes by directly binding to their gene regulatory regions, and eventually contributes to pathwa

70 for high-throughput screening of genes, gene regulatory regions, and long noncoding RNAs.

71 volutionary forces acting on genes and their regulatory regions, and provide a general resource for r

72 nregulation of synaptic plasticity genes and regulatory regions, and upregulation of immune response

73 atasets provide the most comprehensive human regulatory region annotation to date, and our approach a

74 ta resources include evidence-based gene and regulatory region annotation, genome variation and gene

75 genetic variation in many non-coding genomic regulatory regions are known to impart risk of colorecta

76 We show that regulatory regions are often shared between cell types o

77 We show that P-DMRs preferentially occur at regulatory regions, are characterized by intermediate le

78 Our results uncover a new critical regulatory region as a potential target for therapeutic

79 o the latency promoter and a known long-term regulatory region as important elements for vigorous tra

80 n by targeting TATA boxes in transcriptional regulatory regions as well as the poly adenine (poly (A)

81 hancer Emu with proximal 5' DH region and 3' regulatory regions as well as with Pax5-activated interg

82 t aberrantly methylated CpGs are enriched in regulatory regions associated with MYC protein motifs an

83 s located in their 5' regulatory region (the regulatory region-associated microsatellite, RRAM) that

84 al inactive ZF-TFs targeting within the same regulatory region bind as well as the most active ZF-TFs

85 Active enhancer chromatin structure at regulatory regions bound by the transcription factor hep

86 e significantly underrepresented in promoter regulatory regions but significantly overrepresented in

87 inding the TATA boxes in the transcriptional regulatory region, but it promotes higher levels of expr

88 repressor complex was absent from the CD133-regulatory region, but was present in the MCF-7 and prim

89 (MEF2D) binds and activates retina-specific regulatory regions by cooperative interaction with the t

90 Proteins that bind those regulatory regions can determine cell identity but have

91 n-induced DNA methylation status of CCR5 cis-regulatory regions (cis-regions).

92 regions, and CpG dinucleotides within the 5' regulatory regions, confirmed hypomethylation of all thr

93 e that elt-2 is controlled by three discrete regulatory regions conserved between C. elegans and C. b

94 tion in accessibility of progenitor gene cis-regulatory regions consistent with the reduction in thei

95 an N-terminal kinase domain and a C-terminal regulatory region consisting of a approximately 100-resi

96 domain, followed by a likely posttranslation regulatory region consisting of high serine and threonin

97 Both c-Maf and Cryaa regulatory regions contain arrays of AP-1 and Ets-bindin

98 These data demonstrate that many regulatory regions contain mutations under selective pre

99 n signals in the HLA-D region identified two regulatory regions containing 3562 polymorphisms that mo

100 A large downstream regulatory region contains a novel growth enhancer (GROW

101 The opvAB regulatory region contains four sites for OxyR binding (

102 Interestingly, the PD-1 transcriptional regulatory region continued to remain unmethylated in th

103 for the functional organisation of TFL1 cis-regulatory regions, contributing to our understanding of

104 Super-enhancers are an emerging subclass of regulatory regions controlling cell identity and disease

105 between transcription factors (TFs) and cis-regulatory regions (CRRs) characterized by nucleosome-de

106 making the positioning of nucleosomes within regulatory regions crucial to the regulation of gene exp

107 al analysis of five representatives of these regulatory regions demonstrated direct binding of OpaR i

108 The function of human regulatory regions depends exquisitely on their local ge

109 laria, the nucleosome positioning profile of regulatory regions deserves particular attention because

110 essibility at enhancers, promoters and other regulatory regions do not correlate with changes in nucl

111 s 5' end overlaps with the cis-acting distal regulatory region (DRR) of MyoD.

112 Computational analysis of regulatory regions from MEF2 isoform-dependent gene sets

113 hed GWAS catalogue, and mapped enrichment in regulatory regions from the ENCODE project.

114 and direct binding of pSmad1/5/8 to the Hcn4 regulatory region further confirm the Shox2-BMP genetic

115 mperature-dependent unfolding of Hsf1 in the regulatory region happening concomitant to tighter packi

116 Regulatory regions harbor multiple transcription factor

117 y, and for decades the proximal Il2 upstream regulatory region has served as a paradigm of tissue-spe

118 Genetic variants found in these regulatory regions have been shown to activate transcrip

119 posite DNA methylation patterns in the opvAB regulatory region: (i) in the OpvAB(OFF) state, GATC1 an

120 Motif analyses on these predicted regulatory regions identified 31 DNA motifs, including 5

121 -occupancy observed on PGC1beta and LPL gene regulatory regions identified.

122 uencing of the ventral dentate gyrus, a mood-regulatory region, identified metabolic factors as key m

123 Orthogonal genomics analysis of reprogrammed regulatory regions identifies individual drug-induced ep

124 sposons into the genome can disrupt genes or regulatory regions, impacting cellular function, so for

125 itional level of control is contributed by a regulatory region in the 5'-UTR of Runx2-P1.

126 says showed that AioR interacts with the mcp regulatory region in vivo and in vitro, and the precise

127 sm chromatin accessibility to identify novel regulatory regions in complex systems.

128 ularly evident in HTS assays for identifying regulatory regions in DNA (DNase-seq, ChIP-seq, FAIRE-se

129 ociated variants are preferentially found in regulatory regions in immune cells, particularly CD4(+)

130 eferential mapping of associated variants to regulatory regions in kidney but not extra-renal tissues

131 TF agnostic model for identifying functional regulatory regions in potentially any sequenced genome.

132 xperimental conditions, we predicted 217 RPG regulatory regions in the human genome.

133 used it to construct an intuitive summary of regulatory regions in the human genome.

134 We surveyed the Gdf5 locus for regulatory regions in transgenic mice and fine-mapped se

135 e enrichment of allergy SNPs falling in gene regulatory regions in various cells using Encode Roadmap

136 ediated in vivo exchange of epitope tags (or regulatory regions) in the ORF library strains, which fu

137 p3 gene expression are controlled by several regulatory regions including two enhancers in the conser

138 between the kinase domain and its N-terminal regulatory region independently of RAS activity.

139 AB proteins, also show widespread binding to regulatory regions, indicating that the human genome con

140 we provide evidence that variation at these regulatory regions is likely to also influence gene expr

141 We fine-mapped the regulatory region located in SMIM1 intron 2 in Swedish b

142 of the expansion segment 7 (ES7), a putative regulatory region located on the surface of the 60S ribo

143 g that efficient binding within one of these regulatory regions may be necessary but not sufficient f

144 We show that in solution the central regulatory region mediates a compact arrangement of the

145 they are not designed to identify individual regulatory regions mediating risk or the genes under the

146 AWNFR identified regulatory regions more effectively and accurately than

147 rized by rearrangements within the noncoding regulatory region (NCCR) and 1 point mutation, S267L in

148 e, and that mutations in melanocyte-specific regulatory regions near DDB1/TMEM138 correlate with expr

149 Consistent with gene expression changes, regulatory regions near genes involved in inflammatory r

150 Moreover, we identified a cis-regulatory region necessary for TFL1 expression in the v

151 ar domain (ICD3), and sequenced the negative regulatory region (NRR) and PEST (proline, glutamate, se

152 Unfolding of the extracellular negative regulatory region (NRR), enabling successive proteolysis

153 analysis revealed OpaR binding sites in the regulatory region of 55 carbon transporter and metabolis

154 ast, if PU.1 is bound at the transcriptional regulatory region of a gene during differentiation, PRC2

155 Here, we use the cis-regulatory region of an opposite target gene, ttx-3, to

156 Recent studies showed that the cis-regulatory region of Arabidopsis thaliana COPIA78/ONSEN

157 We characterize an interaction between the regulatory region of CFTR and calmodulin, the major calc

158 ssions, we identify a cis-regulatory module, Regulatory region of DUO1 (ROD1), which replicates the e

159 map to the coding region of sigH and in the regulatory region of kinA, encoding one the sensor kinas

160 indings that CTAR3 is a distinct functioning regulatory region of LMP1 and confirm that LMP1-induced

161 hich maps to the well-characterized negative regulatory region of MEK1.

162 transcription and encompassing the noncoding regulatory region of mtDNA in human and murine cells and

163 nal antibody (MAb) specific for the Negative Regulatory Region of Notch1 (NRR).

164 ide polymorphisms (SNPs) (rs12641001) in the regulatory region of SPP1 exhibited a statistically sign

165 Interestingly, the regulatory region of the 128 genes was overrepresented f

166 e determined that CarR directly binds to the regulatory region of the almEFG operon.

167 ate inhibits Tet-mediated demethylation of a regulatory region of the antimetastatic miRNA cluster mi

168 The GusR-specific DNA operator site in the regulatory region of the E. coli GUS operon is identifie

169 ters (PR1-1, PR1-2 and PR1-3) within the PR1 regulatory region of the Escherichia coli kps capsule ge

170 to interact with genomic elements within the regulatory region of the gene encoding the differentiati

171 Polymorphisms in the regulatory region of the human neuroplastin gene (NPTN)

172 detailed functional characterization of the regulatory region of the medaka fish Six3.2 ortholog and

173 ranscriptional co-factor FOG1 (ZFPM1) to the regulatory region of the mouse Gli1 gene, repressing the

174 dified by dimethylation at lysine 9 at a key regulatory region of the MyoD locus.

175 rease in the amount of open chromatin at the regulatory region of the p53 and p21 (Cdkn1a) genes.

176 the inhibition of EspR binding at the espACD regulatory region of the phoP mutant strain because of P

177 spontaneous sorghum mutant and suggested the regulatory region of the SbCAD2 can be a target site for

178 ow that ATF3 is bound to the transcriptional regulatory regions of >30% of differentially expressed g

179 Here, we demonstrate that SOX11 binds to regulatory regions of 2 important genes for microenviron

180 One method for identifying noncoding regulatory regions of a genome is to quantify rates of d

181 epressor IRF8, and impedes access of JunD to regulatory regions of alternative effector loci.

182 lerosis is complex and that variation in the regulatory regions of associated genes may be important

183 Regulatory regions of both tan and ebony failed to recap

184 is mediated through direct interactions with regulatory regions of cardiogenic genes, rather than reg

185 sal recruits the CBP/p300 coactivator to the regulatory regions of defined target genes in the presum

186 ifs of transcription factors in the upstream regulatory regions of differentially expressed lncRNAs,

187 sequence is overrepresented in the upstream regulatory regions of GA-induced and DELLA-repressed tra

188 s in methylation levels within promoters and regulatory regions of genes involved in TLR signaling in

189 asizing how the recent identification of cis-regulatory regions of genes within the eggshell patterni

190 Med15 can be independently recruited to the regulatory regions of heat shock factor 1 (Hsf1)-activat

191 chromatin landscape was also modified at the regulatory regions of HOXA10 and GATA1.

192 genomic variation, especially in non-coding regulatory regions of human genome.

193 lancing selection are enriched in active cis-regulatory regions of immune cells and epithelial cells,

194 role in mitosis; however, H3S10ph also marks regulatory regions of inducible genes in interphase mamm

195 aling and dissociated BRD4 from chromatin at regulatory regions of insulin receptor and EGFR family R

196 gulatory Build has been revamped to identify regulatory regions of interest and to efficiently highli

197 lincRNA-EPS localizes at regulatory regions of IRGs to control nucleosome positio

198 ition to shared target genes, Hoxa1 binds to regulatory regions of Nanog, and conversely Nanog binds

199 Together, they bind to regulatory regions of PAX3-FOXO1 target genes.

200 mary transcription factors recruiting SCC to regulatory regions of pluripotency genes and identify th

201 bstantial decrease in DNA methylation in the regulatory regions of pluripotency marker genes.

202 Using ncdDetect, we screened non-coding regulatory regions of protein-coding genes across a pan-

203 Hoxa1 also binds to regulatory regions of Sox2 (sex-determining region Y box

204 for directing CTCF to the promoter proximal regulatory regions of target genes across the genome, pa

205 by binding to TH response elements (TREs) in regulatory regions of target genes.

206 experiments revealed that T-bet can bind to regulatory regions of the CD38 gene.

207 cupancy of KDM4B and its target, H3K9me3, at regulatory regions of the Dlx3 locus.

208 e activities are then interpreted by the cis-regulatory regions of the genes involved in cell differe

209 -A, VEGF-C, FGFR3, and p57 by binding to the regulatory regions of the genes.

210 disorder, variation that affects non-coding regulatory regions of the genome is likely to play an im

211 ylated regions preferentially affected known regulatory regions of the genome, specifically overlappi

212 -deficient mouse tissues, that KLF3 occupies regulatory regions of the Lgals3 gene, and that KLF3 dir

213 reduces chromatin accessibility in multiple regulatory regions of the MEF2C-activated genes.

214 s, we further detected PBX1 binding to known regulatory regions of the neuron-specific genes Dcx and

215 e identify and functionally characterize the regulatory regions of the P. falciparum gene PF3D7_12347

216 ers in Pparg and Ucp1 genes, and of putative regulatory regions of the Ppara gene.

217 shared by the predicted distal and proximal regulatory regions of the same RPGs, a likely general me

218 2A and may be involved in its recruitment to regulatory regions of the Sox2 gene.

219 We also tested mutations in the coding and regulatory regions of the virus, and chimeric haemagglut

220 The regulatory regions of these genes are potential candidat

221 occupancy of the Rad4-Rad23 complex from the regulatory regions of these genes, enabling their induct

222 terns of histone acetylation at the proximal regulatory regions of these genes.

223 to the RAG1 promoter as well as directly to regulatory regions of transcription factors previously i

224 The bacterial gene regulatory regions often demonstrate distinctly organize

225 k loci of genome-wide significance at likely regulatory regions on chromosomes 13q22.1 (rs11841589, n

226 ding increase in cytosine methylation at key regulatory regions on the viral and host genomes.

227 of aggregating motifs defined by gene exons, regulatory regions, or genome-wide sliding windows.

228 new mechanistic and functional insights into regulatory region organization in the nucleus.

229 In addition to the analysis of known regulatory regions, our web tool is useful for the analy

230 Notably, VDR occupancy of the PPARgamma regulatory region precludes PPARgamma occupancy of this

231 h chromatin unpacking in the WRKY6 and PDF12 regulatory regions, primed WRKY6 expression, unprimed PD

232 We propose a model in which the central regulatory region promotes ASK1 activity via its pleckst

233 Identification of all human genes and their regulatory regions provides the essential framework for

234 predict activity of evolutionarily divergent regulatory regions, providing insights into spatial rela

235 Epigenetic landscapes in the regulatory regions reflect binding condition of transcri

236 not fall within gene coding regions, but in regulatory regions, rendering their interpretation diffi

237 nalysing and predicting the evolution of cis-regulatory regions requires an understanding of their po

238 Analysis of Foxc1 regulatory regions revealed a conserved recognition elem

239 The crystal structure of the central regulatory region reveals an unusually compact tetratric

240 ments, we adapt the self-transcribing active regulatory region sequencing (STARR-seq) strategy, a hig

241 tion sequencing and self-transcribing active regulatory region sequencing of enhancer profiles reveal

242 By adapting self-transcribing active regulatory region sequencing, we evaluated the effect of

243 essed proteins contain within their proximal regulatory regions sites that are bound by SOX6 accordin

244 ells, indicating that condition-specific RPG regulatory regions still need to be discovered and inves

245 Regulatory regions such as promoter CpG islands, CpG sho

246 Variations in DNA methylation, especially in regulatory regions such as promoters and enhancers, are

247 ide-resolution dissection of transcriptional regulatory regions, such as enhancers, but only few regi

248 looping-mediated association with the IgH 3' regulatory region super-enhancer and leads to decreased

249 range DNA interactions and regulating IgH 3' regulatory region super-enhancer function.

250 In parallel, we performed global mapping of regulatory regions, termed enhancers, to gain mechanisti

251 ting of a 105-nucleotide insertion in the qk regulatory region that decreases qk transcription but do

252 ions between genetic variants within the cis-regulatory region that influence gene expression after a

253 methyltransferase domain, a large N-terminal regulatory region that is composed of an RFTS (replicati

254 redoxin-binding domain, along with a central regulatory region that links the two.

255 nslated region (UTR) of mRNAs is the primary regulatory region that mediates post-transcriptional con

256 parse in genes, reflecting the clustering of regulatory regions that act at short and long-range, whi

257 regions for the presence of transcriptional regulatory regions that are active in a specific cell ty

258 anscriptional start sites and other putative regulatory regions that are differentially accessible in

259 Our findings of transcribed uncharacterized regulatory regions that contain CRSs support their RNA-m

260 sites in ASXL1 mutated MF cases are found in regulatory regions that could be associated with aberran

261 P-seq enables genome-scale identification of regulatory regions that govern gene expression.

262 within coding regions, ignoring those within regulatory regions that may contribute to gene expressio

263 nscription factors (TFs), the noncoding gene regulatory regions that they bind to, and the genes whos

264 Many of these regions exhibit hallmarks of regulatory regions that were active earlier in neuronal

265 hic microsatellite locus located in their 5' regulatory region (the regulatory region-associated micr

266 ain is highly conserved, the function of the regulatory regions (the N terminus and the low-complexit

267 TFL1 expression is based on distinct cis-regulatory regions, the most important being located 3'

268 l enrichment of disease risk alleles on gene regulatory regions, they are not designed to identify in

269 hich preferentially integrate near genes and regulatory regions; thus, insertional mutagenesis is a s

270 million nucleotides spanning 15,000 putative regulatory regions tiled at 5-nucleotide resolution in t

271 ce that EtrB directly interacts with the ler regulatory region to activate LEE expression and promote

272 ative information on the contribution of cis-regulatory regions to gene expression.

273 Linking such regulatory regions to gene promoters in disease-relevant

274 kinase S6K1 and Polycomb proteins at genomic regulatory regions to repress expression of anti-adipoge

275 It contains information about regulatory regions, transcription factor binding sites,

276 is linked to several characteristics such as regulatory region type, motif sequence degeneracy, DNase

277 dR bound to the promoter DNA of rpoS and the regulatory region upstream of bosR via AT-rich TAAAATAT

278 R affinity at least 40-fold for the extended regulatory regions upstream of the liaFSR and liaXYZ ope

279 s (TSS) to termination sites and two contain regulatory regions upstream of TSS.

280 The HLA-DPB1 regulatory region variant rs9277534 is associated with H

281 tion within the 2,800-bp E5a-E5b-L1-upstream regulatory region was initially studied in 181/207 (87.4

282 ed that GATA1s binding at specific erythroid regulatory regions was impaired, while binding at many n

283 Global hypomethylation of gene-regulatory regions was observed during tumor progression

284 are, highly sequence-conserved, IEC-specific regulatory regions, we discovered an ancient enhancer up

285 The NFATc1/STAT regulatory regions were found to interact with the promo

286 han 86.6% of these computationally predicted regulatory regions were partially corroborated by indepe

287 bind at RAREs in the Hoxa1 and Cyp26a1 gene regulatory regions, whereas only HDAC1 binds at the RARb

288 parted from standard practice by identifying regulatory regions which replicate across samples and co

289 nd upregulation of immune response genes and regulatory regions, which are targeted by factors that b

290 roach we were able to identify two novel cis-regulatory regions, which direct Eya1 expression to the

291 of highly expressed genes as well as distal regulatory regions with enhanced activity.

292 MEF2C binds active regulatory regions with high-chromatin accessibility in

293 ethods for WGBS are mainly designed for gene regulatory regions with multiple under-methylated CpGs (

294 2.2 x 10(-7)), and were mostly in introns or regulatory regions with predicted effects including prot

295 lements, cis- regulatory module, in the CLV3-regulatory region, with different affinities and conform

296 ibitor, identifying a potentially targetable regulatory region within p27.

297 cleotide polymorphisms (SNPs) are located in regulatory regions within introns or in regions between

298 and histone methylation marks identified DNA regulatory regions within the Cd44, Cdkn1a, and Cdkn2b g

299 ies through STAT3, whose binding to putative regulatory regions within the MIR29 gene is enriched by

300 o and in vitro analyses demonstrate that the regulatory regions within these two promoters contain th