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1 gion, suggesting that this region may play a regulatory role.
2 L27 is not only essential but possibly has a regulatory role.
3 th FOXK2 and FOXO3 where both factors play a regulatory role.
4 ng of T cells in vivo, indicating a critical regulatory role.
5 ell polarity pathways, suggesting a possible regulatory role.
6 ervous system (SNS), wherein CB1 plays a key regulatory role.
7 ly unstable, and in this capacity it plays a regulatory role.
8 ibility to apoptosis underscored its central regulatory role.
9 ighted for an especially early and important regulatory role.
10 orementioned modifications seem to play some regulatory roles.
11 roteasome inhibition and thus may have other regulatory roles.
12 ns for which lipids have both structural and regulatory roles.
13 side in noncoding regions of the genome with regulatory roles.
14 e at core promoters, while Tail and CKM play regulatory roles.
15 nt cytoskeletal proteins with structural and regulatory roles.
16 RNAs and RNA-binding proteins with potential regulatory roles.
17 ssembling tRNA fragments and emphasize their regulatory roles.
18 rom OCs with different lifetimes likely play regulatory roles.
19 essed pseudogenes into mRNAs or lncRNAs with regulatory roles.
20 opmental stages to execute a wide variety of regulatory roles at virtually every step of gene express
25 proinflammatory, may normally play an immune-regulatory role by maintaining a state of relative TLR t
26 Nucleosomes play important structural and regulatory roles by tightly wrapping the DNA that consti
27 me, where they play specific mechanistic and regulatory roles, constituting a "code within the code"
31 w that different muscle fibres have distinct regulatory roles during regeneration in the planarian Sc
32 ion between NusA and NusG could play various regulatory roles during transcription, including recruit
33 tentially harmful consequences, although its regulatory role encompasses other classes of transcripts
35 Modeling studies have predicted a critical regulatory role for A-type potassium (KA) channels towar
40 l remote sensing, and indicates an important regulatory role for carotenoid pigments in evergreen pho
42 However, whether integrins still maintain a regulatory role for cell traction generation and cell lo
46 s had reduced TGFbeta signaling, revealing a regulatory role for embryonic myosin in the TGFbeta sign
47 decreased NK cell cytotoxicity, indicating a regulatory role for IFN-gamma in the pathogenesis of vir
48 L33-ILC2-IL5-neutrophil axis defines a novel regulatory role for ILC2 in acute lung injury that could
49 on, our findings reveal a previously unknown regulatory role for LRRK2 in CX3CR1 signalling and sugge
50 the variant rs1474868 to a platelet-specific regulatory role for MFN2 and demonstrates the utility of
51 and of virus-infected cells, evidence for a regulatory role for NK cells has been emerging in differ
52 ever, some studies have suggested a positive regulatory role for NLRX1 in inducing antiviral response
53 These empirical results suggest a plausible regulatory role for NnCYP76B6 in CPT biosynthesis and al
55 wo enzymes into peroxisomes suggests a novel regulatory role for peroxisomes under various stress con
57 induced by AF-TUSC2-erlotinib, indicating a regulatory role for ROS in the efficacy of the three dru
59 enin expression suggested the existence of a regulatory role for SOX9 targeting the WNT canonical pat
62 Taken together, our studies support a key regulatory role for the fractalkine axis in advanced and
63 In this study we investigated a potential regulatory role for the Hox5 gene family, Hoxa5, Hoxb5,
64 Notch4-ICD regulation, suggesting a negative regulatory role for the PI3K-AKT pathway in Notch4 nucle
66 lour patterns, thus demonstrating a positive regulatory role for this gene in eyespot determination.
67 se of eotaxin-1 levels, suggesting a complex regulatory role for this haplotype in the general popula
69 lpha-ketoglutarate levels demonstrates a key regulatory role for this metabolite in telomeric silenci
74 chanisms of dynein-MT interactions, identify regulatory roles for AAA3, and help define the interplay
75 revealed additional B12-binding enzymes and regulatory roles for B12 Here we report the development
76 ebrafish CHARGE model thus reveals important regulatory roles for Chd7 at multiple points of neural c
81 However, the identification and putative regulatory roles for serine and threonine phosphorylatio
82 Recent experimental studies revealed complex regulatory roles for several microribonucleic acids and
84 Cell, Graf el al. and Chu et al. uncover new regulatory roles for TERRA at the telomere and at distan
89 at the histone chaperone OsNAPL6 may serve a regulatory role in abiotic stress physiology possibly vi
92 In conclusion, YY1 may play an important regulatory role in ATP6V1A expression with potential mec
93 sts these neurons may play an integrative or regulatory role in bilaterally coordinated behaviors in
94 myosin binding protein C (cMyBP-C) has a key regulatory role in cardiac contraction, but the mechanis
95 sphotransferase protein IIA(Glc) plays a key regulatory role in catabolite repression in addition to
96 dynamics of chromatin likely play a critical regulatory role in cellular function, it is critical to
97 ', is an RNA transcript that plays a pivotal regulatory role in cellular processes, including the cel
98 ndicating that E-cadherin plays an important regulatory role in CLDN1/OCLN localization on the cell s
99 arily conserved enzyme also plays a negative regulatory role in controlling de novo membrane phosphol
100 rs and mutants, provided insights into their regulatory role in defined modules of the JA network.
101 We find that integrins exert a significant regulatory role in determining the magnitude and spatial
105 , it is not clear whether ECRs play a direct regulatory role in G-protein signaling or simply serve a
106 se findings imply that PKD1 plays a critical regulatory role in GBS-induced proinflammatory reactions
108 icited phosphorylation of TIS11b plays a key regulatory role in its mRNA decay-promoting function.
110 tudy demonstrates that PRC2 has an important regulatory role in lineage-committed tissue cells by sup
111 ntified an lncRNA that can play an important regulatory role in liver function and provide new insigh
112 e proteotoxic stress and thus play a central regulatory role in maintaining protein homeostasis.
115 nriched for Celf1 binding sites supporting a regulatory role in mRNA stability of these transcripts.
116 lude that nucleoporins play an unanticipated regulatory role in NEBD, by recruiting PLK-1 to the NE t
118 d that MKK7-JNK signaling plays an important regulatory role in neural development, however, post-dev
119 dence suggests that lncRNAs play an integral regulatory role in numerous functions, including determi
120 e two distinct endodermal barriers and their regulatory role in nutrient transport is still limited.
123 n of IL-36Ra and that neutrophils can play a regulatory role in psoriatic inflammation with regard to
124 th loss of desmoglein-1 expression and has a regulatory role in repairing epithelial changes induced
125 s.A growing number of 'pseudoenzymes' with a regulatory role in signal transduction processes but wit
129 allowed the conclusion that proteins play a regulatory role in TGRs extension and, consequently, mod
130 eurotransmitter release, respectively, and a regulatory role in the adaptation-dependent availability
134 s suggest the Sts proteins play an important regulatory role in the host response to bacterial infect
135 utaryl coenzyme A reductase (HMGR) has a key regulatory role in the mevalonate pathway for isoprenoid
137 gene deletion mutant, indicating its global regulatory role in the oxidative stress response of F. t
138 e histone binding of DPF2 plays an important regulatory role in the transcriptional program that driv
140 little is known about which proteins have a regulatory role in these cells and how these cells can b
141 Plant microRNAs (miRNAs) play important regulatory roles in a number of developmental processes.
144 R demonstrate the adipokine exerts important regulatory roles in APC growth, survival, migration and
148 plays important but still poorly understood regulatory roles in eukaryotic cells, including as a sig
149 a current view of the enteric glia and their regulatory roles in gastrointestinal (GI) (patho)physiol
151 mbers of the IL-1 family play protective and regulatory roles in immune defense against the opportuni
155 ic splicing profiles, and may play important regulatory roles in modulating mRNA degradation or trans
157 ion of 5'TOP mRNAs are controversial and its regulatory roles in mTORC1-mediated translation remain u
158 end to cluster in the vicinity of genes with regulatory roles in multicellular development and differ
159 discovered in animals and plants, and their regulatory roles in numerous biological processes have b
160 cteria express many small RNAs for which the regulatory roles in pathogenesis have remained poorly un
162 RNAs may exert critical post-transcriptional regulatory roles in regulating pathological neovasculari
164 is identified the miRNAs that play important regulatory roles in response to low salinity stress, pro
167 rotein arginine methyltransferases exert key regulatory roles in T cell activation and differentiatio
169 two signaling molecules that have important regulatory roles in the development and plasticity of ne
172 s evidence for better understanding of miRNA regulatory roles in the process of fiber development, wh
173 sponsive to P depletion, suggesting putative regulatory roles in the regulation of P homeostasis.
175 actors AtWRKY15 and AtWRKY40 have repressive regulatory roles in this touch-responsive gene expressio
176 transcription factor that plays multiple key regulatory roles in transcription elongation, terminatio
177 s transcriptomes, which could play important regulatory roles in translation and other biological pro
178 ells, MADS-box genes are known to play major regulatory roles in various biological processes by comb
182 rent muscle types have distinct and specific regulatory roles in wound signalling and patterning to e
183 generally not thought to play a significant regulatory role, in fact impart restrictions on the deve
184 ity level of a node may not be linked to its regulatory role mean that, failing to scale the data pri
185 estigation has thus underscored the negative regulatory role of Ac2PIM-TLR2 signaling on NOD2 pathway
186 f holo-ACPP in the cell identify a potential regulatory role of ACPS in fatty acid biosynthesis.
189 gs demonstrate for the first time the direct regulatory role of cancer associated a2-isoform V-ATPase
190 ltogether, these data highlight the critical regulatory role of CFTR in integrin activation by chemoa
191 m or saliva is of great interest, due to the regulatory role of cortisol within various physiological
193 facilitating action on evoked release, and a regulatory role of Cplx3/4 in the adaptation-dependent a
194 aches reveals unprecedented detail about the regulatory role of CsrA, including novel binding targets
195 ovide intriguing insights into the potential regulatory role of differential DNA methylation in shapi
197 ccumulating evidence points to the important regulatory role of DUBs, the molecular basis of their re
204 try and replication and highlight a positive regulatory role of IFN-induced proteins in HIV-1 infecti
205 To elucidate this discrepancy, we analyzed a regulatory role of IkappaBzeta for the expression of ant
207 vances regarding both the pathogenic and the regulatory role of lymphocytes in SLE beyond the product
208 splicing of target mRNAs, demonstrating the regulatory role of m(6)A-switches on gene expression and
209 mation reverted to baseline, demonstrating a regulatory role of macrophage-derived ROS in autoimmunit
211 nally characterized circRNAs and support the regulatory role of mcircRasGEF1B in immune response duri
212 e in vivo effects of three C2 domains on the regulatory role of MCTP1 (FTIP1) in flowering time contr
215 ults indicate a nutritional rather than gene-regulatory role of miRNAs in the milk of newborn mice.
220 This study was undertaken to investigate the regulatory role of PN-1 in the pathogenesis of intervert
222 s from the present study demonstrate a novel regulatory role of PPARbeta/delta in modulating CYP2B10
224 roximal ribosome binding sites, suggesting a regulatory role of processing on translation initiation.
225 Although numerous reports have revealed the regulatory role of protein phosphorylation in photosynth
226 ominant pulmonary inflammation, suggesting a regulatory role of PTX3 in the development of allergic i
235 cap cells, the results point to a mechanical regulatory role of the cap cells in the lch5 organ.
236 rate complex and insight into the functional regulatory role of the ClpB NTD in protein disaggregatio
238 Among the three tRNA binding sites, the regulatory role of the exit (E) site, where deacylated t
239 he result strengthened our hypothesis on the regulatory role of the FOX TFs in enhancing mesoderm dif
240 to miR172c cleavage demonstrated the pivotal regulatory role of the miR172 node in the common bean-rh
241 ions will shed light on the newly discovered regulatory role of the risk locus in PC etiology and pro
242 non-canonical G-proteins with respect to the regulatory role of their G-domain in Ca(V)1.2 regulation
244 ording to glucose metabolism and suggest the regulatory role of this miRNA in energy homeostasis is h
246 prefrontal cortex (dmPFC), suggesting a key regulatory role of this region in motor performance.
247 eriments can be performed to investigate the regulatory role of thousands of oligonucleotide sequence
250 . (2017) provide novel perspectives into the regulatory role of WHIP-TRIM14-PPP6C signalosome in enha
251 n the Chlamydomonas genome suggest potential regulatory roles of 6mA in gene expression in eukaryotic
252 block, These findings confirm the important regulatory roles of AlucJHEH in A. lucorum and indicate
258 he Il6 promoter, further indicating opposite regulatory roles of IkappaBzeta at initial and resolutio
263 tive studies have demonstrated the important regulatory roles of microRNAs in vascular and neural dam
265 RNA transfer and add multiple layers to the regulatory roles of miRNAs and PMPs in tumor progression
268 utes to address and explore the function and regulatory roles of P. tricornutum lincRNAs in the conte
270 ing has accelerated discovery of the complex regulatory roles of small RNAs, but RNAs containing modi
272 R, we sought to investigate specifically the regulatory roles of the beta-arrestin2 isoform on expres
275 vivo, we found that IL-4 has a differential regulatory role on expression of IL-7Ralpha depending on
276 Our data suggest that rare codons have a regulatory role only if they are present within appropri
277 at exemplify Mac-1's pro-inflammatory versus regulatory roles particularly in the context of IgG immu
278 g genes, studies are uncovering the critical regulatory roles played by noncoding RNAs and noncoding
281 odel suggests that in addition to a possible regulatory role, Stem III could aid in preferential stab
282 iralis, eosinophils play an important immune regulatory role that promotes larval growth and survival
283 These findings, along with the well-known regulatory roles that SIRT1 plays in modulating both ana
284 s now apparent that AAT has important immune-regulatory roles that would be lost in AATD, yet adaptiv
286 pment, most likely through a transcriptional regulatory role, the precise nature of which remains to
288 hese regions play a variety of signaling and regulatory roles, they appear to be rapidly evolving at
291 variants are likely to have tissue-specific regulatory roles through joint contributions to biologic
292 pathway of Mei2 turnover, but rather plays a regulatory role to limit its accumulation or inhibit its
293 ur findings signify a unique transcriptional regulatory role to the highly enigmatic plant nuclear ph
295 issue-specific and that Dsx can exercise its regulatory role via two distinct mechanisms: as a sex-sp
299 g that the eIF4A binding domains may serve a regulatory role, with the C-terminal binding site having
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