ライフサイエンスコーパス: regulatory system

1 function or perturbations in the Wnt5a-Sfrp5 regulatory system.

2 ge that prompts reassessment of this classic regulatory system.

3 r-independent mechanism involving the RsmAYZ regulatory system.

4 ng the response regulator of a two-component regulatory system.

5 omponent responder (CovR)/sensor (CovS) gene regulatory system.

6 on in yycG, a component of the WalKR sensory regulatory system.

7 flagella through the ExoS/ChvI two-component regulatory system.

8 imate the state of a model of the sleep-wake regulatory system.

9 ly controlled by the EnvZ/OmpR two-component regulatory system.

10 omal function for uS12/Rps23 central to this regulatory system.

11 lly regulated by the RscS-SypG two-component regulatory system.

12 licy makers, and an informed and transparent regulatory system.

13 omponent of the fungal ambient pH-responsive regulatory system.

14 by dithiothrietol (DTT), through the MisR/S regulatory system.

15 stinal mucus, a bacterial toxin, and a toxin regulatory system.

16 rgets for the H. ducreyi CpxRA two-component regulatory system.

17 ut2) neurons as a key node of the wake-sleep regulatory system.

18 ion were governed by the SrrAB two-component regulatory system.

19 a-subunit through the ferredoxin-thioredoxin regulatory system.

20 iated motility is repressed by the PhoP/PhoQ regulatory system.

21 environment through the use of two-component regulatory systems.

22 bin formation, and perturbation of erythroid regulatory systems.

23 e expression by the DevRS/DosT and NarL/NarS regulatory systems.

24 ntain their homeostasis by multiple feedback regulatory systems.

25 increasing the robustness and plasticity of regulatory systems.

26 eptual framework for evolution of biological regulatory systems.

27 t well suited for a wide class of biological regulatory systems.

28 er, illustrating homeostatic behavior of DSB regulatory systems.

29 g gene functions and for engineering genetic regulatory systems.

30 erty-health relations by influencing emotion regulatory systems.

31 tress, causing wear and tear across multiple regulatory systems.

32 understanding of pathways and other complex regulatory systems.

33 th those seen in hypothalamic energy balance-regulatory systems.

34 to the workings of these complex eubacterial regulatory systems.

35 n in a manner similar to that by lantibiotic regulatory systems.

36 equires the contributions of both individual regulatory systems.

37 and neurologic significance of neuronal RNA regulatory systems.

38 used to describe allostery in two-component regulatory systems.

39 ple Michaelis-Menten type proteomic and gene regulatory systems.

40 n be used to discover and study key cellular regulatory systems.

41 ential steps requiring several two-component regulatory systems.

42 trolled by the RaxR/H and PhoP/Q 2-component regulatory systems.

43 al processes are still controlled by ancient regulatory systems.

44 luence organismal aging by affecting various regulatory systems.

45 the general properties of post-translational regulatory systems.

46 involve sophisticated genetic and epigenetic regulatory systems.

47 use may benefit from targeting cytoskeletal regulatory systems.

48 en may signal the degradation of body weight regulatory systems.

49 ere, we investigated the role of 2-component regulatory systems (2CSs) in plague because the latter a

50 phosphate pst transporter and the phoB-phoR regulatory system, a high-affinity ammonium amtB transpo

51 defensive medical practice, a less informed regulatory system, a lack of evidence-based sociopolitic

52 response regulators from other two-component regulatory systems, although a sensor for the system has

53 the end, this review will shed light on how regulatory systems, although seemingly conserved among b

54 The MARS complex may be part of a cellular regulatory system and a target for drug development.

55 s facilitated by the SsrA-SsrB two-component regulatory system and a type III secretion system encode

56 -bp deletion in the fasC gene of the fasBCAX regulatory system and an inactivating polymorphism in th

57 ve research and implementation involving the regulatory system and clinical community could substanti

58 uted to the structure of the transcriptional regulatory system and could therefore be a common featur

59 oadens the genes controlled by the flagellar regulatory system and implicates this system in co-ordin

60 n in synovial fluid, low activity of the Agr regulatory system and subsequent low production of the p

61 hus far the origin and evolution of both the regulatory system and SXL protein's sex-determination fu

62 of mHtt into IBs is policed by the RQC-Hsf1 regulatory system and that such compartmentalization, ra

63 ic variants as potential perturbants of gene regulatory system and to recover gene networks via analy

64 ose transcription is activated by the master regulatory system and whose promoter contains transcript

65 ng, group moralities reflect these different regulatory systems and emphasize social coordination thr

66 f cells and tissues reflects both the cell's regulatory systems and its state of intermediary metabol

67 As understanding of bacterial regulatory systems and pathogenesis continues to increas

68 ween the emergence and expansion of microRNA regulatory systems and the evolution of complex multicel

69 y cellular stress are key components of this regulatory system, and further adaptation of the metabol

70 e exopolysaccharide/quorum sensing ExpR/SinI regulatory system, and posttranslational regulation seem

71 ults in constitutive activation of the saeRS regulatory system, and we also demonstrate that repair o

72 regulated by the GAS CovR-CovS two-component regulatory system, and we demonstrated that bacteria wit

73 identified in bacteria, the BoxR/benzoyl-CoA regulatory system appears to be a widespread strategy to

74 pression is directly activated by the master regulatory system appears to control by antitermination

75 Cells with an intact complement negative regulatory system are protected from complement attack,

76 ith mutations in the CovR-CovS two-component regulatory system are selected for during localized GAS

77 The clinical implications of this novel regulatory system are shown as miR-515-5p is significant

78 d the importance of the PhoP/Q two-component regulatory system are similar to what has been shown in

79 Although several aspects of this regulatory system are well understood, no BirA superrepr

80 Advanced gene regulatory systems are necessary for scientific research

81 Cellular metabolic and regulatory systems are of fundamental interest to biolog

82 Here we describe an autogenous transgene regulatory system (ARES), based on the bacterial lac rep

83 the urinary tract and implicate the c-di-GMP regulatory system as an important factor in the persiste

84 ts that the PmrAB TCS controls expression of regulatory systems associated with the production of add

85 lts suggest that the mbd cluster recruited a regulatory system based on the MbdR regulator and its ta

86 Here, we evaluate cell-free regulatory systems based on T7 promoter-driven expressio

87 andom Forest (iJRF), which characterizes the regulatory system between miRNAs and mRNAs using a netwo

88 sors silence particular enhancers within cis-regulatory systems, blocking their expression throughout

89 sis involves the CrsR-CrsA partner-switching regulatory system, but the exact mechanism by which CrsR

90 f public hospitals, and institute a stronger regulatory system, but these changes have been slowed by

91 Their master regulatory system BvgAS controls expression of at least

92 nchiseptica rely on the global two-component regulatory system BvgAS to control expression of distinc

93 ltaneously decodes the perturbations of gene regulatory system by a large number of SNPs to identify

94 nst fast-evolving viruses, is also used as a regulatory system by the host.

95 ng to the local cell-population density in a regulatory system called quorum sensing.

96 ssion profiling revealed that the miR396-GRF regulatory system can alter the expression of 44% of the

97 Because activation of either regulatory system can compensate for failure of the othe

98 Alterations of this Pol IV-based regulatory system can generate potentially desirable and

99 l with customizable ligand inputs, RNA-based regulatory systems can greatly improve cellular therapie

100 Together, our results show that several regulatory systems can independently affect energy organ

101 criptional regulator/noncoding RNA virulence regulatory system, capable of causing S. aureus bloodstr

102 ic balancing, enhancing respiration, dynamic regulatory systems, chromosomal engineering, decoupling

103 characterized the role of the two-component regulatory system ColR/ColS in the pathogenicity of X. c

104 ll, our data indicate that the two-component regulatory system ColR/ColS is critical for X. citri sub

105 g peptide (CSP), via a classic two-component regulatory system ComDE.

106 The putative two-component regulatory system composed of EepR and EepS regulates he

107 for signal transduction is the two-component regulatory system, consisting of a sensor kinase (usuall

108 sensor kinase (LiaS) of a poorly defined GAS regulatory system contributes to a carrier phenotype thr

109 ity to adjust cardiac output and a number of regulatory systems control heart rate.

110 regulatory analysis to elucidate the genomic regulatory system controlling alx1 expression in time an

111 provide insight, here we investigate the cis-regulatory system controlling brinker (brk) expression i

112 The regulatory system controlling cyclin C-Med13p interactio

113 Collectively, our findings establish a regulatory system controlling developmentally deposited

114 The regulatory system controlling pheromone-induced plasmid

115 ns that constitute a previously unrecognized regulatory system controlling spread of IncI1 plasmids.

116 comprehensive picture of the transcriptional regulatory systems controlling periodic gene expression

117 In response to environmental cues, the BvgAS regulatory system controls expression of a spectrum of p

118 The WalRK two-component regulatory system coordinates gene expression that maint

119 The PhoPQ two-component regulatory system coordinates the response of Salmonella

120 algesia include activation of bimodal opioid regulatory systems, counter-regulatory mechanisms, neuro

121 the ecology of the community, by the role of regulatory systems coupled to the environmental conditio

122 is negatively regulated by the two-component regulatory system CovR/S.

123 ophils select mutations in the two-component regulatory system CovRS of group A Streptococcus (GAS) d

124 reptococcus (GAS) can have a mutation in the regulatory system CovRS, and this mutation can render st

125 responder (R)/sensor (S) two-component gene regulatory system (covRS), which enhances the virulence

126 cular underpinnings of a fructose metabolism regulatory system crucial for pathological growth.

127 n of mutational effects of a transcriptional regulatory system differs from the distributions of its

128 The diversity of regulatory systems encoded by bacteria provides an indic

129 Plant-microbe interactions involve numerous regulatory systems essential for plant defense against p

130 imal complexity, but it is unclear when this regulatory system evolved.

131 Humans' circadian, circannual, and metabolic regulatory systems evolved to be adaptive in environment

132 This regulatory system exerts combinatorial control not only

133 1157 DmdB enzymes, suggesting that a complex regulatory system exists in marine bacteria.

134 where DYNLL1 and CHICA-HMMR form part of the regulatory system feeding back spindle position to dynei

135 The reliance on this biochemical regulatory system for "exercising" synapses is reminisce

136 we describe a non-canonical, AGGF1-mediated regulatory system for endoplasmic reticulum stress signa

137 The UK self-regulatory system for exposing marketing violations reli

138 These findings suggest a more complex regulatory system for hematopoiesis than previously assu

139 A key regulatory system for protein stability is given by the

140 A key regulatory system for protein stability is given by the

141 onserved repeated sequences suggesting novel regulatory systems for both transcription and translatio

142 Both pathogens and hosts have complex regulatory systems for metal homeostasis.

143 icity is retained in classical two-component regulatory systems from this organism.

144 represent a previously unidentified internal regulatory system governing the establishment of adaptiv

145 Staphylococcus aureus uses the two-component regulatory system GraRS to sense and respond to host def

146 The two-component regulatory system, GraRS, appears to be involved in stap

147 The Staphylococcus aureus two-component regulatory system, GraRS, is involved in resistance to k

148 In this study, we identified a two-component regulatory system GrvRS as the main regulator of ace exp

149 Here, we show that the agr gene regulatory system has a crucial role in the development

150 It appears that the cyclic-AMP-CRP regulatory system has been adapted to respond to distinc

151 The Cpx two-component regulatory system has been shown in Escherichia coli to

152 that, to preserve function, an entire redox regulatory system has to be retained within its original

153 Several regulatory systems have been described to govern the ini

154 inducer in vivo, suggests that this type of regulatory system holds great promise for applications i

155 ca was also dependent on the BvgAS virulence regulatory system; however, in contrast to the case in B

156 o assess similarities with the known hormone regulatory system in Arabidopsis.

157 r results suggest a role of the miR858-MYB83 regulatory system in finely balancing gene expression pa

158 new information about this poorly described regulatory system in GAS.

159 peroxiredoxins (Prxs) comprises a key redox regulatory system in mammalian cells.

160 gnaling, suggesting a universal role of this regulatory system in multiple pathways in Drosophila.

161 iae but not in S. aureus, showing a feedback regulatory system in S. pneumoniae that is absent in S.

162 fic mutations in the GacS/GacA two-component regulatory system in swarming colonies of Pseudomonas pr

163 Perturbation of this regulatory system in the brain may contribute to the dev

164 argument that eCB signaling is an important regulatory system in the brain that largely functions to

165 xistence of an evolutionarily conserved gene regulatory system in the bundle sheath.

166 ion of the Y. pestis PhoP-PhoQ two-component regulatory system in the flea.

167 pose that cell-cycle events are ordered by a regulatory system in which a master oscillator, based on

168 the advantage of characterizing multi-switch regulatory systems in terms of their constituent switche

169 mechanisms and their interactions with other regulatory systems in the control of keratinocyte differ

170 hese results highlight the importance of the regulatory systems in the evolution and adaptation of ba

171 To determine whether cytoskeletal regulatory systems in the oPFC influenced decision-makin

172 ere, we explore the potential of elucidating regulatory systems in varied cell types using computatio

173 Two-component regulatory systems, in which phosphorylation controls th

174 adly applicable to elucidating mechanisms of regulatory systems including those that are kinetically

175 -28 as an example to illustrate how distinct regulatory systems, including miRNAs and multiple protei

176 es much of the known biochemistry of the IDH regulatory system into a single quantitative framework a

177 the ventral tissue are integral parts of the regulatory system involved in the development of HSCs.

178 Thus, MCV has evolved a regulatory system involving SCF(Fbw7) that controls vira

179 Together, these results suggest a miR-145 regulatory system involving the Akt and C/EBP-beta, whic

180 In summary, our results show a complex regulatory system involving TP53, KRAS, and let-7a.

181 ation threshold, the AgrC-AgrA two-component regulatory system is activated through a cascade of phos

182 We infer that the vertebrate Hox bipartite regulatory system is an evolutionary novelty generated b

183 The Gac/Csr regulatory system is conserved throughout the gamma-prot

184 is prrA-prrB (Rv0903c-Rv0902c) two-component regulatory system is expressed during intracellular grow

185 The biological regulatory system is highly dynamic.

186 We find that the regulatory system is highly robust to variations in cofa

187 cate that while full activation of the BvgAS regulatory system is required for colonization and sever

188 we demonstrate that the phoPR two-component regulatory system is required to slow Mtb growth at acid

189 The core of this regulatory system is the PhyR protein, which contains a

190 re we investigate two levels at which the pH regulatory system is transcriptionally moderated by pH a

191 The importance of this complex regulatory system is underscored by the identification o

192 m that involves the Csr and BarA/UvrY global regulatory systems is exposed.

193 n explore different approaches for composing regulatory systems, leading to the implementation of ind

194 redicted to be a member of a three-component regulatory system (LiaFSR) involved in the stress-sensin

195 ncing, implying that a distinctive chromatin regulatory system may act at rDNA genes.

196 This regulatory system may represent a mechanism by which aux

197 In X. campestris, a regulatory system mediated by the signal molecule DSF co

198 Hence, a conserved WUS/WOX-CLV regulatory system might control cell proliferation and d

199 Vibrio cholerae's CarRS two-component regulatory system negatively regulates expression of vps

200 been studied as a paradigmatic two-component regulatory system not only to dissect structural and fun

201 creasing evidence that perturbations in this regulatory system occur in the hypertrophied and failing

202 eractions can achieve an emergent and robust regulatory system of collective foraging activity in ant

203 arises in the isocitrate dehydrogenase (IDH) regulatory system of Escherichia coli, which was shown i

204 ox gradient, which is interpreted by the cis-regulatory system of the nodal gene to cause its express

205 Novel relationships, common to the regulatory systems of all endotherms, are found to relat

206 o function broadly within the signalling and regulatory systems of the cell.

207 ragility as a paradigm within this and other regulatory systems perturbed in cancer could, in large p

208 dly acidic pH activates the master virulence regulatory system PhoP/PhoQ in the facultative intracell

209 Genes controlled by the two-component regulatory system PhoPQ modify lipopolysaccharides.

210 g aerobic nitrate metabolism, the DevRS/DosT regulatory system plays a primary role that is augmented

211 ostasis, emulating the role of the CusR/CusS regulatory system present in other enteric bacteria.

212 The Set2-Rpd3 regulatory system prevents cryptic promoter function wit

213 sequences and the characterization of global regulatory systems provide an important starting point i

214 e architecture of the ICEMlSym(R7A) transfer regulatory system provides an example of how a set of mo

215 The CI regulatory system provides an intriguing comparison with

216 This unique acid-activated regulatory system provides insights into an evolutionary

217 This natural auto-regulatory system provides the basis for engineering IL-

218 a structural feature common to many cellular regulatory systems: regulators are typically either boun

219 Two-component regulatory systems represent potential therapeutic targe

220 y highlighting how sRNAs converge with known regulatory systems required for biofilm formation.

221 This regulatory system requires TFL1 expression to rise in pr

222 l enhancer-binding protein and two-component regulatory system response regulator activated by acetyl

223 e Ti plasmid-encoded VirA/VirG two-component regulatory system, resulting in the transcriptional acti

224 odel microbial community is dependent on the regulatory system's influence on the distribution of dis

225 system as a spatiotemporally controlled gene regulatory system, several approaches of conditional act

226 ies scale up, there is no better time to put regulatory system strengthening squarely on the global h

227 based on experimental perturbations of gene regulatory systems such as gene knock-out experiments, f

228 daptation is often mediated by two-component regulatory systems, such as the PhoP/PhoQ system that re

229 Specific key regulatory systems susceptible to programming may influe

230 gulated, in part, by the SrrAB two-component regulatory system (TCRS).

231 Shigella flexneri two-component regulatory systems (TCRS) are responsible for sensing ch

232 ic levels of metals, including two-component regulatory systems (TCRS).

233 systems that are composed of a two-component regulatory system (TCS) and an ATP-binding cassette (ABC

234 ens coordinate virulence using two-component regulatory systems (TCS).

235 ted cognate regulation and the two-component regulatory system TCS06 (RR06/HK06) that regulates the e

236 Two-component gene regulatory systems (TCSs) are a major mechanism by which

237 In bacterial two-component regulatory systems (TCSs), dephosphorylation of phosphor

238 the central component of a conserved global regulatory system that activates or represses gene expre

239 a central or peripheral role for BKs in the regulatory system that controls adipose tissue and weigh

240 Csr is a conserved global regulatory system that controls expression of several hu

241 a previously unknown small peptide-mediated regulatory system that controls GAS virulence factor pro

242 r results establish that PmrAB is the global regulatory system that controls lipopolysaccharide modif

243 atomic scale, of a conserved transcriptional regulatory system that controls the cellular and infecti

244 Many elements of the regulatory system that controls this process are known,

245 kinase-mediated ER-PM cross-talk comprises a regulatory system that ensures cellular integrity under

246 regulators, including ArlRS, a two component regulatory system that has been shown to negatively regu

247 A regulatory system that integrates science and welfare is

248 we provide a complementary analysis of this regulatory system that investigates the roles of both De

249 are regulated by the PhoR/PhoB two-component regulatory system that is used to sense and respond to P

250 opsis has a highly intricate transcriptional regulatory system that may allow for the optimization of

251 S. aureus AirSR is a redox-dependent global regulatory system that plays important roles in gene reg

252 CarRS is a two-component regulatory system that positively regulates almEFG expre

253 luenzae strain 2019 FirRS is a two-component regulatory system that senses ferrous iron and autoregul

254 We modeled our results to propose a regulatory system that transmits signals from differenti

255 Today, we are faced with a regulatory system that, weakened by decades of limited r

256 tory control primarily through two-component regulatory systems that allow for sensing and responding

257 mone effects on the cardiovascular and water regulatory systems that are associated with blood pressu

258 These malignancies co-opt transcriptional regulatory systems that characterize their normal B cell

259 tivating mutations within genes encoding two regulatory systems that control the expression of import

260 The regulatory systems that control the synthesis and regene

261 oordination of diverse cytological events by regulatory systems that drive the cell from mitosis into

262 tissues exhibit striking similarities in the regulatory systems that establish gene expression patter

263 dels: first, the combinatorial, hierarchical regulatory systems that generate the orderly, synchroniz

264 e compensatory action of a network of growth regulatory systems that minimize developmental perturbat

265 n rhythmicity, therefore bridging two global regulatory systems that modulate all aspects of bodily f

266 at includes the hptRS (a novel two-component regulatory system), the hptA (a putative phosphate senso

267 Despite the importance of this fine regulatory system, the molecular mechanisms underlying t

268 potential regulatory mechanisms of a global regulatory system, the well-studied carbon storage regul

269 evidence for the emergence of an epigenetic regulatory system through recruitment of selfish element

270 gher organism develops a complex translation regulatory system to achieve accurate and flexible gene

271 lusion, BAG and URX neurons work as a neural-regulatory system to counterbalance each other via diffe

272 s to explain the contribution of the Crc/Hfq regulatory system to evolutionary fitness of pseudomonad

273 nd Typhimurium, have evolved a two-component regulatory system to exist inside Salmonella-containing

274 he glucose transporter GLUT4 as a glycolytic regulatory system to meet the activity-driven increase i

275 omplexes are important, and that allows this regulatory system to respond rapidly to change in cellul

276 nd subsequently interacts with the VirA/VirG regulatory system to stimulate virulence (vir) gene expr

277 ountries, demonstrate the essential value of regulatory systems to low- and middle-income countries.

278 Bacteria utilize multiple regulatory systems to modulate gene expression in respon

279 gnal transduction by classical two-component regulatory systems typically entails an intermolecular p

280 , the HPT system consists of a two-component regulatory system (UhpAB) and a phosphate sensor protein

281 The flagellar regulatory system ultimately influences sigma(28) activi

282 is instrumental in interrogating eukaryotic regulatory systems using heterogeneous data.

283 studying specific, experimentally tractable regulatory systems using the tools of modern systems bio

284 ported in vitro when the VirAG two-component regulatory system was overexpressed in trans.

285 erential equation model for a single genetic regulatory system, we examine the dynamical effects of n

286 ion of the P. aeruginosa AlgZR two-component regulatory system were examined.

287 of pilus expression, and two-component gene regulatory systems were shown to affect the bacterial ph

288 latory role played by the template itself in regulatory systems where DNA is known to be highly bent.

289 t system (also called GrrS/GrrA) is a global regulatory system which is highly conserved among gamma-

290 posed when PrEP was not approved through the regulatory system, which could have affected uptake; and

291 ntiporters, represent a carefully tuned self-regulatory system, which drives the cytoplasmic pH back

292 manner that required the BaeSR two-component regulatory system, which is known to respond to extracyt

293 regulated by the WalRK (VicRK) two-component regulatory system, which positively regulates expression

294 pH and CAMP through the PhoPQ two-component regulatory system, which stimulates lipid A remodeling,

295 Csr is a conserved global regulatory system, which uses the sequence-specific RNA-

296 the gacA/gacS bacterial two-component global regulatory system while leaving the plasmid sequence int

297 nin strongly induces the LiaRS two-component regulatory system, while moenomycin almost exclusively i

298 of E. coli respond by activating the TorTSR regulatory system with consequent induction of TMAO redu

299 Here we consider the evolution of such regulatory systems, with a particular emphasis on the ro

300 Thus, this universal regulatory system within the NPC is crucial to control l