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1 pretreatment) also suppressed E2-potentiated reinstatement.
2 of alcohol approach behaviors and attenuates reinstatement.
3 cient mutant of AKAP150 also impairs cocaine reinstatement.
4 ing to a reduction in subsequent cue-induced reinstatement.
5 also correlate with the level of hippocampal reinstatement.
6 ck-out mice prevented foot-shock-induced CPP reinstatement.
7 mental area are necessary for these forms of reinstatement.
8 is necessary for stress-induced nicotine CPP reinstatement.
9 ited in a dopamine-dependent manner to drive reinstatement.
10 acellular mechanism by which stress leads to reinstatement.
11 d neurotransmitter systems in stress-induced reinstatement.
12 ng activity in D2-MSNs augmented cue-induced reinstatement.
13 y results from rat studies on stress-induced reinstatement.
14 cimol and baclofen decreased context-induced reinstatement.
15 ine, followed by cue-induced and drug-primed reinstatement.
16 ) blockade in the AId similarly reduced cued reinstatement.
17 statement or sucrose self-administration and reinstatement.
18 ppocampal pattern completion and neocortical reinstatement.
19 PIc activity does not influence cue-induced reinstatement.
20 ex to the nucleus accumbens is implicated in reinstatement.
21 ially to reduce drug self-administration and reinstatement.
22 n the dose-response curve for cocaine-primed reinstatement.
23 ially mimicked the drug's systemic effect on reinstatement.
24 during context-induced, but not cue-induced reinstatement.
25 activation is necessary for E2 to potentiate reinstatement.
26 ic prefrontal cortex (PrL-PFC) to potentiate reinstatement.
27 se sessions, but had no effect on subsequent reinstatement.
28 o LS specifically attenuated context-induced reinstatement.
29 in the DG and produced compulsive-like drug reinstatement.
30 mpulsive-like context-driven methamphetamine reinstatement.
31 is during abstinence in compulsive-like drug reinstatement.
32 elf-administration but before extinction and reinstatement.
33 variectomized to isolate estrogen effects on reinstatement.
34 uorescence-activated cell sorting to isolate reinstatement-activated Fos-positive neurons from Fos-ne
36 nstated sucrose seeking, nor was potentiated reinstatement after mGluR2/3 blockade reduced by blockin
38 creased responding during drug prime-induced reinstatement-an effect that was normalized by inhibitin
39 kdown prevented ceftriaxone from attenuating reinstatement and from upregulating GLT-1 and resulted i
40 also prevented ceftriaxone from attenuating reinstatement and from upregulating xCT expression, with
41 algorithm, we quantify the timescale of the reinstatement and identify brain regions that show signi
43 etics, we show modulation of context-induced reinstatement and reacquisition of alcohol seeking via d
46 A and VP --> STN pathways in context-induced reinstatement and reacquisition we used a chemogenetic d
47 involved in the regulation of cocaine-primed reinstatement, and activation of both brain regions is s
48 urther suggesting that garcinol's effects on reinstatement are through reconsolidation-based mechanis
49 ese areas also show evidence of anticipatory reinstatement as subjects listen to a familiar narrative
50 Alcohol self-administration and cue-induced reinstatement behavior was measured after intracerebrove
51 C pathway positively correlated with cocaine reinstatement behavior, unlike BLA or vSub inputs to NAc
53 showed beneficial effects in preventing fear reinstatement, but differed in the groups they targeted.
56 ry mediating the facilitation of cue-induced reinstatement by NPS involves structures critically invo
57 O mice showed recovery from hyperalgesia and reinstatement by NTX; (3) there was no MOR internalizati
59 Three measures of t-SP were assayed during reinstatement: dendritic spine morphology, alpha-amino-3
60 e effects of vmPFC activation on cue-induced reinstatement depended on prior extinction training, con
63 , the strength of a memory's unique episodic reinstatement during retrieval was inversely related to
64 on-related brain activity showed evidence of reinstatement during subsequent periods of neutral stimu
65 Together, these findings suggest that Ube3a reinstatement early in development may be necessary to p
66 dle temporal gyrus and the left hippocampus, reinstatement effects between the retrieval phases corre
67 erved widespread within- and between-subject reinstatement effects within a posterior midline core me
68 ntral pallidal neurons blocked the augmented reinstatement elicited by chemogenetic regulation of eit
70 ons are (1) The phenomenon of stress-induced reinstatement, first shown with an intermittent footshoc
75 being a common locus for different forms of reinstatement, fundamental aspects of neural circuitry f
76 mory should be restabilized had no effect on reinstatement, further suggesting that garcinol's effect
77 eurons was sufficient to induce nicotine CPP reinstatement, identifying an anatomically specific intr
79 whether PACAP is also involved in producing reinstatement in a model of stress-induced relapse to dr
81 provide support for the role of oscillatory reinstatement in memory retrieval.SIGNIFICANCE STATEMENT
82 th rimonabant and AM4113 reduced cue-induced reinstatement in monkeys trained to self-administer coca
85 d extinction, but each treatment potentiates reinstatement in response to an otherwise subthreshold c
86 uation of nicotine and THC reinforcement and reinstatement in squirrel monkeys by the CB1-receptor in
88 f mGluR5 in NAcore recapitulated cue-induced reinstatement in the absence of drug-associated cues.
92 bens shell of Sprague-Dawley rats attenuates reinstatement induced by either cocaine or a D1DR agonis
93 nduced reinstatement of alcohol seeking, and reinstatement induced by injections of U50,488 (0, 0.3,
94 , we correlated regional Fos expression with reinstatement induced by the most effective U50,488 dose
96 eval manipulation on cocaine-priming-induced reinstatement is mediated by regulation of AMPA-receptor
102 either the temporal precision of study-phase reinstatement nor the processing stage at which the rein
105 ed that verbal memory retrieval leads to the reinstatement of activity across regions of the brain th
107 ting to NAc, but not BLA, blocks cue-induced reinstatement of alcohol seeking and neither pathway is
108 BNST is a critical site for U50,488-induced reinstatement of alcohol seeking and suggest that KOR/dy
111 s of nor-BNI (4 mug/side) on U50,488-induced reinstatement of alcohol seeking, and reinstatement indu
112 C-->NAc pathway is necessary for cue-induced reinstatement of alcohol seeking, expand our understandi
117 mg/kg) was tested in a model of cue-induced reinstatement of alcohol-seeking behavior in post-depend
121 euronal activation induced by stress-induced reinstatement of alcohol-seeking using c-Fos immunohisto
124 that reactivation was only required for the reinstatement of assembly patterns whose expression was
125 ory retrieval-extinction procedure decreases reinstatement of cocaine and heroin seeking in rats and
128 ative subunits of AMPK increased cue-induced reinstatement of cocaine seeking and enhanced mTORC1 and
129 ctive subunits of AMPK decreased cue-induced reinstatement of cocaine seeking and inhibited the mamma
130 bility of ceftriaxone to prevent cue-induced reinstatement of cocaine seeking and normalize glutamate
131 This disconnection attenuated cue-induced reinstatement of cocaine seeking but had no effect on re
132 of vmPFC neurons with the Gq-DREADD reduced reinstatement of cocaine seeking elicited by cocaine-ass
133 d corticosterone, potentiates cocaine-primed reinstatement of cocaine seeking following self-administ
136 administration of CNO inhibited cue-induced reinstatement of cocaine seeking in rats extinguished fr
137 SA and prolonged (over 5 weeks) increases in reinstatement of cocaine seeking induced by foot-shock s
138 rum corticosterone and significantly greater reinstatement of cocaine seeking than the control group,
139 rgic inputs to nucleus accumbens during cued reinstatement of cocaine seeking versus sucrose seeking.
140 found to differentially promote cue-induced reinstatement of cocaine seeking via the ventral pallidu
142 rm treatment with ceftriaxone attenuates the reinstatement of cocaine seeking while increasing the fu
143 e findings elucidate the importance of LS in reinstatement of cocaine seeking, and indicate that dors
144 arker of neural activity) during cue-induced reinstatement of cocaine seeking, but only subpopulation
145 lity of ceftriaxone to attenuate cue-induced reinstatement of cocaine seeking, each protein uniquely
146 the NAc core is critical for the cue-induced reinstatement of cocaine seeking, which may be mediated
157 essive ratio schedule of reinforcement), and reinstatement of cocaine taking in rats allowed either s
159 FICANCE STATEMENT Ceftriaxone attenuates the reinstatement of cocaine, alcohol, and heroin seeking.
160 e examined Fos expression during cue-induced reinstatement of cocaine- and sucrose-seeking in prelimb
161 significant attenuation of yohimbine-induced reinstatement of cocaine-seeking after intra-CeA SB-3348
162 results suggest that AKAP150 facilitates the reinstatement of cocaine-seeking behavior by amplifying
163 the NpHR-mCherry groups disrupted CS-induced reinstatement of cocaine-seeking behavior relative to (i
164 n the nucleus accumbens is necessary for the reinstatement of cocaine-seeking behavior, an animal mod
167 sion, would block BDNF's ability to suppress reinstatement of cocaine-seeking in rats with a cocaine
171 Our data suggest that temporally compressed reinstatement of cortical activity is a feature of cued
174 WIN), in order to assess measures of relapse/reinstatement of drug seeking and long-term effects on c
175 the shell attenuated cocaine priming-induced reinstatement of drug seeking and was associated with in
176 system has been implicated in stress-induced reinstatement of drug seeking for other commonly abused
177 tem plays a conserved role in stress-induced reinstatement of drug seeking for prototypical substance
178 mory processes and that nuclear HDAC5 limits reinstatement of drug seeking independent of NPAS4.
179 ished lever pressing and tested the rats for reinstatement of drug seeking induced by cocaine-paired
180 and the roles of these VP output pathways in reinstatement of drug seeking remain poorly understood.
183 hether they reduce drug self-administration, reinstatement of drug seeking, and incubation of drug cr
184 se consequences, and very robust cue-induced reinstatement of drug seeking, especially in a subset of
196 the importance of multiple neuropeptides in reinstatement of drug use, we formulated intranasal insu
197 ng behavior, and (2) priming- or cue-induced reinstatement of drug-seeking behavior in abstinent subj
198 ine self-administration, and cocaine-induced reinstatement of drug-seeking behavior, whereas R-MOD in
200 ding the mechanisms by which stress triggers reinstatement of drug-seeking behaviors is particularly
205 ognition (AR) yields enhanced event-specific reinstatement of encoding patterns compared to non-assoc
206 or STN are recruited during context-induced reinstatement of extinguished alcohol seeking in rats.
208 a concentrations) potentiated cocaine-primed reinstatement of extinguished cocaine-induced conditione
209 was more effective than 2 in attenuating the reinstatement of extinguished cocaine-seeking behavior i
210 d for self-administered intravenous meth and reinstatement of extinguished meth seeking in male and f
211 Conditioned place preference, extinction and reinstatement of extinguished preference in response to
212 ntions would be more effective to reduce the reinstatement of fear in subjects genetically predispose
214 been shown to contribute to context-induced reinstatement of heroin, cocaine, and alcohol seeking, b
215 male and female rats, meth demand predicted reinstatement of meth seeking, and systemic oxytocin dec
217 nt with the antibiotic, ceftriaxone, blocked reinstatement of morphine-evoked conditioned place prefe
218 Our data therefore provide a link between reinstatement of neural activity in the cortex and spont
219 tive memory recall is thought to involve the reinstatement of neural activity patterns that occurred
220 that episodic memory retrieval involves the reinstatement of neural activity that was present when w
223 esults are consistent with the proposal that reinstatement of neural oscillations during retrieval su
225 al stressor yohimbine (2 mg/kg, i.p.) induce reinstatement of nicotine CPP in a norbinaltorphimine (n
229 on, and mechanisms that this system plays in reinstatement of nicotine seeking has not been character
230 intravenous nicotine self-administration and reinstatement of nicotine seeking induced by nicotine pr
231 nt with reduced nicotine reward; (3) blocked reinstatement of nicotine seeking induced by reexposure
232 se, we hypothesized that stress would induce reinstatement of nicotine seeking-like behavior in a KOR
236 tial patterns of brain activity has revealed reinstatement of recently-experienced events throughout
237 t after the clearance phase leads to a rapid reinstatement of robust tau pathology once soluble tau e
239 nisms governing the initiation, closure, and reinstatement of sensitive period plasticity has emerged
242 ce preference for high-fat food, cue-induced reinstatement of sucrose-seeking, and motivation to work
243 ally in the bronchial epithelium resulted in reinstatement of susceptibility to fungal allergen-induc
245 of event boundaries triggered a rapid memory reinstatement of the just-encoded sequence episode.
248 this hypothesis through cerebellum-specific reinstatement of Ube3a, which ameliorated cerebellar lea
252 inction training, rats underwent cue-induced reinstatement or an 'inactivation-alone' extinction test
253 reinstatement, with no effect on cue-induced reinstatement or sucrose self-administration and reinsta
254 study, we use a conditioned place preference/reinstatement paradigm in mice to directly test the hypo
256 Here, we used a modified self-administration/reinstatement procedure combined with anatomical, pharma
257 Using a conditioned place preference (CPP) reinstatement procedure in mice, we show that both foot-
260 ion showed that oxytocin reduced cue-induced reinstatement response in dependent rats-an effect that
261 As Long-Evans rats did not show a robust reinstatement response to nicotine, we used alcohol-pref
262 rring rats (P-rats) that display much higher reinstatement responses to nicotine than Long-Evans rats
263 or intra-VTA) before a single extinction or reinstatement session, while having no immediate effect
264 L inhibition after lever presses during cued reinstatement sessions increased cocaine seeking during
266 th 3 mg/kg of ADX71441 before stress-induced reinstatement significantly decreased c-Fos expression i
268 e affect (NA)) followed by an analog smoking reinstatement task for which participants could earn mon
270 ine across progressive ratio, extinction and reinstatement testing, but had no effect on food reinfor
272 anced cocaine seeking measured in extinction/reinstatement tests following an extended 3 week withdra
274 tivation significantly decreased cue-induced reinstatement to both cues, indicative of reconsolidatio
276 ith CRF1 receptors in this region, regulates reinstatement to cocaine seeking, but not food seeking,
278 ependently inhibited cue- and cocaine-primed reinstatement to cocaine, but did not affect locomotor a
279 e activity of kappaORs governs the prolonged reinstatement to cocaine-seeking observed after cold wat
280 rst discuss the generality of stress-induced reinstatement to different drugs of abuse, different str
283 g behavior, pretreatment with E2 potentiated reinstatement to the ordinarily subthreshold cocaine dos
285 the neuropeptide S (NPS) system exacerbates reinstatement vulnerability to cocaine and alcohol via s
286 This viral-mediated attenuation of cocaine reinstatement was accompanied by decreased phosphorylati
290 spase strategy, the intensity of cue-induced reinstatement was correlated with the extent of selectiv
293 gulated by presynaptic mGluR2/3, and sucrose reinstatement was potentiated following mGluR2/3 blockad
294 erone treatment to potentiate cocaine-primed reinstatement was recapitulated by intra-PL injection of
296 ng showed an overall effect in reducing fear reinstatement, whereas pharmacological memory enhancemen
297 t not food seeking, depending on the type of reinstatement, whereas PIc activity does not influence c
298 ts demonstrate that riluzole impairs cocaine reinstatement while rectifying several cellular adaptati
299 ffects of cocaine and attenuated drug-primed reinstatement, with no effect on cue-induced reinstateme
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