ライフサイエンスコーパス: relaxant

1 O2 and VCO2 seen without the use of a muscle relaxant.

2 ed with rocuronium, a nondepolarizing muscle relaxant.

3 ete as predicted by its efficacy as a muscle relaxant.

4 or is prostacyclin (PGI(2)), a smooth muscle relaxant.

5 abor is prostacyclin (PGI2), a smooth muscle relaxant.

6 r to labor, prostacyclin, is a smooth muscle relaxant.

7 xamine cisatracurium, a commonly used muscle relaxant.

8 scription proton-pump inhibitors, and muscle relaxants.

9 impaired by volatile anesthetics and muscle relaxants.

10 ational anaesthetics and depolarising muscle relaxants.

11 identifying cross-reactivity between muscle relaxants.

12 atric airway has reduced the need for muscle relaxants.

13 tic and anti-inflammatory therapy and muscle relaxants.

14 ere highly protected from water-soluble spin relaxants.

15 line receptors are clinically used as muscle relaxants.

16 common medication classes were smooth-muscle relaxants (16 trials), bulking agents (13 trials), proki

17 ings to respond to the endothelium-dependent relaxant acetylcholine, both during in vitro hyperglycem

18 that are probably independent of its muscle-relaxant action.

19 ith similar in vitro potency as 4 as well as relaxant activity on bladder smooth muscle in vivo when

20 lgesic agent without centrally acting muscle relaxant activity.

21 The pericyte relaxant adenosine increased capillary diameter by 21% a

22 bitor), but not hydralazine (a smooth muscle relaxant), ameliorated colitis in RenTgMK mice, although

23 viorally, SH-I-048A induced sedative, muscle relaxant and ataxic effects, reversed mechanical hyperal

24 ate that PDE4D plays a key role in balancing relaxant and contracting cues in airway smooth muscle, s

25 2 following the administration of the muscle relaxant and the observation that turning a patient into

26 constructs were able to relax in response to relaxants and contract in response to contractile agents

27 Specific relaxants and doses can be chosen to suit the clinical c

28 d between the sexes, particularly for muscle relaxants and opioids.

29 t antimicrobial, vasodilating, smooth muscle relaxant, and growth factor stimulating effects.

30 gical needs should dictate the use of muscle relaxants, and alternatives to their use should be consi

31 istamines, antihypertensives, antimalarials, relaxants, and bronchodilators.

32 ement strategy that avoids sedatives, muscle relaxants, and physical restraints, and allows liberal b

33 rounding ECT, cardiac effects, use of muscle relaxants, and the consent process.

34 te produces the sedative, anxiolytic, muscle relaxant, anticonvulsant and cognition-impairing effects

35 e discovery of the nonsedating potent muscle relaxant, antiinflammatory, and analgesic agent (E)-2-(4

36 paper describes the synthesis and the muscle relaxant, antiinflammatory, and analgesic structure-acti

37 steroidal anti-inflammatory drugs and muscle relaxants are a very effective combination for the effec

38 acting and low doses of medium-acting muscle relaxants are appropriate for the typically short period

39 Smooth-muscle relaxants are beneficial when abdominal pain is the pred

40 Skeletal muscle relaxants are effective for short-term pain relief in ac

41 Muscle relaxants are still indicated for intubation and procedu

42 c drugs (inhalational anesthetics and muscle relaxants) are described.

43 which is currently FDA approved as a muscle relaxant, as a safe and novel treatment of EA2.

44 olytic activity but was devoid of the muscle relaxant/ataxic effects of "classical" 1,4-benzodiazepin

45 To understand this potential contractile-relaxant autoregulatory mechanism, production of cardiac

46 discovery of the GABA(B) agonist and muscle relaxant baclofen, there have been substantial advanceme

47 d gamma-cyclodextrin and the first selective relaxant binding agent), forms very tight complexes in a

48 Selective relaxant binding agents offer a new approach for the rev

49 Obesity impairs the relaxant capacity of adipose tissue surrounding the vasc

50 nce of membranes and of a water-soluble spin relaxant (chromium oxalate) has been developed to determ

51 ne; the antiemetic benzquinamide; the muscle relaxant cyclobenzaprine; the analgesic nefopam; and the

52 receptor (RYR) channels, the skeletal muscle relaxant dantrolene has proven to be both a valuable exp

53 The skeletal muscle relaxant dantrolene inhibits the release of Ca2+ from th

54 In tracheal intubation, the use of muscle relaxants decreases laryngospasm.

55 ound nitroxide by a membrane-impermeant spin relaxant depends on the distance (up to tens of angstrom

56 Airway relaxant dose-response curves were constructed to measur

57 e and factors affecting the choice of muscle relaxant drugs in pediatric anesthesia.

58 lled trials concluded that the smooth muscle relaxant drugs tamsulosin and nifedipine assisted stone

59 targeted by a variety of anticonvulsant and relaxant drugs.

60 nic and anticholinergic/direct smooth muscle relaxant drugs.

61 t sites in the MRF would be effective muscle relaxants during pregnancy, prior to the fall in progest

62 drugs has reduced the requirement for muscle relaxants during surgery.

63 overy of the potent, centrally acting muscle relaxant (E)-2-(4,6-difluoro-1-indanylidene)acetamide, 1

64 m lacking the acidic C terminus had the same relaxant effect as wild-type telokin, whereas the C-term

65 nly terbutaline showed a differential airway relaxant effect between proximal and distal airways, as

66 This relaxant effect contributed to a beta-adrenoceptor-media

67 phospholamban phosphorylation and a de novo relaxant effect following beta(2)-AR stimulation, conver

68 The relaxant effect is thought to be due primarily to stimul

69 horylation by CaMKII and is essential to the relaxant effect of beta-adrenergic stimulation.

70 The relaxant effect of beta-receptor stimulation was absent

71 ontribution of myofilament properties to the relaxant effect of beta-stimulation may be of greater si

72 Therefore, ICCs and SMCs jointly mediate the relaxant effect of enteric NO.

73 hich is independent of, but additive to, the relaxant effect of Ser(16) phosphorylation, resulting in

74 hway providing a molecular mechanism for the relaxant effect of the hormone.

75 in-converting enzymes (ACE), and direct vaso-relaxant effect or calcium channel modulation.

76 iod (n = 10), suggesting that some of Epac's relaxant effect relies upon vascular cell hyperpolarizat

77 phosphorylation of telokin up-regulates its relaxant effect.

78 pathway, resulting in positive inotropic and relaxant effects in the heart.

79 d increased sensitivity of the muscle to the relaxant effects of 8-Br-cyclic guanosine monophosphate

80 -K channels appear to indirectly mediate the relaxant effects of a number of agents, activators that

81 d sensitivity of airway smooth muscle to the relaxant effects of endogenous NO.

82 After measurement of the contractile and relaxant effects of epinephrine (10 micromol/L) or zinte

83 in the study suggests that the smooth muscle relaxant effects of heptanol may be non-specific and unr

84 To evaluate the relaxant effects of other TLRs.

85 epleted of its endogenous telokin, and their relaxant effects were mutually potentiated.

86 In addition to its vascular relaxant effects, cAMP is known to protect endothelial c

87 ctor through which beta-agonists exert their relaxant effects.

88 The endothelium relaxant factor nitric oxide is well known to mediate mi

89 n are NSAIDs, acetaminophen, skeletal muscle relaxants (for acute low back pain), and tricyclic antid

90 that NSAIDs, acetaminophen, skeletal muscle relaxants (for acute low back pain), and tricyclic antid

91 y of GRK2/3 regulation of procontractile and relaxant G-protein-coupled receptors in ASM.

92 As the quality of currently available relaxants has improved, the need to combine relaxants to

93 e effects of the intubating dose of a muscle relaxant have worn off.

94 Treatment with a muscle relaxant impairs mouth opening, supporting the hypothesi

95 de, SMP) was recently identified as a muscle relaxant in the starfish Patiria pectinifera.

96 etic drugs have influenced the use of muscle relaxants in children.

97 a family of neuropeptides that act as muscle relaxants in echinoderms.

98 nce for efficacy was shown for smooth-muscle relaxants in patients with abdominal pain as the predomi

99 have reduced or obviated the need for muscle relaxants in pediatric anesthesia.

100 may improve upon currently available muscle relaxants in terms of rapid onset, short duration, and m

101 bolished in all regions by the smooth muscle relaxants isoproterenol (1 microM), nicardipine (1 micro

102 re incriminated: antibiotics (49.6%), muscle relaxants, latex and anesthetics (15%), nonsteroidal ant

103 l anti-inflammatory drugs or skeletal muscle relaxants (moderate-quality evidence).

104 ing that other nonadrenergic, noncholinergic relaxant neurotransmitters lack influence under baseline

105 maxi-K opener was identified as an effective relaxant of rabbit corporal smooth muscle and shown to b

106 , acetaminophen, opioids, or skeletal muscle relaxants, often in combination.

107 lgesics, antiinflammatory agents, and muscle relaxants) (P< 0.001) and used less physical therapy (0.

108 lock with the reversible, competitive muscle relaxant, pancuronium.

109 Pronounced contractile and relaxant parasympathetic reflex responses could be evoke

110 nse to SCD-associated hypoxia activates CSM "relaxant" pathways; excessive activation of these pathwa

111 Administration of a vascular smooth muscle relaxant prevented onset of myocardial necrosis.

112 oforms is thought to determine smooth muscle-relaxant properties and unique responses to signaling pa

113 play a key role in the anxiolytic and muscle-relaxant properties of benzodiazepine-type drugs; instea

114 NO alters contractile and relaxant properties of the heart.

115 ic technique incorporating a nondepolarizing relaxant provides the best intubating conditions with th

116 significant inverse correlation between ACh relaxant response and 3-NT immunoreactivity.

117 rtrophy (LVH), this endothelium-dependent LV relaxant response is impaired despite a preserved respon

118 In contrast, relaxant response to acetylcholine (ACh) was decreased s

119 modifications of contractile properties and relaxant response to acetylcholine of femoral artery in

120 h) was decreased sixfold without a change in relaxant response to sodium nitroprusside.

121 A similar restoration of relaxant response to substance P was observed in the pre

122 All contractile and relaxant responses evoked by these stimuli were absent i

123 e receptor-mediated positive contractile and relaxant responses in cardiac myocytes.

124 hock exhibited reduced endothelium-dependent relaxant responses in response to acetylcholine.

125 significantly improved endothelium-dependent relaxant responses of aortic rings.

126 to play a significant role in contractile or relaxant responses to any pharmacomechanical or electrom

127 Contractile and relaxant responses to capsaicin and resiniferatoxin were

128 Relaxant responses to EFS were assessed at frequencies f

129 or deferoxamine (500 micromol/L) restored LV relaxant responses to the NO agonists bradykinin (10 nmo

130 survival rates and vascular contractile and relaxant responses were recorded.

131 ted animals showed decreased contractile and relaxant responses, and inosine pretreatment (but not po

132 cells leading to changes in contractile and relaxant responses, proliferation, and the ability of sm

133 dotoxemia and impaired endothelium-dependent relaxant responses, to which MPO-deficient mice were res

134 heir contractility to ACh and impaired their relaxant responsiveness to isoproterenol.

135 sthmatic-like changes in ASM constrictor and relaxant responsiveness, and that these effects were abl

136 proasthmatic changes in ASM constrictor and relaxant responsiveness.

137 Only nondepolarizing muscle relaxants should be used in patients who are at risk for

138 During ambulatory anesthesia, muscle relaxants should be used judiciously because of their im

139 n anesthetics and/or the depolarizing muscle relaxant succinylcholine in malignant hyperthermia-susce

140 by their increased sensitivity to the muscle relaxant succinylcholine.

141 e electron paramagnetic resonance (EPR) spin relaxant techniques.

142 adenylate cyclase and a much more effective relaxant than CGRP.

143 re treated with hydralazine (a smooth muscle relaxant), the blood pressure was normalized but the lun

144 relaxants has improved, the need to combine relaxants to minimize the incidence and severity of thei

145 tion attempts and laryngoscopic view, muscle relaxant use is an independent predictor of complication

146 s and membrane-permeant and -impermeant spin relaxants, we have determined the orientation of C2cPLA2

147 Potent relaxants were evaluated in vivo in a rat model of bladd

148 Dantrolene is a skeletal muscle relaxant which acts by inhibiting intracellular Ca(2+) r

149 Because the muscle relaxant zoxazolamine is a known substrate for CYP1A2, w