ライフサイエンスコーパス: release of

1 n and a neutron n (), resulting in an energy release of 12 MeV.

2 ymatic activity of PARN is necessary for the release of 18S-E from Bystin-associated pre-40S particle

3 However, an accidental or premature release of a gene drive construct to the natural environ

4 aesthetized rats, indicating that exocytotic release of a gliotransmitter within the preBotC contribu

5 he ability of NDs to adsorb and modulate the release of a model drug dexamethasone (Dex) to promote t

6 lows a multistep mechanism, with preliminary release of a number of constraints, possibly through the

7 ticles is demonstrated by comparisons of the release of a signal transducer and model drug by LPS fro

8 ontributes to physiological and pathological release of a variety of small organic molecules, includi

9 ichment in pericentral hepatocytes, membrane release of AA, and generation of proinflammatory eicosan

10 niae As phospholipase A2 (PLA2) promotes the release of AA, we investigated the role of PLA2 in local

11 n and subsequent nucleation of ABS or direct release of ABS aerosols.

12 rent inhibition by enhancing the presynaptic release of acetylcholine.

13 host environment to increase production and release of ACT, strongly suggest that this phenomenon re

14 rimarily expressed in liver facilitating the release of adenosine triphosphate from hepatocytes.

15 steps and instead suggest that the selective release of ADP from a postrigor myosin motor head promot

16 ranulation of mast cells and basophils, with release of agents of the allergic response, ensues when

17 suggested that soil colloids facilitated the release of AgNP (cotransport).

18 In contrast, the release of AITC molecules from all these MOFs was trigge

19 ry system has been fabricated for controlled release of alendronate (AL).

20 down of LRRC8C+LRRC8D strongly inhibited the release of all osmolytes.

21 ema, infiltration, hemorrhage, necrosis, the release of amylase and lipase.

22 zes the lipid bilayer membrane to facilitate release of an encapsulated hydrophilic cargo.

23 ulin, and downstream signaling regulated the release of antibacterial myeloperoxidase and lactoferrin

24 Release of antibiotic from PCL-PVP dosage forms was show

25 the action of a long-acting, slow, effective release of antiretroviral therapy.

26 The trapping and release of Ar is studied combining surface science metho

27 through BK channels, and the production and release of arachidonic acid metabolites.

28 The in vivo release of aroma compounds was affected by the matrix te

29 n commercial pectinase preparations, and the release of aromas from their glycosidic counterparts in

30 No release of As was recorded for Fe(II)-reacted flocs.

31 hicle, it was discovered that the controlled release of autoantigen was important for the suppression

32 ects related to the precise localization and release of BDNF at the synapse have remained obscure.

33 ether, these findings indicate that enhanced release of BDNF through exocytosis caused by activation

34 activity by inhibiting the rate of phosphate release of beta-cardiac myosin-S1, but the molecular mec

35 n and cross-linking on protein breakdown and release of beta-casomorphins was evaluated during in vit

36 at the translocon complex Sec61 mediates the release of beta-DG from the ER membrane, making it acces

37 ormulas can affect protein digestibility and release of bioactive peptides.

38 and Zn-AMSs enhanced maturation and cytokine release of bone marrow dendritic cells in vitro.

39 In vitro release of brimonidine from the GMS drops and gel proper

40 IFN pathway is critical for the GBP-mediated release of Brucella DNA into the cytosol and subsequent

41 Inhibited release of BSA, in both SGF and SIF, was achieved with l

42 Sustained historical releases of BTs within the Mimico Creek watershed have l

43 48 hr of differentiation, corresponding to a release of C/EBPbeta from PARylation-mediated inhibition

44 the preBotC involves P2Y1 receptor-mediated release of Ca(2+) from intracellular stores.

45 They regulate the release of Ca(2+) from organelles, which is important fo

46 pithelial cells, this is achieved by primary release of Ca(2+) from the endoplasmic reticulum via Ca(

47 w that the catalytic 18B7 antibody increases release of capsular polysaccharide from fungal cells.

48 d effects on the balance between storage and release of carbon (C) and associated volatile elements.

49 wed that human saliva strongly decreased the release of carbonyl compounds (aldehydes and ketones).

50 e under near-UV irradiation, led to complete release of carbonyls.

51 s with the plasma membrane, resulting in the release of Cathepsin B.

52 The ZnS shell also slowed release of Cd ions.

53 erns of epitope abundance and the sequential release of cell wall polymers with specific combinations

54 h as transient myocardial ischemia, leads to release of cellular RNA including microRNA(miRNA) into t

55 Conversely, release of charged osmolytes (d-aspartate) was strongly

56 tate often affects neural processing via the release of circulating neurochemicals such as hormones o

57 culating monocytes was achieved by the early release of classical monocytes from bone marrow.

58 In vitro study showed more sustained drug release of CM-AL-containing scaffolds than these of CM/n

59 lant litter decomposition and the subsequent release of CO2 back to the atmosphere.

60 ocean temperature and rainfall on uptake and release of CO2 by the oceans and biosphere.

61 Direct releases of CO2 from litter layer only accounted for 19

62 r redistribution, water loss and qualitative release of compounds were evaluated.

63 e brain vasculature, followed by rupture and release of contents that complete the disruption of the

64 The presence of oxalate alone caused the release of Cr, but not of Fe, from all solid phases.

65 hat the main factor in phytotoxicity was the release of Cu(2+) ions from CuO ENPs after 7 days of exp

66 f lower NEP, it does not promote a metabolic release of current carbon stocks.

67 ters for the detection of apoptosis based on release of cytochrome c from mitochondria in lysates hum

68 d by increased immune cells infiltration and release of cytokines and chemokines in the lungs, which

69 Resolvins counterregulate the release of cytokines/chemokines, including TNFalpha, IL-

70 In contrast, the release of d-[(14) C]aspartate was preferentially sensit

71 ls, while astrocytes enhanced production and release of d-serine.

72 Here we show that Gbetagamma induces the release of DA through DAT.

73 of the PEDF-receptor (PEDF-R) leading to the release of DHA; this free DHA led to enhanced docosanoid

74 the degree of tissue disintegration, and the release of dimethyl sulfide and dimethyl disulfide was r

75 Light increased their dissolution and release of dissolved Cd.

76 y through improved protection and controlled release of DNA cargo.

77 explosive cell lysis or cell death, and the release of DNA is confined to a discrete subpolar locati

78 opo II activity was detected via the numeric release of DNA nano-circles, which were visualized at th

79 The release of dopamine (DA) regulates rewarding behavior an

80 Moreover, no release of dopamine was observed, ruling out amphetamine

81 Irk channels as a requirement for regulated release of Dpp, highlighting the importance of the tempo

82 We hypothesize that the local release of drug into the tumor vasculature and resulting

83 e received much attention for the controlled release of drugs due to the remarkable ability of CB7 to

84 TMUPS), using coated pellets, for controlled release of drugs is an effective therapeutic alternative

85 the formation of binary asteroids and to the release of dust, both directly and, in some cases, throu

86 with a concomitant phosphorylation of Rb and release of E2F1.The histone methyltransferase EZH2 silen

87 queous phase showed a high stability and low release of encapsulated compounds over time.

88 visceral organs, which is likely due to the release of endogenous opioids.

89 dministration of OT does not lead to central release of endogenous OT.

90 e has been renewed interest in environmental releases of engineered gene drives due to recent proof o

91 Our model, nanoRelease, estimates the annual releases of ENMs from manufacturing, use, and disposal o

92 e water quality by causing the incorporation/release of environmental contaminants and biological nut

93 e eosinophil surface markers, as well as the release of eosinophil peroxidase by eosinophils in the b

94 An all-or-none step led to final release of ESCRT-III and Vps4.

95 eve electrochemically controlled capture and release of ethylene in the solid state.

96 ction to facilitate efficient production and release of eVP40 VLPs.

97 Nitrate induces the release of exercise/PGC1alpha-dependent myokine FNDC5/ir

98 mal inflammatory responses by triggering the release of exosomes containing unshielded RNAs that acti

99 Release of exosomes is affected by differentiation of co

100 To address this, we imaged the release of FM1-43, a dye that is incorporated into synap

101 17) show that autophagy is necessary for the release of free fatty acids from intracellular stores wi

102 icient movement together with the continuous release of fresh class-enzyme leads to a greatly acceler

103 offshore northern Sumatra, revealing recent release of fresh water within the deep sediments.

104 but alleviate pain and itch through synaptic release of GABA.

105 upon receptor activation but is prompted by release of GCL from the nuclear envelope during mitosis.

106 wed biphasic NU7441 release and pH-dependent release of gemcitabine.

107 cotransporters can induce Ca(2+) influx and release of GLP-1 as a result of electrical activity, whi

108 blockers were reported to reduce spontaneous release of glutamate and it was proposed that there was

109 bination of failed clearance and exaggerated release of glutamate by glial cells during immune activa

110 We further show that the endogenous release of glutamate from the inner hair cells may incre

111 e (rice PNGase Ar) and show that both enable release of glycans with more sugar residues on the proxi

112 oendocrine circuit that evokes the pulsatile release of gonadotropin hormones (luteinizing hormone an

113 of ovarian 17beta-estradiol (E2) regulating release of gonadotropin releasing hormone (GnRH) and lut

114 white dwarf, producing bursts powered by the release of gravitational potential energy.

115 roquinoline/indoline derivatives in toluene (release of H2) at 130 degrees C.

116 d ursodeoxycholic acid on the expression and release of HbetaD1 and HbetaD2 from colonic epithelial c

117 IP code data, and time from candy testing to release of health alerts for lead-contaminated candies f

118 to describe the generation, consumption and release of heat from landfills, to predict landfill temp

119 nalization of CD63 and CD203c as well as the release of histamine, IL-4 and IL-13.

120 HMC-1 cells responded to fungal antigens by release of histamine.

121 report a significant correlation between the release of host double-stranded DNA (dsDNA) following rh

122 effects of potential subsurface and surface releases of hydrocarbons on the wells.

123 isolated renal macrophages showed increased release of IL-10, whereas tumor necrosis factor and cath

124 membrane disruption, which allows efficient release of IL-1beta independently of the recently descri

125 he NLRP3 inflammasome and the maturation and release of IL-1beta, a response that is absent in SMG ce

126 exposure with receptor agonists induced the release of IL-33 and subsequent eosinophil infiltration

127 , hepatic ILC2s are poised to respond to the release of IL-33 upon liver tissue damage through expres

128 gen exposure through several steps including release of IL-33, which promotes cytokine (IL-5, IL-13)

129 ition, the suppression of TLR1 inhibited the release of IL-33.

130 MCs were permissive for HRV replication and release of infectious HRV particles.

131 is able to additionally induce increased CF release of inflammatory and pro-fibrotic cytokines and m

132 ion of pro-inflammatory monocyte subsets and release of inflammatory mediators.

133 by acting on myeloid cells and promoting the release of inflammatory molecules, including IL-1beta.

134 anced excitatory and inhibitory engrams, the release of innate responses and recall of associative me

135 re associated with the hydrolysis of ATP and release of inorganic phosphate (Pi) from the nucleotide

136 setting of hyperglycemia, resulting in fast release of insulin and subsequent drop of BG level in vi

137 An in vivo pilot study showed a prolonged release of insulin from swellable MN patches, leading to

138 which is cytolysis, which is associated with release of intact granules, so-called clusters of free e

139 g human infection were assessed by measuring release of interleukin 8 from AGS cells (to detect cag p

140 ntly respire nitrate without the significant release of intermediates, such as nitrous oxide.

141 We report here the release of IslandViewer 4, with novel features to accomm

142 4 induces its intramembrane cleavage and the release of its cytosolic intracellular domain (CD74-ICD)

143 e 3 resulted in the destruction of 1 and the release of its guest.

144 xpression of FBXO17 inhibits agonist-induced release of keratinocyte-derived cytokine (KC) and interl

145 ic actin is an important factor limiting the release of large lytic granules from NK cells from patie

146 ponse, new methods involving the rearing and releasing of large numbers of mosquitoes to eliminate or

147 dition, IL-6-type cytokines may increase the release of leptin from adipocytes and by those means ind

148 anoemulsions in filled hydrogels reduces the release of limonene.

149 The stability and release of loaded crocin, safranal, and picrocrocin in m

150 The pulsatile release of luteinizing hormone (LH) is critical for mamm

151 The release of mature IL-1beta depends on 2 regulated events

152 r signalling and PI3K-AKT-mTOR axis leads to release of MCL cells from TME, reversal of drug resistan

153 n particles deposited on a filter before the release of MEA.

154 le geometries for the controlled loading and release of medicines is presented.

155 deoxyHbS anchoring to the membrane, induces release of membrane-bound glycolytic enzymes and in turn

156 of top predator ranges could promote further release of mesopredator populations, altering ecosystem

157 rt a function of the nutrient processing and release of metabolites.

158 Biogenic production and release of methane (CH4 ) from thawing permafrost has th

159 ements suggest that large future atmospheric releases of methane from old carbon sources are unlikely

160 plasma (n=6) and control plasma (n=6) on the release of microvesicles from glomerular endothelial cel

161 We suggest that upregulation and release of miR-21 contribute to sensory neuron-macrophag

162 are removed from axons triggered by the bulk release of mitochondrial anchoring protein syntaphilin v

163 cytosolic DNA in infected cells through the release of mitochondrial DNA (mtDNA) to drive the produc

164 duced mitochondrial respiratory capacity and release of mitochondrial DNA into the cytosol.

165 iggering mitochondrial hyperpolarization and release of mitochondrial superoxide which, after convers

166 allele (Ile62 in factor H) led to decreased release of MMP-8 from neutrophils compared with the majo

167 d landscapes; and (g) deliberate culture and release of monarchs and invasive milkweeds.

168 er these factors act primarily to effect the release of mRNA and tRNA from the ribosome, with the spl

169 As an example, we simulated ten years of release of nano CeO2, CuO, TiO2, and ZnO in the San Fran

170 oir layers are intended to promote prolonged release of nanoparticles into the submucosal tissue.

171 Release of naringin was faster at pH 5.5 to 6.5, and via

172 core vesicles (LDCVs) mediate the regulated release of neuropeptides and peptide hormones.

173 TS: Synaptic transmission is mediated by the release of neurotransmitters from synaptic vesicles in r

174 The release of neutrophil extracellular traps (NETs [NETosis

175 ADAM10 inhibitors prevent the release of NLGN3 into the tumour microenvironment and ro

176 lectrode was further utilized to monitor the release of NO from different cells, realizing a signific

177 ic bodies, necrotic debris, exosomes or even release of non-vesicular antigen from infected cells.

178 evels of IRGM and necroptosis, and increased release of nuclear DAMPs compared with controls.

179 vered that IkappaBalpha enhances the rate of release of nuclear factor kappa B (NFkappaB) from DNA ta

180 te of inflammation, driven by local platelet release of nucleotide-sugar donors.

181 Plant growth promotion was explained by slow release of nutrients, although a mechanistic understandi

182 The pattern of release of oil from the microcapsules and co-microcapsul

183 studied in terms of survival of L. casei and release of oil in sequential exposure to simulated saliv

184 e by steady-state analyses claiming that the release of one cationic species as product requires the

185 g animals in open-exchange cages permits the release of organic wastes, some of which ultimately reac

186 Recently, inhibition of the release of oxidized fatty acyl chains from CL by the cal

187 ntinued to act as regulators restricting the release of oxygen from CaO2 cores.

188 This shows that CDK9 stimulates release of paused polymerase and activates transcription

189 The release of paused RNA polymerase II into productive elon

190 nes increased unwrapping, whereas inhibiting release of paused RNAPII or reducing RNAPII elongation d

191 transcriptional enhancers might modulate the release of paused RNAPII via 3D chromatin looping.

192 The release of pentane and 2-ethylfuran was related to the d

193 Ability to control the release of peptide resulted in both higher and prolonged

194 National release of PFASs was estimated by coupling measured conc

195 t the febrile response is dependent on local release of PGE2 onto its target neurons and not on the o

196 The assay detects the release of phenylalanine amino acid in a reaction with t

197 e activities that may be caused by a limited release of PhIP molecules from the particulate PhIP.

198 Release of phosphate after phytate degradation and its a

199 econd phase of the biphasic force decay upon release of phosphate from caged phosphate was previously

200 MoFe protein and Fe protein dissociation to release of Pi Because the Fe protein cannot interact wit

201 includes electron transfer, ATP hydrolysis, release of Pi, and dissociation of the oxidized, MgADP-b

202 ndrome preeclampsia (PE), there is increased release of placental syncytiotrophoblast extracellular v

203 The release of pollutants from such particles depends on mas

204 hrome P450 (CYP) 1A1 to obtain the selective release of potent anticancer products within cancer tiss

205 d significantly lower metabolic activity and release of pro-inflammatory cytokines than CFC tissue, b

206 We also tested release of profibrinolytic enzymes, urokinase, and tissu

207 idoglycan (PG), pose a major problem for the release of progeny virions.

208 ak of inflammation, accompanied by a massive release of proinflammatory cytokines at the maternal-fet

209 4) in macrophages results in the coordinated release of proinflammatory cytokines, followed by regula

210 isplayed significantly higher expression and release of proinflammatory cytokines, such as chemokine

211 different signaling pathways leading to the release of proinflammatory cytokines.

212 The resulting hydrogel provides sustained-release of protein for more than a week.

213 The in vitro release of protein from the beads in simulated gastric f

214 ble polymeric microspheres for the sustained release of proteinaceous drugs.

215 It is thought that the release of pyrophosphate (PPi) triggers reverse conforma

216 optimal medical treatment, and the increased release of ROS from cardiac mitochondria and other sourc

217 d surface expression of BCMA and reduced the release of sBCMA by pDCs.

218 rs enhanced evolvability, resulting from the release of selective constraint on somatic gene networks

219 Anthropogenic activities resulting in releases of selenium-laden waste streams threaten freshw

220 We found that oxytocin provokes the release of serotonin, which in turn impacts on the serot

221 tes pupal ecdysis, is governed by the serial release of several key factors, which act both somatical

222 DNA methylation are not sufficient to cause release of silencing.

223 ned, processively copied, and regenerated by release of single-stranded product DNA.

224 erization of azobenzene, thus leading to the release of siRNA due to unmatched host-guest pairs.

225 the surface of human pDCs was accompanied by release of soluble BCMA (sBCMA); inhibition of gamma-sec

226 sure of these cells to allergens induces the release of soluble mediators causing allergic symptoms.

227 were able to affect cell viability, and the release of soluble molecules (free amino acids, proteins

228 ontrol peroxisome membrane integrity and the release of soluble peroxisomal matrix proteins.

229 he observed effect is most likely due to the release of TF-bearing EVs of different dimensions, which

230 on biologically relevant for force-dependent release of TGF-beta from latency.

231 y, in vivo tissue distribution, and rates of release of the active constituents after binding to bone

232 aperitoneal administration enabled triggered release of the active MMAE toxin to inhibit tumor growth

233 Glypican 4 induces release of the AMPA receptor clustering factor neuronal

234 Early steps in infection include release of the capsid into the cytoplasm, docking of the

235 hat I2 is required for virion morphogenesis, release of the D13 scaffold, and the association of EFC

236 Since the first release of the database in 2003, IPD-MHC has grown and c

237 m limitations including instability, a burst release of the drug, and limited surface functionalizati

238 has been difficult to study due to the rapid release of the genome once the capsid interacts with the

239 ein ion channel involved in the assembly and release of the hepatitis C virus, was determined from pr

240 The current release of the human genome, GRCh38, contains 146 putati

241 hey are activated in cancer cells, involving release of the I(-) ligand in the presence of glutathion

242 etion of IL-22 and ICOSL/TNF-alpha-dependent release of the IL-22 inducible antimicrobial protein cal

243 the first domain is a rate limiting step for release of the inactivation domain, and highlights the f

244 t the target compound ee and the synchronous release of the indicator results in a nonenantioselectiv

245 Since the release of the Institute of Medicine report: From cancer

246 Inhibiting the formation and release of the invaginations strongly interfered with bl

247 Our findings revealed a pH-dependent release of the ligand associated with a conformational c

248 Gase F and A release may be insufficient for release of the more highly core-modified N-glycans, espe

249 that couples the transport-associated inward release of the Na(+) ion from the Na2 site to intracellu

250 suggesting that these channels decrease the release of the neurotransmitter, glutamate.

251 y the referring specialists before and after release of the PET results.

252 Block of THIK-1 function also inhibits release of the pro-inflammatory cytokine interleukin-1be

253 LPS-induced release of the proinflammatory marker tumor necrosis fac

254 ined, more reliable data set, based on a new release of the ProNIT database, which has significantly

255 the intermembrane space likely involves the release of the protein precursor within the lipid bilaye

256 molecules at the membrane and the continuous release of the proteins from the vesicle to the plasma m

257 d in the UK-Ireland group of the most recent release of the Psychiatric Genomics Consortium (PGC), th

258 -binding site, respectively, suggesting that release of the Q toward the membrane is coupled to an en

259 okines IL-6 and IL-12p40 while enhancing the release of the regulatory/anti-inflammatory cytokine IL-

260 es for a range of applications, with in situ release of the required hydrogen from a stable liquid of

261 ry substrate in the active-site triggers the release of the solvent-derived ligand, priming the metal

262 their viscoelastic relaxation response upon release of the stretching force.

263 eorganization with permeability increase and release of the TFD from the nanoplexes are the main fact

264 lation involving the growth hormone-mediated release of the transcriptional blockade of genes associa

265 F-alpha converting enzyme (TACE) proteolytic release of the transmembrane TNF (tmTNF) ectodomain.

266 4 detected annihilation events from a single release of the trapped anti-atoms accumulated from five

267 downregulation of LRRC8D strongly inhibited release of the uncharged osmolytes [(3) H]taurine and my

268 docking of the capsid at a nuclear pore, and release of the viral genome into the nucleus.

269 the capsid engages the NPC and what triggers release of the viral genome into the nucleus.

270 and will be regularly updated following new releases of the NCBI RefSeq database.

271 that facilitate the localized and sustained release of therapeutics.

272 terials for the controlled encapsulation and release of therapeutics.

273 ferent, locally confined effects, namely the release of thermal energy from the polymer surface and t

274 The release of these nanoparticles into the solution was con

275 liver cells, resulting in the formation and release of thousands of invasive merozoites into the blo

276 ed contraction can be explained by a greater release of thromboxane from PVAT from female animals and

277 of IL-1beta on house dust mite (HDM)-induced release of thymic stromal lymphopoietin and GM-CSF from

278 l2 interacting protein, revealed an enhanced release of TNF in the absence of Fhl2.

279 o T. gondii infection, without affecting the release of TNF-alpha, and indicated a role for the infla

280 ic arthritis by impeding the Adam17-mediated release of TNF.

281 We show that prefolded BamA promotes the release of tOmpA from Skp despite the nM affinity of the

282 Blood-brain barrier disruption (BBB) and release of toxic blood molecules into the brain contribu

283 undesirable transformation products, and the release of toxic metals, heat-activated persulfate may b

284 Release of Tr-A from both formulations was greatly accel

285 The in vivo release of Tr-A from microspheres made of a higher molec

286 y pulsed electric field showed a significant release of trans-(4.01+/-0.48) and cis-(5.04+/-0.26mug/g

287 cific degradation of the outer ZN matrix and release of transfection competent CS/DNA NPs occurred in

288 ted protein kinase (p38 MAPK) activation and release of tumor necrosis factor-alpha (TNF-alpha).

289 opolysaccharide (LPS)-induced human monocyte release of tumor necrosis factor-alpha (TNFalpha) was as

290 Here, we demonstrate near-IR light-triggered release of two drug molecules from both DNA-based and pr

291 gurations is used to explore the capture and release of two guest molecules, dextromethorphan and bet

292 e induction of IFN-responsive genes, and the release of type I IFN from transfected cells.

293 rimary trophoblasts through the constitutive release of type III IFNs (IFNlambda1 and IFNlambda2) and

294 The first release of UK Biobank imaging data comprised participant

295 an appropriate level of polarity for timely release of vancomycin, (iii) Eudragit E100 (a copolymer

296 The release of VEGF could be sustained for 4weeks.

297 ope with a cellular membrane is required for release of viral genomic material, so the virus can ulti

298 ery systems for encapsulation and controlled release of volatile allyl isothiocyanate (AITC) molecule

299 The release of volatiles followed mostly the van't Hoff prin

300 Release of zinc during peptic digestion was lower for WP