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1 mone 44 (DH44), an ortholog of corticotropin-releasing factor.
2 alize with the stress hormone, corticotropin releasing factor.
3 y active clinical candidate of corticotropin-releasing factor 1 (CRF 1) antagonist 1 showed a signifi
5 de), D2R agonist (quinpirole), corticotropin-releasing factor 1 (CRF1) antagonist (antalarmin), and a
6 ne domains of the glucagon and corticotropin releasing factor 1 (CRF1) receptors to develop improved
9 n of Ras protein-specific guanine nucleotide releasing factor 1 (RasGrf1), a Ras activator (5-fold, P
10 with Ras protein-specific guanine nucleotide-releasing factor 1 (RASGRF1), leading to impaired activa
11 armacologic inhibition (with a corticotropin-releasing factor 1 receptor antagonist) of pain-related
12 earlier lead pyrazinone-based corticotropin-releasing factor-1 (CRF(1)) receptor antagonist, reveale
13 al-like state characterized by corticotropin-releasing factor-1 (CRF(1)) receptor antagonist-reversib
16 s to palatable food results in corticotropin-releasing factor-1 (CRF1) receptor antagonist-reversible
17 26907 in the ras-specific guanine-nucleotide releasing factor 2 (RASGRF2) gene, encoding a protein th
19 ene (Ras protein-specific guanine nucleotide-releasing factor 2) with all clinical events except stro
23 ess neurotransmitters, such as corticotropin-releasing factor and dynorphin, in the neurocircuitry of
24 ing by increased expression of corticotropin-releasing factor and its feedback regulation of TLR4 exp
25 and Hcrt systems in which the corticotropin-releasing factor and N/OFQ systems coordinately modulate
27 (especially neuropeptide Y and corticotropin-releasing factor) are modulated by alcohol drinking duri
30 ed Crk SH3 domain-binding guanine-nucleotide releasing factor (C3G) binding to CrkII, whereas inhibit
32 othalamus and primarily in non-corticotropin releasing factor-containing neurons of the bed nucleus o
33 os activation were observed in corticotropin releasing factor-containing neurons of the paraventricul
34 at baseline and in response to corticotropin-releasing factor (CRF) (0.5 microg kg(1)) plus arginine
36 s, including a coordination of corticotropin-releasing factor (CRF) actions at both of its receptors,
38 also posit a central role for corticotrophin-releasing factor (CRF) and an interaction between CRF an
39 tine SA on the coexpression of corticotropin-releasing factor (CRF) and arginine vasopressin (AVP) mR
40 gh it has long been known that corticotropin-releasing factor (CRF) and CRF receptors are prominent i
41 esent review is on the role of corticotropin-releasing factor (CRF) and CRF-related peptides in the d
42 ng-term alterations in central corticotropin-releasing factor (CRF) and glucocorticoid receptor (GR)
43 ion between the stress hormone corticotropin releasing factor (CRF) and glutamate release onto dopami
44 d to partially colocalize with corticotropin-releasing factor (CRF) and growth hormone-releasing horm
45 xtrahypothalamic expression of corticotropin-releasing factor (CRF) and its G-protein-coupled CRF1 an
48 europharmacological actions of corticotropin-releasing factor (CRF) and norepinephrine in extrahypoth
49 Release of the neuropeptides corticotropin-releasing factor (CRF) and orexin-A in the ventral tegme
53 e report the identification of corticotropin-releasing factor (CRF) as a critical component of the ca
55 ne arm of the stress response, corticotropin-releasing factor (CRF) can act in the brain to modulate
56 ase of neuromodulators such as corticotropin-releasing factor (CRF) can drive drug-dependent behavior
59 e stress-related neuropeptide, corticotropin-releasing factor (CRF) directs this by a bimodal regulat
60 the central extrahypothalamic corticotropin-releasing factor (CRF) expression is associated with str
64 enced by the highly conserved corticotrophin-releasing factor (CRF) family of peptides and receptors
66 tin 3 (Ucn 3), a member of the corticotropin-releasing factor (CRF) family of peptides, is strongly e
67 tin 2 (Ucn2), a peptide of the corticotropin-releasing factor (CRF) family, binds with high affinity
68 n of the stress neuromediator, corticotropin-releasing factor (CRF) has been implicated in these diso
69 levant PI cells identified the corticotropin-releasing factor (CRF) homolog, DH44, as a circadian out
70 e self-administration, reduced corticotropin-releasing factor (CRF) immunodensity in the paraventricu
71 ence of somatostatin (SS) and corticotrophin-releasing factor (CRF) in forebrain neurons that project
72 lation of cytosolic calcium by corticotropin-releasing factor (CRF) in midbrain dopamine neurons.
73 k indicates a crucial role for corticotropin-releasing factor (CRF) in neurobiological responses asso
74 support a modulatory role for corticotropin-releasing factor (CRF) in regulating the dorsal raphe nu
75 ole of the stress neurohormone corticotropin-releasing factor (CRF) in stress-induced binge eating in
76 work hypothesizing a role for corticotropin-releasing factor (CRF) in the IC during craving and rela
77 tionship between dynorphin and corticotropin-releasing factor (CRF) in the induction of dysphoria, th
82 d that the stress neurohormone corticotropin-releasing factor (CRF) inhibits 5-HT neurons in the dors
83 ggests that catecholamines and corticotropin-releasing factor (CRF) interact in a serial manner to ac
84 ces the release of the peptide corticotropin-releasing factor (CRF) into the ventral tegmental area (
90 emonstrate that, in the vBNST, corticotropin releasing factor (CRF) is expressed in neurons that inne
95 t experiments examined whether corticotropin-releasing factor (CRF) modulates memory consolidation vi
97 5, we measured AT(1) receptors corticotropin-releasing factor (CRF) mRNA and immunoreactive CRF in th
101 on, potentially by activating corticotrophin releasing factor (CRF) neurons in the anterolateral cell
102 d activates a subpopulation of corticotropin-releasing factor (CRF) neurons in the bed nucleus of the
103 pecifically recruited GABA and corticotropin-releasing factor (CRF) neurons in the mPFC and produced
104 hip between corticosterone and corticotropin-releasing factor (CRF) on both beta-amyloid (Abeta) and
105 of an intravenous injection of corticotropin-releasing factor (CRF) on fructose malabsorption and the
106 was to examine the ability of corticotropin releasing factor (CRF) or antibody to insulin growth fac
108 , arginine-vasopressin (AVP), corticotrophin-releasing factor (CRF) or tyrosine hydroxylase (TH).
114 derable evidence suggests that corticotropin-releasing factor (CRF) plays an important role in regula
116 eta elevation are dependent on corticotropin-releasing factor (CRF) receptor 1 signaling and an intac
119 awal was mediated by increased corticotropin releasing factor (CRF) receptor-1 expression and signall
122 Natural peptide agonists of corticotrophin-releasing factor (CRF) receptors bind to the receptor by
123 lation increases the levels of corticotropin-releasing factor (CRF) receptors in the serotonergic dor
126 e stress-related neuropeptide, corticotropin-releasing factor (CRF) regulates the dorsal raphe nucleu
127 e through alterations in brain corticotropin-releasing factor (CRF) regulation of neurocircuitry invo
130 Over the past few decades, corticotropin-releasing factor (CRF) signaling pathways have been show
132 nforcement is a recruitment of corticotropin-releasing factor (CRF) signaling within the amygdala.
133 dies have implicated the brain corticotropin-releasing factor (CRF) stress systems in mediating the n
134 VN) have been shown to inhibit corticotropin releasing factor (CRF) synthesis via GABA(A) receptors.
135 trahypothalamic stress peptide corticotropin-releasing factor (CRF) system and activation of CRF(1) r
136 H secretion by activating the corticotrophin-releasing factor (CRF) system and sympathoadrenal pathwa
141 ncluding the extrahypothalamic corticotropin-releasing factor (CRF) system, following long-term drug
143 gdala (Neo-A) lesions on brain corticotropin-releasing factor (CRF) systems and hypothalamic-pituitar
146 gdala (CeA), ethanol acts via corticotrophin-releasing factor (CRF) type 1 receptors to enhance GABA
151 e number of neurons expressing corticotropin releasing factor (CRF), a neuropeptide that has a promin
152 imolecular interaction between corticotropin-releasing factor (CRF), a neuropeptide, and its type 1 r
153 ited different sensitivity to corticotrophin-releasing factor (CRF), a stress hormone that has been i
154 this, the CEA highly expresses corticotropin-releasing factor (CRF), an important modulator of stress
155 excitatory amino acids (EAAs), corticotropin-releasing factor (CRF), and endogenous opioids acting at
157 regional, CCK-8, substance P, corticotropin releasing factor (CRF), and neuropeptide Y levels in adu
158 r modulation by dopamine (DA), corticotropin-releasing factor (CRF), and their combination (DA plus C
159 The neuroactive substances corticotropin-releasing factor (CRF), arginine-vasopressin (AVP), hist
160 is thought to communicate via corticotropin-releasing factor (CRF), but studies have yet to examine
164 ed receptor B1 family includes corticotropin-releasing factor (CRF), growth hormone-releasing hormone
165 axis-activating neuropeptide, corticotropin-releasing factor (CRF), may be the keystone in drug-indu
166 nd measured mRNA expression of corticotropin releasing factor (CRF), neuropeptide Y (NPY) and proopio
167 es indicate the involvement of corticotropin-releasing factor (CRF), noradrenaline, dopamine, glutama
170 e focus is on the receptor for corticotropin-releasing factor (CRF), the orchestrator of the stress r
172 oradrenergic substrates [via a corticotropin-releasing factor (CRF)-dependent mechanism] that regulat
173 nd inhibitory transmission in corticotrophin-releasing factor (CRF)-expressing dorsal-medial (mpd) ne
174 en shown previously to cause a corticotropin-releasing factor (CRF)-mediated increase in tonic locus
190 nal aggression) is impaired by corticotropin-releasing factor-(CRF) related peptides, but where these
191 density, stress neuropeptide (corticotropin releasing factor--CRF) levels, and plasma corticosterone
192 tested the hypothesis that the corticotropin-releasing factor (CRF1) antagonist GSK561679 differentia
193 ticoliberin family include the corticotropin releasing factors (CRFs), sauvagine, the urotensins, and
195 region-specific alterations of corticotropin-releasing factor expression and promoter methylation, ch
196 neuropeptides vasopressin and corticotropin-releasing factor facilitate, while serotonin inhibits, a
197 rs, which bind peptides of the corticotropin releasing factor family and are key mediators in the str
199 ently identified member of the corticotropin-releasing factor family, is expressed in discrete neuroe
203 al. provide a causal link between histamine-releasing factor (HRF) interactions with IgE and food al
206 ther suggest that an activated corticotropin-releasing factor/hypothalamic-pituitary-adrenal axis sys
207 thropin-releasing hormone, and corticotropin-releasing factor immunoreactive cells in the paraventric
208 s the physiological actions of corticotropin-releasing factor in the anterior pituitary gland and the
210 A1 and aromatase enhanced local bone marrow-releasing factors, including androgen receptor, estrogen
216 s in restraint-induced Fos and corticotropin-releasing factor mRNA expression in the neurosecretory r
217 cting to vasopressinergic and corticotrophin releasing factor neurons in the paraventricular nucleus,
218 acts with the neuromodulators, corticotropin-releasing factor, norepinephrine, dopamine, and serotoni
219 role of brain stress systems (corticotropin-releasing factor, norepinephrine, orexin [hypocretin], v
220 l impact of treatment with such hypothalamic releasing factors on recovery from critical illness as w
221 lockade of the stress hormone corticotrophin-releasing factor or of peripheral GC action, as well as
222 ior hypothalamus that may gate corticotropin-releasing factor output from the amygdala to the anterio
223 n of the brain stress system's corticotropin-releasing factor outside of the hypothalamus in the exte
225 this region of receptors for corticotrophin-releasing factor, pituitary adenylate cyclase-activating
226 appetite regulation, including corticotropin releasing factor, pro-opiomelanocortin B, and glucose tr
229 ed differential involvement of corticotropin-releasing factor receptor (CRFR) 1 and 2 in acute stress
231 dministration of the selective corticotropin-releasing factor receptor 1 (CRF(1)) antagonist R121919
232 n, we examined the role of the corticotropin-releasing factor receptor 1 (CRF(1)) in this behavior as
233 haracterize the effects of the corticotropin-releasing factor receptor 1 (CRF-R1) antagonist, GW87600
234 (NE) receptors (alpha1) via a corticotropin-releasing factor receptor 1 (CRF-R1)-dependent mechanism
235 g the efficacy of GSK561679, a corticotropin-releasing factor receptor 1 (CRF1 receptor) antagonist i
240 what has been observed for the corticotropin-releasing factor receptor 1 (CRFR1), SAP97 expression is
241 r-activated receptor gamma and corticotropin-releasing factor receptor 1 were notable exceptions.
242 ivated by either neurokinin I, corticotropin-releasing factor receptor 1, or dopamine D(1) receptors.
244 ed significant upregulation of corticotropin releasing factor receptor 2 (CrfR2) in the amygdala of m
246 ent study examines the role of corticotropin releasing factor receptor subtypes 1 and 2 (CRFR1, CRFR2
247 CRF(2(a))R and the homologous corticotropin-releasing factor receptor type 1 (CRF(1)R) possessing a
248 vestigated whether blockade of corticotropin-releasing factor receptor type 1 (CRF-R1) could prevent
249 ctions in anandamide driven by corticotropin-releasing factor receptor type 1 (CRF1) potentiation of
250 re the interaction between the corticotropin releasing factor receptor type 1 (CRF1R) and its native
251 ed interactions of the class B corticotropin-releasing factor receptor type 1 (CRF1R) with two peptid
253 compartments, we show that the corticotropin-releasing factor receptor type 1 has a specific monomer/
254 nsmembrane domain of the human corticotropin-releasing factor receptor type 1 in complex with the sma
258 central stress response, while corticotropin-releasing factor receptor type 2 (CRFR2) has been sugges
259 bserved abnormal expression of corticotropin-releasing factor receptor type 2 (CRFR2) to be associate
262 pyrazolo[1,5-a]-1,3,5-triazine corticotropin releasing factor receptor-1 (CRF(1)) receptor antagonist
263 pyrazolo[1,5-a]-1,3,5-triazine corticotropin releasing factor receptor-1 (CRF(1)) receptor antagonist
264 is unaffected by alpha1-AR and corticotropin-releasing factor receptor-1 (CRFR(1)) antagonists, but i
265 tention were attenuated by the corticotropin-releasing factor receptor-1 antagonist antalarmin but no
266 application of urocortin I (a corticotrophin-releasing factor receptor-2 agonist) to the ventromedial
271 Urocortin 3 (Ucn 3) is a corticotrophin-releasing factor related neuropeptide highly expressed i
272 he peptide antagonist, cyclic corticotrophin-releasing factor residues 30-41 (cCRF(30-41)), was calcu
273 ion-like protein (RepA-WH1) into the E. coli releasing factor RF1 promotes its aggregation and enable
275 n-gamma (IFN-gamma) and induce cytolysis via releasing factors such as perforin, which permeabilizes
276 s), (4) the (gastrointestinal) corticotropin-releasing factor system, and (5) the intestinal response
279 These results reveal PAR polymer as an AIF-releasing factor that plays important roles in PARP-1-de
280 s circadian rhythms of locomotor behavior by releasing factors that act on receptor sites near the th
281 uscle laceration sites on a delivery vehicle releasing factors that induce cell activation and migrat
282 role in maintaining vascular homeostasis by releasing factors that regulate local blood flow, system
283 counteracting the functions of corticotropin-releasing factor, the primary stress-mediating neuropept
284 lin, nesfatin-1, somatostatin, corticotropin-releasing factor, thyrotropin-releasing hormone and calc
285 buting ions, removing neurotransmitters, and releasing factors to influence blood flow and neuronal a
286 ation between histamine release to histamine releasing factor/translationally controlled tumor protei
287 hesis was investigated for the corticotropin-releasing factor type 1 (CRF(1)) receptor using a novel
290 ve effect is mediated via the corticotrophin-releasing factor type 1 receptor (CRF1R, also known as C
291 peated social stress decreased corticotropin-releasing factor type 1 receptor and increased mu-opioid
293 LTCC-based mechanism; instead, corticotropin-releasing factor type 1 receptors (CRF1s) mediate alcoho
294 LTCC-based mechanism; instead, corticotropin-releasing factor type 1 receptors (CRF1s) mediate alcoho
295 o central anorectic effects of corticotropin-releasing factor type 2 (CRF(2)) receptor stimulation.
297 hat the mechanism involved the corticotropin-releasing factor type 2 receptor, cAMP elevation, and ac
299 ombined administration of those hypothalamic releasing factors, which have been identified as suppres
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