ライフサイエンスコーパス: relentless

1 renal function, persistent proteinuria, and relentless accumulation of extracellular matrix leading

2 Amyotrophic lateral sclerosis is a relentless and devastating adult-onset neurodegenerative

3 separated driver mutations, coupled with the relentless and heterogeneous nature of the genome instab

4 nd health care professionals struggle with a relentless and irreversible neurological syndrome that c

5 Clinical progression was relentless and many children died in infancy.

6 ng in adulthood, tumor progression is rapid, relentless, and ultimately leads to the patient's death

7 To counteract this relentless assault, cells have developed multiple pathwa

8 There is no better example of a relentless attack on evidence-based biomedical research

9 state of cellular amnesia, not only inducing relentless cellular proliferation, but also bypassing ch

10 This increase parallels the relentless clinical progression seen in these disorders.

11 We suggest that this relentless competition drives positive selection, promot

12 Treatments that slow its relentless course are not yet available, and biomarkers

13 utic approaches are available that alter the relentless course of AD or other dementias of aging.

14 atric symptoms, weight loss, dementia, and a relentless course with death about 20 years after diseas

15 atric symptoms, weight loss, dementia, and a relentless course with death about 20 years after diseas

16 Organisms are adapted to the relentless cycles of day and night, because they evolved

17 lethal disease that is characterized by the relentless death of motoneurons.

18 The relentless decline in beta-cell function frequently obse

19 lation of fibroblasts and myofibroblasts and relentless deposition of extracellular matrix (ECM).

20 cemia, consequent chronic hyperglycemia, and relentless deterioration of beta-cell function.

21 Here, we show that rapid and relentless dilution of surface water chemistry is occurr

22 The relentless discovery of cancer biomarkers demands improv

23 h T2DM is traditionally viewed as a chronic, relentless disease in which delay of end-organ complicat

24 spread that may represent the mechanism for relentless disease progression.

25 nderstanding of this molecule because of the relentless efforts of multiple investigators who have di

26 sometimes develop increasingly frequent and relentless episodes of devastating generalized dystonia

27 ration of traits for attack and defense, but relentless escalation of these arms races does not neces

28 Therapy to slow the relentless expansion of interstitial extracellular matri

29 The relentless expansion that threatens the sustainability o

30 e face of unyielding mortality rates and the relentless expense of end-stage renal disease, governmen

31 osing panencephalitis (SSPE), a progressive, relentless fatal disorder.

32 firm that inter-core XT distortions are more relentless for cores fabricated around the central axis

33 from a well-characterized, early-onset, and relentless form of photoreceptor cell degeneration.

34 As of this writing, the relentless growth in computational power, the developmen

35 Trypanosoma brucei faces relentless immune attack in the mammalian bloodstream, w

36 Relentless increases in the size and performance of mult

37 The natural history of AMD demonstrates relentless loss of vision in persons who developed advan

38 These cancers exhibit a relentless malignant progression characterized by widesp

39 The relentless nature of treatment was also a burden, since

40 considered in the differential diagnosis of relentless otorrhea and external auditory canal stenosis

41 steadily becoming glucose specialists by the relentless pressure of mutation accumulation, which has

42 e mutant, but not the wild-type, protein had relentless progression of motor neuron loss with concomi

43 ses of the illness by preparing them for the relentless progression of the disease and by supporting

44 -inflammatory therapies that may prevent the relentless progression of the disease.

45 th the aim of identifying the causes of such relentless progression through an insightful and critica

46 deprivation therapy experience relapse with relentless progression to lethal metastatic castration-r

47 ve diseases are characterized by late onset, relentless progression, and finally death.

48 rgo spontaneous regression while others show relentless progression.

49 type, ranging from spontaneous regression to relentless progression.

50 r genes usurp physiologic programs mandating relentless proliferation and growth.

51 Relentless proliferation associated with self-sufficienc

52 y through the division cycle, leading to the relentless proliferation characteristic of the neoplasti

53 Metastasis is the relentless pursuit of cancer to escape its primary site

54 treatment, and monitoring owe much to Tom's relentless pursuit of excellence in research and the tra

55 se research activity on metallic glasses and relentless pursuit of their structural description, the

56 In their relentless pursuit of thinness, individuals with anorexi

57 Two-thirds had an insidious onset and a relentless rather than stepwise progression of disabilit

58 ic neoplasm marked by local invasiveness and relentless recurrence.

59 viduals with anorexia nervosa (AN) engage in relentless restrictive eating and often become severely

60 D biosynthesis, it now may contribute to the relentless rise in skin cancer incidence in humans.

61 ent relapse and remission, and those who had relentless seizures.

62 Viruses are under relentless selective pressure from host immune defenses.

63 r inability to prevent the frequently, often relentless symptomatic recurrences of BV and to reduce s

64 he authors point out, they also counteract a relentless tendency for positive emotions to become bori

65 Confounding by indication is a relentless threat to validity in observational studies o