ライフサイエンスコーパス: relevance

1 rioritization of sensory input based on task relevance.

2 of expert opinion about their importance and relevance.

3 ak selection, casting doubt on their general relevance.

4 ological processes and are of great clinical relevance.

5 bsets of stimulation sites with motivational relevance.

6 ance this once promising therapy to clinical relevance.

7 inactivation, which might be of therapeutic relevance.

8 instruments validitity and general clinical relevance.

9 of Candida to species level has new clinical relevance.

10 g anti-ZIKV CD8(+) T cell responses of human relevance.

11 inery driving hepatic functions is of utmost relevance.

12 odel, which may have important translational relevance.

13 volutionarily conserved, implying biological relevance.

14 ynthetic activity of Poleta can have in vivo relevance.

15 diagnostic technique with auxiliary clinical relevance.

16 aging process may have significant clinical relevance.

17 memories in humans would be of high clinical relevance.

18 studies indicate that basophils might be of relevance.

19 ce of anthropogenic PM with worldwide health relevance.

20 pathogenesis with therapeutic and prognostic relevance.

21 ptoms showed a positive SPT without clinical relevance.

22 s longer follow-up to determine its clinical relevance.

23 notion that anti-BP180 IgE is of pathogenic relevance.

24 factants (NIS) are of both basic and applied relevance.

25 low as 2.2pM and within a range of clinical relevance.

26 duced CYP46A1 activation is of physiological relevance.

27 ular impairment carries important prognostic relevance.

28 etic variants more likely to have functional relevance.

29 integrate regulatory evidence and biological relevance.

30 vasion in vitro and confirmed their clinical relevance.

31 fic IgG and also IgE responses with clinical relevance.

32 labeling strategies to problems of clinical relevance.

33 rge class of metabolites with pharmaceutical relevance.

34 s and scientific insights with translational relevance.

35 Despite its relevance across a range of flows, helicity in real flui

36 rare genomic variants of potential clinical relevance and also disease modifiers related to coexisti

37 we highlight important research gaps and the relevance and applicability of ongoing natural range exp

38 We identified 10 PCPs of relevance and demonstrated that their use within 6 h of

39 mporal gene expression data based on maximum relevance and minimum redundancy criteria.

40 basis of motor rhythms and their behavioral relevance and offer the possibility of developing tACS a

41 ng of CEA in order to establish its clinical relevance and provide tools for real-time monitoring of

42 s, from 2005 to March 2011 were reviewed for relevance and reference lists were crosschecked for addi

43 these constructs and emphasize the clinical relevance and translation of these tasks in psychiatric

44 f experimental design rather than real-world relevance, and (2) any argument dependent on effect size

45 a public health issue of high socioeconomic relevance, and development of evidence-based action plan

46 prompted skepticism regarding their in vivo relevance, and most studies have been confined to cell c

47 hesis are well founded with clear biological relevance, and therefore, the premise warrants further i

48 ted MT1-MMP activation and its physiological relevance are not known.

49 in different assemblies and their functional relevance are subjects of intense debate.

50 on, only a few models, lacking physiological relevance, are available.

51 oss of chromosome Y (mLOY), and its clinical relevance, are unknown.

52 e supported on titanium dioxide, which is of relevance as a catalyst in, e.g., nitrogen oxide emissio

53 and protein level, and demonstrate that Her2 relevance as a tumor driver likely may vary even within

54 e properties are of particular physiological relevance, because these proteins remain unfolded for ex

55 ntral regions, with object category and task relevance both contributing significantly to the represe

56 pparatus is thus an important challenge with relevance both to the basic biology of animal communicat

57 We illustrate the physiological relevance by demonstrating that UPF1-augmented TumiD pro

58 ness to regular exercise is a topic of great relevance due to its potential role in personalized exer

59 with demonstrated synthetic and therapeutic relevance, five new phenylalanine ammonia lyase (PAL) en

60 erapeutic target for IBD, and has particular relevance for anti-TNF-resistant patients.

61 racteristics of dessert apple varieties with relevance for cider production will allow for informed d

62 transcription factor binding with particular relevance for cis-regulation.

63 The current disease severity index may have relevance for clinical practice, as well as for selectin

64 nction may also cause disease, with possible relevance for human disorders and in particular the brea

65 suggest that mistimed feeding has functional relevance for immune function and provide further eviden

66 asic HCV T cell immunology and have clinical relevance for immune protection of HCV-associated diseas

67 trafficking at the brain-CSF interface with relevance for immune surveillance in the healthy brain a

68 the photocycle of ReaChR and describe their relevance for its function.

69 as been well documented in monocultures, its relevance for mixed stands of varying species richness r

70 widely used animal model with translational relevance for neurodevelopmental psychiatric disorders s

71 are common in brain and likely of particular relevance for neuroscience and psychiatric disorders.

72 athologic, and clinical features, with clear relevance for patient management.

73 y process to induce analgesia with potential relevance for patient stratification.

74 stress perfusion and CFR, and (5) potential relevance for patients with risk factors or coronary art

75 wledge of the evolutionary history of MM has relevance for predicting patient outcomes and personaliz

76 eproducibility of target plasma, which is of relevance for R-LIBS applications.

77 asic HCV T cell immunology and have clinical relevance for redirecting T cells to target virally infe

78 s under force, a mechanism which could be of relevance for several physiological processes.Proteins f

79 s been widely researched recently due to its relevance for subsurface engineering applications includ

80 ailable since the 2008 version with clinical relevance for the diagnosis, prognosis, and therapy of p

81 psis genomes provided a potential functional relevance for these genes.

82 n reveal population and network phenomena of relevance for understanding mechanisms of consciousness.

83 These findings have clinical relevance for understanding the neurobiological basis of

84 esistant profiles, is certainly of paramount relevance, given its obvious effect on the chances of ap

85 igh-throughput screening (HTS) data to human relevance have been limited.

86 ow oscillations (SOs), appears of particular relevance here.

87 um chemical dynamics, given their functional relevance in all modern cells.

88 However, the precise assessment of in vivo relevance in different disease settings has been hampere

89 fic RNA cleavage, and as a result, they have relevance in gene regulation.

90 mice, a finding which may have translational relevance in HCC pathogenesis.

91 o address regulatory mechanisms and clinical relevance in normal human bronchial epithelial cells (NH

92 cinal chemistry programs for its therapeutic relevance in several (patho)physiologic processes.

93 topoiesis; (2) its alteration and functional relevance in the context of chronic and acute myeloid ma

94 wever, the evidence regarding their clinical relevance is inconsistent.

95 Of clinical relevance is that our data reveal that expression of IRS

96 Despite their relevance little information about physicochemical chara

97 Despite its environmental relevance, little attention has been given to cost-effec

98 Despite this evident physiological relevance, mechanistic understanding of NET formation is

99 Task relevance modulated the influence of predictions on beha

100 Crucially, task relevance modulated these spectral correlates, suggestin

101 This biology may have relevance not only to the pathophysiology of Alzheimer's

102 ved in neurons, supporting the physiological relevance of 5-HT2 receptor heterodimerization in vivo A

103 In the proposed approach we compute relevance of a gene by averaging F-statistic values calc

104 rall, these findings underscore the clinical relevance of AKT-independent pathways in tumors driven b

105 These findings reflect the important relevance of an intact intestinal barrier.

106 100% of BP serum samples, and the pathogenic relevance of anti-BP180 IgE has been suggested in variou

107 active IgE in BP, to evaluate the diagnostic relevance of anti-BP180 IgE in BP, and to correlate anti

108 discussions and investigations regarding the relevance of anti-glycan IgE for allergic diseases.

109 s, raising the question about the biological relevance of bistable lac induction in the natural setti

110 ate biological functions and the therapeutic relevance of Brr2.

111 f sustained BAT activation and highlight the relevance of cholesterol metabolism by the host for diet

112 The quantitative relevance of circulating lactate or other metabolic inte

113 ain elusive, prompting us to investigate the relevance of CXCR4 in vascular cell types for atheroprot

114 This highlights the relevance of degradation processes.

115 ntaminated leaves, our results emphasize the relevance of dietary exposure (e.g., via leaves) for sys

116 by text mining to evaluate functional marker relevance of discovered genes.

117 Systematic debate on the relevance of distinct imaging modalities held in 2 conse

118 Our data support the relevance of enhancing mitochondrial proteostasis to del

119 on in amphibians and highlight the potential relevance of fluorescence in visual perception in terres

120 Our data uncover the physiopathological relevance of fork reversal and illuminate a complex inte

121 osis (MS); however, the potential biological relevance of GALC variants to MS remains elusive.

122 To validate the in vivo relevance of genetic dependencies observed in human cell

123 Virtually nothing is known about the relevance of glycolysis in patients with allergic asthma

124 e use transgenic lines to define the in vivo relevance of HDAC1 and identify calcineurin-dependent se

125 d in other recent reviews; these include the relevance of herpes simplex encephalitis and of epilepsy

126 Given the emerging relevance of immunotherapies that boost pre-existing T c

127 ity in acute HF, thus, supporting functional relevance of impaired CgA processing in cardiovascular d

128 Our model jointly estimates the relevance of individual factors, refines gene set annota

129 However, the relevance of individual residential changes and their im

130 526 526 References 526 The relevance of infochemicals in the relationships between

131 Given the translational relevance of LAG3 and the heightened interest in the imp

132 owever, both the mechanism and physiological relevance of LGR5 internalization are unclear.

133 We then tested the physiological relevance of LGR5 internalization blockade in vivo A LGR

134 Given the relevance of lungfishes in evolutionary terms, the prese

135 s animal model and highlighting the clinical relevance of lymphangiogenesis in corneal fluid homeosta

136 he importance of transient dynamics, and the relevance of manipulating a cascade of destabilizatons f

137 on approaches for investigating the role and relevance of MCs in various diseases.

138 However, the relevance of menaquinones produced by gut bacteria to vi

139 strategies for determining the true clinical relevance of metabolites observed in association with ca

140 the mechanistic implementation and clinical relevance of microbiome alterations on disease susceptib

141 This perspective highlights the relevance of micropipette-aspirated single-particle trac

142 irmed model-based predictions on the limited relevance of microplastic for bioaccumulation under envi

143 In addition, we discuss the relevance of mitochondrial targeted treatments to mental

144 These findings highlight the relevance of MLL2 as a drug target in MLL-rearranged leu

145 We also investigate the clinical relevance of MOG-IgG through a longitudinal analysis of

146 To understand the functional relevance of mTOR enzymatic activity in beta-cell develo

147 These data demonstrate the relevance of Nbeal2 in mast cells above and beyond granu

148 To test the physiological relevance of noncanonical TR signaling, we generated kno

149 tic and expression data revealed the disease relevance of NPAS-regulated genes and pathways.

150 We discuss the possible relevance of our findings to the mechanism of trehalose

151 Cell-based assay supports the physiological relevance of our findings.

152 re highly expressed, supporting the clinical relevance of our observations in mice.

153 The potential relevance of our observations is supported by the down-r

154 To study the relevance of pericardial clusters during inflammatory re

155 ing field of photopharmacology indicates the relevance of photocontrol in future medicine.

156 ideas stressing the multifaceted biological relevance of phytoplankton chytridiomycosis, resulting f

157 The relevance of polar effects is supported by theoretical c

158 tions hamper the interpretation and clinical relevance of previous studies.

159 ue of LumC13 (Lumikine) and aid its clinical relevance of promoting the healing of corneal epithelium

160 This highlights the clinical relevance of reducing ICH by using apixaban rather than

161 However, the prognostic relevance of remnant liver ischemia (RLI) after resectio

162 The aim of the study was to assess the relevance of resection margin status for survival after

163 To assess the relevance of resection margin status for survival outcom

164 These data provide new insights into the relevance of RNA pseudouridylation in mitochondrial gene

165 displays strong conservation, the functional relevance of SD-aSD interactions in plastid translation

166 al predictability of visual targets, and the relevance of spatial/temporal information provided by au

167 ues among clinicians as to both the clinical relevance of subclinical BPV thrombosis and the value of

168 tunities, but the prevalence and therapeutic relevance of such effects (gain of function and dominant

169 als (CD) is not well understood, despite the relevance of such effects to long-term outcomes.

170 wever, the underlying mechanisms and disease relevance of such lysosome accumulations are not well un

171 e molecules and investigating the diagnostic relevance of such molecules in childhood.

172 easonable and necessary that we question the relevance of such small effects, we present examples in

173 olone, was used as a criterion to assess the relevance of SUCNR1/GPR91 expression mediating allergic

174 These findings emphasize the relevance of sufficient intrauterine oxygenation for nor

175 Overall, the present work highlights the relevance of T2 as a key bioactive hormone, and reveals

176 he case study, we show the higher biological relevance of the biomarkers selected by our approach.

177 y to AD, the action of IFN, and the possible relevance of the different types of DNA damage to AD-in

178 The functional relevance of the gut mycobiome was confirmed in fecal tr

179 ltiradiene is the relevant precursor and the relevance of the identified diterpene synthases, enablin

180 e the time required to assess the biological relevance of the IgG microheterogeneities thus providing

181 function has been reported, but the in vivo relevance of the in vitro observations is still unclear.

182 The functional relevance of the innate immune system has not yet been d

183 The relevance of the innate immune system, and monocytes in

184 n this study, we investigated the biological relevance of the interaction between ICP34.5 and TANK-bi

185 The functional relevance of the inverted repeat structure (IR/DR) in a

186 To confirm the physiologic relevance of the MAP17-SGLT2 interaction, we studied a c

187 The relevance of the multi-parameter electrochemical data fo

188 We also examine the biological relevance of the network profiles.

189 The clinical relevance of the newly characterized AKT1 VNTR merits in

190 tractant serine, pointing to a physiological relevance of the observed thermotactic behavior.

191 active in the basal state and the functional relevance of the observed tonic signaling heterogeneity

192 an oscillator and explored the physiological relevance of the oscillator structure for accurately tim

193 sults indicate an increasing epidemiological relevance of the pathogen and the need for in-depth inve

194 The biological relevance of the present method has been demonstrated by

195 excitatory synaptic function, we address the relevance of the proteolytic processing of presynaptic n

196 of thiols with low pKa values emphasizes the relevance of the protonation step in the ring-opening re

197 regulator of ESR1 and revealed the clinical relevance of the RNA-binding protein MSI2 in breast canc

198 results, together with the known functional relevance of the three genes to LMI, suggested that the

199 onic substrate, and confirmed the functional relevance of these amino acids using a targeted mutagene

200 Furthermore, we confirm the clinical relevance of these cells by demonstrating a direct corre

201 de axonal damage in culture, but the in vivo relevance of these findings and the potential posttransl

202 The relevance of these findings and their possible physiolog

203 The translational relevance of these findings is highlighted by the higher

204 The relevance of these findings relative to visual acuity, h

205 The relevance of these issues was already recognized in the

206 However, the physiological relevance of these observations to adult ovarian functio

207 communication in microalgae, because of the relevance of these organisms for global primary producti

208 s, topographical organization and perceptual relevance of these representations.

209 ssion analysis has allowed us to confirm the relevance of these targets for EOC and further provided

210 To assess the clinical relevance of this ADAM17-mediated ACE2 shedding in hyper

211 HA-specific inhibitors, indicating the high relevance of this cavity for drug design.

212 However, the physiological relevance of this discovery remained unclear, as we were

213 The relevance of this diversity to maintain self-tolerance r

214 We discuss the potential relevance of this dual chemoreceptor feedback to cardior

215 To test the physiological relevance of this hypothesis, we first showed that macro

216 resistance arteries supported the biological relevance of this mechanism.

217 Furthermore, we confirm the in vivo relevance of this pathway in our IL-15 transgenic mouse

218 sphotyrosine phosphatase 1B (PTP1B), and the relevance of this pathway to VEGF-induced angiogenesis,

219 Collectively, our data support the clinical relevance of this protease in human influenza pathogenes

220 However, the functional relevance of this strong collecting duct epithelial barr

221 s, healthy volunteers, and patients, yet the relevance of this to pharmacotherapeutic actions remains

222 This work establishes the relevance of thymic function, measured by sj/beta-TREC r

223 The relevance of UMOD for CKD is clear, because the encoded

224 rge clones, underscoring the feasibility and relevance of understanding drivers of the differences.

225 Here we address the relevance of using a specific Anopheles salivary biomark

226 ATPase and to fully evaluate the therapeutic relevance of V-ATPase in human diseases.

227 ecting ECM accumulation are limited in their relevance or throughput.

228 Of great relevance, our preliminary toxicological analysis indica

229 Since the environmental relevance, particularly bioavailability, rises with decr

230 CLINICAL RELEVANCE: Relative safety of ranibizumab and bevacizuma

231 observed in the cortex, but their functional relevance remains unknown.

232 As a step toward biological relevance, results are presented for the unprotected ami

233 Conclusion and Relevance: Statin use increased substantially in the las

234 Conclusion and Relevance: Surgical treatment delays were common but wer

235 (>500,000) and better functional biological relevance than comparable resources.

236 Of relevance, the disulfide bond formation was much slower

237 Of further relevance, the DNA arrays are of tunable dimensions, and

238 Despite its high clinical relevance, the evolutionary origin of USA300 remained un

239 Despite its clear clinical relevance, the neural circuitry governing the maladaptiv

240 er a widely studied bias with special policy relevance: the default effect, which is the tendency to

241 Despite their medical relevance, there is a gap in our understanding of the ph

242 es and clades tend to be of limited clinical relevance, they could potentially serve as reservoirs of

243 pose a temporal minimum redundancy - maximum relevance (TMRMR) feature selection approach, which is a

244 human AD patients, indicating its potential relevance to AD.

245 include water, alcohols, and solutions with relevance to biology and energy technology.

246 es for plant lignocellulose degradation with relevance to biotechnological applications as biofuel pr

247 a fundamental cell-biological question with relevance to cancers, which often exhibit enlarged nucle

248 en based on strength of association with and relevance to cardiogenic shock.

249 benzylic borylation reactions, which are of relevance to catalytic methylarene (di)borylation, are r

250 The study has particular relevance to cultural heritage, where heterogeneous laye

251 with age, it is of fundamental and clinical relevance to decipher new determinants that control TEC

252 directly on the podocyte, with translational relevance to designing new selective synthetic Gc molecu

253 ere, we discuss the molecular mechanisms and relevance to disease of necroptosis.

254 This topic is of practical relevance to diverse fields, ranging from neuroscience t

255 teria and biomarker, which would be of great relevance to either outcome evaluation or study design.

256 This material system has relevance to emerging classes of biologically and enviro

257 ), and citizen science, and to explore TEK's relevance to environmental health research.

258 blic datasets suggest that our data may have relevance to human cancers.

259 d embryonic survival, with important broader relevance to human female infertility and mitochondrial

260 ion in the taiep rat model and determine its relevance to human white matter disease.

261 2 kinases has not been examined despite its relevance to immune-based therapies.

262 dy this parasite and that have physiological relevance to in vivo infection remain suboptimal.

263 ficial receptors is important because of its relevance to many biological and environmental applicati

264 Our findings have primary relevance to obese individuals who are at an increased r

265 of this class of peptides and discusses the relevance to organismal metabolism.

266 he effect of E3 ligase binding affinity with relevance to other drug discovery efforts in targeted pr

267 infection, but the underlying mechanism and relevance to other viruses or in vivo infections remaine

268 uced greater changes in gene expression with relevance to oxidative stress, apoptosis, and ion transp

269 for NRG2 in the modulation of behaviors with relevance to psychiatric disorders.

270 ecies coordinated to a metal ion of possible relevance to reductive elimination/oxidation addition re

271 pathway) medium spiny neurons (MSNs) and its relevance to repetitive grooming behavior in Shank3B mut

272 ets demonstrated UClncR's accuracy and their relevance to sample clinical phenotypes.

273 ts this energy wasting reaction is of direct relevance to solar energy conversion.

274 embling key aspects of ALS, highlighting its relevance to study disease pathogenesis.

275 ntify the patterns of SERT pathology and the relevance to symptoms.

276 alance is controlled in neurons and may bear relevance to synaptic dysfunction in autism.

277 These interrelationships may have relevance to the biological actions of retinol, includin

278 indings provide key clinical and preclinical relevance to the conformational immunoassay, and provide

279 y deleterious genetic variations in genes of relevance to the cornification process.

280 tures is currently of great interest due its relevance to the design of novel mechanical metamaterial

281 These observations are of likely relevance to the influence of ketamine upon mood and its

282 r and involved in lipid homeostasis, but its relevance to the long-term risk of developing metabolic

283 hormone, sclerostin, or vitamin D and their relevance to the management of different pathologies in

284 patients, summarize previous publications of relevance to this field, and discuss future directions.

285 Of particular relevance to this study, is the antibiotic abuse in pig

286 y large-effect regulatory variants and their relevance to traits.

287 or nociceptive processing in SSDHN with high relevance to transcriptional changes and the development

288 the genetics of neurocognitive function with relevance to understanding the pathophysiology of neurop

289 CLINICAL RELEVANCE: To analyze vitreoretinal procedural trends, w

290 nal rationale behind the 14-day rule and its relevance today in light of advances in human embryo cul

291 cation provides estimates of direct clinical relevance useful to assist clinical ascertainment, genet

292 rogramming-support vector machine (SDP-SVM), relevance vector machine (RVM) and Ada-boost relevance v

293 relevance vector machine (RVM) and Ada-boost relevance vector machine are compared and evaluated with

294 Pathophysiological relevance was demonstrated when the codelivery of L. reu

295 ations, and 49 articles of possible clinical relevance were reviewed in full text.

296 stopathologic findings may retain prognostic relevance when a genetic diagnosis is established.

297 Moreover, FOXP1-SHQ1 deletion has prognostic relevance, with cancer recurrence associated with combin

298 ve structural changes are of direct clinical relevance, with progressive changes on OCT often precedi

299 opportunistic human pathogens of increasing relevance worldwide.

300 insult in human organs is of major clinical relevance, yet remains incompletely understood.