ライフサイエンスコーパス: relevance for

1 Clinical relevance for a future sting has not yet been investigat

2 Our findings are of high relevance for a general understanding of the assembly of

3 solutions is a physical property of central relevance for a large number of applications in material

4 coding schemes depend upon their ecological relevance for a particular species, particularly when de

5 l solutions, and show the findings practical relevance for a simple model scenario.

6 opological insulators, and demonstrate their relevance for a wide range of acoustic applications, inc

7 In addition, they are of considerable relevance for accounts of sleep-dependent memory reproce

8 wastewater treatment systems, including its relevance for accumulation of ammonium.

9 henotype are controversial and their in vivo relevance for AD pathogenesis is unknown.

10 sitions at near ambient temperature has wide relevance for adsorption-based water purification.

11 nces in emotional responding, with potential relevance for affective disorders.

12 eral of our DMRs are at genes with potential relevance for age-related disease.

13 , which suggests that it has little clinical relevance for an individual's glycemic status.

14 component animal viruses and their potential relevance for animal and human health.

15 erapeutic target for IBD, and has particular relevance for anti-TNF-resistant patients.

16 ns important neutralizing B-cell epitopes of relevance for antibody-mediated protection against genit

17 The optical Stark effect has practical relevance for applications, including quantum informatio

18 mmunoprotective effects may have therapeutic relevance for asthma.

19 med curation projects in areas of particular relevance for biomedical sciences, such as the ubiquitin

20 These findings have clinical relevance for both diagnosis and selection of patients f

21 rm CD8(+) T cell populations, a finding with relevance for both vaccine design and prevention of infl

22 These results are of relevance for both vaccine design and the identification

23 the human brain across multiple levels, with relevance for brain function and disease.

24 With potential relevance for brain-mapping work, hydrogel-based structu

25 The physiological relevance for breast cancer cells is that as PA can acti

26 ate that temperatures during freezing are of relevance for bubble formation and air seeding.

27 signalling in addition to adhesion may have relevance for cancer therapy.

28 of force generation by myosins have general relevance for cardiac and non-muscle myosins as well as

29 n SNX27-retromer assembly and its functional relevance for cargo sorting.

30 Au nanoclusters are of technological relevance for catalysis, photonics, sensors, and of fund

31 ys for signal transduction is evident, their relevance for cellular differentiation and morphogenesis

32 However, their relevance for cellular transcription has not been proved

33 release from neutrophils is of high clinical relevance for CF.

34 s of these natural products is of particular relevance for chemical biology and medicinal chemistry.

35 ges and further research on their functional relevance for children's health.

36 the 13-cis photocycle is of minor functional relevance for ChR2.

37 ide release in acute hypoxia, as well as its relevance for chronic pulmonary oxygen sensing, remain u

38 racteristics of dessert apple varieties with relevance for cider production will allow for informed d

39 transcription factor binding with particular relevance for cis-regulation.

40 Ox emission sources is therefore of immanent relevance for climate and air chemistry models as well a

41 esis, organ formation, and homeostasis, with relevance for clinical conditions.

42 These findings may have relevance for clinical haematopoietic stem cell transpla

43 These findings are of relevance for clinical practice and research and call in

44 Our findings may have relevance for clinical practice because they give no sup

45 The current disease severity index may have relevance for clinical practice, as well as for selectin

46 n sickness associated with inflammation with relevance for clinical study of pulmonary edema.

47 The compound-specific differences have relevance for clinical trials targeting GPVI-collagen in

48 thway responsible for modifying CLV3 and its relevance for CLV signaling are unknown.

49 ew glycoproteins with a potential functional relevance for CNS development.

50 ions have been poorly studied, despite their relevance for conservation of this endangered species.

51 on, progression, and modifying factors, with relevance for counseling of HSP families and planning of

52 model of care for a high-risk population has relevance for decision making about health policy.

53 Besides its relevance for declarative memory functions, hippocampal

54 ssociated with extraoral infections, but its relevance for dental caries has only been theorized to d

55 Results have relevance for designing interventions for children from

56 This has relevance for designing new photo-responsive smart or ad

57 lity of TERS is demonstrated, indicating its relevance for detecting molecular variations.

58 This need is of particular relevance for developing countries, since they host the

59 nderpinnings of this variability is of great relevance for developing individualized prevention strat

60 in the amplification of Wnt signaling, with relevance for development, homeostasis and cancer.

61 entify here a novel pathway with prospective relevance for diagnosis and customization of breast canc

62 and pathological functions and thus of great relevance for diagnostic and therapeutic approaches in c

63 , and CD34(-)/CD14(-) PBMC subsets and their relevance for different proangiogenic properties.

64 ication of p97 domains and its activity with relevance for disease pathogenesis.

65 esponse to glucocorticoids, and define their relevance for disease severity.

66 T1P expression therefore is of direct relevance for disease.

67 ycles is present in molecules of therapeutic relevance for diverse applications ranging from infectio

68 This may have relevance for diverse disease conditions, like Alzheimer

69 r mechanism of HIPK2 activation and show its relevance for DNA damage-induced apoptosis in cellulo an

70 for DNA breathing fluctuations of potential relevance for DNA-protein interactions.

71 rge density wave formation may be of general relevance for driving phase transitions into other broke

72 d with type 2 diabetes (T2D); however, their relevance for drug development is not yet clear.

73 a or -tolerance within Symbiodinium spp. has relevance for early stages of host-Symbiodinium interact

74 e report here on an effort to evaluate their relevance for efforts to harness science in support of s

75 contribute to protection, an issue of great relevance for enhanced subunit vaccination.

76 ity of virion-associated Env, which may have relevance for Env based vaccine strategies for HIV-1.

77 oxidative stress as a pathway of therapeutic relevance for ERMS.

78 Our results might be of relevance for establishing higher awareness in the healt

79 Our findings have relevance for etiology, diagnosis and treatment of disea

80 Cs), thus demonstrating biocompatibility and relevance for evaluating drug metabolism and toxicity.

81 uce two new concepts of significant clinical relevance for evaluating the mutational profile.

82 rganic molecules of questionable biochemical relevance (for example, those used in Belousov-Zhabotins

83 d to 700 genes), several are of pathological relevance for fetal growth restriction.

84 maternal-fetal interface, and discuss their relevance for fetal tolerance.

85 stric activity, which may have physiological relevance for food intake and gastric function.

86 nd selected 27 articles of possible clinical relevance for full-text review.

87 ity of the motif and its surprisingly strong relevance for function should render the introduced appr

88 Despite its relevance for fundamental ecological processes, however,

89 he Rab7-like Ypt7 protein to determine their relevance for fusion.

90 .0 mA anodal tDCS, which may be of practical relevance for future optimizations.

91 Chromatin is of major relevance for gene expression, cell division, and differ

92 dence of these networks and their functional relevance for genome organization, loss of the Polycomb

93 eased release probability, demonstrating its relevance for glutamatergic transmission.

94 ther study, these results may have immediate relevance for guideline committees, laboratory leadershi

95 s, this study may have important therapeutic relevance for HD.

96 tion, is increasingly recognized as being of relevance for health and disease, and therefore, this to

97 RI patterns can embed diverse information of relevance for health and disease, many of them have not

98 remains unknown, and only a few targets with relevance for heart physiology have been analyzed for th

99 ed by partial HPV genotyping tests also have relevance for HIV-positive women.

100 esponse; however, its role in DNA repair and relevance for human cancer remain unclear.

101 onferred by ARID1A mutation would have major relevance for human cancer.

102 ical auditory nervous system is of paramount relevance for human communication, and it has been shown

103 the peripheral nervous system with potential relevance for human diseases.

104 nction may also cause disease, with possible relevance for human disorders and in particular the brea

105 e required to validate the results and their relevance for human health risk assessment of PAH-contam

106 ding of basic mechanisms that might not have relevance for human health.

107 differentiation of hepatocytes that may have relevance for human liver disease and metabolic dysregul

108 ble strategy for nerve repair with potential relevance for human patients.

109 The physiological relevance for humoral (auto-)immunity was corroborated b

110 networks include genes and pathways of known relevance for IBD; in particular, the solutions found hi

111 the chance to detect biomarker signatures of relevance for identification of disease subphenotypes.

112 se in basic understanding, our findings have relevance for identifying unique neurodevelopmental toxi

113 suggest that mistimed feeding has functional relevance for immune function and provide further eviden

114 asic HCV T cell immunology and have clinical relevance for immune protection of HCV-associated diseas

115 ane trafficking routes and its physiological relevance for immune responses is still largely unclear.

116 trafficking at the brain-CSF interface with relevance for immune surveillance in the healthy brain a

117 These data have relevance for immunity and vaccination during persisting

118 many bacteria, plants, and mammals, but its relevance for important model organisms, including Caeno

119 and this knowledge can then be mined for its relevance for improved therapeutics and its impact on ps

120 Of relevance for in vitro models of (dys)functional cortica

121 nces, annotation information, and functional relevance for inducing correlated gene expression.

122 Our results are of clinical relevance for infants, healthcare systems, and policy ma

123 on with C. parapsilosis, which has potential relevance for infections with other fungal pathogens.

124 al for extending this framework to traits of relevance for infectious disease dynamics.

125 ficant interest in medicine, with particular relevance for infectious diseases and cancer.

126 dea that subunit exchange in CaMKII may have relevance for information storage resulting from brief c

127 Priapulid decay also have unexpected relevance for interpretation of myomeres in fossil chord

128 the photocycle of ReaChR and describe their relevance for its function.

129 ncient TPC complex in trafficking that holds relevance for lysosomal proliferative scenarios observed

130 ere we use an invertebrate animal model with relevance for mammalian pain.

131 MAT gene function are likely to be of broad relevance for manipulation of other asexual fungi of eco

132 in controlling the decoding process may hold relevance for many other ribosomal mutations known to in

133 t to elements of cellular differentiation of relevance for mature leaf photosynthetic performance.

134 The activity cliff concept is of high relevance for medicinal chemistry.

135 n assay to identify compounds of therapeutic relevance for melanoma.

136 neuronal oscillations and are of functional relevance for memory performance.

137 en the immune system and the gut with strong relevance for metabolic regulation in context of inflamm

138 ll molecules and metabolites with functional relevance for microbe-host interactions.

139 rganelles in metazoans and the physiological relevance for migration is unclear.

140 Conclusions and Relevance: For mild symptoms of nausea and emesis of pre

141 as been well documented in monocultures, its relevance for mixed stands of varying species richness r

142 he resulting character data, with particular relevance for morphological phylogenetic analyses which

143 c cells, a process that may be of particular relevance for myocardial repair and regeneration.

144 dability of DNA plays an important role with relevance for myriad of essential cellular mechanisms.

145 Unfortunately, their relevance for nanoparticles at low concentration (below

146 operties of these cells and their functional relevance for network computations remain unknown.

147 widely used animal model with translational relevance for neurodevelopmental psychiatric disorders s

148 are common in brain and likely of particular relevance for neuroscience and psychiatric disorders.

149 l systems with great basic and translational relevance for neuroscience.

150 al role in arterial thrombosis and its minor relevance for normal hemostasis.

151 y of cell cycle progression, underlining its relevance for normal tissue maintenance.

152 g scientific justification and translational relevance for novel therapeutic combinations for childho

153 school-age assessment of IQ, a measure whose relevance for occupational success in adulthood is well

154 nal onchocerciasis research, with particular relevance for ongoing control programmes, and boost effo

155 erentiation locally within the lung maybe of relevance for optimal control of airway eosinophilia and

156 regioselective aromatic hydroxylation is of relevance for optimization of flavin-dependent biocataly

157 ecules have been widely studied due to their relevance for organic and dye-sensitised solar cells.

158 erstanding of titanium(III)-catalysis and of relevance for other metal-catalyzed radical reactions.

159 ment sizes (<60 hectares), which has limited relevance for our analyses conducted using 250,000-hecta

160 We included articles based on their relevance for our review topic.

161 l targets regulated by this gene, with broad relevance for our understanding of ID and related syndro

162 These findings have immediate relevance for our understanding of sphingosine-1-phospha

163 These findings have relevance for our understanding of the processing of nat

164 a tumorigenic phenotype that ultimately has relevance for outcome of HCC and other cancer patients.

165 Of particular relevance for paleodietary reconstruction are metals pre

166 model system of calcification with specific relevance for pathological mineralization.

167 linical efficacy, and adverse events and the relevance for patient care.

168 athologic, and clinical features, with clear relevance for patient management.

169 y process to induce analgesia with potential relevance for patient stratification.

170 ternally validated, that has direct clinical relevance for patients and clinicians to weigh the benef

171 Our data have particular relevance for patients at higher risk of spontaneous ret

172 These findings suggest potential clinical relevance for patients with acquired or inherited gain-o

173 an rhythms in humans and may have particular relevance for patients with circadian rhythm disorders,

174 this review, we first define frailty and its relevance for patients with hematologic malignancy.

175 stress perfusion and CFR, and (5) potential relevance for patients with risk factors or coronary art

176 gents in view of the potential high clinical relevance for patients with TNBC irrespective of race or

177 ory gating of auditory sensory processes has relevance for patients' clinical symptoms or cognitive p

178 ral practical and ethical dilemmas of global relevance for patients, clinicians, and policy makers.

179 Conclusions and Relevance: For patients who are injured, young, and unin

180 in generating temporal predictions and their relevance for perception, attention, and awareness.SIGNI

181 ust properties of neural circuits, but their relevance for perceptual judgments, such as the behavior

182 nts of Gli1/DNA interaction highlights their relevance for pharmacologic interference of Gli signalin

183 The transmission-limiting benefit of AL has relevance for policymakers planning optimal utilization

184 wledge of the evolutionary history of MM has relevance for predicting patient outcomes and personaliz

185 the extent of polysulfide formation and its relevance for product formation pathways remains enigmat

186 cacy of VRC07-523 and its potential clinical relevance for protecting against HIV-1 infection in huma

187 munity and highlights some insights into its relevance for psychiatric diseases.

188 This finding has relevance for public health policies in many countries w

189 y important clinical implications as well as relevance for public health policy regarding the widespr

190 tiotemporal resolution and higher vertebrate relevance for quantitative neuropharmacological profilin

191 eproducibility of target plasma, which is of relevance for R-LIBS applications.

192 Because the GalNAc occupancy pattern is of relevance for receptor binding of gC-1, the data provide

193 In this study, its functional relevance for recruitment of polymorphonuclear neutrophi

194 asic HCV T cell immunology and have clinical relevance for redirecting T cells to target virally infe

195 c-kit(pos) cardiac stem cells (eCSCs), whose relevance for regeneration is controversial.

196 ghting recent findings that strengthen their relevance for schizophrenia and autism and are starting

197 ective and cognitive symptoms that have high relevance for schizophrenia and other psychiatric disord

198 g the most highly pursued drug targets, with relevance for several neurological diseases, and a numbe

199 s under force, a mechanism which could be of relevance for several physiological processes.Proteins f

200 ally dimorphic change over adolescence--with relevance for sex-biased mental disorders emerging in yo

201 t, with direct diagnostic and/or therapeutic relevance for SHH MB.

202 subject of considerable attention due to its relevance for spin-based quantum computation using semic

203 tantly, the findings from our study may have relevance for SRS and highlight a potentially underrepor

204 row EPCR(+) LT-HSCs, with potential clinical relevance for stem cell transplantation.

205 ating pathogen host tropism as well as their relevance for studying the tropism of several important

206 to postimplantation stages and therefore has relevance for subsequent development.

207 s been widely researched recently due to its relevance for subsurface engineering applications includ

208 ave historically been assumed to have little relevance for such neuroendocrine control, we investigat

209 In addition to its relevance for survival, this integration underlies patho

210 s activated BCR signaling networks and their relevance for targeted therapies in BL remain elusive.

211 These findings have clinical relevance for targeting c-MET in PNETs.

212 tion even in these simple sites and to their relevance for testing different models of recognition.

213 This might be of relevance for the action of GLP-1 mimetics now widely us

214 leon protein whose properties bear potential relevance for the aggregation properties of ataxin-1 and

215 re have the potential to be of physiological relevance for the biological process underlying the deve

216 ng ability were evaluated in regard to their relevance for the catalytic process.

217 ed inflammatory disorders, which could be of relevance for the clinical application of modern therape

218 Functional relevance for the CREB-binding site was demonstrated wit

219 of OFF-induced mineral deposition, which has relevance for the design of bone tissue engineering stra

220 Furthermore, our results have relevance for the design of novel immunotherapeutics tha

221 These data may be of relevance for the design of optimal immunization regimen

222 The reported approach holds relevance for the development of high-performance molecu

223 essant properties of (R,S)-ketamine and have relevance for the development of next-generation, rapid-

224 Saturated fatty acids are thought to be of relevance for the development of non-alcoholic fatty liv

225 t the behavioral and cellular level may have relevance for the development of novel therapeutics for

226 l, basic amino acids described here may have relevance for the development of other peptidic and pept

227 ation of risky decision-making, and may have relevance for the development of pharmacotherapies for d

228 e, this structural information has potential relevance for the development of therapeutics for neurod

229 ailable since the 2008 version with clinical relevance for the diagnosis, prognosis, and therapy of p

230 ALK2 signaling are likely to be of clinical relevance for the diverse ALK2 mutant proteins associate

231 um species, yet we know little regarding its relevance for the establishment of symbiosis under diffe

232 association between age and smoking may have relevance for the etiology of age-related macular degene

233 h IOP is especially interesting and may have relevance for the etiology of glaucoma, while the associ

234 apping or distinct, which has clear clinical relevance for the evaluation of their associated clinica

235 The findings have relevance for the evolution of autonomous systems that a

236 may uncover novel mechanisms of significant relevance for the future pharmacological targeting of th

237 sis and shows that this function is of major relevance for the growth and development of vascular pla

238 ion, translational experiments underline the relevance for the human system.

239 Our results have far-reaching relevance for the identification of conserved pathologic

240 ndividuals, but not for others, and may have relevance for the increased vulnerability for some psych

241 or ECS mutations to affect GPCR function has relevance for the increasing number of nonsynonymous sin

242 es remain to be shown, these findings are of relevance for the interpretation of parasite clearance t

243 Precision medicine is of broad relevance for the management of asthma, rhinitis, and at

244 However, its relevance for the modulation of allergic responses in th

245 y siderite, an Fe(II) carbonate mineral with relevance for the near-field of high-level radioactive w

246 Beyond its relevance for the neuronal basis of coherent BOLD signal

247 ssue development-related genes, with special relevance for the neuropeptide galanin that also reveale

248 cted ways [1-3], a feature with considerable relevance for the ongoing debate over the evolutionary o

249 oplasmas), the data presented here may be of relevance for the optimization of purine nucleoside-base

250 (JG) cells of the kidney, but may also have relevance for the physiologic integrity of the kidney.

251 e needed to determine its clinical value and relevance for the prediction of survival prognosis.

252 it and safety of these agents have immediate relevance for the prevention and treatment of cardiovasc

253 correlated with ecological and physiological relevance for the producer.

254 Our results not only have relevance for the progeria-like side effects of certain

255 ramework provided by the current model is of relevance for the rational design of allosteric activato

256 ting the water oxidation catalysis is of key relevance for the rationalization and the design of effi

257 nge suggests that this process is of general relevance for the relaxation dynamics in laser produced

258 The findings have broad relevance for the study of astrocyte-neuron interactions

259 CD spectroscopy has special relevance for the study of membrane proteins, which are

260 ition of retinoic acid biosynthesis may have relevance for the treatment of obesity and in the develo

261 This might be of clinical relevance for the understanding of critical periods disr

262 aturally occurring genetic variability is of relevance for the understanding of disease mechanisms in

263 ible to analytical calculations but of great relevance for the understanding of several natural and t

264 Conclusions and Relevance: For the past 15 years, morbidity, mortality,

265 light-induced charge separation, with direct relevance for their implementation in photocatalysis.

266 multisensory signals in PPS is of particular relevance for theoretical models and simulations of BSC

267 ut may also indicate potential translational relevance for therapeutic strategies targeting APP proce

268 nct roles in LuADC development with possible relevance for therapeutic target development.

269 n at the molecular level could be of pivotal relevance for therapy.

270 psis genomes provided a potential functional relevance for these genes.

271 re indicate, for the first time, a potential relevance for these metabolites in PCB-induced thyroid d

272 d receptors, our findings may have a general relevance for these receptors and may guide the design o

273 In support of a physiological relevance for these results, intraperitoneal administrat

274 olor and asymmetric reflectivity behavior of relevance for thin-film applications.

275 In studies to assess possible clinical relevance for this discovery, we found that antimyosin a

276 xtracted based on author consensus regarding relevance for this review.

277 osynthesis in vivo, demonstrating functional relevance for this unique feature.

278 results are discussed with respect to their relevance for transcription in organello and to the evol

279 ng treatments for SJS/TEN, which is of great relevance for treating physicians.

280 rapy for complex CNS infections and may have relevance for treatment duration and assessment of persi

281 These results may have relevance for trials of maraviroc for HIV preexposure pr

282 cycle associated 3 (CDCA3) were of confirmed relevance for tumor biology.

283 TR under identical conditions reinforces its relevance for understanding CFTR function.

284 d high-resolution molecular maps of putative relevance for understanding disease initiation and progr

285 ntal windows in psychiatric disorders, their relevance for understanding disease progression and thei

286 These findings have relevance for understanding evolutionary roots of mammal

287 tic loci to specific tumor subtypes may have relevance for understanding glioma biology, and for deve

288 n reveal population and network phenomena of relevance for understanding mechanisms of consciousness.

289 These results are of relevance for understanding modulation of ROS signaling

290 Moreover, this study might be of relevance for understanding the basic aspects of HIV-1 i

291 activity of TrxR1 is therefore of potential relevance for understanding the mechanisms of redox regu

292 These findings have clinical relevance for understanding the neurobiological basis of

293 d acyl chain length composition, which is of relevance for understanding the regulation of drug-induc

294 teraction with its mammalian hosts and their relevance for understanding the selective pressures acti

295 eterminants for viral control with potential relevance for vaccine development.

296 serum and plasma MPO levels, which may have relevance for various acute and chronic inflammatory dis

297 on IFN-alpha-based therapies and functional relevance for viral evasion and IFN resistance.

298 into the pathogenesis of PCA that also bears relevance for vision in typical AD.

299 earning account that seem to have particular relevance for visual recognition of social information i

300 y of amphibians to environmental change, and relevance for whether adaptation can keep pace with clim