1 ved in neurons, supporting the physiological
relevance of 5-HT2 receptor heterodimerization in vivo A
2 In the proposed approach we compute
relevance of a gene by averaging F-statistic values calc
3 sis model system to investigate the clinical
relevance of a novel virus-vectored (VV) tuberculosis va
4 In this study we aimed to define the
relevance of adipose tissue ERalpha during high-fat diet
5 rall, these findings underscore the clinical
relevance of AKT-independent pathways in tumors driven b
6 nto the physics of glasses and reinforce the
relevance of an entropy crisis for understanding their f
7 These findings reflect the important
relevance of an intact intestinal barrier.
8 100% of BP serum samples, and the pathogenic
relevance of anti-BP180 IgE has been suggested in variou
9 active IgE in BP, to evaluate the diagnostic
relevance of anti-BP180 IgE in BP, and to correlate anti
10 discussions and investigations regarding the
relevance of anti-glycan IgE for allergic diseases.
11 The behavioral
relevance of any stimulus needs to be learned, though, a
12 The
relevance of aPC-mediated Nlrp3 inflammasome suppression
13 l provides a much-needed tool to explore the
relevance of asymptomatic and symptomatic visceral leish
14 The attributed functional
relevance of axon regrowth, however, will depend on seve
15 s, raising the question about the biological
relevance of bistable lac induction in the natural setti
16 ate biological functions and the therapeutic
relevance of Brr2.
17 complete tumor rejection, demonstrating the
relevance of CD25 as a therapeutic target and promising
18 to investigate the phenotype and functional
relevance of CD49d(+) PMNs.
19 infection models, although the physiological
relevance of cell lines, particularly for host-pathogen
20 ploration into the functional and prognostic
relevance of ceRNA interaction in GBM.
21 To assess the
relevance of changes in glycolytic activity, we determin
22 f sustained BAT activation and highlight the
relevance of cholesterol metabolism by the host for diet
23 The quantitative
relevance of circulating lactate or other metabolic inte
24 The
relevance of citations was assessed based on inclusion c
25 man retinal tissues confirmed the biological
relevance of CL-11.
26 In this review, we illustrate the
relevance of cooperative interactions in microbial biote
27 rimary sensitizing allergen and the clinical
relevance of cross-sensitization, we correlated sensitiz
28 tro and in vivo techniques, and the clinical
relevance of CXCR4 and CXCR2 expression was studied in g
29 ain elusive, prompting us to investigate the
relevance of CXCR4 in vascular cell types for atheroprot
30 This highlights the
relevance of degradation processes.
31 ing models of the disease and highlights the
relevance of desmoglein-specific versus nondesmoglein au
32 ntaminated leaves, our results emphasize the
relevance of dietary exposure (e.g., via leaves) for sys
33 by text mining to evaluate functional marker
relevance of discovered genes.
34 Systematic debate on the
relevance of distinct imaging modalities held in 2 conse
35 erin interactions and support the functional
relevance of dockerin classification into groups.
36 amine the physiological basis and behavioral
relevance of driving beta and gamma oscillatory activity
37 While the importance and
relevance of each lesson will vary by context, there is
38 The
relevance of each of these themes to current clinical pr
39 hasize the clinical and public health policy
relevance of early life PM2.5 exposure.
40 cognitive decline, highlighting the clinical
relevance of early recognition and treatment.
41 lar histones, suggesting a possible clinical
relevance of elevated histones in pulmonary injury.
42 Our data support the
relevance of enhancing mitochondrial proteostasis to del
43 Here, we report prognostic
relevance of EVI1 overexpression in triple-negative brea
44 on in amphibians and highlight the potential
relevance of fluorescence in visual perception in terres
45 Our data uncover the physiopathological
relevance of fork reversal and illuminate a complex inte
46 s study investigates the nature and clinical
relevance of GA101-mediated trogocytosis.
47 Together, these results indicate that the
relevance of GABAergic inputs from AgRP to POMC neurons
48 osis (MS); however, the potential biological
relevance of GALC variants to MS remains elusive.
49 To validate the in vivo
relevance of genetic dependencies observed in human cell
50 However, the
relevance of germline variants in other genes from multi
51 Virtually nothing is known about the
relevance of glycolysis in patients with allergic asthma
52 e tracheal epithelial cells, to evaluate the
relevance of glycolysis.
53 of the fundamental understanding and applied
relevance of halogen chemistry in polymer industries (po
54 e use transgenic lines to define the in vivo
relevance of HDAC1 and identify calcineurin-dependent se
55 d in other recent reviews; these include the
relevance of herpes simplex encephalitis and of epilepsy
56 ism of tau, and more broadly underscores the
relevance of heterogeneous and dynamic complexes in the
57 rsive-partitioning analyses demonstrated the
relevance of Hg stable isotopes as discriminating tools.
58 elps to better understand the motor clinical
relevance of hypermetabolic brain regions in HD.
59 y in AD individuals) to assess the clinical
relevance of identified risk haplotypes.
60 Given the emerging
relevance of immunotherapies that boost pre-existing T c
61 ity in acute HF, thus, supporting functional
relevance of impaired CgA processing in cardiovascular d
62 This paper aims to evaluate the
relevance of including maas as a traditional food produc
63 Our model jointly estimates the
relevance of individual factors, refines gene set annota
64 However, the
relevance of individual residential changes and their im
65 526 526 References 526 The
relevance of infochemicals in the relationships between
66 Our data highlight the
relevance of innate immunity and, especially, the tight
67 , to strengthen the uptake and international
relevance of IPC interventions.
68 Given the translational
relevance of LAG3 and the heightened interest in the imp
69 owever, both the mechanism and physiological
relevance of LGR5 internalization are unclear.
70 We then tested the physiological
relevance of LGR5 internalization blockade in vivo A LGR
71 opportunity to illuminate the physiological
relevance of lipid peroxyl radical production during cel
72 Given the
relevance of lungfishes in evolutionary terms, the prese
73 s animal model and highlighting the clinical
relevance of lymphangiogenesis in corneal fluid homeosta
74 To investigate the
relevance of lymphangiogenic gene expression in primary
75 he importance of transient dynamics, and the
relevance of manipulating a cascade of destabilizatons f
76 on approaches for investigating the role and
relevance of MCs in various diseases.
77 These data cast serious doubt on the
relevance of measuring urinary iodide concentration to e
78 Despite the well-established
relevance of mechanical cues to cell behavior and the nu
79 in type 2 diabetes raises the translational
relevance of mechanisms that direct and maintain beta ce
80 However, the
relevance of menaquinones produced by gut bacteria to vi
81 strategies for determining the true clinical
relevance of metabolites observed in association with ca
82 ntially conditional APCs, but the functional
relevance of MHC-II expression by Schwann cells has not
83 the mechanistic implementation and clinical
relevance of microbiome alterations on disease susceptib
84 This perspective highlights the
relevance of micropipette-aspirated single-particle trac
85 irmed model-based predictions on the limited
relevance of microplastic for bioaccumulation under envi
86 induces oxidant stress in vitro However, the
relevance of MIOX to tubular pathobiology remains enigma
87 To address the in vivo
relevance of miR-34a/b/c function for suppression of int
88 In addition, we discuss the
relevance of mitochondrial targeted treatments to mental
89 These findings highlight the
relevance of MLL2 as a drug target in MLL-rearranged leu
90 On the basis of this new insight into the
relevance of MMP-10 and MMP-13 within the MMP network an
91 Our results corroborate the
relevance of MNDCMs in heart regeneration.
92 We also investigate the clinical
relevance of MOG-IgG through a longitudinal analysis of
93 to investigate the expression and functional
relevance of MS channels in human platelets.
94 To understand the functional
relevance of mTOR enzymatic activity in beta-cell develo
95 These data demonstrate the
relevance of Nbeal2 in mast cells above and beyond granu
96 Here, we discuss the biological and clinical
relevance of negative and positive signaling modalities
97 We further established the in vivo
relevance of NETs and the requirement of RIPK1/3/MLKL-de
98 To test the physiological
relevance of noncanonical TR signaling, we generated kno
99 y code, and to investigate the developmental
relevance of noncoding transcription, we compared genome
100 tic and expression data revealed the disease
relevance of NPAS-regulated genes and pathways.
101 In order to understand the mechanistic
relevance of Nrf2 as a marker of drug-induced stress it
102 tion for articles on prevalence and clinical
relevance of NTM detection in pulmonary samples in sub-S
103 tudies may be useful to explore the clinical
relevance of off-target drug effects.
104 ncer patients further validated the clinical
relevance of our finding.
105 f a cohort of different cancers supports the
relevance of our findings for tumor biology.
106 We discuss the possible
relevance of our findings to the mechanism of trehalose
107 Cell-based assay supports the physiological
relevance of our findings.
108 ession in the latter, supporting the in vivo
relevance of our findings.
109 re highly expressed, supporting the clinical
relevance of our observations in mice.
110 The potential
relevance of our observations is supported by the down-r
111 We discuss the
relevance of our results in the light of recent experime
112 The physiological
relevance of our technique was demonstrated using salini
113 y "metric" for determining the technological
relevance of oxide-based anodic water electrolyzer catal
114 Two reviewers assessed the
relevance of papers based on the inclusion criteria.
115 e's Chief Editor Larry Peiperl discusses the
relevance of patient care to a journal editor's work.
116 These data indicate the
relevance of pBNST activity for adaptive stress recovery
117 To study the
relevance of pericardial clusters during inflammatory re
118 The aim of this study was to evaluate the
relevance of PET/CT and (18)F-FDG as a strategy for resp
119 ing field of photopharmacology indicates the
relevance of photocontrol in future medicine.
120 ideas stressing the multifaceted biological
relevance of phytoplankton chytridiomycosis, resulting f
121 The
relevance of polar effects is supported by theoretical c
122 The clinical
relevance of PPARalpha and its biological function in pa
123 Finally, we demonstrated the
relevance of predicted EMT scores to patient survival an
124 tions hamper the interpretation and clinical
relevance of previous studies.
125 ue of LumC13 (Lumikine) and aid its clinical
relevance of promoting the healing of corneal epithelium
126 Until now, the physiological
relevance of PRR2 remained largely unknown.
127 The clinical
relevance of RAGE in inflammatory disease is being demon
128 This highlights the clinical
relevance of reducing ICH by using apixaban rather than
129 However, the prognostic
relevance of remnant liver ischemia (RLI) after resectio
130 efficiency of these clusters emphasizes the
relevance of reorganization energy in this process.
131 Our results emphasize the clinical
relevance of reporting diffuse ptc, which may relate to
132 The aim of the study was to assess the
relevance of resection margin status for survival after
133 To assess the
relevance of resection margin status for survival outcom
134 the human brain, demonstrating the cognitive
relevance of resting-state network topology.
135 These data provide new insights into the
relevance of RNA pseudouridylation in mitochondrial gene
136 displays strong conservation, the functional
relevance of SD-aSD interactions in plastid translation
137 Our findings reveal the
relevance of SEIPIN-dependent LD biogenesis in pollen tr
138 Through a targeted RNAi screen examining the
relevance of selected TRIM proteins in autophagy induced
139 The clinical
relevance of sensitization was demonstrated by specific
140 The clinical
relevance of SERS is proved by its application for the d
141 ng in their regimes of applicability, in the
relevance of signals to be encoded, and in the choice of
142 Altogether, these results show the
relevance of single arabinose residues, present at the n
143 To address the
relevance of small non-coding RNAs in SARS-CoV pathology
144 the pupal nervous system and emphasizes the
relevance of SOCE-regulated gene expression to flight ci
145 accumulation is of key importance, given the
relevance of soil organic matter (SOM) as a vast C pool
146 tomo-seq, we were able to unveil the unknown
relevance of SOX9 as a key regulator of cardiac fibrosis
147 al predictability of visual targets, and the
relevance of spatial/temporal information provided by au
148 However, the
relevance of specific reaction elementary steps to the o
149 These findings underscore the potential
relevance of spinel-type oxides as p-type transparent co
150 different in Arabidopsis, and the functional
relevance of STM mobility is unknown.
151 The physiological
relevance of structures within mammalian mRNAs has been
152 ues among clinicians as to both the clinical
relevance of subclinical BPV thrombosis and the value of
153 tunities, but the prevalence and therapeutic
relevance of such effects (gain of function and dominant
154 als (CD) is not well understood, despite the
relevance of such effects to long-term outcomes.
155 s global diversity of these viruses, and the
relevance of such for development of pharmaceutical inte
156 e on animal population dynamics, despite the
relevance of such information for conservation.
157 wever, the underlying mechanisms and disease
relevance of such lysosome accumulations are not well un
158 e molecules and investigating the diagnostic
relevance of such molecules in childhood.
159 easonable and necessary that we question the
relevance of such small effects, we present examples in
160 olone, was used as a criterion to assess the
relevance of SUCNR1/GPR91 expression mediating allergic
161 These findings emphasize the
relevance of sufficient intrauterine oxygenation for nor
162 superoxide inhibitors proving the functional
relevance of superoxide release for HPV.
163 Overall, the present work highlights the
relevance of T2 as a key bioactive hormone, and reveals
164 These results highlight the
relevance of the 8 kDa domain of Polmu for accurate and
165 stic models, putting constraints on physical
relevance of the abstract models.
166 allergic conjunctivitis, especially when the
relevance of the allergen is not obvious or in polysensi
167 he case study, we show the higher biological
relevance of the biomarkers selected by our approach.
168 We analyze the
relevance of the CaFADS head-to-tail macromolecular inte
169 To examine the biological
relevance of the capsid interactome, we modulated the ex
170 Given the known clinical
relevance of the CD73/adenosine pathway in several solid
171 However, the
relevance of the cellular mechanisms identified in vitro
172 esticated birds is largely untested, and the
relevance of the chicken as an ecological model is uncer
173 These results highlight the
relevance of the colony biofilm model to pathogenicity a
174 ene expression, supporting the physiological
relevance of the concept of diapause phasing.
175 The functional
relevance of the conformational dynamics observed in the
176 ynamics will permit assessing the functional
relevance of the detected changes to the progression and
177 y to AD, the action of IFN, and the possible
relevance of the different types of DNA damage to AD-in
178 These findings highlight the
relevance of the DNA-sensing mechanism in the detection
179 The functional
relevance of the gut mycobiome was confirmed in fecal tr
180 t as a case study, we look at the biological
relevance of the identified biomarkers.
181 ltiradiene is the relevant precursor and the
relevance of the identified diterpene synthases, enablin
182 e the time required to assess the biological
relevance of the IgG microheterogeneities thus providing
183 function has been reported, but the in vivo
relevance of the in vitro observations is still unclear.
184 nd propose its application for assessing the
relevance of the in vitro positive results to carcinogen
185 The functional
relevance of the innate immune system has not yet been d
186 The
relevance of the innate immune system, and monocytes in
187 n this study, we investigated the biological
relevance of the interaction between ICP34.5 and TANK-bi
188 The functional
relevance of the inverted repeat structure (IR/DR) in a
189 To confirm the physiologic
relevance of the MAP17-SGLT2 interaction, we studied a c
190 The
relevance of the multi-parameter electrochemical data fo
191 We also examine the biological
relevance of the network profiles.
192 The clinical
relevance of the newly characterized AKT1 VNTR merits in
193 The functional
relevance of the observed motional quenching is confirme
194 tractant serine, pointing to a physiological
relevance of the observed thermotactic behavior.
195 active in the basal state and the functional
relevance of the observed tonic signaling heterogeneity
196 an oscillator and explored the physiological
relevance of the oscillator structure for accurately tim
197 sults indicate an increasing epidemiological
relevance of the pathogen and the need for in-depth inve
198 The
relevance of the pericardial AT in mediating all these e
199 The biological
relevance of the present method has been demonstrated by
200 Finally, to test the pharmacodynamic
relevance of the proposed biomarker, two anti-epileptoge
201 The practical
relevance of the proposed method is that it provides an
202 excitatory synaptic function, we address the
relevance of the proteolytic processing of presynaptic n
203 of thiols with low pKa values emphasizes the
relevance of the protonation step in the ring-opening re
204 The results support the physiological
relevance of the rat mesentery culture model as a biomim
205 esults also underline the seminal biological
relevance of the regulation of electron transport reacti
206 Our data indicate the
relevance of the remaining thymic function before the st
207 The clinical
relevance of the result was confirmed by the significant
208 Biological
relevance of the resulting models, as quantified via a l
209 ds has been taken as evidence of the limited
relevance of the results.
210 regulator of ESR1 and revealed the clinical
relevance of the RNA-binding protein MSI2 in breast canc
211 n cancer and metabolism have highlighted the
relevance of the serine synthetic pathway (SSP), which c
212 mary visual cortex depends on the behavioral
relevance of the stimulus.
213 results, together with the known functional
relevance of the three genes to LMI, suggested that the
214 lopments in this field that support a strong
relevance of the UPR to many areas of plant life.
215 merous important functions in plants but the
relevance of their complex structure to physiological fu
216 onic substrate, and confirmed the functional
relevance of these amino acids using a targeted mutagene
217 arnered considerable attention, the clinical
relevance of these associations remains to be determined
218 ns involved in this disease and the clinical
relevance of these autoimmune responses are still being
219 To determine the functional
relevance of these bioactive THs, RNA-seq analysis was c
220 ing the cut-offs may increase the diagnostic
relevance of these biomarkers, particularly for APRI and
221 Furthermore, we confirm the clinical
relevance of these cells by demonstrating a direct corre
222 However, the clinical
relevance of these events is uncertain.
223 de axonal damage in culture, but the in vivo
relevance of these findings and the potential posttransl
224 The
relevance of these findings and their possible physiolog
225 We confirmed the clinical
relevance of these findings by showing that human Tregs
226 with psychiatric disorders, and explore the
relevance of these findings for future treatment strateg
227 The translational
relevance of these findings is highlighted by the higher
228 The
relevance of these findings relative to visual acuity, h
229 To determine the
relevance of these findings to bone homeostasis, we stud
230 apsaicin treatment demonstrates the clinical
relevance of these findings.
231 The
relevance of these genes is supported by the eQTL analys
232 The
relevance of these genes/isoforms to HCC are supported b
233 nally, we provide a brief perspective on the
relevance of these interconnections for natural selectio
234 The
relevance of these issues was already recognized in the
235 27 di- and trimethylation (H3K27me2/3), the
relevance of these mutations has not been studied in acu
236 The
relevance of these observations has been extended using
237 However, the physiological
relevance of these observations to adult ovarian functio
238 The
relevance of these observations with respect to systems
239 communication in microalgae, because of the
relevance of these organisms for global primary producti
240 mortality, and determined if the prognostic
relevance of these parameters was affected by their temp
241 rs and infections, suggesting an unpredicted
relevance of these peculiar peptides.
242 patients with CF supported the translational
relevance of these preclinical findings.
243 odelling and angiogenesis, suggesting a high
relevance of these processes for the pathogenic mechanis
244 s, topographical organization and perceptual
relevance of these representations.
245 rom an application-oriented perspective, the
relevance of these results hinges on the possibility to
246 is an ongoing debate about the physiological
relevance of these stress-induced pHapo changes.
247 ssion analysis has allowed us to confirm the
relevance of these targets for EOC and further provided
248 these loci, and the clinical and functional
relevance of these variants should be pursued.
249 The
relevance of these waves for visual processing is unknow
250 However, the
relevance of this activity in vivo has remained elusive.
251 To assess the clinical
relevance of this ADAM17-mediated ACE2 shedding in hyper
252 espite evidence supporting the translational
relevance of this approach, relatively few studies have
253 HA-specific inhibitors, indicating the high
relevance of this cavity for drug design.
254 The
relevance of this chemistry in the oxidation of organics
255 ion of the MET extracellular domain, and the
relevance of this conformation to HGF/SF binding and sig
256 However, the physiological
relevance of this discovery remained unclear, as we were
257 The
relevance of this diversity to maintain self-tolerance r
258 We discuss the potential
relevance of this dual chemoreceptor feedback to cardior
259 In this work, we have checked the biological
relevance of this finding by analyzing WT plants under h
260 Because the disease
relevance of this finding is evident, additional studies
261 To test the physiological
relevance of this hypothesis, we first showed that macro
262 Munc18-1 binds to synaptobrevin, but the
relevance of this interaction and its relation to Munc13
263 active protein (CRP), analyze the functional
relevance of this interaction, and study the role of FHR
264 To define the physiologic
relevance of this loop, melanoma cells with different Wn
265 dothelial hyperproliferation, supporting the
relevance of this mechanism in vivo.
266 resistance arteries supported the biological
relevance of this mechanism.
267 and little is known about the environmental
relevance of this metabolism.
268 provide evidence to establish the functional
relevance of this newly discovered regulatory axis in TN
269 Many aspects of the regulatory
relevance of this pathway have been investigated in immu
270 Furthermore, we confirm the in vivo
relevance of this pathway in our IL-15 transgenic mouse
271 However, the genetic
relevance of this pathway to aggressive prostate cancer
272 the potential mechanistic and translational
relevance of this pathway to CTRCD.
273 sphotyrosine phosphatase 1B (PTP1B), and the
relevance of this pathway to VEGF-induced angiogenesis,
274 cohorts are needed to establish the clinical
relevance of this phenomenon and differentiate between v
275 Collectively, our data support the clinical
relevance of this protease in human influenza pathogenes
276 n urine provided evidence for the biological
relevance of this reaction.
277 Relevance of this regulatory strategy is confirmed in vi
278 However, the functional
relevance of this strong collecting duct epithelial barr
279 To probe the behavioral
relevance of this suppression, we examined whether the s
280 nderlying molecular mechanism and biological
relevance of this targeting of Axin have not been elucid
281 s, healthy volunteers, and patients, yet the
relevance of this to pharmacotherapeutic actions remains
282 The
relevance of this U-turn is associated with transcriptio
283 g of puberty in animal models, but the human
relevance of those findings is unknown.
284 This work establishes the
relevance of thymic function, measured by sj/beta-TREC r
285 patch clamp recordings, we investigated the
relevance of TMEM16F activation for several bioeffects t
286 f different pluripotent states, and show the
relevance of transitions between these states during dev
287 e outcome set to improve the consistency and
relevance of trials in kidney transplantation.
288 ngs support the potential pathophysiological
relevance of TRX in celiac disease and establish the Cys
289 e used a genetic approach to distinguish the
relevance of two distinct components of this pathway, ap
290 Our findings validate the
relevance of two original models of the mechanisms of am
291 emperature and pressure is reported, and the
relevance of ultrasound absorption in acoustic investiga
292 The
relevance of UMOD for CKD is clear, because the encoded
293 rge clones, underscoring the feasibility and
relevance of understanding drivers of the differences.
294 Here we address the
relevance of using a specific Anopheles salivary biomark
295 olution and the meat sample highlighting the
relevance of using physiological conditions for accurate
296 ATPase and to fully evaluate the therapeutic
relevance of V-ATPase in human diseases.
297 The
relevance of vapor driven entrainment of metal micro-par
298 These results demonstrate the behavioral
relevance of variability in brain responses to aversive
299 in visual cortex can reflect the behavioral
relevance of visual information.
300 al cognitive domains highlights the clinical
relevance of white matter damage in this disorder and wa