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1 e relationship to local circuit architecture remains unclear.
2                However, its central function remains unclear.
3 ific variation in embryonic development time remains unclear.
4 eneration, the underlying mechanism of which remains unclear.
5  these cells participate in memory retrieval remains unclear.
6 lated by region-specific molecular mechanism remains unclear.
7 ut the impact of specific platelet receptors remains unclear.
8 parated interlayers through a mechanism that remains unclear.
9 to enrich isobarically labeled glycopeptides remains unclear.
10  However, its precise mechanism(s) of action remains unclear.
11 r effect on the surface electronic structure remains unclear.
12 wever, the role of this cascade in human HCC remains unclear.
13 er, the mechanism underlying this resistance remains unclear.
14 omes in coronary artery bypass graft surgery remains unclear.
15 hanism functions in multicellular eukaryotes remains unclear.
16 ation between rs1137070 and heroin addiction remains unclear.
17 hough the causal nature of this relationship remains unclear.
18 e precise role of ZNF750 in SCC cell biology remains unclear.
19 DHD medication treatment on the risk of MVCs remains unclear.
20 he spatiotemporal distribution of GA in vivo remains unclear.
21 atic melanoma, yet their mechanism of action remains unclear.
22 ntified >130 years ago, its neural mechanism remains unclear.
23 w genotoxicity-induced HF injury is repaired remains unclear.
24 , how calpain regulates growth cone motility remains unclear.
25 ownstream mechanism of CXCR7 in angiogenesis remains unclear.
26 nduced endothelial proinflammatory responses remains unclear.
27 isoforms influence AD pathogenesis, however, remains unclear.
28 ionship between spine plasticity and craving remains unclear.
29 ansdiagnostic feature of psychiatric illness remains unclear.
30      But how intasome assembly is controlled remains unclear.
31 their contribution to ZIKV infection in vivo remains unclear.
32 ous mechanisms operate in these compartments remains unclear.
33                         Mode of transmission remains unclear.
34  (PTB) or extrapulmonary (EPTB) tuberculosis remains unclear.
35 s protease is post-translationally regulated remains unclear.
36 ism underlying the disrupting effect of KYNA remains unclear.
37  the underlying neurodevelopmental processes remains unclear.
38 al communities but their relative importance remains unclear.
39 wever, the precise mechanism of this process remains unclear.
40 g colon tumorigenesis and cancer progression remains unclear.
41 s or whether it also mediates memory storage remains unclear.
42 nzymes localize to their target genomic loci remains unclear.
43 nts, the mechanism of action of these agents remains unclear.
44 egulate the termination of granule secretion remains unclear.
45 kers and children living in their households remains unclear.
46 by [Hb] measurements and clinical correlates remains unclear.
47 llostery in the absence of structural change remains unclear.
48 -related factors limit growth during drought remains unclear.
49 hysiological role of SID-1 and its orthologs remains unclear.
50 nactive X chromosome (Xi) and spreads in cis remains unclear.
51 e contribution of epistasis to human disease remains unclear.
52  of most human long noncoding RNAs (lncRNAs) remains unclear.
53  autologous adipose-derived adult stem cells remains unclear.
54 er of cases defining a "high-volume" surgeon remains unclear.
55 he specific antipruritic mechanism of action remains unclear.
56 (ABA) but whose molecular and cellular basis remains unclear.
57 l role in organisms without a nervous system remains unclear.
58 depend on the GC receptor (GR) in adipocytes remains unclear.
59 ion on deforestation in oil palm plantations remains unclear.
60 +) induces the recruitment of AMPA receptors remains unclear.
61  the best strategy to prevent these episodes remains unclear.
62 he contribution of RCrusI dysfunction to ASD remains unclear.
63 IRAK-1, whereas the role of IRAK-1 in humans remains unclear.
64 center volume on pancreas allograft survival remains unclear.
65 regulating FLT3-ITD-mediated disease in vivo remains unclear.
66 ction with manifestations of atherosclerosis remains unclear.
67 cular level, but their biological importance remains unclear.
68 s conduction defect, DCM, and heart failure, remains unclear.
69 o phenotypic differences between ethnicities remains unclear.
70 nction of 5-LO in the tumor microenvironment remains unclear.
71  for the symptoms of schizophrenia, however, remains unclear.
72 erlying this synergy within NK cell clusters remains unclear.
73 elopment of ALS and survival after diagnosis remains unclear.
74 mplexity that characterizes eukaryotic cells remains unclear.
75 injury (ICI) on computed tomographic imaging remains unclear.
76 A responsible for the proinflammatory effect remains unclear.
77 gfr and Hedgehog signals to drive overgrowth remains unclear.
78 l CESA proteins are organized within the CSC remains unclear.
79  AMPAR-mediated signaling in the spinal cord remains unclear.
80 m underlying 4E-BP1 downregulation in tumors remains unclear.
81 ytic metabolism influences metastasis in HCC remains unclear.
82 er, the mechanism of the misfolding reaction remains unclear.
83               The regulation of CPC function remains unclear.
84 approach in this evolving patient population remains unclear.
85 aiting heart transplantation, and the reason remains unclear.
86 o modulate cochlear implant (CI) performance remains unclear.
87 res, which also derive from organ primordia, remains unclear.
88 physiological adaptation to oxidative stress remains unclear.
89 stent and the role of WT1 in this malignancy remains unclear.
90 te or other metabolic intermediates as fuels remains unclear.
91  soils across environmental conditions still remains unclear.
92 t their relative contribution to HIV control remains unclear.
93 dators, but how their influences may combine remains unclear.
94  as well as the regulation of N-fucosylation remains unclear.
95  severity range in patients with acute mania remains unclear.
96 o the oncometabolic state of prostate cancer remains unclear.
97 heir impact on BBB integrity during ischemia remains unclear.
98 scular function, microvascular permeability, remains unclear.
99 echanism behind this differentiation process remains unclear.
100 are confounded with phylogenetic structuring remains unclear.
101 ti-depressive function for prolonged periods remains unclear.
102 tic histone marks are mechanistically linked remains unclear.
103  recruiting different ratios of E-to-I cells remains unclear.
104 ility, but whether they regulate axon growth remains unclear.
105 nderlie ATM regulation of energy homeostasis remains unclear.
106 to construct such versatile receptive fields remains unclear.
107 ft ventricular assist device (LVAD) patients remains unclear.
108  activation are regulated during development remains unclear.
109 nfection, but their influence on CD4 T cells remains unclear.
110 d factors on neurotransplantation strategies remains unclear.
111 rity of the immune system, but the mechanism remains unclear.
112 o nevertheless initiate protective responses remains unclear.
113 pathy but the underlying molecular mechanism remains unclear.
114 er, the exact underlying mechanism of action remains unclear.
115 phorylation at the Ser-31 site (THSer(P)-31) remains unclear.
116 nging seasonal distribution of precipitation remains unclear.
117 anding of injury-induced synaptic remodeling remains unclear.
118 ral activity dynamics in prefrontal networks remains unclear.
119 ctly perturbs the DNA replication checkpoint remains unclear.
120  but its existence over the most recent past remains unclear.
121  role of other IL-17 cytokine family members remains unclear.
122 ormalities, its precise molecular regulation remains unclear.
123 ) and age-related macular degeneration (AMD) remains unclear.
124 stimuli may be behaviorally relevant or not, remains unclear.
125 landscape of primary mucosal melanomas (PMM) remains unclear.
126 s that contribute to separate brain networks remains unclear.
127 lying mechanism for the observed enhancement remains unclear.
128 a different prevalence and prognostic impact remains unclear.
129 dala participates in such a learning process remains unclear.
130 CPC interactions with other mitotic proteins remains unclear.
131 action (OER) catalysts, yet its precise role remains unclear.
132 llance colonoscopy on colorectal cancer risk remains unclear.
133 renal tubules regulate capillary development remains unclear.
134 in brown fat; however, its role in beige fat remains unclear.
135 re sustained in chronically inflamed tissues remains unclear.
136 d within the dendrites of individual neurons remains unclear.
137  of circulating antibodies before transplant remains unclear.
138 s, although the adequate duration of therapy remains unclear.
139 n structured changes to inhibitory circuitry remains unclear.
140 es that provide ecosystem services to humans remains unclear.
141 t the transcriptional basis of this response remains unclear.
142 ), while the underlying biological mechanism remains unclear.
143                     How this bypass operates remains unclear.
144 lineages, but how Zbtb16 itself is regulated remains unclear.
145 e phenomena affect cortical circuit activity remains unclear.
146 effectors reprogram the cytoskeleton network remains unclear.
147  by which NO modulates corneal wound healing remains unclear.
148  AMPAR-mediated signaling in the spinal cord remains unclear.
149 nce, the mechanism(s) underlying this defect remains unclear.
150 tion to type 2 diabetes (T2D) in the elderly remains unclear.
151 egulation of these complex dynamics in cells remains unclear.
152 of SIRT5 in organismal metabolic homeostasis remains unclear.
153 es of gene flow within microbial communities remains unclear.
154 issues, yet its role in auditory development remains unclear.
155 n response to changes in these contingencies remains unclear.
156  as a consequence of neuroinfectious disease remains unclear.
157 eptor activation and intracellular signaling remains unclear.
158 naling in the regulation of PD-L1 expression remains unclear.
159 wth is terminated after reaching proper size remains unclear.
160 rrangement of cis-regulatory elements (CREs) remains unclear.
161 cular in vivo systems overcome the challenge remains unclear.
162 nal sub-domain, termed IIId2, whose function remains unclear.
163 t of DNA methylation reprogramming in plants remains unclear.
164 to DNA damage and chemotherapeutic treatment remains unclear.
165 rning the maladaptive persistence of anxiety remains unclear.
166 oteins, its biological function in the brain remains unclear.
167 wever, its ability to regulate reinnervation remains unclear.
168 ver, the regulation of methionine metabolism remains unclear.
169 ng pathway, although its mechanism of action remains unclear.
170 e plasticity of endogenous pericytes in vivo remains unclear.
171 l infarction (MI)-induced cardiac remodeling remains unclear.
172 nked to large igneous provinces, its trigger remains unclear.
173 ve been found, but the function of these has remained unclear.
174 phorylation in virion secretion, if any, has remained unclear.
175 move in a directed and collective manner has remained unclear.
176 timulated genes (ISGs) in infected monocytes remained unclear.
177 ence but its magmatic and uplift history has remained unclear.
178 e GIPC/cargo and GIPC/myosin VI interactions remained unclear.
179 mechanisms that govern this selectivity have remained unclear.
180  and induces its perinuclear trafficking has remained unclear.
181                                The mechanism remained unclear.
182 n replicate in vivo via mechanisms that have remained unclear.
183 rinsic, direct regulation of lymphocyte fate remained unclear.
184 relevance, the evolutionary origin of USA300 remained unclear.
185 ts the PIC, especially post-recruitment, has remained unclear.
186 sal polymorphism of the domestication traits remained unclear.
187 rapped and the sequestration mechanisms have remained unclear.
188 GICs mass loss and the acting processes have remained unclear.
189 ance of these lesions in ALL has, until now, remained unclear.
190 , but the underlying mechanisms of this have remained unclear.
191 w hPOT1 mutations initiate tumorigenesis has remained unclear.
192 signaling events are interconnected has long remained unclear.
193 ase (TCP) responsible for detyrosination has remained unclear.
194    However, the exact mode of action of Red1 remains unclear, although it is known to interact with H
195  skin as a source of infection to sand flies remains unclear, and the possible effect of multiple exp
196 he physiological relevance of this discovery remained unclear, as we were unable to identify a functi
197 rossover formation actually energizes fusion remains unclear, as do the sequence of events surroundin
198               The mechanism of this conflict remains unclear, besides the anticipated accumulation of
199                      The function of C1QTNF5 remains unclear but this new insight into the pathogenet
200 e role of alternative splicing in beta cells remains unclear, but recent data indicate that splicing
201  herein identified eukaryotic d-ribulokinase remains unclear, but we speculate that S. cerevisiae Ydr
202                    While its biological role remains unclear, crystal structure analyses and biochemi
203  pathway by which this reaction proceeds has remained unclear for several decades.
204 l variants lead to altered disease risk have remained unclear for the majority of these loci.
205                                  However, it remained unclear how cryptochromes regulate the BIC gene
206 sions predominantly originate prenatally, it remains unclear how and when exactly MCT8 dysfunction af
207                                      It also remains unclear how cells behave during the demarcation
208                                  However, it remains unclear how ChlF and photosynthesis are linked a
209          Despite two decades of research, it remains unclear how dopamine neurons make this calculati
210 ve helped define human NP cell phenotype, it remains unclear how expression of these markers is influ
211 often implicated in the illness, although it remains unclear how functional alterations of the region
212                                           It remains unclear how history of adaptation to one antibio
213                                  However, it remains unclear how infection initially becomes latent.
214                                  However, it remains unclear how intercellular signaling among somati
215 rcuits underlying motivated behavior, but it remains unclear how its inputs from different sources in
216                                  However, it remains unclear how LAP shapes both the activation and o
217 n states have been studied for some time, it remains unclear how large-scale cortico-cortical functio
218  about the underlying signaling pathways, it remains unclear how macroscopic features of branched org
219 ed proteins can be found in mitochondria, it remains unclear how mitochondrial dysfunction and protei
220                                  However, it remains unclear how naive T cells survive for years whil
221 actory responses to pulses and steps, but it remains unclear how olfactory receptor neurons (ORNs) de
222 BP) formation in finished water; however, it remains unclear how quality and quantity of overall allo
223                                           It remains unclear how RICD sensitivity is calibrated in T
224 idence of sudden changes in behavior, but it remains unclear how such epiphanies occur.
225 0 is also expressed on activated T cells, it remains unclear how T cell-derived CD70 affects T cell f
226                             Particularly, it remains unclear how the cascade components collectively
227                                  However, it remains unclear how the coordinated behaviour of cytoske
228                                  However, it remains unclear how the Hsp70 conformational ensemble is
229                                  However, it remains unclear how these approaches compare when applie
230                                  However, it remains unclear how these FMRP activities relate to each
231 K control distinct pools of cellular SFs, it remains unclear how these kinases differ in their regula
232 een implicated in lineage allocation, but it remains unclear how these processes are coordinated.
233                                      It also remains unclear how translational heterogeneity originat
234                                           It remains unclear how Treg cells orchestrate their homeost
235                        In many organisms, it remains unclear how X chromosomes are specified for dosa
236     The most appropriate disinfection method remains unclear, however, and it is likely that replacem
237                                           It remains unclear, however, what mechanism initiates forma
238                                           It remains unclear, however, whether the molecular events d
239 cholinergic input to the main olfactory bulb remains unclear, however.
240               In addition, the genetic cause remains unclear in approximately 25%-30% of individuals
241                                         What remains unclear is whether PAR1 activation also regulate
242                         The current evidence remains unclear on the potential role of pharmacogenomic
243            The pathogenesis of severe dengue remains unclear, particularly the mechanisms underlying
244  molecules of kinesin along microtubules has remained unclear, partly because available structural me
245 ventional treatments impact on immune system remains unclear, proper integration is still a challenge
246 ical systems (e.g., earthquakes), and yet it remains unclear the extent to which ecological populatio
247                                           It remains unclear to what degree, if any, BV uses chemical
248                             Consequently, it remains unclear to what extent robust stress-induced DNA
249  and glycemic load (GL) value determinations remains unclear.We determined the effect of meals that v
250 ion, yet the relation with clinical outcomes remains unclear.We evaluated AT transcriptome alteration
251 dancy and regulatory flexibility, but it has remained unclear what signal-processing capabilities it
252 at coat our teeth impact oral health, but it remains unclear what factors govern their composition.
253                                  However, it remains unclear what mechanisms could be responsible for
254 rupted after chronic drug abuse; however, it remains unclear what neural signals in DLS are altered.
255 (vPFC) are linked with trait anxiety, but it remains unclear what potential genetic moderators contri
256 9,000 calendar years B.P. (cal B.P.), but it remains unclear when maize was productive enough to be a
257 ed by the plant hormone ethylene, but it has remained unclear whether and how its biosynthesis is reg
258                              However, it has remained unclear whether endogenous KLF4 and Krox20 are
259                              However, it has remained unclear whether GR is required for adipogenesis
260 g system, soybean lipoxygenase (SLO), it has remained unclear whether the requisite close tunneling d
261                                     Thus, it remained unclear whether transmembrane PrP(C) might conv
262                                           It remains unclear whether and how connectivity in various
263                                  However, it remains unclear whether bone regions typically targeted
264                                  However, it remains unclear whether bSi with the nanopillars can kil
265                                           It remains unclear whether endogenous sex hormones (ESH) ar
266 mall RNAs in hybrid performance; however, it remains unclear whether epigenetic changes are a cause o
267                                  However, it remains unclear whether exposure to a previous pandemic
268 y consequences are nearly unknown because it remains unclear whether frugivores exert strong selectio
269                                           It remains unclear whether ischemic risk and the benefits o
270 line stem cells (GSCs) and early progeny, it remains unclear whether it plays any roles in early GSC
271      However, elsewhere in visual cortex, it remains unclear whether M-P-derived information (1) beco
272                                  However, it remains unclear whether MSA exerts its effects on cancer
273                                      It also remains unclear whether mu rhythm suppression during act
274                                  However, it remains unclear whether novel mcrA genes associated with
275                                           It remains unclear whether radial access (RA), compared wit
276                                           It remains unclear whether revascularization by either coro
277                                  However, it remains unclear whether RFOs have a role in establishing
278                                           It remains unclear whether the adjusted odds of survival ha
279                                  However, it remains unclear whether the association between GABA lev
280 e heterogeneity among our reported cases, it remains unclear whether the DEX endophthalmitis rate app
281                                  However, it remains unclear whether the loss of miRNA processing and
282                             Nevertheless, it remains unclear whether the minimal treatment response t
283                                  However, it remains unclear whether these cases truly represent sexu
284                                  However, it remains unclear whether these ligands have effects on AH
285                                           It remains unclear whether these two feelings can be accura
286 tails the duration of AHR signalling, but it remains unclear whether they also regulate AHR ligand av
287                                           It remains unclear whether this effect operates through an
288                                  However, it remains unclear whether this principle generalizes to sp
289                                  However, it remains unclear whether this recurrent amplification is
290                                           It remains unclear whether, in addition to their cytolytic
291 espiratory infection in infants; however, it remains unclear which infants with bronchiolitis will de
292                                  However, it remains unclear which macroscopic signal is related to t
293                                           It remains unclear which strategy is most attractive for cl
294 ly or on demand) and oral antihistamines, it remains unclear which treatment provides the best relief
295 ted in up to 5% of glioblastoma (GBM) and it remains unclear why such independent amplification event
296 V) and microcephaly has been established, it remains unclear why ZIKV, but not other pathogenic flavi
297 equent cause of death and disability, and it remains unclear why, of all body organs, the brain is mo
298 between folate status and insulin resistance remains unclear with very limited experimental support.
299  diseases, but its effect on lupus pathology remains unclear, with opposing trials in murine models o
300 cular mechanism of eukaryotic TCR initiation remains unclear, with several long-standing unanswered q

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