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1        In many settings, recent or prior injection drug use remains a barrier to accessing direct-acting antiviral treatm
2 cient reagent exchange on chip for large numbers of embryos remains a bottleneck.
3      Interreader variability in semantic feature annotation remains a challenge and affects the reproducibility of predic
4 in recent years, processing the resulting radiomic datasets remains a challenge due to the lack of specific tools for doi
5  microstructure, chemistry and function of energy materials remains a challenge for instrumentation science.
6   Disentangling the effects of m(6)A on viral and host RNAs remains a challenge for the field.
7                             Achieving long-range uniformity remains a challenge, but this process could provide a route t
8 ures that can lead to native folds or designable structures remains a challenge, since few existing metrics capture high-
9 edator-induced trait changes through particular communities remains a challenge.
10 ile bridging materials fabrication from nano- to macroscale remains a challenge.
11 ngful metric for risk stratification to guide interventions remains a challenge.
12   Despite impressive outcomes, relapse with CD19(-) disease remains a challenge.
13                 Cartilage repair in osteoarthritic patients remains a challenge.
14                           Drug delivery to the brain always remains a challenging issue for scientists due to the complex
15 east cancer have been extensively studied, while metastasis remains a challenging issue.
16                                               Preterm birth remains a common cause of neonatal mortality, with a dispropo
17                               Behind this application, SMCE remains a computational framework that supports the projectio
18                          While the commodification of water remains a contentious political issue, the valuation of this
19 e blue light cystoscopy improves diagnostic sensitivity, it remains a costly and invasive approach.
20                                       However, CPR duration remains a critical determinate of survival.
21      Appropriate selection and monitoring of anticoagulants remains a critical element of high-quality care for patients
22 regional variations in COVID-19, lung transplantation (LTx) remains a critical life-saving operation.
23                                       Although uncommon, HL remains a crucial test case for progress in cancer treatment.
24 n traditional supports (N-doped carbon, metal oxides, etc.) remains a formidable challenge, especially under high-tempera
25  linkage analyses and WGS to search for disease genes still remains a fruitful strategy for complex diseases with a varie
26 erstand and accurately predict such representative features remains a grand challenge.
27 ade-off between selectivity and sensitivity of such sensors remains a key challenge.
28 rogen (N) limits crop yield, and improvement of N nutrition remains a key goal for crop research; one approach to improve
29  lipid metabolism are known to be implicated in MNDs, there remains a lack of clarity regarding the key functional pathwa
30            Linking genomic variation to phenotypical traits remains a major challenge in evolutionary genetics.
31 ation antiandrogens, acquired resistance to hormone therapy remains a major challenge in treating advanced prostate cance
32 nal variants and key genes within these association regions remains a major challenge.
33                       While postoperative myocardial injury remains a major driver of morbidity and mortality, the abilit
34  accelerate MC simulation on GPUs whereas thread divergence remains a major issue for MC codes based on acceptance-reject
35                                                        This remains a particularly acute problem for triploids, which pro
36   Developing improved vaccines that elicit broader immunity remains a public health priority.
37                                                     Obesity remains a risk factor for CVD independent of major metabolic
38                                          Spinal cord injury remains a scientific and therapeutic challenge with great cos
39 npersistence) with respect to evidence from clinical trials remains a significant barrier to optimizing real-world outcom
40                                                   Actuation remains a significant challenge in soft robotics.
41 measurement of such distances for a conformational ensemble remains a significant challenge.
42 ism of this multi-redox reaction on metal-oxide photoanodes remains a significant experimental and theoretical challenge.
43 to acute ST-segment elevation myocardial infarction (STEMI) remains a significant global health problem.
44 en short range order and cation-oxygen-vacancy coordination remains a subject of active debate.
45                   Defining discontinuous antigenic epitopes remains a substantial challenge, as exemplified by the case o
46 on of metabolite abundance to sample input in heart tissues remains a technical challenge.
47 matin immunoprecipitation followed by sequencing (ChIP-seq) remains a tedious (>2 d), manually intensive, low-sensitivity
48                                      Pancreatic cancer (PC) remains a therapeutic challenge because of its intrinsic and
49 optimal strategy for this highly curable lymphoma, however, remains a topic of intense discussion and polarises opinion a
50                                      Root resection therapy remains a treatment solution for molars with furcation defect