ライフサイエンスコーパス: remodeling

1 n suggests a new role of SPARC during tissue remodeling.

2 nases that participate in actin cytoskeleton remodeling.

3 r respiratory tract infection-induced airway remodeling.

4 f function of these mutants in promoting NMJ remodeling.

5 anges in cardiac metabolism cause myocardial remodeling.

6 el function for drug-induced neuroepigenetic remodeling.

7 key mechanism in synapse and neural circuit remodeling.

8 nd its predictive value for left ventricular remodeling.

9 actic protein 1 (MCP1)-induced vascular wall remodeling.

10 tors involved in specific aspects of cardiac remodeling.

11 on is indicated to avoid adverse ventricular remodeling.

12 d IGC did not change such adverse epigenetic remodeling.

13 ely investigate normal and impaired cervical remodeling.

14 through increased inflammation and vascular remodeling.

15 E2 synthesis has been associated with airway remodeling.

16 erapeutic target for airway inflammation and remodeling.

17 ment and a paradigm for tissue formation and remodeling.

18 rks to prevent left ventricular (LV) adverse remodeling.

19 s involved in axon guidance and cytoskeletal remodeling.

20 m response that leads to deleterious cardiac remodeling.

21 vasoconstriction and subsequent blood vessel remodeling.

22 secondary to cardiomyocyte loss and cardiac remodeling.

23 ex differences in aortic valve fibrocalcific remodeling.

24 treatment should be initiated before cardiac remodeling.

25 ed phases of inflammation, regeneration, and remodeling.

26 t human parasite, possibly through metabolic remodeling.

27 oteins, including many involved in chromatin remodeling.

28 tained beneficial effect on left ventricular remodeling.

29 key genes involved in cardiac metabolism and remodeling.

30 h increased muscle adipogenesis and atrophic remodeling.

31 orticoid receptor (MR)-mediated pro-fibrotic remodeling.

32 g inflammation and poor extracellular matrix remodeling.

33 ted previously, is involved in vascular wall remodeling.

34 results in extensive cardiac transcriptional remodeling.

35 actility and a reduction in cardiac fibrotic remodeling.

36 riptional downregulation during late cardiac remodeling.

37 TNtv to be associated with eccentric cardiac remodeling.

38 er and are major contributors to adventitial remodeling.

39 he repair phase disturbed bone formation and remodeling.

40 r and function and to slow this pathological remodeling.

41 B and greatly enhance CSB-mediated chromatin remodeling.

42 neovascularization, and promoting myocardial remodeling.

43 I progression, concomitant with phospholipid remodeling.

44 alcium kinetics studies, and markers of bone remodeling.

45 n of PtdIns(4,5)P2 microdomains and membrane remodeling.

46 only for long bone growth, but also for bone remodeling.

47 d fatty acids, which is indicative of active remodeling.

48 tion to new conditions by delaying chromatin remodeling.

49 inflammation, proliferation, and resolution/remodeling.

50 ; P=0.009), and lower incidence of eccentric remodeling (12% versus 48%; P=0.03).

51 we studied CSB's DNA-binding and nucleosome-remodeling activities at the single molecule level in re

52 st-microbes interplay potentially determines remodeling activities in the transplanted lung, highligh

53 ing PW1(+) and their involvement in fibrotic remodeling after MI.

54 -specific Smad3 loss had accentuated adverse remodeling after reperfused infarction and exhibited an

55 ated with significant atrial and ventricular remodeling, along with systolic dysfunction and comparab

56 rogram for fibrosis and extracellular matrix remodeling, although deletion of Tgfbr1/2 uniquely alter

57 sociated with airway tissue inflammation and remodeling, although persistent airflow obstruction in t

58 F or death risk and in the degree of reverse remodeling among comorbidity groups.

59 talloproteinases (MMPs) contribute to tissue remodeling and acute inflammation not only by degrading

60 h the TCA cycle are essential for epigenetic remodeling and are transiently and partially localized t

61 endocytosis pathways and supports organelle remodeling and biogenesis.

62 c promiscuity, and the ease or difficulty of remodeling and building onto existing protein scaffolds,

63 of mucus is an important component of airway remodeling and contributes to the mucus plugs and airflo

64 ive cell invasion, demonstrating that matrix remodeling and creation of invasive micro-tracks are not

65 DNA and recruiting the associated nucleosome remodeling and deacetylase (NuRD) complex.

66 o dCas9 to recruit the endogenous nucleosome remodeling and deacetylase complex, were both successful

67 Here we show that the Mbd3/nucleosome remodeling and deacetylation (NuRD) chromatin remodeling

68 insult caused cofilin activation and F-actin remodeling and decreased microtubule dynamics in the AIS

69 e used to assess microglia-mediated neuronal remodeling and dendritic spine density in the medial PFC

70 The histological analysis showed that remodeling and destruction of the bronchiolar and alveol

71 Adverse LV remodeling and deteriorating LV ejection fraction occurr

72 erable syndrome to one that leads to chronic remodeling and dilated cardiomyopathy.

73 ws the role of the ECM in cardiac repair and remodeling and discusses matrix-based therapies that may

74 Z-ring, which coordinates peptidoglycan (PG) remodeling and envelope constriction.

75 aled an upregulation of extracellular matrix remodeling and focal adhesion processes in tumors with h

76 nisms underlying lymphatic vessel formation, remodeling and function in a human cell context.

77 from LVD and sham hearts did not improve LV remodeling and function, cardiac MSCs from LVD exacerbat

78 ction was associated with alterations in HDL remodeling and functionality.

79 /Sucrose Non-Fermentable (SWI/SNF) chromatin remodeling and global methylation patterns that may allo

80 r recruitment to SpAs in the early stages of remodeling and has identified potential key candidate fa

81 may shed light onto obesity-related cardiac remodeling and heart failure.

82 as a new therapeutic target for pathological remodeling and heart failure.

83 Nuclear localization and nucleosome remodeling and histone deacetylase (NuRD) complex bindin

84 modomain protein ZMYND8 and NuRD (nucleosome remodeling and histone deacetylation) complex in the DNA

85 's osteoimmunomodulatory effects on skeletal remodeling and homeostasis are unclear in the healthy ad

86 zed by airway inflammation, mucus secretion, remodeling and hyperresponsiveness (AHR).

87 ease in FM was associated with LV concentric remodeling and impairment of systolic and diastolic func

88 ease in FFM was associated with LV eccentric remodeling and improved systolic and diastolic functiona

89 thological cardiac structural and functional remodeling and improves left ventricular functional rese

90 a multifunctional IDP involved in chromatin remodeling and in the development and progression of pan

91 ciated with structural and functional atrial remodeling and increased incidence of extra-PV triggers.

92 vated GDF-15 correlates with lack of reverse remodeling and increased mortality after TAVR and improv

93 ell migration and extracellular matrix (ECM) remodeling and is thus an essential aspect of complex, m

94 Parameters of ventricular remodeling and modulation of cardio-renal sympathetic ax

95 ll as regulation of the growth, cytoskeleton remodeling and motility, invasion of PDAC cells-all coll

96 o ubiquitous proteins implicated in membrane remodeling and mutated in centronuclear myopathies (CNMs

97 lessens the magnitude of adverse myocardial remodeling and promotes angiogenesis.

98 y and mortality and different patterns of LV remodeling and recovery of LV function when compared wit

99 lammation that may eventually lead to tissue remodeling and respiratory disease.Cystic fibrosis is ca

100 recently been shown to be involved in lipid remodeling and scavenging during replication.

101 ibutions during Drosophila epithelial tissue remodeling and show that Rab35 is dynamically planar pol

102 inus after the osteotome technique underwent remodeling and shrinkage; however, the outcome of the pr

103 elements of these genes result in chromatin remodeling and transcription activation.

104 critical role of adult stem cells in tissue remodeling and unravel the complexity of stem cell fate

105 ypertensive effects, (2) attenuating cardiac remodeling, and (3) increasing angiogenesis and cell sur

106 ng immune cell airway infiltration, cellular remodeling, and alteration of asthmogenic gene expressio

107 or flow-dependent vasodilation, blood vessel remodeling, and atherosclerosis.

108 ted with the initial STEMI severity, adverse remodeling, and long-term health outcome.

109 recovery of LV function, greater adverse LV remodeling, and more device implantations.

110 Mical-mediated F-actin disassembly, cellular remodeling, and repulsive axon guidance.

111 n HF are primed to induce cardiac injury and remodeling, and retain this memory on adoptive transfer.

112 oteases have diverse roles in the formation, remodeling, and the destruction of extracellular matrix.

113 Airway remodeling (AR) is a prominent feature of asthma and oth

114 changes in ventricular architecture (cardiac remodeling) are key factors to limiting progression of t

115 signaling (PIK3R1, VAV1), RHOA/cytoskeleton remodeling (ARHGEF3), RNA splicing (U2AF1), T-cell recep

116 on and chromosomal breakage, suggesting fork remodeling as a global fork slowing and protection mecha

117 es, loss of proliferative control, chromatin remodeling as well as extensive morphological alteration

118 ion and arrythmia, SMOC2, involved in matrix remodeling, as well as enkephalin and RUNX3, potentially

119 e expression profiles, among which catabolic remodeling, associated with high expression of metallope

120 Favorable cardiac remodeling at 6 months included decreases in end-diastol

121 ty volumes at day 3, followed by ventricular remodeling at day 30, and recovery at day 60 (P < 0.05,

122 egulated by SOX10 and MITF and for chromatin remodeling at distal and proximal regulatory sites.

123 1 occupancy occurs coincident with chromatin remodeling at some of these loci.

124 Through a process called perilacunar remodeling, bone-embedded osteocytes dynamically resorb

125 more, NFLG patients experienced less reverse remodeling but the same symptomatic benefit.

126 process requires actomyosin-driven membrane remodeling, but not microtubules.

127 is associated with global pulmonary vascular remodeling, but the severity of PH correlates most stron

128 soform interactome reveals extensive network remodeling by alternative splicing.

129 ated with less likelihood of adverse cardiac remodeling by cardiac magnetic resonance.

130 ains in mediating HFD-induced adipose tissue remodeling by influencing multiple functions including a

131 umans, molecular imaging of inflammation and remodeling can potentially help early diagnosis and moni

132 essential actions for ESCRT-III in membrane remodeling, cargo selection, and cargo retention, which

133 t size, LV ejection fraction, and adverse LV remodeling, changes associated with decreased neutrophil

134 edominantly in genes that regulate chromatin remodeling, chromosome alignment, and stability.

135 role of the SWI/SNF ATP-dependent nucleosome-remodeling complex in the repair of a defined DNA DSB.

136 Here we show that the INO80 chromatin remodeling complex is required for oncogenic transcripti

137 Targeted inactivation of SWI/SNF nucleosome-remodeling complex members Smarca4 (Brg1) or Arid1a had

138 emodeling and deacetylation (NuRD) chromatin remodeling complex opposes this transcriptional pioneeri

139 genes encoding subunits of the BAF chromatin remodeling complex that exhibited Ras-mediated dependenc

140 cooperates with a tissue-specific chromatin remodeling complex to activate brown fat identity genes.

141 and recruits a tissue-specific BAF chromatin remodeling complex to brown fat gene enhancers, thereby

142 ncoded BRG1 subunit of the SWI/SNF chromatin remodeling complex, we employed in vitro models of melan

143 is Swi1, a subunit of the SWI/SNF chromatin-remodeling complex.

144 actor (NURF), a member of the ISWI chromatin-remodeling complex.

145 Among them, the ATP-dependent chromatin remodeling complexes control the chromatin architecture

146 witch for other PTMs, and connects chromatin remodeling complexes into gene transcription and gene ac

147 on factors that recruit activating chromatin remodeling complexes.

148 matory drugs or components of the nucleosome remodeling deacetylase (NuRD) complex, which associate w

149 trum overlaps with that of several chromatin-remodeling developmental disorders.

150 tions and their association with right heart remodeling differ between AF-TR and left-sided heart dis

151 namic organ that undergoes continuous tissue remodeling during adulthood.

152 he potential role of tissue degeneration and remodeling during anuran metamorphosis as a mechanism fo

153 ontributions of mechanical signals to airway remodeling during asthma are poorly understood.

154 al alterations indicative of areas of tissue remodeling during gestation.

155 tokines, including TNF, interferes with bone remodeling during inflammation through Ca(2+)-dependent

156 ing are widely used to profile transcriptome remodeling during myocardial ischemia.

157 MPC-dependent ECM remodeling during the first week of a growth stimulus is

158 the surrounding extracellular matrix (ECM), remodeling ECM fiber network structure by condensing, de

159 This remodeling effect is mediated by the ubiquitination and

160 analyses suggest that the zonal location of remodeling enzyme LPCAT2 plays a role in the change in s

161 Human ALC1 is an oncogene-encoded chromatin-remodeling enzyme required for DNA repair that possesses

162 Furthermore, the Fun30 remodeling enzyme, which has been implicated in DNA repa

163 decreased expression of extracellular matrix remodeling-enzyme coding genes and increased levels of s

164 ISWI-family nucleosome remodeling enzymes need the histone H4 N-terminal tail t

165 regulation is modulated in part by chromatin-remodeling enzymes that control gene accessibility by al

166 c subunit of the mammalian SWI/SNF chromatin-remodeling enzymes, is required for both myoblast prolif

167 e discuss the transcriptional and epigenomic remodeling events associated with cell fate transitions

168 e histone modification profile and chromatin-remodeling events leading to Sp7 gene expression.

169 of epithelial cells underlies diverse tissue-remodeling events, but the mechanisms that coordinate in

170 (BPTF) is the largest subunit of nucleosome remodeling factor (NURF), a member of the ISWI chromatin

171 Chromatin remodeling factor metastatic tumor protein 1 (MTA1), one

172 tentials in normal hearts and during cardiac remodeling following myocardial infarction (MI).

173 distinguish exercise-induced arrhythmogenic remodeling from ARVC and post-inflammatory cardiomyopath

174 increased expression of extracellular matrix remodeling genes, while single-cell RNA-seq analyses sho

175 P<0.0001), more concentric left ventricular remodeling, greater right ventricular dilatation (base,

176 g PVT1 might be effective in reducing airway remodeling in asthmatic patients.

177 hy, was the commonest pattern of ventricular remodeling in ATTR.

178 e that participates in ATP-dependent protein remodeling in both eukaryotes and prokaryotes.

179 Zbtb7b impaired cold-induced transcriptional remodeling in brown fat, rendering mice sensitive to col

180 this study was: 1) to compare LA structural remodeling in experimental MI swine models recapitulatin

181 e conclude that the pathogenesis of vascular remodeling in hypoxic PH involves an early compartment-i

182 le in CE-induced AHR and airway inflammation/remodeling in long term models of allergic airway inflam

183 ive deterioration in LV function and adverse remodeling in mice with large infarcts, and in ischemic

184 and time-lapse imaging to visualize cochlear remodeling in mouse.

185 nce of AF, partly related to electroanatomic remodeling in obese patients.

186 implicating changes in extracellular matrix remodeling in other, related optic nerve pathological st

187 nflammation by several mechanisms: chromatin remodeling in promoter regions of specific genes, blocka

188 lation has been linked to occlusive vascular remodeling in pulmonary arterial hypertension (PAH) that

189 lopment when the brain undergoes substantial remodeling in response to the environment.

190 it is a strong predictor of left ventricular remodeling in ST-segment-elevation myocardial infarction

191 pectroscopy non-invasively detected abnormal remodeling in the Cox-1 null mouse, and clearly demonstr

192 (MT) dynamics is a key event of cytoskeleton remodeling in the growth cone (GC) during axon outgrowth

193 MF represents pathological remodeling in the heart associated with cardiac dysfunct

194 Exercise promotes metabolic remodeling in the heart, which is associated with physio

195 pecific actions of Smad3 regulate repair and remodeling in the infarcted myocardium.

196 itro Mechanistically, TRPV4 modulated matrix remodeling in the lung via 2 distinct but dependent path

197 activated fibroblasts associated with tissue remodeling in various common diseases such as cancer, ar

198 RV end-systolic remodeling index (RVESRI) was defined by lateral length

199 e correlated with high-risk plaque features (remodeling index [r=0.53, P=0.003], plaque burden [r=0.5

200 omoting chronic lung inflammation and tissue remodeling induced by cigarette smoke and highlight anot

201 activation, we demonstrate that cytoskeleton remodeling, induced by okadaic acid, restores lymphocyte

202 l infarction (LAI); and 2) to analyze how LA remodeling influences ischemic MR development.

203 In this study, we show that K6a network remodeling is a host defense response that directly up-r

204 Post-MI cardiac remodeling is a multifaceted process that includes activ

205 Arrhythmogenesis from aberrant electrical remodeling is a primary cause of death among patients wi

206 lowing transplantation, appropriate vascular remodeling is crucial to ensure the survival and functio

207 This vascular remodeling is reversible, and hydrogen sulfide donors ar

208 Localized extracellular matrix (ECM) remodeling is thought to stabilize the cleavage furrow a

209 Perturbation of CL remodeling leads to the rare X-linked genetic disorder B

210 HCN remodeling likely occurs in human athletes, as well as i

211 idase-7, -9, and -12, diverged from anabolic remodeling linked to maximal thrombospondin and platelet

212 AAA+ proteases and remodeling machines couple hydrolysis of ATP to mechanic

213 ponent of the BM-was capable of inducing BTB remodeling, making the BTB leaky in studies in vivo Furt

214 While chromatin remodeling mediated by post-translational modification o

215 e, indicative of their role in producing and remodeling molecules in the extracellular matrix.

216 endogenous yeast DNA sequence and chromatin-remodeling network, as judged by a yeast-like nucleosome

217 dent leukocyte TEM and compensatory arterial remodeling obeying Glagov's phenomenon.

218 subtypes may mediate the extensive chromatin remodeling occurring during epigenetic reprogramming and

219 Activity-dependent synaptic remodeling occurs during early-use critical periods, whe

220 chloride dysregulation is important for the remodeling of aberrant glutamatergic neuronal circuits.

221 ermore, we found that tafazzin catalyzes the remodeling of cardiolipin by combinations of forward and

222 are mechano-chemical GTPases involved in the remodeling of cellular membranes.

223 tions and demonstrate that global structural remodeling of chromatin underpins heart failure.

224 podocytes demonstrated loss of filopodia and remodeling of cortical actin.

225 The E6AP-dependent remodeling of dendritic arborization results from retrac

226 tatus could uniquely regulate the continuous remodeling of ECM in the normal TM.

227 ., GnTI, GnTII, and GnTIV) involved in early remodeling of glycans in the mammalian glycosylation pat

228 irus replication is known to cause extensive remodeling of Golgi and endoplasmic reticulum membranes,

229 otogenic drug challenge, in conjunction with remodeling of local connectivity.

230 ther interdisciplinary impacts for catalytic remodeling of natural products, including contributions

231 epressant properties of ketamine, structural remodeling of prefrontal and hippocampal neurons has bee

232 ith LPR1/2 to regulate Pi deficiency-induced remodeling of root architecture by modulating Fe homeost

233 The remodeling of root architecture is a major developmental

234 to self-associate and initiate Rac-mediated remodeling of the actin cytoskeleton.

235 othesis that alterations in TJ structure and remodeling of the actomyosin cytoskeleton modify epithel

236 been shown to induce structural and electric remodeling of the atria.

237 rophages was associated with almost complete remodeling of the chromatin landscape, as well as altera

238 Our studies provide evidence that remodeling of the fibronectin matrix in injured or disea

239 ryo-EM reconstructions of yeast PICs suggest remodeling of the interface between 40S protein Rps5/uS7

240 contribute to such long-lived changes is the remodeling of the ionotropic AMPA-type glutamate recepto

241 Remodeling of the left ventricle (LV) in response to pre

242 a signaling cascade that provokes structural remodeling of the RMS through recruitment of MMP-2 by a

243 IUGR is associated with vascular remodeling of the stem villus arteries.

244 The remodeling of the stromal extracellular matrix (ECM) has

245 d that AML progression leads to differential remodeling of vasculature in central and endosteal bone

246 solution by increasing inflammatory vascular remodeling of venous thrombi in vivo, and the potential

247 n both Abeta(1-40) oligomers and EGCG during remodeling offer a foundation for understanding the mole

248 superior to MCT in changing left ventricular remodeling or aerobic capacity, and its feasibility rema

249 Arterial remodeling participates pivotally in many diseases inclu

250 and MLT families, which resemble mobile gene-remodeling platforms that supply promoters and first exo

251 derail the experience-driven neural circuit remodeling process important for executive control of re

252 Pathological cardiac hypertrophy, a dynamic remodeling process, is a major risk factor for heart fai

253 ABSTARCT: Electrical and structural remodeling processes are contributors to the self-perpet

254 To study this process, we simulated membrane remodeling processes in the presence and absence of memb

255 In summary, these remodeling processes tuned photosynthesis according to t

256 This remodeling produces a distinct gene signature and new vu

257 ilencing modulates the splicing of the actin-remodeling protein gelsolin, increasing gelsolin express

258 pression was CHD2, which encodes a chromatin remodeling protein mutated to cause human epilepsies.

259 roader role in biology, including organellar remodeling, protein and organelle quality control, preve

260 n in vivo function of CHD Type III chromatin remodeling proteins in this process, and reveal the deta

261 d a strong positive correlation between bone remodeling rates, mitotic activity, and osteotomy site h

262 riments show that poly(dA:dT) tracts perturb remodeling reactions if within one and a half helical tu

263 ined fibroblast proliferation, impaired scar remodeling, reduced fibroblast-derived collagen synthesi

264 budding yeast Saccharomyces cerevisiae, ECM remodeling refers to sequential formations of the primar

265 ting preterm birth (PTB)-associated cervical remodeling remain unclear.

266 n myocardial infarction (MI)-induced cardiac remodeling remains unclear.

267 rdiac ischemic injury induces a pathological remodeling response, which can ultimately lead to heart

268 Pulmonary vascular remodeling severity was associated with reductions in th

269 We find that acute and pathological tubular remodeling significantly affect TATS electrical conducti

270 on and allowing natural uninterrupted tissue remodeling suggests new therapeutic opportunities in the

271 The multi-subunit chromatin-remodeling SWI/SNF complex determines gene expression pr

272 terplay of p300-HDAC2-Sin3A in the chromatin remodeling system is involved in HIF-1alpha degradation

273 Patients with NFLG had less severe AS and LV remodeling than patients with normal-flow high-gradient.

274 he different steps of CSB-mediated chromatin remodeling that can be regulated by NAP1L1.

275 asticity in VTA GABA cells, and the synaptic remodeling that can occur after Delta(9)-tetrahydrocanna

276 ta argue that TBI elicits pathological spine remodeling that contributes to behavioral deficits by al

277 GF) is implicated in the peritoneal membrane remodeling that limits ultrafiltration in patients on pe

278 ways have been implicated in stretch-induced remodeling, the control structures by which signals from

279 agic flux can result in pathological cardiac remodeling, the physiological signaling pathways that fi

280 ges responsible for adverse left ventricular remodeling, the relationship between inflammation and pr

281 to counteract the effects of adverse cardiac remodeling, thereby improving survival and quality of li

282 ical regulator of extracellular matrix (ECM) remodeling through its availability and stepwise polymer

283 imals, heterochromatin undergoes large-scale remodeling to create a compartment with low chromatin de

284 eft ventricular assist device (LVAD)-induced remodeling to identify mechanisms impeding recovery.

285 expenditure, and fat depot-specific cellular remodeling toward lowered energy storage capacity and br

286 But how local remodeling tunes stress production and dissipation, and

287 Pase motor, which selectively activates ALC1 remodeling upon recruitment to sites of DNA damage.

288 d purification scheme followed by structural remodeling using commercially available and recombinantl

289 f2) in regulating myocardial necroptosis and remodeling using genetic mouse models.

290 Expansive vessel wall remodeling was more frequent and intense with the BVS th

291 ventricular dysfunction, pulmonary vascular remodeling was not more severe.

292 nflammation, hyperresponsiveness, and airway remodeling were analyzed in allergen-sensitized and airw

293 e gene program linked to CREM-induced atrial remodeling were identified in the expression of genes re

294 ulmonary hypertension and pulmonary vascular remodeling were not or only slightly affected by Cox4i2

295 ubset of Ras GTPase genes linked to membrane remodeling were upregulated in cells infected with the h

296 antitative analysis of sacculus architecture remodeling), which measures subcellular peptidoglycan dy

297 emergence are both accompanied by cell-wall remodeling, which involves the INFLORESCENCE DEFICIENT I

298 namic consequences and extent of ventricular remodeling, which is an important predictor of future ou

299 es matrix-based therapies that may attenuate remodeling while promoting repair and regeneration.

300 directed response strategies, linking neural remodeling with outcome-based decision making.