ライフサイエンスコーパス: render @2 resistant to

1 of GPX, lowers cellular H(2)O(2) levels, and renders NB4 cells resistant to 1 micromol/L As(2)O(3).

2 However, constitutive expression of ATFx renders cells resistant to 24p3-mediated apoptosis.

3 und), which does not express a DsrA protein, rendered this strain resistant to 50% NHS.

4 ibroblasts had minimal effect on growth, but rendered the cells resistant to a subsequent transformat

5 enon by which a sublethal injurious stimulus renders the brain resistant to a subsequent damaging isc

6 tructurally related monofluorinated products renders them resistant to a second fluorination.

7 Mcl-1 overexpression rendered ALL cells resistant to ABT-263 and ABT-199, wit

8 ned that loss of these core SWI-SNF subunits renders SW13 cells resistant to activation of the RB pat

9 Sole modification at this site rendered ASNase resistant to AEP cleavage and suggested

10 of slight differences in CD4BS recognition, renders HIV-1 resistant to all but the most accurately t

11 amma(1)34.5 deletion mutant is sufficient to render translation resistant to alpha interferon.

12 RagC variants increased raptor binding while rendering mTORC1 signaling resistant to amino acid depri

13 tor Z-Asp-2,6-dichlorobenzoyloxymethylketone rendered cells resistant to analogue-induced caspase-3 a

14 in cells with the D473H point mutation that rendered them resistant to another Smo inhibitor, GDC-04

15 e bacteria exhibit a biofilm-mode of growth, rendering P. aeruginosa resistant to antibiotics and pha

16 Pseudomonas aeruginosa forms biofilms, which render it more resistant to antimicrobial agents.

17 , Stat1 inhibits cell proliferation but also renders cells increasingly resistant to antiproliferativ

18 ulate Bcl(XL) expression, which may not only render B cells resistant to apoptosis but also alter the

19 ficiently induce production of cytokines and render mast cells resistant to apoptosis in an autocrine

20 ogated cell migration in response to HGF but rendered cells resistant to apoptosis by cisplatin.

21 DFF45 deficiency rendered fibroblasts resistant to apoptosis induced by t

22 that expression of Bcr - Abl in HL-60 cells rendered them extremely resistant to apoptosis induced b

23 ure to doxorubicin or gamma irradiation, but rendered transformed cells resistant to apoptosis.

24 Pretreatment with IL-6 renders beta cells resistant to apoptosis induced by pro

25 ated RSK mutant abrogates Bad activation and renders melanoma cells resistant to apoptosis induced by

26 rine infected macrophage cell lines but also renders them resistant to apoptosis induced by staurospo

27 effect on the proliferation of B cells, but renders them specifically resistant to apoptosis induced

28 inactivation of tumor suppressor PTEN, thus rendering the cells resistant to apoptotic signals.

29 wth factor signaling, or oncogene expression renders cancer cells resistant to apoptotic signals and

30 Moreover, knockdown of hNOA1 renders cells more resistant to apoptotic stimuli such a

31 Elevated expression of ML-IAP renders melanoma cells resistant to apoptotic stimuli an

32 three lysines (Lys-42, Lys-43, and Lys-135) renders FLNa resistant to ASB2alpha-mediated degradation

33 resulted in increased NF-kappaB activity and rendered ML1 cells resistant to ATO-induced apoptosis.

34 associated with resistant malaria parasites rendered the complex resistant to atovaquone, thereby pr

35 Expression of a triple-Glu zwint-1 mutant rendered cells resistant to AurB inhibition during prome

36 Deletion of Bim in hematopoietic cells rendered mice resistant to autoimmune encephalomyelitis

37 Deletion of rpoN rendered E. faecalis resistant to autolysis, which in tu

38 of this mutant EGFR construct in a cell line rendered it resistant to AZD9291.

39 Mutations of CRD-NRG1 and NRG3 that render them resistant to BACE cleavage, as well as BACE

40 How ever, some DNA lesions that render deoxyribose resistant to beta-elimination are rem

41 Mutations within viral proteins 2C and 3A render poliovirus resistant to BFA.

42 esidue close to the active site of human AGT renders it highly resistant to BG without substantially

43 Over-expression of miR393 renders plants more resistant to biotroph pathogens and

44 0-172 and selected for clones with mutations rendering Escherichia coli resistant to both the alkylat

45 thus undergoes a process of maturation that renders it relatively resistant to both basal and polyam

46 We demonstrate that CRAF overexpression renders melanoma cells resistant to BRAF-targeting agent

47 ndent function of cyclin D1 is sufficient to render mice resistant to breast cancer initiated by ErbB

48 ion of AP-3, and reduced expression of AGAP1 renders AP-3 resistant to brefeldin A.

49 We have genetically engineered EBV-CTLs to render them resistant to calcineurin (CN) inhibitor FK50

50 utant FAK with a point mutation (V744G) that renders FAK resistant to calpain proteolysis but retains

51 t paxillin with a point mutation (S95G) that renders it partially resistant to calpain proteolysis.

52 Tumour hypoxia renders cancer cells resistant to cancer therapy, result

53 15 to glycine and showing that this mutation rendered BLM resistant to caspase 3 cleavage.

54 vides an important signal for CD25- T cells, rendering them resistant to CD25+ -mediated regulation a

55 to its receptor programmed death-1 (CD279), renders tumor cells resistant to CD8(+) T cell- and FasL

56 Overexpression of Bcl-x(L) in these cells renders them resistant to CD95-mediated apoptosis.

57 proteins Grp78, Grp94, and calreticulin and rendered cells resistant to cell death caused by a subse

58 d that the induction of WAF1/Cip1 expression rendered glioma cells resistant to cell death induced by

59 esive proteins, to anchor PEG onto surfaces, rendering the surfaces resistant to cell attachment.

60 tigen expressed in the secretory compartment renders B cells resistant to central tolerance.

61 in highly conserved CTR1 residues that have rendered hamster cells resistant to CERV2 include a uniq

62 n of these complexes in Nherf2(-/-) mice may render them more resistant to CFTR-mediated secretory di

63 As various antiapoptotic mechanisms render GBM cells resistant to chemo- and radiotherapy, w

64 Hypoxia is a common phenomenon in HNSCC and renders cancers resistant to chemo- and radiotherapy.

65 ly contributes to tumor development but also renders cancer cells resistant to chemotherapeutic agent

66 ucing apoptosis, suggesting that miR-18b may render MCL cells resistant to chemotherapy by decelerati

67 allmark of rapidly progressing solid tumors, renders tumor cells resistant to chemotherapy and radiat

68 Notably, overexpression of IKKepsilon rendered cells resistant to cisplatin, whereas knockdown

69 cer cell lines, and genetic knockout of CTR1 renders cells resistant to cisplatin in vivo.

70 able to glycosylate the second Thr in IRTT, rendering the sequence resistant to cleavage by RgpB.

71 arkably, a point mutation of MAVS at Cys-508 renders MAVS resistant to cleavage by NS3/4A, thus maint

72 Mutagenesis of this site renders Stat5 resistant to cleavage.

73 ts in an intrinsic developmental defect that renders CD4(Stat3)(-/-) resistant to CNS inflammatory di

74 ire direct interactions with T or B cells to render animals resistant to colitis.

75 , containing eight genes and five microRNAs, renders susceptible mice resistant to colitis and reduce

76 ex beads into the central corneal epithelium renders Chinese hamsters resistant to corneal infection

77 richia coli-T. denticola shuttle vector that renders T. denticola resistant to coumermycin was constr

78 ng the amide side chain of Asn(726) with Gln renders Top1N726Qp resistant to CPT, suggesting that the

79 ll surface MHC class I (MHC-I) molecules and render infected cells resistant to CTL in general is lik

80 These characteristics render tumors resistant to current therapies and account

81 RNIP1, slows the rate of ubiquitin turnover, rendering yeast resistant to cycloheximide.

82 APK target sites, S75 and S123, are altered, renders cells resistant to cytokine withdrawal, restorin

83 Remarkably, overexpression of LNK rendered the cells resistant to death induced by either

84 y, PDCD4 deficiency in pancreatic beta cells renders them resistant to death, and PDCD4 deficiency in

85 nscriptional activation function in vivo and render the activator resistant to degradation by proteas

86 Mutation of Ser(384) to alanine also rendered cyclin E resistant to degradation by Fbw7, with

87 tary mutations such as ATM-deficiency, which render abnormal cells resistant to developmental clearan

88 e likely by stabilizing the Myc protein, and rendered cells resistant to dexamethasone, which was rev

89 at increased mitochondrial metabolism should render animals resistant to diabetes.

90 Mutation of Tyr951 to Phe renders the enzyme resistant to dideoxynucleotides and D

91 ve dramatically attenuated FGF/ERK activity, rendering them resistant to differentiation.

92 sely related small heat shock protein Hsp27, renders C2C12 myoblasts resistant to differentiation-ind

93 tion of the otherwise spherical micelles and renders them resistant to disassembly by serum proteins

94 nal rearrangement, independent of D2L2, that renders the heptamer resistant to dissociation by SDS.

95 quently, M2 expression inhibited DNA repair, rendered cells resistant to DNA damage-induced apoptosis

96 ne enhanced cellular DNA repair activity and rendered the cells resistant to DNA damage; while trunca

97 ich induced expression of P-glycoprotein and rendered cells resistant to doxorubicin.

98 Disruption of the LXCXE-binding cleft on pRB renders it resistant to E7 binding and inactivation.

99 lost via small insertions or deletions that render the transcripts resistant to early steps of miRNA

100 for establishment of spindle bipolarity and renders cells partially resistant to Eg5 inhibitors.

101 n of p53 using small interfering RNA (siRNA) rendered these cells resistant to EGCG-mediated apoptosi

102 reduces innate recognition of C. neoformans, rendering the yeast resistant to elimination by the inna

103 ansduction in C3H/HeJ and C57BL/10ScCr mice, rendering them resistant to endotoxin yet highly suscept

104 Moreover, deletion of TRPC6 renders mice resistant to endotoxin-induced barrier dysf

105 acrophage cytokine and chemokine release and renders mice resistant to endotoxin-mediated lethality.

106 Silencing of p38alpha MAPK with siRNA rendered T cells resistant to ESAT-6 inhibition of IFN-g

107 topoisomerase IIalpha protein levels and to render cells resistant to etoposide, a topoisomerase II-

108 Loss of CTR1 rendered cells resistant to even high concentrations of

109 ed previously that sublethal ischemia, which renders neurons transiently resistant to excitotoxic cel

110 mediated by the ubiquitin-proteasome system, rendering neurons resistant to excitotoxicity.

111 Exposure to nicotine also rendered rats resistant to extinction when amphetamine w

112 ated the expression of Fas in CD8+ cells and rendered them resistant to Fas ligand-induced apoptosis.

113 Furthermore, forced expression of FLIP renders cells resistant to Fas-mediated apoptosis.

114 upts proximal Fas signaling events, but also renders cells resistant to Fas-mediated apoptosis.

115 decreases surface Fas antigen expression and renders fibroblasts resistant to Fas mediated apoptosis.

116 n in the channel subunit CNGB1b in mice that rendered the channel resistant to fast desensitization b

117 pathogens such as Mycobacteria or Chlamydia rendering these organisms resistant to fosfomycin.

118 by mutating methionine 46 to leucine, which rendered GAPDH highly resistant to free radical-induced

119 t insight into genetic mechanisms capable of rendering islets strongly resistant to free radical-medi

120 t a farnesylation-independent mutant of Rheb renders these tumors resistant to FTI therapy.

121 A mutation in Arg(213) renders EC-SOD resistant to furin processing.

122 n by expressing alpha2,3-sialyltransferase 1 rendered LNCaP cells resistant to galectin-1, showing th

123 lar fragment of murine Notch-1 as capable of rendering thymomas resistant to glucocorticoid-induced a

124 Finally, H2O2 rendered endothelial cells resistant to growth factors a

125 mutant deficient in tyrosine phosphorylation renders endothelial cells resistant to H(2)O(2).

126 Genetic modification can render crops resistant to herbicides, providing them wit

127 of the Th1-type pattern, and such a response rendered recipients more resistant to HSV vaginal infect

128 Disruption of eEF1A-1 expression rendered these cells resistant to hydrogen peroxide- and

129 y silence miR-15 family members in vitro and render cardiomyocytes resistant to hypoxia-induced cardi

130 nvolved in resistance to IFN, as its absence renders IBV less resistant to IFN treatment.

131 n addition, Ba/F3 cells expressing mutations rendering them resistant to IM (e.g., E255K, M351T) or t

132 T315 residue in the bcr/abl activation loop renders cells highly resistant to imatinib and to second

133 evated defenses against free radical damage, rendering these mice resistant to immune-mediated pancre

134 tic reinnervation prevents these changes and renders hearts remarkably resistant to induced arrhythmi

135 SAg that also targets Vbeta8(+) T cells, and rendered mice resistant to infection.

136 the expense of ISGF3-mediated transcription, rendering cells less resistant to infection.

137 8 antibodies coimmobilized on magnetic beads renders the cells resistant to infection by M-tropic str

138 rom wild mosquito populations in Zambia that renders the mosquito resistant to infection with the hum

139 ng domain of PKR disrupted pTRS1 binding and rendered PKR resistant to inhibition by pTRS1.

140 ing of XO to bovine aortic endothelial cells rendered the enzyme resistant to inhibition by oxypurino

141 ces the transcriptional activity of FKHR and renders it resistant to inhibition by Akt.

142 ino acid RAF1 mutant (RAF1 Ser259Ala), which renders it resistant to inhibition by phosphorylation, i

143 g induced by Flt3L, increased mTOR1 activity renders pDCs more resistant to inhibition by rapamycin.

144 Addition of p34(SEI-1) to cyclin D1-CDK4 renders the complex resistant to inhibition by p16(INK4a

145 s with a point mutation in SCAP (Y298C) that renders the protein resistant to inhibition by 25-hydrox

146 specific numerical chromosome abnormalities, rendering them differentially resistant to injury.

147 Deficiency in IL-21R expression renders NOD mice resistant to insulitis, production of i

148 r concentrations of inorganic manganous ions render some cells resistant to ionizing radiation and pr

149 TLK1B overexpression in mammalian cells rendered them more resistant to ionizing radiation (IR).

150 urvival genes that, at high levels of Stat1, render the cells resistant to IR or other inducers of ce

151 cate that alterations in PCPH expression may render tumor cells resistant to IR, and perhaps other DN

152 e missegregation rates have been reduced are rendered markedly more resistant to IR, exhibiting dimin

153 Expression of either K1L or C7L, however, rendered vK1L(-)C7L(-) resistant to IRF1-induced antivir

154 In conclusion, prior transient UO renders the kidney resistant to ischemia.

155 anesthetics: (i) mutations in the ZZZ1 gene render cells resistant to isoflurane, and the ZZZ1 gene

156 iety of primary human epithelial cancers and renders cancer cells resistant to killing.

157 This renders the organism resistant to killing by complement

158 hesis in cells cultured in serum-free medium renders them resistant to killing by 25-hydroxycholester

159 er FGF2 transcription or Akt phosphorylation rendered BAECs resistant to L5.

160 ed cell lines, the cell cycle status of HSCs render them resistant to lentivirus-mediated transductio

161 urated fatty acids and bioactive lipids that render macrophages resistant to lipid-induced ER stress.

162 Similarly, the genetic deficiency of Puma rendered murine hepatocytes resistant to lipoapoptosis.

163 NF-kappaB ODN renders DCs resistant to lipopolysaccharide stimulation.

164 (2-2.5 fold) in Jurkat T cell transfectants renders them resistant to lower doses (1-10 ng/ml) of ra

165 cidification, and function, and that LAPTM4B renders tumor cells resistant to lysosome-mediated cell

166 Deficiency in this repair process renders cells resistant to many clinically active chemot

167 rmore, introduction of S301A,S319A mutations rendered Runx2 resistant to MAPK-dependent activation an

168 those tumors lacking mismatch repair, which renders them resistant to methylating agents.

169 aused increased levels of mA3 expression and rendered them resistant to MMTV infection.

170 already contain cells that harbor mutations rendering them resistant to most chemotherapeutic agents

171 Absence of Bax/Bak renders cells resistant to mPTP opening and necrosis, ef

172 -1) ring complex (TRiC)-dependent mechanism, rendering neurons more resistant to mtHtt-mediated cell

173 F31A/F34A could be used for gene therapy to render normal cells resistant to MTX but sensitive to TM

174 ce to cell death is a hallmark of cancer and renders transformed cells resistant to multiple apoptoti

175 pressing these constructs in sensitive cells rendered the cells resistant to mutacin IV.

176 The effector non-T cells also rendered T cells resistant to myeloid-derived suppressor

177 bumin and nab-paclitaxel in cancer cells and rendered them resistant to nab-paclitaxel-induced apopto

178 ansmembrane component (gp41) of envelope can render the virus resistant to neutralization by monoclon

179 lysis of viral escape mutations on m157 that render it resistant to NK killing reveals that it is lik

180 serine residue for the active site cysteine renders protease 3C resistant to NO inhibition.

181 t strains bearing a mutation in tubulin that renders it resistant to nocodazole.

182 ppresses Notch1-mediated signaling in vitro, rendering primary keratinocytes resistant to Notch1-medi

183 int mutations such as P140A (ED50, 5 microM) render AGT resistant to O6-benzylguanine (BG).

184 ntiviral state in ovarian and breast tumors, rendering them resistant to oncolytic virotherapy.

185 n the mouse model of bacteremia, probably by rendering the organisms resistant to opsonophagocytic ki

186 Glyco-Gag in the virion also rendered MLV resistant to other cytosolic sensors of vir

187 screened in fission yeast for mutations that rendered cells resistant to overexpressed chk1(+).

188 Endogenous hydrogen sulfide (H2S) renders bacteria highly resistant to oxidative stress, b

189 rasite binding are concealed by PEG coating, rendering these cells resistant to P falciparum invasion

190 This reduction in pRB renders cells resistant to p16(ink4a)-mediated G(1) arre

191 Mutant Bcl-xL that bound p53, but not PUMA, rendered cells resistant to p53-induced apoptosis irresp

192 We show that B1-KD rendered A549 cells resistant to paclitaxel (PTX), pheno

193 reduces binding to a PARP inhibitor, thereby rendering cancer cells resistant to PARP inhibition.

194 s into highly potent IFN-producing cells and rendered these cells resistant to pathogenic RNA viruses

195 skeletal muscle and that oxidative phenotype renders myofibers resistant to pathological insults indu

196 KT, stimulate cell growth and migration, and rendered cells more resistant to PDK1 and PI3K inhibitio

197 hthamide prevented ADP ribosylation of eEF2, rendered cells resistant to PE and DT, but does not affe

198 n mice, gene-targeted deletion of caspase-12 renders animals resistant to peritonitis and septic shoc

199 ells by group A Streptococcus (GAS) and also renders the bacterium resistant to phagocytosis.

200 Concordantly, mutation of these sites rendered p27 resistant to phosphorylation and locked it

201 A mutation of Thr-20 to Ala renders MEF2 resistant to PKA phosphorylation in vitro a

202 phospho-sites abolishes betaTrCP binding and renders USP37 resistant to Plk1 activity.

203 presence of the T315I BCR/ABL mutation that renders the kinase resistant to presently available inhi

204 a) PML acts in vivo as a tumor suppressor by rendering the cells resistant to proapoptotic and differ

205 on of mouse macrophages by Toxoplasma gondii renders the cells resistant to proinflammatory effects o

206 Mutations in the protease render the virus resistant to protease inhibitors (PIs).

207 and that hypoxia alone is not sufficient to render HIF1alpha resistant to proteasomal cleavage and d

208 The hyperacetylation renders H3.3 resistant to proteasomal degradation despit

209 Deletion of the SOCS box in CP-SOCS3 renders it more resistant to proteasomal degradation, ex

210 n of authentic rabbit muscle GAPDH with tNOX renders the GAPDH resistant to proteinase K digestion.

211 letion of 6 amino acids spanning proline 485 rendered MerTK resistant to proteolysis and suppression

212 n of KAP-1 and the AB box of the KRAB domain rendering it resistant to proteolysis.

213 We describe a strategy for rendering peptides resistant to proteolysis by formulati

214 LPS pretreatment also rendered germfree mice resistant to pulmonary K. pneumon

215 ion or mutation of apoptotic inhibitors that render these tumors resistant to radiation.

216 compromised pseudohyphal differentiation and rendered it resistant to rapamycin.

217 in, and the expression of recombinant merlin renders them partially resistant to rapamycin.

218 c flux, allows indefinite proliferation, and renders cells resistant to ras-induced arrest.

219 These findings demonstrate that BRG-1 loss renders cells resistant to RB-mediated cell cycle progre

220 rase at the metaphase-to-anaphase transition renders it resistant to re-inhibition by residual securi

221 The mutations render beta-catenin resistant to regulation by a complex

222 horter 3' untranslated regions (3'UTRs) that render them resistant to regulation by miR-206.

223 nce of higher concentrations of doxycycline) rendered cells more resistant to SB/FP-mediated lethalit

224 ry cytokines by ligands of TLR3 and TLR4 and rendered mice resistant to septic shock.

225 in Toso(-/-) mice compared with WT animals, rendering them resistant to septic shock induced by lipo

226 that sequence-specific DNA binding of pCREB renders the protein resistant to serine 133 dephosphoryl

227 ed attenuation of SMPD1 in human NSCLC cells rendered them resistant to serum starvation-induced apop

228 the conformational impact of mutations that render Abl resistant to small-molecule kinase inhibitors

229 d to JQ1 even when harboring genetic lesions rendering them resistant to Smoothened antagonists.

230 inducible c-Jun and NF-kappaB activities and rendered cells resistant to stress-induced apoptosis.

231 f Lkb1 function as an early neoplastic event renders cells resistant to subsequent oncogene-induced t

232 t fails to activate them in the process, and renders them resistant to subsequent activation by TLR l

233 traviolet radiation, whereas ppGpp induction renders them more resistant to such challenges.

234 of the alkyltransferase in many tumour cells renders them resistant to such drugs.

235 BP-binding site to an "exposed" location can render Ci resistant to Sufu-mediated inhibition in the n

236 ited by Akt, but mutation of all three sites rendered FKHR resistant to suppression.

237 a consensus Akt phosphorylation site in DAP3 renders it resistant to suppression by active Akt in cel

238 Thus, activation of T cells by IL-15 renders T cells resistant to suppression by TGFbeta1-pro

239 GF-beta receptor by tumor-specific CD8 cells renders them resistant to suppression and is associated

240 Correspondingly, lesioning this area rendered animals resistant to systemically delivered ane

241 sical and alternative NF-kappaB pathways and rendered knockdown cells resistant to Tax-IRS.

242 the gene expression profiles of Rb1 mutants, rendering them more resistant to temozolomide.

243 s with the protein biosynthesis machinery to render this process resistant to tetracycline by a mecha

244 Ski are transcriptional repressors that may render some cells resistant to TGF-beta via binding Smad

245 ion of Ski in a TGFbeta-responsive cell line renders it resistant to TGFbeta-induced growth inhibitio

246 fication present in the therapeutic mAb that renders it resistant to that enzyme.

247 receptors and IFN-gamma receptors appears to render cells highly resistant to the replication of HSV-

248 ively suggest that NS5A expression alone can render cells partially resistant to the effects of IFN a

249 neered symbiotic bacteria have been shown to render mosquitoes resistant to the parasite, the challen

250 to disrupt the GTPase activity of Ras and to render Ras resistant to the actions of GTPase activating

251 ave isolated genes that, when overexpressed, render Saccharomyces cerevisiae resistant to the volatil

252 r findings imply that STAT5CA expression can render TCs resistant to the immunosuppressive environmen

253 ns in the genes encoding the protein targets render the tumours resistant to the effects of the drugs

254 A mutation in the pmr5 gene rendered Arabidopsis resistant to the powdery mildew spe

255 hich tyrosine 66 is mutated to phenylalanine rendered cells partially resistant to the effects of Src

256 Increasing the amount of OSBP oligomer rendered cells resistant to the effects of cholesterol d

257 In contrast, p53 disruption rendered cells strikingly resistant to the effects of th

258 ment with these data, miR-155 overexpression rendered DLBCLs resistant to the growth-inhibitory effec

259 ER inhibitor or ERalpha-specific antagonist rendered hypoxic animals resistant to the beneficial eff

260 blation of the PKC phosphorylation site S144 rendered TRPV5 resistant to the action of plasmin.

261 In addition to rendering the plants resistant to the growth inhibitory

262 gle amino acid substitutions in cytochrome b rendering the yeast resistant to the inhibitor.

263 rine 37 (a target of GSK3beta) to an alanine renders beta-catenin resistant to the degradatory action

264 BRCT domains with a dimerization motif also renders cells resistant to the dominant negative effect

265 tivation by Smad3, and overexpression of Ski renders cells resistant to the growth-inhibitory effects

266 verexpression of the human A3 receptor cDNA, renders the myocytes resistant to the deleterious effect

267 ng DNA mismatch repair into these cell lines renders them resistant to the action of this drug.

268 stance and acts by sequestering antifungals, rendering cells resistant to their action.

269 elial-to-mesenchymal transition (EMT), which renders them resistant to therapies targeted to the prim

270 ed by GC-clamped punctuation sequences which render them resistant to thermal denaturation, allowing

271 a membrane in exchange with protons, thereby rendering cells resistant to these compounds.

272 eficiency of either mismatch repair activity renders cells highly resistant to this class of drug, bu

273 in-dependent kinase inhibitor (CKI), p27, to render cells resistant to TK/prodrug by inhibiting DNA s

274 the gap junction protein connexin 43 (Cx43) renders GBM cells resistant to TMZ through its carboxyl

275 vate the unfolded protein response (UPR) can render cells resistant to topoisomerase II poisons.

276 Strikingly, knockout of GPX1 rendered mice resistant to toxicities of drugs including

277 cytochrome c release by Bcl-2 overexpression rendered LNCaP cells resistant to TRAIL plus wortmannin

278 ectin-3 in J82 human bladder carcinoma cells rendered them resistant to TRAIL-induced apoptosis, wher

279 ion increases with increasing viral load and renders cells resistant to TRAIL-induced death.

280 AIL)-induced apoptosis, and knockdown of CAS renders cells resistant to TRAIL.

281 (G12V)-induced mitochondrial dysfunction and renders cells resistant to transformation.

282 ponse to abnormal mitogenic signals but also renders tumor cells resistant to treatment by cytotoxic

283 tor on conventional T cells during TSS could render them resistant to Treg-mediated suppression, cont

284 activated potassium channel SKCa3 into IKCa1 rendered the channel resistant to triarylmethanes.

285 the Cys342Thr mutant in a HEK293T cell line rendered it completely resistant to triptolide, thus val

286 of pdcd4 cDNA in stably transfected P+ cells rendered cells resistant to tumor promoter-induced trans

287 In addition, Six1 overexpression renders OCC resistant to tumor necrosis factor-related a

288 ts in functional deficiency of NF-kappaB and renders T cells resistant to tumor necrosis factor alpha

289 Phosphorylation renders Cdt1 resistant to ubiquitin-mediated degradation

290 rosylation of FLIP is an important mechanism rendering FLIP resistant to ubiquitination and proteasom

291 showed that activation of JNK or p38 kinase renders ATF2 resistant to ubiquitination and degradation

292 ) does not affect catalytic function, but it renders the enzyme resistant to ubiquitination and degra

293 he high-altitude variant of CDT1 (Ala537Val) renders cells more resistant to UV irradiation, and the

294 hanges within A3G in two AGM subspecies that render it resistant to Vif proteins, except for Vif from

295 abolic shift in macrophages is sufficient to render mice resistant to viral challenge, demonstrating

296 reatment or silencing Epac-1 gene expression rendered cells resistant to viral infection.

297 We conclude that retinoids render macrophages resistant to virus replication by mod

298 Fusion to the cytoplasmic protein muNS rendered the protein resistant to Vpx-mediated degradati

299 rmacologic inhibition, and genetic deletion) rendered mice more resistant to WNV lethality.

300 Importantly, inhibition of Dmp53 function renders cells resistant to X ray-induced apoptosis, sugg