ライフサイエンスコーパス: renoprotective

1 antiproteinuric and, therefore, likely to be renoprotective.

2 nhibit the angiotensin-converting enzyme are renoprotective.

3 tor of progression and that its reduction is renoprotective.

4 th diabetes, but it is unknown whether it is renoprotective.

5 II receptor blockers--have been shown to be renoprotective.

6 eneous nuclear ribonucleoprotein F (hnRNP F) renoprotective action in a type 2 diabetes (T2D) mouse m

7 exerted more effective anti-albuminuric and renoprotective action than eplerenone.

8 We have shown that vitamin D exerts renoprotective actions by transcriptionally suppressing

9 In patients with diabetes, additional renoprotective actions of these substances beyond loweri

10 ur previous studies have demonstrated potent renoprotective activity for 1,25-dihydroxyvitamin D (1,2

11 are a general class of steroids that possess renoprotective activity in glomeruli through their inter

12 p-regulation likely accounts for part of the renoprotective activity of vitamin D.

13 The lack of a truly 'renoprotective' agent has hampered our efforts in preven

14 he possibility of a relationship between its renoprotective and anti-inflammatory activity.

15 Mechanistically, the renoprotective and antiatherosclerotic effects of DMAG a

16 tory cells, WT CD4(+)CD25(+) cells were more renoprotective and localized to the kidney more efficien

17 d granulocytes seem to obscure the potential renoprotective and positive survival effects of pluripot

18 inediones have recently been suggested to be renoprotective, and to modulate podocyte glucocorticoid-

19 ession: treatment of hypertension and use of renoprotective, anti-hypertensive medication.

20 gy inhibition with 3MA markedly reversed the renoprotective, anti-inflammatory and anti-apoptotic eff

21 -induced nephrotoxicity remains unclear, and renoprotective approaches during cisplatin-based chemoth

22 Most human studies testing the renoprotective benefit of adding an angiotensin receptor

23 In conclusion, these data do not suggest a renoprotective benefit of sulodexide in patients with ty

24 strate that angiotensin blockade may provide renoprotective benefits, independent of its BP-lowering

25 ery, which associated with activation of the renoprotective beta-hydroxybutyrate signaling pathway.

26 uggest a mechanism for dynamic regulation of renoprotective BMP7 signaling in the S3 segment of the p

27 utophagosomes in postischemic kidneys may be renoprotective, but whether this accumulation results fr

28 Tamoxifen was renoprotective despite having no effect on the sustained

29 used as an intermediate end point to assess renoprotective drug efficacy.

30 y disease, but the mechanism underlying this renoprotective effect is unknown.

31 Based on the previous demonstration of a renoprotective effect of arginine-glycine-aspartic acid

32 An additional renoprotective effect of irbesartan, independent of achi

33 The renoprotective effect of preconditioned nanofibers assoc

34 meta-analysis to comprehensively assess the renoprotective effect of remote ischemic preconditioning

35 cantly lower in mutant rats, demonstrating a renoprotective effect of the mutation.

36 The lack of a statistically significant renoprotective effect of theophylline may result from in

37 The aim of this study is to investigate the renoprotective effect of xenon on early allograft injury

38 This renoprotective effect remained significant but attenuate

39 s indicate that natriuretic peptide exerts a renoprotective effect via inhibiting phosphorylation of

40 To address the renoprotective effect(s) of LPO inhibition, the efficacy

41 This renoprotective effect, although not complete, was seen w

42 inhibitors in Tg26 mice revealed an additive renoprotective effect, as suggested by reduction of prot

43 de, a GSK3beta activator, largely offset its renoprotective effect.

44 In conclusion, Cav2.2 inhibition exerts renoprotective effects against the progression of diabet

45 These renoprotective effects associated with inhibition of TGF

46 pheral stem cell numbers failed to exert any renoprotective effects but rather was associated both wi

47 ling, a natriuretic peptide receptor, exerts renoprotective effects by stimulating natriuresis and re

48 rse these modifications could have potential renoprotective effects for diabetic nephropathy.

49 torvastatin, atorvastatin seems to have more renoprotective effects for the studied chronic kidney di

50 phosphodiesterase type 5 (PDE5) might exert renoprotective effects in DN.

51 nthesis of 20-HETE with HET0016 reversed the renoprotective effects in SS.5(BN) rats.

52 ed in the kidney, and their agonists exhibit renoprotective effects in type 2 diabetes.

53 tabolic status and/or obesity, exerts direct renoprotective effects in vivo.

54 the first evidence that 2-OHE exerts direct renoprotective effects in vivo.

55 ype 2 diabetes, and canagliflozin may confer renoprotective effects independently of its glycemic eff

56 ls, but whether these actions translate into renoprotective effects is unknown.

57 The renoprotective effects of A717 are independent of any ch

58 The renoprotective effects of ACE inhibitors may result, in

59 n vivo by small interfering RNA reversed the renoprotective effects of AG.

60 Few studies have directly compared the renoprotective effects of angiotensin II-receptor blocke

61 We conclude that the renoprotective effects of enalapril, losartan, or combin

62 This study suggests novel renoprotective effects of ET-A blockers and supports fur

63 Thus, the renoprotective effects of LA in D were not attributable

64 We examined the renoprotective effects of Ly, a novel non-steroidal mine

65 The renoprotective effects of miR-29a in diabetes-induced lo

66 nt10a expression after ADR accompanied these renoprotective effects of paricalcitol.

67 Our findings confirm the renoprotective effects of puerarin in an experimental mo

68 inhibition of Nur77 expression mediated the renoprotective effects of retinoic acid.

69 factor-1alpha was critical in mediating the renoprotective effects of S1P(2)R inhibition.

70 nuria (Sun-MACRO) trial, which evaluated the renoprotective effects of sulodexide in patients with ty

71 uggests a potential link between HGF and the renoprotective effects of uPAR.

72 ggest that CCR2 inhibition with CCX140-B has renoprotective effects on top of current standard of car

73 These novel renoprotective effects suggest a role for simvastatin in

74 onic acid), EPC mobilization was blunted and renoprotective effects were absent.

75 These renoprotective effects were accompanied by reduced syste

76 These renoprotective effects were not observed with hydralazin

77 ctivated receptor-alpha (PPARalpha) displays renoprotective effects with an unclear mechanism.

78 This study was undertaken to evaluate the renoprotective effects, as well as the optimal timing an

79 (Val) as an angiotensin receptor blocker has renoprotective effects, but the molecular mechanisms res

80 Animal studies suggest that vitamin D has renoprotective effects.

81 in-II receptor blockers (ARBs) have specific renoprotective effects.

82 e from a 6-year clinical trial that assessed renoprotective efficacy of losartan.

83 The renoprotective efficacy of the vasopeptidase inhibitor o

84 ht be associated with differences in chronic renoprotective efficacy, additional rats were included i

85 evidence supporting its antiproteinuric and renoprotective efficacy.

86 lly, we induced or inhibited activity of the renoprotective enzyme heme oxygenase (HO) and determined

87 thermore, administration of this complex was renoprotective, evidenced by improved renal function, ma

88 identify renal tubular MIF as an endogenous renoprotective factor in progressive kidney diseases, ra

89 cyte influx and, more importantly, amplified renoprotective heme-oxygenase-1 protein and mRNA express

90 In this study, we compared the renoprotective, hemodynamic, and hematologic activities

91 Blockade of the renin-angiotensin system is renoprotective in a variety of chronic nephropathies, bu

92 In conclusion, PFD is renoprotective in diabetic kidney disease and may exert

93 modulating Fcgamma receptor signaling may be renoprotective in diabetic nephropathy.

94 (A(2A)R) activation was recently shown to be renoprotective in diabetic nephropathy.

95 Angiotensin receptor blockers are renoprotective in hypertensive azotemic patients with ty

96 In contrast, VEGF seems to be renoprotective in nondiabetic renal disease.

97 peptidase-4 (DPP-4), which cleaves GLP-1, is renoprotective in rodent ischemia-reperfusion injury mod

98 s, cardioprotective in rodents and pigs, and renoprotective in rodents.

99 The authors conclude that E(2) is renoprotective in the aging DSS rat by attenuating glome

100 lp further improve the cost-effectiveness of renoprotective interventions is a matter of investigatio

101 The bioflavonoids quercetin and curcumin are renoprotective natural antioxidants.

102 progressive kidney disease, underscoring its renoprotective potential.

103 al and clinical studies have established the renoprotective properties of renin-angiotensin-aldostero

104 during preconditioning was essential to the renoprotective properties of the nanofibers.

105 that the two classes of drugs share similar renoprotective properties.

106 agents with potential immunosuppressive and renoprotective properties.

107 these results suggest that adiponectin is a renoprotective protein after podocyte injury.

108 This association suggests a renoprotective rather than a tubulotoxic effect of NEFA.

109 ocytochemistry, lending further support to a renoprotective role for OPN.

110 hese data indicate that OPN plays a critical renoprotective role in vivo as an inhibitor of CaOx crys

111 We have shown that FXR and TGR5 have renoprotective roles in diabetes- and obesity-related ki

112 e lack of evidence of benefit of traditional renoprotective strategies, and newer techniques that may

113 nd clinical evidence for rIPC as a potential renoprotective strategy, and discusses the underlying me

114 N-acetylcysteine is more renoprotective than hydration alone.

115 ation might provide a therapeutic option for renoprotective therapy.

116 ed angiopoietin-1 therapy shows promise as a renoprotective tool in the early stages of diabetic kidn

117 During the 15 years of follow-up, the use of renoprotective treatment increased from 56 to 82%, and B

118 nclusion, despite the widespread adoption of renoprotective treatment, patients with type 1 diabetes

119 AKI induces the renoprotective upregulation of survivin expression in ki

120 nduced cell survival, and S1P1R agonists are renoprotective via direct effects on the tubule cells.