ライフサイエンスコーパス: repair enzyme

1 d reaction mechanism for this intriguing DNA repair enzyme.

2 B points to its candidacy as a tRNA splicing/repair enzyme.

3 ls that PE exemplifies a unique class of DNA repair enzyme.

4 function as a general 3'-end-processing DNA repair enzyme.

5 functions as a uracil DNA glycosylase (UDG) repair enzyme.

6 bition of poly(ADP-ribose) polymerase, a DNA repair enzyme.

7 NA, implicating it as a flavin-dependent DNA repair enzyme.

8 p2 are more toxic than in cells lacking this repair enzyme.

9 e exonuclease into a recombination-promoting repair enzyme.

10 erichia coli exonuclease III (ExoIII), a DNA repair enzyme.

11 TOP1-mediated protein-linked DNA break (PDB) repair enzyme.

12 e when the damaged base binds to its cognate repair enzyme.

13 ns in alkylated base recognition by this DNA repair enzyme.

14 ndonuclease 1 (Ape1), the major oxidized DNA repair enzyme.

15 vement of nucleotide excision repair or UVDE repair enzymes.

16 ble and not regulated by the availability of repair enzymes.

17 ATM activation and inhibiting DNA binding of repair enzymes.

18 a variety of proteins, including several DNA repair enzymes.

19 d association with DNA damage checkpoint and repair enzymes.

20 which may reduce DNA lesion accessibility to repair enzymes.

21 repair via interaction with a number of DNA repair enzymes.

22 repair of these adducts by the base excision repair enzymes.

23 ng after possible down-regulation of the DNA repair enzymes.

24 n and excision of damaged nucleobases by DNA repair enzymes.

25 ut the impact of higher order folding on DNA repair enzymes.

26 ich Chk2 protein regulates expression of DNA repair enzymes.

27 , and thereby prime it for processing by DNA repair enzymes.

28 gh the relation between nitric oxide and DNA repair enzymes.

29 significant reduction in levels of excision repair enzymes.

30 ducts by DNA transcription, replication, and repair enzymes.

31 found to be a target of nucleotide excision repair enzymes.

32 g intermediates may be a common theme in DNA repair enzymes.

33 es by proofreading exonucleases and mismatch repair enzymes.

34 bserved in the FPG DNA glycosylase family of repair enzymes.

35 h the lyase activity of type I base excision repair enzymes.

36 FTO), but only a subset functions as DNA/RNA repair enzymes.

37 helicases, polymerases, recombinases and DNA repair enzymes.

38 m photolyases, bacterial light-activated DNA repair enzymes.

39 en members of this class of replication fork-repair enzymes.

40 mapping of modified nucleobases with cognate repair enzymes.

41 at may serve as a recognition signal for DNA repair enzymes.

42 in the initial recognition of damaged DNA by repair enzymes.

43 to strains deficient in other base excision repair enzymes.

44 sting that they are removed by a "metabolite repair" enzyme.

45 demonstrate this method using the human DNA repair enzyme 3-methyladenine DNA glycosylase (AAG).

46 d identification of VPg unlinkase as the DNA repair enzyme, 5'-tyrosyl-DNA phosphodiesterase-2 (TDP2)

47 Unlike the homologous DNA repair enzyme 6-4 PHOTOLYASE, CRYs have extended carboxy

48 Furthermore, the base excision repair enzyme 7,8-dihydro-8-oxoguanine glycosylase (OGG1

49 markably dependent on a single base excision repair enzyme, 7,8-dihydro-8-oxoguanine-DNA glycosylase

50 (oxo8dG) levels and the activity of the DNA repair enzyme 8-oxoguanine DNA glycosylase (Ogg1) in rat

51 ast cancer by genetically modulating the DNA repair enzyme 8-oxoguanine DNA glycosylase (OGG1) in the

52 ermine (a) the activity of two base excision-repair enzymes, AAG, the major 3-methyladenine DNA glyco

53 Using histone demethylase JMJD1A and DNA repair enzyme ABH2 as examples, we show that this family

54 ptamer selection to a medically relevant DNA repair enzyme, ABH2.

55 echanism to coordinate the activities of DNA repair enzymes across the genome.

56 pair pathways for more defined lesions, NHEJ repair enzymes act iteratively, act in any order, and ca

57 sin protein nanopore was used to monitor DNA repair enzyme activity based on base-specific interactio

58 The Escherichia coli DNA repair enzyme AlkB is a 2-oxoglutarate (2OG)-dependent F

59 s express nine paralogs of the bacterial DNA repair enzyme AlkB, an iron/2-oxoglutarate-dependent dio

60 quantitative mechanistic scheme for the DNA repair enzyme AlkB.

61 d into a substrate (ZP1BG) for the human DNA repair enzyme alkylguaninetransferase (AGT or SNAP-Tag).

62 igated our hypothesis that the base excision repair enzyme alkylpurine-DNA-N-glycosylase (APNG), whic

63 The use of an inhibitor of a DNA repair enzyme alone to selectively kill a tumour, in the

64 rporation of HIF-1 and the bi-functional DNA repair enzyme and transcriptional coactivator, Ref-1/Ape

65 d light on the interplay between central DNA repair enzymes and an essential molecular chaperone.

66 Factor for DNA (DNA-SPF), using specific DNA repair enzymes and antibodies, and Sun Protection Factor

67 , alone and in complexes with a suite of DNA repair enzymes and antibodies, to directly quantify UVA

68 erized by mutations in numerous nucleic acid repair enzymes and elevated IFN levels.

69 insights into metal inhibition of other DNA repair enzymes and glycosylases.

70 le-strand break using purified base excision repair enzymes and human whole cell extracts.

71 The data suggests that IL-6 activates mtDNA repair enzymes and induces cell cycle arrest allowing ti

72 r repairing molecular damage by means of DNA-repair enzymes and protein-repair enzymes such as methyl

73 ent interactions of HIV-1 and HIV-2 with DNA repair enzymes and SAMHD1 imply that these viruses use d

74 e response involves the rapid recruitment of repair enzymes and the activation of signal transducers

75 ion endonucleases and many recombination and repair enzymes) and the HNH superfamily (found in an equ

76 proteins, by side reactions of base excision repair enzymes, and by cellular exposure to bifunctional

77 spanning DNA damage, molecular structures of repair enzymes, and clinical studies on inhibition of DN

78 vation-induced cytidine deaminase (AID), DNA repair enzymes, and post-class-switch expression of IgA

79 ected mismatch repair, four oxidative damage repair enzymes, and two proteases for eliminating damage

80 The follow-on base excision repair enzyme, AP endonuclease 1 (APE1), stimulates the

81 he abasic site in the recognition by the DNA repair enzyme Ape1 is discussed.

82 Besides its prominent role as a DNA repair enzyme, APE1 was separately identified as a prote

83 there were progressive increases in the DNA repair enzyme APEX1, the cell cycle control proteins cyc

84 xpression of the essential base excision DNA repair enzyme apurinic endonuclease 1 (Ape1) in response

85 evated levels of the essential base-excision repair enzyme apurinic/apyrimidinic endonuclease 1 (APE1

86 eraldehyde-3-phosphate dehydrogenase and DNA repair enzyme apurinic/apyrimidinic endonuclease I prote

87 owever, mice deficient for the base excision repair enzyme, apurinic/apyrimidinic endonuclease 2 (APE

88 dition to repairing mismatched DNA, mismatch repair enzymes are known in higher eukaryotes to directl

89 Two other DNA repair enzymes are known to repair epsilon-base lesions,

90 Host repair enzymes are predicted to complete this process.

91 Its effects on polymerases and repair enzymes are unknown.

92 ansposases, recombinases, integrases and DNA repair enzymes) are being harnessed or modified for the

93 The presence of a repair enzyme as a component of the viral replication ma

94 n of the DNA replication, recombination, and repair enzymes as well as the viral capsid and tail stru

95 e demonstrate that, when bound to DNA, these repair enzymes become redox-active; binding to DNA shift

96 the first thermodynamic characterization of repair enzyme binding to lesion-containing duplexes.

97 Biochemical analysis reveals a single repair enzyme-binding site on 9-1-1 that can be blocked

98 ridges between RNA polymerase, ribosome, and repair enzymes, blurring boundaries between separate inf

99 ange the levels or activity of base excision repair enzymes, but significantly reduced chromatin DNA

100 polymerases stalled at DNA lesions obstruct repair enzymes, but this situation is turned to the adva

101 lfur cluster in DinG and likely in other DNA repair enzymes by NO may contribute to NO-mediated genom

102 Our findings suggest that RNA repair enzymes can evolve their specificities to suit a

103 enotype, such that animals lacking all 3 DNA repair enzymes cannot survive even a single bout of chem

104 The activity of repair enzymes carries its own risk, however, because th

105 dividual archaeal PCNA subunits for selected repair enzyme 'clients', and provides insights into the

106 ded lesions affects their recognition by DNA repair enzymes, clustered damages are more difficult to

107 Surprisingly, deficiency in all 3 DNA repair enzymes confers a massively synergistic phenotype

108 An array of DNA-repair enzymes constitutes an essential part of the line

109 Endonuclease III (EndoIII), a base excision repair enzyme, cooperate at long-range using DNA charge

110 Cleavage assays with lesion-specific DNA repair enzymes coupled to ligation-mediated PCR showed p

111 otein TP53I3, transcription factor ATF3, DNA repair enzyme DDB2, and the beta-adrenergic receptor ADB

112 Nonetheless, polymerase and repair enzymes distinguish between various oxidized abas

113 The DNA base excision repair enzyme DNA polymerase (pol) beta is presented wit

114 structures of the R283K mutant of human DNA repair enzyme DNA polymerase beta (pol beta) differing i

115 crystal structure of the human base excision repair enzyme DNA polymerase beta (Pol beta) in complex

116 We identified two promising genes in the DNA repair enzyme DNA polymerase beta and in the neuroendocr

117 ated for inhibitory activity against the DNA repair enzyme DNA-dependent protein kinase (DNA-PK), wit

118 The DNA repair enzyme, DNA polymerase beta (Pol beta), is among

119 erozygous for the critical DNA base excision repair enzyme, DNA polymerase beta.

120 cells show elevated activation of a key DSB repair enzyme, DNA-dependent protein kinase catalytic su

121 Fe-S incorporation into MMS19-dependent DNA repair enzymes, DNA repair capacity, sensitivity to DNA-

122 ation plays an important role in controlling repair enzymes during the DNA damage response (DDR).

123 tional formamidopyrimidine glycosylase (Fpg) repair enzyme (E) that recognizes an 8-oxodG lesion with

124 leases (e.g., T7 gene 6 exonuclease) and DNA repair enzymes (e.g., uracil-DNA glycosylase).

125 ted and probed with the Escherichia coli DNA repair enzyme endonuclease IV (endo IV), which recognize

126 ed; these adducts are readily excised by DNA repair enzymes engaged in nucleotide excision repair.

127 intramolecular electron transfer in the DNA-repair enzyme, Escherichia coli photolyase, a protein cl

128 nding protein-interacting protein (CtIP) DNA repair enzyme, establishing a role for CtIP in regulatin

129 Our understanding of how repair enzymes excise modified bases without acting on u

130 a coli RecQ, a central DNA recombination and repair enzyme, exhibits differential processing of DNA s

131 n replication and for the essential role of "repair" enzyme ExoIII in demethylation leading to the re

132 h as temozolomide lose their efficacy if DNA repair enzyme expression is upregulated.

133 DNA replication and repair enzyme Flap Endonuclease 1 (FEN1) is vital for ge

134 isoaspartate O-methyltransferase activity, a repair enzyme for isoAsp residues in vivo, remains stabl

135 yrosyl-DNA phosphodiesterase 1 (TDP1), a key repair enzyme for trapped Top1cc, hydrolyzes the phospho

136 elong to a family of flavoproteins acting as repair enzymes for UV-B-induced DNA lesions (photolyases

137 DNA mismatch repair enzymes (for example, MSH2) maintain genomic inte

138 gonucleotide purity is assayed using the DNA repair enzyme formamidopyrimidine DNA glycosylase and by

139 and its normal counterpart, guanine, by the repair enzyme, formamidopyrimidine-DNA glycosylase (Fpg)

140 The Escherichia coli DNA repair enzymes Fpg and MutY are involved in the preventi

141 f DNA with histones in chromatin impedes DNA repair enzymes from accessing DNA lesions.

142 ine DNA Glycosylase (TDG) is a base excision repair enzyme functioning in DNA repair and epigenetic r

143 ated demethylation promoted by Base Excision Repair enzymes further modifies methylation of the repai

144 Several human DNA replication and repair enzymes have recently been shown to be acetylated

145 Targeting the DNA repair enzyme human 8-oxoguanine DNA glycosylase (hOGG1)

146 ssion vector containing the gene for the DNA repair enzyme human 8-oxoguanine DNA glycosylase/apurini

147 The DNA repair enzyme human uracil DNA glycosylase (UNG) scans s

148 therapeutics as inhibitors of a critical DNA repair enzyme, human AP endonuclease.

149 rase lambda (pol lambda), a low-fidelity DNA repair enzyme in the X-family that fills short nucleotid

150 The presence of multiple versions of DNA repair enzymes in a single organism is usually thought t

151 importance of RecA and DNA recombination and repair enzymes in conferring resistance to H(2)O(2) dama

152 looping in CSR, and the roles of certain DNA-repair enzymes in CSR.

153 track that allows long-range sliding of DNA repair enzymes in their search for rare damage sites in

154 Analysis of the involvement of DNA repair enzymes in trimethoprim-induced cytotoxicity clea

155 n of DNA repair pathways and the function of repair enzymes in vivo have remained unclear because of

156 yrosyl-DNA-phosphodiesterase 1 (TDP1), a DNA repair enzyme, in ATL cells.

157 nine sulfoxide reductase (Msr), a methionine repair enzyme, in H. pylori stress resistance was evalua

158 adaptive processing of the DNA damage by DNA repair enzymes, in particular by MutM and MutY DNA glyco

159 ons are further processed by downstream DNA "repair" enzymes including error-prone translesion polyme

160 Because many DNA methyltransferases and DNA repair enzymes induce similar DNA distortions, these res

161 Therefore, targeting DNA repair enzymes into beta-cell mitochondria could be a po

162 purinic/apyrimidinic endonuclease 1 is a DNA repair enzyme involved in genome stability and expressio

163 ve characterized meningococcal base excision repair enzymes involved in the recognition and removal o

164 DNA 'sliding' by human repair enzymes is considered to be important for DNA dam

165 The promiscuity of DNA repair enzymes is particularly important, because it ena

166 A hallmark of these and other DNA repair enzymes is their use of base flipping to sequeste

167 oly(ADP-ribose) polymerase-1 (PARP-1), a DNA repair enzyme, is involved in the induction of necrosis

168 stream activities of the major base excision repair enzymes, it may act as a regulator for the base e

169 phoesterase (PE) domain of the bacterial DNA repair enzyme LigD possesses distinctive manganese-depen

170 We also found evidence that a DNA repair enzyme may play a role in modifying the sequence

171 Thus, induction of DNA repair enzymes may be a unique strategy for neuroprotect

172 their processing by cellular replication and repair enzymes may be differentially affected by their a

173 illing by HOCl, whereas over-expression of a repair enzyme, methionine sulfoxide reductase A, rendere

174 moprotection mediated by a mutant of the DNA-repair enzyme methylguanine methyltransferase could circ

175 Mutant forms of the DNA repair-enzyme methylguanine methyltransferase in particu

176 The mismatch repair enzymes MSH2, MSH3, and MSH6, implicated in repea

177 structurally elucidated a base-excision DNA repair enzyme, MutM, at the stage of initial encounter w

178 t overexpression of catalase or DNA mismatch repair enzyme, MutS, and antioxidant pretreatment limit

179 rol of the N-glycosylase reaction by the DNA repair enzyme, MutY, entails the organization of solvent

180 ds to oxidation of a DNA-bound base excision repair enzyme, MutY.

181 chondrial topoisomerase TOP1MT, the mismatch repair enzyme MUTYH, and the apurinic-apyrimidinic endon

182 ation in the gene encoding the base excision repair enzyme Nei endonuclease VIII-like 3 (NEIL3) that

183 Editing of the pre-mRNA for the DNA repair enzyme NEIL1 causes a lysine to arginine change i

184 The DNA repair enzyme NEIL1 is a DNA glycosylase that is involve

185 d using a lentiviral vector encoding the DNA repair enzyme O(6)-alkylguanine DNA alkyltransferase (AG

186 Expression of the DNA repair enzyme O(6)-methylguanine-DNA methyltransferase (

187 olomide; however, gliomas expressing the DNA repair enzyme O(6)-methylguanine-DNA methyltransferase (

188 ce gene, such as the P140K mutant of the DNA repair enzyme O6-methylguanine-DNA methyltransferase (MG

189 The DNA repair enzyme O6-methylguanine-DNA methyltransferase (MG

190 oduct 8-oxoG and increased levels of the DNA repair enzyme OGG-1.

191 the injury by increased production of mtDNA repair enzymes (OGG-1, Neil 1) and check point (p21, p53

192 r studying the activity of Klenow exo(-) and repair enzymes on templates containing the lesion.

193 racil DNA glycosylase (UNG2), a cellular DNA repair enzyme, on the virus mutation rate and on replica

194 es over DNA, the ionic dependence of the DNA repair enzyme PARP1 in DNA binding, and the interaction

195 The DNA repair enzyme photolyase provides a natural system that

196 quence identity with the light-activated DNA repair enzyme photolyase.

197 The same is also true for the DNA repair enzyme, photolyase.

198 ial cells, which, in turn, activates the DNA repair enzyme poly(ADP)-ribose polymerase.

199 Inhibition of the DNA repair enzyme poly(ADP-ribose) polymerase 1 (PARP1) with

200 ivation of caspase-3 and the cleavage of DNA repair enzyme poly(ADP-ribose) polymerase were inhibited

201 Inhibition of the DNA repair enzyme poly(ADP-ribose) polymerase-1 (PARP-1) has

202 dels, possibly through inhibition of the DNA repair enzyme poly-ADP-ribose polymerase and prevention

203 tol also resulted in cleavage of the nuclear repair enzyme, poly(ADP-ribose) polymerase (PARP) and in

204 nexin V binding, the inactivation of the DNA repair enzyme, poly(ADP-ribose) polymerase, and the acti

205 This may be due to the activation of the DNA repair enzyme, poly(ADP-ribose) polymerase, in response

206 /-) mice with targeted disruption of the DNA repair enzyme, poly(ADP-ribose) polymerase.

207 itinating activity regulate the cellular DNA repair enzyme polymerase eta and recruit it to potential

208 The dual function mammalian DNA repair enzyme, polynucleotide kinase (PNK), facilitates

209 se (AID) and is completed by error-prone DNA repair enzyme processing of AID-generated uracils.

210 Plant andphage tRNA repair enzymes protect yeast from gamma-toxin because th

211 t that Cry1 and Cry2, which evolved from DNA repair enzymes, protect genomic integrity via coordinate

212 f isoAsp in cells is limited by a ubiquitous repair enzyme, protein l-isoaspartyl methyltransferase (

213 two nonmembrane-bound ABC proteins, the DNA repair enzyme Rad50 and a structural maintenance of chro

214 marker of double-strand breaks) and the DNA-repair enzyme RAD51.

215 ed by the impaired recruitment of a core DNA repair enzyme, RAD51, to replication-induced DNA damage

216 strikingly reminiscent of one subset of DNA-repair enzymes, raising important mechanistic and drug-d

217 pacts are discussed in terms of differential repair enzyme recognition, processing and translesion sy

218 DNA repair enzymes recognize and remove damaged bases that a

219 The process by which DNA repair enzymes recognize and selectively excise damaged

220 The co-transcription factor and DNA repair enzyme, Redox effector factor-1/apurinic/apyrimid

221 g DNA-mediated electron transfer among these repair enzymes; redox activation upon DNA binding and ch

222 ion and the role of host double-strand break repair enzymes remain unknown.

223 studies Tomas Lindahl has shown how specific repair enzymes remove and replace damaged parts of DNA i

224 helicase is one of several recombination or repair enzymes required for efficient levels of pilin Av

225 tion enzymes, restriction endonucleases, DNA-repair enzymes, resolvases, intron splicing factors and

226 sferase, thioredoxin, glutaredoxins, and DNA repair enzymes responded most strongly to cadmium and ch

227 -methylcytosine, and follow-on base excision repair enzymes restore a G.C pair.

228 ng-standing questions about the way in which repair enzymes search for DNA lesions and form protein c

229 r109c and human FGGY could act as metabolite repair enzymes, serving to re-phosphorylate free d-ribul

230 covalent DNA-protein cross-links (DPCs) with repair enzymes such as DNA polymerase beta (polbeta).

231 DNA repair enzymes such as human uracil-DNA glycosylase (hUN

232 e by means of DNA-repair enzymes and protein-repair enzymes such as methyltransferase is found to be

233 acid phosphatases, 5'-nucleotidase, and DNA repair enzymes such as Mre11.

234 -oxidized abasic site with Klenow exo(-) and repair enzymes suggest that the lesion will be mutagenic

235 eveals a previously unsuspected role for the repair enzyme TDG as a repressor of smooth muscle differ

236 hylated cytosines requires the base excision repair enzyme TDG, but the mechanism by which TDG-depend

237 nteracts with and requires the base excision repair enzymes TDG and APE1 for active demethylation.

238 The DNA repair enzyme telomerase maintains chromosome stability

239 osyl-DNA phosphodiesterase 1 (Tdp1) is a DNA repair enzyme that acts upon protein-DNA covalent comple

240 cosylase) is one such silenced base excision repair enzyme that can restore DNA integrity.

241 nd a DNA 3' phosphate and functions as a DNA repair enzyme that cleaves stalled topoisomerase I-DNA c

242 ethyltransferase (MGMT), which encodes a DNA-repair enzyme that confers resistance to the combination

243 thyladenine DNA glycosylase I (TAG) is a DNA repair enzyme that excises 3-methyladenine in DNA and is

244 acil DNA glycosylase (UNG) is a powerful DNA repair enzyme that has been shown to stabilize a glycosy

245 cil DNA glycosylase (UNG2) is a cellular DNA repair enzyme that is essential for a number of diverse

246 oss-complementation group 1 (ERCC1) is a DNA repair enzyme that is frequently defective in non-small

247 ive site complex with DNA polymerase beta, a repair enzyme that plays an important role in base excis

248 uanine-DNA methyltransferase (MGMT) is a DNA repair enzyme that protects cells from carcinogenic effe

249 il DNA glycosylase (UNG) is an important DNA repair enzyme that recognizes and excises uracil bases i

250 recognition by Escherichia coli AlkB, a DNA repair enzyme that removes methyl adducts and some large

251 yrosyl-DNA phosphodiesterase (TDP1) is a DNA repair enzyme that removes peptide fragments linked thro

252 alkyltransferase (AGT) is a single-cycle DNA repair enzyme that removes pro-mutagenic O(6)-alkylguani

253 Ribonuclease H2 (RNase H2) is a nucleic acid repair enzyme that removes unwanted ribonucleotides from

254 e kinetic and thermodynamic parameters for a repair enzyme that targets nucleic acid substrates conta

255 ignificantly to the specificity of other DNA repair enzymes that bind to extrahelical bases.

256 Contrary to many DNA repair enzymes that can directly reject non-target sites

257 Archeoglobus fulgidus, are all base excision repair enzymes that contain the [4Fe-4S](2+) cofactor.

258 onserved substrate recognition domain in DNA repair enzymes that couples ATP-hydrolysis to remodeling

259 The Rh-PPO mechanism is reminiscent of DNA repair enzymes that displace mismatched bases, and is di

260 for the ubiquitous [4Fe-4S] clusters in DNA repair enzymes that involves redox chemistry and provide

261 ise a ubiquitous superfamily of nucleic acid repair enzymes that join 3'-OH and 5'-PO4 DNA or RNA end

262 minated purine nucleobases are essential DNA repair enzymes that protect the genome, and at the same

263 t recognize nucleobases, including other DNA repair enzymes that recognize other types of extrahelica

264 is a class of ubiquitous direct reversal DNA repair enzymes that remove alkyl adducts from nucleobase

265 ate that the method, in conjunction with DNA repair enzymes that remove damaged bases to produce alde

266 by DNA polymerases work in parallel with DNA repair enzymes that remove lesions produced by modified

267 NA editing ligases exemplify a family of RNA repair enzymes that seal 3'OH/5'PO(4) nicks in duplex RN

268 ns with other DNA methyltransferases and DNA repair enzymes that stabilize extrahelical nucleotides r

269 .TTC repeat during transcription attract DNA repair enzymes that then facilitate the expansion proces

270 ssed by uracil base excision and/or mismatch repair enzymes that ultimately generate switch region DN

271 ERASE (PIMT) is a widely distributed protein-repairing enzyme that catalyzes the conversion of abnorm

272 required for stabilization of base excision repair enzymes, the failure of cells to downregulate Mul

273 apparent lack of the normal set of mismatch repair enzymes, the results from this study may suggest

274 and its derivatives in DNA are bound by DNA repair enzymes through hydrogen bonding and pi-pi stacki

275 FAN1 encodes a DNA repair enzyme, thus implicating abnormalities in DNA rep

276 Human (h) DNA repair enzyme thymine DNA glycosylase (hTDG) is a key DN

277 have shown previously that the base excision repair enzyme thymine DNA glycosylase (TDG) acts as a po

278 nockout or catalytic inactivation of the DNA repair enzyme thymine DNA glycosylase (TDG) leads to emb

279 hOGG1-Tat fusion protein to target the hOGG1 repair enzyme to mitochondria and enhance mtDNA repair.

280 trategies for modulating the levels of mtDNA repair enzymes to delay or stall metastatic progression.

281 ktracking and recruiting nucleotide excision repair enzymes to exposed lesions.

282 RNA polymerase, allowing nucleotide excision repair enzymes to gain access to sites of damage.

283 containing the lesion to a form that allows repair enzymes to remove the blocking lesion and DNA syn

284 tin requires mechanisms that allow access of repair enzymes to the lesions.

285 The DNA repair enzyme uracil DNA glycosylase (UDG) utilizes base

286 A classic example is the DNA repair enzyme uracil DNA glycosylase (UDG) which recogni

287 reported Vpr interactions with base excision repair enzyme uracil DNA glycosylase (UNG2) and crossove

288 oretical study showed that the base excision repair enzyme uracil-DNA glycosylase (UDG) exploits elec

289 in are for T4 polynucleotide kinase, the DNA repair enzymes uracil-DNA glycosylase (UDG) and formamid

290 21 years ago, the DNA Repair Enzyme was declared "Molecule of the Year".

291 of the two mammalian uracil-DNA glycosylase repair enzymes, we were able to test this model of FU cy

292 nt for binding to the uracil DNA glycosylase repair enzyme were observed to influence HIV-1 virus mut

293 lfoxide reductase A (MsrA) is an antioxidant repair enzyme which reduces oxidized methionine to methi

294 DNA-dependent PK (DNA-PK) is a DNA repair enzyme, which we previously found played an impor

295 s, mitochondrial proteins, histones, and DNA repair enzymes, which have not been associated with diff

296 ents is limited because of the action of DNA repair enzymes, which mitigate the damage induced by the

297 Thus, RtcB is a bona fide RNA repair enzyme with broad physiological actions.

298 el to show that there is an optimum level of repair enzymes within cells which optimises the cell's r

299 an increased nuclear localization of the DNA repair enzyme XPA.

300 hanges in gene expression for cytokines, DNA repair enzymes, zinc transporters, signaling molecules,