ライフサイエンスコーパス: repair of

1 not essential for TDG-mediated excision and repair of 5-carboxylcytosine bases.

2 demethylation and selective recognition and repair of 5-carboxylcytosine.

3 rmediates occurring during the photo-induced repair of (6-4) photolesions by photolyases to specific

4 In humans, short-patch base excision repair of 8-oxoG:dA base pairs requires human DNA polyme

5 his was - a 4-month-old girl 32 days after a repair of a congenital diaphragmatic hernia, with ultras

6 pendent nucleosome-remodeling complex in the repair of a defined DNA DSB.

7 es affect the hetDNA profile associated with repair of a defined double-strand break (DSB) by the syn

8 ding a sgRNA and a repair template to induce repair of a disease gene in adult animals.

9 Restoration of pathogenicity by repair of a frameshift mutation in GPCMV gene GP129 usin

10 h commercial mesh (both lightweight) for the repair of a groin hernia in adult men in eastern Uganda

11 The most effective method for repair of a groin hernia involves the use of a synthetic

12 y, mNT has been implicated in cytosolic Fe-S repair of a key regulator of cellular iron homeostasis.

13 e dye promotes relatively rapid and complete repair of a Li(+) GB hydrogel destroyed by shearing.

14 The repair of a point mutation can be facilitated by combine

15 2AX "knockdown" cells did not generate GCRs, repair of a single engineered DNA DSB in fibroblasts tha

16 netic alterations arise through the aberrant repair of a single-stranded DNA gap, in a process that i

17 novel gap formation step is employed during repair of a variety of DNA lesions, including oxidative

18 nine DNA glycosylase is able to initiate the repair of A:oxoG by selectively cleaving the A base from

19 led 881 patients undergoing planned elective repair of AAA who were candidates for open and endovascu

20 iffer between elective open and endovascular repair of AAA.

21 utcomes after elective open and endovascular repair of abdominal aortic aneurysm (AAA), cost may be a

22 We found a lower rate of repair of abdominal aortic aneurysms and a larger mean a

23 Thresholds for repair of abdominal aortic aneurysms vary considerably a

24 ovascular sealing is a new technique for the repair of abdominal aortic aneurysms.

25 fficacy of biological mesh materials for the repair of abdominal wall hernia.

26 tic mesh is frequently used to reinforce the repair of abdominal wall incisional hernias.

27 a product of the human pcmt1 gene, catalyzes repair of abnormal l-isoaspartyl linkages in age-damaged

28 t-rich plasma (PRP) is used to stimulate the repair of acute and chronic cartilage damage even though

29 uplications might arise due to the concerted repair of adjacent single-strand breaks (SSBs).

30 only late during development in plants, the repair of adjacent SSBs indeed seems to have an importan

31 The shaping of a multicellular body and repair of adult tissues require fine--tuning of cell adh

32 AG), the enzyme that initiates base excision repair of alkylated bases, the flipped-out nucleotide is

33 for nucleotide and amino acid biosynthesis, repair of alkylated DNA and the synthesis of mechanosens

34 ATM was required for the efficient repair of all non-compatible ends including those repair

35 ive splicing defects that were restored upon repair of an ESRP1 mutant allele.

36 By monitoring repair of an induced DSB, we show that SiRTAs on chromos

37 s from the autograft directly contributed to repair of an osteonecrotic lesion, but this contribution

38 Compared with non-mesh repair, mesh repair of anterior compartment prolapse was associated w

39 All-cause mortality in patients after repair of aortic aneurysms of the descending thoracic ao

40 equire acetylation of APE1 for the efficient repair of AP sites and base damage in the genome.

41 ay contribute to the discovery and efficient repair of base damage in chromatin.

42 ls, we found that cAMP signaling accelerates repair of bi- and mono-functional platinum-induced DNA d

43 goal was to determine the optimal timing for repair of bile duct injuries sustained during cholecyste

44 Adequate sepsis control and delayed repair of biliary injuries should be considered for pati

45 ificity, low cost, and self-replication and -repair of biocatalysts.

46 ly new techniques to guide or accelerate the repair of bone.

47 is a homologous recombination, in which the repair of breaks in double-stranded DNA molecules is tak

48 Inaccurate repair of broken chromosomes generates structural varian

49 es ATM, ATR, and DNA-PKcs, which control the repair of broken DNA strands and relay the damage signal

50 unction with BLM or WRN and thus promote the repair of broken DNA.

51 may represent an improvement in the surgical repair of canalicular lacerations.

52 nks chondrocyte BMAL1 to the maintenance and repair of cartilage and suggest that circadian rhythm di

53 Anatomic repair of ccTGA effectively resolves the problem of fail

54 highly conserved enzyme focused on the self-repair of cellular DNA damage.

55 ase superfamily that we show accelerates the repair of chromosomal DNA single-strand breaks in avian

56 nd joining (TMEJ) has been implicated in the repair of chromosome breaks, but its cellular mechanism

57 the safety and feasibility of transcatheter repair of chronic severe TR with the MitraClip system we

58 ration of new neurons enables plasticity and repair of circuits in the adult brain.

59 xpressed in testes, uniquely blocks excision repair of cisplatin-DNA adducts, 1,2-intrastrand cross-l

60 cAMP-enhanced repair of cisplatin-induced DNA damage was dependent on

61 ecules that may be further optimized for the repair of CNS damage.

62 ore propose that mammalian RAD52 facilitates repair of collapsed DNA replication forks in cancer cell

63 omplex required for chromosome integrity and repair of collapsed replication forks.

64 binding-dependent role that ensures adequate repair of common replication errors.

65 integrated reporters, we demonstrate that HR repair of conventional DSBs is severely compromised in D

66 Repair of CPDs, which we previously showed is intimately

67 BRCA and NHEJ pathways are required for the repair of CX-5461 and CX-3543-induced DNA damage and fai

68 been shown to be implicated in Fe/S cluster repair of cytosolic iron regulatory protein 1 (IRP1), a

69 well as those involved in the prevention and repair of damage (e.g., antioxidant enzymes, HSPs), were

70 Functional repair of damage in the nervous system requires re-estab

71 ular, those caused by HSV1-and mechanisms of repair of damage.

72 process fundamentally important for accurate repair of damaged chromosomes, restart of collapsed repl

73 the DNA damage response (DDR) to mediate the repair of damaged DNA.

74 e a novel hSSB1 regulatory mechanism for the repair of damaged DNA.

75 V-associated malignancies by attenuating the repair of damaged DNA.IMPORTANCE This study expands the

76 owth and development, and is integral to the repair of damaged intestinal mucosa(1-3).

77 shown to be IL-23R(+), demonstrated that DNA repair of damaged melanocytes requires IL-23.

78 ls in mucosal tissues, but it also inhibited repair of damaged mucosa induced by mesenteric ischemia/

79 The markedly enhanced and accelerated repair of damaged muscles following intramuscular delive

80 cidental nerve transection, and facilitating repair of damaged nerves.

81 ressors whose best-characterized function is repair of damaged nuclear DNA.

82 Repair of damaged skeletal-muscle tissue is limited by t

83 activated or M2) macrophages play a role in repair of damaged tissues, including the infarcted heart

84 (flox/flox);Pdgfra-CreER) of Lrp1 attenuates repair of damaged white matter.

85 toblasts during the development, growth, and repair of dentin using mouse molars as a model.

86 The repair of dermal wounds, particularly in the diabetic po

87 etiology of congenital heart defects and the repair of diseased cardiac tissue.

88 gnalling events that mediate recognition and repair of DNA alkylation damage is particularly importan

89 yses implicate both proteins as critical for repair of DNA breaks following transposase cleavage in v

90 of the fluid component controls the rate of repair of DNA breaks per unit volume by repair factors,

91 ably, we found that hyperthermia delayed the repair of DNA damage caused by cisplatin or doxorubicin,

92 model to identify novel factors required for repair of DNA damage inflicted by IR.

93 Maintenance of genome integrity via repair of DNA damage is a key biological process require

94 Accurate repair of DNA damage is crucial to ensure genome stabili

95 demonstrated a DNA device for following the repair of DNA damage produced by a redox-cycling antican

96 rdination of cell cycle progression with the repair of DNA damage supports the genomic integrity of d

97 s a highly conserved protein involved in the repair of DNA damage.

98 stalled replication and its role during the repair of DNA damage.

99 proficient tumors.BRCA2 is essential for the repair of DNA damage; therefore, defects in BRCA2 are as

100 Repair of DNA double strand breaks (DSBs) is key for mai

101 s RAD52 gene and found that HsRAD52 supports repair of DNA double-strand breaks (DSB) by a mechanism

102 Although FANCJ has been implicated in the repair of DNA double-strand breaks (DSBs) by homologous

103 d-joining (cNHEJ) but is dispensable for the repair of DNA double-strand breaks (DSBs) generated duri

104 Not only is Artemis important for the repair of DNA double-strand breaks (DSBs) in NHEJ, it is

105 Repair of DNA double-strand breaks (DSBs) is essential f

106 Repair of DNA double-strand breaks (DSBs) with complex e

107 logous DNA to serve as a template during the repair of DNA double-strand breaks (DSBs).

108 rate pairing of DNA strands is essential for repair of DNA double-strand breaks (DSBs).

109 n essential early step in homology-dependent repair of DNA double-strand breaks (DSBs).

110 l death and reduced homologous recombination repair of DNA double-strand breaks and protein kinase B

111 (MRE11-RAD50-NBS1) complex is essential for repair of DNA double-strand breaks and stalled replicati

112 h specific gene promoters and to promote the repair of DNA double-strand breaks by homologous recombi

113 case that is involved in DNA replication and repair of DNA double-strand breaks by the homologous rec

114 Sae2 promotes the repair of DNA double-strand breaks in Saccharomyces cere

115 Alternative end-joining (alt-EJ) repair of DNA double-strand breaks is associated with de

116 ates, chromosomal DNA, which is used for the repair of DNA double-strand breaks, is exchanged.

117 Top2) cleavage complexes to allow error-free repair of DNA double-strand breaks, thereby conferring c

118 events in wild-type cells are not due to the repair of DNA double-strand breaks.

119 r the proper regulation of homology-directed repair of DNA double-strand breaks.

120 tion provides an important mechanism for the repair of DNA double-strand breaks.

121 pressor complex BRCA1-BARD1 functions in the repair of DNA double-stranded breaks by homologous recom

122 The Fan1 endonuclease is required for repair of DNA interstrand cross-links (ICLs).

123 mia (FA) pathway plays a central role in the repair of DNA interstrand crosslinks (ICLs) and regulate

124 Defects in the repair of DNA interstrand crosslinks (ICLs) are associat

125 ic checkpoint monitors the cohesin-dependent repair of DNA lesions arising from DNA demethylation, wh

126 histone acetylation modulates base excision repair of DNA lesions in chromatin.

127 ulating DNA phosphorylation modes during the repair of DNA lesions.

128 of damaged DNA to promote the signaling and repair of DNA lesions.

129 ADP-ribosyltransferases promote repair of DNA single strand breaks and disruption of thi

130 The repair of DNA strand breaks improves, as do serum protei

131 lear metalloprotease that is involved in the repair of DNA-protein crosslinks (DPCs).

132 ian cells, and a key factor in base-excision repair of DNA.

133 ing its requirement for RAD51 loading during repair of double strand breaks by homologous recombinati

134 res present during homologous recombination, repair of double stranded DNA breaks, and integron recom

135 with machinery responsible for detection and repair of double-strand breaks (DSBs) in DNA, although d

136 tary roles in the DDR; ATM is engaged in the repair of double-strand breaks, while ATR deals mainly w

137 a role in modulating pathway choice for the repair of double-strand breaks.

138 damage response where it participates in the repair of double-strand DNA breaks and in base excision

139 from the genome, it is not required for the repair of double-strand DNA-breaks by homologous recombi

140 Recognition and repair of double-stranded DNA breaks (DSB) involves the

141 coli RecBCD complex, which acts in both the repair of double-stranded DNA breaks and the degradation

142 and homologous recombination compete for the repair of double-stranded DNA breaks during the cell cyc

143 In bacteria, the repair of double-stranded DNA breaks is modulated by Chi

144 n of stalled replication forks, insufficient repair of double-stranded DNA breaks, and improper segre

145 rates with Mre11 and Rad50 to coordinate the repair of double-stranded DNA breaks.

146 any recombination events are associated with repair of double-stranded DNA gaps and/or involve Mlh1-i

147 subtypes have roles in immune modulation and repair of drug-induced damage, and put forward the case

148 Repair of DSBs allows the introduction of targeted genet

149 ts in impaired transcriptional silencing and repair of DSBs by homologous recombination.

150 ations, we propose a mechanism for iterative repair of DSBs by NHEJ.

151 the kinetics of Cas9-mediated generation and repair of DSBs in cells.

152 eotides (ssODNs) to target PCR fragments for repair of DSBs induced by CRISPR/Cas9 on chromosomes.

153 iated resection is a major mechanism for the repair of DSBs with 5' adducts.

154 echanism that coordinates the processing and repair of DSBs with DNA damage checkpoint signalling, pr

155 f the host genome by blocking the homologous repair of DSBs.

156 e of these NHEJ proteins in the mechanism of repair of dsDNA breaks, but interpretations can be confo

157 /SapG as a sigma/anti-sigma pair involved in repair of envelope damage resulting from exogenous sourc

158 The defects in Mre11 compromise the repair of etoposide-induced Top2-DNA covalent complexes,

159 Here we report the repair of gastrointestinal perforation made by a needle-

160 control of the cell cycle allows for timely repair of genetic material prior to replication.

161 We find that repair of genomic lagging strand mismatches occurs bi-di

162 Mesh reinforcement was recommended for repair of hernias >/= 2 cm (grade A).

163 Mesh reinforcement was recommended for repair of hernias >/= 2 cm (grade A).

164 that faithful homologous recombination (HR) repair of heterochromatic DSBs relies on the relocalizat

165 nderstanding the mechanisms of base excision repair of ICLs.

166 M2-like macrophages critically determine the repair of infarcted adult murine heart by regulating fib

167 The immune system orchestrates the repair of infarcted myocardium.

168 ermissive environment.SIGNIFICANCE STATEMENT Repair of injured peripheral nerves remains a critical c

169 pulmonary bypass pump facilitates lifesaving repair of injuries sustained during laser lead extractio

170 mes between men and women being assessed for repair of intact abdominal aortic aneurysm using data fr

171 ovascular aneurysm repair (EVAR) versus open repair of intact abdominal aortic aneurysms have been sh

172 ,921 patients in the United States underwent repair of intact abdominal aortic aneurysms.

173 ion dynamics, coordinate replication-coupled repair of interstrand DNA cross-links, and mitigate conf

174 defined as intraoperative enterotomy, suture repair of intestine, or bowel resection.

175 Overexpressing Beclin 1 improved the repair of IR-induced DSB, but did not restore an autopha

176 In both species the repair of irradiation-induced neuronal DSBs is also quic

177 cruroplasty produces comparable results for repair of large hiatal hernias.

178 ance of CM-ALs (10%) scaffolds with complete repair of large-sized bone defects within 8 weeks.

179 aling cascade allowing cell cycle arrest and repair of lesions.

180 HA) on AEC2s are important for AEC2 renewal, repair of lung injury and limiting the extent of fibrosi

181 odified lipoproteins disrupts the continuous repair of maladapted endothelial cells and triggers inti

182 ibosylation (PARylation) participates in the repair of many forms of DNA damage.

183 he chromosome axes in promoting interhomolog repair of meiotic double-strand breaks by inhibiting int

184 f redundancies for initiating and completing repair of misincorporated ribonucleotides, archaea such

185 ) is a key molecular intermediate during the repair of mitotic double-strand breaks by homologous rec

186 tomycin C (MMC) that correlates with delayed repair of MMC-induced chromosomal DNA damage monitored b

187 robiont' species that contribute to enhanced repair of mucosal wounds.

188 ion tract length has only a modest effect on repair of multiple, dirty DSBs in G2-arrested cells.

189 ANO5, like dysferlin, may be involved in the repair of muscle membranes following injury.

190 emma of myofibers is a necessary step in the repair of muscle tissue.

191 lineage responsible for postnatal growth and repair of muscle.

192 Here we show that the repair of neuroepithelium after lesioning is accompanied

193 Thus, sleep facilitates the repair of neuronal DSBs.

194 ologue, Ddes_1165, that is implicated in the repair of nitrosative damage.

195 st types of genetic modifications, including repair of oncogenic driver mutations.

196 AC is a reasonable alternative to GA for the repair of open globe injuries in selected adult patients

197 t play a central role in the maintenance and repair of our bones are formed from bone marrow myeloid

198 gA's potential to embed mutations during the repair of oxidative damage.

199 r pathway, the main pathway utilized for the repair of oxidative DNA damage, is compromised in Foxo3(

200 educed expression of genes implicated in the repair of oxidative DNA damage.

201 PNKP; an XRCC1 protein partner important for repair of oxidative SSBs.

202 ouble-strand DNA breaks and in base excision repair of oxidized guanine residues (8-oxoguanine) by ai

203 Instead, the faster repair of PDBs underlies resistance, which is associated

204 h appears to be specifically involved in the repair of periplasmic proteins oxidized by hypochlorous

205 lence of PH and difficulties in the surgical repair of PH.

206 em II (PSII) reaction center protein D1 upon repair of photodamaged PSII.

207 ation at S435 is necessary for cAMP-enhanced repair of platinum-induced damage and protection against

208 Compared with non-mesh repair, mesh repair of posterior compartment prolapse was associated

209 ed by homologous recombination (HR)-mediated repair of programmed DNA double strand breaks (DSBs).

210 Homologous recombination (HR) repair of programmed meiotic double-strand breaks (DSBs)

211 al in both initial activation and continuous repair of PSII.

212 S and TDP43 participate in the prevention or repair of R loop-associated DNA damage, a manifestation

213 identified as having an unspecified role in repair of radiation damage and, more specifically, DNA d

214 transformation; however, its contribution to repair of radiation-induced DSBs has not been characteri

215 g schemes, and enable the identification and repair of recoding at idiosyncratic positions in the gen

216 physiological cell cycle progression for the repair of replication-associated DNA damage and protecti

217 ctomies have become increasingly used in the repair of retinal detachment related to proliferative vi

218 n-the-bag intraocular lens dislocation after repair of retinal detachment were evaluated.

219 f cataract surgery in patients with previous repair of retinal detachment.

220 median, quartiles): 57 years (47, 63)] after repair of ruptured anterior communicating artery aneurys

221 Precise genome-editing relies on the repair of sequence-specific nuclease-induced DNA nicking

222 ulate cell fate decisions and the growth and repair of several tissues.

223 Although this study focuses on the repair of severely injured skeletal muscle, magnetically

224 In repair of single-nucleotide gaps, however, the presence

225 Repair of skeletal muscle after sarcolemmal damage invol

226 Normal repair of skeletal muscle requires local expansion of a

227 ve been known only to initiate base excision repair of small adducts by extrusion from the DNA helix.

228 over a novel role for the Shu complex in the repair of specific MMS-induced DNA lesions and elucidate

229 Repair of spines, important for both buoyancy and feedin

230 tically normal gametes and is dependent upon repair of SPO11-induced double-strand breaks (DSBs) by h

231 B) repair, DNA interstrand crosslink repair, repair of stalled replication forks and DNA end joining-

232 s in double-strand break repair, rescue, and repair of stalled replication forks and meiosis.

233 Aberrant repair of stressed replication forks can result in cell

234 The repair of such DSBs is critical to the survival of cells

235 S1(S432) with TRF2 promotes alternative-NHEJ repair of telomeres lacking POT1-TPP1.

236 Classical-NHEJ-mediated repair of telomeres lacking TRF2 requires phosphorylated

237 y-five patients aged median 12.0 years after repair of tetralogy of Fallot and similar lesions were s

238 idity and mortality after transannular patch repair of tetralogy of Fallot.

239 C-induced lesions and facilitated error-free repair of TFO-ICLs in mouse fibroblasts.

240 Surgical repair of TGA performed in the developing world is assoc

241 Repair of the 2nd Fob1 binding site (Ter1) dramatically

242 assessment of patients awaiting endovascular repair of the abdominal aorta is little evaluated.

243 le and contract autonomously, enabling local repair of the actomyosin network.

244 Repair of the alveolar epithelium is critical for clinic

245 t recommendations for the timing of surgical repair of the aortic root aneurysms may be overly aggres

246 nked actin gel that can lead to a successful repair of the aperture.

247 anded CAG repeats are prone to breakage, and repair of the breaks can cause repeat contractions and e

248 e useful for future investigations about the repair of the carboxymethylated DNA lesions and about th

249 he past years, stem cell transplantation for repair of the CNS has received increasing interest, alth

250 ak which is required for surgical/endoscopic repair of the CSF fistula.

251 ry arrest of the cell cycle to allow for the repair of the damage.

252 and alveolar type 1 cells (AT1s) during the repair of the damaged alveolar epithelium.

253 s for immune modulation, neuroprotection, or repair of the damaged central nervous system in multiple

254 e show that TALENs mediate homology-directed repair of the DDX4 locus on the Z sex chromosome at high

255 Androgens regulate scarless repair of the endometrial "wound" in a mouse model of me

256 that subsequently coordinate ICL removal and repair of the ensuing DNA double-stranded break by homol

257 Although genetic repair of the FD-associated mutation reversed early deve

258 cal and structural remodelling, and impaired repair of the heart in murine models, all of which may i

259 that TWINKLE is involved in recombinational repair of the human mitochondrial DNA.

260 Surgical repair of the lip is the only treatment and is usually p

261 demonstrate that HMGB4 specifically inhibits repair of the major cisplatin-DNA adducts in TGCT cells

262 uld encounter during replication or possibly repair of the mitochondrial genome and how well it toler

263 Following surgical repair of the mitral valve, the dyspnea and palpitations

264 hways that bypass such obstacles, postponing repair of the offending damage to complete the cell cycl

265 Here, we review research on regeneration and repair of the optic system.

266 t carries faithful information to direct the repair of the other.

267 protein Rubisco activase (Rca) in metabolic repair of the photosynthetic enzyme Rubisco, a complex o

268 ricate biomimetic cellular scaffolds for the repair of the tissue.

269 rmation on the NTS and transcription-coupled repair of the transcribed strand (TS).

270 bed genes, Mfd played a role in preferential repair of the transcribed strand.

271 Over a time course, we measured repair of the UV-induced damage of cyclobutane pyrimidin

272 an undetermined way) with ATM to facilitate repair of these double-strand breaks by the classical no

273 Radical repair of these gene deficits via genome engineering is

274 viding a potential alternative mechanism for repair of these lesions in bacteria.

275 enome instability, but how the formation and repair of these lesions is affected by the genomic lands

276 Repair of these lesions via base excision repair (BER) p

277 Accordingly, HR and NHEJ compete for repair of these paired nicks, but, surprisingly, only wh

278 r that is capable of quantifying the rate of repair of thymine glycol in a variety of human cells wit

279 The repair of TMZ-induced DNA damage by O-6-methylguanine-DN

280 implicating homologous recombination for the repair of Top1-induced damage at ribonuclelotide sites.

281 model for the generation, stabilization and repair of trans-endothelial apertures.

282 ation and transcription and facilitating the repair of transcribed DNA.

283 ins normally contribute to the prevention or repair of transcription-associated DNA damage.

284 To determine whether delayed repair of traumatic canalicular laceration affects the f

285 hibiting the TGF-beta pathway, increases the repair of ultraviolet (UV)-induced DNA damage in E-cadhe

286 TL3 catalytic activity, cells showed delayed repair of ultraviolet-induced cyclobutane pyrimidine add

287 Repair of ultraviolet-induced DNA damage was normal in t

288 cally acetylated H3K14 or H3K56 and measured repair of uracil and single-nucleotide gaps.

289 rization of different roles of PARP-1 in the repair of UV-damaged DNA and also allow the study of nor

290 mer-containing ssDNA oligos generated during repair of UV-induced damage to study that process at bot

291 oles of UvrD helicase and Mfd translocase in repair of UV-induced damage.

292 Formation and repair of UV-induced DNA damage in human cells are affec

293 crucial role of E-cadherin in efficient DNA repair of UV-induced DNA damage, identify a new link bet

294 n structure, thereby promoting efficient DNA repair of UV-induced lesions.

295 ween vaginal and, separately, abdominal mesh repair of vaginal vault prolapse compared with vaginal n

296 gumin 53 (MG53) participates in the membrane repair of various cells, and skeletal muscle is the majo

297 known as M2) macrophages are involved in the repair of various types of organs.

298 ied, but there are few studies of endogenous repair of viral DNA.

299 ( approximately 10) in late prophase I, the repair of which is inhibited by the presence of HORMAD1/

300 The repair of wounds through collective movement of epitheli