ライフサイエンスコーパス: repair response

1 ivating an endogenous, germline-specific DNA repair response.

2 n to be the initiator of the endogenous bone repair response.

3 romatic regions of the genome and in the DNA repair response.

4 s Mdm2 to the Mre11-Nbs1-Rad50-regulated DNA repair response.

5 the initial stages of the wound defense and repair response.

6 to examine a potential role for WRN in this repair response.

7 checkpoints is essential to a robust damage-repair response.

8 l was adapted for mice to study the fibrotic repair response.

9 t growth factor mediators participate in the repair response.

10 ouble-strand breaks (DSBs) and trigger a DNA repair response.

11 idermis are the primary signal inducing this repair response.

12 ment with fibronectin restored the epidermal repair response.

13 ted gene 45, two molecules linked to the DNA repair response.

14 ebride the site of injury and coordinate the repair response.

15 man skin and is an important part of a wound repair response.

16 blebbing, lysosomal exocytosis, and membrane repair response.

17 ges are critical in orchestrating the tissue-repair response.

18 int signaling due to the double-strand break repair response.

19 ritical regulator of the cellular DNA damage repair response.

20 which might represent an intrinsic host CNS repair response.

21 ng in a saturation of DNA-PK-mediated damage repair response.

22 ing potential mechanisms for this endogenous repair response.

23 hase checkpoint and for efficient DNA damage repair response.

24 ke in both central nervous system injury and repair responses.

25 thesis and degradation are key to initiating repair responses.

26 tory responses and less well-understood host repair responses.

27 d control intestinal inflammation and injury/repair responses.

28 of genes involved in inflammation and tissue-repair responses.

29 an important role in liver regeneration and repair responses.

30 NM uptake and, thus, varying DNA damages and repair responses.

31 l cells can create scars that inhibit neural repair responses.

32 persistent inflammation and defective tissue repair responses.

33 evealed Clld7 target genes that regulate DNA repair responses.

34 regarding the potential function of P2RX7 in repair responses.

35 required for appropriate DSB recruitment and repair responses.

36 ment for p53 in regulating the base excision repair response, a novel finding of great potential impo

37 e of differentiated tissues and enhances the repair response after injury.

38 ll recruitment during the nascent biological repair response after myocardial damage.

39 ation is an essential process for mounting a repair response after myocardial infarction (MI).

40 at a single immune receptor is essential for repair responses after SCI, and the potential mechanisms

41 0/Nbs1 DNA repair complex, and a delayed DNA repair response all indicate that Runx2 deficiency leads

42 l functions of inflammatory cells during the repair response and compare data from other tissues, the

43 EcoRI methyltransferase induces the SOS DNA repair response and greatly reduces viability of recA56,

44 K4a in homologous recombination-mediated DNA repair response and imply p16INK4a status as an independ

45 n-resident T cells in the UVR-associated DNA repair response and underscore the importance of skin-re

46 e diseases are driven by dysregulated tissue repair responses and are a major cause of morbidity and

47 ir, and the connection between defective DNA-repair responses and specific neurological disease.

48 ear site involved in DNA damage recognition, repair response, and cell cycle checkpoint activation.

49 iated with increased DNA damage, reduced DNA repair responses, and elevated cellular senescence.

50 ith wild-type bone marrow showed an improved repair response, as seen by a profound increase in proli

51 serve as an important mediator of growth and repair responses, associated with development of angioge

52 to the occurrence of inflammatory and injury/repair responses at different mucosal sites.

53 ng the activation of aberrant DNA damage and repair responses at telomeres.

54 To execute an appropriate repair response, BER components must be distributed to a

55 postischemic mouse kidneys and compared the repair response between control (wild-type) and muMT (B

56 te tumor suppressor that accelerates the DNA repair response, binds to androgen receptor at the ERG g

57 ssue injury is unlikely to contribute to the repair response but rather is a participatory factor in

58 Thus, the lysosomal repair response can also protect cells against pathogens

59 a misdirected macrophage-orchestrated tissue repair response can result in chemoresistance, but in ot

60 rleukin-1 family of cytokines in the barrier repair response, cytokine production was stimulated in a

61 Repair responses define the ultimate outcomes of liver d

62 iciency in fibrous tissues results in a poor repair response due to the accumulation of aggrecan in t

63 Moreover, chondrocytes exhibit a potential repair response following this procatabolic stimulus suc

64 uences both susceptibility and nature of the repair responses following injury.

65 This is the first characterization of a DNA repair response from expression of a non-long terminal r

66 t tumors secrete factors that elicit a wound-repair response from TAMs and TANs and that this respons

67 he regulation of the DNA double-strand break repair response, genomic stability, and transformation t

68 inoglycoside damage paradigm, the epithelial repair response halted.

69 of the vertebrate nervous system and tissue-repair responses has hindered identification of the prec

70 stress induces apoE synthesis as part of the repair response; however, when apoE4 is expressed in neu

71 gion of cardiac infarction and can augment a repair response in damaged tissue.

72 ased ENMs induced relatively weak DNA damage repair response in E. coli, but more severe DNA double s

73 n the form of selenomethionine induces a DNA repair response in normal human fibroblasts in vitro, an

74 KO tubular epithelial cells had an increased repair response in vitro, as seen by an increased abilit

75 The Ca(2+) flux triggers a wounded membrane-repair response in which internal vesicles, including ly

76 target cell that triggers a wounded membrane repair response in which lysosomes and endosomes donate

77 in the personalized management of injury and repair responses in critical illness.

78 lay an important role in restricting dynamic repair responses in mammalian vestibular epithelia.

79 ng wing disc appears to cause non-autonomous repair responses in the neighbouring wild-type epitheliu

80 R) in asthmatic bronchial mucosa and studied repair responses in vitro.

81 w a possible mechanism for the inducible DNA repair response, in which enhanced repair complex format

82 toma SK-N-SH revealed that PGJ2 triggered a "repair" response including increased expression of heat

83 of genes involved in inflammatory and tissue-repair responses, including neutrophil-specific chemokin

84 ng RNAiR5-bearing vectors showed far greater repair responses: increased neuronal proliferation, and

85 radiation-induced DNA damage, integrate DNA repair responses into the cell cycle programme.

86 elial cells, triggering damage signaling and repair response involving ATM.

87 is and other stratified epithelia triggers a repair response involving the rapid induction of several

88 , and one of the key signals initiating this repair response is a decrease in the concentration of ca

89 The cell wound repair response is an example of how specific pathways c

90 standing the variable central nervous system repair response is crucial to identifying "at risk" infa

91 A conserved DNA repair response is defective in the human genetic illnes

92 et-cell membrane integrity by triggering the repair response is necessary for target cells subjected

93 The induction of a DNA repair response is protective against Abeta42 toxicity,

94 However, this endogenous repair response is suboptimal and may account for the pe

95 for ATM/ATR activity, we found that the DSB repair response is surprisingly dynamic at the site of D

96 Mice lacking SFRP1 exhibited a rapid repair response leading to aberrant proliferation of dif

97 Triggering of the membrane repair response may help cells to replace distorted plas

98 ers following seizures suggests that the DNA repair response may not be sufficient to prevent excitot

99 Components of the cellular DNA damage repair response may represent potential targets for anti

100 s likely a key component of inflammatory and repair response mechanisms, and involves the processing

101 The repair response must re-establish the epithelial barrier

102 se alterations may contribute to the delayed repair response of aging.

103 The purpose of this study was to compare the repair response of bioactive glass synthetic bone graft

104 pulation of oxygen levels might equalize the repair response of each tissue, we exposed mice to hyper

105 itope in hip OA cartilage indicates a lesser repair response of hip OA compared with knee OA cartilag

106 Therefore, SigG does not control the DNA repair response of M. tuberculosis H37Rv.

107 tive and qualitative biosensor of the injury repair response of the heart.

108 microcephaly genes implicated in either DNA repair responses or centrosomal function may act in comm

109 such as cell-cycle control, DNA-damage and -repair responses, p53 and HIF1alpha.

110 Hepatic regenerative/tissue repair responses prevail during the later stages of acut

111 but not hypertrophy, suggests that apoJ is a repair response protein.

112 unabated, MRN elicits a double-strand break repair response that blocks viral DNA replication and li

113 stromal, and BEC results in a dysmorphogenic repair response that eventually leads to cirrhosis.

114 a heightened basal and wound site DNA damage/repair response that is also common to classical regener

115 ion of the permeability barrier stimulates a repair response that leads to the restoration of barrier

116 tic cells evoke a persistent pseudo-membrane repair response that likely redistributes lysosomal-deri

117 nct processes: 1) induction of an epithelial repair response that maintains the protective barrier an

118 These DSBs induce an endogenous DSB repair response that results in small insertions or dele

119 apoptosis could activate a "pseudo"-membrane repair response that results in the fusion of lysosomes

120 geted pharmacologically to modulate survival/repair responses, the transport inhibitor N-(4-hydroxyph

121 al role in regulating the early inflammatory repair response to acute myocardial injury by facilitati

122 BM SPC recruitment is a repair response to dimethylnitrosamine liver injury in r

123 n-edited strand, manipulate the cellular DNA repair response to favour desired base-editing outcomes,

124 The tissue repair response to hypoxic stimuli during wound healing

125 ssion of 394 transcripts associated with the repair response to injury, including many epithelium-lik

126 histones, are likely to cripple the cellular repair response to promote cell death in this novel casp

127 e I (TOP1) has been suggested to be a unique repair response to TOP1-mediated DNA damage.

128 ter are related to aberrant regeneration and repair responses to acute death of premyelinating late o

129 oliferation and ductular reaction, which are repair responses to cholestatic injury.

130 se, but also modulates tissue remodeling and repair responses to endogenous ligands released during l

131 regulating damage-associated checkpoint and repair responses to HSP90 inhibitors, and identify BRCA1

132 ed individuals often demonstrate exaggerated repair responses to injury.

133 ution of macrophage HO-2 to inflammatory and repair responses to injury.

134 s are required for cell cycle checkpoint and repair responses to ionizing radiation, implicating ubiq

135 , but relatively little role for p21, in DNA repair responses to UV radiation.

136 Here we show that the beneficial DNA repair response triggered by these two genome caretakers

137 le arrest in G2/M phase and an increased DNA repair response were observed in IR-exposed miR-15b/16-2

138 (MMS), suggesting that PARP activity and DNA repair responses were impaired.

139 escence do not exhibit a BRCA1-dependent DNA repair response when exposed to DNA damage.

140 catalytic activity to mount a cell survival repair response, whereas persistent PARP-1 hyperactivati

141 TM is primarily required for the meiotic DSB repair response, which includes functions in DNA damage

142 Stress pathways coordinate a cytoprotective repair response, while simultaneously initiating signali

143 respiratory viruses may impede or alter the repair response will be important areas of research for

144 However, this damage also stimulates DNA repair responses with subsequent blocks to cell prolifer

145 The loss of auditory hair cells triggers repair responses within the population of nonsensory sup