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1 (dsDNA) genome with large inverted terminal repeats.
2 orms with three (3R) or four (4R) MT binding repeats.
4 tary intakes of arginine were assessed using repeated 24-hour recalls that were administered througho
6 otide containing a sequence of four six-base repeats (4 x 6), forming a matrix of layers that are org
7 u isoforms containing either 3 (3R-Tau) or 4 repeats (4R-Tau) play an important role both during brai
8 e well-studied eukaryotes possess a tandemly repeated 7-amino-acid sequence, called the canonical CTD
9 that amino acid substitutions in Fn-binding repeat-9 can significantly affect bond strength and infl
10 trongly interactive: it is more difficult to repeat a response in the context of a changing task-set,
11 at this Kirkendall cavitation process can be repeated a number of times to gradually inflate the holl
13 stinct consequences of changes in telomerase repeat addition processivity and expression level on tel
17 ng and multiple-locus variable-number tandem-repeat analysis (MLVA) of selected strains was performed
18 d girl was referred to our hospital owing to repeated anaphylactic reactions induced by exercise afte
20 binding oligomerization domain, leucine rich repeat and pyrin domain containing 1 (NLRP1), NLRP3, and
21 evidence that long patterns of activity are repeated and transmitted to downstream neurons, suggesti
22 aging (pac) site containing two 21-bp direct repeats and a major terminase cleavage site in the phage
24 e regulatory elements in their long terminal repeats and differed in a helical segment of envelope in
25 ional regulatory elements is associated with repeats and non-allelic homologous recombination and fur
27 lassified them into groups, including tandem repeats and Staphylococcus aureus repeat (STAR)-like ele
28 tially interacts with the leader-side CRISPR repeat, and finally, it catalyses a nucleophilic attack
32 study, we assess the impact of large tandem repeat arrays on the recombination rate landscape in an
39 dded value of incorporating information from repeated blood pressure and cholesterol measurements to
41 ompassing the homeodomain and the tryptophan repeat can support LIF-independent colony formation.
43 lance of evidence indicates that the (G4C2)n repeat causes toxicity and neurodegeneration via a gain-
51 enger RNA in MSN subtypes was assessed after repeated cocaine using D1-Cre-RiboTag and D2-Cre-RiboTag
53 profile two such genes, Delta/Notch-like EGF repeat containing (Dner) and nuclear factor I/A (Nfia),
54 sed Gsk3beta activation, ii) beta-transducin repeat containing E3 ubiquitin protein ligase nuclear ac
55 binding within the megabase, alpha-satellite repeat-containing centromeres of 23 human chromosomes.
56 pivotal role for the R-spondin/leucine-rich repeat-containing G protein-coupled receptor 4 (LGR4) ax
57 d sgRNAs enable multicolour labelling of low-repeat-containing regions using a single sgRNA and of no
58 crop plants have highly variable ploidy and repeat content, the performance of GBS analysis software
59 repair (BER) is responsible for causing CAG repeat contractions downstream of Fcy1, but not fragilit
61 of side chains/number of norbornene backbone repeats) could be straightforwardly controlled by the ma
63 ammalian cells, which have dimeric or tandem-repeated CRDs enabling multivalency for various function
64 ered regularly interspaced short palindromic repeat (CRISPR)-Cas9 system and measured the quantities
65 ered regularly interspaced short palindromic repeat (CRISPR)-Cas9 technology, gene-specific small int
66 ered regularly interspaced short palindromic repeats (CRISPR)-Cas9 platform for in situ high-content
67 ered regularly interspaced short palindromic repeats (CRISPR)-enzymatically inactive Cas9 in MVM-infe
68 ered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated gene9 (CRISPR/Cas9) gene editi
69 (clustered regularly interspaced palindromic repeats/CRISPR-associated) homology-directed repair gene
70 onclusion Positive rates for large polyps at repeat CT colonography screening (3.7%) were lower compa
71 caused by the expansion of CTG trinucleotide repeats ((CTG)exp) in the 3' untranslated region of the
72 etermine whether patients who had a positive repeated culture was predictive of worse clinical outcom
73 0% and double the full discharge capacity in repeated cycles compared to the compact MWCNT electrode
74 eater insulin release was also observed over repeated cycles of photoinduction without adverse effect
76 B canonical signaling by Notch-4/Int3 is ANK repeats dependent, Rbpj-independent, and is mediated by
77 ted for Q-quadruplexes formed from telomeric repeats depending on DNA length and ion solution conditi
79 tructures have the same helical symmetry and repeat distance and nearly identical folds of correspond
80 inked GGA motifs in the stem region of TGGAA repeat DNA act as hot spots to facilitate the transition
81 cond Ig-like polycystic kidney disease (PKD) repeat domain (PKD2) present in the ectodomain of AAVR.
82 to directly interact with Tetratricopeptide Repeat Domain 5 (TTC5), a p53 co-factor, and genetic kno
86 Qa, immediately upstream of the SNARE heptad-repeat domain, is required for normal fusion activity wi
88 volve nucleotide-binding domain-leucine-rich repeat domain-containing proteins to recognize specific
89 26 (sup-26) and NHL (NCL-1, HT2A, and LIN-41 repeat) domain-containing-2 (nhl-2), encode RNA-binding
90 nt mice lacking the SH3 and multiple ankyrin repeat domains 3 (SHANK3B) scaffolding protein, defectiv
91 s containing HEAT (Huntingtin/EF3/PP2A/Tor1) repeat domains whose origin and distribution have not ye
92 t to a single-dose treatment (75 mg/kg/day), repeated doses of peramivir rescued BALB scid mice from
98 Among participants in the SCD-HeFT who had a repeated EF assessment during the course of follow-up, t
100 y system permits mapping through subtelomere repeat element (SRE) regions to unique chromosomal DNA w
103 eric CTCF-binding sites to generate telomere repeat-encoding RNA (TERRA), but the role of transcripti
104 ssion diversity resulting from adaptation to repeated episodes of acute hypoxia in a premalignant pro
105 of model variants: how to model time to the repeated events (calendar time, gap time, elapsed time);
108 story of admixture and identifies signals of repeated evolutionary selection, some of which may be li
109 anticipation in families carrying a C9orf72 repeat expansion by means of a decrease in age at onset
117 ating interaction between gender and C9orf72 repeat expansions demonstrated that the reduced survival
118 n vitro and large-scale trinucleotide (GAA)n repeat expansions in vivo, implying failed phosphate-ste
126 ican lineages were complex, involving either repeated gene flow among geographically disparate groups
129 ous recombination and furthermore that young repeats have also contributed to the p300-bound regulato
132 elopment of anaphylaxis in C57BL/6 mice upon repeated i.p. dosing because of an anti-idiotypic anti-d
133 racellular loops of the CaValpha1 protein in repeats I (IS1S2 and IS5S6), II (IIS5S6), and III (IIIS5
139 nvestigate perception of stimuli that either repeated in the same location (two-flash fusion) or move
140 )n repeats in myotonic dystrophy, and (CGG)n repeats in fragile X syndrome, are also subject to doubl
141 inucleotide repeat sequences, such as (GAA)n repeats in Friedreich's ataxia, (CTG)n repeats in myoton
142 an interact with hAgo via three of the GW/WG repeats in its Argonaute-binding domain: motif-1, motif-
143 single-domain enzymes, they appear as tandem repeats in large polypeptides we refer to as CSRPs (copp
144 GAA)n repeats in Friedreich's ataxia, (CTG)n repeats in myotonic dystrophy, and (CGG)n repeats in fra
148 codes an amino acid in the tetratricopeptide repeat, in OGT (759G>T (p.L254F)) that segregates with X
149 nature composed of short deletions in tandem repeats; in the specific case of ribonucleotide-initiate
151 Here we show that DIM-2 can also mediate repeat-induced point mutation (RIP) of repetitive DNA in
153 formation and reveal two mechanisms for CAG repeat instability: one mediated by cytosine deamination
154 od of elastic net regularization, which uses repeated internal cross-validation to select variables a
156 rs specific proteins, and translation of CGG repeats into a polyglycine-containing protein, FMRpolyG.
158 d with recombinant TNFalpha in vitro, and by repeated intrathecal injection of recombinant TNFalpha i
166 fibrils possess distinct morphology made of repeating LFAO units that could be regenerated upon soni
167 apacities, we challenged male Wistar rats to repeated lipopolysaccharide instillations, associated or
168 Together, our data suggest that the heptad repeat LIZ contributed to TM-TM association and is impor
171 iptional activity of the viral long terminal repeat (LTR) from Vpr-deficient proviruses was significa
172 ation with specific classes of long terminal repeat (LTR) retrotransposons and organize into large lo
173 typically resembles endogenous long terminal repeat (LTR) sequences, pointing to a select role of BRD
175 respiratory distress syndrome was induced by repeated lung lavages and injurious mechanical ventilati
176 nique intervention in primary care settings (repeated mailing, an electronic health record best pract
179 ted by conventional venepuncture, permitting repeated measurements from the same individuals to monit
182 rdial injury cohort (n=15; P<1.33E-04, 1-way repeated measures analysis of variance); >90% were direc
183 4-hour postinfusion measurements of both T2 (repeated measures analysis of variance, P = .025) and T2
184 which used a linear mixed effects model for repeated measures and represented the mean treatment eff
185 tatistical analyses, including mixed effects repeated measures models and logistic regression, reveal
186 dels in capturing mediated associations when repeated measures of exposure and mediator are available
187 We used a 3-level multilevel model nesting repeated measures of outcomes within participants, who w
188 metric tests compared baseline data, whereas repeated-measures analyses assessed treatment change.
189 ons or chi(2) or Fisher exact tests and with repeated-measures analysis of variance to compare groups
190 ences were observed in [(11)C]NPA DeltaBPND (repeated-measures analysis of variance, F1,26 = 1.9, p =
191 ll effect sizes of change values; and used a repeated-measures ANOVA to assess pre- to postinterventi
193 NT This is one of the first studies to use a repeated-measures imaging procedure to explore the diurn
195 7R C-terminus is differentially modulated by repeated morphine treatment and has no bearing on normal
196 proteins) zinc finger protein binds these GA repeat motifs, increases chromatin accessibility, enhanc
198 cal pairs in (CAG)n and (GAC)n trinucleotide repeats (n = 1, 4) and the consequent changes in the ove
200 stress indicating that natural variation in repeat numbers may optimize the chance for survival.
201 ing statistical controls, we determined that repeats occurred more often than would be expected from
202 rprisingly, there was no correlation between repeat occurrence and classical network states such as t
203 ovide evidence that breakage at expanded CAG repeats occurs due to R-loop formation and reveal two me
206 s (baseline; PETco2 at 50, 55, and 60 mm Hg; repeat of PETco2 at 60 mm Hg; and repeat of baseline).
207 ing solutions of SELP 815K (which contains 6 repeats of blocks comprised of 8 silk-like units, 15 ela
208 NATs to be encoded in solitary long terminal repeats of the ERV9/LTR12 family, which are epigenetical
209 dues 60-550 that indicates that the TPR-like repeats of the M-region extend to residue 137 and that r
213 doubled, the odds for trainee supervision or repeated patient examination was reduced by 45.3% (95% C
215 vision in threespine stickleback during the repeated postglacial colonization of clearwater and blac
219 family, exemplified by the serine-aspartate repeat protein D (SdrD), which serve key roles in coloni
220 pleckstrin homology domain and leucine-rich repeat protein phosphatase 1 (PHLPP1) as a regulatory ph
221 re and stepwise folding coevolved in ancient repeat proteins and were retained as a functional pair d
226 distinguish between folded and unfolded EGF repeats raised the possibility that they participate in
228 rovide further support for the occurrence of repeated reactivation of latent HSV1 in the brain in AD
230 malian genomes are replete with interspersed repeats reflecting the activity of transposable elements
231 al and cell membranes together as two heptad-repeat regions refold to form a six-helix bundle structu
235 xapeptide from the third microtubule-binding repeat resulted in a peptide that rapidly forms fibrils
237 rction (HR: 1.47; 95% CI: 1.23 to 1.78), and repeat revascularization (HR: 5.64; 95% CI: 4.67 to 6.82
239 afting was associated with a reduced risk of repeat revascularization and an improvement in long-term
241 ardial infarction, cardiovascular death, and repeat revascularization cumulative incidence was 2.3% (
244 a model that shows how pairings between long repeated sequences could be efficiently rejected even th
245 Further research should examine whether repeated shocks of this kind lead to substantial increas
246 additional proteins, including the telomeric repeat single-stranded DNA-binding protein Teb1 and its
250 es contain mainly SCEN-like single satellite repeat (Ss1) and several Ty3/gypsy retrotransposon-relat
252 and efficient genotyping of simple sequence repeats (SSRs) constitutes the basis of SSRs as an effec
254 ca sexta grew faster when consuming inverted-repeat stable transformants (irAGO8) plants but did not
257 on of DOBV before 2010 can be interpreted as repeated stochastic fadeouts after multiple introduction
259 Identifying large expansions of short tandem repeats (STRs), such as those that cause amyotrophic lat
260 The functional relevance of the inverted repeat structure (IR/DR) in a subgroup of the Tc1/marine
261 (SLC26Dg and UraA), to have a 7 + 7 inverted repeat structure with anion transport initiated by chlor
262 cteria LexA-binding motif has unusual direct-repeat structure, and comparative analyses reveal sequen
264 rified human telomerase catalyzes processive repeat synthesis, which could restore the full 100 nucl
265 ered regularly interspaced short palindromic repeats) system protects archaea and bacteria by elimina
266 o be cost-effective in those at high risk of repeated systemic sting reactions and/or impaired qualit
270 s "liquid biopsy" is quicker and more easily repeated than tissue biopsy, yields real-time informatio
272 mparison with data of denatured proteins, we repeated the assignment in 7 M urea (pH 2.3) and in DMSO
273 pled plots that were established in 1972 and repeated the full C inventory by analyzing more than 4 d
277 CHIP monomer consists of a tetratricopeptide-repeat (TPR), helix-turn-helix (HH), and U-box domain.
284 cture that we term an "eta-helix" due to its repeating turns, which are highly reminiscent of peptide
285 ur nonconsensus variants within a single IR1 repeat unit, including a stop codon in the EBNA-LP gene.
287 In-depth genome-wide comparison of genes and repeats unveiled that the copy numbers of NLRs were grea
290 2.93; confidence interval: 1.76-4.90), and, repeat variants variable number tandem repeat (VNTR) 4 D
293 and, repeat variants variable number tandem repeat (VNTR) 4 DRD4 (odds ratio: 1.66; confidence inter
296 GC content, each containing a long inverted repeat with one or two protein-coding genes and conserve
297 eactivated Cas9 to either the DNA or the RNA repeats with therapeutic potential for several diseases.
298 t the end of the study, echocardiography was repeated, with additional RV pressure-volume measurement
299 line protocol in which PET examinations were repeated within 2 d of each other with no intervening tr
300 unbounded evolution as patterns that are non-repeating within the expected Poincare recurrence time o
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