ライフサイエンスコーパス: reperfuse

1 for 1 hour to 7 days, to allow the retina to reperfuse.

2 ow, to determine areas of the brain that had reperfused.

3 (i.e., a 75% reduction in coronary flow) and reperfused.

4 pared with controls or livers stored but not reperfused.

5 o the previously ischemic area that has been reperfused.

6 No placebo-treated pig reperfused.

7 15 mins of no-flow ischemia and subsequently reperfused.

8 f the liver was clamped for 75 mins and then reperfused.

9 Muscles were reperfused 10 minutes after the onset of ischemia relate

10 In reperfused acute MI, accurate determination of infarct s

11 T (GST is glutathione S-transferase) using a reperfused acute myocardial infarction (AMI) rat model.

12 In the CYCLE (CYCLosporinE A in Reperfused Acute Myocardial Infarction) trial, a single

13 In patients with reperfused acute myocardial infarction, the area of redu

14 ntions, coronary artery bypass grafting, and reperfused acute myocardial infarction.

15 flow and not viability in a canine model of reperfused acute myocardial infarction.

16 ps can reliably quantify AAR and final IS in reperfused acute myocardial infarction.

17 te in reducing infarct size in patients with reperfused acute myocardial infarction; unfortunately, f

18 IPC inhibits initial MPTP opening in hearts reperfused after 30 min global ischaemia, and subsequent

19 D) was kept persistently occluded (n = 6) or reperfused after 40 minutes (n = 6) in rabbits.

20 d images relate to functional recovery after reperfused AMI.

21 combinant Gal-1 attenuated cardiac damage in reperfused AMI.

22 s in vivo, dose-dependent neuroprotection in reperfused and nonreperfused cerebral ischemia at clinic

23 99mTc glucarate uptake in reperfused and nonreperfused infarct centers was 28 and

24 nfarcts were visualized within 10 minutes in reperfused and within 30 minutes in nonreperfused corona

25 Hearts were then reperfused, and functional and metabolic indices of trea

26 After 5 min of ischemia, the animal was reperfused, and the ChR2-mediated response mostly recove

27 so infused at 5, 10, and 20 min of ischemia, reperfused, and then prepared for histochemical staining

28 with sham-operated controls, myocardium from reperfused animals had higher levels of free radicals, i

29 kage of serum albumin, increased in ischemic-reperfused animals when compared with time-matched sham

30 In the first 8 weeks after a large, reperfused anterior MI, %S improved in the apex, midante

31 Ex vivo images revealed tracer uptake in the reperfused area (ischemic to normal count ratio=2.7+/-0.

32 The washout of (99m)Tc-GLA from the ischemic-reperfused area in IR90 was significantly slower than th

33 proportion of the perfusion lesion that was reperfused at 24 hours on perfusion-weighted magnetic re

34 against such injury of ischemic tissue when reperfused at the return of spontaneous circulation.

35 e high-glycogen hearts increased to 89% when reperfused before contracture and to 56% when reperfused

36 ing reperfusion correlated strongly with the reperfused blood flow.

37 ld University of Wisconsin (UW) solution and reperfused briefly with physiological buffer containing

38 herwise, after cold storage, the livers were reperfused briefly with physiological buffer containing

39 afts were stored for 6 hours at 4 degrees C, reperfused by a veno-venous circuit from an anesthetized

40 We determined that transplants were reperfused by connection of recipient vessels to donor v

41 h ST-segment-elevation myocardial infarction reperfused by primary angioplasty (<12 hours after sympt

42 In total, 738 STEMI patients reperfused by primary angioplasty were enrolled in 8 cen

43 d clinical outcome in STEMI patients who are reperfused by primary angioplasty.

44 admission in 411 consecutive STEMI patients reperfused by primary angioplasty.

45 The patients were reperfused by primary PCI <12 h after symptom onset.

46 In a large, multicenter STEMI population reperfused by primary PCI, CMR markers of myocardial dam

47 ent-elevation myocardial infarction patients reperfused by primary percutaneous coronary intervention

48 40 STEMI patients reperfused by primary percutaneous coronary intervention

49 The MCA was reperfused by removing the suture in 40 min.

50 n of MCP-1 mRNA only in ischemic segments of reperfused canine myocardium.

51 In reperfused cerebral ischemia, mean infarct volume was re

52 In the setting of reperfused chronic MI, the TEI approaches 50% before con

53 In the setting of reperfused, chronic myocardial infarction (MI), the rela

54 Hearts in group 1 were ischemic/reperfused controls without L-arginine treatment.

55 information on their impact on the ischemic/reperfused coronary circulation is available.

56 as demonstrated in relation to the number of reperfusing defects (0 = 7%, 1 to 2 = 15%, >3 = 20%, p =

57 ty of inducible VT in patients who have been reperfused early after ST-segment-elevation myocardial i

58 Because these regions are reperfused, essentially all weakly metastatic clone A an

59 r (LV) remodeling in the first 8 weeks after reperfused first anterior myocardial infarction (MI).

60 Twenty-three patients with a reperfused first MI were studied.

61 single-vessel disease 162 +/- 62 days after reperfused first MI.

62 an age of 53+/-12 years were studied after a reperfused first MI.

63 (1 degree C) Euro-Collins solution and then reperfused for 1 hour at 37 degrees C were studied for e

64 cardioplegia for 4 hours at 4 degrees C, and reperfused for 1 hour.

65 n (UW) solution for 24 hr at 4 degrees C and reperfused for 1 hr at 37 degrees C in vitro.

66 d 40 hr (nonsurvival conditions) and ex vivo reperfused for 1 hr at 37 degrees C.

67 ck, transplanted into the recipient rat, and reperfused for 1 hr.

68 Hearts were reperfused for 120 minutes with unmodified perfusate (co

69 artery was then occluded for 60 minutes and reperfused for 120 minutes.

70 Afterward, kidneys were reperfused for 2 hr in an ex vivo model for assessment o

71 ed to 55 minutes prolonged warm ischemia and reperfused for 3 days (n = 6).

72 The artery was occluded for 30 min and reperfused for 3 h.

73 he mesenteric artery for 20 minutes and then reperfused for 3 hours.

74 e subjected to 35 min of global ischemia and reperfused for 30 min in the presence of incremental con

75 of global ischemia, isolated rat hearts were reperfused for 30 mins with Krebs-Henseleit solution alo

76 lly arrested for 4 hours at 4 degrees C, and reperfused for 30 minutes at 37 degrees C (postischemia

77 The hearts were reperfused for 30 minutes with KHB.

78 The hearts were reperfused for 30 minutes with Krebs-Henseleit buffer.

79 e retransplanted into ACI rat recipients and reperfused for 4 or 8 hours or 90 days (cyclosporine A 7

80 teric artery was occluded for 90 minutes and reperfused for 60 minutes.

81 rce transducer, ventilated with 100% O2, and reperfused for 90 min with fresh blood via a cannula in

82 ve cascade of inflammatory events within the reperfused graft vasculature is likely to be mediated, a

83 aled increased IL-1 mRNA within cells of the reperfused graft, including myocytes and endothelial cel

84 cation of each other's expression within the reperfused graft, promulgating inflammatory events that

85 cantly (p < 0.05) compared with non-iso/roli-reperfused groups after 2 h of postmortem ischemia.

86 The number of neutrophils in the reperfused heart at 24 hours after infarction correlated

87 In the isolated reperfused heart, phenylephrine, mediated by alpha-1 ago

88 In cardiac tissues obtained from ischemic/reperfused heart, significant Trx-1 nitration was detect

89 4+ T-cell accumulation and activation in the reperfused heart.

90 the activation of NF-kappaB in the ischemic-reperfused heart.

91 e of .OH similar to that which occurs in the reperfused heart.

92 a decrease in cardiomyocyte apoptosis in the reperfused heart.

93 s in the infarct boundary region of ischemia-reperfused heart.

94 increased in isoproterenol-treated ischemic/reperfused hearts in all mouse genotypes, but only in WT

95 ost left anterior descending artery occluded/reperfused hearts of Sh2b3(em2Mcwi) rats relative to wil

96 co-immunoprecipitated with GSTP, whereas in reperfused hearts, the association of AR with GRX was in

97 spectrofluorometry was increased in dopamine-reperfused hearts.

98 gher in the PC hearts compared with ischemic reperfused hearts.

99 ctivity similar to that seen in ischemic and reperfused hearts.

100 ppress complement activation and tested in a reperfused hemispheric stroke model in Papio anubis (bab

101 Reperfused ileum tissue sections from SAO-shocked rats s

102 iginally perfused in one mouse, could become reperfused in a secondary mouse.

103 d blood from an arrested animal but not when reperfused in saline.

104 In addition, isolated hearts reperfused in the presence of CORM-3 (10 micromol/L) aft

105 eperfused before contracture and to 56% when reperfused in the presence of HOE 694.

106 ored in University of Wisconsin Solution and reperfused in vitro to model renal tubule preservation i

107 ored in University of Wisconsin solution and reperfused in vitro to simulate renal cold storage prese

108 Regional myocardial blood flow in the reperfused infarct was reduced significantly compared wi

109 and to visualize its distribution pattern in reperfused infarcted myocardium as a function of time be

110 ) magnetic resonance (MR) contrast agents in reperfused infarcted myocardium, and 2) investigate the

111 -teboroxime uptake and clearance kinetics in reperfused infarcted myocardium.

112 rofosmin uptake was significantly reduced in reperfused, infarcted areas and was reflective of viabil

113 s significantly (P <.05) faster than that of reperfused infarction (0.99 sec(-1) +/- 0.03, 1.11 sec(-

114 ed in normal myocardium but was cleared from reperfused infarction and blood.

115 oss had accentuated adverse remodeling after reperfused infarction and exhibited an increased inciden

116 Forty-six rats were subjected to reperfused infarction and randomly divided into two grou

117 d distribution pattern of labeled albumin in reperfused infarction are modulated by duration of reper

118 After reperfused infarction IL-1RI-null mice exhibited decreas

119 ntensity in vivo measures infarct size after reperfused infarction in both a large and a small animal

120 P-10-null and wild-type (WT) mice undergoing reperfused infarction protocols and examined the effects

121 Mice undergoing reperfused infarction protocols were injected daily with

122 between young and senescent mice undergoing reperfused infarction protocols.

123 DTPA-albumin in blood, normal myocardium and reperfused infarction was dynamically measured with IR-E

124 l relaxation rate (R1) in normal myocardium, reperfused infarction, and blood was repeatedly measured

125 In reperfused infarction, however, the deltaR1-ratio increa

126 We used a canine and a murine model of reperfused infarction.

127 images and was clearly distinguishable from reperfused infarction.

128 lar as well as extracellular distribution in reperfused infarction.

129 y monitor myocardial microvascular injury in reperfused infarction.

130 nd cardiac remodeling using a mouse model of reperfused infarction.

131 On (Gd-DTPA)30-albumin-enhanced images, reperfused infarctions consisted of a bright border zone

132 c protein (MCP)-1 mRNA by cardiac venules in reperfused infarcts corresponded to the region where leu

133 enhanced magnetic resonance images of acute, reperfused infarcts have shown hypoenhanced and hyperenh

134 Twelve pigs with reperfused infarcts were studied with cardiovascular MR

135 111In anti-myosin delineated reperfused infarcts within 1 to 3 hours, but no uptake w

136 inducible nitric oxide synthase) within the reperfused intestinal graft muscularis.

137 o resulted in severe apoptotic damage to the reperfused intestinal mucosa.

138 ted the infiltration of neutrophils into the reperfused intestine (reduced MPO activity).

139 Infiltration of reperfused intestine allografts with CD14(+) macrophages

140 imaging inflammatory response in an ischemic-reperfused (IR) rat heart model.

141 chemic stroke mainly focus on new devices to reperfuse ischemic brain.

142 lected conduction disturbances, such as in a reperfused ischemic region surrounded by normal myocardi

143 (tPA) is the only FDA-approved treatment for reperfusing ischemic strokes.

144 transient venous release of sC5b-9 from the reperfused kidney graft in brain-dead donor and cardiac

145 local terminal complement activation in the reperfused kidney was assessed.

146 dynamic arteriovenous measurements over the reperfused kidney.

147 ced adherence of neutrophils to the ischemic-reperfused LAD coronary endothelium.

148 Moreover, vasorelaxation of ischemic-reperfused left anterior descending (LAD) coronary arter

149 an oxidant-generating enzyme), released from reperfusing liver and intestines, mediating a significan

150 ation without reperfusion or in unpreserved, reperfused livers.

151 perfusion were rapid, in ischemic tissue not reperfused, low levels of C/EBP were detected at 4 hours

152 effect was observed in anterior AMI patients reperfused <6 h of symptom onset.

153 In post-hoc analysis, anterior AMI patients reperfused <6 h who were treated with AO had a greater i

154 In patients who did not reperfuse (<10% reperfusion), baseline Tmax > 6-second l

155 Bronchoalveolar lavage of ischemic-reperfused lungs at 30 minutes and 4 hours of reperfusio

156 cumulation in the preserved and subsequently reperfused lungs correlated with the degree of preservat

157 s correlated with Kfc (r = 0.93) in iso/roli-reperfused lungs.

158 (5-LO) showed diminished PMN accumulation in reperfused lungs.

159 Twenty patients with a first reperfused MI (age, 53+/-12 years; 16 male; 11 inferior

160 infiltration was spatially inhomogeneous in reperfused MI areas.

161 ardial function to low-dose dobutamine after reperfused MI can be quantified with MR tagging.

162 its correlation to prognostic indicators of reperfused MI have not been well described.

163 Therapeutics, Inc., Baltimore, Maryland) in reperfused MI patients (n=53).

164 Monocyte recruitment was inhomogeneous in reperfused MI tissue.

165 In reperfused MI, microvascular integrity and contractile r

166 c function in intact mice early after large, reperfused MI, revealing the existence of contractile dy

167 ntary in assessing functional recovery after reperfused MI.

168 tment of monocytes in vivo in a rat model of reperfused MI.

169 mising new target for infarct salvage in non reperfused MI.

170 iac MR imaging 5 days or fewer after a first reperfused MI.

171 ction inflammatory response in patients with reperfused MI.

172 ) mice early (day 1) and late (day 28) after reperfused MI.

173 In reperfused mice, macrophage Mertk deficiency led to decr

174 bly improved washout of metabolites from the reperfused microcirculation in sites other than the smal

175 Much like the canine model, reperfused mouse hearts are associated with marked induc

176 Reperfused mouse infarcts show accelerated replacement o

177 nd PDGFR-beta mRNA expression was induced in reperfused mouse infarcts.

178 dy neutralization in a closed-chest model of reperfused murine myocardial infarction.

179 -energy phosphates and glutathione status in reperfused muscle (eg, preischemia groups: ATP, 30.23+/-

180 cardiac repair, and remodeling in mice after reperfused myocardial infarction (50-minute ischemia).

181 ascular integrity and contractile reserve of reperfused myocardial infarction (MI) in one examination

182 closporine A (CsA) has beneficial effects in reperfused myocardial infarction (MI) is debated.

183 as to noninvasively determine the effects of reperfused myocardial infarction (MI) on regional and gl

184 the extent of injury and inflammation in non reperfused myocardial infarction (MI).

185 n and left ventricular (LV) remodeling after reperfused myocardial infarction (MI).

186 atterns on contrast-enhanced MRI early after reperfused myocardial infarction (MI): (1) absence of no

187 for the early diagnosis of nonreperfused and reperfused myocardial infarction and compared with local

188 jected intramyocardially at 48 hours after a reperfused myocardial infarction in mice.

189 d corresponding wild-type controls underwent reperfused myocardial infarction protocols.

190 The remaining 6 rabbits with reperfused myocardial infarction were used for the asses

191 rent cytokine regimens, administered after a reperfused myocardial infarction, in regenerating cardia

192 Of 16 pigs subjected to reperfused myocardial infarction, six were treated, six

193 We conclude that in reperfused myocardial infarction, sodium accumulation is

194 R to delineate the area at risk 2 days after reperfused myocardial infarction.

195 etrospectively delineate the area at risk in reperfused myocardial infarction.

196 or just reperfusion flow in the setting of a reperfused myocardial infarction.

197 circumferential strain, in a swine model of reperfused myocardial infarction.

198 On Gd-DTPA-BMA-enhanced images, reperfused myocardial infarctions were homogeneously enh

199 dial hemorrhage frequently accompanies large reperfused myocardial infarctions.

200 e within minutes in persistently occluded or reperfused myocardial infarcts.

201 anges in myocardial contrast and function in reperfused myocardial injury.

202 ficant increase in NO production in ischemic/reperfused myocardial tissue.

203 and mRNA levels also increased in ischemic/ reperfused myocardial tissues.

204 ardiac catheterization laboratory to protect reperfused myocardium after primary angioplasty in patie

205 aluate the diastolic deformation of ischemic/reperfused myocardium and relate this deformation to tis

206 eries via release of adenosine from ischemic/reperfused myocardium and resultant adenosine receptor s

207 at lymphocytes infiltrating the ischemic and reperfused myocardium express IL-10 and may have a signi

208 Neutrophil transmigration into reperfused myocardium is more extensive than previously

209 edistribution of AIP 201 microbubbles to the reperfused myocardium is related to changes in MBF and o

210 In situ hybridization studies of reperfused myocardium localized IL-6 mRNA in infiltratin

211 The marked myocardial hyperoxygenation in reperfused myocardium may be a critical factor that trig

212 d functional abnormalities within completely reperfused myocardium recover in parallel.

213 nd NO and serves to protect the ischemic and reperfused myocardium through the suppression of neutrop

214 ion of P-selectin and ICAM-1 in ischemic and reperfused myocardium, and they also provide the basis f

215 h preservation of blood flow to the ischemic-reperfused myocardium, nor with any improvement in globa

216 is and neutrophil infiltration into ischemic-reperfused myocardium, which was mediated in part by P-s

217 f IL-10 mRNA and protein in the ischemic and reperfused myocardium.

218 e delayed PMN activation and accumulation in reperfused myocardium.

219 tly altered in mildly and moderately injured reperfused myocardium.

220 e inflammation and apoptosis in the ischemic-reperfused myocardium.

221 ole for MCP-1 in monocyte trafficking in the reperfused myocardium.

222 heme oxygenase were noticed in the ischemic reperfused myocardium.

223 MPIOs bound significantly to microthrombi in reperfused myocardium.

224 the contractile performance of the ischemic/reperfused myocardium.

225 ment-intact mice gave specific uptake in the reperfused myocardium.

226 a direct cardioprotective effect on ischemic/reperfused myocardium.

227 After preservation kidneys were reperfused on an ex vivo perfusion system for 3 hr with

228 Of these allografts, three reperfused once repositioned and six were successfully t

229 Cardiac function was assessed after reperfused or nonreperfused infarction using echocardiog

230 ization (r = .60 for nonreperfused; 0.76 for reperfused; P < .0001) was observed.

231 canalized PAVMs but only 44% (n = 4) of nine reperfused PAVMs.

232 significantly differ between recanalized and reperfused PAVMs.

233 Reperfused pigs had significantly higher myocardial wate

234 When cold stored livers were reperfused, PSGL-1 reduced the degree of hepatocyte tran

235 ) levels correlated with Kfc in non-iso/roli-reperfused (r = 0.89) and iso/roli-reperfused (r = 0.97)

236 -iso/roli-reperfused (r = 0.89) and iso/roli-reperfused (r = 0.97) lungs.

237 rotective potential of erythropoietin in the reperfused rabbit heart following ventricular ischemia.

238 enhanced magnetic resonance images of acute, reperfused rabbit infarcts, differential image intensity

239 onduction and contraction is described in 25 reperfused rabbit papillary muscles.

240 ine the cellular localization of the MMPs in reperfused rat brain, and cell cultures to study their a

241 IPA) on amino acid release from the ischemic/reperfused rat cerebral cortex was investigated using a

242 including arachidonic acid, in the ischemic/reperfused rat cerebral cortex, using a cortical cup tec

243 mate and aspartate release from the ischemic/reperfused rat cerebral cortex.

244 The ischemic-reperfused rat heart models were created by ligating the

245 ocardial contractile dysfunction of ischemic-reperfused rat hearts to near baseline levels, and marke

246 ogenous Ucn reduces infarct size in ischemic-reperfused rat hearts.

247 lease may contribute to DNA fragmentation in reperfused rat kidneys.

248 on after ischemia, neutrophil recruitment to reperfused rat myocardium is mainly due to cardiomyocyte

249 rupts the development of oxidative stress in reperfused rat-heart allografts.

250 stolic wall thickening (WTh) in the ischemic-reperfused region on day 1 remained significantly depres

251 stolic wall thickening (WTh) in the ischemic/reperfused region remained significantly depressed for 4

252 stolic wall thickening (WTh) in the ischemic/reperfused region remained significantly depressed for a

253 ant 3D diastolic dysfunction in the ischemic-reperfused region transmurally.

254 Reperfused regions had largely inactive glycogen synthas

255 When examined at 24 hours, reperfused regions were fully contractile and viable by

256 Infarcted, reperfused regions, identified by triphenyltetrazolium c

257 aging were conducted in 32 rats subjected to reperfused reversible (n = 16) and irreversible (n = 16)

258 eir clinical benefit, the failure to rapidly reperfuse some patients and the persistent bleeding risk

259 In 186 patients, reperfused ST segment elevation MI myocardial infarction

260 omized 200 patients with large, successfully reperfused ST-segment elevation myocardial infarction in

261 a prospective cohort study in patients with reperfused ST-segment-elevation MI who underwent cardiac

262 ion tomography and magnetic resonance in the reperfused ST-segment-elevation myocardial infarction pa

263 gets for preventing adverse LV remodeling in reperfused ST-segment-elevation myocardial infarction pa

264 s has not been investigated in patients with reperfused ST-segment-elevation myocardial infarction.

265 mized, controlled, proof-of-concept trial in reperfused STEMI patients with >/=1 risk factors for no-

266 nd recurrent angina compared with UFH in non-reperfused STEMI patients.

267 nt predictor of clinical outcome after acute reperfused STEMI.

268 vage index, and delayed enhancement in acute reperfused STEMI.

269 uced infarct size and edema in patients with reperfused STEMI.

270 odel that may more closely approximate human reperfused stroke.

271 eversibly injured myocardium associated with reperfused subendocardial infarctions.

272 implantation, unseeded scaffolds were easily reperfused, sustained blood pressure, and were tolerated

273 atheter-based interventions may successfully reperfuse the limbs of certain patients with peripheral

274 lantation (OLT), it is standard procedure to reperfuse the liver via the portal vein (PV) despite hav

275 and necessitated vascular reconstruction to reperfuse the lower extremity.

276 GTPase Rac1 mediates the oxidative burst in reperfused tissue and thereby contributes to reperfusion

277 The sources of reactive oxygen species in reperfused tissue are not fully characterized.

278 Selenide targets to reperfusing tissue and reduces reperfusion injury perhap

279 gut ischemia, resulting in further injury to reperfused tissues and distant injury to lungs and other

280 10 enhanced neutrophil infiltration into the reperfused tissues at 6 hours after reperfusion and incr

281 s neutrophil migration and accumulation into reperfused tissues, thereby ameliorating the outcome of

282 minutes of ischemia, the left ventricle was reperfused to allow blood flow through the previously oc

283 ome reperfusion already at admission or were reperfused too late to expect any myocardial salvage.

284 thelial cells (LSECs) are repopulated in the reperfused transplanted liver after 18 hours of cold isc

285 th livers perfused at lower oxygen tensions, reperfused uneventfully.

286 gone OLT with HA reperfusion and 26 patients reperfused via the PV.

287 Perfusion hearts were reperfused with a protective solution then perfused for

288 Another group of 24-hr preserved livers were reperfused with cold hypoxic buffer to differentiate the

289 The lungs were reperfused with Earle's solution with or without a combi

290 -hour simple cold storage (SCS), livers were reperfused with Krebs-Henseleit buffer solution at 37 de

291 C UW and Plegisol for 3 and 6 hours and then reperfused with normal buffer.

292 The kidneys were reperfused with oxygenated autologous blood for 3 hr on

293 ve recovery in patients who are successfully reperfused with primary angioplasty (PTCA) for acute myo

294 of 36 torr, pH 7.4), and compared with cells reperfused with relative hypercarbia (PCO2 of 71 torr, p

295 ed from non-heart-beating donors (NHBDs) and reperfused with the addition of the beta(2)-adrenergic r

296 Following ischemia, the hearts were reperfused with the K2RBC perfusate.

297 ity of Wisconsin solution, transplanted, and reperfused without immunosuppression for 7 days (n = 5).

298 Interestingly, coronary flow reserve in the reperfused zone of group 1 was diminished despite the ab

299 connexin-43 phosphorylation recovered in the reperfused zone, CV normalized, and arrhythmias resolved

300 .0 +/- 3.0 minutes, promoting reentry in the reperfused zone.