ライフサイエンスコーパス: repetitive sequence

1 ered two surprising patterns of evolution in repetitive sequence.

2 onsidered 'untilable' due to the presence of repetitive sequence.

3 pping over a template base that is part of a repetitive sequence.

4 at genomes consist of previously unannotated repetitive sequence.

5 mber variation of paralogous genes, and long repetitive sequences.

6 cal properties can function cooperatively at repetitive sequences.

7 may provide new insight to the evolution of repetitive sequences.

8 ric deletions and large insertions of middle repetitive sequences.

9 y of the neuron, partly mediated by co-opted repetitive sequences.

10 ly been shown to regulate CpG methylation at repetitive sequences.

11 target loci, including transposons and other repetitive sequences.

12 -chimpanzee divergence vary around different repetitive sequences.

13 ribosomal DNA, and a number of unclassified repetitive sequences.

14 ssion and in silencing transposons and other repetitive sequences.

15 ts largely of transposon-enriched and highly repetitive sequences.

16 om transposable elements and their remnants, repetitive sequences.

17 region, which is largely composed of highly repetitive sequences.

18 group tended to associate with Alu and other repetitive sequences.

19 ain eukaryotic genomes that contain abundant repetitive sequences.

20 enetic elements such as retrotransposons and repetitive sequences.

21 parently non-repetitive and fewer matches to repetitive sequences.

22 common in different regions of Alu and other repetitive sequences.

23 on of TALEs remains challenging due to their repetitive sequences.

24 ate than Pol epsilon for deletions involving repetitive sequences.

25 nce tag-derived simple sequence repeats, and repetitive sequences.

26 map to genomic regions containing conserved repetitive sequences.

27 nts represent genomic segments lying between repetitive sequences.

28 ences showed significant similarity to maize repetitive sequences.

29 ation over acetylation (Me/Ac), 13 contained repetitive sequences.

30 to duplication, deletion, and divergence of repetitive sequences.

31 metazoan parasites, is predicted to comprise repetitive sequences.

32 4 (H3-K4me) at pericentromeric DNA and other repetitive sequences.

33 tent, target footprint size and spacing, and repetitive sequences.

34 nce methylation by Dnmt1 of these endogenous repetitive sequences.

35 errors caused by DNA polymerase slippage at repetitive sequences.

36 by gene-poor blocks of retrotransposon-like repetitive sequences.

37 ions and deletions in non-iterated and short repetitive sequences.

38 ively bind and enrich hypervariable, long or repetitive sequences.

39 in Rb1 that is defective for recruitment to repetitive sequences.

40 rate and capable of recovering most types of repetitive sequences.

41 ts hugely increase indel mutagenesis in long repetitive sequences.

42 ntaining transposons, pseudogenes, and other repetitive sequences.

43 ed in upregulation of two genes and multiple repetitive sequences.

44 species, namely with and without centromeric repetitive sequences.

45 als, particularly at heterochromatin-located repetitive sequences.

46 bases long and from regions with short or no repetitive sequences.

47 east and mammalian CTD are hampered by their repetitive sequences.

48 ns at chicken centromeres, which lack highly repetitive sequences.

49 ut lack the added complication of underlying repetitive sequences.

50 the ordered, recombination-based assembly of repetitive sequences.

51 the issues caused by genome duplication and repetitive sequences.

52 l RNA polymerase II after the synthesis of a repetitive sequence (5'-CUCUCU-3') at varying distances

53 s that tends to increase the variation among repetitive sequences, a chromosome-specific substructuri

54 Because of alternative splicing and repetitive sequences, a ribosome-protected read may map

55 nces with FISH probes by considering locally repetitive sequences absent from the remainder of the ge

56 Repetitive sequences account for approximately half of t

57 Repetitive sequences accounted for 46.1% of the assemble

58 ific sequences in subfamilies of ERVL and L1 repetitive sequences, accounting for an additional 17.9%

59 We propose that amplified repetitive sequences act as selfish elements by promotin

60 that as part of the expansion process, these repetitive sequences adopt non-B conformations such as h

61 dition to Hyp by building genes encoding the repetitive sequences (alanine [Ala]-proline [Pro]-Ala-Pr

62 the D. pseudoobscura genome are flanked by a repetitive sequence also found at the breakpoints of chr

63 t for single-stranded DNA (ssDNA) having non-repetitive sequences and 40-80% GC.

64 Large repetitive sequences and complex allelic diversity are t

65 at regulate persistence of hairpins in these repetitive sequences and conversion to canonical duplex.

66 iverse arrangements of chromosomal segments, repetitive sequences and distribution of genes.

67 hondrion (459,678 nt) with relatively little repetitive sequences and DNA of plastid origin.

68 al primary structure of C-hordein has highly repetitive sequences and forms a secondary structure of

69 mosome genetic degeneration, accumulation of repetitive sequences and heteromorphism.

70 We characterize several types of simple repetitive sequences and low-complexity regions that are

71 LncRNAs are rich in repetitive sequences and preferentially expressed in a t

72 TEnest identifies repetitive sequences and reconstructs separated sections

73 The nature of their repetitive sequences and the almost identical structures

74 cripts, including derepression of non-coding repetitive sequences and their neighboring protein encod

75 or predict the positions of coding regions, repetitive sequences and transcription factor binding si

76 f Cen8 genes, even when embedded in a sea of repetitive sequences and transposable elements.

77 ly one-third of the human genome consists of repetitive sequences, and DSB repair by HR often require

78 Heterochromatin is highly enriched for repetitive sequences, and is defined epigenetically by m

79 HPL-2 binding is enriched for repetitive sequences, and on chromosome arms is anticorr

80 e find that pericentromeric heterochromatin, repetitive sequences, and regions producing small interf

81 DNA double strand breaks (DSBs) in repetitive sequences are a potent source of genomic inst

82 iotic recombination map and intrachromosomal repetitive sequences are abundant.

83 As repetitive sequences are believed to facilitate spreadin

84 Repetitive sequences are biologically and clinically imp

85 ions generated by a fast replacement rate of repetitive sequences are buffered by the polyploid natur

86 Short repetitive sequences are common in the human genome, and

87 Repetitive sequences are especially at risk during meios

88 Because repetitive sequences are not uniformly distributed among

89 Transposable elements (TEs) and repetitive sequences are ubiquitously present in eukaryo

90 Matches to repetitive sequences are usually undesirable in the outp

91 his study thus identifies RNA:RNA pairing by repetitive sequences as a novel form of alternative spli

92 eling strategy is very powerful in targeting repetitive sequences as well as in barcoding genomic reg

93 ippage mechanism to generate -1 deletions in repetitive sequences, as do the bacterial and archaeal h

94 LH3 together with MSH2-MSH3 and localizes to repetitive sequences at centromeres and the Y chromosome

95 imately half of the human genome consists of repetitive sequence attributed to the activities of mobi

96 sing primers specific for mouse interspersed repetitive sequences (B1 elements).

97 Repetitive sequence-based PCR (rep-PCR) and amplified fr

98 Repetitive sequence-based PCR (REP-PCR) and serologic an

99 The system utilizes automated repetitive sequence-based PCR (rep-PCR) and web-based da

100 detection of antibiotic resistance genes and repetitive sequence-based PCR (rep-PCR) assessments of c

101 g and analysis, is an automated method using repetitive sequence-based PCR (rep-PCR) for microbial st

102 Repetitive sequence-based PCR (rep-PCR) has been recogni

103 Repetitive sequence-based PCR (rep-PCR) showed minimal p

104 Clonality was assessed by repetitive sequence-based PCR (repPCR) and multilocus se

105 Repetitive sequence-based PCR and dendrogram analysis we

106 Fingerprinting of 16 isolates by repetitive sequence-based PCR showed that all were diffe

107 e typed by pulsed-field gel electrophoresis, repetitive sequence-based PCR typing, and rapid multiloc

108 olates was then subjected to high-resolution repetitive sequence-based PCR typing, which identified 1

109 Repetitive sequence-based PCR was found to be a technica

110 gularity extraction has focused primarily on repetitive sequence-based rules within the sensory envir

111 PCR-sequencing of bla genes, immunoblotting, repetitive-sequence-based PCR (rep-PCR) and multilocus s

112 Strain relatedness was assessed by repetitive-sequence-based PCR (rep-PCR) and pulsed-field

113 A commercially available repetitive-sequence-based PCR (rep-PCR) DNA fingerprinti

114 Repetitive-sequence-based PCR (rep-PCR) is useful for ge

115 Repetitive-sequence-based PCR (rep-PCR) using the Divers

116 The performance of repetitive-sequence-based PCR (rep-PCR) using the Divers

117 obacterial interspersed repetitive units and repetitive-sequence-based PCR (rep-PCR).

118 loid and the amplification and dispersion of repetitive sequences best explain the large genome size

119 complexity proteins; they are organized into repetitive sequence blocks and found to maintain homolog

120 hanism of repeat gain is dependent on highly repetitive sequence but, surprisingly, is independent of

121 . betularia W chromosome consists largely of repetitive sequence, but exceptionally we found a W homo

122 olkappa creates single-base deletions in non-repetitive sequences, but does not address how deletions

123 In addition to repetitive sequences, C(o)t-1 was found to be enriched f

124 Telomeric DNA usually consists of a repetitive sequence: C(1-3)A/TG(1-3) in yeast, and C(3)T

125 a powerful means by which both low-copy and repetitive sequences can be selectively and efficiently

126 Centromeres and other repetitive sequences can drive in meiosis by cheating th

127 tial emergence of heterochromatin on various repetitive sequences changes their replication order and

128 n the temperature at which the most abundant repetitive sequence classes anneal and habitat thermal s

129 We find notable heterogeneity in repetitive sequence composition among the sequenced geno

130 vation along the chromosome, we compared the repetitive sequence composition of this region between t

131 These repetitive sequences contain consensus DNA-binding sites

132 s uniform gene density over chromosomes, low repetitive sequence content ( approximately 6%), and a h

133 o share genic features, they differ in their repetitive sequence content and composition suggesting t

134 lit between two subgenomes, with significant repetitive sequence content limiting the efficiency of r

135 papaya X; expansion is supported by a higher repetitive sequence content of the X compared with the p

136 genomes due to the large genome sizes, high repetitive sequence content, and rampant whole- or segme

137 he genuine leptin gene with a GC-rich ( 70%) repetitive-sequence content was identified in the chicke

138 nguished from tissue-specific genes by their repetitive sequence context.

139 that formation of non-B conformations by the repetitive sequence contributes to the expansion mechani

140 istical correlations there is a tendency for repetitive sequence density to be negatively correlated

141 Repetitive sequences derived from transposons make up a

142 ts fibronection and plasminogen by virtue of repetitive sequences-designated streptococcal surface re

143 tDNAs are repetitive sequences dispersed throughout the human geno

144 These trends in repetitive sequence distribution are strongly correlated

145 anding the different levels of segmental and repetitive sequence duplication and distribution of gene

146 We found multiple copies of a repetitive sequence element termed RSR in genomes of spe

147 2 Mb due to a more accurate determination of repetitive sequence elements and assembled the complete

148 x1 to account for NOH-1S formation, we found repetitive sequence elements bordering the deleted regio

149 The fission yeast pericentromere comprises repetitive sequence elements packaged into heterchromati

150 a hypermutable region because of surrounding repetitive sequence elements that may catalyze the forma

151 heds new light on functional roles for short repetitive sequences embedded deep within introns throug

152 culties in sequencing through and assembling repetitive sequences enriched in the heterochromatin.

153 ng genes from tissue-specific genes and that repetitive sequence environment distinguishes housekeepi

154 as a measure of success, we demonstrate that repetitive sequence environment is by far the most impor

155 The distinct repetitive sequence environment, in combination with oth

156 -base deletion errors at high frequencies in repetitive sequences, especially those that contain two

157 es (IESs), many of which belong to dispersed repetitive sequence families.

158 The PE-PGRS (Pro-Glu polymorphic GC-rich repetitive sequence) family of genes, which are unique t

159 of small CRISPR RNAs (crRNAs) consisting of repetitive sequences flanking unique spacers to recogniz

160 Repetitive sequences follow a nonspecific pathway to ren

161 such sequences, we constructed databases of repetitive sequences for 12 plant genera: Arabidopsis, B

162 d vector adjacent to the host DNA, utilizing repetitive sequences for homologous recombination to pro

163 Among several different types of repetitive sequences found in the human genome, this stu

164 DNA methylation is essential for protecting repetitive sequences from aberrant transcription and rec

165 The ASGR includes highly repetitive sequences from an Opie-2-like retrotransposon

166 echanisms causes their insertions into other repetitive sequences, gene loci and other DNA.

167 ations result from strand slippage, which in repetitive sequences generates misaligned intermediates

168 EccDNA arose both from genomic regions with repetitive sequences >/= 15 bases long and from regions

169 of where to put a metal site along a linear, repetitive sequence has not been thoroughly addressed.

170 ences in other genera within these families, repetitive sequences have been combined into four databa

171 because alterations in these highly mutable repetitive sequences have been linked with many phenotyp

172 Since repetitive sequences have been reported to influence the

173 bably supported by an atypical complement of repetitive sequence in the genome.

174 Here, we describe another repetitive sequence in the human genome, the SVA element

175 n N-terminal catalytic domain and noncomplex repetitive sequence in the remainder of the molecule.

176 ted the role of genetic variation within the repetitive sequence in the transcriptional control regio

177 on 'slippage' events both create and destroy repetitive sequences in bacterial genomes.

178 and template-switching at the site of short repetitive sequences in DNA.

179 ut sequencing shows that Khd1 directly binds repetitive sequences in FLO11 mRNA.

180 volvement of transposable elements and other repetitive sequences in genome restructuring and gene re

181 Cross-hybridization of repetitive sequences in genomic and expression arrays is

182 nk." Yet, persistence of these tandem highly repetitive sequences in heterochromatic regions of most

183 pecific and orthogonal two-color labeling of repetitive sequences in living human cells using this me

184 ents (TEs) contribute to the large amount of repetitive sequences in mammalian genomes and have been

185 and to provide a resource for searching for repetitive sequences in other genera within these famili

186 To better understand the nature of repetitive sequences in plants and provide a resource fo

187 entification, classification and analysis of repetitive sequences in plants.

188 Parallel analyses of repetitive sequences in potato and tomato revealed subst

189 f our genome, revealing a prominent role for repetitive sequences in shaping its structural variation

190 cation of specific regions between noncoding repetitive sequences in the bacterial genome.

191 The repetitive sequences in the coding regions primarily rep

192 (MSI) refers to the hypermutability of short repetitive sequences in the genome caused by impaired DN

193 er of Ac transposition events were to highly repetitive sequences in the genome.

194 some positioning motifs and the densities of repetitive sequences in the human genome.

195 rence genome due to sequencing errors and/or repetitive sequences in the reference.

196 h displayed different organization of highly repetitive sequences in the two genomes.

197 ed adhesins and virulence factors exhibiting repetitive sequences in their core structure.

198 ficant differences were identified in highly repetitive sequences, including centromere, 45S ribosoma

199 methylation in tumors occurs specifically at repetitive sequences, including short and long intersper

200 Approximately 76% of the region contained repetitive sequences, including transposon-like sequence

201 opy number estimates including all dispersed repetitive sequences indicate that 40%-65% of each genom

202 abundance short interfering RNAs that match repetitive sequences, intergenic regions and genes.

203 e small interfering RNAs (siRNAs) that match repetitive sequences, intergenic regions, and genes.

204 We also identify 1.3 Mb of non-repetitive sequence interspersed with HSat2,3 across 17

205 ely 80% of the maize genome comprises highly repetitive sequences interspersed with single-copy, gene

206 A repetitive sequence is found in the D. pseudoobscura gen

207 Instability of repetitive sequences is a hallmark of human cancer, and

208 PCR amplification over GC-rich and/or long repetitive sequences is challenging because of thermo-st

209 Moreover, we show that this core of repetitive sequences is expressed throughout the nucleus

210 epair efficiencies of DNA damage within such repetitive sequences is therefore crucial for understand

211 whole-genome assembly due to an abundance of repetitive sequence, leading to the development of gene-

212 m analysis with a highly polymorphic GC-rich repetitive sequence located in the plasmid pTBN12 (PGRS

213 f ICF patients, including hypomethylation of repetitive sequences, low body weight, distinct cranial

214 f human non-protein-coding DNA is made up of repetitive sequences, mainly transposable elements (TEs)

215 Repetitive sequences make up a major part of eukaryotic

216 Repetitive sequences make up a significant fraction of a

217 ence content and composition suggesting that repetitive sequences may have a more significant role in

218 c RNA, but also demonstrate that ligands for repetitive sequences may have unexpected effects on RNA

219 a suggest that transcription of interspersed repetitive sequences may represent a developmental strat

220 hey suggest that the residues flanking these repetitive sequences may represent viable therapeutic ta

221 rosophila cells, dsRNAs corresponding to non-repetitive sequences mediated a high degree of sequence-

222 Genes composed of tandem repetitive sequence motifs are abundant in nature and ar

223 malignancies that is distinguished by highly repetitive sequences ("mucin repeats") in the extracellu

224 p to 13 Mbp) and smaller hotspots flanked by repetitive sequence (n = 1,247, median size 79 kbp, rang

225 ncluding the constitutive heterochromatin on repetitive sequences near centromeres and telomeres, nee

226 Repetitive sequences need not be matched to a query, if

227 bonuclease Csy4, which binds and cleaves the repetitive sequence of the CRISPR transcript.

228 ed-coil domain and associates densely on the repetitive sequence of the phosphorylated CTD via its N-

229 abolition of NFC101/NFC102 association with repetitive sequences of different transposable elements

230 Despite the GC-rich, highly repetitive sequences of ELPs, we synthesized remarkably

231 molecules and integrate them in between the repetitive sequences of the CRISPR array in the form of

232 oligonucleotide arrays that tile all the non-repetitive sequences of the human genome at 35 bp resolu

233 Telomeres are repetitive sequences of variable length at the ends of c

234 rge and complex genomes containing extensive repetitive sequences, of which the bulbous and monocotyl

235 s on whether the genomic context is tandemly repetitive sequences often found near centromeres, which

236 ecombination is more likely to occur between repetitive sequences on nonhomologous chromosomes.

237 Thus, dynamic DNA methylation changes within repetitive sequences or transposons can regulate neighbo

238 unusual amino acid composition and extensive repetitive sequence organised into two defined repeat re

239 Close to 50% of the human genome harbors repetitive sequences originally derived from mobile DNA

240 c elements (MGEs) will make up much of these repetitive sequences, particularly the interspersed sequ

241 nce and mutator status and were genotyped by repetitive-sequence PCR (rep-PCR), pulsed-field gel elec

242 We performed a blinded study to compare repetitive-sequence PCR and multilocus sequence typing f

243 n, and the CTV-05 strain was discerned using repetitive-sequence polymerase chain reaction DNA finger

244 typing of S aureus strains was performed by repetitive-sequence polymerase chain reaction to determi

245 on and errors in the human reference genome, repetitive sequences, polymorphisms, variable sample qua

246 However, the presence of tandem repetitive sequences prevents pre-assembly of long reads

247 he proline glutamic acid-polymorphic GC-rich repetitive sequences protein family of M. tuberculosis.

248 To examine the stability of repetitive-sequence (rep) PCR profiles, six species of b

249 keeping genes while various longer (>400-bp) repetitive sequences ("repeats"), including Long Intersp

250 Thus, our study reveals a potential shift in repetitive sequence representation between these extreme

251 themselves consist largely of 125 and 102 bp repetitive sequences, respectively, and encode basic pro

252 se two species including a telomeric-related repetitive sequence, ribosomal DNA, and a number of uncl

253 ns a prion-forming domain characterized by a repetitive sequence rich in Gln, Asn, Tyr, and Gly amino

254 f the maize (Zea mays L.) genome consists of repetitive sequences, sequencing efforts are being targe

255 f its disordered, atypically hydrophilic and repetitive sequence signatures.

256 otably, with sgRNAs targeted to standard non-repetitive sequences, SpCas9-HF1 rendered all or nearly

257 s showed that this BAC consists primarily of repetitive sequences such as a 102-bp tandem repeat with

258 Repetitive sequences such as transposable elements trigg

259 nism for silencing transgenes and endogenous repetitive sequences such as transposons.

260 the human and mouse genomes are comprised of repetitive sequences, such as transposable elements (TEs

261 polymerase eta, decreased 10-fold before the repetitive sequence, suggesting that the polymerase was

262 on, a similar examination of other genes and repetitive sequences suggests the non-random distributio

263 in the rat medial prefrontal cortex during a repetitive sequence task were preserved during subsequen

264 Genome features, such as repetitive sequences, telomeres, conserved syntenic bloc

265 Selected repetitive sequences termed short inverted repeats (SIRs

266 n effect on 241 methylated loci and selected repetitive sequences than that of the single treatment.

267 smaller size are more capable of recovering repetitive sequences than those of bigger size.

268 age occurs when an RNA transcript contains a repetitive sequence that allows the transcript to slip b

269 density in DNA flanking both sides of a 1-kb repetitive sequence that forms the core of the switch re

270 Spider silk genes are composed mostly of repetitive sequence that is flanked by non-repetitive te

271 The genome is burdened with repetitive sequences that are generally embedded in sile

272 Telomeres are composed of repetitive sequences that can be maintained by telomeras

273 Replication slippage is induced at repetitive sequences that can be very small and tend to

274 tantial portion of the genome is composed of repetitive sequences that can hinder genome annotation a

275 to uncover mapped genomic sites from highly repetitive sequences that can not be detected based on u

276 The genome has ~25% repetitive sequences that have been affected by repeat-i

277 ntronic DNA or in the distribution of middle repetitive sequences that have teleregulatory impact.

278 nomes harbor transposable elements and other repetitive sequences that must be silenced.

279 lex eukaryotic genomes, consisting of highly repetitive sequences that resist mapping, cloning and se

280 m and P. vivax to identify species-specific, repetitive sequences that serve as new PCR targets for t

281 DNA elimination reveals that in all species, repetitive sequences (that differ among the genera) and

282 n ancestor of the Brassica and, unlike other repetitive sequences, there is no evidence for genome-wi

283 We developed a model telomere lacking repetitive sequences to study the distribution of HipHop

284 onsistent with the idea that the presence of repetitive sequences upstream of the enhancer in the LTR

285 ped developmental program in which different repetitive sequences use distinct interactions and indep

286 n intergenic regions consisting primarily of repetitive sequences vary substantially along the loci a

287 he human genome, and mutation rates of these repetitive sequences vary with respect to DNA sequence a

288 sites of long interspersed nuclear element-1 repetitive sequences was assessed in a group of 63 patie

289 ere sequenced, annotated and the presence of repetitive sequences was determined.

290 On non-repetitive sequences, we find that nucleotide misincorpo

291 ciated changes in chromatin accessibility at repetitive sequences, we suggest that replication gaps r

292 Specific classes and types of repetitive sequences were also differentially represente

293 Very few repetitive sequences were detected, and the process of r

294 site resulted in homologous recombination of repetitive sequences, which is required for gene silenci

295 The first capture depletes the library of repetitive sequences, while the second enriches for targ

296 In the course of a search for any type of repetitive sequences whose copy numbers have substantial

297 Rs belong to a broader group of weak-folding repetitive sequences with potential regulatory roles.

298 Here, multiple frameshifts are identified in repetitive sequences within an Epstein-Barr virus unspli

299 The repetitive sequences within each database have been code

300 Finally we describe a novel repetitive sequence, wtf, which was also preferentially