ライフサイエンスコーパス: repetitive sequence

1 annotations (e.g., transposable elements and repetitive sequences).

2 ered two surprising patterns of evolution in repetitive sequence.

3 onsidered 'untilable' due to the presence of repetitive sequence.

4 pping over a template base that is part of a repetitive sequence.

5 at genomes consist of previously unannotated repetitive sequence.

6 to failure when their genetic parts contain repetitive sequences.

7 the ordered, recombination-based assembly of repetitive sequences.

8 the issues caused by genome duplication and repetitive sequences.

9 cal properties can function cooperatively at repetitive sequences.

10 may provide new insight to the evolution of repetitive sequences.

11 y of the neuron, partly mediated by co-opted repetitive sequences.

12 ly been shown to regulate CpG methylation at repetitive sequences.

13 target loci, including transposons and other repetitive sequences.

14 -chimpanzee divergence vary around different repetitive sequences.

15 ribosomal DNA, and a number of unclassified repetitive sequences.

16 ssion and in silencing transposons and other repetitive sequences.

17 ts largely of transposon-enriched and highly repetitive sequences.

18 om transposable elements and their remnants, repetitive sequences.

19 region, which is largely composed of highly repetitive sequences.

20 group tended to associate with Alu and other repetitive sequences.

21 ain eukaryotic genomes that contain abundant repetitive sequences.

22 enetic elements such as retrotransposons and repetitive sequences.

23 parently non-repetitive and fewer matches to repetitive sequences.

24 common in different regions of Alu and other repetitive sequences.

25 ate than Pol epsilon for deletions involving repetitive sequences.

26 nce tag-derived simple sequence repeats, and repetitive sequences.

27 map to genomic regions containing conserved repetitive sequences.

28 nts represent genomic segments lying between repetitive sequences.

29 mber variation of paralogous genes, and long repetitive sequences.

30 ences showed significant similarity to maize repetitive sequences.

31 ation over acetylation (Me/Ac), 13 contained repetitive sequences.

32 to duplication, deletion, and divergence of repetitive sequences.

33 metazoan parasites, is predicted to comprise repetitive sequences.

34 ively bind and enrich hypervariable, long or repetitive sequences.

35 east and mammalian CTD are hampered by their repetitive sequences.

36 ric deletions and large insertions of middle repetitive sequences.

37 on of TALEs remains challenging due to their repetitive sequences.

38 tent, target footprint size and spacing, and repetitive sequences.

39 in Rb1 that is defective for recruitment to repetitive sequences.

40 rate and capable of recovering most types of repetitive sequences.

41 % of mouse and human genomes are composed of repetitive sequences.

42 ts hugely increase indel mutagenesis in long repetitive sequences.

43 ntaining transposons, pseudogenes, and other repetitive sequences.

44 ed in upregulation of two genes and multiple repetitive sequences.

45 species, namely with and without centromeric repetitive sequences.

46 als, particularly at heterochromatin-located repetitive sequences.

47 bases long and from regions with short or no repetitive sequences.

48 ns at chicken centromeres, which lack highly repetitive sequences.

49 ut lack the added complication of underlying repetitive sequences.

50 l RNA polymerase II after the synthesis of a repetitive sequence (5'-CUCUCU-3') at varying distances

51 s that tends to increase the variation among repetitive sequences, a chromosome-specific substructuri

52 Because of alternative splicing and repetitive sequences, a ribosome-protected read may map

53 nces with FISH probes by considering locally repetitive sequences absent from the remainder of the ge

54 Repetitive sequences account for approximately half of t

55 Repetitive sequences accounted for 46.1% of the assemble

56 ific sequences in subfamilies of ERVL and L1 repetitive sequences, accounting for an additional 17.9%

57 We propose that amplified repetitive sequences act as selfish elements by promotin

58 that as part of the expansion process, these repetitive sequences adopt non-B conformations such as h

59 dition to Hyp by building genes encoding the repetitive sequences (alanine [Ala]-proline [Pro]-Ala-Pr

60 the D. pseudoobscura genome are flanked by a repetitive sequence also found at the breakpoints of chr

61 t for single-stranded DNA (ssDNA) having non-repetitive sequences and 40-80% GC.

62 Large repetitive sequences and complex allelic diversity are t

63 at regulate persistence of hairpins in these repetitive sequences and conversion to canonical duplex.

64 hondrion (459,678 nt) with relatively little repetitive sequences and DNA of plastid origin.

65 al primary structure of C-hordein has highly repetitive sequences and forms a secondary structure of

66 mosome genetic degeneration, accumulation of repetitive sequences and heteromorphism.

67 LncRNAs are rich in repetitive sequences and preferentially expressed in a t

68 TEnest identifies repetitive sequences and reconstructs separated sections

69 The nature of their repetitive sequences and the almost identical structures

70 cripts, including derepression of non-coding repetitive sequences and their neighboring protein encod

71 f Cen8 genes, even when embedded in a sea of repetitive sequences and transposable elements.

72 ly one-third of the human genome consists of repetitive sequences, and DSB repair by HR often require

73 Heterochromatin is highly enriched for repetitive sequences, and is defined epigenetically by m

74 HPL-2 binding is enriched for repetitive sequences, and on chromosome arms is anticorr

75 e find that pericentromeric heterochromatin, repetitive sequences, and regions producing small interf

76 DNA double strand breaks (DSBs) in repetitive sequences are a potent source of genomic inst

77 As repetitive sequences are believed to facilitate spreadin

78 Repetitive sequences are biologically and clinically imp

79 ions generated by a fast replacement rate of repetitive sequences are buffered by the polyploid natur

80 Short repetitive sequences are common in the human genome, and

81 Although repetitive sequences are enriched in H3K9me2 and linker

82 Repetitive sequences are especially at risk during meios

83 Repetitive sequences are hotspots of evolution at multip

84 Because repetitive sequences are not uniformly distributed among

85 Transposable elements (TEs) and repetitive sequences are ubiquitously present in eukaryo

86 Matches to repetitive sequences are usually undesirable in the outp

87 his study thus identifies RNA:RNA pairing by repetitive sequences as a novel form of alternative spli

88 eling strategy is very powerful in targeting repetitive sequences as well as in barcoding genomic reg

89 ippage mechanism to generate -1 deletions in repetitive sequences, as do the bacterial and archaeal h

90 LH3 together with MSH2-MSH3 and localizes to repetitive sequences at centromeres and the Y chromosome

91 imately half of the human genome consists of repetitive sequence attributed to the activities of mobi

92 sing primers specific for mouse interspersed repetitive sequences (B1 elements).

93 Repetitive sequence-based PCR (REP-PCR) and serologic an

94 The system utilizes automated repetitive sequence-based PCR (rep-PCR) and web-based da

95 detection of antibiotic resistance genes and repetitive sequence-based PCR (rep-PCR) assessments of c

96 g and analysis, is an automated method using repetitive sequence-based PCR (rep-PCR) for microbial st

97 Repetitive sequence-based PCR (rep-PCR) has been recogni

98 Repetitive sequence-based PCR (rep-PCR) showed minimal p

99 Clonality was assessed by repetitive sequence-based PCR (repPCR) and multilocus se

100 Repetitive sequence-based PCR and dendrogram analysis we

101 Fingerprinting of 16 isolates by repetitive sequence-based PCR showed that all were diffe

102 e typed by pulsed-field gel electrophoresis, repetitive sequence-based PCR typing, and rapid multiloc

103 olates was then subjected to high-resolution repetitive sequence-based PCR typing, which identified 1

104 Repetitive sequence-based PCR was found to be a technica

105 gularity extraction has focused primarily on repetitive sequence-based rules within the sensory envir

106 PCR-sequencing of bla genes, immunoblotting, repetitive-sequence-based PCR (rep-PCR) and multilocus s

107 Strain relatedness was assessed by repetitive-sequence-based PCR (rep-PCR) and pulsed-field

108 A commercially available repetitive-sequence-based PCR (rep-PCR) DNA fingerprinti

109 Repetitive-sequence-based PCR (rep-PCR) is useful for ge

110 Repetitive-sequence-based PCR (rep-PCR) using the Divers

111 The performance of repetitive-sequence-based PCR (rep-PCR) using the Divers

112 obacterial interspersed repetitive units and repetitive-sequence-based PCR (rep-PCR).

113 loid and the amplification and dispersion of repetitive sequences best explain the large genome size

114 complexity proteins; they are organized into repetitive sequence blocks and found to maintain homolog

115 hanism of repeat gain is dependent on highly repetitive sequence but, surprisingly, is independent of

116 . betularia W chromosome consists largely of repetitive sequence, but exceptionally we found a W homo

117 olkappa creates single-base deletions in non-repetitive sequences, but does not address how deletions

118 In addition to repetitive sequences, C(o)t-1 was found to be enriched f

119 Telomeric DNA usually consists of a repetitive sequence: C(1-3)A/TG(1-3) in yeast, and C(3)T

120 Toxic RNAs expressed from such repetitive sequences can be eliminated using CRISPR-medi

121 Centromeres and other repetitive sequences can drive in meiosis by cheating th

122 tial emergence of heterochromatin on various repetitive sequences changes their replication order and

123 ompanied by decreased H3K9 trimethylation of repetitive sequence chromatin.

124 n the temperature at which the most abundant repetitive sequence classes anneal and habitat thermal s

125 We find notable heterogeneity in repetitive sequence composition among the sequenced geno

126 vation along the chromosome, we compared the repetitive sequence composition of this region between t

127 s uniform gene density over chromosomes, low repetitive sequence content ( approximately 6%), and a h

128 o share genic features, they differ in their repetitive sequence content and composition suggesting t

129 lit between two subgenomes, with significant repetitive sequence content limiting the efficiency of r

130 papaya X; expansion is supported by a higher repetitive sequence content of the X compared with the p

131 genomes due to the large genome sizes, high repetitive sequence content, and rampant whole- or segme

132 he genuine leptin gene with a GC-rich ( 70%) repetitive-sequence content was identified in the chicke

133 nguished from tissue-specific genes by their repetitive sequence context.

134 that formation of non-B conformations by the repetitive sequence contributes to the expansion mechani

135 istical correlations there is a tendency for repetitive sequence density to be negatively correlated

136 Repetitive sequences derived from transposons make up a

137 ts fibronection and plasminogen by virtue of repetitive sequences-designated streptococcal surface re

138 tDNAs are repetitive sequences dispersed throughout the human geno

139 These trends in repetitive sequence distribution are strongly correlated

140 required for efficient H3K9me2 enrichment at repetitive sequences during chromocenter formation.

141 We found multiple copies of a repetitive sequence element termed RSR in genomes of spe

142 2 Mb due to a more accurate determination of repetitive sequence elements and assembled the complete

143 x1 to account for NOH-1S formation, we found repetitive sequence elements bordering the deleted regio

144 The fission yeast pericentromere comprises repetitive sequence elements packaged into heterchromati

145 a hypermutable region because of surrounding repetitive sequence elements that may catalyze the forma

146 heds new light on functional roles for short repetitive sequences embedded deep within introns throug

147 culties in sequencing through and assembling repetitive sequences enriched in the heterochromatin.

148 ng genes from tissue-specific genes and that repetitive sequence environment distinguishes housekeepi

149 as a measure of success, we demonstrate that repetitive sequence environment is by far the most impor

150 The distinct repetitive sequence environment, in combination with oth

151 -base deletion errors at high frequencies in repetitive sequences, especially those that contain two

152 se results suggest that pervasive intergenic repetitive sequence expression during human spermatogene

153 es (IESs), many of which belong to dispersed repetitive sequence families.

154 of small CRISPR RNAs (crRNAs) consisting of repetitive sequences flanking unique spacers to recogniz

155 Repetitive sequences follow a nonspecific pathway to ren

156 Among several different types of repetitive sequences found in the human genome, this stu

157 DNA methylation is essential for protecting repetitive sequences from aberrant transcription and rec

158 The ASGR includes highly repetitive sequences from an Opie-2-like retrotransposon

159 echanisms causes their insertions into other repetitive sequences, gene loci and other DNA.

160 ations result from strand slippage, which in repetitive sequences generates misaligned intermediates

161 EccDNA arose both from genomic regions with repetitive sequences >/= 15 bases long and from regions

162 of where to put a metal site along a linear, repetitive sequence has not been thoroughly addressed.

163 ences in other genera within these families, repetitive sequences have been combined into four databa

164 because alterations in these highly mutable repetitive sequences have been linked with many phenotyp

165 Since repetitive sequences have been reported to influence the

166 bably supported by an atypical complement of repetitive sequence in the genome.

167 Here, we describe another repetitive sequence in the human genome, the SVA element

168 n N-terminal catalytic domain and noncomplex repetitive sequence in the remainder of the molecule.

169 ted the role of genetic variation within the repetitive sequence in the transcriptional control regio

170 on 'slippage' events both create and destroy repetitive sequences in bacterial genomes.

171 and template-switching at the site of short repetitive sequences in DNA.

172 ut sequencing shows that Khd1 directly binds repetitive sequences in FLO11 mRNA.

173 volvement of transposable elements and other repetitive sequences in genome restructuring and gene re

174 Cross-hybridization of repetitive sequences in genomic and expression arrays is

175 nk." Yet, persistence of these tandem highly repetitive sequences in heterochromatic regions of most

176 pecific and orthogonal two-color labeling of repetitive sequences in living human cells using this me

177 ents (TEs) contribute to the large amount of repetitive sequences in mammalian genomes and have been

178 istinctive features of transposons and other repetitive sequences in Marchantia compared with floweri

179 space complexity for detecting most types of repetitive sequences in multiple scenarios, including fi

180 and to provide a resource for searching for repetitive sequences in other genera within these famili

181 Parallel analyses of repetitive sequences in potato and tomato revealed subst

182 f our genome, revealing a prominent role for repetitive sequences in shaping its structural variation

183 cation of specific regions between noncoding repetitive sequences in the bacterial genome.

184 The repetitive sequences in the coding regions primarily rep

185 (MSI) refers to the hypermutability of short repetitive sequences in the genome caused by impaired DN

186 er of Ac transposition events were to highly repetitive sequences in the genome.

187 some positioning motifs and the densities of repetitive sequences in the human genome.

188 rence genome due to sequencing errors and/or repetitive sequences in the reference.

189 h displayed different organization of highly repetitive sequences in the two genomes.

190 ed adhesins and virulence factors exhibiting repetitive sequences in their core structure.

191 ficant differences were identified in highly repetitive sequences, including centromere, 45S ribosoma

192 profound de-repression of several classes of repetitive sequences, including major satellite, LINE-1,

193 methylation in tumors occurs specifically at repetitive sequences, including short and long intersper

194 Transcribed genomic repetitive sequences, including simple centromeric repea

195 Approximately 76% of the region contained repetitive sequences, including transposon-like sequence

196 opy number estimates including all dispersed repetitive sequences indicate that 40%-65% of each genom

197 Although highly diverse, their repetitive sequences induce DNA polymerase slippage and

198 abundance short interfering RNAs that match repetitive sequences, intergenic regions and genes.

199 e small interfering RNAs (siRNAs) that match repetitive sequences, intergenic regions, and genes.

200 We also identify 1.3 Mb of non-repetitive sequence interspersed with HSat2,3 across 17

201 ely 80% of the maize genome comprises highly repetitive sequences interspersed with single-copy, gene

202 A repetitive sequence is found in the D. pseudoobscura gen

203 PCR amplification over GC-rich and/or long repetitive sequences is challenging because of thermo-st

204 Moreover, we show that this core of repetitive sequences is expressed throughout the nucleus

205 t generic method for detecting most types of repetitive sequences is still desirable.

206 epair efficiencies of DNA damage within such repetitive sequences is therefore crucial for understand

207 volving subtelomere - the telomere-adjacent, repetitive sequence - is a primary driver of the 'telome

208 mina approaches reveal only a portion of the repetitive sequence landscape of eukaryotic genomes and

209 whole-genome assembly due to an abundance of repetitive sequence, leading to the development of gene-

210 m analysis with a highly polymorphic GC-rich repetitive sequence located in the plasmid pTBN12 (PGRS

211 f ICF patients, including hypomethylation of repetitive sequences, low body weight, distinct cranial

212 f human non-protein-coding DNA is made up of repetitive sequences, mainly transposable elements (TEs)

213 Repetitive sequences make up a significant fraction of a

214 ence content and composition suggesting that repetitive sequences may have a more significant role in

215 c RNA, but also demonstrate that ligands for repetitive sequences may have unexpected effects on RNA

216 a suggest that transcription of interspersed repetitive sequences may represent a developmental strat

217 hey suggest that the residues flanking these repetitive sequences may represent viable therapeutic ta

218 Genes composed of tandem repetitive sequence motifs are abundant in nature and ar

219 malignancies that is distinguished by highly repetitive sequences ("mucin repeats") in the extracellu

220 p to 13 Mbp) and smaller hotspots flanked by repetitive sequence (n = 1,247, median size 79 kbp, rang

221 ncluding the constitutive heterochromatin on repetitive sequences near centromeres and telomeres, nee

222 Repetitive sequences need not be matched to a query, if

223 bonuclease Csy4, which binds and cleaves the repetitive sequence of the CRISPR transcript.

224 ed-coil domain and associates densely on the repetitive sequence of the phosphorylated CTD via its N-

225 abolition of NFC101/NFC102 association with repetitive sequences of different transposable elements

226 Despite the GC-rich, highly repetitive sequences of ELPs, we synthesized remarkably

227 molecules and integrate them in between the repetitive sequences of the CRISPR array in the form of

228 oligonucleotide arrays that tile all the non-repetitive sequences of the human genome at 35 bp resolu

229 Telomeres are repetitive sequences of variable length at the ends of c

230 rge and complex genomes containing extensive repetitive sequences, of which the bulbous and monocotyl

231 s on whether the genomic context is tandemly repetitive sequences often found near centromeres, which

232 ecombination is more likely to occur between repetitive sequences on nonhomologous chromosomes.

233 Thus, dynamic DNA methylation changes within repetitive sequences or transposons can regulate neighbo

234 unusual amino acid composition and extensive repetitive sequence organised into two defined repeat re

235 Close to 50% of the human genome harbors repetitive sequences originally derived from mobile DNA

236 c elements (MGEs) will make up much of these repetitive sequences, particularly the interspersed sequ

237 nce and mutator status and were genotyped by repetitive-sequence PCR (rep-PCR), pulsed-field gel elec

238 We performed a blinded study to compare repetitive-sequence PCR and multilocus sequence typing f

239 Molecular typing was done by repetitive-sequence PCR to define distinct S aureus stra

240 n, and the CTV-05 strain was discerned using repetitive-sequence polymerase chain reaction DNA finger

241 typing of S aureus strains was performed by repetitive-sequence polymerase chain reaction to determi

242 on and errors in the human reference genome, repetitive sequences, polymorphisms, variable sample qua

243 However, the presence of tandem repetitive sequences prevents pre-assembly of long reads

244 he proline glutamic acid-polymorphic GC-rich repetitive sequences protein family of M. tuberculosis.

245 HPV-EM, to address the ambiguities caused by repetitive sequencing reads.

246 To examine the stability of repetitive-sequence (rep) PCR profiles, six species of b

247 keeping genes while various longer (>400-bp) repetitive sequences ("repeats"), including Long Intersp

248 Thus, our study reveals a potential shift in repetitive sequence representation between these extreme

249 themselves consist largely of 125 and 102 bp repetitive sequences, respectively, and encode basic pro

250 se two species including a telomeric-related repetitive sequence, ribosomal DNA, and a number of uncl

251 ns a prion-forming domain characterized by a repetitive sequence rich in Gln, Asn, Tyr, and Gly amino

252 f the maize (Zea mays L.) genome consists of repetitive sequences, sequencing efforts are being targe

253 f its disordered, atypically hydrophilic and repetitive sequence signatures.

254 otably, with sgRNAs targeted to standard non-repetitive sequences, SpCas9-HF1 rendered all or nearly

255 s showed that this BAC consists primarily of repetitive sequences such as a 102-bp tandem repeat with

256 Repetitive sequences such as satellite DNAs are potentia

257 Repetitive sequences such as transposable elements trigg

258 nism for silencing transgenes and endogenous repetitive sequences such as transposons.

259 the human and mouse genomes are comprised of repetitive sequences, such as transposable elements (TEs

260 polymerase eta, decreased 10-fold before the repetitive sequence, suggesting that the polymerase was

261 in the rat medial prefrontal cortex during a repetitive sequence task were preserved during subsequen

262 Genome features, such as repetitive sequences, telomeres, conserved syntenic bloc

263 Selected repetitive sequences termed short inverted repeats (SIRs

264 smaller size are more capable of recovering repetitive sequences than those of bigger size.

265 age occurs when an RNA transcript contains a repetitive sequence that allows the transcript to slip b

266 density in DNA flanking both sides of a 1-kb repetitive sequence that forms the core of the switch re

267 Spider silk genes are composed mostly of repetitive sequence that is flanked by non-repetitive te

268 The genome is burdened with repetitive sequences that are generally embedded in sile

269 Telomeres are composed of repetitive sequences that can be maintained by telomeras

270 Replication slippage is induced at repetitive sequences that can be very small and tend to

271 tantial portion of the genome is composed of repetitive sequences that can hinder genome annotation a

272 to uncover mapped genomic sites from highly repetitive sequences that can not be detected based on u

273 The genome has ~25% repetitive sequences that have been affected by repeat-i

274 ntronic DNA or in the distribution of middle repetitive sequences that have teleregulatory impact.

275 nomes harbor transposable elements and other repetitive sequences that must be silenced.

276 lex eukaryotic genomes, consisting of highly repetitive sequences that resist mapping, cloning and se

277 m and P. vivax to identify species-specific, repetitive sequences that serve as new PCR targets for t

278 DNA elimination reveals that in all species, repetitive sequences (that differ among the genera) and

279 n ancestor of the Brassica and, unlike other repetitive sequences, there is no evidence for genome-wi

280 ase counteracts chromosome erosion by adding repetitive sequence to terminal ends.

281 We developed a model telomere lacking repetitive sequences to study the distribution of HipHop

282 Activation of repetitive sequence transcription is accompanied by decr

283 ped developmental program in which different repetitive sequences use distinct interactions and indep

284 been made in pinpointing variations in these repetitive sequences using whole-genome sequencing.

285 n intergenic regions consisting primarily of repetitive sequences vary substantially along the loci a

286 sites of long interspersed nuclear element-1 repetitive sequences was assessed in a group of 63 patie

287 ere sequenced, annotated and the presence of repetitive sequences was determined.

288 On non-repetitive sequences, we find that nucleotide misincorpo

289 ciated changes in chromatin accessibility at repetitive sequences, we suggest that replication gaps r

290 Specific classes and types of repetitive sequences were also differentially represente

291 Very few repetitive sequences were detected, and the process of r

292 and maintenance remain elusive especially at repetitive sequences, which account for the majority of

293 site resulted in homologous recombination of repetitive sequences, which is required for gene silenci

294 The first capture depletes the library of repetitive sequences, while the second enriches for targ

295 In the course of a search for any type of repetitive sequences whose copy numbers have substantial

296 a large sex chromosome composed primarily of repetitive sequences with a large number of Copia and Gy

297 Rs belong to a broader group of weak-folding repetitive sequences with potential regulatory roles.

298 can be used to identify issues in assembly, repetitive sequences within transcripts and splice varia

299 ffsets aberrant behavior caused by excessive repetitive sequences without compromising its targeting

300 Finally we describe a novel repetitive sequence, wtf, which was also preferentially